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A. Everette James, Jr. Lecture in Radiological Sciences by Etta D. Pisano, M.D. CCC-1111 Medical Center North 21st Avenue South & Garland Vanderbilt University Medical Center Nashville, Tennessee NOVEMBER 17, 2011 Vanderbilt University School of Medicine Department of Radiology & Radiological Sciences and The Division of Continuing Medical Education present the Sixteenth Annual A. Everette James, Jr., Sc.M., M.D. Everette James grew up in a farm community in the coastal plain of North Carolina and is an honors graduate of the University of North Carolina and Duke University Medical School. His post-doctoral work was at Johns Hopkins School of Public Health, Harvard Medical School, and as Honorary Fellow of the Royal Society of Medicine of England. He is a graduate of the Program of Health Systems Management at the Harvard Business School. He was a Picker Advanced Academic Fellow under Russell H. Morgan at Johns Hopkins. James served as a radiologist in Vietnam where he received the Army Commendation Medal and was recommended for the Bronze Star. Later he was given the Leadership Award for efforts on behalf of Vietnam Veterans and contributions to the committee for the Vietnam Veterans Memorial. James' professional appointments include: Harvard Teaching Fellow (1968-1969); Associate Professor, Director of Radiological Research Laboratories at Johns Hopkins Medical School (1971-75); Chair and Professor of Radiological Sciences at Vanderbilt University School of Medicine; Lecturer in Legal Medicine, Department of Medical Administration at Vanderbilt; Senior Research Associate, Vanderbilt Institute for Public Policy. He founded the Center for Medical Imaging Research (1975-93). For over 20 years of his career, he served as a consultant to the National Zoo of the Smithsonian and as a member of the National Council of Radiation Protection (NCRP). James was a Scholar of the Institute of Medicine, a Visiting Scientist at the National Cancer Institute/National Institutes of Health in 1991-92 and Senior Program Officer of the National Academy of Sciences (IOM) in 1993-94, all in Washington, D.C. In 1994-95 he served the Special Advisor to the Governor of North Carolina and Board of Science and Technology. Presently he is a Lecturer at Johns Hopkins Medical Schools, Adjunct Professor of Radiology at Vanderbilt, and Clinical Professor at the University of North Carolina at Chapel Hill. Dr. James is past President of the Society of Chairmen of Academic Radiology Departments (SCARD), past President of the Association of University Radiologists (AUR), and past President of the American Roentgen Ray Society (ARRS). He has received the Gold Medal Award from both AUR and ARRS. James was given the Distinguished Graduate Award of Duke University Medical School in 1993 and in 2002 received the Medical School’s Humanitarian Award. Dr. James served as a member of the Duke University Medical School Board and is currently a member of the James B. Duke Society and the Davison Club. He is also a member of Alpha Omega Alpha. He is a member of the Explorer’s Club of New York and the Cosmos Club of Washington and served on the Art Committee of the Cosmos Club. James served as a member of the board of the North Carolina State University Veterinary Medicine Foundation and was President of the Board from 1997-98. He was inducted into the Riddick Society of North Carolina State University. At the University of North Carolina at Chapel Hill, he was a founding member of the Parent’s Council for Out-of-State Students, has served on the Board of Visitors, and is presently a member of the Chancellor’s Club and the Advisory Committee for the Center for the Study of the American South. At Johns Hopkins University, he was a member of the Dean’s Committee in the Bloomberg School of Public Health and a member of the Presidents Society. He served as Radiology Representative to the AMA, the American Association of Medical Colleges and the Administrative Board of the Council of Academic Societies. Dr. James is affiliated with numerous state and national art-related organizations and museum boards. He served on the founding board of the American Visionary Art Museum in Baltimore. He was a founding board member of the International Association of Art in Medicine and cover editor of the journal, IJAM. Dr. James is on the Board of Directors, North Carolina Pottery Center, and serves on a Regional Advisory Committee for Preservation North Carolina. He has been a guest curator and lecturer on many art forums both nationally and internationally. His collections of 19th and early 20th century American art, North Carolina art pottery, North Carolina quilts, North Carolina waterfowl decoys, have been widely exhibited in the South. roughout his career, he brought an arts focus to radiology specifically, and to medicine in general. Dr James is a Tennessee Squire and a Kentucky Colonel. He is a member of Leadership Nashville and a Life member of Vietnam Veterans. Dr. James is the author of over 540 articles and 23 books on medicine, law, ethics, art, folklore, and fiction. His most recent publications have been North Carolina Art Pottery and Collecting American Art. He is listed in many Who’s Who including Who’s Who in Art. In 1994, James won the North Carolina Carraway Award for Historic Preservation for restoring a primitive Baptist church in his hometown and converting it into a free-to-the-public museum devoted to Southern folklore. e church is now on the National Register of Historic Places. He also restored the Bank of Robersonville under the guidance of Preservation North Carolina and the National Trust. He later gifted the Bank to Preservation North Carolina. He has donated paintings to many museums and organizations including the Boston Athenaeum, Massachusetts General Hospital, Tufts Medical School, Johns Hopkins Hospital, Duke University Hospital, Cheekwood Art Museum, the Mint Museum, the Morris Museum, Mobile Museum of Art, Tennessee Museum of Art, the Cowan Collection at the Parthenon, Hickory Museum of Art, Asheville Museum of Art, Marion Arts Council, North Carolina State University Gallery of Art and Design, the Ackland Art Museum, and numerous local museums and collections. Additionally, Dr. James has given collections to the Cosmos Club, Vanderbilt University, Fisk University, Pfeiffer University, Greensboro College, the Martin County Courthouse, the University of North Carolina, North Carolina State University School of Veterinary Medicine, the John Hope Franklin Center, Duke University, the American Roentgen Ray Society, Johns Hopkins School of Hygiene, and the Center for Academic Honors at the University of North Carolina. Dr. James and his wife have donated North Carolina pottery collections to the North Carolina Pottery Center and the Chapel Hill Museum. ey recently donated their African/American quilt collection to the North Carolina Museum of History and had given the Pattie Royster James Collection of 102 NC quilts to NC State University. Everette James has three children: Everette James, III; Jeannette James Whitson, and Elizabeth Royster James, all three graduates of the University of North Carolina at Chapel Hill. He is married to Nancy J. Farmer. Residing in Chapel Hill, Drs. James and Farmer are active in civic and community affairs.

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A. Everette James, Jr. Lecturein Radiological Sciences

by Etta D. Pisano, M.D.

CCC-1111 Medical Center North21st Avenue South & Garland

Vanderbilt University Medical CenterNashville, Tennessee

November 17, 2011

Vanderbilt University School of MedicineDepartment of Radiology & Radiological Sciencesand The Division of Continuing Medical Education

present the Sixteenth Annual

A. Everette James, Jr., Sc.M., M.D.Everette James grew up in a farm community in the coastal plain of North Carolina and is an honors graduate of the University of North Carolina and Duke University Medical School. His post-doctoral work was at Johns Hopkins School of Public Health, Harvard Medical School, and as Honorary Fellow of the Royal Society of Medicine of England. He is a graduate of the Program of Health Systems Management at the Harvard Business School. He was a Picker Advanced Academic Fellow under Russell H. Morgan at Johns Hopkins.James served as a radiologist in Vietnam where he received the Army Commendation Medal and was recommended for the Bronze Star. Later he was given the Leadership Award for efforts on behalf of Vietnam Veterans and contributions to the committee for the Vietnam Veterans Memorial.James' professional appointments include: Harvard Teaching Fellow (1968-1969); Associate Professor, Director of Radiological Research Laboratories at Johns Hopkins Medical School (1971-75); Chair and Professor of Radiological Sciences at Vanderbilt University School of Medicine; Lecturer in Legal Medicine, Department of Medical Administration at Vanderbilt; Senior Research Associate, Vanderbilt Institute for Public Policy. He founded the Center for Medical Imaging Research (1975-93). For over 20 years of his career, he served as a consultant to the National Zoo of the Smithsonian and as a member of the National Council of Radiation Protection (NCRP).James was a Scholar of the Institute of Medicine, a Visiting Scientist at the National Cancer Institute/National Institutes of Health in 1991-92 and Senior Program Officer of the National Academy of Sciences (IOM) in 1993-94, all in Washington, D.C. In 1994-95 he served the Special Advisor to the Governor of North Carolina and Board of Science and Technology.Presently he is a Lecturer at Johns Hopkins Medical Schools, Adjunct Professor of Radiology at Vanderbilt, and Clinical Professor at the University of North Carolina at Chapel Hill.Dr. James is past President of the Society of Chairmen of Academic Radiology Departments (SCARD), past President of the Association of University Radiologists (AUR), and past President of the American Roentgen Ray Society (ARRS). He has received the Gold Medal Award from both AUR and ARRS.James was given the Distinguished Graduate Award of Duke University Medical School in 1993 and in 2002 received the Medical School’s Humanitarian Award. Dr. James served as a member

of the Duke University Medical School Board and is currently a member of the James B. Duke Society and the Davison Club. He is also a member of Alpha Omega Alpha. He is a member of the Explorer’s Club of New York and the Cosmos Club of Washington and served on the Art Committee of the Cosmos Club. James served as a member of the board of the North Carolina State University Veterinary Medicine Foundation and was President of the Board from 1997-98. He was inducted into the Riddick Society of North Carolina State University.At the University of North Carolina at Chapel Hill, he was a founding member of the Parent’s Council for Out-of-State Students, has served on the Board of Visitors, and is presently a member of the Chancellor’s Club and the Advisory Committee for the Center for the Study of the American South.At Johns Hopkins University, he was a member of the Dean’s Committee in the Bloomberg School of Public Health and a member of the Presidents Society. He served as Radiology Representative to the AMA, the American Association of Medical Colleges and the Administrative Board of the Council of Academic Societies.Dr. James is affiliated with numerous state and national art-related organizations and museum boards. He served on the founding board of the American Visionary Art Museum in Baltimore. He was a founding board member of the International Association of Art in Medicine and cover editor of the journal, IJAM. Dr. James is on the Board of Directors, North Carolina Pottery Center, and serves on a Regional Advisory Committee for Preservation North Carolina.He has been a guest curator and lecturer on many art forums both nationally and internationally. His collections of 19th and early 20th century American art, North Carolina art pottery, North Carolina quilts, North Carolina waterfowl decoys, have been widely exhibited in the South. Throughout his career, he brought an arts focus to radiology specifically, and to medicine in general.Dr James is a Tennessee Squire and a Kentucky Colonel. He is a member of Leadership Nashville and a Life member of Vietnam Veterans.Dr. James is the author of over 540 articles and 23 books on medicine, law, ethics, art, folklore, and fiction. His most recent publications have been North Carolina Art Pottery and Collecting American Art. He is listed in many Who’s Who including Who’s Who in Art.In 1994, James won the North Carolina Carraway Award for Historic Preservation for restoring a primitive Baptist church in his hometown and converting it into a free-to-the-public museum devoted to Southern folklore. The church is now on the National Register of Historic Places. He also restored the Bank of Robersonville under the guidance of Preservation North Carolina and the National Trust. He later gifted the Bank to Preservation North Carolina.He has donated paintings to many museums and organizations including the Boston Athenaeum, Massachusetts General Hospital, Tufts Medical School, Johns Hopkins Hospital, Duke University Hospital, Cheekwood Art Museum, the Mint Museum, the Morris Museum, Mobile Museum of Art, Tennessee Museum of Art, the Cowan Collection at the Parthenon, Hickory Museum of Art, Asheville Museum of Art, Marion Arts Council, North Carolina State University Gallery of Art and Design, the Ackland Art Museum, and numerous local museums and collections. Additionally, Dr. James has given collections to the Cosmos Club, Vanderbilt University, Fisk University, Pfeiffer University, Greensboro College, the Martin County Courthouse, the University of North Carolina, North Carolina State University School of Veterinary Medicine, the John Hope Franklin Center, Duke University, the American Roentgen Ray Society, Johns Hopkins School of Hygiene, and the Center for Academic Honors at the University of North Carolina.Dr. James and his wife have donated North Carolina pottery collections to the North Carolina Pottery Center and the Chapel Hill Museum. They recently donated their African/American quilt collection to the North Carolina Museum of History and had given the Pattie Royster James Collection of 102 NC quilts to NC State University.Everette James has three children: Everette James, III; Jeannette James Whitson, and Elizabeth Royster James, all three graduates of the University of North Carolina at Chapel Hill. He is married to Nancy J. Farmer. Residing in Chapel Hill, Drs. James and Farmer are active in civic and community affairs.

12:00 pm Welcome and Introduction of the James Lecturer

Arthur C. Fleischer, M.D.Cornelius Vanderbilt Professor of

Radiology & Radiological Sciences

12:10 pm THE A. EVERETTE JAMES, JR. LECTURE“What We Learned from DMIST and What We Still Need

to Know About Breast Cancer Screening”

Etta D. Pisano, MD

Dean, College of MedicineVice President for Medical Affairs

Medical University of South CarolinaCharleston, SC

P R O G R A M

Targeted audience: Designed for faculty, residents, staff and medical students.

Objective:1. To understand the results of DMIST regarding the diagnostic accuracy of film and digital mammography;2. To understand the results of DMIST regarding cost effectiveness;3. To understand the most likely causes of the results of DMIST.

Vanderbilt School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physi-cians. Vanderbilt School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Jeff Creasy, M.D., course Director, has no financial relationships related to the content of this activity to disclose. Etta Pisano, M.D., presenter, has the following relationships to disclose: Koning Corporation, Contract Research Grant; NextRay, Inc., share holder; Sectra, Contract Research Grant.

This educational activity received no commercial support. Vanderbilt CME has determined that there are no conflicts of interest.

Etta D. Pisano, MDDr. Etta Pisano joined the Medical University of South Carolina (MUSC) as Vice President for Medical Affairs and Dean of the College of Medicine on July 1, 2010. Prior to accepting the position at MUSC, Etta served as Vice Dean for Academic Affairs at the University of North Carolina (UNC) School of Medicine, Kenan Professor of Radiology and Biomedical Engineering, Director of the UNC Biomedical Research Imaging Center, and Director of the N.C. Translational and Clinical Sciences Institute. She is an expert in breast cancer imaging and, from 1989 to 2005, she served as the Chief of Breast Imaging at UNC Hospitals. Her undergraduate degree in Philosophy is from Dartmouth College and her medical degree is from Duke University. Etta’s professional interests center around the development, application and testing of imaging technology for the early detection and diagnosis of breast cancer and other breast problems.Etta was born in New York City and was raised in the suburbs of Philadelphia. After completing a rotating internship in a community-based program in Pensacola, Florida, she completed her radiology residency at Beth Israel Hospital of Harvard Medical School. After her residency, she spent a year as Chief of Breast Imaging and Instructor in Radiology at the same institution. She is a Past President of the Association of University Radiologists and the American Association for Women Radiologists, and has been named by Diagnostic Imaging magazine as one of the 20 most influential people in radiology. Recently, Etta served as the Principal Investigator of the largest clinical trial ever run by a radiologist, the Digital Mammographic Imaging Screening Trial (DMIST), which enrolled 49,528 women in a study comparing digital to film mammography, the results of which were published in 2005 in the New England Journal of Medicine. Etta was awarded one of the first Ladies’ Home Journal Health Breakthrough Awards. In 2003, she was appointed the first Director of the UNC Biomedical Research Imaging Center, a core facility that develops and commercializes new imaging technologies. She successfully raised over $20 million from private donors, industry and the university to support its activities. In 2008 she was elected as a member of the Institute of Medicine of the National Academy of Sciences.Recently she co-founded her own company, NextRay, Inc, which will commercialize a device she and the other cofounders invented, a technology which creates medical images using x-rays through diffraction enhanced imaging which provides superior image quality at a dose that is substantially lower than is currently available. This will be most important to children and young adults, and young women undergoing breast cancer screening.Her husband, Jan Kylstra, is on the faculty at MUSC; he is an ophthalmologist with a subspecialty in retina. He grew up in Durham, North Carolina. They have four children, two girls and two boys, ranging in age from 25 to 16, and they spend the majority of their free time with them and attending their activities. Their hobbies are hiking, watersports, reading, and travel.

PREVIOUS JAMES LECTURERS1995 Charles E. Putman, M.D. Duke University1996 Gerald S. Freedman, M.D. Yale University1997 David G. Bragg, M.D. National Institute of Health1998 Robert I. White, M.D. Yale University1999 Jeffrey H. Newhouse, M.D. Columbia University2000 Lee F. Rogers, M.D. Wake Forest University2001 Christopher R.B. Merritt, M.D., FACR Thomas Jefferson University2002 William M. Thompson, M.D. Duke University2004 Arthur C. Fleischer, M.D. Vanderbilt University2005 James H. Thrall, M.D. Harvard University2006 Jonathan B. Kruskal, M.D., Ph.D. Harvard University2007 N. Reed Dunnick, M.D. University of Michigan2008 William Bradley, Jr., M.D. University of California, San Diego2009 Robert Mattrey, M.D. University of California, San Diego2010 Stephanie R. Wilson, MD University of Calgary