A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING

• Over 100 Full-Time Scientists - Many Disciplines Nutrition, Medicine Pharmacology, Biochemistry, Dietetics, Toxicology, Immunology, Physics, Biomedical Engineering• Dr. Joseph Chang - Chief Scientific Officer Photodynamic Cancer Therapy Drug (Brain Tumors) Etodolic (Arthritis Drug) Rapamune (Anti-Rejection Drug)• Research Partners - Purdue University, Life Gen Technologies, Stanford University, Harvard University • Anti-Aging Scientific Advisory Board - 20 Scientists• 3 Global Research Centers Power NSE’s Research and

Development Engine

SCIENCE IS THE ENGINE DRIVING NSE’s INNOVATION

Huzhou Mfr. PlantShanghai R&D Center

Beijing Clinical Center Provo, Utah Headquarters & Pharmanex Research Institute

Over 100 Scientists

NSE IS THE ONLY SCIENCE-BASED COMPANY WITH 2 ANTI-AGING PRODUCT BRANDS

ageLOC Skin Care= ageLOC OUTSIDE

ageLOC Nutritionals= ageLOC INSIDE

PHARMANEX SCIENCE + NU SKIN GUARANTEE:• QUALITY• INNOVATION• SAFETY• SUBSTANTIATED CLAIMS

• 25 Successful Years• Publicly Traded on NYSE (NUS)• Dunn & Bradstreet 5A1 Rating• Operating in 50 Countries• $1.3 Billion in Annual Sales 2009• 2010 Projected Annual Sales Over

$1.6 Billion = 23% Increase!• Over $770 Million in Assets• Over $180 Million in Cash• Over $350 Million Spent on R&D• Recognized & Featured in Numerous

Media, Including Forbes Magazine & Investors Business Daily

NSE – THE COMPANY BEHIND ageLOC

NU SKIN—YOUR TRUSTED PARTNER

+19%

Top 5 Mid-Cap Company

• A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING

• A PLATFORM OF INNOVATIVE ANTI-AGING SOLUTIONS THAT TARGET AGE-RELATED GENES = THE ULTIMATE SOURCES OF AGING

WHAT IS ?

9

THE GENE REVOLUTION

• 1953: James Watson and Francis Crick identify the structure of the DNA molecule

• 2003: The Human Genome is sequenced & the map is completed

• 2010: An entire new branch of science emerges

GENE SCIENCE IS THE HOT TOPIC IN THE MEDIA

• Old Paradigm: There is nothing you can do to influence your inherited genes and aging is inevitable.

• ageLOC Paradigm: Genes respond to the environment. Gene action & expression can be influenced and be restored to a more youthful state through targeted ingredient introduction.

GENESIS OF AGELOC• Identification of age-related genes by

pioneers of aging research• Exclusive collaboration with LifeGen to

develop gene-based anti-aging products• ageLOC creates a sustainable competitive

advantage with exclusive access to over 30 years of research into the genetic basis of aging.

1. IDENTIFY groups or clusters of genes which impact aging and understand their youthful expression patterns (Youth Gene Clusters or YGC’s);

2. ISOLATE - Investigate the aging effect of different ingredients on specific YGC’s in human tissues;

3. RESET - Develop formulae that reset these YGC’s back to their youthful state.

SCIENCE SIMPLIFIED

ageLOC BALANCES YGC ACTIVITY

Genes that promote YOUTH

Genes that ACCELERATE

aging

Is it Safe to Influence Genes?

X-MENageLOC is NOT:

gene therapy genetic engineeringgene splicing

ageLOC IS:

Nu Skin’s novel approach to developing products designed to support youthful gene expression.

ageLOC SCIENCE VALIDATED

Genetics of Aging Symposium

University of Tokyo

Stimulant-free cellular energy

A MASS MARKET PRODUCT EVERYONE WANTS AT A PRICE EVERYONE CAN AFFORD!

• ageLOC science applied to internal body tissues – heart, brain & muscle tissues

• Influences genetic expression through targeted nutritional supplementation

• Clinically proven to increase PHYSICAL ENERGY, MENTAL ACUITY & SEXUAL DESIRE

• Only $50 for a month = $1.66/day!!!

IS NOT - A stimulant, drug, or chemicalsIS - A proprietary BLEND of mushroom, ginseng, and pomegranate (a fruit, a root & a fungus) that have been thoroughly studied and proven safe, combined in clinical doses to influence our genetic expressionIS - The result of 30+ years of research by hundreds of doctors & scientists, multiple patents, and hundreds of millions of dollars in R&D

• Mitochondria are the cellular power plants that convert energy from food (Kcals) into a form of energy our cells can use—ATP

• ATP fuels all biological functions• With age, mitochondria number and efficiency declines

dramatically• Mitochondria dysfunction leads to age-related vitality loss

MITOCHONDRIA: A KEY SOURCE OF YOUTHFUL VITALITY

Brain

Heart

Muscle

MITOCHONDRIA HIGHLY CONCENTRATED IN:

LATEST ageLOC DISCOVERY:

Identified and influenced 52 genes tied to mitochondrial function

ageLOC SCIENCE DISCOVERS THE GENETIC MECHANISM TO OPTIMIZEMITOCHONDRIAL POWER GENERATION

RESTORE YOUTHFUL VITALITY

ageLOC Vitality targets the sources of age-related vitality loss by promoting youthful expression of mtYGC.

BOTTOM LINE RESULTS• Increased and sustained baseline ENERGY levels with NO stimulant effect• Increased mental clarity, focus, ability to concentrate & productivity• Increased libido• More restful sleep and refreshed mornings• Increased endurance & strength• Better food choices & less appetite• Regulated blood sugar• Fewer aches and pains

Energy drink market = $14 Billion!

A Global Consumer Need NO COMPARISON

•Demographic agnostic•Increases energy and mental clarity •Results in 7-12 days •NO stimulants•Price friendly - $50 for 180 capsules

Available NOW in 6-packs!!! Will be available individually at the launch

in January 2011

$1.66 per day

GENE-BASED ANTI-AGING FROM THE OUTSIDE IN

Anti-Aging Innovation

Download MediaiTunes Store

Proprietary Device with ConsumableGels & Complementary Products

Reducing the Size of Technology

Instant Results – Unique, Emotional, Affordable!

ageLOC Galvanic Spa System II

• Smoothes Lines and Wrinkles• Lifts and Increases Skin Firmness• Micro Cleanses Skin to Dermal Layer• Improves Skin Texture and Pore Size• Treatment Takes Only 5 Minutes 2-3/wk!

Hand-held Patented Technology

Reduce the Visible Signs of Aging

VALUE Galvanic ageLOC Spa Package = $290

» Galvanic Spa Device – Can be used with ANY daily skin care regimen

» 4 Interchangeable Heads» 8 Sets of Facial Treatment Gels (1 month)

» 1 NaPCA Moisture Mist (1 month)

» Cost per Treatment (after 1st 8 treatments)= $7.50!!!

The Most Advanced Product in Nu Skin History!

► Maximum concentration of ageLOC ingredients

► ageLOC & other anti-aging ingredients clinically proven to significantly improve skin in 8 ways

FUTURE SERUM

Four YGCs Identified That Are Responsible for 8 Signs of Skin Aging

ageLOC Science

Skin Structure

Pigmentation

Hydration

Cellular Turnover

Youth Gene Clusters Fine Lines & Wrinkles

Youthful Skin

Structure

Discoloration

Skin Tone

Hydration

Texture, Smoothness

Radiance

Pore Size

8 Signs of Aging

ageLOC Results

► Can be used with ANY daily skin care regimen

► Twice daily application► $157 for 30 day supply► Compare to leading anti-aging

serums:– Chanel – Subimage = $400.00– Estee Lauder – Re-Nutriv = $140.00– Lancome – Secret De Vie = $265.00– La Prairie – Radiance Collection =$570.00

FUTURE SERUM

VALUE

The Modern Essentials of Anti-AgingageLOC Elements

► Gentle Cleanse & Tone = $35

► Radiant Day SPF 22 = $47.50

► Transforming Night = $55► Foundational ageLOC

regimen ► 30-60 day supply► VERY competitively priced

at $125

ageLOC ANTI-AGING SOLUTIONS

ageLOC Launch vs. g3 and Lifepak

1 2 3 4 5 6 7 8 $-

$5,000,000

$10,000,000

$15,000,000

$20,000,000

$25,000,000

$30,000,000

$35,000,000

$40,000,000

Lifepakg3ageLOC

IN FIRST 8 QUARTERS

Q1 2010 Projected $35 Million

Q1 2010 Over $55 MillionQ2 2010 Over $65 MillionQ3 2010 TBA NOV 3! VITALITY > $11 Million in 2 weeks!

11

Q4 09 Q1 10

= 43%!

$16,

133

$55,

980

$535

,276

$5, 6

0 7

$9,9

8 0

$32 ,

170

$124

,104

Does this look interesting?

2009 Nu Skin Average Annual Incomes

* The stated bonus commissions do not represent a distributor’s profit, as they do not consider expenses incurred by a distributor in the promotion of his/her business. You should always use good judgment in determining the amount of product you purchase. Your expenditure for products should not exceed what you can afford and what you believe you can resell or consume during any given month. For a complete summary of distributor earnings/bonuses paid to distributors at all levels within the Sales Compensation Plan, please contact the company at 800-487-1000 or see the end of this presentation or visit www.nuskinenterprises.com.

EXEC 1 2 4 6 8 12

HOW MANY PEOPLE DO YOU KNOW WHO WANT MORE ENERGY?MORE MENTAL CLARITY?MORE LIBIDO?AND WOULD PAY $60 FOR IT?

20? 10?

5?

THE QUESTION NOW IS

$300 $600 $1200

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