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1 8 - 10 JANUARY, 2021 VIRTUAL SUMMIT APBCS E-BROCHURE ORGANIZED BY APBCS.ORG ACCESS VIRTUAL PLATFORM

8 - 10 JANUARY, 2021 VIRTUAL SUMMIT...PROFESSOR, THE ROYAL MARSDEN NHS FOUNDATION TRUST UNITED KINGDOM. 7 REGIONAL SPEAKERS AMY CHOW ASSOCIATE PROFESSOR, DEPARTMENT OF SOCIAL WORK

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  • 1

    8 - 10 JANUARY, 2021 VIRTUAL SUMMIT

    APBCS E-BROCHURE

    ORGANIZED BY

    APBCS.ORG

    ACCESS VIRTUAL PLATFORM

    https://events.index.ae/apbcs-2021/login

  • 2

    CONTENTTABLE OF

    Organizing & Scientific Committee 3

    International Speakers 4

    Regional Speakers 7

    Local Speakers 9

    Program at Glance 12

    Best of San Antonio Breast Cancer Symposium Program 13

    Oncology Nursing Session 15

    APBCS Agenda - Day 1 16

    APBCS Agenda - Day 2 18

    Sponsors 23

  • 3

    SHAHEENAH DAWOODUAE

    SHAHEENAH DAWOODUAE

    REBECCA DENTSINGAPORE

    LEE SOO CHINSINGAPORE

    LEE SOO CHINSINGAPORE

    NAN SOON WONG SINGAPORE

    GEOK HOON LIM SINGAPORE

    MAY LENG MABEL TAN SINGAPORE

    ORGANIZING COMMITTEE

    SCIENTIFIC COMMITTEE

    REBECCA DENTSINGAPORE

  • 4

    ADAM BRUFSKYASSOCIATE CHIEF, DIVISION OF HEMATOLOGY/ONCOLOGY DIRECTOR, COMPREHENSIVE BREAST CANCER CENTER UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE USA

    ADITYA BARDIAMOLECULAR ONCOLOGIST, MASSACHUSETTS GENERAL HOSPITAL USA

    CHARLES PEROUPROFESSOR, LINEBERGER COMPREHENSIVE CANCER CENTER USA

    DARCY BURBAGEONCOLOGY CLINICAL NURSE, CHRISTIANA CARE HEALTH SYSTEM USA

    EVANDRO DE AZAMBUJA HEAD OF THE MEDICAL SUPPORT TEAM, JULES BORDET INSTITUTE BELGIUM

    FABRICE ANDREMEDICAL ONCOLOGIST, INSTITUT GUSTAVE ROUSSY FRANCE

    INTERNATIONAL SPEAKERS

  • 5

    GIUSEPPE CURIGLIANO ASSOCIATE PROFESSOR, UNIVERSITY OF MILANO ITALY

    IAN KROP ASSOCIATE CHIEF DIVISION OF BREAST ONCOLOGY, DANA FARBER CANCER INSTITUTE USA

    JAVIER CORTES MEDICAL ONCOLOGIST, HOSPITAL UNIVERSITARIO RAMÓN Y CAJAL SPAIN

    LISA CAREY PROFESSOR, NORTH CAROLINA CANCER HOSPITAL USA

    MONICA MORROW SURGICAL ONCOLOGIST, MEMORIAL SLOAN KETTERING CANCER CENTER USA

    NICHOLAS TURNER CONSULTANT MEDICAL ONCOLOGIST, THE INSTITUTE OF CANCER RESEARCH UNITED KINGDOM

  • 6

    PETER FASCHING ASSOCIATE PROFESSOR, UNIVERSITY HOSPITAL ERLANGEN AND COMPREHENSIVE CANCER CENTER GERMANY

    PHILIP POORTMANS PROFESSOR, CURIE INSTITUTE BELGIUM

    SANDRA SWAIN ASSOCIATE DEAN FOR RESEARCH DEVELOPMENT, PROFESSOR OF MEDICINE, GEORGETOWN UNIVERSITY MEDICAL CENTER USA

    SHAHEENAH DAWOOD MEDICAL ONCOLOGIST, MEDICLINIC CITY HOSPITAL UNITED ARAB EMIRATES

    STEPHEN JOHNSTON PROFESSOR, THE ROYAL MARSDEN NHS FOUNDATION TRUST UNITED KINGDOM

  • 7

    REGIONAL SPEAKERS

    AMY CHOW ASSOCIATE PROFESSOR, DEPARTMENT OF SOCIAL WORK AND SOCIAL ADMINISTRATION - THE UNIVERSITY OF HONG KONG HONG KONG

    JANICE TSANG SPECIALIST IN MEDICAL ONCOLOGY, LI KA SHING FACULTY OF MEDICINE, THE UNIVERSITY OF HONG KONG HONG KONG

    JYOTI BAJPAI MEDICAL ONCOLOGIST, TATA MEMORIAL HOSPITAL INDIA

    LU YEN SHEN CLINICAL PROFESSOR, NATIONAL TAIWAN UNIVERSITY TAIWAN

    SEOCK-AH IM MEDICAL ONCOLOGIST, SEOUL NATIONAL UNIVERSITY COLLEGE OF MEDICINE SOUTH KOREA

    SHERENE LOI MEDICAL ONCOLOGIST, PETER MACCALLUM CANCER CENTRE AUSTRALIA

  • 8

    SHOM GOEL CONSULTANT MEDICAL ONCOLOGIST, PETER MACCALLUM CANCER CENTRE AUSTRALIA

    SHONA NAG CONSULTANT MEDICAL ONCOLOGIST, DIRECTOR OF ONCOLOGY, SAHYADRI GROUP OF HOSPITALS INDIA

    VIROTE SRIURANPONG CHIEF, MEDICAL ONCOLOGY UNIT, CHULALONGKORN UNIVERSITY THAILAND

    YEON HEE PARK MEDICAL ONCOLOGIST, SUNGKYUNKWAN UNIVERSITY SCHOOL OF MEDICINE SOUTH KOREA

  • 9

    LOCAL SPEAKERS

    ELAINE LIM SENIOR CONSULTANT, NATIONAL CANCER CENTRE SINGAPORE (NCCS) SINGAPORE

    IAIN TAN MEDICAL ONCOLOGIST, NATIONAL CANCER CENTRE SINGAPORE (NCCS) SINGAPORE

    JACK CHAN CONSULTANT, NATIONAL CANCER CENTRE SINGAPORE (NCCS) SINGAPORE

    JOLINE LIM CONSULTANT, DEPARTMENT OF HAEMATOLOGY-ONCOLOGY, NATIONAL UNIVERSITY CANCER INSTITUTE SINGAPORE

    LEE SOO CHIN MEDICAL ONCOLOGIST, NATIONAL UNIVERSITY CANCER INSTITUTE SINGAPORE

    MAY LENG MABEL TAN ADVANCED PRACTICE NURSE, NATIONAL CANCER CENTRE SINGAPORE (NCCS)SINGAPORE

  • 10

    REBECCA DENT SENIOR CONSULTANT, NATIONAL CANCER CENTRE SINGAPORE (NCCS SINGAPORE

    SAMUEL OW CONSULTANT MEDICAL ONCOLOGIST, NATIONAL UNIVERSITY CANCER INSTITUTESINGAPORE

    TAN PUAY HOON MEDICAL ONCOLOGIST, SINGAPORE GENERAL HOSPITAL SINGAPORE

    TIRA TAN CONSULTANT, DIVISION OF MEDICAL ONCOLOGY, NATIONAL CANCER CENTRE SINGAPORE (NCCS) SINGAPORE

    VERONIQUE TAN HEAD & SENIOR CONSULTANT BREAST SURGERY NATIONAL CANCER CENTRE SINGAPORE (NCCS) SINGAPORE

    WONG NAN SOON MEDICAL ONCOLOGIST, GLENEAGLES HOSPITAL SINGAPORE

  • 11

    YAP YOON SIM SENIOR CONSULTANT, NATIONAL CANCER CENTRE SINGAPORE (NCCS) SINGAPORE

    APBCS.ORG

  • 12

    SINGAPORE TIME

    DAY ONE8th JANUARY, 2021

    DAY TWO9th JANUARY, 2021

    DAY THREE10th JANUARY, 2021

    08:00 GOING LIVE

    08:30

    Oncology Nursing Session

    09:30

    10:30

    11:30

    12:30

    13:00

    13:30

    14:00

    14:00

    14:30

    15:30 GOING LIVE GOING LIVE GOING LIVE

    16:00

    Best of San Antonio Breast Cancer

    Symposium

    9th Asia-Pacific Breast Cancer

    Summit

    Day 1

    9th Asia-Pacific Breast Cancer

    Summit

    Day 2

    16:30

    17:00

    17:30

    18:00 GOING LIVE

    18:30

    6th Singapore Breast Oncoplastic Surgery Symposium

    (SBOSS)

    19:00

    19:30

    20:00

    20:30

    21:00

    21:30

    22:00

    22:30

    PROGRAM AT A GLANCE

    12

  • 13

    BEST OF SAN ANTONIO BREAST CANCER SYMPOSIUM PROGRAM

    15:30 – 15:40 Topics Presented By: LIM GEOK HOON, SINGAPORE

    Radioactive Iodine Seed placement in the Axilla with Sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer: results of the prospective multicenter RISAS trial

    15.40 – 15.45 Q & A

    15.45 – 15.55 Topics Presented By: FAYE LIM, SINGAPORE

    Prime 2 randomised trial (postoperative radiotherapy in minimum-risk elderly): wide local excision and adjuvant hormonal therapy +/- whole breast irradiation in women =/> 65 years with early invasive breast cancer:10 year results

    A randomized phase III study of radiation doses and fractionation schedules in non-low risk ductal carcinoma in situ (DCIS) of the breast (BIG 3-07/TROG 07.01)

    15.55 – 16.00 Q & A

    16.00 – 16.20 Topics Presented By: SHAHEENAH DAWOOD, UAE

    Final invasive disease-free survival analysis of monarchE: abemaciclib combined with adjuvant endocrine therapy for high risk early breast cancer

    Phase III study of palbociclib combined with endocrine therapy (ET) in patients with hormone-receptor-positive (HR+), HER2-negative primary breast cancer and with high relapse risk after neoadjuvant chemotherapy (NACT): First results from PENELOPE-B

    12 year results of anastrozole versus tamoxifen for the prevention of breast cancer in postmenopausal women with locally excised ductal carcinoma in-situ

    16.20 – 16.25 Q & A

    16.25 – 16.35 Topics Presented By: TIRA TAN, SINGAPORE

    Neoadjuvant nab-paclitaxel weekly versus dose-dense paclitaxel followed by dose-dense EC in high risk HR+/HER2- early BC by: results from the neoadjuvant part of ADAPT HR+/HER2- trial

    Correlative studies of the Breast Cancer Index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine benefit: a Trans-aTTom Study

    16.35 – 16.40 Q & A

    Friday, 8th January 2021

    15.30 - 17.40 Singapore Time

  • 14

    16.40 – 17.05 Topics Presented By: WONG NAN SOON, SINGAPORE

    Adjuvant trial randomized ER+ patients who had a Recurrence Score < 25 and 1-3 positive nodes to endocrine therapy (ET) versus ET + chemotherapy.

    Development and validation of a tool integrating the 21-gene recurrence score and clinicopathlogic features to individualize prognosis for distant recurrence and prediction of absolute chemotherapy benefit in early breast cancer

    How low is low risk: MINDACT updated outcome and treatment benefit in patients considered clinical low risk and stratified by genomic signature, age and nodal status

    Endocrine therapy alone in patients with intermediate or high-risk luminal early breast cancer (0-3 lymph nodes), Recurrence Score

  • 15

    ONCOLOGY NURSING SESSION

    Saturday, 9th January 2021

    8.30 - 13.00 Hrs Singapore Time

    08:30 – 08:35 Welcome MABEL TAN MAY LENG

    DNP, RN, ONC, NATIONAL CANCER CENTRE SINGAPORE

    08:35 – 09:35 Overview of Breast Cancer Treatment DARCY BURBAGE

    DNP, RN, AOCN, CBCN, CHRISTIANA CARE HEALTH SYSTEM, NEWARK, DELAWARE, USA

    09:35 – 10:05 Management of Breast Cancer Surgical Side Effects DARCY BURBAGE

    DNP, RN, AOCN, CBCN, CHRISTIANA CARE HEALTH SYSTEM, NEWARK, DELAWARE, USA

    10:05 – 10:15 Break

    10:15 – 11:15 Psychosocial Challenges and Management of Breast Cancer and Treatments AMY CHOW

    PHD, RSW, FT, THE UNIVERSITY OF HONG KONG, HONG KONG

    11:15 – 11:45 Small Group Case Studies Discussion Activity in Breakout Rooms FACILITATORS

    (10 GROUPS)

    11:45 – 12:55 Sharing by Small Group Facilitators or Representatives Comments by Speakers and Participants

    MABEL TAN MAY LENG SINGAPORE

    DARCY BURBAGE USA

    AMY CHOW HONG KONG

    12:55 – 13:00 Conclusion & Announcements MABEL TAN MAY LENG

    SINGAPORE

  • 16

    APBCS AGENGA – DAY 1

    15:50 – 15:55 Opening Remarks APBCS 2021 COMMITTEE

    15:55 – 16:00 Session Introduction - YEON HEE PARK, SOUTH KOREA (Supported by MSD)

    16:00 – 16:20 Advances of Immunotherapy in Neoadjuvant TNBCJAVIER CORTES, SPAIN

    16:20 – 16:40 An Asian Perspective with Case studiesYEON HEE PARK, SOUTH KOREA

    16:40 – 16:45 Q & A

    SESSION 1: ER + Early Breast Cancer Chairperson: VERONIQUE TAN, SINGAPORE | YAP YOON SIM, SINGAPORE

    16:45 – 17:05 Should all ER-pos Patients Receive 10 years of Endocrine Therapy?STEPHEN JOHNSTON, UK

    17:05 – 17:25 Is it time to adopt CDK inhibitors in adjuvant setting? Critical evaluation of the literatureEVANDRO DE AZAMBUJA, BELGIUM

    17:25 – 17:45 Q & A

    SESSION 2: Early Breast Cancer Chairperson: ELAINE LIM, SINGAPORE | SHAHEENAH DAWOOD, UAE

    17:45 – 18:05 Special Issues in Young Women with Early Breast Cancer JYOTI BAJPAI, INDIA

    18:05 – 18:25 Personalised breast RT - Are we there yet? PHILIP POORTMANS, BELGIUM

    18:25 – 18:45 What’s New in Surgical Management of the Axilla? MONICA MORROW, USA

    Q & A

    Saturday, 9th January 2021

    15.50 - 21.15 Hrs Singapore Time

  • 17

    AstraZeneca Symposium 1 - Chairperson: JOLINE LIM, SINGAPORE

    18:45 – 18:50 Welcome and Introductions JOLINE LIM, SINGAPORE

    18:50 – 19:05 Evolving role of ADCs in the management of Her2+ mBC IAN KROP, USA

    19:05 – 19:20 Optimizing treatment outcomes while treating Her2+ mBC patients with ADCs IAN KROP, USA

    19:20 - 19:30 Q & A and live discussion

    SESSION 3: Neo Adjuvant Therapy Chairperson: SOO CHIN LEE, SINGAPORE | REBECCA DENT, SINGAPORE

    19:30 – 19:50 Tailoring Neoadjuvant / Adjuvant HER2+ Therapy in Breast Cancer PETER FASCHING, GERMANY

    19:50 – 20:10 Tailoring/Neoadjuvant/Adjuvant TNBC Therapy in Breast Cancer LISA CAREY, USA

    20:10 – 20:25 Q & A

    Roche Symposium

    An Emerging Paradigm in HER2-positive Breast Cancer Treatment

    Chairperson: VIROTE SRIURANPONG, THAILAND

    20:25 - 20:50 Advancing patient care in HER2-positive breast cancer SANDRA SWAIN, USA

    20:50 - 21:05 Flexible Care: Moving Beyond the Hospital to the Community LEE SOO CHIN, SINGAPORE

    21:05 - 21:10 Q & A and Live Interaction

    21:10 Closing RemarkAPBCS 2021 COMMITTEE

  • 18

    15:55 – 16:00 Opening Remarks APBCS 2021 COMMITTEE

    Novartis Symposium - Chairperson: LEE SOO CHIN, SINGAPORE

    16:00 – 16:15 Transforming Treatment in Pre-menopausal HR+ HER20 ABC: Biological Differences and the role of CDK4/6i LU YEN SHEN, TAIWAN

    16:15 – 16:30 Personalized Approach to Treatment: Practical Recommendations in Optimizing Treatment for HR+ HER-2 ABC Patients with PIK3CA Mutation LU YEN SHEN, TAIWAN

    16:30 – 16:45 Q & A and live discussion

    SESSION 4: Tumor Biology and AssessmentChairperson: TIRA TAN, SINGAPORE | IAIN TAN, SINGAPORE

    16:45 – 17:05 Liquid BiopsiesNICHOLAS TURNER, UK

    17:05 – 17:25 Molecular Profiling for Metastatic Breast Ca- When, How and Why?FABRICE ANDRE, FRANCE

    17:25 – 17:45 What’s on the horizon for new drug development?GIUSEPPE CURIGLIANO, ITALY

    17:45 – 17:50 Q & A

    SESSION 5: Molecular Tumor BoardChairperson: SHAHEENAH DAWOOD, UAE | PAUL MAINWARING, AUSTRALIA

    17:50 – 18:30 Tumor Board 1

    PANELIST: GIUSEPPE CURLIGLIANO, ITALY | SEOCK-AH IM, SOUTH KOREA | SHAHEENAH DAWOOD, UAE | SAMUEL OW, SINGAPORE

    Pfizer Symposium - Chairperson: SAMUEL OW, SINGAPORE

    18:30 – 18:35 Welcome and Introductions SAMUEL OW, SINGAPORE

    18:35 – 18:55 Management of HR+ HER2- mBC: From Clinical Evidence to Real-World Experience JANICE TSANG, HONG KONG

    APBCS AGENGA – DAY 2

    Sunday, 10th January 2021

    15.55 - 21.45 Hrs Singapore Time

  • 19

    18:55 – 19:10 Case Presentation SHONA NAG, INDIA

    19:10 – 19:15 Q & A and live discussion

    SESSION 6: Advances in Clinical Management of Metastatic Breast CancerChairperson: JOLINE LIM, SINGAPORE | JACK CHAN, SINGAPORE

    19:15 – 19:35 Novel approaches to HER2 + metastatic disease? Where do novel agents fit it? SEOCK-AH IM, SOUTH KOREA

    19:35 – 19:55 Beyond first line CDK inhibition ER + MBC? SHOM GOEL, AUSTRALIA

    19:55 – 20:15 New Therapies in TNBC ADITYA BARDIA, USA

    AstraZeneca Symposium 2 - Chairperson: TIRA TAN, SINGAPORE

    20:15 – 20:20 Welcome and Introductions TIRA TAN, SINGAPORE

    20:20 – 20:45 Orchestrating the Sequencing strategies for HR+/Her2- mBC: Lessons learnt in the decade ADAM M. BRUFSKY, USA

    20:45 – 21:00 Q & A and live discussion

    SESSION 7: Interrogating the Immune System in Breast Cancer Chairperson: SHERENE LOI, AUSTRALIA | REBECCA DENT, SINGAPORE

    21:00 – 21:15 Pathologist’s view on how to best to measure PD-L1? TAN PUAY HOON, SINGAPORE

    21:15 – 21:30 New Biomarkers and Models Systems to Discern Sensitivity to Immune Checkpoint Inhibition CHARLES PEROU, USA

    21:30 – 21:45 What biomarkers do I need to order for my patient with metastatic TNBC and when? Novel therapies on the horizon for TNBC SHERENE LOI, AUSTRALIA

    21:45 Closing RemarkAPBCS 2021 COMMITTEE

  • 2

    Therapeutic indications

    Tecentriq® (Atezolizumab) – Abbreviated Prescribing Information 3

    Before prescribing TECENTRIQ®, please consult the full local prescribing information by visiting

    www.roche.com.sg/en/pharma/tecentriq.html or by scanning the following QR code.

    Published by Roche Singapore Pte Ltd 1 Paya Lebar Link, # 09-03 PLQ 1 Paya Lebar Quarter, Singapore 408533 Tel: +65 6735 0550 | Fax: +65 6737 5216

    For HCPs only

    M-SG-00000136-10-2020

    Recommended by International guidelines 1

    TECENTRIQ + nab-paclitaxel: The only cancer immunotherapy in PD-L1 + 1L mTNBC that demonstrated a clinically meaningful Overall Survival improvement

    of 7.5 months2

    Test your 1L mTNBC patients for PD-L1 status now

    TECENTRIQ® + NAB-PACLITAXEL

    KEEP PATIENTS WITH TNBC CONNECTED TO LIFE

    Updated IMpassion 130 final OS data

    Non Small Cell Lung Cancer (NSCLC): • TECENTRIQ®, in combination with Avastin, paclitaxel and carboplatin, is indicated for the treatment of patients with metastatic non-squamous NSCLC who had not received prior chemotherapy. • TECENTRIQ® is indicated for the treatment of patients with metastatic NSCLC who have disease progression during or following platinum-containing chemotherapy. • Patients with EGFR or ALK genomic tumor aberrations should have disease progression on approved therapy for these aberrations prior to receiving TECENTRIQ®. • TECENTRIQ®, in combination with nab-paclitaxel and carboplatin is indicated for first line treatment of patients with metastatic non squamous NSCLC who do not have EGFR or ALK genomic tumor aberrations. Small Cell Lung Cancer (SCLC): • TECENTRIQ® in combination with carboplatin and etoposide, is indicated for the first line treatment of patients with extensive-stage small cell lung cancer (ES-SCLC). Triple Negative Breast Cancer (TNBC): • TECENTRIQ® in combination with nab-paclitaxel, is indicated for the treatment of patients with unresectable locally advanced or metastatic TNBC whose tumors have PD-L1 expression >1%, and who have not received prior chemotherapy for metastatic disease. Hepatocellular carcinoma (HCC): • TECENTRIQ® in combination with Avastin, is indicated for the treatment of patients with unresectable HCC who have not received prior systemic therapy.

    Dosage and method of administration• TECENTRIQ® must be administered as an intravenous infusion under the supervision of a qualified healthcare professional. Do not administer as an IV push or bolus and do not co-administer other medicinal products through the same infusion line. The initial dose of TECENTRIQ® must be administered over 60 minutes. If the first infusion is tolerated, all subsequent infusions may be administered over 30 minutes.

    • The recommended dose of TECENTRIQ® in monotherapy or combination therapy is: 840 mg administered by IV infusion every 2 weeks, or 1200 mg administered by IV infusion every 3 weeks, or 1680 mg administered by IV infusion every 4 weeks.

    • TECENTRIQ® combination therapy: For the use of TECENTRIQ® in combination therapy, please also refer to the full prescribing information for the combination product. TECENTRIQ® should be administered prior to the combination therapy if given on the same day. 1L non-squamous NSCLC TECENTRIQ® in combination with Avastin, paclitaxel, and carboplatin During the induction phase, TECENTRIQ® is administered according to its dosing schedules by intravenous (IV) infusion, and Avastin, paclitaxel, and carboplatin are administered every 3 weeks for four or six cycles. The induction phase is followed by a maintenance phase without chemotherapy in which TECENTRIQ® is administered according to its dosing schedules by IV infusion, and Avastin is administered every 3 weeks. TECENTRIQ® in combination with nab-paclitaxel and carboplatin During the induction phase, TECENTRIQ® is administered according to its dosing schedules by IV infusion, and nab-paclitaxel and carboplatin are administered every 3 weeks for four or six cycles. For each 21-day cycle, nab-paclitaxel and carboplatin are administered on day 1. In addition, nab-paclitaxel is administered on days 8 and 15. The induction phase is followed by a maintenance phase without chemotherapy in which TECENTRIQ® is administered according to its dosing schedule. 1L ES-SCLC TECENTRIQ® in combination with carboplatin and etoposide During the induction phase, TECENTRIQ® is administered according to its dosing schedules by IV infusion, and carboplatin and etoposide are administered by IV infusion every three weeks for four cycles. Carboplatin and etoposide are administered on day 1 of each cycle, and etoposide is also administered on days 2 and 3. The induction phaste is followed by a maintenance phase without chemotherapy in which TECENTRIQ® is administered according to its dosing schedules by IV infusion. 1L TNBC TECENTRIQ® in combination with nab-paclitaxel. TECENTRIQ® is administered according to its dosing schedules by IV infusion and 100 mg/m2 nab-paclitaxel is administered on days 1, 8 and 15 during each 28-day cycle. Patients should be selected for treatment based on the tumor expression of PD-L1 confirmed by a validated test (see section 3.1.2 Clinical / Efficacy Studies). HCC TECENTRIQ® in combination with Avastin. TECENTRIQ® is administered according to its dosing schedules by IV infusion, and Avastin 15 mg/kg is administered every 3 weeks.

    The safety and efficacy of alternating or switching between TECENTRIQ® and products that are biosimilar but not deemed interchangeable to TECENTRIQ® has not been established. Therefore, the benefit/risk of alternating or switching needs to be carefully considered. Safety reporting for potential undesirable effects: Please report any adverse events to the local Roche Adverse Event email at [email protected] or call (65) 6735 0550. This will enable Roche to better understand the safety of TECENTRIQ®, and to provide appropriate information to Health Authorities, Healthcare Providers and patients.

    References: 1. Gradishar, W. (2020, July 15). NCCN Clinical Practice Guidelines in Oncology - Breast Cancer. Retrieved 2020, from https://www2.tri-kobe.org/nccn/guideline/breast/english/breast.pdf. 2. Emens, LA, et al. IMpassion130: Final OS analysis from the pivotal phase III study of atezolizumab and nab-paclitaxel vs placebo and nab-paclitaxel in previously untreated locally advanced or metastatic triple-negative breast cancer. Annals of Oncology (2020) 31 (S4): S1148. doi.org/10.1016/j.annonc.2020.08.2244. 3.TECENTRIQ® Prescribing Information August 2020

  • THE 9TH ASIA-PACIFIC BREAST CANCER VIRTUAL SUMMIT INDUSTRY SATELLITE SYMPOSIUMSponsored by Pfizer Oncology

    Management of HR+ HER2- mBC:From Clinical Evidence to Real-World Experience

    Join regional thought-leaders in exploring key advances in the field of HR+ HER2- mBC, with a focus on real-world

    data of CDK4/6 inhibitors, as well as how to eectively navigate the mBC patient journey in Asia.

    10 January 2021(Sunday)

    18:30–19:15 (GMT+8)

    INVITATION

    Pfizer Private Limited80 Pasir Panjang Road, #16-81/82, Mapletree Business City, Singapore 117372Tel: (65) 6403 8888 | Fax: (65) 6403 8868 | www.pfizer.com.sg

    This symposium may contain information about investigational product(s)/indication(s) which are yet to be approved in your country. For healthcare professionals only. More information is available upon request.

    PP-IBR-SGP-0066/05JAN2021

    A G E N D A

    Duration

    5 mins

    20 mins

    15 mins

    5 mins

    Faculty

    Dr Samuel Ow, Singapore

    Dr Janice Tsang, Hong Kong

    Dr Shona Nag, India

    Dr Samuel Ow, Singapore

    Topic

    Introduction

    Management of HR+ HER2- mBC: From Clinical Evidence to Real-World Experience

    Case Presentation

    Q&A

    S P E A K E R S

    Dr Samuel Ow Consultant

    National University Cancer Institute Singapore

    Dr Janice Tsang Honorary Clinical Assistant Professor

    The University of Hong KongHong Kong

    Dr Shona NagDirector of Oncology ServicesSahyadri Group of Hospitals

    Pune, India

    C H A I R P E R S O N

    JOIN OUR SYMPOSIUM VISIT OUR PROFILE

  • LIFE

    JOB NO.: 122983

    For Healthcare Professionals Only. Please scan this QR code or visit https://www.novartis.com.sg/product-list/kisqali to access the full prescribing information

    Novartis (Singapore) Pte Ltd20 Pasir Panjang Road, #10-25/28 Mapletree Business City, Singapore 117439Phone: +65 6722 6010 • Fax: +65 6323 4335 • www.novartis.comSG1909734699

  • PLATINUM SPONSORS

    SILVER SPONSOR E-PARTNERS

    MAIN SPONSORS

    Inventing for life

  • 24

    APBCS.ORG

    INDEX® Conferences & Exhibitions Organization Est.P.O. Box: 13636 | Dubai-UAE | INDEX Holding Headquarters Road # D-62 | Opposite Nad Al HamarTel: +971 4 5208888 | Fax: +971 4 3384193 | Email: [email protected]

    SEE YOU AGAININ

    2022