6th International Workshop on the Treatment of Hepatic and Lung Metastases and Peritoneal Carcinomatosis of Colorectal CarcinomaNovember 16th and 17th, 2017Venue: Hotel NH Barcelona ConstanzaBarcelona, Spain

Organised by:

Oncology and Hematology ServiceUnit of Hepato- Biliary and Pancreatic SurgeryThoracic Surgery Service

Hospital Universitari MútuaTerrassa (Terrassa, Barcelona, Spain)

We welcome you to the SIXTH EDITION of the INTERNATIONAL WORKSHOP ON THE TREATMENT OF HEPATIC AND LUNG METASTASES AND PERITONEAL CARCINOMATOSIS OF COLORECTAL CARCINOMA that will take place in Barcelona (Spain) on the 16th and 17th November, 2017

For the first time we have included Peritoneal Carcinomatosis because of its clinical relevance and challenging management.

The Workshop is focusing on the state-of-the art of the multimodal management of these three metastasic sites.

We invite you to actively participate In the scientific programme.

We look forward to an interesting and productive meeting and hope to see you in Barcelona!

Lluis Cirera Esteban Cugat and Ramón Rami-PortaWorkshop’s Chairman Workshop’s Vice-Chairmen

COMMITTEE

Workshop coordinators

Chairman: Lluis CireraVice-Chairmen: Esteban Cugat, Ramón Rami-Porta

Organizing committee

José BeldaCarla BellidoSergi CallEsther CasadoLluis CireraEsteban CugatSalvadora DelgadoJulen FernándezMaribel García-DomingoJosé Manuel GonzálezEric HerreroJosé Ángel de MarcosMarta ParairaRamón Rami-PortaMontserrat Ysamat

Scientific committee

Rene AdamSergi CallLluis CireraEsteban CugatJesús García-FoncillasRamón Rami-PortaPaul van SchilPaul H. Sugarbaker

PROGRAMME

Thursday, November 16th, 2017

10:00-10:45

11:00-11:30

11:30-14:00

14:00-15:15

14:15-20:00

15:15-16:40

Registration

Welcome and introductionRosa Asbert. Medical Director. Hospital Universitari MútuaTerrassa. Terrassa. BarcelonaLluis Cirera. Oncology and Hematology Service. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud Barcelona

Sponsored symposia

Lunch

Poster display

INTERACTIVE SESSION 1: Clinical case with multidisciplinary team discussion. Patient with liver metastases and peritoneal carcinomatosis

Moderators: Esteban Cugat. Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. BarcelonaLluis Cirera. Oncology and Hematology Service. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Clinical case presentationComments: Pedro Barrios. Oncology Surgery Service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí

Surgery of Liver Metastases: How far should we go?René Adam. Oncosurgical Unit. Hepatobiliary Center. University Paris Sud. Hôpital Paul-Brousse. Paris

Radiological disappearance of hepatic metastases after systemic treatment: What can we do?Miguel Ángel Gómez Bravo. Surgery and Trasplantation Unit. Hospital Universitario Virgen del Rocio. Sevilla

Minimal residual disease: a new paradigmRamón Salazar. Medical Oncology. Institut Català de Oncologia. Barcelona

Discussion

15:15-15:45

15:45-16:00

16:00-16:15

16:15-16:30

16:30-16:40

LECTURE

Introduction: Eric Herrero. Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. BarcelonaFernando Pardo. Hepatobiliary Surgery Service. Clínica Universitaria de Navarra. Pamplona. Navarra

Coffee Break

LIVER METASTASES

Moderators: Maribel García Domingo. Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. -Centro Médico Teknon. Grupo Quirónsalud. BarcelonaMiguel Ángel Gómez Bravo. Surgery and Trasplantation Unit. Hospital Universitario Virgen del Rocio. Sevilla

LECTURE

Introduction: Marta Paraira. Radiodiagnostic Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Staged hepatectomy: to rush with ALPPS or to wait with conventional two-stage? René Adam. Oncosurgical Unit. Hepatobiliary Center. University Paris Sud. Hôpital Paul-Brousse. Paris

Questions

16:40-17:00

17:00-17:10

16:40-17:10

17:10-17:40

17:40-18:50

18:50-19:30

Benefits of laparoscopic liver resectionRubén Ciria. Surgery Service. University Hospital Reina Sofia. Córdoba

Metastases resection after Aflibercept in second-line chemotherapyAndrés Muñoz. Oncology Service. Hospital Gregorio Marañón. Madrid

Liver surgery before primary tumour resectionFernando Pardo. Hepatobiliary Surgery Service. Clínica Universitaria de Navarra. Pamplona. Navarra

Discussion

17:40-18:10

18:10-18:25

18:25-18:40

18:40-18:50

Liver imaging: MRI or CT?Judith Camps. Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Genomics and radiogenomicsLuis Marti-Bonmati. Radiology Service. Hospital Universitario y Politécnico La Fe. Valencia

Questions

18:50-19:00

19:00-19:20

19:20-19:30

Friday, November 17th, 2017

08:00-08:55

08:55-09:25

INTERACTIVE SESSION 2: Clinical case with multidisciplinary team discussion. Patient with lung and liver metastases

Moderators: Mireia Serra. Thoracic Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona Julen Fernández. Oncology and Hematology Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

LECTURE

Introduction: Ramón Rami-Porta. Thoracic Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. BarcelonaLaureano Molins. Thoracic Surgery Service, Hospital Clínic, Hospital Universitari Sagrat Cor. Barcelona -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Clinical case presentation

Biomarkers for selection of chemotherapyDavid Paez. Medical Oncology Service. Hospital de la Santa Creu i Sant Pau. Barcelona

Discussion

08:00-08:30

08:30-08:45

08:45-08:55

Surgery and ablative techniques for treatment of lung metastases of colorectal cancer: past, present and futureTom Treasure. Clinical Operational Research Unit. University College London. London Questions

08:55-09:15

09:15-09:25

09:25-09:45

09:45-10:55

10:55-11:25

Coffee Break

LUNG METASTASES

Moderators: Sergi Call. Thoracic Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. BarcelonaRamón Rami-Porta. Thoracic Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa

LECTURE

Introduction: Pedro Barrios. Oncology surgery service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí

Surgery for lung metastases of colorectal carcinoma. Do we believe in what we do? Results from the Survey of the Spanish Society of Thoracic SurgeryRaúl Embún. Department of Thoracic Surgery. Hospital Universitario Miguel Servet. Zaragoza

Role of major lung resections in the surgical treatment of lung metastases of colorectal carcinomaJorge Hernández. Thoracic Surgery Unit. Hospital Universitari del Sagrat Cor. Barcelona

Technical aspects of laser resection of lung metastasesSebastian Wiesemann. Department of Thoracic Surgery. University Medical Center Freiburg. Freiburg

Isolated lung perfusion and related techniques for treatment of pulmonary metastasis. Is survival really improved?Paul Van Schil. Department of Thoracic and Vascular Surgery. University Hospital of Antwerp. Edegem

Discussion

09:45-10:00

10:00-10:15

10:15-10:30

10:30-10:45

10:45-10:55

Management for peritoneal metastases: an updatePaul H. Sugarbaker. Medical Director. Center for Gastrointestinal Malignancies Chief. Program in Peritoneal Surface Oncology. MedStar Washington Hospital Center. Washington

Questions

10:55-11:15

11:15-11:25

11:25-13:05

13:05-13:35

INTERACTIVE SESSION 3: Clinical case with multidisciplinary team discussion. Patient with peritoneal carcinomatosis

Moderators: Esther Casado. Oncology Service. Althaia. Xarxa Assistencial de Manresa. Manresa. BarcelonaMaría Isabel Ramos. Oncology Surgery Service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí

LECTURE

Introduction: Lluis Cirera. Oncology and Hematology. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Clinical case presentation

Pathophysiology of colorectal peritoneal carcinomatosisPaul H. Sugarbaker. Medical Director. Center for Gastrointestinal Malignancies Chief. Program in Peritoneal Surface Oncology. MedStar Washington Hospital Center. Washington Diagnostic imaging in peritoneal carcinomatosisNadine Romera. Radiology Service. Hospital Quirónsalud. Barcelona -Centro Médico Teknon. Grupo Quirónsalud. Barcelona Immune chekpoints and immunotherapy for mCRCFerrán Losa. Oncology Surgery Service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí Outcomes in the care of peritoneal carcinomatosis in the Catalonian public health systemJosé María Borrás. University of Barcelona and Catalonian Cancer Strategy Discussion

11:25-11:55

11:55-12:10

12:10-12:25

12:25-12:40

12:40-12:55

12:55-13:05

Sidedness or molecular profileJesús García-Foncillas. Oncology Department. Fundación Jiménez Díaz. Madrid

Questions

13:05-13:25

13:25-13:35

13:35-14:10 POSTER SESSION

1 | Increase in splenic volume predicts hepatic injury in patients with colorrectal liver metastases treated with chemotherapyPatricia Saez Carlin, Alejandra García Botella, Luis Díez Valladares, Ramiro Méndez Fernández, Luis Ortega Medina, Antonio Torres GarcíaHospital Clínico San Carlos, Madrid. Spain

2 | CD133 + cell infusion in patients with colorectal liver metastases going to be submitted to a major liver resectionAlejandra García Botella, Patricia Sáez Carlin, Luis Ignacio Díez Valladares, Rocio Avellana, Luis Ortega Medina, Ramiro Méndez Fernández, Javier Armijo, Antonio Torres GarcíaHospital Clínico San Carlos, Madrid. Spain

3 | Oncological strategies in rectal cancer with liver metastases Lucas Casalduero García, Alberto Carabias Hernández, Carlos José Gamo Albero, Paloma Sanz Muñoz, Alvaro Sobrino Grande, Ana Serantes, Miguel Ángel Delgado, Jose María Jover NavalónHospital Universitario de Getafe, España

4 | Utility of 3D printing model reconstruction in complex hepatic surgery. Our experienceLuque Molina, A1; Alcalá, L2; López León, M3; López Martínez, C1; Jodral, T1; Luna Alcalá2, A; López Cillero, P3

1 Unidad de Cirugía HBP HSJDD Córdoba; 2 Servicio Radiología HSJDD Córdoba; 3 Facultad de Medicina Universidad de Córdoba

5 | Oligometastasic colorectal cancer (CRC) lung metastases treated with stereotactic body radiotherapy (SBRT), experience of “Hospital Universitario Donostia”María Otaño1, M.Aránzazu Bujedo1, Ana Landa1, M.Ángeles Díaz1, Daniel Roura2, M.Eguzki Iraolagoitia2, Leyre González2, Julian Minguez2, Adelaida La Casta11 Medical Oncology, Hospital Universitario Donostia; 2 Radiotherapic Oncology, Hospital Universitario Donostia. San Sebastian, Spain

6 | Wound recurrence: a rare event after colorectal hepatic metastases surgeryA. Landa Magdalena; A. La Casta Muñoa; M. Otaño Ariño; MA. Diaz Gallego; M. Alkorta ZuloagaHospital Universitario Donostia. San Sebastian. Spain

14:10-14:15

14:15-14:20

14:20

7 | Location of colorectal cancer as a prognosis factor and a predictor in our areaJose Carlos Benítez1 MD, Julen Fernandez1 MD, Carmen Ferrer2 MD, José Ángel de Marcos3 MD, Marta Paraira3 MD, Luis Cirera1 MD1 Department of Medical Oncology. Hospital Universitari Mutua Terrassa. Terrassa, University of Barcelona, Barcelona, Spain. 2 Department of Pathology. Hospital Universitari Mutua Terrassa. Terrassa, University of Barcelona, Barcelona, Spain. 3 Department of Radiology. Hospital Universitari Mutua Terrassa. Terrassa, University of Barcelona, Barcelona, Spain

BEST POSTER AWARD

Closing

LUNCH

René AdamOncosurgical Unit. Hepatobiliary Center. University Paris Sud. Hôpital Paul-Brousse. Paris

Rosa AsbertMedical Director. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Pedro BarriosOncology Surgery Service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí

José María BorrásUniversity of Barcelona and Catalonian Cancer Strategy

Sergi CallThoracic Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Judith CampsSurgery Service. Hospital MútuaTerrassa. Terrassa. Barcelona

Esther CasadoOncology Service. Althaia. Xarxa Assistencial de Manresa. Manresa. Barcelona

Lluis CireraOncology and Hematology Service. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Rubén CiriaSurgery Service. University Hospital Reina Sofia. Córdoba

Esteban CugatSurgery Service. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Raúl EmbúnDepartment of Thoracic Surger. Hospital Universitario Miguel Servet. Zaragoza

Julen FernándezOncology and Hematology Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Maribel García DomingoSurgery Service. Hospital Universitari MútuaTerrassa. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Jesús García-FoncillasOncology Department. Fundación Jiménez Díaz. Madrid

SPEAKERS AND CHAIRPERSONS

Miguel Ángel Gomez BravoSurgery and Trasplantation Unit. Hospital Universitario Virgen del Rocio. Sevilla

Jorge HernándezThoracic Surgery Unit. Hospital Universotari del Sagrat Cor. Barcelona

Eric HerreroSurgery Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Ferrán LosaOncology Surgery Service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí

Luis Marti-BonmatiRadiology Service. Hospital Universitario y Politécnico La Fe. Valencia

Laureano MolinsThoracic Surgery Service. Hospital Clínic. Hospital Universitari Sagrat Cor. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Andrés MuñozOncology Service. Hospital Gregorio Marañón. Madrid

David PaezMedical Oncology Service. Hospital de la Santa Creu i Sant Pau. Barcelona

Marta ParairaRadiodiagnostic Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

Fernando PardoHepatobiliary Surgery Service. Clínica Universitaria de Navarra. Pamplona. Navarra

Ramón Rami-PortaThoracic Surgery Service. Hospital Universitari MútuaTerrassa. Terrassa. Barcelona

María Isabel RamosOncology Surgery Service. Hospital Sant Joan Despí Moisès Broggi. Sant Joan Despí

Nadine RomeraRadiology Service. Hospital Quirónsalud. Terrassa -Centro Médico Teknon. Grupo Quirónsalud. Barcelona

Ramón SalazarMedical Oncology. Institut Català de Oncologia. Barcelona

Mireia SerraThoracic Surgery Service. Hospital MútuaTerrassa. Terrassa. Barcelona

Paul H. SugarbakerMedical Director. Center for Gastrointestinal Malignancies Chief. Program in Peritoneal Surface Oncology. MedStar Washington Hospital Center. Washington

Tom TreasureClinical Operational Research Unit. University College London. London

Paul Van SchilDepartment of Thoracic and Vascular Surgery. University Hospital of Antwerp. Edegem

Sebastian WiesemannDepartment of Thoracic Surgery. University Medical Center Freiburg. Freiburg

SPONSORED SYMPOSIUMS

11:30-12:15

12:20-13:05

13:10-13:55

Treatment intensity modulation based on Bevacizumab in mCRC patients candidates to surgerySponsored by Roche

Management of potentially resectable colorectal cancer liver metastasesCarles Pericay. Oncology Service. Hospital Parc Taulí. Sabadell

Oncologist’s point of viewVicente Alonso. Oncology Service. Hospital Miguel Servet. Zaragoza

Surgeon’s point of viewEsteban Cugat. Surgey Service. Hospital Universitari MútuaTerrassa. Terrassa

DiscussionCarles Pericay. Oncology Service. Hospital Parc Taulí. Sabadell

Therapeutical Strategies in Metastatic Colorectal Cancer (mCRC): The Value of PanitumumabSponsored by Amgen

Moderator: Dr. Alfredo Carrato. Hospital Ramon y Cajal. Madrid

Optimal sequencing in the treatment of mCRC: What’s the role of Panitumumab?Dr. Javier Gallego. Hospital General Universitario de Elche. Alicante

Does the sideness impact the treatment decision? New Panitumumab dataDra. Elena Elez. Hospital Vall d´Hebron. Barcelona

Seeing is believing: livermetsurvey & ADCCSponsored by Merck

René Adam. Oncosurgical Unit. Hepatobiliary Center. University Paris Sud. Hôpital Paul-Brousse. Paris

Jesús García-Foncillas. Oncology Department. Fundación Jiménez Díaz. Madrid

GENERAL INFORMATION

DATESNovember 16th and 17th, 2017. Barcelona, (Spain)

VENUEHotel NH Barcelona ConstanzaSt/ Deu i Mata, 69-99. 08029Barcelona (Spain)

TECHNICAL SECRETARIAT (REGISTRATION AND HOTEL RESERVATION)Acto ServeisC/ Bonaire, 708301 Mataró (Barcelona)Tel. 937 552 382Fax 937 552 383info@oncology-bcn.com

REGISTRATIONRegistration Fees

Before September 15th After September 16th andon-site registration

Members of:ACROSS, AEC, GEMCAD, SEOM, TTD, ESSO

650 € 690 €

Others 750 € 790 €

Residents 450 € 490 €

*VAT (21% IVA) is included*

ACOMMODATION

Double Room

Hotel NH Barcelona Constanza 192.39 €

CITY INFORMATIONBarcelona overlooks the Mediterranean and is located in a heavily populated area which is a hub of economic activity.

Barcelona enjoys a Mediterranean climate, with mild winters and warm summers.

It is a coastal city and has over four kilometres of urban beaches and large areas of nearby forest. Although it is a large city, it is easy to get around on public transport and on foot. You can reach any point in the city by metro, bus and taxi.

Barcelona is the capital of Catalonia. Its inhabitants are open and welcoming.

The people of Barcelona speak Catalan, their own language, and Spanish. Many of them also understand a little English and French

VisaSpain is part of the Schengen zone. This means that nationals from EU countries do not need a visa.

LenguageMost of Barcelona’s inhabitants are bilingual and speak Catalan, their own language, and Spanish.

ElectricityThe voltage in Spain is 220 volts, 50 Hz. The plug types are C and F.

ClimateThe city has a typically Mediterranean climate and enjoys pleasant temperatures all the year round.

CurrencyThe euro (€) is the official currency of the European Union and can be exchanged at savings banks and banks.

BanksBusiness hours differ between banks. Most banks are open from Monday to Friday from 08:15 to 14:15.

CustomsIn Barcelona mealtimes are usually a little later than the rest of Europe. The city’s shops have long opening hours.

Shopping in BarcelonaMonday to Saturday, from 09:30 to 13:30 and from 16:30 to 20:00. Most of the department stores do not close at mid-day.

ACADEMIC SUPPORT

EACCME® CREDITSEach participant can only receive the number of credits he/she is entitled to according to his/her actual participation at the event once he/she has completed the feedback form. Cf. criteria 9 and 23 of UEMS 2016.20.

In order to help you issue individual certificates to each participants, please find below the breakdown of ECMEC®s per day:

16.11.2017 - 3,0017.11.2017 - 5,00

The EACCME® awards ECMEC®s on the basis of 1 ECMEC® for one hour of CME with a maximum of 8 ECMEC®s per day. Cf. Chapter X of UEMS 2016.20.

SUPPORTED BY

SPONSORED BY

TECHNICAL SECRETARIAT

Acto ServeisC/ Bonaire, 708301 Mataró (Barcelona)Tel. 937 552 382Fax 937 552 383

www.oncology-bcn.com