D’Arcy CV,

Ryan C.N. D’Arcy, Ph.D.

PRIMARY APPOINTMENT AND ADDRESS

Program Leader/Site Manager, Research Officer Institute for Biodiagnostics (Atlantic)National Research Council (NRC-CNRC)Suite 3900, Neuroimaging Research Laboratory1796 Summer Street, Halifax InfirmaryHalifax, Nova Scotia Canada B3H 3A7Tel. (902) 473-1850 Fax. (902) 473-1851Email. Ryan.D'Arcy@nrc-cnrc.gc.caCitizenship: Canadian

EDUCATION

Doctor of Philosophy (1998-2002)Dalhousie University, Neuroscience Institute Psychology/Neuroscience Supervisors: Dr. John F. Connolly and Dr. Kazue Semba

Master of Science (1996-1998)Dalhousie University, Neuroscience Institute Experimental Neuropsychology Supervisor: Dr. John F. Connolly

Bachelor of Science with distinction (1990-1996)University of Victoria, Department of Psychology Neuropsychology Supervisor: Dr. Catherine A. Mateer

MAJOR INITIATIVES

$10M Neuroimaging Research Laboratory, QEII Health Sciences Centre (established 2003) Equipment: 4T MRI, 64-channel EEG (MR), and transcranial magnetic stimulation Partners: NRC, Capital Health, and Dalhousie University

$6M MR Micro-imaging Laboratory, IWK Health Centre (under construction) Equipment: 7T 89mm vertical bore and 3T 640mm horizontal bore MRI Partners: NRC, IWK Health Centre, and Dalhousie University

CONCURRENT APPOINTMENTS

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D’Arcy CV,

Scientific Staff (2004-present)Department of Diagnostic ImagingIWK Health CentreHalifax, NS

Affiliate Medical Staff (2003-present)Department of Diagnostic ImagingCapital HealthHalifax, NS

Assistant Professor (2003-present)Department of RadiologyFaculty of Medicine Dalhousie University Halifax, NS

Adjunct Professor (2002-present)Neuroscience Institute, Department of PsychologyFaculty of ScienceDalhousie UniversityHalifax, NS

WORK EXPERIENCE

Program Leader/Site Manager (2002-present) Institute for Biodiagnostics (Atlantic)Neuroimaging Research LaboratoryHalifax Infirmary, QEII Health Science CentreHalifax, NS

Research Officer (2002-present)MR Research and Development Group,Institute for Biodiagnostics,National Research Council Canada,Halifax, NS/Winnipeg, MB

Assistant Research Officer (2001-2002) Research Associate ProgramMR Technology Group,Institute for Biodiagnostics,National Research Council Canada,Winnipeg, MB

PROFESSIONAL DEVELOPMENT

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D’Arcy CV,

Lecturer (2001-2003) – NRC/Red River College, MRI/S Technologist ProgramFunctional MRI Research

Laboratory Instructor (1999-2000) - Dalhousie University  Psychology 2000A – Research Methods in Experimental Psychology

Laboratory Instructor (1998-1999) - Dalhousie UniversityNeuroscience 3137A - Research Methods in Cognitive Neuroscience and Advanced Topics in Cognitive Neuroscience

Laboratory Instructor (1997-1998) - Dalhousie UniversityNeuroscience 3137A - Research Methods in Cognitive Neuroscience and Advanced Topics in Cognitive Neuroscience

Teaching Assistant (1996-1997) - Dalhousie UniversityPsychology 3040R - Learning and Motivation

Research Assistant (1995-1996) - University of VictoriaResearch on movement disorders and traumatic brain injurySupervisor: Dr. Catherine A. Mateer

RESEARCH GRANTS

Canadian Foundation for Innovation (CFI)Research Hospital Fund (2004)Cheminformatics and Drug Discovery Laboratory (CDDL)Primary Investigators: Weaver, D. & MacMaster C.Animal MRI Lab Investigators: D’Arcy, R.C.N., Beyea, S.D., Leslie, R., Walter, J. Schmidt, M., and Bolinger, L.Value, $909 126

Canadian Institutes for Health Research (CIHR)Neuroethics New Emerging Teams Grant Program (2004-2009)Primary Investigator: Downie, J.Project 1 - Team Leaders: D’Arcy, R.C.N. & Downie, J.Title: Neuroimaging ethics: From theory to practice.Value $1 500 000 (five years)

Equipment Grant (2002)Investigators: Bolster, B., D’Arcy, R.C.N., McIntyre, M., Clarke, J., & Ryner, L.Title: Equipment for Cognitive Neuroscience and Functional NeuroimagingValue: $6000

Natural Sciences and Engineering Research Council (NSERC) Discovery Grant (2004-2009)Investigator: D’Arcy, R.C.N.

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D’Arcy CV,

Title: Integrating Electrophysiological and Hemodynamic Activation in Human Cognition

Multimodal Imaging in Cognition, value $100 000 (five years)

Nova Scotia Health Research Foundation (NSHRF) Capacity Grant (2004-2005)Investigators: Beyea, S., D’Arcy, R.C.N., Marchand, Y.Title: Understanding Intervention: Building Capacity in Non-invasive Multimodal Neuroimaging, value $10 000

Scottish Rite Charitable Foundation of Canada Physical/Biological Major Research Grant (1999-2001)Primary Investigators: Connolly, J.F. and D’Arcy, R.C.N.Affiliate Investigators: Eskes, G.E., Phillips, S.J., & Harrison, E.R. Title: Biomedical Brain Imaging and Intellectual Disability: Innovative Strategies for

Maximizing Rehabilitative Intervention, value: $105 000 (three years)

Research Grant in Intellectual Disability (1997 - 1998)Primary Investigator: D’Arcy, R.C.N.Title: Neuropsychological assessment of receptive language comprehension with event-related brain potentials , value $7 650

FEE-FOR-SERVICE RESEARCH CONTRACTS

Defense Research and Development Canada (2005)

Cerebral Diagnostics (2003 - 2004)

AWARDS

Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship, (2001), value $70 000; declined

Izaak Walton Killam Memorial Scholarship Dalhousie University (2000-2001)

Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Scholarship B (1999 - 2001), value $38 200

- Top-ranked applicant

Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Scholarship A (1997 - 1999), value $34 600

Dalhousie Graduate Fellowship (DGF)(1996 - 1997), value $14 400

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D’Arcy CV,

Simon Fraser University Graduate Student Fellowship (1996), declined

The President’s ScholarshipUniversity of Victoria (1995 - 1996), value: $750

PEER REVIEWED JOURNAL ARTICLES

D’Arcy, R.C.N., Hamilton, A., Jarmasz, M., Sullivan, S., & Stroink, G. (Submitted). Exploratory data analysis reveals visuo-visual interhemispheric transfer in fMRI.

D’Arcy, R.C.N., Service, E., Connolly, J.F., & Hawco, C.S. (2005). The influences of increased working memory load on semantic neural systems: A high-resolution event-related brain potential study. Brain Research: Cognitive Brain Research, 22 (2), 177-191.

D’Arcy, R.C.N., Ryner, L., Richter, W., Service, E., & Connolly, J.F. (2004). The fan effect in fMRI: Left hemisphere specialization in verbal working memory. NeuroReport, 15 (12) 1851-1855.

D’Arcy, R.C.N., Connolly, J.F., Service, E., Hawco, C.S., & Houlihan, M.E. (2004). Separating phonological and semantic processing in auditory sentence processing: A high-resolution event-related brain potential study. Human Brain Mapping, 22 (1), 40-51.

D’Arcy, R.C.N., Marchand, Y., Eskes, G.A., Harrison, E.R, Major, A., Phillips, S.J., & Connolly, J.F. (2003). Electrophysiological assessment of language function following stroke. Clinical Neurophysiology, 114 (4), 662-672.

Marchand, Y., D’Arcy, R.C.N., & Connolly, J.F. (2002). Linking neurophysiological and neuropsychological measures for aphasia assessment. Clinical Neurophysiology, 113(11), 1715-1722. (Editorial).

Connolly, J.F., Service, E., D’Arcy, R.C.N., Kujala, A., & Alho, A. (2001). Phonological aspects of word recognition as revealed by high-resolution spatio-temporal brain mapping. NeuroReport, 12(2), 237-243.

D’Arcy, R.C.N., Connolly, J.F., & Eskes, G.A. (2000). Evaluation of reading comprehension with neuropsychological and event-related brain potential (ERP) methods. Journal of the International Neuropsychological Society, 6, 552-563.

D’Arcy, R.C.N., Connolly, J.F., & Crocker, S.F. (2000). Latency shifts in the N2b component track phonological deviations in spoken words. Clinical Neurophysiology, 111(1), 40-44.

Connolly, J.F., D’Arcy, R.C.N., Newman R.L. & Kemps, R. (2000). The application of cognitive event-related brain potentials in language-impaired individuals: Review and case studies. Invited review. International Journal of Psychophysiology, 38(1), 55-70.

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D’Arcy CV,

Connolly, J.F., & D’Arcy, R.C.N. (2000). Innovations in neuropsychological assessment using event-related brain potentials. Invited review. International Journal of Psychophysiology, 37(1), 31-47.

D’Arcy, R.C.N., & McGlone, J. (2000). Profound amnesia does not impair performance on the 36-item Digit Memory Test - a test of malingered memory deficits. Brain and Cognition, 54-58.Rotman Research Conference.

D’Arcy, R.C.N., & Connolly, J.F. (1999). An event-related brain potential study of receptive speech comprehension using a modified Token Test. Neuropsychologia, 37(13), 1477-1489.

Connolly, J.F., Major, A.M., Allen, S.L., & D’Arcy, R.C.N. (1999). Performance on WISC-III and WAIS-R NI vocabulary subtests assessed with event-related brain potentials: An innovative method of assessment. Journal of Clinical and Experimental Neuropsychology. 21(4), 444-464.

BOOK CHAPTER

Mateer C.A., & D’Arcy, R.C.N. (2000). Current concepts in assessment and management. S. Raskin & C. Mateer (Eds.). Neuropsychological Management of Mild Traumatic Brain Injury. New York: Oxford University Press.

ARTICLES IN PREPARATION

D’Arcy, R.C.N., Bolster, R.B., Song, X., Runke, D., Ryner, L. (In preparation). Hidden pattern identification in fMRI: What’s in the posterior parietal lobe?

Bolster, R.B., D’Arcy, R.C.N., Ryner, L., Loewen, A., Grant, J., & Clark, J. (In preparation). Temporal lobe involvement in picture-word matching as a function of stimulus category and naming instructions.

Mazerolle, E.L., D’Arcy, R.C.N., & Bolster, R.B. (In preparation). Electrophysiological characterization of temporal lobe activation during visual object recognition.

PUBLISHED ABSTRACTS (AND CONFERENCE PRESENTATIONS)

D’Arcy, R.C.N., Bolster, R.B. Ryner, L., Song, X, & Mazerolle, E. (Accepted). Hidden pattern identification in fMRI: What’s in the posterior parietal lobe? Proceedings of the International Society for Magnetic Resonance in Medicine 13.

Beyea, S.D., D’Arcy, R.C.N., & Marchand, Y.M. (2004). NMR research at the Institute for Biodiagnostics (Atlantic). NMR Spectroscopy. Atlantic Region Magnetic Resonance Centre and the Institute for Research in Materials. (Halifax, poster presentation).

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D’Arcy CV,

Bolster, R.B., D’Arcy, R.C.N., & Ryner, L. (2004). Temporal lobe activation in Picture Naming – Applications to fMRI assessment in epilepsy. Proceedings of the International Society for Magnetic Resonance in Medicine, 12. (Kyoto, poster presentation).

Marchand, Y. Bernier, D. Connolly, J.F., Striemer, C., Rahey, S., & D'Arcy, R.C.N. (2003). How many more "butterflies" are trapped in a passive bodies? Psychophysiology, 40(S1), pp 57. (The 43st annual meeting of the Society for Psychophysiological Research, Chicago, IL, USA).

D’Arcy, R.C.N., Ryner, L., Richter, W., Sullivan, S., Service, E., & Connolly, J.F. (2003). Hemodynamic and electromagnetic correlates of verbal working memory: Integrating functional magnetic resonance imaging and event-related brain potentials. Proceedings of the International Society for Magnetic Resonance in Medicine 11. (Toronto, oral presentation).

Sullivan, S., D’Arcy, R.C.N., Jarmasz, M., MacMaster, F.P., Ryner, L.R., Somorjai, R. (2003). Isolating BOLD correlates of inter- and intra- hemispheric activation during visual processing. Proceedings of the International Society for Magnetic Resonance in Medicine 11. (Toronto, poster presentation).

D’Arcy, R.C.N., Ryner, L., & Richter, W. (2002). Neural interactions between semantic processing and working memory: A functional magnetic resonance imaging study. Society for Neuroscience. (Abstracts). (Orlando, poster presentation).

Connolly, J.F., Marchand, Y. Lefebvre, C., & D’Arcy, R.C.N. (2002). Electrical Neuropsychology – Methods of Linking ERP and Neuropsychological Test Performance. International Journal of Psychophysiology. (Montreal, Connolly).

D’Arcy, R.C.N., Ryner, L., Ryan, B., Mincic, A., Matwiy, B., Matwiy, J., & Porter, M. (2002). Innovative head restraint system minimizes head motion in fMRI. Proceedings of the International Society for Magnetic Resonance in Medicine 10. (Hawaii, USA, Ryner, poster presentation)

Ryan, B., Ryner, L., D’Arcy, R.C.N., Richter, W., Mincic, A., & Porter, M. (2002). Isokinetic dynamometry in the MR environment. Proceedings of the International Society for Magnetic Resonance in Medicine 10. (Hawaii, USA, Ryner, poster presentation)

D'Arcy, R.C.N., Marchand, Y., Connolly, J.F. (2001). ERP assessment of language function following stroke. Psychophysiology (The 41st annual meeting of the Society for Psychophysiological Research, Montreal, Canada, poster presentation).

Connolly, J.F., D’Arcy, R.C.N., & Service, E. (2001). Using the Phonological Mismatch Negativity (PMN) in assembling the electrophysiological architecture of speech processing. Psychophysiology (The 41st annual meeting of the Society for Psychophysiological Research, Montreal, Canada, poster presentation).

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D’Arcy CV,

Marchand, Y. D'Arcy, R.C.N., Connolly, J.F. (2001). Linking neurophysiological and neuropsychological measures. Psychophysiology (The 41st annual meeting of the Society for Psychophysiological Research, Montreal, Canada, poster presentation).

D’Arcy, R.C.N., Connolly, J.F., Service, E., Hawco, C.S., & Houlihan. M.E. (2001). The influences of increased working memory load on semantic neural systems. The 3rd International Conference on Memory (ICOM3 Abstracts), pp. 43. (Valencia, Spain, symposium speaker)

D’Arcy, R.C.N., Eskes, G.A., Harrison, E.R., Marchand, Y., Major, A., Phillips, S.J., & Connolly, J.F. (2001) Neural assessment of receptive language functions in left hemisphere stroke patients. International Journal of Psychophysiology, 41(3), 225 (The 13th International Conference on Event-Related Potential Research, Paris, poster presentation).

- Newcastle Travel Grant for research on Aging, Dalhousie Medical Research Foundation ($1000)

D’Arcy, R.C.N., Connolly, J.F., Gates, L., & Service, E. (1999). An investigation of word and context comprehension using event-related functional magnetic resonance imaging (fMRI). Psychophysiology, 36, s3. (The 39th annual meeting of the Society for Psychophysiological Research, Granada, Spain, symposium speaker)

Newman, R.L., Connolly, J.F., D’Arcy, R.C.N., Cook, D. & Cook, N. (1999). Event Resolution Imaging: Overcoming the limitations of signal averaging in ERP research. Psychophysiology, 36, s85. (The 39th annual meeting of the Society for Psychophysiological Research, Granada, Spain, poster presentation)

D’Arcy, R.C.N., & Connolly, J.F. (1999). Increased processing demands during target error detection on the computerized Token Test. Psychophysiology, 36, s45. (The 39th annual meeting of the Society for Psychophysiological Research, Granada, Spain, poster presentation)

Connolly, J.F., D’Arcy, R.C.N., Major, A.M., Allen, S.L., Eskes, G.A., & Phillips, S.J. (1999). Neuropsychological assessment of receptive vocabulary and comprehension with event-related brain potentials. Psychophysiology, 36, s42. (The 39th annual meeting of the Society for Psychophysiological Research, Granada, Spain, poster presentation)

Gates, L., Connolly, J.F., D’Arcy, R.C.N., & Service, E. (1999). Hemodynamic responses in broca’s area and the visual cortex during sentence reading. Proceedings of the International Society for Magnetic Resonance in Medicine 7, 2, 763. (Philadelphia, USA, Gates, poster presentation)

Connolly, J.F., & D’Arcy, R.C.N. (1999). Assessing cognitive function and consciousness level in non-communicative individuals using event-related potentials. International Journal of Psychophysiology, 30, 84. (The 9th World Congress of the International Organization of Psychophysiology, Taormina, Sicily, Italy, Connolly oral presentation)

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D’Arcy, R.C.N., & Connolly, J.F. (1998). Increased processing demands during target error detection on the computerized Token Test. International Journal of Psychophysiology. (The 12th International Conference on Event-Related Potential Research, Boston, poster presentation)

Connolly, J.F., D’Arcy, R.C.N., Major, A.M., Allen, S.L., Eskes, G.A., & Phillips, S.J. (1998). Neuropsychological assessment of receptive vocabulary and comprehension with event-related brain potentials. International Journal of Psychophysiology. (The 12th International Conference on Event-Related Potential Research, Boston, poster presentation)

Mateer, C.A., & D’Arcy, R.C.N. (1998). The alien hand sign: Insights into the central monitoring of actions and its origins. Canadian Psychology, 39:2a, 128. (Canadian Psychological Association, Edmonton, Mateer oral presentation)

D’Arcy R.C.N., & Connolly, J.F. (1997). An innovative assessment of language comprehension with event-related potentials (ERPs). Psychophysiology, 34, pp. s29. (The 37th Annual Meeting of the Society for Psychophysiological Research, Falmouth, MA, poster presentation)

D’Arcy R.C.N., Connolly, J.F., Byrne, J.M., & Dywan, C.A. (1997). The application of event-related potentials (ERPs) in the assessment of receptive language functions. Psychophysiology, 34, pp. s3. (The 37th Annual Meeting of the Society for Psychophysiological Research, Falmouth, MA, symposium speaker)

PATENT

Ade & Company, USA. October 2002. Connolly, J.F., Marchand, Y., & D’Arcy, R.C.N. Linking neurophysiological and neuropsychological measures for aphasia assessment. #85202-172 ADB

PROFESSIONAL AFFILIATIONS AND ACTIVITIES

Society Membership International Society for Magnetic Resonance in Medicine (ISMRM) Society for Neuroscience (SFN) Society for Psychophysiological Research (SPR) Dalhousie Neuroscience Institute

Committee Membership Brain Repair Commercialization Committee (2004) Premier’s Advisory Council on Innovation, Nova Scotia Economic Development (2004) Neuroimaging Research Laboratory Steering Committee, Chair (2003-present) Brain Repair Centre - Executive Committee (2002-present) Brain Repair Centre – Scientific/Research Committee (2002-present) Graduate Program Committee - Graduate Student Representative (1997 - 1999)

Service to the FieldReviewer

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Brain Research CIHR Biomedical Engineering Clinical Neurophysiology IBD Scientific Review Journal of Clinical and Experimental Neuropsychology

HQP Supervision NRC staff Anderson, N. – Administration (Administrative Assistant, 2002-2003) Bennett, J. – Administration (Administrative Assistant, 2003-present) Beyea, S. – NMR/MRI Physicist (Research Officer, 2003-present) MacMaster, F. – Functional Imaging Specialist (Research Council Officer, 2002-2004) Marchand, Y. – Bioinformatics (Research Officer, 2003-present) Rioux, J. – Biomedical Imaging Research Technician (Technical Officer, 2004-present) Song, X. – Bioinformatics/Neuroscience (Research Council Officer, 2004-present) Sullivan, S. – MRI Technologist (Technical Officer, 2002-2004)

Graduate students Brewer, K. – Graduate student (M.Sc. Thesis committee, 2005) Hamilton, A. – Graduate student (M.Sc. Thesis committee, 2002-2004) Lefebvre, C. – Graduate student (Ph.D. Comprehensive, 2002-2004) Martens, J. – Graduate student (Ph.D. Advisor, 2005) Mazerolle, E. – Graduate student (M.Sc. Advisor, 2005) Whittingstall, K. – Graduate student (Ph.D. Thesis committee, 2003-present)

Undergraduate students Ames, C – Undergraduate student (Women in Engineering and Science, 2003) Crocker, S. – Undergraduate student (Directed studies, 1998-1999) Gibson, E. – Undergraduate student (Honour’s thesis, 2000-2001) Grant, J. – Undergraduate student (Honour’s thesis, 2003-2004) Hawco, C. – Undergraduate student (Directed studies, 2000-2001) Kemps, R. – International student (Directed studies, 1998-1999) Mazerolle, E. – Undergraduate student (WES/Honour’s, 2003-2005)

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Invited lectures (excluding conference lectures listed above) Brain-Machine Interface and Neuroimaging, DRDC Science and Technology

Symposium, Ottawa, Ontario (2005) Clinical Neuroscience Rounds, Dalhousie University, Halifax, NS (2005) Mind in Matter: Behavioural Sciences at NRC, Ottawa, Ontario (2005) Technology Transfer: Applied Science Meets Medicine (keynote), IWK Health Centre,

Halifax, Nova Scotia (2004) Brain/Machine Interface, Department of Defense, Ottawa, Ontario (2004) Halifax Radiologic Society, Halifax, Nova Scotia (2004) NRC’s Institute for Marine Biosciences, Halifax, Nova Scotia (2004) Life Science Development Association, Halifax, Nova Scotia, (2003) Terry Ander’s Memorial Lecture, Neuroscience Institute, Dalhousie University, (2003) Brain Repair Centre Executive Committee, Dalhousie University, (2002) QEII Health Sciences R&D Committee, Halifax, (2002) Institute for Biodiagnostics, Winnipeg, (2001) SUNY at Stony Brook, New York, (2001) Scottish Rite Charitable Foundation of Canada (keynote), (1999) Scottish Rite Charitable Foundation of Canada, (1998)

MEDIA COVERAGE

National and local media coverage on the construction and opening of the Neuroimaging Research Laboratory (2002-2004).

National and local media coverage in the innovative assessment of brain damaged patients (1999-2005).

REFERENCES AND PREVIOUS EXPERIENCE

Available upon request.

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