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8/11/2019 67585737 8 Blood Transfusion
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White bloo d cells
Platelet s
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BLOOD
A mixture of cells
A complex TRANSPORT mechanism Transports hormones
Removes waste products
Regulates body temperature Protects the body
Promotes hemostasis
Supplies oxygen
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BLOOD VOLUME: 8% of total body weight = varies by age & body composition
BloodVolume
Kilograms ofBody Weight
30 kg = 2400mL
80 mL/kgChild
3 kg = 255 270 mL
85 90mL/kg
Neonate
60 kg = 4200mL
70 mL/kgAdultFemale
90 kg = 6300mL
70 mL/kgAdult Male
Blood VolumemL/kgCategory
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COMPOSITION OF BLOOD Temperature 38 C (100.4 F) pH 7.35 - 7.45 Specific Gravity 1.048 1.066 Body weight 7% 5 times the viscosity of water Volume
Male 5 6 Liters Female 4 5 Liters
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Composed of: 55% plasma 45% cellularcomponents
Plasma = fluid portion Coagulation factors Inorganic substances Antibodies
RED BLOOD CELLS
GRANULOCYTES
PLATELETS
PLASMA
Portions of the Blood
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Liquid part of the blood
Consists of serum and fibrinogen
Contains plasma proteins such as:
Albumin = regulates & maintains Serum globulins = for transportation Fibrinogen, prothrombin, plasminogen = to stop the
bleeding
Plasma
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Cellular Components Formed elements of blood
RBC = responsible for oxygen transport
WBC = play a major role in defense againstmicroorganisms
Platelets = function in hemostasis
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Blood: An Emotional Topicthe sweeping story of a
substance that has been feared,revered, mythologized, andused in magic and medicine
from earliest times asubstance that has become thecenter of a huge, secretive, and
often dangerous worldwidecommerce.
From the publishers description of the book
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TRANSFUSION Refers to the administration of any of
several blood products.
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Blood Transfusion may be necessary for anyof the following reasons:
Hemorrhage (blood loss) caused by trauma orhigh blood loss surgery
Red cell destruction
Decreased red cell production
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National Blood Services Act of 994
Also known as the Republic Act 7719 AN ACT PROMOTING VOLUNTARY BLOOD DONATION
PROVIDING FOR AN ADEQUATE SUPPLY OF SAFE BLOOD,REGULATING BLOOD BANKS, AND PROVIDING PENALTIES FORVIOLATION THEREOF.
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Who C N and C NT give Blood
Eligible Donors Must:
Be at least age 18 Weigh at least 110 lb (50 kg) Free from skin disease Not have donated in the past 56 days Have a hemoglobin level of at least 12.5 g/dl
(women) or 13.5 g/dl (men)
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Ineligible Donors include those:
Who have HIV or AIDS Who have taken illegal drugs I.V. Who have had sex with prostitutes in the past
12 months Who have had sex with anyone above
categories Who have had hepatitis With certain types of cancer (other than
minor skin cancer) With hemophilia Who have received clotting factor
concentrations
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Blood Collection Methods 3 Types of Blood Donor Sources for Routine
Blood Collection:
Unrelated Donor (Allogeneic) Directed Donor
Autologous Donor (Self)
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NURSES MUST BE: Knowledgeable about blood products
Safe administration
How to monitor patients before , during andafter therapy
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Assure that informed consent has been obtained before starting a transfusion.
Appropriate information to include in patient educationincludes: Benefits Risks
Alternatives to transfusion
Document all patient education regarding transfusiontherapy , and the responses of patients and familymembers after teaching.
NURSES MUST BE:
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Patient Education Provide patient and family information to blood transfusion
therapy: The need for blood transfusion Advantages of blood transfusion Possible reactions related to the blood transfusion therapy Voluntary blood donation act
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Transfusion Precautions Dont add medications to the blood.
Dont transfuse the blood product if you discover adiscrepancy in the blood number, blood slip type, or
patient identification number. Dont piggyback blood into the port of an existing
infusion set.
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Stop transfusion if your patient shows :
Shows changes in vital signs
Is dyspneic or restless
Develops chills , hematuria , or pain in the
flank, chest or back
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BEFORE TRANSFUSION When assessing your patient before a
transfusion:
Obtain important medical history information Review pertinent laboratory values
Review the doctors order, including any specialprocessing requested
Perform physical assessment
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When you received the delivery from the blood bank,you should receive both the product and thetransfusion record that corresponds to it.
Inspect for the following:
Labels
Integrity of Unit
Appearance
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Perform the verification process to ensure the correct blood is being given to the correct patient .
Two qualified individuals should verify the patient and unitidentification.
Assess the patency of the patients vascular access.
Check and recheck vital signs 15 minutes after starting thetransfusion.
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DURING TRANSFUSION Administer the blood or component at the
recommended rate .
Stay with the patient for the first fewminutes of the transfusion
Review signs and symptoms of what thepatient should report to you.
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Discontinue transfusion immediatelyonce the patient manifest symptoms of
transfusion reaction, assess the patientand notify the doctor.
Finally, document the transfusion in thepatients chart .
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AFTER TRANSFUSION Continue to monitor patient for any signs and
symptoms of reaction for at least one hourafter the transfusion.
Obtain any ordered post-transfusionlaboratory studies.
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BloodProducts
Indications Nursing Considerations
WholeBlood
To restore bloodvolume inhemorrhaging,trauma, or burn
patients
Dont infuse over more than 4hours. Warm blood if giving a largequantity. Avoid giving when the patientcant tolerate the circulatingvolume.
PRBC To restore ormaintain oxygen carrying capacity To correct anemiaand surgical bloodloss
Dont infuse over more than 4hours. RBCs have the same oxygen carrying capacity as whole blood,minimizing the hazard of volumeoverload.
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Platelets To treat
thrombocytopenia To treat acute leukemiaand marrow aplasia
ABO compatibility isnt necessary butis preferable with repeated platelettransfusions; Rh type match is preferred. Infuse 100 ml over 15 minutes. Administer at 150 to 200 ml / hour, oras rapidly as the patient can tolerate; dontexceed 4 hours. Avoid administering platelets when the
patient has a fever.
FFP To expand plasmavolume To treat postsurgicalhemorrhage or shock To correct anundetermined coagulation
factor deficiency
Cross matching: ABO compatibility
isnt necessary but is preferable withrepeated plasma transfusions; Rh typematch is preferred. Large volume transfusions of FFPmay require correction for hypocalcemia.
Citric acid in FFP binds calcium.
BloodProducts
Indications Nursing Considerations
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SAFETY PRECAUTIONS
Make sure that YOU are protected too by:
Wear proper Personal Protective Equipment (PPE) Always perform disinfection technique . If possible, use a needleless system. If using sharps, do not recap the needle . Always observe proper waste disposal according to your
institutions policy. If there are spills, never touch the blood with bare hands . Make sure that blood bag is secured. Always double or triple check. Always perform HAND HYGIENE
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Acute Transfusion Reactions usually appearwithin the first 5-15 minutes after thetransfusion is started.
Types of Acute Transfusion Reactions: Acute hemolytic Transfusion Reaction Febrile nonhemolytic Transfusion Reaction Mild allergic (Urticarial) Anapylactic
Transfusion Associated Circulatory Overload Transfusion Related Acute Lung Injury Septic Transfusion Reaction
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Symptoms you might see during an acute transfusionreaction include:
Temperature increase of more than 1 C or 2 F Bloody urine Chills Hypotension Severe low back, flank, or chest pain Low or absent urine output Nausea and vomiting Dyspnea, wheezing Anxiety, "sense of impending doom" Diaphoresis Generalized bleeding, especially from punctures and surgical
wounds.
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WHAT TO DO IF TRANSFUSION REACTIOCCURS
When they do occur, it is usually becauseof ABO incompatibility between patient
and donor during transfusion of red cells.
Ensure that the intended recipient is
getting the intended unit at the time oftransfusion.
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Should any of these symptoms occur, discontinue the unit immediately,hang normal saline (on a new tubing) to maintain vascular access, and callfor assistance.
Closely monitor the patients vital signs and symptoms.
Notify the physician and obtain further orders to address the patientssymptoms.
Recheck the patients identifying information against the transfusion
record and blood bag.
All bags, tubings, filters, and paperwork should be retained and forwardedper hospital policy.
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Infusion device used Flow rate and if blood warming was used Vital signs obtain prior to, during, and after the
transfusion Name of the component, unit number Evidence of possible transfusion reaction.
Document interventions done and to whom you notified. Patients outcome.