53rd Annual Meeting

January 17-19, 2020 Vinoy Renaissance® St .Petersburg Resort & Golf Club

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PROGRAM COMMITTEE

Chair: David Roth, M.D.

University of Miami Miller School of Medicine

Miami, FL

Nabeel Aslam, M.D. Mayo Clinic

Jacksonville, FL

William Haley, M.D. Mayo Clinic

Jacksonville, FL

Richard Handler, M.D. Vero Renal Associates

Vero Beach, FL

Rute Paixao, M.D. Cleveland Clinic Florida

Weston, FL

Reinaldo Rosario, M.D. Renal Electrolyte &

Hypertension Consultants Fort Lauderdale, FL

Vinayak Purandare, M.D. Vinayak V. Purandare, M.D., P.L.

Daytona Beach, FL

President Reinaldo Rosario, M.D.

Florida Kidney Physicians Fort Lauderdale, FL

53rd Annual MeetingVinoy Renaissance® St .Petersburg Resort & Golf Club

53rd Annual Meeting

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02017-2019 OFFICERS DIRECTORY

FSN STRATEGIC PLAN

ACCREDITATION STATEMENT

President: Reinaldo Rosario, M.D.

Florida Kidney Physicians Fort Lauderdale, FL

Immediate Past-President: David Roth, M.D.

University of Miami Miami, FL

Vice-President: Avon Doll Jr., M.D.

North Florida Nephrology Associates

Tallahassee, FL Treasurer:

Ashok Sastry, M.D. Nephrology Associates Sarasota

Sarasota, FL

MISSION:

FSN represents and serves the interests of Florida nephrologists in their pursuit and delivery of quality care for patients with kidney disease.VISION:

FSN is the recognized advocate for nephrologists in Florida.Strategic Priorities – Statement of Relevancy

Education FSN will deliver quality educational opportunities to promote advanced care for the treatment of patients with kidney disease.Regulatory & Legislative Advocacy

FSN will be the definitive advocate for nephrologists influencing economic and public policy, representing the collective voice of nephrologists.

Practice Management Success FSN will provide nephrologists tools and knowledge to achieve practice success.Patient Care

FSN will provide nephrologists resources to deliver high quality, safe patient care in an economically feasible manner.Grassroots Communication

FSN will facilitate collaboration between nephrologists practicing throughout Florida.Collaboration – Partnerships

FSN will work with organizations that strive to enhance nephrology and quality care for patients with kidney disease.

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Florida Medical Association and the Florida So-ciety of Nephrology. The Florida Medical Association is accredited by the ACCME to provide continuing medical education for physicians. The Florida Medical Association designates this live activity for a maximum of 8.0 AMA PRA Category 1 Credits™. Physicians

should claim only the credit commensurate with the extent of their participation in the activity.Successful completion of this CME activity, which includes participation in the evaluation component enables the participant to earn up to 4.5 MOC points in the American Board of internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit par-ticipant completion information to the ACCME for the purpose of granting ABIM MOC credit.

Secretary: Arvind Madan, M.D.

Nephrology Associates of Central Florida

Orlando, FL Directors At Large:Jose Arrascue, M.D.

South Palm Beach Nephrology Atlantis, FL

Nabeel Aslam, M.D. Mayo Clinic

Jacksonville, FLMauro Braun, M.D.

Cleveland Clinic Florida Weston, FL

Richard Handler, M.D. Vero Renal Associates

Vero Beach, FL

Marco A. Ladino-Avellaneda, M.D. University of Miami

Miami, FL Rute Paixao, M.D.

Cleveland Clinic Florida Weston, FL

Vinayak Purandare, M.D. Vinayak V. Purandare, M.D., P.L.

Daytona Beach, FL Alternative CAC Representative

Arvind Madan, M.D. Nephrology Associates of Central

Florida Orlando, FL

Past Presidents Council Rep William Haley, M.D.

Mayo Clinic Jacksonville, FL

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ABOUT OUR DESTINATION

The Vinoy® Renaissance St. Petersburg Resort & Golf Club welcomes you to Florida with a seamless combination of historic charm and modern convenience. Our award-winning hotel is situated in the city’s vibrant downtown district, just a short distance from attractions including Tropicana Field and the Dali Museum, as well as the Florida Aquarium and miles of pristine beaches. Gracefully designed rooms and suites feature home-like comforts; some also offer balconies with views of the water. Our hotel is a destination unto itself, with a championship golf course, a serene on-site spa and a private marina. Play a game of tennis, embark on a boat ride, dine at one of our excellent restaurants or simply laze by one of the pools and enjoy the warm St. Pete weather. If you’re planning an event in the area, you’ll be delighted with our expansive venues, which are tailor-made for weddings, meetings and everything in between. We eagerly await your arrival at The Vinoy® Renaissance St. Petersburg Resort & Golf Club.

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02020 FSN ANNUAL MEETING FACULTY

Dr. Gerald B. Appel is Director of Clinical Nephrology at Columbia University Medical Center at The New York-Presbyterian Hospital, New York, New York, and is a tenured Professor of Clinical Medicine at Columbia University College of Physicians

and Surgeons. He is Chief of the Glomerular Kidney Disease Center at Columbia U. He received his undergraduate BA from Cornell University graduating in three years with distinction in all subjects and as a member of phi beta kappa. He received his medical degree from Albert Einstein College of Medicine, Bronx, New York, in 1972., where he was elected to the medical honor society Alpha Omega Alpha. He completed his internship and residency in Internal Medicine at Columbia Presbyterian Medical Center. He then completed fellowships in Nephrology at both Columbia-Presbyterian (1975-1976) and at Yale-New Haven Medical Center, New Haven, Connecticut (1976-1978).

Dr Appel has been listed in New York Magazine as one of the “Best Doctors in New York” annually between 1992 and 2010, and is listed in “Best Doctors in America,” and also in “How to Find the Best Doctors in N.Y. Metro Area.” He is an associate editor of Clinical JASN and of Up-To-Date. Dr. Appel is a member of numerous societies and has served on the Medical Advisory Board and as the Chairman of the Research Committee of the National Kidney Foundation of New York and New Jersey and The Kidney and Urology Foundation of America, as a past president of the New York Society of Nephrology, and as Chair of the Council of Glomerulonephritis of the National Kidney Foundation of the US. He is the director of many courses including The Columbia U Internal Medicine Course in NYC , Renal Biopsy in Medical Diseases of the Kidney in NYC, and The Treatment of Glomerular Diseases at the annual American Society of Nephrology meetings. Dr Appel has authored and co-authored almost 300 peer-reviewed articles and book chapters.

Dr. Gerald B. Appel

Robert Blaser has served as RPA’s Director of Public Policy since October 2003, and previously as RPA’s Director of Federal Affairs since September 1997. From June 1995 to September 1997, Rob served as RPA’s Regulatory Analyst. Among Rob’s primary areas of

responsibility since joining RPA are management of RPA’s legislative and regulatory portfolios, and policy development for the organization. In this latter role Rob has taken the lead in drafting over 30 position papers for RPA. Rob has also developed expertise

in such diverse areas as legislative developments affecting renal care, physician reimbursement in the Medicare Fee Schedule (MFS), and other issues pertaining to CKD-specific coverage and reimbursement issues. Prior to joining RPA, Rob served as Director of Subspecialty Representation for the American College of Physicians (ACP), providing government affairs services for organizations representing rheumatologists, clinical endocrinologists, and general internists, among other specialties. He also previously had a decade of experience in the private insurance industry.

Robert Blaser

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2020 FSN ANNUAL MEETING FACULTY

Dr. Asher Chanan-Khan is dedicated to advancing and discovering treatments for patients with chronic lymphocytic leukemia (CLL), Waldenstrom macroglobulinemia, and multiple myeloma. He works very closely with both his clinical and research staff to support and improve the quality of life of these patients.

For over a decade, Doctor Chanan-Khan has been engaged both in the development of novel therapeutics (the branch of medicine that deals with the treatment and cure of diseases) and extensive laboratory research. His expertise is in preclinical target validation and drug evaluation directed towards early phase clinical trials.Doctor Chanan-Khan has actively contributed to the development of immunomodulating drugs (thalidomide

and its analogs) in both CLL and multiple myeloma. In CLL, he is credited for introducing lenalidomide and defining its potential as a new therapeutic. In addition, he has been actively involved in the evaluation of other promising agents through phase I and II trials. In multiple myeloma, he has been involved in the development of various therapeutics (alone and in combinations) including proteasome inhibitors (bortezomib, carfilzomib) along with novel monoclonal antibodies. These efforts remain the focus of his continued research.Doctor Chanan-Khan has been principal investigator or co-principal investigator on numerous clinical trials for patients with these disorders and has authored more than 200 publications related to CLL and multiple myeloma.He serves in leadership roles on several Mayo Clinic, national and international committees relating to these diseases.

Dr. Asher Chanan-Khan

Dr. Gabriel Danovitch received his medical degree from St Bartholomew’s Hospital of the University of London. He completed his residency training in London and in Bersheeba, Israel and his nephrology fellowship training at Albert Einstein College of

Medicine in New York City. He served on the faculty at Albert Einstein and then directed the nephrology unit at Soroka Hospital in Israel. He currently holds the John J. Kuiper Chair in Nephrology and Renal Transplantation at the David Geffen School of Medicine at UCLA with the academic rank of Distinguished Professor of Medicine. He is the longtime Medical Director of its renowned Kidney and Pancreas Transplant Program: one of the largest and most successful in the US. Dr. Danovitch has devoted his recent career to various aspects of clinical kidney transplantation. He

has published over 180 original articles and 50 book chapters. He has mentored a generation of transplant physicians and leads the UCLA AST/ASN kidney transplant medicine fellowships since its inception. Dr. Danovitch is an internationally recognized authority on transplant immunosuppression, clinical transplant care, transplant ethics and public policy. He has served on the board of the American Society of Transplantation (AST) and the United Network for Organ Donation (UNOS) and is the past Chair of its International Relations committee. He is a founder member of the Custodian Group of the Declaration of Istanbul on Organ Trafficking and Transplant Tourism (DICG) and now serves as its Co-Chair. He is Medical Director of OneLegacy, the organ procurement agency of Southern California. His classic textbook, the Handbook of Kidney Transplantation, now in its fifth edition and translated into five languages, has become required reading for those entering the field.

Dr. Gabriel Danovitch

2020 FSN ANNUAL MEETING FACULTY

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Dr. Richard Glassock is an internationally recognized expert in the field of Glomerular Diseases and Clinical Nephrology (Kidney Disease). He has published over 600 original papers, books, book chapters and reviews. He is the past-president of the American

Society of Nephrology, the National Kidney Foundation (USA) and past-Chairman of the American Board of Internal Medicine. He is a member of the American Association of Physicians, the American Clinical and Climatological Association and in 1999 was elected to Mastership in the American College of Physicians. He is the former Chair of the Departments of Medicine at the University of Kentucky (1992-1999) and Harbor-UCLA Medical Center (1980-1992). From 1967 to 1980 he was also the Chief of the Division of Nephrology and Hypertension at Harbor-UCLA Medical Center. He was continuously funded for his Research by the National Institutes of Health from 1967 to 1992. He has lectured in over 95 countries throughout the world, been a visiting professor at over 100 academic institutions and trained over 50 nephrologists, many of whom have gone on to distinguished academic posts throughout the world. He is an honorary member

of many International Nephrology Societies. He is a long-standing member of the Editorial Board of the Journal of the American Society of Nephrology, Kidney International and the American Journal of Nephrology. He was the founding Editor-in=Chief of the NephSAP Journal of the American Society of Nephrology (2002), and continues as an Associate Editor of this Journal. He is a member of the Board of Directors of the Los Angeles Biomedical Research Institute and the University Kidney Research Organization. He is Vice-President of the Laguna Niguel Rotary Club, where he has been member since 2000, and he is a Paul Harris Fellow of Rotary International.Doctor Glassock has received numerous awards and distinguished lectureships including the David Hume Memorial Award of the National Kidney Foundation, The Robert Narins Award of the American Society of Nephrology, and Distinguished Achievement Awards from both the UCLA School of Medicine and the Association of Professors of Medicine. He has received the Torchbearer Award of the American Kidney Fund and the Medal of Excellence of the American Association of Kidney Patients. In 1999 he retired from Academic administration and is currently Professor Emeritus at the David Geffen School of Medicine at UCLA and an independent medical consultant.

Dr. Richard Glassock

Dr. Jamie P. Dwyer’s clinical expertise centers around kidney disease (in general) but specifically diabetic kidney disease and other glomerular lesions, including glomerulonephritis. He has developed expertise in the evaluation, management, and

prevention of kidney stones (nephrolithiasis). His clinical research has focused on these areas as well, particularly on the design, conduct, and analysis of large-scale randomized clinical trials (RCT) in nephrology and hypertension, particularly in delaying the progression of chronic kidney disease (CKD). He is the Co-Director of the Vanderbilt Nephrology Clinical Trials Center, a founding part of the Vanderbilt Center for the Study of Kidney Disease. Additionally, he is an Officer of the Collaborative Study Group (CSG), a international, non-profit organization dedicated to the exceptionally rigorous design and analysis and safe conduct of pilot and multinational, large-scale,

pivotal RCTs in relevant therapeutic areas, including CKD, diabetic nephropathy, lupus, lupus nephritis, and end-stage renal disease. His expertise centers around protocol design, medical monitoring, trial conduct, and safety.He has participated on numerous Protocol Design, M&M, and DSMB committees. He has served as the Medical Monitor for multiple compounds and trials. To support his expertise in safe conduct of trials, he currently serves as the Vice-Chair of my University’s Health Science’s Institutional Review Board. He has analyzed renal safety signals in non-renal clinical trials presented to the FDA. Additionally, he is interested in investigating alternative, proximal outcomes in large RCTs in nephrology which will increase event rates, reduce follow-up time, and reduce sample sizes, in order to speed intervention development to delay the progression of CKD. Finally, as part of this interest in endpoint analysis, he is interested in the measurement of renal function and its implications for the design and choice of endpoints in large RCTs.

Dr. Jamie P. Dwyer

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2020 FSN ANNUAL MEETING FACULTY

Dr. Glen Markowitz eceived his undergraduate degree from Brandeis University in 1990 and his MD from Albert Einstein College of Medicine in 1994. After three years of residency in anatomic pathology at Albert Einstein College of Medicine, he spent a year as the Renal Pathology Fellow at Columbia University in 1997-8,

training under Dr. Vivette D’Agati. He subsequently joined the faculty at Columbia University, College of Physicians & Surgeons in 1998 and has remained

on the faculty since that time, achieving the rank of Professor of Pathology & Clinical Pathology in 2008 and assuming the role of Vice Chairman for Operations in 2011. During 2015, he is serving a 1-year term as the President of the Renal Pathology Society, the largest organized body of renal pathologists in the world, with a current membership that exceeds 550. Dr. Markowitz’s areas of academic interest include toxic forms of renal injury, dysproteinemic renal disease, and membranous glomerulopathy. He has published more than 160 articles and many additional chapters.

Dr. Glen Markowitz

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FRIDAY, JANUARY 17, 2020

SATURDAY, JANUARY 18, 2020

53RD ANNUAL MEETING PROGRAMJanuary 17-19, 2020

Vinoy Renaissance ResortSt Petersburg, FL

2:00-4:30 PM Avery/Chancellor Room FSN Executive Committee Meeting

4:30-5:00 PM Fred’s Corporate Member Appreciation Reception (Invitation Only)5:30-6:30 PM Mezzanine South/ Terrace Medical Student and Mentor Reception (Invitation Only)6:30-8:00 PM Esplanade Presidential Welcome Reception

8:00 PM Location-Invitation Only Executive Committee & Faculty Dinner Canopy-The Birchwood Hotel Medical Student & Mentor Dinner

7:30-9:00 AM Exhibit Hall – Royal Ballroom Registration and Breakfast

8:00–10:00 AM Plaza AB ANNA State Chapter Programming

Majestic Ballroom GENERAL SESSION 1

9:00-9:05 AM Welcome President, Reinaldo Rosario, M.D. Renal Electrolyte & Hypertension Consultants Fort Lauderdale, FL

Moderator: Nabeel Aslam, M.D. Mayo Clinic, Jacksonville, FL

9:05-9:50 AM Role of SGLT-2 Inhibitors in Diabetic and Non-Diabetic Kidney Disease (MOC Eligible) Jaime P. Dwyer, M.D., Vanderbilt University Medical Center

9:50-10:00 AM Discussion

10:00-10:10 AM MOC Questions

10:10-10:45 AM Exhibit Hall – Royal Ballroom Break with Exhibitors

Majestic Ballroom GENERAL SESSION II Moderator: Reinaldo Rosario, M.D. Renal Electrolyte & Hypertension Consultants Fort Lauderdale, FL

10:45-11:30 AM Focal and Segmental Glomerulosclerosis: Not a Disease but a Lesion of Many Causes (MOC Eligible) Richard J. Glassock, M.D., Laguna Niguel, CA

11:30-11:45 AM Discussion

11:45-11:50 AM MOC Questions

12:00-1:00 PM Renal Physicians Association Lunch Program: Hot Topics in Nephrology Reimbursement & Practice Management Robert Blaser, Director of Public Policy Renal Physicians Association

12:00-1:00PM General Attendees – Lunch on Own

12:00-1:00 PM Plaza CD Mentor & Student Lunch (Invitation Only)1:15-3:15 PM Plaza AB ANNA State Chapter Programming

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SATURDAY, JANUARY 18, 2020

SUNDAY, JANUARY 19, 20207:30-8:30 AM Exhibit Hal-Royal Ballroom Registration and Breakfast

8:30AM-12:00PM Majestic Ballroom GENERAL SESSION III Session Moderator: Avon Doll, M.D. North Florida Nephrology Associates, Tallahassee, FL

8:30–9:00 AM Current Understanding of Plasma Cell Disorders (MOC Eligible) Asher Chanan-Khan, M.D., Mayo Clinic, Jacksonville, FL

9:00–9:10 AM Question and Answer Session

9:10-9:15 AM MOC Questions

9:15-9:30 AM FSN Business Meeting

9:30-10:00 AM Exhibit Hall-Royal Ballroom Break with Exhibitors

Majestic Ballroom GENERAL SESSION IV

Session Moderator: Rute Paixao, M.D. Cleveland Clinic, Weston, FL

10:00-10:40 AM Can YOU be a Kidney Transplant Donor? (MOC Eligible) Gabriel M. Danovitch, M.D. Connie Frank Kidney Transplant Center, UCLA, Los Angeles, CA

10:40-10:50 AM Discussion

10:50-10:55 AM MOC Questions

10:55-11:40 AM New Data on RPGN- ANCA Vasculitis and Anti-GBM Disease (MOC Eligible) Gerald Appel, M.D. Columbia University Medical Center, New York, NY

11:40-11:50 AM Discussion 11:50-12:00 PM MOC Questions 12:00 PM Closing Remarks

David Roth, M.D., Program Chairman Adjournment – 53rd Annual Meeting

1:15 PM Majestic Ballroom GENERAL SESSION Moderator: David Roth, M.D. University of Miami/Miller School of Medicine, Miami, FL

1:15-1:45 PM 12th Annual Robert Geronemus Memorial Renal Fellows Research Competition

1:45-4:00 PM Clinicopathological Enigmas: Challenging Cases in the Diagnosis and Management of Glomerulonephritis Glen Markowitz, M.D. Columbia University Medical Center, New York, NY

Gerald Appel, M.D. Columbia University Medical Center, New York, NY

Richard J. Glassock, M.D., Laguna Niguel, CA4:00-4:30pm Lassing/Miller Debrief with Medical Students

4:00-6:00pm Majestic Ballroom PRE-RECEPTION SYMPOSIUM - Sponsored by AMGEN (Non CME) A Treatment Option for Secondary Hyperparathyroidism (HPT) in Adult Patients on Hemodialysis Stuart Sprague, D.O. University of Chicago Pritzker School of Medicine, IL

6:00-7:30 PM Exhibit Hall-Royal Ballroom Reception

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The Florida Society of Nephrology would like to recognize & thank the following partners who have registered to participate in the 2020 Annual Meeting.

PRELIMINARY EXHIBIT SHOW

HOURS

Thank you….

PLATINUM

Amgen, Inc

GOLD

CareDx Horizon Therapeutics

BRONZEAlexion, CM GroupAstraZenecaDavita, IncFresenius Kidney Care North/South Florida RegionMallinckrodt PharmaceuticalsOPKO Health Renal DivisionRetrophin

SILVERMedPro Group & Danna-Gracey

CLASS 1 EXHIBITORS

CLASS 2 EXHIBITORS

Amicus TherapeuticsB. Braun Medical IncClevelnd Clinic FloridaGenentech - A member of the Roche GroupMedCompNational Kidney Foundation of Florida

NephroChoiceNxStage MedicalOtsuka Pharmaceutical Development & CommercializationPentec HealthU.S. Renal CareVeloxis Pharmaceuticals Inc

Akebia Therapeutics, IncAlnylam PharmaceuticalsArkana LaboratoriesAzura Vascular CareBaxterFresenius - Renal PharmaceuticalsJackson Health SystemNEPHRO-TECH, Inc

N’Sync ConsultingProAssuranceRelypsaRetrophinRockwell MedicalShire / TakedaTakeda PharmaceuticalsUF Health Pathology LaboratoriesUF Health Transplant

SET-UP: Friday, January 17

2:00 - 5:00 PM6.00 - PM

(Welcome Reception)

SHOW HOURS: Saturday, January 18

7:30 - 9:00 AM (Breakfast)10:10 - 10:45 AM (Break)

6:00 - 7:30 PM (Reception)Sunday, January 19

7:30 - 8:30 AM (Breakfast)9:30 - 10:00 AM (Break)

BREAK DOWN: Sunday, January 19 10:05 AM - 1:00 PM

SOCIAL EVENT

• • There is no dinner events on Friday or Saturday after the reception. Please feel free to make individual plans to have dinner with attendees.

• The Welcome Reception on Friday is a great social event. This event is not held in the exhibit hall.

• Our main event the Saturday Reception is in the Exhibit Hall.

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FSN WOULD LIKE TO RECOGNIZE OUR CORPORATE SPONSORS

FLORIDA SOCIETY OF NEPHROLOGY1215 E ROBINSON STREET, ORLANDO FL 32801

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