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A Decrease protein and albuminin the body

Synthesis of lipoprotein

hyperlipidemia

Decrease oncotic pressure

Fluid shifting

Decrease fluid in the

circulation

RAAS activation

C

C

Muscle weakness, fatigue and

poor appetite

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B

Decrease concentration of

urine

Decrease specific gravity and

pH

Acidosis

Hyperventilate

Decrease erythropoiesis

Diminished blood flow

Decrease GFR

RAAS activation

Hypoxemia to different tissue

stomach

constipation

Impedes function of kidney

kidney

Anaerobic metabolism

Increase amount of acidOliguria and increase waste

product in the blood

Unable to excrete wastesIncrease creatinine and

potassium

Accumulates in the b

seizure

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C RAAS activation

Sodium and Water Retention

Compression of diaphragm

ascites accumulation of fluid in the

lung capillaries

Fluid shifting

Difficulty of breathing

Pulmonary hypertension

Increase pulmonary arterial

pressure

Rupture of microvascular

aneurysm

Hemoptysis

Increase blood volume

Generalized edema(ANASARCA)

Periorbital edema

Facial edema

Ascites

Edema on both upper and

lower extremities

Hypertension