4th year syllabus.pdf - BIO-CHEMICAL ENGINEERINGcbit.ac.in/files/4th year syllabus.pdf · Sessions :30 Duration of Exam. : 3 Hrs. ... Biochemical Engineering Principles, ... 4th year

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  • BIO-CHEMICAL ENGINEERING

    C.E.T. :4.201 Periods per week : 4

    Sessions :30 Duration of Exam. : 3 Hrs. Examination :70 Nature of Exam. : Theory.

    UNIT - I: Introduction to Biochemical Engineering & Molecular Biology Biochemical Engineering Principles, Biophysics and cell doctrine: Atomic Theory and Cell Theory, Important cell types, structure and functions of a typical cell and their components, Transport across cell membranes: Passive and facilitated diffusion, Active transport Structure and functions of Bio Molecules: Carbohydrates, lipids, Nucleotides to Nucleic Acids - R N A and DNA, Amino acids to Proteins - the building blocks of biochemical life. Biosynthesis and Metabolic Pathways: Biosynthesis of Small and Macro Molecules Introduction of metabolic pathways and end products of glucose metabolism. UNIT - II: Introductory Microbiology Introduction to Microbiology: Classification and Industrial uses of Microorganisms Growth and Reproduction of Microbes: Growth cycle phases for batch cultivation. Monods growth kinetics Growth Rate dependant classification of Microorganisms Microbial Genetics: Recombinant DNA technology and mutant populations Multiple Interacting Microbial populations: Neutralism, Mutualism, Commensalism, Amenalism, Predatism and Parasitism UNIT - III: Enzyme Technology Enzymology: Enzymes as Biocatalysts - The enzyme substrate complex and enzyme action and Classification of Enzymes based on Functions Kinetics of Enzyme Catalyzed Reactions: Simple enzyme kinetics with one and two substrates. Determination of rate constants, substrate activation and inhibition, modulation and regulation of enzyme activity / effect of PH and temp on enzyme activity. Immobilized Enzyme Technology: Types of Enzyme immobilization, Immobilized enzymes in industrial processes, Cofactors, Apo-enzymes and Coenzymes utilization and regeneration UNIT - IV: Bioreactors and Down Stream Techniques - Introduction Design and Analysis of Biological Reactors: Batch and CSTR reactors, Enzyme reactors Ideal Reactors for kinetic measurements: The ideal batch reactor / The ideal continuous flow stirred thank reactor - Alternate bio-reactor configurations Separation Processes: Filtration, Centrifugation, Adsorption, Reverse osmosis, Dialysis, Electrophoresis, Sedimentation and Extraction Purification Processes: Precipitation, Crystallization, and Chromatography UNIT - V: Bioprocess Technology Fermentation Technology: Types of Fermentation - Anaerobic and Aerobic Fermentation process. Surface and Submerged Fermentation process Medium formulation and Culture Propagation: Media composition and Sterilization, Inoculums culture development under aseptic conditions of transfer. Environmental biotechnology: Effluent treatment. Industrial Biotechnology: Commercial enzymes, Antibiotics and single cell protein

    EXAMINATION: One question from each unit with internal choice. TEXT BOOK : Biochemical Engineering fundamentals, by James, E.Bailey and David F Ollis, II Edition, 1986. McGraw-Hill Internal Edition.

  • PLANT DESIGN & ECONOMICS

    C.E.T. : 4.202 Periods per week : 4 Sessionals : 30 Duration of Exam. : 3 Hrs.

    Examination : 70 Nature of Exam. : Theory.

    UNIT I

    Evolution of process, process design including material and energy balance flow sheets and engineering flow diagrams selection procedure for process equipment such as selection of size reduction equipment, material handling equipment, size separation equipment, evaporators, heat exchanger, filtration units and dryers, Material of construction for equipment, Safety Considerations. UNIT II Principles of plant layout, plot plans, piping engineering, sizing, selection, materials for piping (ferrous and non-ferrous and plastics); layout, stress design and installation (excluding drainage/under ground piping). UNIT III Process industries Capital and interests, economics and process engineering, value of money, equations for economic studies, equivalence. The bond, capital recovery, depreciation, interest in depreciation capital. UNIT - IV Cost indices, equipment cost, the Williams six-tenths factor, service facilities, capital requirements for complete plants, total and process investment, the balance sheet, sources of capital, Variable cost, fixed cost, use of cost data, profits and earnings economic production charts. UNIT - V Annual cost method, present worth method, equivalent alternatives, rate of return method, pay out lime method, effect of source of capital, replacement of existing facilities.

    Examination : One question from each unit with internal choice.

    TEXT BOOKS : 1.Chemical Engineering plant Design by C.Vilbrandt and Dryden C.E. 4th Edition, Mc Graw Hill Book Co., 1959. 2.Process Engineering Economics by H.E. Schweyer, Mc Graw Hill Co., New York,Kogakusha Co., Ltd., Tokyo. 1955.

  • PRINCIPLES AND PRACTICE OF MANAGEMENT

    C.E.T. : 4.203 Periods per week : 4

    Sessionals : 30 Duration of Exam. : 3 Hrs. Examination : 70 Nature of Exam. : Theory.

    Objectives: To give the basic concepts of management ( A brief study of some the topics) and application in areas like purchase, Finance, HRD, Production, and Marketing with reference to Chemical and Food Industries. UNIT - I Management definition, Administration Vs Management Principles and Functions of Management, levels of management - System and Contingency approach to management - steps in Planning - Forecasting methods - Decision making process - organization : Definition , Line, staff, functional and matrix type organization, span of control (Graicuna`s Formulae), Centralization Vs Decentralization. UNIT - II Coordination Vs Cooperation - Direction Vs Supervision - Communication : process, grapevine, networks and barriers of communication - Managerial grid, Theory of X, Y and Z; Job Enrichment Vs Job enlargement - Control process - Introduction to Personnel Management: Functions, staffing process, need fro HRD, Training & Development (TWI Programme) UNIT - III Measurement of Morale - Job Design -Industrial Relations: Human relation Vs Industrial relations, Trade Unionism, Industrial Unrest, Wage and Incentive concepts - Role of ILO - MIS in industry - Management of public enterprises. UNIT - IV Introduction to Financial Management : Sources of Finance, capital & its structure (CFS & FFS) Financial statements, cost sheet - Introduction to Purchase & Material management Purchasing objects and principles, types of purchasing, Vendor selection, rating, evaluation & Development - Inventory control, ABC analysis, stores organization and pricing of issues - concept of Warehousing. UNIT - V Production & Marketing Management : Types of Production, Quality control (Tools used), PPC, Maintenance management - Marketing management ; Definition and concept of marketing, functions of marketing, market research, Types of markets, Sales Forecasting and promotion - Pricing - Advertising Strategy - Product Identification - A brief note on International Marketing. Examination : One Question from each unit with internal choice. Reference Books: Principles and Practice of Management - T.N.Chhabra, Dhanpat Rai & Sons, New Delhi (6th edition, 2000) Principles and Practice Management - L.M.Prasad, Sultan chand Publications, New Delhi (6th edition, 2001)

  • PROCESS EQUIPMENT DESIGN

    C.E.T. : 4.204 Periods per week : 4 Sessionals : 30 Duration of Exam. : 3 Hrs.

    Examination : 70 Nature of Exam. : Theory.

    UNIT - I Design of Pressure Vessels : General design considerations of pressure vessels, design of thin-walled vessels for internal pressure and external pressure, design principles of tall columns. UNIT II Design of vessel components.:Types of flanges, design of loose type non-standard flanges, compensation requirements for openings and branches. Impellers stuffing box and design of shaft. Types and selection of equipment supports. UNIT III Design of heat transfer equipment:Shell and tube exchangers construction details TEMA standards and general design considerations. Kern`s methods of Process design of exchangers for sensible heat transfer. Design of shell & tube condensers (excluding multi component condensers). & Design of 1-2 shell and Tube Exchangers in series. UNIT IV Continuous stage wise distillation column (Binary systems), design variables Mc Cab hile Method Low product concentration smoker equations prediction of plate efficiency - column sizing. Distillation with side streams and multiple feeds. Choice of plate verses packed columns. Selection of column pressure. UNIT V Plate contactors selection of plate type plate constructions - sieve plate hydraulics design. Design of sieve plates - Down Comer design. Examination : One question from each unit with internal choice BOOKS RECOMMENDED : 1.Chemical Engineering, Vo1. 6 3/e Chem Engg.; Design by J.M.Coulson, J.F.Richardson and R.K. Simmott Butter worth - Heinemann 1999. 2.Process Heat transfer, by D.Q. Kern, McGraw Hill Book. Co., 1997 3.Code for unfired pressure vessels Is 2825. 4.Process Equipment Design by M.V.Joshi Macmillan India Ltd, 1981.

  • EQUIPMENT DESIGN AND DRAWING LAB

    C.E.P. : 4.205 Periods per week : 4 Sessionals : 25 Duration of Exam. : 6 Hrs.

    Examination : 50 Nature of Exam. : Practical.

    Drawings of symbols in flow sheets, piping, instrumentation on and other flow sheets. Flow sheet development work and drawings of few flow sheets. Mechanical designs and drawings of vessels under external and internal pressures, reactor kettles, heat exchangers, evaporators, plate and packed column. Typical layout and elevation drawing, simple piping pipe work design and drawings.

    BOOKS RECOMMENDED : 1.Vilbrandt, C.T. and Dryden, C.E., Chemical Engineering plant design, International Student Edition, Fourth Edition, Kogakusha. 2.Joshi, M.V. Process Equipment Design, 2nd Edition, McMillan Co. of India Limited, Madras, 1932. 3.Bachurst, J.R. and Harker, J.A. Process Plant Design, Heiman Education Books, London, 1973. 4.Evans, F.L., Equipment Design Hand Book for refineries and Chemical Plants, Vol .I, 1979, Vol. II, 1980, Gulf Publishing Co., Houston, Texas.

  • PROJECT REPORT

    C.E.P : 4.206 Periods per week : 8 Examination : GRADES Nature of Exam : Report

    Evaluation & its defence.

    Each student is required to work on a comprehensive project on a topic given by the Department and submit a report.

    A. - Grade : Very Good

    B - Grade : Good

    C - Grade : Satisfactory

    F - Grade : Not Satisfactory ( Fail)

    If any candidate is awarded F-Grade , he/she has to submit the revised Project report for evaluation & defence once again.

  • SEMINAR

    C.E.P : 4.207 Periods per week : 1 Sessionals : 25 Nature of Exam :Seminar

    1. A report to be submitted on the topic suggested by the Department. 2. Credit for report : 10 marks 3. Credit for Seminar talk : 15 marks