5 - 6 November 2012Baltimore, MD, USA

International Workshop on HIV & Aging3rd

INVITATIONOrganizing Committee

CME Accreditation

Learning Objectives

Registration, Additional Information

www.virology-education.com

At the conclusion of this activity, the participants should be able to: - Identify age related clinical complications found in the aging

HIV-infected patient - Integrate the latest scientific research into daily clinical care to

improve the quality of life of these patients - Identify the future challenges faced by this expanding population of

elderly HIV infected patients

The target audience of this meeting consists of internal Medicine specialists (clinicians working in cardiovascular, renal, endocrine, and metabolic complications of HIV areas), infectious disease specialists, (virologists, immunologists, pharmacologists), geriatricians, neurologists, epidemiologists, geneticists and other clinical researchers.

Charles Boucher, MD, PhD

Erasmus University Rotterdam, the Netherlands

William Ershler, MD

IASIA, USA

Russell Tracy, PhD

University of Vermont, USA

Jules Levin, MS

NATAP, USA

Jonathan Schapiro, MD

Sheba Medical Center, Israel

Susan Resnick, PhD

National Institutes of Health / National Institute of Aging, USA

Charles Flexner, MD (co-chair 2012)

Johns Hopkins University School of Medicine, USA

Scott Letendre, MD (co-chair 2012)

University of California, San Diego,USA

Jacqueline Capeau, MD, PhD (guest co-chair 2012)

INSERM, France

The annual international Workshop on HIV & Aging was initiated three years ago as a unique and much needed platform for international scientific exchange on the increasingly recognized problems of HIV and aging. As in previous years, the 2012 edition will gather a cross-disciplinary team of experts and trainees involved in HIV and aging research, in order to present and discuss the latest developments and strategies for the future, in an interactive and science - focused setting.

The meeting will have a two day program consisting of invited lectures, abstract-driven scientific presentations and poster sessions. The latest developments will be reviewed and evaluated in order to identify important topics for future research, develop better approaches to treatment, and create a strategic agenda for future management problems associated with HIV and aging. This workshop is intended as a small, focused meeting to encourage scientific dialogue among all attendees, including presenters.

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the University ofCalifornia, San Diego School of Medicine and Virology Education. The University of California, San Diego School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of California, San Diego School of Medicine designates this live activity for a maximum of 15.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. AMA PRA Category 1 Credit are recognized by the European Accreditation Council for Continuing Medical Education (EACCME) towards EACCME credits. To convert AMA PRA category 1 credits to EACCME credit, contact the EACCME office.

Joint Sponsor:

Cultural and Linguistic Competency StatementThis activity is in compliance with California Assembly Bill 1195 which requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. Cultural competency is defined as a set of integrated attitudes, knowledge, and skills that enables health care professionals or organizations to care effectively for patients from diverse cultures, groups, and communities. Linguistic competency is defined as the ability of a phy-sician or surgeon to provide patients who do not speak English or who have limited ability to speak English, direct communication in the patient’s primary language. Cultural and linguistic competency was incorporated into the planning of this activity. Additional resources on cultural and linguistic competency and information about AB1195 can be found on the UCSD CME website at http://cme.ucsd.edu.

Disclosure StatementIt is the policy of the University of California, San Diego School of Medicine to ensure balance, independence, objectivity and scientific rigor. All persons involved in the selection, development and presentation of content are required to disclose any real or apparent conflicts of interest. All conflicts of interest will be resolved prior to an educational activity being delivered to learners through one of the following mechanisms 1) altering the financial relationship with the commercial interest, 2) altering the individual’s control over CME content about the products or services of the commercial interest, and/or 3) validating the activity content through independent peer review. All persons are also required to disclose any discussions of off label/unapproved uses of drugs or devices. Persons who refuse or fail to disclose will be disqualified from participating in the CME activity.

Target Audience

Program

Tuesday 6 November 2012

Session 5 – Successful aging

08:30h General overview of aging as multi-system failure Anne Newman, MD, PhD, University of Pittsburg, Pittsburg, USA

09:00h Lifestyle variables and age-related cognitive changes Robert Wilson, PhD, Rush University Medical Centre, Chicago, USA

09:30h Neuropathology of aging Steven Arnold, MD, University of Pennsylvania, Pennsylvania, USA

10:00h The LIFE trial Marco Pahor, MD, University of Florida, Gainesville, USA

10:30h Discussion11:00h Coffee Break

Session 6 Aging in the human Liver

11:30h Invited lecture: Protein synthesis and the aging liverRussell Tracy, PhD, University of Vermont, Burlington, USA

12:00h Invited lecture: Accelerated CirrhosisDavid Thomas, MD, MPH, Johns Hopkins University, Baltimore, USA

12:30h Clin. Case: Accelerated Cirrhosis Douglas Dieterich, MD, Mount Sinai Medical Centre, New York, USA

13:00h Lunch

Session 7 Clinical Case Session / Clinical implications14:00h Clinical case presentation

Kelly Gebo, MD, MPH, Johns Hopkins University, Baltmore, USA

14:30h Clinical case presentation Cynthia Boyd, MD, MPH, Johns Hopkins University, Baltmore, USA

15.00h Abstract – driven presentations15.30h Discussion

16:00h Coffee break

Session 7 Multi-morbidity Aging Cohorts16:30h Invited lecture

Giovanni Guaraldi, MD, Policlinico Modena, Modena, Italy

17:00h Invited lecture Amy Justice, MD, PhD, Yale School of Medicine, New Haven, USA

17.30h Discussion

18.00h Closure of the workshop

Monday 5 November 2012

09:00h Opening of the Workshop

Session 1 - Senescence

09:15h Invited lecture: Immune Senescence Victor Appay, PhD, INSERM, Paris, France

09:45h Invited lecture: Cell Senescence Norman Sharpless, MD, UNC School of Medicine, Chapel Hill USA

10:15h Discussion Panel Member: Seema Desai, PhD, Rush University Medical Centre, Chicago, USA

10:45h Coffee Break

Session 2

11:15h Abstract – Driven Presentations

13:00h Lunch

Round table discussion: Mitochondrial damage/ toxicity

14:00h Invited lecture: Role of the virus Hélène Coté, PhD, University of Vancouver, Vancouver, Canada

14:30h Invited lecture: Role of genetics Andrea Cossarizza, MD, PhD, Policlinico Modena, Modena, Italy

15.00h Invited lecture: Role of the treatmentPatrick Mallon, PhD, University College Dublin, Dublin, ireland

15.30h Discussion

16:00h Coffee break

Session 4

16:45h Abstract - driven presentations

18:00h Adjournment

19.00h Workshop Dinner

This conference promises to be a high profile scientific meeting with the contribution of key opinion leaders. We are proud to present the preliminary program: