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Holarrhena antidysentericaHolarrhena antidysentericaApocynaceae
Collection
• Obtained from wild sources
• Collected from plants of 8-12 yrs old
• Longitudinal & transverse incisions are made in the trunk from July – Sept
Description
• Shape recurved
• Surface buff / brownish colour
shows deep cracks
longitudinally wrinkled
• Odourless
• Taste bitter
• Fracture short , granular , splintery
Microscopy • Cork tangentially & radially elongated • Cork cambium present in several layers• Cortex stone cellsstone cells single/groups horizontal layers
Phloem fibersPhloem fibers absent
ParenchymaParenchyma encircle stone cells & also contain starch
• Medullary rays multiseriate
Widen towards outer side
In between them stone cells & calcium oxalate present
Constituents
• Steroidal alkaloids
Conessine
Norconessine
Isoconessine
Kurchine
Uses Uses • Antiprotozoal in the treatment of amoebic
dysentery