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sonography must be performed in order to evaluate associated anomaly of heart, vertebra, gastrointestinal tract or other organs. 3424 Extrarenal anomalies associated with fetal renal dysplasia Choi SJ, Kim YH, Choi JY, Song SY, Kim SA, Song CH, Jung H, Department of Obstetrics and Gynecology, Chosun University hospital, Korea; Department of Radiology, Chosun University hospital, Korea Objectives: The fetal renal dysplasia is relatively easily detectable anomalies in antenatal sonography. The purpose of this study is to evaluate other anomalies associated with the fetal renal dysplasia. Methods: This was a follow-up study of fetal renal dysplasia detected antenatally in level II sonography between 1998 and 2005. Thirty-one fetuses who have fetal renal dysplasia detected by antenatal sonography were evaluated after delivery and termination. We excluded the cases of hydronephrosis and contralateral renal pelvis dilatation. Results: There were two cases of polycystic kidney, four cases of bilateral renal agenesis, four cases of unilateral renal agenesis, three cases of bilateral multicystic dysplastic kidney and 18 cases of unilat- eral multicystic dysplastic kidney. The most common associated anom- aly was congenital heart disease (eight cases). Single umbilical artery was seven cases, imperforate anus was four cases, tracheo-esophageal fistula was two cases. Other anomalies were contralateral renal cortical dysplasia, contralateral pelvic kidney, hypospadia and scoliosis with hemivertebra. Conclusions: Fetal echocardiography must be performed in order to evaluate associated cardiac anomaly if fetal renal dysplasia is detected antenatally by sonography. 3425 Intrauterine diagnosis and management of congenital goitrous hypothyroidism in one of dizygotic twin pregnancy Lee PR, Won H-S, Shim J-Y, Kim A, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea We present a case of fetal congenital goitrous hypothyroidism in one of dizygotic twin pregnancy. A routine ultrasound examination at 20 weeks of gestation revealed a bilobed large fetal neck mass in the first twin. There was neither other abnormal finding nor polyhydramnios. Cordocentesis was performed to evaluate fetal thyroid function and congenital hypothyroidism was confirmed. The other fetus was normal. We administered intra-amniotic thyroxin (200 ug) injection three times, at 23, 24 and 25 weeks. Follow-up cordocentesis revealed euthyroid status; although the thyroid gland had decreased in size, it was still goitrous. The mother was proved to have subclinical hypothyroidism and started synthroid treatment. At 36 weeks of gestation, PPROM occurred and the twins were delivered vaginally. The first twin was proved as an euthyroid status with no need for further treatment. 3426 Harlequin ichthyosis misdiagnosed as bilateral cleft lip on prenatal sonography in a twin conceived by in vitro fertilization Park Y-N, Moon S-O, Kim HA, Choi S-J, Oh S-Y, Kim J-H, Samsung Medical Center Sungkyunkwan University School of Medicine, Korea Objectives: Harlequin ichthyosis is a severe and fatal form of congen- ital ichthyosis and has an autosomal recessive inheritance. Methods: We report a case of harlequin ichthyosis misdiagnosed as bilateral cleft lip on prenatal sonography in a twin conceived by IVF. Results: Case: A 36-year-old women, with twin pregnancy, who con- ceived by IVF was referred. The ultrasound performed at 28 weeks gestation suspected bilateral cleft lip and palate, rocker bottom feet and hydronephrosis in left kidney in fetus A. Because her pregnancy was complicated by PPROM at 34 weeks of gestation, emergency Cesarean section was done and the neonate A was found to have severe ichthy- osis involving whole body with large plaques of hyperkeratotic skin on palms and soles, and the neonate B was normal. The neonate A had a flat and hypoplastic nose, a large mouth that was widely gaping open, an ectropion, abnormal fixed position of the hands and edema of thighs and feet. Conclusions: Here we present a harlequin ichthyosis case misdiag- nosed as bilateral cleft lip on 2D ultrasound. Because this lethal condition is inherited by autosomal recessive trait, molecular gene test and meticulous ultrasound examination in 3D as well as conventional 2D should be offered at her next pregnancy. 3427 Clinical application and usefulness of multi-slice view in fetal echocardiography Won H-S, Kim S-K, Shim J-Y, Lee PR, Kim A, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea Objectives: To introduce the clinical application and usefulness of multi-slice view (MSV) for screening of fetal heart anomalies. Methods: We performed prenatal ultrasonography with Accuvix XQ 3D probe (Medison Co. Korea) in Asan Medical Center between June 2004 and October 2005. Thirty-five fetuses with congenital heart anom- alies at various gestational ages were investigated. Results: We obtained abnormal views of 35 fetuses using MSV. The MSV provided excellent views of great vessel alignment and different types of septal defects. Conclusions: The 3D-XI is an innovative diagnostic tool that incor- porates CT- and MRI-like technologies with ultrasound. 3D-XI pro- vides additional information in fetal echocardiography, particularly regarding the alignment of great vessels and mapping of septal defects. The data selection and storage functions permit faster and more accu- rate diagnoses. 3428 Ovarian hyperstimulation syndrome: Clinical review and ultrasonographic findings Yoon SK, Cho JH, Oh JY, Choi JC, Nam KJ, Kang M-J, Lee JH, Shin TB, Choi S-S, Lee KN, Han MS, Dong-A University College of Medicine, Korea The incidence of ovarian hyperstimulation syndrome (OHSS) follow- ing controlled ovarian hyperstimulation for in vitro fertilization and embryo transfer (IVF-ET) varies from 0.005% to 7% in the moderate form and from 0.008% to 1.9% in the severe form. The purpose of this study was to review OHSS and evaluate US findings, including Dopp- ler study, in patients with moderate or severe OHSS. We performed gray-scale and Doppler US in each case of OHSS. In conclusion, gray-scale and Doppler US are useful in evaluating the size of ovaries, the number of ovarian cysts, internal echogenicity and Doppler param- eters of the ovarian stromal and uterine arteries in moderate or severe OHSS following controlled ovarian hyperstimulation for IVF-ET. 3429 Sonographic diagnosis of an incomplete uterine rupture Fan Y, The 2nd HuaXi Hospital, SiChuan University, China A 34-year-old woman who had Cesarean section 5 years ago, presented with vaginal bleeding at 26 weeks gestation. At 31 weeks of gestation, hypoechoic zone with a width of 1.6 cm and no blood flow signal was depicted on CDFI under the serous membrane of the lower part of anterior wall. The patient had Cesarean section at the same day. Abstracts P263

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sonography must be performed in order to evaluate associated anomalyof heart, vertebra, gastrointestinal tract or other organs.

3424

Extrarenal anomalies associated with fetal renal dysplasiaChoi SJ, Kim YH, Choi JY, Song SY, Kim SA, Song CH, Jung H,Department of Obstetrics and Gynecology, Chosun Universityhospital, Korea; Department of Radiology, Chosun Universityhospital, Korea

Objectives: The fetal renal dysplasia is relatively easily detectableanomalies in antenatal sonography. The purpose of this study is toevaluate other anomalies associated with the fetal renal dysplasia.Methods: This was a follow-up study of fetal renal dysplasia detectedantenatally in level II sonography between 1998 and 2005. Thirty-onefetuses who have fetal renal dysplasia detected by antenatal sonographywere evaluated after delivery and termination. We excluded the casesof hydronephrosis and contralateral renal pelvis dilatation.Results: There were two cases of polycystic kidney, four cases ofbilateral renal agenesis, four cases of unilateral renal agenesis, threecases of bilateral multicystic dysplastic kidney and 18 cases of unilat-eral multicystic dysplastic kidney. The most common associated anom-aly was congenital heart disease (eight cases). Single umbilical arterywas seven cases, imperforate anus was four cases, tracheo-esophagealfistula was two cases. Other anomalies were contralateral renal corticaldysplasia, contralateral pelvic kidney, hypospadia and scoliosis withhemivertebra.Conclusions: Fetal echocardiography must be performed in order toevaluate associated cardiac anomaly if fetal renal dysplasia is detectedantenatally by sonography.

3425

Intrauterine diagnosis and management of congenital goitroushypothyroidism in one of dizygotic twin pregnancyLee PR, Won H-S, Shim J-Y, Kim A, University of Ulsan College ofMedicine, Asan Medical Center, Seoul, Korea

We present a case of fetal congenital goitrous hypothyroidism in one ofdizygotic twin pregnancy. A routine ultrasound examination at 20weeks of gestation revealed a bilobed large fetal neck mass in the firsttwin. There was neither other abnormal finding nor polyhydramnios.Cordocentesis was performed to evaluate fetal thyroid function andcongenital hypothyroidism was confirmed. The other fetus was normal.We administered intra-amniotic thyroxin (200 ug) injection three times,at 23, 24 and 25 weeks. Follow-up cordocentesis revealed euthyroidstatus; although the thyroid gland had decreased in size, it was stillgoitrous. The mother was proved to have subclinical hypothyroidismand started synthroid treatment. At 36 weeks of gestation, PPROMoccurred and the twins were delivered vaginally. The first twin wasproved as an euthyroid status with no need for further treatment.

3426

Harlequin ichthyosis misdiagnosed as bilateral cleft lip onprenatal sonography in a twin conceived by in vitro fertilizationPark Y-N, Moon S-O, Kim HA, Choi S-J, Oh S-Y, Kim J-H, SamsungMedical Center Sungkyunkwan University School of Medicine, Korea

Objectives: Harlequin ichthyosis is a severe and fatal form of congen-ital ichthyosis and has an autosomal recessive inheritance.Methods: We report a case of harlequin ichthyosis misdiagnosed asbilateral cleft lip on prenatal sonography in a twin conceived by IVF.Results: Case: A 36-year-old women, with twin pregnancy, who con-ceived by IVF was referred. The ultrasound performed at 28 weeksgestation suspected bilateral cleft lip and palate, rocker bottom feet and

hydronephrosis in left kidney in fetus A. Because her pregnancy wascomplicated by PPROM at 34 weeks of gestation, emergency Cesareansection was done and the neonate A was found to have severe ichthy-osis involving whole body with large plaques of hyperkeratotic skin onpalms and soles, and the neonate B was normal. The neonate A had aflat and hypoplastic nose, a large mouth that was widely gaping open,an ectropion, abnormal fixed position of the hands and edema of thighsand feet.Conclusions: Here we present a harlequin ichthyosis case misdiag-nosed as bilateral cleft lip on 2D ultrasound. Because this lethalcondition is inherited by autosomal recessive trait, molecular gene testand meticulous ultrasound examination in 3D as well as conventional2D should be offered at her next pregnancy.

3427

Clinical application and usefulness of multi-slice view in fetalechocardiographyWon H-S, Kim S-K, Shim J-Y, Lee PR, Kim A, University of UlsanCollege of Medicine, Asan Medical Center, Seoul, Korea

Objectives: To introduce the clinical application and usefulness ofmulti-slice view (MSV) for screening of fetal heart anomalies.Methods: We performed prenatal ultrasonography with Accuvix XQ3D probe (Medison Co. Korea) in Asan Medical Center between June2004 and October 2005. Thirty-five fetuses with congenital heart anom-alies at various gestational ages were investigated.Results: We obtained abnormal views of 35 fetuses using MSV. TheMSV provided excellent views of great vessel alignment and differenttypes of septal defects.Conclusions: The 3D-XI is an innovative diagnostic tool that incor-porates CT- and MRI-like technologies with ultrasound. 3D-XI pro-vides additional information in fetal echocardiography, particularlyregarding the alignment of great vessels and mapping of septal defects.The data selection and storage functions permit faster and more accu-rate diagnoses.

3428

Ovarian hyperstimulation syndrome: Clinical review andultrasonographic findingsYoon SK, Cho JH, Oh JY, Choi JC, Nam KJ, Kang M-J, Lee JH,Shin TB, Choi S-S, Lee KN, Han MS, Dong-A University College ofMedicine, Korea

The incidence of ovarian hyperstimulation syndrome (OHSS) follow-ing controlled ovarian hyperstimulation for in vitro fertilization andembryo transfer (IVF-ET) varies from 0.005% to 7% in the moderateform and from 0.008% to 1.9% in the severe form. The purpose of thisstudy was to review OHSS and evaluate US findings, including Dopp-ler study, in patients with moderate or severe OHSS. We performedgray-scale and Doppler US in each case of OHSS. In conclusion,gray-scale and Doppler US are useful in evaluating the size of ovaries,the number of ovarian cysts, internal echogenicity and Doppler param-eters of the ovarian stromal and uterine arteries in moderate or severeOHSS following controlled ovarian hyperstimulation for IVF-ET.

3429

Sonographic diagnosis of an incomplete uterine ruptureFan Y, The 2nd HuaXi Hospital, SiChuan University, China

A 34-year-old woman who had Cesarean section 5 years ago, presentedwith vaginal bleeding at 26 weeks gestation. At 31 weeks of gestation,hypoechoic zone with a width of 1.6 cm and no blood flow signal wasdepicted on CDFI under the serous membrane of the lower part ofanterior wall. The patient had Cesarean section at the same day.

Abstracts P263