3 IEEE International Conference on Biomedical and Health ...bhi.embs.org/2016/wp-content/uploads/sites/26/2015/...Nenad Filipovic, University of Kragujevac ix. REVIEWERS 3rd IEEE International

3rd IEEE International Conference on Biomedical and Health Informatics

24-27 February 2016

Westin Hotel Las Vegas Hotel - Casino & Spa

Conference Co-Chairs Program Co-Chairs

Stephen Wong Ilkka Korhonen

Conference Co-Chairs Program Co-Chairs

Elliot Sloane May D. Wang


Editor’s Note .................................................................................................................................................... iv

IEEE Engineering in Medicine and Biology .................................................................................................... v

Organizing Committee .................................................................................................................................. vi

Reviewers ........................................................................................................................................................ viii

Welcome Letter ............................................................................................................................................. xvi

Conference Partners .................................................................................................................................... xvii

General Information .................................................................................................................................... xviii

Program at a Glance ................................................................................................................................... xix

Plenary & Keynote Speakers ....................................................................................................................... xxv

Invited Panel Speakers ................................................................................................................................ xxx

Program in Chronological Order ................................................................................................................ 1

Author Index ................................................................................................................................................... 15

Floor Plan ......................................................................................................................................................... 22

TABLE OF CONTENTS

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The 3rd IEEE EMBS International Conference on Biomedical & Health Informatics (BHI’16) of the IEEE Engineering in Medicine and Biology Society hosted an electronic paper submission process for the conference. It was the responsibility of the submitting Author to ensure the document was viewable and without errors that would prevent the Conference from including the paper in the Digital Proceedings or Website. In the event a paper was submitted that could not be viewed or printed properly, the Conference elected to only publish the abstract of the paper in the Proceedings.

All conference papers were peer-reviewed by experts chosen by the BHI Conference Editorial Board for all contributed and Special Session papers.

EDITOR’S NOTE

iv


The Engineering in Medicine and Biology Society of the IEEE advances the application of engineering sciences and technology to medicine and biology, promotes the profession, and provides global leadership for the benefit of its members and humanity by disseminating knowledge, setting standards, fostering professional development, and recognizing excellence. The EMBS field of interest is the development and application of engineering concepts and methods to biology, medicine and health sciences to provide effective solutions to biological, medical and healthcare problems. The field encompasses the development of mathematical theories, physical, biological and chemical principles, computational models and algorithms, devices and systems for clinical, industrial and educational applications.

PUBLICATIONS

IEEE PULSE: A Magazine of the IEEE Engineering in Medicine and Biology Society Transactions on Biomedical Engineering Journal of Biomedical Health and Informatics Transactions on Neural Systems and Rehabilitation Engineering Transactions on Medical Imaging Transactions on NanoBioscience

Transactions on Computational Biology and Bioinformatics Transactions on Biomedical Circuits and Systems Reviews on Biomedical Engineering IEEE Journal on Translational Engineering in Health & Medicine

IEEE Transaction on Computational Imaging IEEE Lifesciences Letters

ELECTRONIC PRODUCTS EMBS Electronic Resource

CONFERENCES Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

IEEE EMBS Special Topic Conference on Neural Engineering (NER) International Symposium on Biomedical Imaging (ISBI)

International Conference on Biomedical Robotics and Biomechatronics (BIOROB) International Conference on Rehabilitation Robotics (ICORR)

Healthcare Innovation and Point of Care Technologies Conference (HICPT) EMBS Micro and Nanotechnology in Medicine (MNM)

Grand Challenges Conference Series (GCBE) IEEE EMBS International Conference on Biomedical and Health Informatics (BHI)

SUMMER SCHOOLS Technically Co-Sponsored by EMBS International Summer School on Biomedical Imaging

International Summer School on Biomedical Signal Processing International Summer School on Biocomplexity

International Summer School on Information Technology in Biomedicine International Summer School on Emerging Technologies and Applications in Telemedicine:

Addressing the Challenges of Chronic Disease Management International Summer School on Neural Engineering (ISSNE)

Engineering in Medicine and Biology Society 445 Hoes Lane, Piscataway, New Jersey, USA 08854

Telephone: +1 732 981 3433, E-mail: [email protected] www.embs.org

IEEE ENGINEERING IN MEDICINE & BIOLOGY

v

ORGANIZING

COMMITTEE


CONFERENCE CO-CHAIRS Stephen Wong- PhD, EMBS Biomedical and Health Informatics Technical Committee (BHI-TC)

Chair, Houston Methodist Research Institute, Weill Cornell Medical College Elliot Sloane- PhD, HIMSS-Appointed Director to Integrating the Healthcare Enterprise (IHE)

International and IHE USA, Villanova Univ.

PROGRAM CHAIRS Ilkka Korhonen- PhD, EMBS BHI Steering Committee (BHI-SC) Member,

Tampere Univ. of Technology, Finland May D. Wang- PhD, Chair, EMBS Biomedical and Health Informatics Technical Committee and

BHI Steering Committee Chair, Georgia Institute of Technology and Emory University, USA

WORKSHOP & SPECIAL SESSION CO-CHAIRS Misha Pavel- Northeastern University

Dimitris I. Fotiadis- University of Ioannina, Greece

BHI ADVISORY COMMITTEE Andrew Laine- PhD, EMBS President, Columbia Univ., USA

Metin Akay- PhD, EMBS Book Series Editor-in-Chief (EiC), Univ. of Houston, USA Jose Principe- PhD, EMBS Vice President of Technical Activities, Univ. of Florida, USA

BHI STEERING COMMITTEE Paolo Bonato- PhD, EMBS Vice President of Publications, Harvard Univ., USA

Ratko Magiarevic- PhD, IFMBE Past President and ICBHI’2015 Co-Chair, Univ of Zagreb, Croatia Carolyn McGregor- AM, PhD, EMBS, IEEE Life Science Technical Community Vice Chair,

Univ. of Ontario Institute of Technology, Canada Konstantina S. Nikita- MD/PhD, EMBS Journal of Biomedical and Health Informatics (JBHI)

Associate Editor (AE), National Technical Univ. of Athens, Greece May D. Wang- PhD, BHI Steering and Technical Committees Chair,

Georgia Institute of Technology and Emory Univ., USA Bruce Wheeler- PhD, IFMBE ICBHI’2015 Co-Chair, Univ. of California San Diego, USA

Guang-Zhong Yang- PhD, EMBS Journal of Biomedical and Health Informatics (JBHI) Editor-in-Chief (EiC), Imperial College, UK

Yuan-Ting Zhang- PhD, IFMBE ICBHI’2015 Chair, The Chinese Univ. of Hong Kong, Hong Kong

CONFERENCE EDITORIAL BOARD Dimitrios I. Fotiadis- University of Ioannina, Greece Omer Inan- Georgia Institute of Technology, USA

Jie Liang- University of Illinois at Chicago, USA Benny Lo- Imperial College London, UK

Christopher Nugent- Ulster University, Northern Ireland vi

ORGANIZING COMMITTEE


Bahram Parvin- University of Nevada, USA Constantinos S. Pattichis- University of Cyprus, Cyprus

Stephen Redmond- University of New South Wales, Australia Bruce Schatz- University of Illinois, Urbana-Champaign, USA

Elliot Sloane- Villanova University, USA Mark van Gils- VTT Technical Research Centre of Finland, Finland

Alistair Young- University of Auckland, New Zealand

INTERNATIONAL PROGRAM COMMITTEE Chang Joseph- Ph.D., National University of Singapore, Singapore

Albert C. S. Chung- Ph.D., University of Science and Technology of Hong Kong, HK, P R China Wai-Chi Fang- Ph.D., National Chiao Tung University, Taiwan, ROC

Juan M Garcia-Gomez- Ph.D. Polytechnic University of Valencia, Spain Bin He- Ph.D., University of Minnesota, USA

Hai Li- Ph.D., Chinese Academy of Sciences, Hefei, P R China Oscar Pastor- Ph.D., Universidad Politécnica de Valencia, Spain

Constantinos Pattichis- Ph.D., University of Cyprus, Cyprus Mohamad Sawan- Ph.D., Polytechnique Montreal, Canada Mark van Gils- Ph.D. VTT Technical Research Centre, Finland

Maria Teresa Arredondo Waldmeyer- Ph.D., Universidad Politecnica de Madrid, Spain Jianguo Zhang- Ph.D., Chinese Academy of Sciences, Shanghai, P R China

Paulo Carvalho- Ph.D., Universidade De Coimbra, Portugal Kangping Lin- Ph.D., Chung-Yuan Christian University, Taiwan

Marc Nyssen- Ph.D., Vrije Universiteit Brussel, Belgium Ewa Piêtka- Ph.D., Silesian University of Technology, Poland

Bensheng Qiu- Ph.D., The University of Science and Technology in China, P.R. China Jianwen Luo- Ph.D., Department of Biomedical Engineering, Tsinghua University, Beijing, China

Zuhong Lu- Professor, Peking University and Southeast University Elsa D Angelini- Ph.D., Columbia University, USA

EMBS EXECUTIVE OFFICE Jessica Lotito- CMP, Manager, Conference Services, EMBS

Laura Wolf- CMM, Executive Director, EMB

vii

REVIEWERS


Niki Abolhassani, AFrame Digital Inc. Jose Abraham, Kimberly Clark Naveed Afzal, Mayo Clinic Rochester MN Alireza Ahmadian, Tehran University of Medical Sciences Alvaro Alesanco, University of Zaragoza Ali Hussian Ali, Baghdad University Sonya Allin, University of Toronto Rute Almeida, Faculty of Science of the University of Porto Miguel Altuve, Pontifical Bolivarian University Daniel Álvarez, University of Valladolid, CIF: Q4718001C Guanglei An, Oklahoma State University Björn Andersen, Universität zu Lübeck Takeshi Ando, Panasonic Corporation Daniel Andresen, Kansas State University Elsa Angelini, Columbia University Alvaro Araujo, Technical University of Madrid Masahiro Aruga, Teikyo Heisei University Farzad Asgarian, K.N.Toosi University of Technology Hazar Ashouri, Georgia Institute of Technology Katherine August, Stevens Institute of Technology Ari-Matti Auvinen, Helsinki University of Technology Dragana Bajic, University of Novi Sad Gabriella Balestra, Politecnico di Torino Riccardo Barbieri, MGH-Harvard Medical School-MIT Pierre Barralon, Tecnalia Research & Innovation Senen Barro, University of Santiago de Compostella Riccardo Bellazzi, University of Pavia Marc-Emmanuel Bellemare, Université Paul Cézanne Anna Maria Bianchi, Politecnico di Milano Leonardo Bocchi, Università degli Studi di Firenze, Firenze, Italy Stefano Bonacina, Karolinska Institutet Thirimachos Bourlai, West Virginia University Anca Bucur, Philips Research Europe Dilpreet Buxi, Monash University Israel Byrd, St. Jude Medical Inc Hanqing Cao, Philips Research North America Pablo Casaseca-de-la-Higuera, University of the West of Scotland Alexander James Casson, The University of Manchester Christine Cavaro-Ménard, Université d'Angers Francesca Cecchi, Scuola Superiore Sant'Anna

viii

REVIEWERS


Nattapon Chaimanonart, Biotronik Wenxi Chen, University of Aizu Xian Chen, Yamaguchi University Erkang Cheng, Broncus Medical Hung-Wen Chiu, Taipei Medical University Changmok Choi, Samsung Advanced Institute of Technology Jin-Woo Choi, Louisiana State University Nee-Yin Chou, CW Optics, Inc. Charalambos Chrysostomou, University of Leicester Vaclav Chudacek, Czech Technical University in Prague Malcolm Clarke, Brunel University Ian Cleland, University of Ulster Philippe Comtois, University of Montreal and Montreal Heart Institute Lorenzo Tancredi D'Angelo, Technische Universitaet Muenchen Giuseppe D'Avenio, Istituto Superiore di Sanità Tao Dai, Carleton University Yang Dai, University of Illinois at Chicago Tien-Tuan DAO, University of Technology of Compiegne Justin Dauwels, NTU Paulo de Carvalho, University of Coimbra - NIF: 501617582 Paula de Toledo, Universidad Carlos III de Madrid Danilo Demarchi, Politecnico di Torino Marco Di Rienzo, Fondazione Don Carlo Gnocchi Mark Donnelly, University of Ulster António Dourado, FCTUC, University of Coimbra, VAT PT 501 617582 Qi Duan, NIH Jacques Duchêne, UTT Mariusz Duplaga, Jagiellonian University Medical College David Epstein, University of Warwick Bjoern M Eskofier, Friedrich-Alexander-Universität Erlangen-Nürnberg Justin Ronald Estepp, Air Force Research Laboratory Daniel Evans, Nelson Irrigation Corporation Konstantinos Exarchos, University of Ioannina Themis P. Exarchos, Unit of Medical Tech & Intelligent Info Jesualdo Tomás Fernández-Breis, Universidad de Murcia Angel Fernandez-Leal, A Coruña University Carlos Fernandez-Llatas, Universidad Politecnica de Valencia Jose M. Ferrandez, Universidad Politecnica de Cartagena Vincenzo Ferrari, Universià di Pisa Nenad Filipovic, University of Kragujevac

ix

REVIEWERS


Stanley Finkelstein, University of Minnesota Emma Fortune, Mayo Clinic Dimitrios I. Fotiadis, University of Ioannina Christoph M. Friedrich, Univ. of Applied Science and Arts Dortmund; Dept. of Computer Science Ana Gabriela Gallardo-Hernández, Instituto Mexicano del Seguro Social Leo Galway, University of Ulster Fan Gao, UT Southwestern Medical Center at Dallas Julio Garcia, Northwestern University Maria Garcia, University of Valladolid, CIF: Q4718001C Jose Garcia Moros, University of Zaragoza Bao GE, Shaanxi Normal University Cyril Gobinet, Université de Reims Champagne Rafael C. Gonzalez, Universidad de Oviedo Barry R. Greene, Kinesis Health Technologies Mauro Grigioni, Istituto Superiore di Sanità Carmen Grigoras, Univ. of Medicine & Pharmacy, Inst. of Computer Science of Romanian Academy Enrico Grisan, University of Padova Cuntai Guan, Institute for Infocomm Research Gamze Gursoy, University of Illinois at Chicago Leontios Hadjileontiadis, Aristotle University of Thessaloniki Dieter Hayn, AIT Austrian Institute of Technology Tiancheng He, Methodist Hospital Research Institute, Weill Cornell Medical College, Cornell Univ. Elina Helander, Tampere University of Technology Jorge Henriques, University of Coimbra - NIF 501617582 Pawel Herman, Royal Institute of Technology Enrique Hernandez-Matos, UAM-Iztapalapa Nidiyare Hevia-Montiel, Universidad Nacional Autonoma de Mexico Kenneth Hoffmann, University at Buffalo Paul Honeine, Université de Rouen Chenhui Hu, Harvard University Sijung Hu, Loughborough University Donna L Hudson, University of California, San Francisco Jari Hyttinen, Tampere University of Technology Jorge Igual Garcia, Universidad Politecnica Politecnica Omer Inan, Georgia Institute of Technology Bart Jansen, Vrije Universiteit Brussel Abdul Qadir Javaid, Georgia Institute of Technology Juan Ramon Jimenez-Alaniz, Universidad Autonoma Metropolitana Zhanpeng Jin, Binghamton University, SUNY Emil Jovanov, University of Alabama in Huntsville

x

REVIEWERS


Martti Juhola, University of Tampere Timo Jämsä, University of Oulu Aravind Kailas, Algorithms, Models, and Systems Solutions, LLC Norhaslinda Kamaruddin, MARA University of Technology Alan D. Kaplan, Lawrence Livermore National Laboratory Evy Karavatselou, University of Patras Walter Karlen, ETH Zurich Peter Kastner, AIT Austrian Institute of Technology Heba Khamis, University of Western Sydney Masood Mehmood Khan, Curtin University Ahsan Habib Khandoker, Khalifa University of Science, Technology and Research Artem Khmelinskii, Instituto Superior Técnico University Jinman Kim, University of Sydney Jun Kong, Emory University George Kontaxakis, Universidad Politécnica de Madrid Ilkka Korhonen, Tampere University of Technology Vassilis Koutkias, INSERM Marek Kretowski, Bialystok University of Technology Tomohiro Kuroda, Kyoto University Andrew Lang, Johns Hopkins University Carole Lartizien, CNRS UMR5220, INSERM U1044, INSA Lyon, Université de Lyon Phooi Yee Lau, Instituto de Telecomunicações Ron Leder, Universidad Nacional Autonoma de Mexico Chang Won Lee, Samsung R&D Institute America - Dallas Jiann-Der Lee, Chang Gung University Khuan Y. Lee, Universiti Teknologi MARA Fedor Lehocki, Slovak University of Technology, Fac. of Electrical Eng. Lenka Lhotska, Czech Technical University in Prague Chengwei Li, Harbin Institute of Technology Fuhai Li, Weill Cornell University - The Methodist Hospital Research Institute Jintao Li, City University of Hong Kong Shuo Li, Stony Brook University Jie Liang, University of Illinois at Chicago Ruizhi Liao, Massachusetts Institute of Technology Chin-Teng Lin, National Chiao-Tung University Meishan Lin, University of Illinois at Chicago Jianbo Liu, Dept. of Defense Biotech. High Performance Computing Software App. Inst. (BHSAI) Benny Lo, Imperial College London Jinglei Lv, Northwestern Polytechnical University, China; The University of Georgia Dimitrios Lymberopoulos, University of Patras

xi

REVIEWERS


Said Mahmoudi, Faculty of Engineering of Mons José Alberto Maldonado, Polytechnical University of Valencia Jan Margeta, INRIA Sophia Antipolis Thibault Marin, Illinois Institute of Technology Jorge Alberto Marquez, UNAM-CCADET Antonio Martínez-Millana, Universidad Politécnica de Valencia Ørjan G Martinsen, University of Oslo Georgios Matis, University of Zurich George K Matsopoulos, Inst of Comm & Computer Systems Philippe Mavoungou, CLCC Rene Gauducheau Michael James McGrath, Intel Ireland Ltd Carolyn McGregor, Univ of Ontario Inst of Technology Marco Melo, Universidade de São Paulo USP Lyudmila Mihaylova, University of Sheffield Mas Sahidayana Mohktar, Faculty of Engineering David Moner, Technical University of Valencia Mohsen Moslehpour, Michigan State University Stavroula Mougiakakou, University of Bern Jens Muehlsteff, Philips Arrate Munoz-Barrutia, Universidad Carlos III de Madrid Yuji Murakami, Toyohashi University of Technology Andrew James Narracott, University of Sheffield William Nau, Covidien Herc Neves Hannu Nieminen, Tampere University of Technology Konstantina Nikita, National Technical University of Athens Naotaka Nitta, National Institute of AIST Chris Nugent, University of Ulster Marc Nyssen, VUB Mitsuhiro Ogawa, Teikyo University Alessia Paglialonga, CNR Institute of Biomedical Eng Juha Pajula, VTT Tech Research Centre of Finland Ltd. Theodor Panagiotakopoulos, Hellenic Open University Andreas Panayides, Imperial College Alexandros Pantelopoulos, West Health Institute Costas Papaloukas, University of Ioannina Gianfranco Passariello, Universidad Simón Bolívar Oscar Pastor, Universidad Politécnica de Valencia Timothy Patterson, University of Ulster Constantinos Pattichis, University of Cyprus

xii

REVIEWERS


Misha Pavel, Northeastern University Neil Petroff, Purdue College of Technology - South Bend Tuan D. Pham, Linkoping University Elena Pirogova, RMIT University Carmen CY Poon, The Chinese University of Hong Kong Petre Gavril Pop, Technical University of Cluj Napoca Vassiliki Potsika, Unit of Medical Technology & Intelligent Information Systems, Univ. of Ioannina John Puentes, TELECOM Bretagne - INSERM Sio Hang Pun, University of Macau Juha Pärkkä, Combinostics Harri Pölönen, VTT Tech Research Centre of Finland Ltd. Stephen James Redmond, University of New South Wales James Reuss, Prism Clinical Imaging, Inc. Francisco Rincon, École Polytechnique Fédérale de Lausanne Laura M. Roa, University of Seville Jacob Rosenstein, Brown University Salvador Ruiz-Correa, IPICYT Yoshifumi Saijo, Tohoku University Addisson Salazar Afanador, Universidad Politecnica de Valencia Niilo Saranummi, VTT Technical Research Centre Aydin Saribudak, CCNY Roberto Sassi, Università degli Studi di Milano Mohamad Sawan, Polytechnique Montreal Edward Sazonov, University of Alabama Gerald Schaefer, Loughborough University Bruce Schatz, University of Illinois Boris Schmitz, University Clinic Münster Guenter Schreier, AIT Austrian Institute of Technology GmbH Steffen Schumann, University of Bern, Institute for Surgical Technology and Biomechanics Enzo Pasquale Scilingo, University of Pisa Ralf Seip, Philips Huseyin Seker, The University of Northumbria at Newcastle Saeid Seydnejad, Shahid Bahonar University of Kerman Wenzhe Shi, Imperial College London Ashish Shukla, University of Hawaii V.R. Singh, National Physical Laboratory Marjorie Skubic, University of Missouri Elliot B. Sloane, Center for Healthcare Information Research & Policy (CHIRP) Paolo Soda, Università CAMPUS Bio-Medico Cheong Boon Soh, Nanyang Technological University

xiii

REVIEWERS


Jiahui Song, Wentworth Institute of Technology Chrysostomos Stylios, TEI of Epirus Ronald Summers, Loughborough University Mingui Sun, University of Pittsburgh Jonathan Synnott, University of Ulster Hirofumi Taki, Tohoku University Toshiyo Tamura, Osaka Electro-Communication University Kouhyar Tavakolian, University of British Columbia Wallapak Tavanapong, Iowa State University César Teixeira, University of Coimbra Marcos Telló, Pontificia Univ Católica Wei Tian, University of Illinois at Chicago alessandro tognetti, University of Pisa Gabriella Tognola, IEIIT CNR Antti Tolonen, VTT Tech Research Centre Finland Shuichi Toyoda, Jobu University Vicente Traver, Institute ITACA Carlos Trenado, Freiburg University Neurozentrum Evanthia Tripoliti, University of Ioannina Athanasios Tsalatsanis, University of South Florida Manolis Tsiknakis, ICS-FORTH Markos G. Tsipouras, University of Ioannina Pawel Turcza, AGH University of Science and Technology Harry Tyrer, University of Missouri - Columbia Kazunori Uemura, National Cerebral and Cardiovascular Center Research Institute G. Mihaela Ungureanu, Politehnica University of Bucharest Gaetano Valenza, University of Pisa-MGH-Harvard Medical School Mark van Gils, VTT Tech Research Centre of Finland Ltd. Janani Venugopalan, Georgia Institute of Technology George Verghese, Massachusetts Institute of Technology Dimitrios Ververidis, CERTH Elena Villalba, Centre for the Development of Industrial Technology Giovanni Vozzi, University of Pisa Lorcan Walsh, Novartis Wan Abdul Rahman Wan Harun, SIRIM Berhad Haifeng Wang, Yale University Lei Wang, Shenzhen Institutes of Advanced Technology May D. Wang, Georgia Tech and Emory University Philip A. Warrick, Perigen Canada Bruce Wheeler, University of Florida

xiv

REVIEWERS


Joachim Wiest, cellasys GmbH Seth Wolpert, Penn State University-Harrisburg Stephen Wong, Houston Methodist Research Institute Eung Je Woo, Kyung Hee University Ziyue Xu, National Institutes of Health Rajeev Yadav, Concordia University Byung-Jun Yoon, Texas A&M University Alistair Young, University of Auckland Gudrun Zahlmann, Roche Konstantia Zarkogianni, National Technical University of Athens Michalis Zervakis, Technical University of Crete, Greece Guanqun Zhang, Sotera Wireless Inc. Yingchun Zhang, University of Houston Yong Zhang, Weber State University Jianhua Zhao, University of British Columbia Jieling Zhao, University of Illinois at Chicago Weifan Zheng, North Carolina Central University Fengfeng Zhou, Jilin University Huiyu Zhou, Queen's University Belfast Jian Zhou, Toshiba Medical Research Institute USA, Inc. Jinghao Zhou, University of Maryland Hongjie, Matt Zhu, University of Pennsylvania Min Zhu, University of Oklahoma Reyer Zwiggelaar, Aberystwyth University

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WELCOME MESSAGE


Dear Colleague: We are pleased to welcome you to the 3rd IEEE International Conference on Biomedical Health Informatics. Health Informatics is identified as one of the 14 Grand Challenges of The 21st Century by USA National Academy of Engineering. Biomedical and Health Informatics (BHI) is the interdisciplinary field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving, and decision making, motivated by efforts to improve human health. Therefore, with the healthcare cost surging in almost all nations around the globe, it is critical to speed up the Biomedical and Health Informatics to improve health care with lower cost. The mission of IEEE BHI 2016 is to continually foster this fast growing community by bringing together more academic researchers, clinicians, industrial representatives, research funding agencies, and government policy makers to identify top challenges and priorities, to present high quality research findings, and to share successful stories around the central theme “Integrative informatics for precision and preventive medicine.” This conference is devoted to translational healthcare, specially for precision and preventive medicine, that encompass both the integration and intersection of engineering, medicine, and healthcare, as the realization of innovative and high-impact ideas in healthcare can be better achieved through the involvement of multiple disciplines. This year, BHI 2016 is also co-located with the Healthcare Information and Management Systems Society (HIMSS) Annual Conference & Exhibition in Las Vegas, NV, USA. The conference is organized into six main topics: Health/Medical Informatics, Bioinformatics, Sensor Informatics, Imaging Informatics, Public Health Informatics, and Theoretical Foundation of Informatics. It will cover diverse topics from cutting-edge biomedical and healthcare technology research and development, clinical applications, to biomedical education. We have a superb group of keynote speakers, workshops, special sessions, and oral and poster sessions. A great deal of effort was done to make sure that all sessions are highly interactive and of interest to our participants. We want to take this opportunity to thank the members of various BHI committees. Their hard work created the robust program that you can enjoy in these three days. We would also like to thank all the participants that choose this venue to present their current research work. Networking is one of the most interesting facets of IEEE BHI 2016 conference we have dedicated part of the program to social events that are going to give you a lot of opportunities to make personal contacts. We are looking forward to seeing you in Las Vegas! On behalf of the 2016 IEEE Biomedical Health Informatics Conference Organizing Committee!

Dr. Stephen T. C. Wong Dr. Elliot Sloane BHI 2016 Conference Co- Chair BHI 2016 Conference Co- Chair

xvi

PARTNERS


CONFERENCE SPONSORS

TECHNICAL CO-SPONSOR

COLLABORATOR

xvii

GENERAL INFO


REGISTRATION

Registration is located in the Walkway, Second Floor, and will be open Wednesday, 24 February through Saturday, 27 February. Staff will be able to assist you during the following times.

Wednesday 08:00 – 18:00

Thursday 07:00 – 17:00

Friday 07:30 – 17:00

Saturday 07:30 – 15:00

Attendees must wear their badges at all times to gain access to the conference.

Tickets are available for companions for the Welcome Reception and can be purchased at the registration desk for $75.

LUNCH Attendees are on their own for Lunch each day.

POSTER SESSIONS The posters will be displayed at the first poster session on Wednesday, 24th February and remain up until the last poster session on Friday, 26th February.

INSTRUCTIONS FOR AUTHORS

POSTER PRESENTATION Push pins will be provided to attach your posters to your assigned poster board. Please stay with your poster for the entire session times listed for the poster session each day.

All Boards are to be put up on your assigned board between 08:00 and 12:30 on Wednesday, 24th February and remain up until 16:45 on Friday 26th February.

Poster Session Times for Authors: o Wednesday, 24th February 16:30-16:45

o Thursday, 25th February, 10:15-10:30, 16:30-16:45 & 19:30-21:00

o Friday, 26th February, 10:15-10:30 & 16:30-16:45

GENERAL CONFERENCE INFORMATION

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atic

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sion

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rmat

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eara

ble

tech

nolo

gies

)

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cial

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sion

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rc &

jk

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) (IF

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atko

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jare

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for P

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nalis

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t Con

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eth

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ics

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rass

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from

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6:45

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5 –

18:1

5

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sion

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eore

tical

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form

atic

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orith

ms)

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sion

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agin

g In

form

atic

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re S

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aps

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ndar

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el-4

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olao

s M

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vera

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aulo

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o):

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ance

d S

olut

ions

for S

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ed C

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of M

ultim

orbi

d P

atie

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cial

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sion

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3 (T

om

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lliot

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omp

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omen

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edic

al

and

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lth In

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t Pap

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ay 1

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ion

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ster

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ting

with

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s - H

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e an

d Pu

blis

h Pa

pers

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ng-

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g Ya

ng; E

dwar

d Li

ving

ston

; St

eve

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g et

. al.

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: Aca

cia

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apid

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sion

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sion

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rts

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M)

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peci

al

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sion

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ed.2

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h1r )

(J

ie L

iang

*, H

amm

ad N

avee

d):

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puta

tiona

l Pre

cisi

on M

edic

ine:

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redi

ctio

n of

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cer V

aria

nts

and

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ggab

le S

ites

in P

rote

ins

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cial

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sion

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hu.2

(h

k81r

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ei H

uang

, Ahm

ed

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fik, M

ay D

. Wan

g):

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info

rmat

ics

for P

reci

sion

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edic

ine

(II)

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fee

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ak a

nd P

oste

r Vie

win

g/Vo

ting

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over

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e B

reak

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ter V

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g (R

OO

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alov

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anka

r Sub

ram

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CSD

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eb. 2

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ng O

ppor

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ties

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alla

han,

NC

I; Va

lerie

Flo

ranc

e,

NLM

, Wen

dy N

ilsen

, NSF

;And

reas

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oulo

uldi

s, E

C)

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ropo

sal P

eer-

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iew

(M

ark

Cap

rara

, NIH

CSR

)

(S

essi

on e

nds

at 2

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M)

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sday

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eb. 2

016

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war

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ving

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Dep

uty

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r

(RO

OM

: Aca

cia

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)

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id F

ire S

essi

on

Pan

el-1

(13

iww

):

To

o M

uch

Dat

a To

o Li

ttle

Tim

e:

Pre

ssur

es, P

ract

ice

and

Pos

sibi

litie

s fo

r Use

of B

ig-D

ata

Stra

tegi

es a

nd A

naly

tics

in

Hea

lthca

re(M

arvi

n J.

Sle

pian

*, F

uad

Rah

man

, Akh

sar K

hare

bov,

M

att S

arre

l, S

yed

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sain

y,

from

Clin

ical

Com

mun

ity)

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NFE

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CE

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h B

reak

and

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ter V

iew

ing

(Lun

ch

on o

wn-

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ers

in P

aolv

erde

A&

B)

Lunc

h B

reak

and

and

Pos

ter V

iew

ing

(Lun

ch o

n ow

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ster

s in

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lver

de

A&

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Wel

com

e an

d O

peni

ng R

emar

ks (R

OO

M: A

caci

a A

-C)

Ope

ning

Ple

nary

: Dou

g Fr

idsm

a, A

MIA

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Pre

side

nt

Frid

ay

xix

Mes

quite

2M

esqu

ite 3

Mes

quite

4M

esqu

ite 5

8:00

– 8

:45

8:45

- 9:

15

9:15

– 9:

30

9:30

- 10:

15

10:1

5 –

10:3

0

10:3

0 –

12:0

0

12:0

0 –

12:3

0

12:3

0 - 1

3:00

13:

00 -

13:3

0

13:3

0 - 1

4:15

14:1

5 - 1

5:00

15:0

0 - 1

6:30

16:3

0 - 1

6:45

16:4

5 –

18:1

5

18:1

5 - 1

9:30

19:3

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Clo

sing

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eptio

n (R

OO

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caci

a A

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ksho

p 2

(M

ark

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unst

ein,

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ay D

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g):

Hea

lth In

form

atic

s on

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IR: O

ppor

tuni

ties

in th

e N

ew A

ge o

f In

tero

pera

bilit

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ksho

p - 3

(Faw

zi Be

hman

n, C

elia

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smon

d - I

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mun

icat

ion

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ety)

: Bi

g Da

ta, S

DN, a

nd

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thca

re

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AM -

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00AM

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oria

l-1

Ag

ile M

odel

ing

for A

naly

sis

and

Desig

n of

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omat

ed

Clin

ical

Dec

ision

Sup

port

in

Elec

tron

ic H

ealth

Rec

ords

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0AM

- 12

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M

Tuto

rial-2

(Naj

ah A

l-sha

nabl

eh*)

:

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ta M

inin

g

Tuto

rial-3

(Vija

y G

ehlo

t*, E

lliot

B.

Slo

ane)

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olor

ed P

etri

Net

s B

ased

M

odel

ing

and

Sim

ulat

ion

in H

ealth

care

Lunc

h B

reak

(Lun

ch o

n ow

n)

Wor

ksho

p-1

Con

t. (E

lliot

B. S

loan

e*,

Todd

Coo

per)

:U

nder

stan

ding

How

To

Use

Ope

n S

ourc

e In

tero

pera

bilit

y S

tand

ards

for M

edic

al

Imag

ing,

Dev

ices

, and

R

ecor

ds

Lead

ersh

ip F

orum

: Vis

ion

for B

HI i

n EM

BS

Bes

t Pap

er/P

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r Aw

ard

(R

OO

M: A

caci

a A

-C)

Wor

ksho

p-1

(Elli

ot B

. Sl

oane

*, T

odd

Coop

er):

Und

erst

andi

ng H

ow T

o U

se O

pen

Sour

ce

Inte

rope

rabi

lity

Stan

dard

s for

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ical

Im

agin

g, D

evic

es, a

nd

Reco

rds

Cof

fee

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ak

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eb. 2

016

Day

4

Wor

ksho

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(Lin

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g –

from

M

ICC

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omm

unit y

):

Pat

holo

gy Im

agin

g In

form

atic

s

Wor

ksho

p-4

(Kev

in

Mah

er*,

She

rry

Farr

ugia

, Lea

nne

Wes

t - f

rom

Clin

ical

C

omm

unity

)Tr

ansf

orm

ing

5P

Ped

iatri

c H

ealth

care

by

Tra

ns-D

isci

plin

ary

Hea

lth In

form

atic

s

Clo

sing

Ple

nary

Tal

k (R

OO

M: A

caci

a A

-C)

Rus

s A

ltman

, Sta

nfor

d U

nive

rsity

WO

RK

SHO

PS A

ND

TU

TOR

IALS

Satu

rday

xx

PROGRAM


WEDNESDAY, 24TH FEBRUARY 2016

08:00 – 18:00 Registration Second Floor Walkway

12:30 – 12:45 Opening Ceremony Acacia A-C

12:45 – 13:30 Plenary Speaker - Doug Fridsma, AMIA CEO President

Acacia A-C

13:30 – 14:15 Keynote Speaker - David Mendelson, Mount Sinai Medical Center

Mesquite 3

Session Wed1.1 Theoretical Informatics-1

Mesquite 2

13:30 – 15:00 Panel-1: Too Much Data Too Little Time: Pressures, Practice and Possibilities for Use of Big-Data Strategies and Analytics in Healthcare

Mesquite 4

14:15 – 15:00 Keynote Speaker-Andreas Skoulouldis, European Commission

Mesquite 2

Session Wed2.2 Imaging Informatics-2

Mesquite 3

15:00 – 16:30 Session Wed2.1 Theoretical Informatics-2 (Wearable Technologies)

Mesquite 2


Mesquite 3

Panel-2: Converging Around Big Data and Healthcare, an IEEE BDI Convergence Event

Mesquite 4

16:30 – 16:45 Coffee Break & Poster Session Paloverde A&B

16:45 – 18:15 Session Wed 3.1 Theoretical Informatics-3 (Algorithms)

Mesquite 2


Mesquite 3

Panel-3: From Bench to Bedside to Wellness: Are Standards Gaps Preventing & Hindering Healthcare Innovation at the Point of Care?

Mesquite 4

18:15 – 19:30 Welcome Reception Acacia A-C

19:30 – 21:00 CLOSED MEETING EMBS BHI Steering Committee, BHI Technical Committee, J-BHI Editorial Board Meeting: BHI Growth in EMBS - Opportunities and Lesson Learned

Mesquite 5

xxi

PROGRAM


THURSDAY, 25TH FEBRUARY 2016 07:00 – 17:00 Registration Second Floor Walkway

08:00– 08:45 Plenary Speaker - Shankar Subramaniam, UCSD Acacia A-C

08:45– 10:15 Rapid Fire Session Acacia A-C

10:15– 10:30 Coffee Break & Poster Session Paloverde A&B

10:30– 12:00 Session Thu1.1 Bioinformatics-1

Mesquite 2

Session Thu1.2 Health Informatics-1

Mesquite 3

Special Session-1: Intelligent algorithms for Personalized CVD Management

Mesquite 4

12:30 – 13:30 Lunch Break (on own) & Poster Viewing

12:30 – 14:00 (1) Funding Opportunities (Dan Gallahan, NCI; Valerie Florance, NLM, Wendy Nilsen, NSF; Andreas Skoulouldis, EC) (2) Proposal Peer-Review (Mark Caprara, NIH CSR)

Mesquite 4

13:30 – 14:15 Keynote Speaker - Karl Friedl, UCSF Mesquite 3

Session Thu2.1 Bioinformatics-2

Mesquite 2

14:00 – 15:00 Special Session-2: Computational Precision Medicine: Prediction of Cancer Variants and Druggable Sites in Proteins

Mesquite 4

14:15 – 15:00 Keynote Speaker - Sheng Zhong, UCSD Mesquite 2

Session Thu2.2 Health Informatics-2

Mesquite 3

15:00 – 16:30 Session Thu3.1 Bioinformatics-3

Mesquite 2

Session Thu3.2 Health Informatics-3 (Wearable technologies)

Mesquite 3

Special Session-3: Multi-Parametric Analysis and Information Fusion for Personalized Health

Mesquite 4

16:30 – 16:45 Coffee Break & Poster Session Paloverde A&B16:45 –18:15 Panel-4: Challenges in Health Monitoring and

Analytics in Extreme Environments Mesquite 2

Session Th4.2 Health Informatics-4

Mesquite 3

Special Session-4: Advanced Solutions for Supporting Coordinated Care of Multimorbid Patients with COPD

Mesquite 4

18:15 –19:30 General Assembly and Business Meeting: (1) Report from EMBS BHI Organizing Team (2) Call for 4th BHI Conference Organization

Acacia A-C

19:30 –21:00 Poster Session & Voting Paloverde A&B

xxii

PROGRAM


FRIDAY, 26TH FEBRUARY 2016

07:30 – 17:00 Registration Second Floor Walkway

08:00 – 08:45 Plenary Speaker-Edward Livingston, JAMA Deputy Editor

Acacia A-C

08:45 – 10:15 Rapid Fire Session Acacia A-C

10:15 – 10:30 Coffee Break & Poster Session Paloverde A&B

10:30 – 12:00 Session Fr1.1 Sensor Informatics-1

Mesquite 2

Session Fr1.2 Health Informatics-5

Mesquite 3

Special Session-5: Bioinformatics for Precision Medicine

Mesquite 4

12:30– 13:30 Lunch Break (on own) & Poster Viewing

Meeting with EiCs - How to Write and Publish Papers Mesquite 4

13:30 – 14:15 Keynote Speaker-Michael McCoy, Physician Technology Services, Inc.

Mesquite 3

Session Fr2.1 Sensor Informatics-2

Mesquite 2

13:30 – 15:00 Special Session-6: Bioinformatics for Precision Medicine

Mesquite 4

14:15 – 15:00 Session Fr2.2 Public Health Informatics

Mesquite 3

Keynote Speaker - Nirmal Keshava, AstraZeneca Mesquite 2

15:00 – 16:30 Session Fr3.1 Sensor Informatics-3

Mesquite 2

Panel-5: NSF/NIH Smart Connect Health Aspiring PI Workshop

Mesquite 3

Panel-6: Web-Based Public Health Informatics Mesquite 4

16:30 – 16:45 Coffee Break & Poster Session &Voting Paloverde A&B

16:45 – 18:15 Special Session-7: Progress in Health Informatics: Research and Applications

Mesquite 2

Special Session-8: Smart and Connected Health Mesquite 3

Panel-7: H4 Women in Biomedical and Health Informatics

Mesquite 4

18:15 – 19:30 CLOSED MEETING Best Paper/Poster Selection Committee (Sponsored by EMBS J-BHI)

Mesquite 5

19:30 – 21:00 Conference Banquet Casuarina Ballroom

xxiii

PROGRAM


SATURDAY, 27TH FEBRUARY 2016

08:00 – 08:45 Plenary Speaker - Russ Altman, Stanford University Acacia A-C

08:45 – 09:15 Leadership Forum: Vision for BHI in EMBS Best Paper/Poster Award

Acacia A-C

09:15 – 09:30 Coffee Break Mesquite Foyer

09:30 – 16:30 Workshop-1: Understanding How To Use Open Source Interoperability Standards for Medical Imaging, Devices, and Records (additional registration required, Breaks for lunch from 12:30-13:30)

Mesquite 2

09:30 – 12:30 Workshop 2: Health Informatics on FHIR: Opportunities in the New Age of Interoperability(additional registration required)

Mesquite 3

Workshop – 3: Big Data, SDN, and Healthcare (additional registration required)

Mesquite 4

09:30 – 11:00 Tutorial-1: Agile Modeling for Analysis and Design of Automated Clinical Decision Support in Electronic Health Records

Mesquite 5

11:00 – 12:30 Tutorial-2): Data Mining

Mesquite 5

12:30 – 13:30 Lunch Break (on own)

13:30 – 16:30 Workshop-4: Transforming 5P Pediatric Healthcare by Trans-Disciplinary Health Informatics

Mesquite 3

Workshop-5: Pathology Imaging Informatics

Mesquite 4

Tutorial-3: Colored Petri Nets Based Modeling and Simulation in Healthcare

Mesquite 5

16:30 – 16:45 Closing Remarks Acacia A-C

xxiv

Plenary & Keynote SPEAKERS


RUSS B. ALTMAN, MD, PHD

Chairman, Department of Bioengineering, Stanford University

Dr. Altman is a professor of bioengineering, genetics, & medicine (and of computer science by courtesy) and chairman of the bioengineering department at Stanford University. His primary research interests are in the application of computing technology to basic molecular biological problems of relevance to medicine. He is currently developing techniques for collaborative scientific computation over the internet, including novel

user interfaces to biological data, particularly for pharmacogenomics. Other work focuses on the analysis of functional microenvironments within macromolecules and the application of algorithms for determining the structure, dynamics and function of biological macromolecules. Dr. Altman holds an M.D. from Stanford Medical School, a Ph.D. in medical information sciences from Stanford, and an A.B. from Harvard College.

DOUGLAS B. FRIDSMA, MD, PHD, FACMI

President and Chief Executive Officer of American Medical Informatics Association, Arizona State University

Doug Fridsma, MD, PhD, FACP, FACMI, is the President and Chief Executive Officer of AMIA, a membership society representing 5000 professional and student informaticians and their interests and activities in academe, industry, government and nonprofit organizations.

Dr. Fridsma is an expert in informatics, interoperability, standards, and health IT (including meaningful use). His understanding of the science and application of informatics and experience as practitioner and policymaker give him a depth of knowledge well-suited to the critical challenge of transforming health and health care. Prior to joining AMIA, Dr. Fridsma was the Chief Science Officer for the Office of the National Coordinator for Health Information Technology, responsible for the portfolio of technical resources needed to support the meaningful use program and health information technology interoperability. While at ONC, he developed the standards and interoperability framework to accelerate the development of technical specifications for interoperability, and in collaboration with the NIH and other federal agencies, was instrumental in establishing the key priorities in the PCOR Trust fund. Prior to ONC, Dr. Fridsma held academic appointments at the University of Pittsburgh, Arizona State University, University of Arizona, and Mayo Clinic, and had a part-time clinical practice at the Mayo Clinic Scottsdale. He has served as a board member of HL7 and the Clinical Data Interchange Standards Consortium (CDISC) where he was instrumental in developing standards that bridge clinical care and clinical research.

xxv

Plenary & Keynote

SPEAKERS


KARL FRIEDL, PHD, COL (US ARMY, RET.)

University of California San Francisco School of Medicine

Karl Friedl, Ph.D., is a Fellow in the ORISE Knowledge Preservation Program and also an adjunct Professor in the Department of Neurology, University of California, San Francisco. He retired from thirty years of active duty service in the Army as a Colonel in 2013, where he had last served as Director of

the Telemedicine and Advanced Technology Research Center (TATRC) at the US Army Medical Research and Materiel Command. Dr Friedl received the M.A. degree in zoology from the University of California, Santa Barbara in 1979 and the Ph.D. degree in biology (integrative physiology) through the Institute of Environmental Stress in the University of California, Santa Barbara, in 1984. His research interest is focused on physiological modeling and monitoring technologies especially as applied to the limits of human performance. Dr. Friedl serves as Associate Editor of the IEEE Journal of Biomedical and Health Informatics. He is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE).

MICHAEL MCCOY

Physician Technology Services, Inc.

Michael McCoy, M.D. has diverse experience as a practicing clinician, a physician executive in the electronic health record vendor community, a national consultant, and as a large faith-based IDN’s first Chief Medical Information officer. In that role, he collaborated with information services

and the clinical transformation department in the effective implementation of computerized patient record systems, focusing on quality, safety, process improvement and ensuring that all clinicians are fully engaged in the entire process. He joined the federal government in a role as its first Chief Health Information Officer for The Office of the National Coordinator for Health Information Technology (ONC), departing that role January 31, 2016. Dr. McCoy was a practicing OB/GYN for more than 20 years, and was an early adopter of EMR systems. He served as The American College/Congress of Obstetricians and Gynecologists’ national health information technology strategist, participated in CCHIT, IHE, HITSP and other SDOs involved in healthcare information technology and interoperability. In addition to special interests in interoperability, he is passionate about consumer engagement, person-centered care, and privacy/security, and he serves on the Board of Directors of IHE International.

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NIRMAL KESHAVA, PHD

Senior Principal Informatics Scientist, Research & Development Information, AstraZeneca PLC

Dr. Keshava is an experienced big data scientist and leader that has developed innovative solutions for multi-disciplinary problems involving advanced sensor platforms and algorithms, rigorous performance

evaluation, and creative visualization. His contributions have spanned biomedical image/signal processing, neuroimaging, genomics, clinical informatics, biometrics, neuroscience, and multi-modal physiology. His goal is to generate insight and value by creatively exploiting data sets of all sizes and types and to work across boundaries to achieve project and institutional goals. Dr. Keshava’s background in signal processing is complemented by several years of in-depth technical and management experience and collaboration with many different academic, government, and commercial partners. He has served in a variety of leadership roles and enjoy defining visions and leading teams to achieve challenging goals.

EDWARD LIVINGSTON, MD

Deputy Editor, The Journal of The American Medical Association (JAMA)

Edward H. Livingston, M.D., F.A.C.S., A.G.A.F., has served as Deputy Editor for Clinical Content of JAMA, The Journal of the American Medical Association since July 1, 2012. Before that, he was a Contributing Editor at JAMA for 3 years.

Born and raised in Los Angeles, Dr. Livingston received his Medical Degree from UCLA. He completed a General Surgery Residency at UCLA and served as the Administrative Chief Resident for Surgery in 1992. After Residency, he remained on the faculty at UCLA eventually serving as Assistant Dean of the Medical School and Surgical Service Line Director for the VA Greater Los Angeles Health Care System. He also founded the UCLA bariatric surgery program. In 2003, he moved to Dallas to become the Professor and Chairman of GI and Endocrine Surgery at the University Of Texas Southwestern School Of Medicine. During this time period, Dr. Livingston headed the VA’s national effort in bariatric surgery quality improvement. He was appointed as a Professor of Biomedical Engineering in 2007 at the University of Texas Arlington. Dr. Livingston became Chairman of the Graduate Program in Biomedical Engineering at UTSW in 2010. Dr. Livingston has had peer review funding and has published in excess of 150 peer reviewed papers as well as numerous other scientific writings. He has also served on numerous local and national committees and is a past president of the Association of VA Surgeons. He continues to serve as a Professor of Surgery at UTSW.

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Plenary & Keynote

SPEAKERS


DAVID MENDELSON, MD

Professor of Radiology, Director of Radiologic Informatics and Chief of Clinical Informatics, Mount SinaiMedical Center, NY

Dr. Mendelson’s research interests include CT and MRI of the body, chest and cardiovascular imagine. He is involved in the development of solutions aimed at sharing medical images, managing incoming patient CD and also integrate and validate images into the hospital records.

ANDREAS SKOULOULDIS, PHD

European Commissions Principal Scientific Officer

Dr.Skoulouldis has over 25 years experience in the field of public health informatics and is currently with the European Commissions as principal scientific officer. His publications span the fields of sensor informatics, public health and environmental monitoring.

SHANKAR SUBRAMANIAM

UCSD

Shankar Subramaniam is a Distinguished Professor of Bioengineering, Computer Science and Engineering, Cellular and Molecular Medicine and Nano Engineering. He was recently the Chair of the Bioengineering Department at the University of California at San Diego (2008-13). He holds the inaugural Joan and Irwin Jacobs Endowed Chair in Bioengineering and Systems Biology. He was the Founding Director of the Bioinformatics

Graduate Program at the University of California at San Diego. He also has adjunct Professorships at the Salk Institute for Biological Studies and the San Diego Supercomputer Center. He was a Professor at the Center for Cardiovascular Bioinformatics and Modeling at Johns Hopkins University and was a Guest Professor at the Center for Molecular Biology and Neuroscience at the University of Oslo in Norway. Prior to moving to UC San Diego, Dr. Subramaniam was a Professor of Biophysics, Biochemistry, Molecular and Integrative Physiology, Chemical Engineering and Electrical and Computer Engineering at the University of Illinois at Urbana-Champaign (UIUC). He was the Director of the Bioinformatics and Computational Biology Program at the National Center for Supercomputing Applications and the Co-Director of the W.M. Keck Center for Comparative and Functional Genomics at UIUC. He is a fellow of the American Association for the Advancement of Science and the American Institute for Medical and Biological Engineering (AIMBE) and is a recipient of Smithsonian Foundation and Association of Laboratory Automation Awards. In 2013 he was elected as a Fellow of AAAS. In 2002 he received the Genome Technology All Star Award. In 2008 he was awarded the Faculty Excellence in Research Award at the University of California at San Diego. In 2011 he was appointed as a Distinguished Scientist at the San Diego Supercomputer Center. In 2014 he was appointed as a Distinguished Professor. His research spans several areas of bioinformatics and systems biology.

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SHENG ZHONG, PHD

Associate Professor of Bioengineering, UCSD (Bioinformatics)

Sheng double majored in Mathematics and Economics in Beijing University. He obtained a Ph.D. in Biostatistics and fulfilled a Ph.D. Minor of Molecular Biology at Harvard University. He worked at Stanford University and University of Illinois Urbana-Champaign before moving to UCSD. He received NSF CAREER Award, Alfred Sloan Fellowship, and NIH Pioneer Award. He serves as an Associate Editor for PLoS Computational Biology, and the contact PI for NIH 4D Nucleome organizational hub.

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INVITED PANEL

SPEAKERS


MARK CAPRARA, PH.D.

Center for Scientific Review, the National Institutes of Health

Dr. Caprara is the Scientific Review Officer for the Biodata Management and Analysis Study Section. He oversees the review of applications that focus on computational methods for the acquisition, management, querying, sharing and analysis of biological and clinical data. Prior to joining NIH he was an

assistant professor at Case Western Reserve University Medical School conducting research on RNA processing and mobile genetic elements.

VALERIE FLORANCE, PH.D.

Director, NLM Extramural Programs, Heads NLM’s Extramural Programs Division, which is responsible for the Library’s grant programs. Coordinator for NLM informatics training programs.

Valerie Florance, Ph.D., is an Associate Director of the National Library of Medicine, NIH. There, she directs NLM’s Extramural Programs Division, with

overall responsibility for research, training and resource grant programs in biomedical informatics and health information sciences. She serves as program director for NLM’s highly-regarded university-based training programs in biomedical informatics. Dr. Florance is a member of the Executive Committee for the NIH Big Data to Knowledge (BD2K) initiative. Before coming to NLM in February 2001, she spent 3 years leading a visioning project undertaken at the Association of American Medical Colleges (AAMC) to help the association’s members understand the power of computers and networks for managing health information. Before that, she held faculty and administrative positions at three U.S. academic medical centers. She has graduate degrees in medical anthropology and biomedical information sciences, and was elected to the American College of Medical Informatics in 2005.

DAN GALLAHAN, PH.D.

Deputy Division Director, Division of Cancer Biology, NCI

Dr. Gallahan helps lead the Division in its mission of supporting and facilitating basic cancer biology research. His primary focus at NCI is the application of integrated approaches, tools, and data sets to understanding cancer. He established and still oversees the Division’s efforts in cancer systems biology,

the latest of which is the Cancer Systems Biology Consortium (CSBC). As Deputy Director, he also assists in planning and implementing the NCI’s overall efforts in genomics, proteomics, structural biology, and nanotechnology, and is a liaison with other government and commercial entities in the areas of technology and systems biology. Dr. Gallahan is a molecular and cancer biologist with broad expertise in the fields of systems biology, breast cancer, technology development, and science policy.

xxx

INVITED PANEL SPEAKERS


WENDY NILSEN, PH.D.

Program Director, National Science Foundation

Wendy Nilsen, Ph.D. is a Program Director for the Smart and Connected Health Program in the Directorate for Computer & Information Science & Engineering at the National Science Foundation. Her work focuses on the

intersection of technology and health. This includes a wide range of methods for data collection, data analytics and turning data to knowledge. Her interests span the areas of sensing, analytics, cyber-physical systems, information systems, big data and robotics, as they relate to health. More specifically, her efforts include: serving as cochair of the Health Information Technology Research and Development community of practice of the Networking and Information Technology Research and Development Program; the lead for the NSF/NIH Smart and Connected Health announcement; convening workshops to address methodology in mobile technology research; serving on numerous federal technology initiatives; and, leading training institutes. Previously, Wendy was at the NIH Office of Behavioral and Social Sciences Research (OBSSR).

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1

Program in Chronological Order

* – Corresponding Author

Wednesday, 24 February 2016

WeA1T1: 13:30-14:15 Mesquite 2 Wed1.1 Theoretical Informatics-1 (Regular Session)

13:30-13:45 WeA1T1.1 Applying Attribute based Access Control for Privacy Preserving Health Data Disclosure

Ray, Indrakshi* (Colorado State University); Ong, Toan C. (Anschutz Medical Center, University of Colorado, Denver); Ray, Indrajit (Colorado State University); Kahn, Michael G. (Anschutz Medical Center, University of Colorado, Denver)

13:45-14:00 WeA1T1.2 Data Security and Privacy Management in Healthcare Applications and Clinical Data Warehouse Environment

Puppala, Mamta* (Houston Methodist Research Institute, Weill Cornell Medical College); He, Tiancheng (Methodist Hospital Research Institute, Weill Cornell Medical College); Yu, Xiaohui (Houston Methodist Research Institute, Weill Cornell Medical College); Chen, Shenyi (Houston Methodist Research Institute, Weill Cornell Medical College); Ogunti, Richard (Houston Methodist Research Institute, Weill Cornell Medical College); Wong, Stephen T.C. (The Methodist Hospital Research Institute, Weill Cornell Medical College)

14:00-14:15 WeA1T1.3 Watermarking of Radiographic Images based on Quantum Noise Modulation

Karasad, Mohamed (Telecom Bretagne); Bouslimi, Dalel* (Telecom Bretagne); Cozic, Michel (MEDECOM); Coatrieux, Gouenou (Institut Telecom - Telecom Bretagne - Inserm)

WeA1T3: 13:30-15:00 Mesquite 4 Too Much Data Too Little Time: Pressures, Practice and Possibilities for Use of Big-Data Strategies and Analytics in Healthcare (Special Session) 13iww

13:30-13:45 WeA1T3.1 Application of Big-Data in Healthcare Analytics – Prospects and Challenges

Rahman, Fuad* (Apurba Technologies Inc.); Slepian, Marvin J. (University of Arizona)

13:45-14:00 WeA1T3.2 Opportunities and Challenges in Defining a Big-Data Effort in Healthcare

Hossainy, Syed* (Abbott)

14:00-14:15 WeA1T3.3 Big Data – Still in the Workshop – What is Everyone Working On?

Sarrel, Matt* (Sarrel Group)

14:15-14:30 WeA2T3.4 Organizing the Universe of Mobile Health Data and Making It Actionable

Kharebov, Akhsar* (Validic)

WeA2T2: 14:15-15:00 Mesquite 3 Wed2.2 Imaging Informatics-2 (Regular Session)

14:15-14:30 WeA2T2.1 Multi-Modal Learning-Based Pre-Operative Targeting in Deep Brain Stimulation Procedures

Liu, Yuan* (Vanderbilt University); Dawant, Benoit (Vanderbilt University)

14:30-14:45 WeA2T2.2 Heterogeneity of Colorectal Cancer Cell Positions as a Cell Viability Biometric

Saribudak, Aydin* (CCNY); Kucharavy, Herman (City College of New York); Hubbard, Karen (City College of New York); Uyar, M. Umit (City College of New York)

14:45-15:00 WeA2T2.3 An Automated Approach to Detect Human Ovarian Tissues using Type P63 Counter Stained Histopathology Digitized Color Images

Sazzad, T M Shahriar* (Edith Cowan University); Armstrong, L. J. (Edith Cowan University); Tripathy, A. K. (Don Bosco Institute of Technology)

WeBT1: 15:00-16:30 Mesquite 2 Wed2.1 Theoretical Informatics-2 (Wearable Technologies) (Regular Session)

15:00-15:15 WeBT1.1 Modified Logistic Regression Algorithm for Accurate Determination of Heart Beats from Noisy Passive RFID Tag Data

Vora, Shrenik* (Drexel Univ.); Kurzweg, Timothy (Drexel Univ.)

15:15-15:30 WeBT1.2 On the Remote Detection of COPD-Related Worrisome Events

Merone, Mario* (Università Campus Biomedico di Roma); Onofri, Leonardo (Università Campus Bio-Medico di Roma); Pedone, Claudio (Università Campus Biomedico di Roma); Bussu, Angela Maria (ASL (Azienda Ospedaliera Locale) n. 4 Lanuesi); Rubiu, Barbara Francesca Maria (ASL (Azienda Ospedaliera Locale) n. 4 Lanuesi); Capasso, Giuseppe (Laboratori di Informatica Applicata); Salaris, Silvano (Laboratori Informatica Applicata); Iannello, Giulio (Università Campus Bio-Medico di Roma); Antonelli Incalzi, Raffaele (Università Campus Bio-Medico di Roma); Soda, Paolo (Università CAMPUS Bio-Medico)

15:30-15:45 WeBT1.3 Quantitative and Qualitative Comparison of Periodic Sensor Data

Jain, Akshay* (University of Missouri-Columbia); Keller, James M (University of Missouri); Bezdek, James (University of Missouri)

15:45-16:00 WeBT1.5 Wrist Pulse Measurement and Analysis using Eulerian Video Magnification

He, Xiaochuan* (Carleton University); Goubran, Rafik A. (Carleton University); Liu, Peter X. (Carleton University)

16:00-16:15 WeBT1.6 A Frequency Domain Algorithm to Identify Recurrent Sedentary Behaviors from Activity Time-Series Data

He, Qian* (Worcester Polytechnic Institute); Agu, Emmanuel (Worcester Polytechnic Institute)

WeBT2: 15:00-16:30 Mesquite 3 Wed1.2 Imaging Informatics-1 (Regular Session)

15:00-15:15 WeBT2.1 A Framework for Mapping Scalable Human Brain Anatomical Networks via Diffusion MRI

Liao, Ruizhi (Massachusetts Institute of Technology); Dou, Weibei* (Tsinghua University); Zhang, Mingyu (Tian Tan Hospital, Capital Medical University, Beijing, China); Chen, Hongyan (Capital Medical University–Tian Tan Hospital); Li, Shaowu (Beijing Neurosurgical Institute, Beijing, China)

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15:15-15:30 WeBT2.2 A Robust and Adaptive Decision-Making Algorithm for Detecting Brain Networks using Functional MRI within the Spatial and Frequency Domain

Sarraf, Saman* (Rotman Research Institute at Baycrest); Saverino, Cristina (Rotman Research Institute at Baycrest); Golestani, Ali Mohammad (Rotman Research Institute at Baycrest)

15:30-15:45 WeBT2.3 Hierarchical Subdivision and Effect of ICA Model Dimensionality on the Interoceptive Task-Derived Brain Networks

Jarrahi, Behnaz* (University of California, Los Angeles); Mantini, Dante (ETH)

15:45-16:00 WeBT2.4 Measurement and Comparison of Thermal and In-Bed Pressure Data towards the Prevention of Pressure Ulcers

Bennett, Stephanie Louise* (Carleton University); Goubran, Rafik A. (Carleton University)

16:00-16:15 WeBT2.5 Blind Image Deconvolution based on Robust Stable Edge Prediction

Li, Wei (Inha University); Cui, Xuenan (Inha University); Nguyen, Van Huan (Inha University); Do, Trung Dung (Inha University); Park, Iju (Inha University); Kim, Hakil* (Inha University)

16:15-16:30 WeBT2.6 How Divided is a Cell? Eigenphase Nuclei for Classification of Mitotic Phase in Cancer Histology Images

Awan, Ruqayya (Qatar University); Aloraidi, Nada (Qatar University); Qidwai, Uvais (Qatar University); Rajpoot, Nasir* (Qatar University & University of Warwick)

WePM_Poster_T1: 16:30-16:45 Paloverde A&B Bioinformatics Poster Session (Poster Session)

16:30-16:45 WePM_Poster_T1.1 Evaluating the Impact of Sequencing Error Correction for RNA-Seq Data with ERCC RNA Spike-In Controls

Tong, Li* (Georgia Institute of Technology); Yang, Cheng (Peking University); Wu, Po-Yen (Georgia Institute of Technology); Wang, May D. (Georgia Tech and Emory University)

16:30-16:45 WePM_Poster_T1.2 The Selection of Quantification Pipelines for Illumina RNA-Seq Data using a Subsampling Approach

Wu, Po-Yen* (Georgia Institute of Technology); Wang, May D. (Georgia Tech and Emory University)

16:30-16:45 WePM_Poster_T1.5 Quantification of Cell Apoptosis for In-Vitro Colorectal Cancer Cell Cultures based on Morphological Features

Saribudak, Aydin* (CCNY); Kucharavy, Herman (City College of New York); Hubbard, Karen (City College of New York); Uyar, M. Umit (City College of New York)

WePM_Poster_T2: 16:30-16:45 Paloverde A&B Health Informatics Poster Session (Poster Session)

16:30-16:45 WePM_Poster_T2.1 PEPCOR – A Risk Prediction Model for Pediatric Intensive Care Units Utilizing Ventilator Days and Length of Stay

Pethiyagoda, Theruni* (Georgia Institute of Technology); Cheng, Chihwen (Georgia Institute of Technology); Wang, May D. (Georgia Tech and Emory University); Chanani, Nikhil (Emory University School of Medicine)

16:30-16:45 WePM_Poster_T2.2 Segmentation of Sacral Curve on Dynamic MRI for Diagnosis of Pelvic Organ

Onal, Sinan* (Southern Illinois Univ., Edwardsville); Chen, Xin (Southern Illinois Univ., Edwardsville); Lai-Yuen, Susana (Univ. of South Florida); Hart, Stuart (Univ. of South Florida)

16:30-16:45 WePM_Poster_T2.5 Adaptive Network Selection Mechanism for Telecardiology System in Developing Countries

Yew, Hoe Tung (Univ. Malaysia Sabah); Supriyanto, Eko* (Univ. Teknologi Malaysia); Satria, Muhammad Haikal (Univ. Teknologi Malaysia); Hau, Yuan Wen (Univ. Teknologi Malaysia)

16:30-16:45 WePM_Poster_T2.6 A Real-Time Detection and Warning of Cardiovascular Disease LAHB for a Wearable Wireless ECG Device

Arunan, Anjali (Amrita Vishwa Vidyapeetham); Pathinarupothi, Rahul Krishnan* (Amrita Vishwa Vidyapeetham); Ramesh, Maneesha Vinodini (Amrita Vishwa Vidyapeetham)

16:30-16:45 WePM_Poster_T2.7 Design of Automatic Insulin Injection System with Continuous Glucose Monitoring (CGM) Signals

Jung, Changyong (Andrew)* (Framingham State University); Lee, Suk Jin (Texas A & M University - Texarkana)

16:30-16:45 WePM_Poster_T2.8 Semantic-Based Approach for Predicting Venous Thromboembo-lism using Kohonen Self Organized Map Neural Network

Sabra, Susan* (Oakland University); Mahmood, Khalid (Oakland University); Alobaidi, Mazen (Oakland University)

16:30-16:45 WePM_Poster_T2.9 Voice-Activity Home Care System

Chen, Oscal Tzyh-Chiang* (National Chung Cheng Univ.); Tsai, Yi-Heng (National Chung Cheng Univ.); Su, Che-Wei (National Chung Cheng Univ.); Kuo, Po-Chen (National Chung Cheng Univ.); Lai, Wei Chih (National Chung Cheng Univ.)

16:30-16:45 WePM_Poster_T2.10 Using CART to Minimize Data Entry Required for a Decision Aid App Assisting with Lifestyle Choices

Finkelstein, Joseph* (Johns Hopkins University School of Medicine); Jeong, In Cheol (Johns Hopkins University); Kukafka, Rita (Columbia University)

16:30-16:45 WePM_Poster_T2.11 Detection of Blood Loss in Trauma Patients using Time-Frequency Analysis of Photoplethysmographic Signal

Reljin, Natasa* (University of Connecticut); Zimmer, Gary (UMass Medical School); Malyuta, Yelena (University of Massachusetts Medical School, Department of Emerge); Mendelson, Yitzhak (Worcester Polytechnic Institute); Darling, Chad (UMass Medical School); Chon, Ki (University of Connecticut)

16:30-16:45 WePM_Poster_T2.12 Development and User Feedback of Home Technology for Preventing Falls in Older Adults

Immonen, Milla Sinikka* (VTT Technical Research Centre of Finland); Similä, Heidi (VTT Technical Research Centre of Finland Ltd); Arabiurrutia Altube, Elixabete (Hospital La Fuenfría); Cano Mañas, Maria Jose (Hospital La Fuenfría); Blanco Laguía, Jesús (Hospital La Fuenfría); Palmer García, Cristina (Hospital La Fuenfría); García-Gordillo, Carlos (Freelance Management Consultant)

16:30-16:45 WePM_Poster_T2.13 Identifying Peripheral Arterial Disease Cases using Natural Language Processing of Clinical Notes

Afzal, N.* (Mayo Clinic Rochester MN); Liu, H. (Mayo Clinic)

16:30-16:45 WePM_Poster_T2.14 Analyzing Dynamic Components of Social Scene Parsing Strategy in Autism Spectrum Disorder

Song, Chen* (Univ. at Buffalo, The State University of New York); Wang, Aosen (University at Buffalo); Michelle, Hartley-McAndrew (Children's Guide Foundation Autism Spectrum Disorder Center); Kathy, Doody (University at Buffalo, The State University of New York); Jana, Mertz (Children's Guide Foundation Autism Spectrum Disorder Center); Lin, Feng (University at Buffalo); Xu, Wenyao (SUNT at Buffalo)

3

16:30-16:45 WePM_Poster_T2.15 Assessing the Comorbidity Gap between Clinical Studies and Prevalence in Elderly Patient Populations

He, Zhe* (Florida State Univ.); Charness, N. (Florida State Univ.); Bian, Jiang (Univ. of Florida); Hogan, William (Univ. of Florida)

16:30-16:45 WePM_Poster_T2.16 Analyzing Drug Sensitivity Prediction based on Dose Response Curve Characteristics

Rahman, Raziur (Texas Tech University); Pal, Ranadip* (Texas Tech University)

16:30-16:45 WePM_Poster_T2.17 Bio-Inspired Filter Banks for SSVEP-Based Brain-Computer Interfaces

Demir, Ali Fatih* (Univ. of South Florida); Arslan, Huseyin (Univ. of South Florida); Uysal, Ismail (Univ. of South Florida)

16:30-16:45 WePM_Poster_T2.18 Towards Clinically Relevant Automatic Assessment of Upper-Limb Motor Function Impairment

Lee, Seung-Hee (Daegu Gyeongbuk Institute of Science & Technology); Kim, Jonghyun* (Daegu Gyeongbuk Institute of Science and Technology (DGIST)); Song, Minsu (DGIST, 333, Techno jungang-daero, Hyeonpung-myeon, Dalseong-gun)

16:30-16:45 WePM_Poster_T2.19 Android based Digital Fetoscope

Muga, Angeline Awiti* (Makerere University Kampala); Shifferaw, Besufekad (Makerere University Kampala); Baguma, Maximus Byamukama (Makerere University Kampala); Kizito, Ronald (Makerere University Kampala); Mwikirize, Cosmas (Rutgers, the State University of New Jersey)

16:30-16:45 WePM_Poster_T2.20 Implementation and User Testing of a System for Visualizing Continuous Health Data and Events

Al-Musawi, Mohammed* (Tampere University of Technology); Ledesma, Andres (Tampere University of Technology); Nieminen, Hannu (Tampere University of Technology); Korhonen, Ilkka (Tampere University of Technology)

WePM_Poster_T3: 16:30-16:45 Paloverde A&B Imaging Informatics Poster Session (Poster Session)

16:30-16:45 WePM_Poster_T3.1 Automated Prediction for Esophageal Optical Endomicroscopic Images

Kothari, Sonal (Georgia Institute of Technology); Wu, Hang (Georgia Institute of Technology); Tong, Li (Georgia Institute of Technology); Woods, Kevin (Emory University School of Medicine); Wang, May D.* (Georgia Tech and Emory University)

16:30-16:45 WePM_Poster_T3.2 C-Arm Technique with Distance Driven for Nephrolithiasis and Kidney Stones Detection: Preliminary Study

Malalla, Nuhad* (Southern Illinois Univ. of Carbondale); Pengfei, Sun (Southern Illinois Univ. Carbondale); Ying, Chen (Southern Illinois Univ. of Carbondale); Michael, Lipkin (Duke Univ. Medical Center); Glenn, Preminger, (Duke Univ. Medical Center); Qin, Jun (Southern Illinois Univ. Carbondale)

16:30-16:45 WePM_Poster_T3.3 Superpixel-Based Automatic Segmentation of Villi in Confocal Endomicroscopy

Boschetto, Davide* (IMT Institute for Advanced Studies Lucca); Mirzaei, Hadis (Univ. of New South Wales); Leong, Rupert (Univ. of New South Wales); Grisan, Enrico (Univ. of Padova)

16:30-16:45 WePM_Poster_T3.4 Grading of Mammalian Cumulus Oocyte Complexes using Machine Learning for in Vitro Embryo Culture

Mandal, Subhamoy (TU Munich and Helmholtz Zentrum Munich); P Sudarshan, Viswanath* (TU Munich)

16:30-16:45 WePM_Poster_T3.5 Quantitative Measurement of Vasculature in Coronary Angiogram Videos

Soroushmehr, S.M.Reza* (University of Michigan, Ann Arbor); Bafna, Abhishek (University of Michigan, Ann Arbor); Sinha, Shashank (University of Michigan); Nallamothu, Brahmajee (University of Michigan); Ward, Kevin (Virginia Commonwealth University); Najarian, Kayvan (University of Michigan - Ann Arbor)

16:30-16:45 WePM_Poster_T3.6 A Fusion Method for Pulmonary Nodule Segmentation in Chest CT Image Sets

Tunali, Ilke (Namik Kemal Univ.); Guvenis, Albert* (Bogazici Univ.)

16:30-16:45 WePM_Poster_T3.7 A Semi-Automated Technique for Internal Jugular Vein Segmentation in Ultrasound Images using Active Contours

Karami, Ebrahim (Memorial University); Shehata, Mohamed (Memorial University of Newfoundland); McGuire, Peter (Centre for Cold Oceans Resource Engineering); Smith, Andrew* (Memorial University of N

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