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2018 INTERNATIONAL SYMPOSIUM ON THE
FRONTIERS AND PRACTICE
OF INNOVATIVE DRUG DISCOVERY
THE 8TH INTERNATIONAL SYMPOSIUM ON
DNA-ENCODED CHEMICAL LIBRARIES
. ………
Chengdu Marriot Financial Centre
Chengdu, China
October 17-19, 2018
www.dnaencodedlibrary.com
www.innovativedrugdiscovery.com
On behalf of the Organising Committees for 2018 International Symposium on the Frontiers and Practice of Innovative
Drug Discovery and the 8th International Symposium on DNA-Encoded Chemical Libraries, we are delighted to invite
you to join in this exciting events which will be held on Oct. 17-19th, 2018 at the Marriot Hotel Financial Center in Chengdu,
China.
With a theme of “INNOVATION, PRAGMATISM, COLLABORATION”, industry experts and academic investigators in this
increasingly important area will assemble to present and discuss the most recent developments and applications of this
technology to early-stage small molecule drug discovery. Through a series of innovative R&D case studies, workshops,
One-on-one Partnering Meeting, Road Show, Exhibition and Poster Presentation we will facilitate an international
event with the capacity for thousands of attendees to participate in discussions and contribute to possible business
collaborations across the industrial and academic spectrum.
Symposium Introduction
Date: Oct. 17-19th, 2018
Location: Marriot Hotel Financial Center, Chengdu, China
Language: English
Symposium Topics
2018 International Symposium on the Frontiers and Practice of Innovative Drug Discovery
Session 1: Analysis of Industrial Trends and Policies, Frontiers in Innovative Drug Discovery & Development
Session 2: Case Studies of the Latest Innovative Drug Discovery & Development
Session 3: New Approaches to Drug Discovery & Development: AI Application, Big Data, Block Chain, etc.
8th International Symposium on DNA-Encoded Chemical Libraries
Session 1: Development of On-DNA Chemical Synthesis
Session 2: New Technologies for DNA-encoded Library Selection and Hit Identification
Session 3: Case Studies: Clinical Candidates from DNA-Encoded Libraries
WARM WELCOME
CO-ORGANIZER
SUPPORTERS
ORGANIZER
HOST
MEDIA
2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE
OF INNOVATIVE DRUG DISCOVERY
THE 8TH INTERNATIONAL SYMPOSIUM ON
DNA-ENCODED CHEMICAL LIBRARIES
COMMITTEE MEMBERS
Dr. Mingde Xia
Senior Director
Innovation center, Asia pacific,
Johnson & Johnson
Dr. Min Wu
Executive Director
Asia Pacific Innovation AP
Innovation Hub, BD&L. MSD
R&D (China) Co., Ltd.
Dr. Jin Li
Founder, Chairman & CEO
HitGen Ltd.
Dr. Yuan-Hua Ding
Executive Director and Head of
External Science & Innovation
(ES&I), Asia-Pacific, Pfizer
Dr. Bo Chen
Founder & Chairman
ConMed Biosciences Inc.
Dr. Xianping Lu
CEO & CSO
Chipscreen Biosciences
Dr. Changyu Wang
Founder & CEO
Huamian Biotechnology
COMMITTEE MEMBERS
Dr. Alex Shaginian
Senior Director of Business
Development and Chemical
Sciences, HitGen Ltd.
Dr. Barry Morgan
Chief Scientific Officer,
HitGen Ltd.
Prof. Dario Neri
Department of Chemistry and Applied
Biosciences, Swiss Federal Institute
of Technology (ETH Zürich) & Co-
founder, Philogen
Dr. Sylvie K. Sakata
Head of External Research Solutions,
Global Research & Development,
Pfizer
Dr. Jinqiao Wan
Vice President
Discovery Chemistry Unit,
HitGen Ltd.
Dr. Robert Goodknow
Vice President
Innovation Chemistry, Pharmaron
Dr. Zhicai Shi
Director of Chemistry
Merck Sharp & Dohme
Dr. Bing Xia
Investigator, NCE ELTs Boston
RD Platform Technology & Science,
GSK
GlaxoSmithKline
b
CONFIRMED SPEAKERS
Dr. John R Jacobsen
Senior Vice President, Chemistry,
DiCE Molecules SV, Inc
Dr. Kenneth E Lind
Manager-Scientific
Computing, R&D Platform
Technology & Science, GSK
Dr. Lipeng Lai
Co-founder and General
Manager of Xtalpi Inc.
Dr. Pei-Pei Kung
Associate Research Fellow, Pfizer
Dr. Yuan-Hua Ding
Executive Director and Head of
External Science & Innovation
(ES&I), Asia-Pacific, Pfizer
Dr. Lianshan Zhang
Senior Vice President and Global
R&D President of Jiangsu Hengrui
Medicine Co.,Ltd.
Dr. Lee Babiss
President, SYNBLic
Dr. Joseph Duffy
Head of External Discovery Chemistry,
Merck Research Lab, Merck & Co., Inc
Dr. Matthew Tremblay
Vice President, Business Development,
The Scripps Research Institute
Prof. Xiaoyu Li
University of Hongkong
Dr. Alexander L. Satz
Senior Principal Scientist
Roche
Dr. Anthony D Keefe
Vice President
Discovery Technology, X-Chem
Dr. Barry Morgan
Chief Scientific Officer
HitGen Ltd.
Dr. Bernd Nosse
Global Head BD&L Technologies,
Boehringer Ingelheim Pharma
GmbH & Co. KG
Dr. Bing Xia
Investigator, NCE ELTs Boston
RD Platform Technology &
Science, GSK
Prof. Dario Neri
Department of Chemistry and Applied
Biosciences, Swiss Federal Institute of
Technology & Co-founder, Philogen
Dr. Jie Wang
Post doctor, Department of
Chemistry, TSRI
Dr. Nick Terrett
Scientific Associate Vice
President of European Chemistry
Lead, MSD International GmbH
Dr. Petr Vachal
Associate Vice President of
Discovery Chemistry, Merck &
Co., Inc
Dr. Robert Goodknow
Vice President
Innovation Chemistry, Pharmaron
Dr. Wei Chen
CEO, NetVation DL
Medicine
Dr. Xiaojie Lu
Principal Investigator
Shanghai Institute of Materia Medica
Dr. Zhiqiang An
UT’s Institute of Molecular
Medicine in Houston
Dr. Min Wu
Executive Director, Asia Pacific
Innovation AP Innovation Hub,
BD&L. MSD R&D (China) Co.,
Ltd. Dr. Mingde Xia
Senior Director
Innovation center, Asia pacific,
Johnson & Johnson
Dr. Zhong-Yin Zhang
Director of Purdue Institute for
Drug Discovery
Prof. Mark P. Waller
Shanghai University
Dr. David Isreal
Vice President
Lead Discovery Sciences,
HitGen Ltd.
Dr. Dominik K. Kölmel
Senior Scientist, Worldwide
Research and Development,
Pfizer
Prof. Jianfeng Pei
Associate Professor
Peking University
Ms. Lily Zhang
Partner
CDH Investment
Ms. Lynn Yang
Managing Director
Sequoia Capital
2018 INTERNATIONAL SYMPOSIUM ON THE FRONTIERS AND PRACTICE
OF INNOVATIVE DRUG DISCOVERY
October 18, 2018
9 talks + 1 panel discussion
08:00-09:00 On-site Registration
08:30-18:00 Poster Presentation
08:30-18:00 Exhibition Open
13:00-18:00 One-on-One Partnering Meeting
Session1: Analysis of Industrial Trends and Policies, Frontiers in Innovative Drug Discovery & Development
09:00-9:20 OPENING CEREMONY
Welcome speech & Introduction of speakers
09:20-09:45 Government speech of Chengdu Tianfu International Bio-town
Project Signing Ceremony: Scripps Project
09:45-10:15 TOPIC: TBD
Dr. Dan Wang, Head of Johnson & Johnson Innovation Asia-Pacific
10:15-10:45 TOPIC: TBD
Dr. Will Somers, Vice President and Head of BioMedicine Design, Pfizer
10:45-11:00 Conference Photo & Tea Break
11:00-11:30 Talk
11:30-12:00 Talk
12:00-13:00 Lunch & Exhibition & Poster Presentation
13:00-13:30 TOPIC: TBD
HitGen Ltd.
13:30-14:00 TOPIC: Synergies Between Innovation and Drug Development at Scripps
Dr. Matthew Tremblay, Vice President of Business Development, The Scripps Research Institute
& Chief Operating Officer of California Institute for Biomedical Research
Session 2: Case Studies of the Latest Innovative Drug Discovery & Development
14:00-14:30 TOPIC: High-Throughput Experimentation for the Optimized Synthesis of TROX-1, a
Cav2.2 Blocker for the Treatment of Chronic Pain
Dr. Joseph Duffy, Head of External Discovery Chemistry, Merck Research Lab, Merck & Co., Inc
14:30-15:00 TOPIC: The Evolving Saga of Research & Development
Dr. Lee Babiss, President of SYNBLic
15:00-15:30
TOPIC: TBD
Dr. Lianshan Zhang, Senior Vice President and Global R&D President of Jiangsu Hengrui
Medicine Co., Ltd.
15:30-15:45 Tea Break & Exhibition & Poster Presentation
Panel Discussion: Cross-border Collaboration and Licensing
in New Drug Discovery & Development
October 17, 2018
Opening Reception
15:00-21:00 On-site Registration
17:30-20:00 Dinner
AGENDA
15:45-16:30 Chairperson :
Panel Speakers:
Dr. Yuan-Hua Ding, Executive Director and Head of External Science & Innovation (ES&I), Asia-
Pacific, Pfizer
Dr. Mingde Xia, Senior Director, Innovation center, Asia pacific, Johnson & Johnson
Dr. Min Wu, Executive Director, Asia Pacific Innovation AP Innovation Hub, BD&L. MSD R&D
(China) Co., Ltd.
Dr. Bernd Nosse, Global Head BD&L Technologies, Boehringer Ingelheim Pharma GmbH & Co.
KG
16:30-17:45 SAPA Roadshow
17:45-18:00 Poster Presentation
18:00-20:00 Dinner– PLACE （TBD）
October 19, 2018
9 talks + 1 panel discussion
08:30-18:00 Poster Presentation
08:30-18:00 Exhibition
08:30-18:00 One-on-One Partnering Meeting
Session 2: Case Studies of the Latest Innovative Drug Discovery & Development (3 talks)
09:00-09:30 TOPIC: Antibody Drug Discovery: Challenges and Opportunities
Prof. Zhiqiang An, UT’s Institute of Molecular Medicine in Houston
09:30-10:00 TOPIC: Drugging the Undruggable: Targeting Protein Tyrosine Phosphatases for Novel
Therapeutics
Prof. Zhong-Yin Zhang, Director, Purdue Institute for Drug Discovery
10:00-10:30 Talk
10:30-10:45 Tea Break & Exhibition & Poster Presentation
Session 3: New Approaches to Drug Discovery & Development: AI Application, Big Data, Block Chain, etc.
10:45-11:15 TOPIC: Drug Discovery Enabled
Dr. Petr Vachal, Associate Vice President, Discovery Chemistry, Merck & Co., Inc.
11:15-11:45 TOPIC: TBD
Dr. Lipeng Lai, Co-founder and General Manager of Xtalpi Inc.
11:45-12:15 TOPIC: Prediction of Druggable Proteins Using a Word2vec Algorithm
Prof. Jianfeng Pei, Associate Professor, Peking University
12:15-13:15 Lunch & Exhibition & Poster Presentation
13:15-14:45 TOPIC: TBD
Prof. Mark P. Waller, Shanghai University
14:45-15:15 TOPIC: TBD
Dr. Zhiyong Xie, Director of Digital Medicine, Pfizer
15:15-15:45 Talk
Panel Discussion: Biomedical Investment Environment and Trends
15:45-16:30 Chairperson:
Panel Speakers:
Ms. Lynn Yang, Managing Director, Sequoia Capital
Ms. Lily Zhang, Partner, CDH Investment
16:30-17:45 Road Show
17:45-18:00 Closing Remarks
18:00-20:00 Closing Dinner – PLACE (TBD)
THE 8TH INTERNATIONAL SYMPOSIUM ON DNA-ENCODED CHEMICAL LIBRARIES
October 19, 2018
TIME TOPIC & SPEAKER MODERATOR
08:30-09:00 On-site Registration
09:00-09:10
Introduction and Welcome
Jin Li, PhD, Founder and Chairman & CEO of HitGen
Session 1: Development of On-DNA Chemical Synthesis MODERATOR
09:10-09:40 Talk Barry Morgan, PhD, Chief Scientific Officer of HitGen
09:40-10:10
TOPIC: Employing Photoredox Catalysis for the Synthesis of DNA-encoded Libraries Dominik K. Köelmel, PhD, Senior Scientist, Worldwide Research and Development, Pfizer
10:10-10:40
TOPIC: Forging Csp3-Csp3 and Csp3-Csp2 Bonds in DEL-Format Jie Wang, PhD, Post doctor, Department of Chemistry, The Scripps Research Institute
10:40-11:00 Tea Break
11:00-11:30
TOPIC: Encoded Self-Assembling Chemical (ESAC) Libraries Dario Neri, Professor, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology
11:30-12:00 Talk
12:00-13:00 Lunch
Session 2: New Technologies for DNA-encoded Library Selection and Hit Identification MODERATOR
13:00-13:30 TOPIC: TBD David Israel, PhD, Vice President of Lead Discovery Sciences, HitGen
Dario Neri, Professor, ETH Zürich
13:30-14:00 TOPIC: The Encoded Library Technology Data Analysis Platform at GSK Kenneth E Lind, PhD, Manager – Scientific Computing, R&D Platform Technology & Science, GSK
14:00-14:30 TOPIC: DNA-Programmed Chemistry: Application to Lead Expansion of a Peptide Macrocycle John R Jacobsen, PhD, Senior Vice President, Chemistry, DiCE Molecules SV, Inc
14:30-15:00 Talk
15:00-15:20 Tea Break
Session 3: Case Studies: Clinical Candidates from DNA-Encoded Libraries MODERATOR
15:20-15:50 TOPIC: Use of DNA encoded libraries at Roche Alexander L. Satz, PhD, Senior Principal Scientist, Roche
Nick Terrett, PhD, VP of European Chemistry Lead, MSD International GmbH
15:50-16:20 TOPIC: Characterization of specific Naa50 inhibitors identified using a DNA encoded library: a lead-finding case study for a challenging target Pei-Pei Kung, PhD, Associate research fellow of Pfizer
16:20-16:50 TOPIC: Therapeutic Discovery and Technology Development with the X-Chem
DNA-Encoded Chemistry Platform
Anthony Keefe, PhD, Vice President of Discovery Technology, X-Chem Pharmaceuticals
16:50-17:20 Panel Discussion - Speakers: Barry Morgan, PhD, Chief Scientific Officer, HitGen Xiaojie Lu, Professor, Principal Investigator, Shanghai Institute of Materia Medica Xiaoyu Li, Professor, University of Hongkong
Robert Goodknow, PhD, VP, Innovation Chemistry, Pharmaron
17:20-17:30 Closing Remarks
18:00-20:00 Closing Dinner – PLACE （TBD）
It is free event but we do provide paid catering service. Visit our websites to help you confirm your online
registration no later than Oct 15, 2018.
www.innovativedrugdiscovery.com/
8th-symposium-on-dna-encoded-chemical-library.eventbrite.hk
Chengdu Marriott Hotel Financial Centre
Add: No 999 TianFu Avenue North, High-Tech Zone, Wuhou, 610041 Chengdu, China
Tel: +86-28-88088888
Chengdu Shuangliu International Airport: 9.3 miles
Subway: Get off atJinrongcheng Station, 800 m from the symposium spot
Bus: 74, 118, 220, 501, 504, 506, 898, G32 are all available to arrive atsymposium
REGISTRATION
VENUE & TRANSPORTATION
FOR REGISTRATION & MEDIA
Contact Haiying Xue at [email protected] OR CALL (86) 28 85197385-8803.
FOR PRESENTATION
We will have 30 talks for both symposiums. If you would like to apply to be a speaker, please kindly send
your materials (applicant’s name, title, contact information, biography, company name, company
introduction, topic, abstract and high-resolution picture) to [email protected] no later than August 15,
2018 OR CALL (86) 28 85197385-8805 for more information.
FOR One-on-One MEETING &ROAD SHOW
If you would like to apply for a road show, please kindly send your materials (applicant’s name, title,
contact information, biography, company name, company introduction, project introduction ) to
[email protected] no later than August 15, 2018 OR CALL (86) 28 85197385-8701 for more information.
FOR POSTER & SPONSORSHIP
Contact Ning Ding at [email protected] OR CALL (86) 18102309666.
FOR INVITATION LETTER FOR VISA APPLICATION
If you would like to have invitation letter for visa application, please kindly contact Shelly He at [email protected]
OR CALL (86) 28 85197385-8805 for more information.
CONTACT US
