2017 Workshop Molecular Genetics of Hematopoietic …Benjamin Ebert, MD, PhD Brigham & Women’s Hospital and Harvard University, Boston, MA “Clinical Significance of Somatic

Society for Hematopathology/ European Association for Haematopathology

ASCP/SH DayWednesday, Sept. 6See p. 5 for details.

September 7-9, 2017Hyatt Regency ChicagoChicago, IL

Molecular Genetics of Hematopoietic Neoplasms

2017 Workshop

www.ascp.org/sh2017

Early Bird Ends June 30 - Register today and SAVE!

Society for Hematopathology/European Association for Haematopathology

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Program Overview

The use of genetic testing in the diagnosis and management of he-matopoietic malignancies is rapidly evolving. The goals of this work-shop are to share up-to-date information on the genetic features of hematologic diseases and the impact of genetic testing on the clini-cal diagnosis and classification of myeloid and lymphoid neoplasms. The Workshop will consist of a series of case presentations organized around specific topics as well as keynote lectures and an interactive roundtable discussion on the current challenges in implementing of genetic testing in hematopathology.

Program Committee

Olga Weinberg, MDBoston Children’s Hospital

Robert Hasserjian, MDMassachusetts General Hospital

Frank Kuo, MD, PhDBrigham and Women’s Hospital

Workshop Review Panel

Daniel Arber, MDUniversity of Chicago

Magdalena Czader, MD, PhD Indiana University

Falko Fend, MDUniversity of Tübingen



Megan Lim, MD, PhDUniversity of Pennsylvania

Miguel Piris, MDHospital Universitario Fundación Jiménez Díaz


The SH workshop is being held in conjunction with the ASCP annual meeting. This allows you to attend certain ASCP meeting functions in addition to this workshop. Please see schedule and additional registration option details enclosed.

September 7-9, 2017Hyatt Regency ChicagoChicago, IL

Molecular Genetics of Hematopoietic Neoplasms

2017 Workshop


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Round Table Panelists

Adam Bagg, MDUniversity of Pennsylvania


Annette Kim, MD, PhDBrigham and Women’s Hospital

Janina Longtine, MDYale University

Keyur Patel, MD, PhDUT MD Anderson Cancer Center

Jeremy Segal, MD, PhDUniversity of Chicago

Session Chairs

Daniel Arber, MDUniversity of Chicago

Nathanael Bailey, MDUniversity of Pittsburgh

Katherine Calvo, MD, PhDNational Institutes of Health

Magdalena Czader, MD, PhDIndiana University

David Czuchlewski, MDUniversity of New Mexico


Marian Harris, MD, PhDBoston Children’s Hospital


Todd Kelly, MDUniversity of Utah

Rebecca King, MDMayo Clinic


Megan Lim, MD, PhDUniversity of Pennsylvania

Elizabeth Morgan, MDBrigham and Women’s Hospital

Valentina Nardi, MDMassachusetts General Hospital

Miguel Piris, MDHospital Universitario Fundación Jiménez Díaz


Educational Objectives

After attending the conference, participants should be able to:

• Appraise the current WHO categories of myeloid and lymphoid neoplasms and identify areas of diagnostic difficulty (Knowledge, Competence, Performance)

• Utilize molecular diagnostic findings to aid in the differential diagnosis of myeloid and lymphoid disorders (Knowledge, Competence, Patient Care)

• Incorporate molecular genetic approaches in monitoring of patients with myeloid and lymphoid disorders (Knowledge, Competence, Performance, Patient Outcomes)

Target Audience

This conference is designed for physicians and other health profession-als in hematopathology, pathology, molecular diagnostics, cytogenetics, hematology and oncology.

Educational Methods

Lectures, Case Studies, Questions and Answers, Round Table Discussion

Evaluation

A course evaluation form will provide participants with the opportunity to comment on the value of the program content to their practice deci-sions, performance improvement activities, or possible impact on patient health status. Participants will also have the opportunity to comment on any perceived commercial bias in the presentations as well as to identify future educational topics.

Accreditation/Credit Designation

The Society for Hematopathology in partnership with the American Society for Clinical Pathology designates this live activity for a maximum of 19.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The American Society for Clinical Pathology is accredited by the Accredi-tation Council for Continuing Medical Education to provide continuing medical education for physicians.


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Featured Speakers & Topics

Elias Campo, MD, PhD Hospital Clinic and University of Barcelona, Barcelona, Spain

“Molecular Genetics of Small Mature B-cell Lymphomas”

Eric Duncavage, MD Washington University, St Louis, MO

“Fundamentals of Next-Generation Sequencing: Technologies and Applications”

Benjamin Ebert, MD, PhD Brigham & Women’s Hospital and Harvard University, Boston, MA

“Clinical Significance of Somatic Mutations in Hematologic Neoplasia”

Kojo Elenitoba-Johnson, MD University of Pennsylvania, Philadelphia, PA

“Novel Insights in the Molecular Pathogenesis of T-cell Lymphomas”

Lucy Godley, MD, PhD University of Chicago, Chicago, IL

“Genetic Predisposition Syndromes in Myeloid Malignancies”

Frank Kuo, MD, PhD Brigham and Women’s Hospital and Harvard University, Boston, MA

“Fundamentals of Next-Generation Sequencing: Analysis and Interpretation”

Megan McNerney, MD, PhD University of Chicago, Chicago, IL

“Therapy-Related Myeloid Neoplasms: When Genetics and Environment Collide”

CME Certificates and Attendance

Verification Certificates

Certificates awarding AMA PRA Category 1 Credit or certificates documenting attendance will be distributed to participants when the par-ticipant departs the conference. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verifi-cation Form. Upon request, a record of attendance (certificate) will be provided onsite to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other profes-sional associations.

SAM Credits

The Society for Hematopathology is partnering with the American Soci-ety for Clinical Pathology to provide American Board of Pathology (ABP) approved Self-Assessment Module (SAM) credits. SAM credits are neces-sary to meet the ABP maintenance of certification requirements. SAM credits will be available for this conference.

Types of Cases Featured in the Workshop

• Hematopoietic neoplasms in which genetic findings clarify the diagnosis, including new and provisional entities in the revised WHO Classification

• Hematopoietic neoplasms with unusual or unexpected genetic findings• Hematopoietic neoplasms in which genetic testing

results reveal the underlying disease biology• Molecular genetic evolution in hematopoietic

neoplasms after therapy or upon progression• Germline mutations predisposing to the

development of hematopoietic malignancies• Clonal hematopoietic conditions revealed by genetic testing,

including clonal hematopoiesis of indeterminate potential (CHIP), clonal cytopenia of undetermined significance (CCUS), and clonal T, B and NK lymphoid proliferations.

WEDNESDAY, SEPTEMBER 6 – ASCP/SH DAY AT ASCP 2017

6:00am – 7:00pm Registration Open for ASCP and SH Meetings

Hyatt Regency Chicago - Grand Ballroom Registration Desk

8:00am – 11:10am ASCP Educational Sessions • 8:00am – 9:30am • 9:40am – 11:10am

8:00am – 11:10am Plaza Ballroom Acute Myeloid Leukemia MATTERS: A Multidisciplinary Approach To Testing and Diagnosis, Evaluation of Risk, and Personalized Treatment Selection

11:00am – 7:00pm Exhibit Hall Open

11:00am – 12:00pm Poster Viewing & Judging

11:30am – 12:30pm Lunch Roundtable Session

11:30am – 1:00pm Lunch (Exhibit Hall)

1:00pm – 2:30pm Plaza Ballroom Improving MDS Outcomes from Diagnosis to Treatment: A Multi-Disciplinary Approach

1:00pm – 4:10pm ASCP Educational Sessions • 1:00pm – 2:30pm • 2:40pm – 4:10pm

4:15pm – 5:30pm ASCP Grand Opening General Session

5:30pm – 7:00pm ASCP Grand Opening Reception in Exhibit Hall

THURSDAY, SEPTEMBER 7 – SH 2017 WORKSHOP DAY 1

8:00am – 8:10am Welcome Olga Weinberg, Robert Hasserjian, Frank Kuo8:10am – 8:40am Genetic Predisposition Syndromes in Myeloid Malignancies Lecture: Lucy Godley Chairs: Olga Weinberg and Katherine Calvo

Session 1: Germline Predisposition Syndromes Chairs: Olga Weinberg and Katherine Calvo

8:40am – 8:50am Session Introduction8:50am –10:15am Oral Presentations 10:15am – 10:35am Session Summary

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ASCP 2017 Annual Meeting: Join us for SH Day!

For only $299 additional, get access to the Wednesday sessions at ASCP featuring a full day of hematopathology content presented by both organizations.

Add Wednesday, September 6 for only $299 before 6/30/17

10:35am – 11:00am Break11:00am – 11:30am Fundamentals of Next-Generation Sequencing: Technologies and Applications Lecture: Eric Duncavage11:30am – 12:00pm Molecular Genetics of Small Mature B-cell Lymphomas Lecture: Elias Campo Chairs: Miguel Piris and Rebecca King12:00pm – 1:30pm Seattle Genetics Lunch Symposium: Lymphoma Pathogenesis as the Ultimate Diagnostic and Therapeutic Guidance

Session 2: Genetic Testing in the Diagnosis of Lymphoid NeoplasmsChairs: Miguel Piris and Rebecca King

1:30pm – 1:40pm Session Introduction1:40pm – 3:05pm Oral Presentations 3:05pm – 3:25pm Session Summary

3:25pm – 3:45pm Break

3:45pm – 4:15pm Fundamentals of Next-Generation Sequencing: Analysis and Interpretation Lecture: Frank Kuo Chairs: Daniel Arber and Marian Harris

Session 3: Genetic Testing in Diagnosis of Acute Leukemias Chairs: Daniel Arber and Marian Harris

4:15pm – 4:25pm Session Introduction4:25pm – 5:50pm Case Presentation 5:50pm – 6:10pm Session Summary

6:30pm – 7:30pm Nanostring Evening Symposium

FRIDAY, SEPTEMBER 8 – SH 2017 WORKSHOP DAY 2

8:00am – 8:30am Clinical Significance of Somatic Mutations in Hematologic Neoplasia Lecture: Benjamin Ebert Chairs: Robert Hasserjian and Todd Kelley

Session 4: Genetic Testing in the Diagnosis of Myeloid Neoplasms (Excluding Acute Leukemias)Chairs: Robert Hasserjian and Todd Kelley

8:30am – 8:40am Session Introduction8:40am – 10:05am Oral Presentation10:05am – 10:25am Session Summary

10:25am – 10:45am Break

Session 5: Pre-Malignant Clonal Hematopoietic ProliferationsChairs: Frank Kuo and Valentina Nardi

10:45am – 10:55am Session Introduction10:55am – 12:10pm Oral Presentations 12:10pm – 12:30pm Session Summary

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12:30pm – 2:00pm Archer Diagnostics Lunch Symposium 2:00pm – 3:00pm Regulation, Reimbursement, and Reporting of Molecular Genetic Testing in Hematologic Neoplasms Round Table Discussion Panelists: Adam Bagg, Falko Fend, Annette Kim, Janina Longtine, Keyur Patel, Jeremy Segal3:00pm – 3:20pm Break

Session 6: Genetics Revealing the Biology of Myeloid Neoplasms (Excluding Acute Leukemias)Chairs: Falko Fend and Elizabeth Morgan

3:20pm – 3:30pm Session Introduction3:30pm – 4:45pm Oral Presentations 4:45pm – 5:05pm Session Summary

6:30pm SH Gala Reception Dinner

SATURDAY, SEPTEMBER 9 – SH 2017 WORKSHOP DAY 3

8:00am – 8:30am Therapy-Related Myeloid Neoplasms: When Genetics and Environment Collide Lecture: Megan McNerney Chairs: Magdalena Czader and David Czuchlewski

Session 7: Genetics Revealing the Biology of Acute Leukemias Chairs: Magdalena Czader and David Czuchlewski

8:30am – 8:40am Session Introduction8:40am – 9:55am Case Presentation 9:55am – 10:15am Session Summary 10:15am – 10:35am Break

10:35am – 11:05am Novel Insights into the Molecular Pathogenesis of T-cell Lymphomas Lecture: Kojo Elenitoba-Johnson Chairs: Megan Lim and Nathanael Bailey

Session 8: Genetics Revealing the Biology of Lymphoid Neoplasms Chairs: Megan Lim and Nate Bailey

11:05am – 11:15am Session Introduction11:15am – 12:30pm Oral Presentations 12:30pm – 12:50pm Session Summary

12:50pm – 1:05pm Workshop Summary and Closing Remarks Olga Weinberg, Robert Hasserjian, Frank Kuo, Daniel Arber

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2017 Workshop Molecular Genetics of Hematopoietic Neoplasms

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Registration Information

The American Society for Clinical Pathology – ASCP, see www.ascp.org, is managing and hosting the SH/EAHP 2017 Workshop in association with the ASCP 2017 Annual Meeting. ASCP is providing an option to add-on access to the ASCP program for activities outside of SH Workshop times.

For more information about any aspect of the SH/EAHP 2017 Workshop, please contact Nilda Barrett, at 1.312.541.4999 x4944 or by email at [email protected]

Early registration pricing is available until 6/30/2017. Advance registration is encouraged.

The full conference registration fee includes the tuition, conference materials, breaks, lunches, and one gala dinner. Guests may be added to the gala dinner for an additional fee.

There are three ways to register for the workshop:

Online registration at www.ascp.org/sh2017 is preferred. You will receive im-mediate email receipt confirmation.

1. Mail to: The Society for Hematopathology, C/O ASCP, 3462 Eagle Way, Chicago, IL 60678

2. Call ASCP Customer Service at: 1.800.267.2727 (Toll-free) 312.541.4848 (International Customer Service) Fax 312.541.4472

We accept the following forms of payment:

• Check (payable through U.S. banks only)• Money Order• Credit Cards (MasterCard, VISA, and American Express)

Refund/Cancellation Policy

A full refund will be issued for cancellations received in writing no later than August 22, 2017. Refunds are not issued for cancellations after this date. ASCP reserves the right to cancel a program due to circumstances beyond its control or for insufficient registration. Registrants will be notified immediately and allowed to substitute a session or obtain a full refund. The Society is not responsible for penalties incurred as a result of cancelled transportation. Please notify us in advance by contacting ASCP Customer Service at 800.267.2727, option 2; international callers: 312.541.4890; or www.ascp.org/feedback.

2017 Workshop Molecular Genetics of Hematopoietic Neoplasms

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6:30pm - 7:30 pm Cocktails

7:30pm - 9:00 pm Dinner

9:00pm - 10:00 pm Dancing

Airports & Ground Transportation

Chicago is served by two main airports• O’Hare International Airport, Chicago, IL

(18mi/45minutes from Downtown)• Midway Airport, Chicago, IL (12mi/35minutes from Downtown)

Meeting Facility

The SH-EAHP 2017 Workshop will be held Thursday – Saturday, September 7-9, 2017 in Chicago, IL, USA at the Hyatt Regency Chicago.

The ASCP Annual Meeting will also be held at this location from Wednesday– Friday this same week.

Accommodations

The host hotel for the 2017 SH/EAHP Workshop is the Hyatt Regency Chi-cago. The Hyatt Regency is located at 151 East Wacker Drive in Chicago, IL. See www.hyattregencychicago.com.

It is conveniently located near Chicago’s famous Magnificent Mile, Hyatt Regency Chicago is surrounded by downtown’s premier landmarks and attrac-tions. In an easy walk or short cab ride from the hotel, guests are linked to the city’s best shopping, cuisine, museums and theater.

Room Reservation

We have secured a room block to accommodate our SH/EAHP guests. It is very important that you stay at the HYATT REGENCY to receive the prefer-ential pricing we have secured. The Hyatt Regency hotel group rate pricing will be available until July 31, 2017, so please book early to assure your reservation using the link on the Workshop website.

Reception & Dinner

A Gala Reception dinner will be held at the Hyatt Regency Hotel on Friday evening, September 8, 2017.

One ticket to this event is complimentary with your workshop registration.

Guests may be added at the cost of $125 each.

Workshop Website

Please continue to visit the SH/EAHP 2017 Workshop website at www.ascp.org/sh2017 for continuously updated information about this meet-ing, including information about: Educational program; registration; confer-ence faculty; hotel and gala dinner.


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2017 Workshop Registration – September 7-9, 2017

ASCP/SH Day – Wednesday, September 6!For only $299 additional, get access to the Wednesday sessions at ASCP 2017, also located at the Hyatt Regency Hotel. Includes access to ASCP/SH Day on Wednes-day, September 6, featuring a full day of hematopathology sessions, including:

• Acute Myeloid Leukemia MATTERS: A Multidisciplinary Approach To Testing and Diagnosis, Evaluation of Risk, and Personalized Treatment Selection

• Improving MDS Outcomes from Diagnosis to Treatment: A Multi-Disciplinary Approach

• 2017 Who Classification-Hematopoietic & Lymphoid Tumors: Evolving Concepts, Relevant Testing, Directed Treatment in Lymphoma: Part 1 Basic Knowledge

This is not a self-mailer

Address to:The Society for HematopathologyC/O ASCP3462 Eagle WayChicago, IL 60678

Make check or money order payable to:The Society for Hematopathology

Registration FeesSH/EAHP Members

$649 Rate until 6/30/17 $699 Rate on or after 7/1/17

Non–Members $699 Rate until 6/30/17 $749 Rate on or after 7/1/17

Trainees $449 Rate until 6/30/17 $499 Rate on or after 7/1/17

Dinner Guest FeeGuests for Gala Reception and Dinner

$125 per Guest # of Guests

Participant Information

TOTAL Payment

$

ASCP 2017 RegistrationIncludes access to:• ASCP/SH Day, Wednesday, September 6• All ASCP 2017 Educational Sessions• Keynote and General Sessions• Welcome Reception Wednesday, September 6• Exhibit Hall

$299 (before 6/30/17)

Payment Information

Documents

2017 Workshop Molecular Genetics of Hematopoietic …Benjamin Ebert, MD, PhD Brigham & Women’s Hospital and Harvard University, Boston, MA “Clinical Significance of Somatic