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1995 11 5,000
3502015 9 10
3085 61.7% 3076 52.3% 43.3
3. 61.5% 2013 85.8% 201556.9%
4. 1.5% 1.0% 0.5% MDMA0.1%0.1% 0.3% 2.4%
5. 47.9 41.3 44.1 MDMA40.0
45.4 45.7 40.8 45.56. 138 95 50
12 MDMA 12 312013
7. 9394 MDMA 42 58
8. 1 34.3% 1995 62.9% 2015
- 7 -
3 1.6% 1999 2.5% 2015 9. 1 1995 4.0% 2007 7.7
2015 6.1% 2007 2.7%2011 1.9% 2015 2.9%
1
20%
MDMA2013
MDMA
258
160%
26 7
1990 19921,100 1993
3,000 19943,300
1-3 1995
114-13
2014 9 10 1
14)
- 8 -
2,297 20155
2014 12
2015
5,000 ( 350) 2
2015 9 10 10 4
15 645000
1) 11
2) 65 A
23
21 20 11 10 11 10 11
11 27 4
126 1
1
15 6480,038,406
3) 5,000 65
10 16
4) 122
11
2
1 = 15
64
5) 22
- 9 -
6)
2
15 64
A2014-149
41)
2) 1 30
3) 1 30
4)
4
121) Prevalence
prevalence
prevalence1~6
2) 7 133) 14 204)
21 275) 28346) 35 417) 42488)
49 559) 56
6210)
63 6911)
70 7612)
77 8313) 2~33 84 91
- 10 -
30
(1) NSAIDs(2)
/(3)
®
2) 1211 10 60
7 7/
/
2 t 3ANOVA
15
5,000 3,08561.7% 1915
45.8%31.3% 10.9%
B42.9%
49.1% 8.2%13.2% C
60 63.2% 20 31.5%
2038.7% 60 18.9%
2018.1% 60 5.7%
D
61.2% 58.7%35.0% 35.7%
37.2%35.7% 35.6%
14.6% 17.2%
1 1995 20151995 78.9%
2003 70%2005 60%
2007 2013 50%60%
76 403076
5247
5076
7 1347
30.8%52.3% 47.7%
43.3 4024.4% 50 22.6% 30
18.0% 45.7%14.2% 12.8%
38.6%30.2%
13.2%6.9%
68.1%2.7%
1
- 11 -
25.6%5 13.8%
6 1420 93.8%
1 80.2% 30 67.0%30
70.9%61.3% 75.0%
59.7%20 76.7% 10 14.9%
3079.4%
81.8%1 2
72.0%59.8% 1
26.2% 30 23.2%30
33.6%21.3%
37.9% 11.8%30 29.1%
10 2.7% 30
36.3%51.5%
45.0% 22.8%
31.2%
21 2771.3% 55.6%
55.3% 164.7%
63.0% 37.1%
5, 28 341 62.9%
30 26.9%3 2.3%
4.5%1.5%
1.5% 3.0%2.0% 60 3.6%
5.1%3.4%6.2%
4.7% 2.3%
3.3%
39.3%25.7%
12.9%0.9% 0.1%
39.5% 10.9%
39.8%30
97.9%0.6%
5, 35 411
5.6% 30 4.2%3 3.0%
5.7% 1.3%1.3% 3.4%
2.8% 604.0%
12.3%6.2%
5.7% 2.9%
- 12 -
5.1%
4.4% 0.1%
3.2%2.2% 1.5%
0.03%
82.3%6.5%
5, 42 481 6.1%
30 4.3% 32.8%
3.8%0.6%
3.4% 2.4%60 5.1%
11.2%5.7%
7.1%2.6%
5.1%
4.5%0.1%
5.1%0.03%
80.9%
6.7%30
3.9%
495596.1% 93.2%90.5% 88.0% 87.4%
4.4% 5.3%
97.9% 96.0%92.3% 78.5%
78.0%60.8%
89.9%
82.7%
1.2%
89.9%
0.7%
1, 56 620.4%
0.3% 1
0.3%0.2% 0.1%
1.5%
0.5%0.2% 30 0.7%
0.5%3.1%
0.9%
- 13 -
0.3%5
0.9%85.8%
56.9%
76.5%77.8%
52.3%61.9% 10
49.1% 60 62.6%
60.7%50.0%
66.5%46.9%
65.2%46.9%
57.2%35.5% 5.8%
1.1%
2,4, 63 69
2.4%2.0% 1.0% MDMA 0.6%
0.2% 0.2%0.6% 4.1%
3.1% 0.5%0.7% 30 1.4%1.0%1.5%
1.9%2 3 1.1%
4.5% 2.7% 2.5%MDMA 1.4% 1.3%
1.2% 1.6%5.9%
3.1% 1.0%2.1% 20 30
2.4% 2.4%3.1%
1.9%3 5
2.5%
3, 70 76
52.4% 14.6%13.1% MDMA 13.0%
11.5% 11.1%21.8% 53.5%
25.0% 18.2%22.2% 60 11.2% 3024.1% 13.4%23.2% 18.0%
33.3%5 25.3%
1, 77 83 E1
1.5%1.0% 0.5% MDMA 0.1%
0.1% 0.3%2.4%
- 14 -
47.941.3 44.1 MDMA40.0
45.4 45.740.8 45.5
1 0.1%0.1% 0.0% MDMA 0.0%
0.0% 0.0%0.0% 0.1%
2,3, 84 11 2011 85.0%
2013 81.9% 2015 79.8%10 1
10 1 200750.6%
2015 25.2%4,5
2009 66.4%65.0% 2011 64.0%
2013 59.8% 201520
20 200171.2% 42.9%
20156,7 84 1
1 2001 36.0%2015 26.9%
10 2013 2.6%2015 4.5%
8,9, 851
34.3% 199562.9% 2015
31.6% 1999
2.5% 201510,11, 85
1 2007
2.6%1999 2.9% 2013 3.1% 2015
12,13, 851 1995 4.0%
2007 7.72011 5.6% 2015 6.1%
2007 2.7%2011 1.9% 2015 2.9%
14,15
2.9% 2009 2.8% 20112.4% 2013 1.5% 2015
20132015
16,17
1.7% 2009 1.4% 20110.9% 2013 0.8% 2015
2013 201520 50 60 10
3018
1
2013 2015
19
- 15 -
20.1%51.5% 2 2031
32, 86,87
2013 20150.9% 1.0% MDMA 0.4% 0.6%
33, 89,900.4% 2013
0.3% 20151.9% 1.5% 1.1% 1.0%
MDMA 0.3% 0.1%
87
229191 94
16 20MDMA 58 52
201393 94 MDMA
42 58
90
138 9550
12 MDMA 1231
2013
2013 50%61.7%
47 3085
1995
0.4% 20130.3% 2015 1
0.1% 2013 0% 2015
31 201340
- 16 -
2,297 2015 5
61.5% 2013 85.8% 2015
56.9%
20%
5
MDMA 2013
MDMA
90
20132015 10 30
MDMA
1 62.9%1 2007
BZBZ
etizolam flunitrazepamtriazolam
14) 3
30
0.6% BZ 3.9%
- 17 -
12,297 2015 5
20%
1) 4
4pp.9-23, 1993.
2) 5
5pp.5-26, 1994.
3)6
6pp.5-34, 1995.
4)
7
7 1 pp.5- 35, 1996.
5)
9
9 1 pp.7- 48, 1998.
6)11
pp.17-70, 2000.3. 7)
13
pp.15-77, 2002.3. 8)
15
pp.17-87, 2004.3.
9)17
pp.17-105, 2006.
- 18 -
10)19
pp.15-95, 2008. 11)
(2009 ) 21
pp.15-95, 2010.
12)(2011
23
pp.15-95, 2012. 13)
2013 25
17-94,2014. 14)
26
95-128,2015.
1)
YAKUGAKUZASSHI 136(1) 79-872016.
2)37 6 4
8 2015. 3)
. Be! 120 , , ,
p42-47, 2015. 4)
26 1 44-49 2015.
1)
S52
1352015.3.25-28.
H.
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A
1 1995-2015
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B
C
D
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2 1 2005-2015
3 1 2005-2015
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4 1999-2015
5 1999-2015
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6 1 2001-2015
7 1 2001-2015
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8 1 1995-2015
9 1999-2015 3
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10 1 1995-2015
11 1999-2015 3
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12 1 1995-2015
13 1999-2015 3
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14 2009-2015
15 1999-2015
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16 2009-2015
17 1999-2015
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18 1 1995-2015
19 1999-2015
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20 1999-2015
21 1999-2015
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22 1999-2015
23 1999-2015
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24 1999-2015
25 1999-2015
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26 1999-2015
27 1999-2015
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28 1999-2015
29 1999-2015
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30 MDMA 1999-2015
31 MDMA 1999-2015
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32 1995-2015
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33 1995-2015
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