2015-2016 STEWARDSHIP REPORT...12 Pennington Biomedical Research Foundation STEWARDSHIP REPORT 2015-2016 13 multi-million dollar grant to establish an NIH center of excellence. For

STEWARDSHIP REPORT 2015-2016 3

2015-2016 STEWARDSHIP REPORT

Pennington Biomedical Research Foundation STEWARDSHIP REPORT 2015-20164 5

TABLE OF CONTENTSLetter from the Chairman 4

Letter from the Executive Director 5

About Pennington Biomedical 7

Leveraging Philanthropy 8

Finding Answers for Future Generations 12

Honoring Philanthropy and Service 14

Leaving a Legacy 16

Basic Science: Annadora Bruce-Keller, Ph.D. 20

Clinical Science: Daniel Hsia, M.D. 23

Population and Public Health Science: Robert L. Newton Jr., Ph.D. 26

Disrupting Diabetes 30

Endowments for Science 38

Volunteer Leadership 40

Honoring Lifetime Giving 42

Legacy Society 48

Council of 100 49

Annual Giving 50

Pennington Biomedical Research Foundation Staff 53

The Answer 2016 54

The Scientific Dinner Series 56

The Irene W. Pennington Women’s Wellness Day 56

Pennington Biomedical Employee Giving 56

Tributes in Honor and in Memory 58

Pennington Biomedical

Research Foundation

raises funds to support

Pennington Biomedical

Research Center in its quest

to discover the triggers of

chronic diseases through

innovative research that

improves human health

across the lifespan.

STEWARDSHIP REPORT 2015-2016Pennington Biomedical Research Foundation6

LETTER FROM THE EXECUTIVE DIRECTOR

As researchers, clinicians, employees

and community members, the staff of

LSU’s Pennington Biomedical Research

Center devotes our time and talent toward a

healthier state and global community.

We come to work each day inspired. We know the progress we make in the lab, in the clinic or in the community can lead to discoveries that help people in need.

I am incredibly grateful for your continued generosity. As donors and supporters of Pennington Biomedical, you help fuel the exploration of new ideas, innovative techniques and powerful technologies that not only benefit our friends and family at home, but people worldwide.

Through our research, we are

» understanding basic mechanisms of disease development

» evaluating individual response to nutrition and medical interventions

» evaluating studies impacting infant and maternal health

» helping kids find new and innovative ways to get and stay healthy

» engaging families to combat the obesity epidemic

» helping to develop key obesity and diabetes medications

William T. Cefalu, M.D.Executive Director

Pennington Biomedical Research Center

George A. Bray, Jr. Super Chair in Nutrition

When you give to Pennington Biomedical

Research Foundation, you are our partner in efforts

to discover the triggers of chronic disease and improve human health

across the lifespan.

—Dr. William T. Cefalu

C hances are you know someone who suffers from diabetes,

dementia, obesity or another challenging chronic disease.

It could be your child, parent, neighbor, best friend or even the guy whose stadium season tickets have been next to yours for a generation.

Louisiana leads the nation in the number of residents battling chronic diseases. So, everybody in the Bayou State is likely to know someone who is affected.

Rather than having our state’s name synonymous with poor health, what if Louisiana could be recognized as an innovator and leader in finding the solutions to the problems of chronic disease?

Our state could be a beacon of hope not only for our own citizens but for people throughout the United States and across the globe.

That is the reality and promise of Pennington Biomedical.

In only 30 years—a young age for a research institution—Pennington Biomedical’s world-renowned scientists have made miraculous discoveries that have improved the way Americans exercise, eat and think about chronic disease.

The pages of this report are filled with stories of its brilliant researchers and generous donors whose contributions allow scientists to explore new ideas, find innovative techniques and create powerful technologies.

We are grateful for the support of all of our donors, our board and our community.

Your continuous faith in the mission of Pennington Biomedical and your investment in research for a healthier Louisiana and a healthier global community is helping people everywhere live longer, better lives.

Thank you.

Jerry Jolly

LETTER FROM THE CHAIRMAN

J. Gerard “Jerry” JollyChairman Pennington Biomedical Research Foundation


ABOUT PENNINGTON BIOMEDICAL RESEARCH CENTER Pennington Biomedical Research Center puts science to work for a healthier Louisiana. A world research leader right here in Louisiana, our mission is to discover the triggers of chronic diseases through innovative research that improves human health across the lifespan.

At the forefront of medical discovery as it relates to understanding the causes of obesity, diabetes and dementia, Pennington Biomedical is a campus of Louisiana State University and conducts basic, clinical and population research.

The research enterprise at the Center includes approximately 57 faculty and more than 15 post-doctoral fellows who compromise a network of 45 laboratories supported by lab technicians, nurses, dietitians and support personnel, and 13 highly specialized core service facilities. The Center’s 450 employees perform research activities in state-of-the-art facilities on the 222-acre campus located in Baton Rouge, Louisiana. •

OVER 200 SCIENTISTS57 FACULTY 123 ADJUNCT 21 POST-DOCTORAL

APPROXIMATELY 207 ADDITIONAL RESEARCH ASSOCIATES, RESEARCH TECHNICIANS AND SUPPORT PERSONNEL

45 RESEARCH LABORATORIES

13 CORE FACILITIES

OVER 763,376 SQUARE FEET OF STATE-OF-THE-ART FACILITIES

» continuing to test and evaluate new treatments for disease

» working to optimize military performance and

» aiming to enable and promote healthy aging, including a search for solutions and treatments to dementia and other cognitive problems.

Our challenge is to keep moving the needle of health discovery forward. Funding for research from state and federal sources has been a significant challenge in recent years. Still, the need for science to find new and better ways to treat and prevent devastating diseases for our most vulnerable populations has never been greater.

Our friends at the National Institutes of Health note that chronic medical conditions—including cardiovascular disease, cancer and diabetes—cause more than half of all deaths worldwide, and in Louisiana we are all too familiar with them. Here at home, the rates of these three diseases far surpass national averages.

Despite the staggering data, our country currently spends less than five cents of each health dollar on research and development. Yet, it is progress through research that is helping us to imagine a future with drastically improved outcomes.

Imagine preventing obesity to preempt Type 2 diabetes and its complications, or research that leads to the ability to replace failing insulin-

producing cells. One day, we may have personal gene chips that can predict risk for high blood pressure, high cholesterol, diabetes, obesity, kidney and heart disease. Research is the key to progress.

These types of research activities are ongoing at Pennington Biomedical. When you give to Pennington Biomedical Research Foundation, you are our partner in efforts to discover the triggers of chronic disease and improve human health across the lifespan.

I would be remiss not to also thank several other partners including Louisiana Gov. John Bel Edwards and our legislature, LSU President Dr. F. King Alexander, the LSU Board of Supervisors, the Louisiana Board of Regents, the Pennington Biomedical Research Foundation and the Pennington Medical Foundation.

Your steadfast commitment to academic research and to our Center helps enable the research for which we are known the world over.

I am proud that Pennington Biomedical is a place of discovery focused on improving health, nutrition and chronic disease outcomes. You are a part of our success, and I hope that you will encourage others to join us as we work to continue advancing health discovery for generations to come.

Sincere thanks,

William T. Cefalu, M.D.


providing encouraging and welcome news to

health researchers like those at Pennington

Biomedical.

While it accounts for less than 25% of

Pennington Biomedical’s annual operating

budget, the State of Louisiana’s general fund

commitment is crucial, providing the essential

funding necessary to leverage donor support as

well as provide the “matching” funds required

to obtain federal research grants.

Gov. John Bel Edwards, legislators and other

key officials who recognized Pennington

Biomedical’s value to Louisiana intervened to

safeguard its budget during the most recent

fiscal crisis. By restoring $4 million for the

2016-17 fiscal year, these farsighted officials

signaled to Pennington Biomedical’s cadre of

stellar researchers that Louisiana recognizes

and values their contributions to improving

health outcomes not only for our state’s

population, but for our nation.

Combining philanthropic dollars with state

dollars and federal grants to provide scientific

knowledge, innovation and economic

development creates a stable foundation for a

highly desirable knowledge-based economy.

With support from the philanthropy of our

donors, state and federal grants to Pennington

Biomedical are bringing these assets to

Louisiana.

Our donors understand the economics as well

as the urgency and importance of Pennington

Biomedical’s contributions through research.

They recognize scientific research that advances

and improves health outcomes requires a

sustained investment, and new ideas in research

can often take decades to develop. So, they have

acted swiftly and often to bridge the funding

gaps and assure the best research ideas have a

chance to succeed.

For example, in 2005, the Coypu Foundation

donated $200,000 to create the John S.

McIlhenny Research Laboratory of Botanical

Research. Based on the science conducted

in this lab with this initial investment,

investigators at Pennington Biomedical were

able to submit and successfully obtain an initial

Charitable gifts from donors provide essential leverage that permits Pennington Biomedical researchers to acquire

federal and state funding. Philanthropy helps turn science into practical health solutions by supporting faculty researchers

and their projects.

In 2015-2016, Pennington Biomedical Re-

search Foundation provided more than

$3 million in program support that enabled

Pennington Biomedical Research Center to

leverage additional research funding for its

scientists to continue their amazing record of

productivity.

Pennington Biomedical is most financially

sustainable and globally competitive when

three elements of innovation are in alignment.

Those three pillars—people, facilities and

equipment—produce grants that make

Pennington Biomedical’s groundbreaking

research possible and provide the basis for

continued growth and success. Stability relies

on consistent funding support. Further, each

source of funding support—federal, state and

philanthropic—is highly dependent upon the

other.

Winning scarce federal grant dollars, the “gold

standard” in competitive research funding,

often requires a researcher conduct pilot

studies to develop the initial data necessary

to submit a federal grant application. Such

preliminary work often depends upon support

from philanthropic or state funding sources.

Essentially, these early funds are leveraged by

Pennington Biomedical into coveted federal

research dollars.

When any source increases funding, the

benefits are exponential and ripple throughout

the Pennington Biomedical research enterprise.

Conversely, when any source is reduced, the

adverse impact on Pennington Biomedical is

magnified because those dollars are no longer

available to be leveraged.

Unfortunately, during the past 12 years, a

decline in both federal research and state

operating funding streams have coincided.

These reductions have negatively impacted

research, even among Pennington Biomedical’s

most senior scientists. Recently, however,

the outlook for the National Institutes

of Health (NIH) budget has improved,

Pennington Biomedical is most financially sustainable and globally competitive when three elements of innovation are in alignment. Those three pillars—people, facilities and equipment—produce grants that make Pennington

Biomedical’s groundbreaking research possible and provide the basis for continued growth and success.

LEVERAGING PHILANTHROPY


multi-million dollar grant to establish an NIH

center of excellence. For more than a decade,

the botanical center has studied the effects of

plant extracts on human health and diseases.

This past year, the NIH renewed the botanical

center’s funding for a third time (through 2020)

with total funding to date of roughly $24.8

million. This example is only one of many

demonstrating successful return on investment

in science.

Charitable gifts from donors provide essential

leverage that permits Pennington Biomedical

researchers to acquire federal and state

funding. Their gifts help turn science into

practical health solutions by supporting

faculty researchers and their projects; enabling

exploration of the underlying causes of disease

and new treatments; and, by affording young

researchers an opportunity to blossom and

grow.

Philanthropy from our generous donors plays

a key role in accelerating scientific progress

and helps us to promote research that enables

longer, healthier lives for people everywhere. •

Pennington Biomedical Research Foundation is a nonprofit 501(c)3 organization. The 2015-2016 Pennington Biomedical Research Foundation audited financial statements are available online at www.PBRF.org.


Alzheimer’s research now is where cancer research was 30 years ago. I support the IDRP

because it’s trying to prevent and cure Alzheimer’s.

—John Kovich

John and Faye Kovich.

FINDING ANSWERS FOR FUTURE GENERATIONS

John Kovich made a career out of solving

problems.

For more than 34 years, the chemical engineer applied a combination of physics, chemistry, biology and mathematical principles to meet the daily challenges that arose in the operation of ExxonMobil’s Baton Rouge Chemical Plant.

So, when his wife, Faye, was diagnosed with early onset Alzheimer’s disease at age 53, John immediately looked to science to provide solutions.

While John had a basic knowledge of the disease from media coverage, “I was unaware there’s no treatment, prevention or cure,” he recalls. “So, when I heard the medicines just mask the symptoms and don’t do anything to slow the disease—as an engineer—I thought: That doesn’t sound right. Surely there must be something I can do; but, there wasn’t.”

Because John’s approach to problem solving was already grounded in the scientific method, pursuing participation in a clinical trial seemed the next logical step. While the Koviches were willing to go anywhere to get the expertise they sought, an expert in Chicago cautioned travel would get exponentially harder as the disease progressed.

Their search for a clinical trial close to home quickly led to Pennington Biomedical’s Institute for Dementia Research and Prevention (IDRP) and a meeting with manager Rob Brouillette.

While Faye did not qualify for any trials, John found the information culled from those evaluations and subsequent conversations with Brouillette to be invaluable in a difficult decision-making process.

Besides addressing the daily dilemmas regarding Faye’s care, John soon found himself trying to find answers for the next generation. Even though there’s not a strong genetic link, “My kids, my nieces and nephews all have this worry in the back of their minds. What can you tell them?” he asks.

“If heart disease runs in your family, you exercise and eat right. You do things to improve your odds. If colon cancer runs in your family, you get a colonoscopy. With Alzheimer’s, what can you do? Other than sit there and worry.”

John decided to take action by investing in the IDRP. “While Alzheimer’s is the sixth leading killer in the United States and the numbers are growing, the public hasn’t become outraged enough to make it a priority,” he explains. “So, Alzheimer’s research now is where cancer research was 30 years ago. I support the IDRP because it’s trying to prevent and cure Alzheimer’s.” •


Above: Kristin Britt (front row, from left), Paula

Pennington de la Bretonne, Peggy Cole, Kelly Love and

Shannon Smith. Dr. Dana Hart (back row,

from left), Harris Britt, Chris Blackstone,

Dr. Andrew Smith and Alyce Blackstone.

Right: Paula and Jacques de la Bretonne.

In February 2016, Pennington Biomedical Research Foundation, Pennington Medical Foundation, family and friends gathered to

recognize the leadership of Paula Pennington de la Bretonne. The event culminated with the dedication of the Paula Pennington de la Bret-onne Board Room in the Foundation office.

Gifts made in de la Bretonne’s honor are being used as seed money to support the exciting research of young scientific investigators.

“While I am honored by the recognition, the most important thing is how these contributions will be used to solve many of the chronic disease problems we face, not only in our community but worldwide,” says de la Bretonne.

“Family is everything to me. We all strive to be healthy in our own way,” she explains. “I hope that the research conducted at Pennington Biomedical will improve the health of families

throughout our community—and across the globe.”

For the past 36 years, the Baton Rouge philanthropist has carried on the legacy of her grandparents. The late C.B. “Doc” Pennington and his wife, Irene, presented LSU with the seminal gift that helped launch LSU’s Pennington Biomedical Research Center with the directive to create “the biggest and best nutrition research center in the country.”

Paula Pennington de la Bretonne is the only original trustee who still remains on the board of the Pennington Medical Foundation. Since 2003, she has served as board chair.

Jacques de la Bretonne, M.D., Paula’s husband, contributed the lead gift in her honor. Numer-ous friends joined in with contributions in honor of her service and dedication to biomedi-cal research. •

HONORING PHILANTHROPY AND SERVICE

All Star Automotive GroupDirectors and Advisors of Analytic Stress, Inc.Annette D. BartonMr. and Mrs. John W. Barton, Jr.The John W. Barton Family FoundationBaton Rouge Area FoundationBaton Rouge General Medical CenterBrenda and Lee Michael BergLori J. BertmanElizabeth and William CefaluDr. Claude Bouchard and Monique ChagnonMr. and Mrs. Gregory J. CotterMr. and Mrs. Tommy D. CowartCharles and Susan D’Agostino / ASRJack and Susan Dampf

Jacques A. de la Bretonne, M.D.Dr. and Mrs. Robert L. DelarosaEquitas Capital Advisors LLCJohn G. Turner and Jerry G. FischerRaising Cane’s and The Graves FamilyMr. and Mrs. G. Lee GriffinFran and Leroy HarveyDavid HerzogMr. and Mrs. Bill R. HiseMr. and Mrs. Brad JewellMr. and Mrs. J. Fred JohnsonMr. and Mrs. J. Gerard JollyJane and Kris KirkpatrickMr. and Mrs. Charles W. Lamar IIISusan and Richard LipseyDonald J. LoganDr. Donna H. Ryan and Edwin Lupberger

Brent and Sunny McCoyMr. Matthew G. McKayDalton J. MeauxMr. and Mrs. Ellis A. MichaelMr. and Mrs. Jake L. NettervilleVirginia B. and John B. NolandJanet L. OlsonClaude and Sharon PenningtonDaryl and Mary PenningtonIrene W. and C.B. Pennington FoundationThe Powell GroupSSA Consultants, Inc.Stephanie PitreBryan and Raymond G. Post, Jr.Dr. William E. Russell and Dr. Andrew LauveMr. and Mrs. William L. Silvia, Jr.Johnny and Diane TateJennifer and Chuck Winstead

We are grateful for the family and friends who made generous gifts to honor Paula Pennington de la Bretonne.


LEAVING A LEGACY

In 2016, the LSU Board of Supervisors unani-mously voted to award a Boyd Professorship to Claude Bouchard, Ph.D., the John W. Bar-

ton Sr. Endowed Chair in Genetics and Nutri-tion and professor and director of Pennington Biomedical’s Human Genomics Laboratory.

For nearly half a century, Bouchard’s research has contributed to the understanding of the genetics of obesity and the genetics of human biological adaptation to exercise. Bouchard has published more than 1,000 scientific papers and has written or edited more than 30 books. He has also been awarded 6 doctorates honoris causa from institutions in Canada, Europe and the U.S.

In the world of scientific research, Bouchard’s name is synonymous with groundbreaking obesity and exercise biology research. However, here in Baton Rouge, Bouchard is also widely recognized for something else—his commitment to philanthropy.

During his tenure as Pennington Biomedical’s executive director from 1999 to 2010, Bouchard frequently encouraged Pennington Biomedical staff to give of their time, talents and dollars for the betterment of other local organizations. Likewise, he inspired the community, donors and the state to invest in the growth of Pennington Biomedical. Years later, the community and the Center are still reaping the benefits of his philanthropic leadership.

Five years after returning to research full time, Bouchard and his wife, Monique Chagnon, remain just as determined to ensure the future

of Pennington Biomedical Research Center. While they are members of the Council of 100, the Bouchards have also decided to make a legacy gift.

During his career, Bouchard has trained, lectured and been honored at institutions around the world. Yet, Pennington Biomedical remains a special place to this internationally renowned researcher and his wife. Both Bouchard and Chagnon have worked at Pennington Biomedical.

“Monique and I are convinced of the value of philanthropy for all institutions—particularly public institutions because they tend to get less attention than the private ones,” he begins.

“When we arrived in Baton Rouge, we found a warm and welcoming community

In the world of scientific research, Bouchard’s

name is synonymous with groundbreaking obesity and

exercise biology research. However, here in Baton Rouge,

Bouchard is also widely recognized for something else—his commitment to

philanthropy.

Monique Chagnon and Dr. Claude Bouchard.


Not only does Pennington Biomedi-

cal have a worldwide reputation, the

Center recruits researchers to work

and live in the Capital City from across the

globe—as far away as Australia, Czechoslo-

vakia, France, Germany, Finland, China and

Russia and as close as Denham Springs.

Since the Center’s founding nearly 30 years ago, more than 5,300 publications have been attributed to Pennington Biomedical scientists. Those publications have been cited in the scientific literature by other authors and experts nearly 148,000 times.

Pennington Biomedical scientists are eager to share their scientific advances with colleagues worldwide. For example, basic science researchers have collaborated on more than 180 research projects with colleagues on other LSU campuses. They’ve also worked to identify and better understand the building blocks of chronic disease with institutions and companies around the world.

In addition, Pennington Biomedical faculty is training the next generation of biomedical researchers and academic physicians. Because of Pennington Biomedical’s international prestige in scientific circles, it’s no surprise the postdoctoral training program was voted among the Top 10 in the nation in The Scientist’s 2012 listings of Best Places to Work for Postdocs. The scientists also provide hands-on laboratory research training to scores of Louisiana undergraduate, graduate and medical students each year.

Your generous gifts advance their stellar research, so we’d like you to meet three scientists who have benefited from Foundation funding.

These scientists represent the disciplines of basic, clinical and population science. Their academic credentials are only eclipsed by their determination to make the world a better place by improving health across the lifespan of every person on the planet.

MEETING [OF] THE MINDS

These scientists represent the disciplines of basic, clinical

and population science. Their academic credentials

are only eclipsed by their determination to make

the world a better place by improving health across the lifespan of every person on

the planet.

and wonderful people with whom we have developed close friendships,” Chagnon explains. “It became important for us to give back to an institution that we cherish so much and to join other generous donors who believe as much as we do in the mission of the Pennington Biomedical.”

Even though Bouchard has long been associated with the Human Genomics Laboratory, the couple intends for their contribution to enter the unrestricted fund. “We are presenting this legacy gift to the Foundation to invest in partnership with the Center where it is strategically most useful,” he explains. “We plan to leave to the institution the final decision in allocating these funds where they will have the most favorable impact.”

During his tenure as the executive director and now as a faculty member, Bouchard believes in Pennington Biomedical’s untapped potential to make a significant difference in the health of people in Louisiana and around the globe.

“There are not many institutions that are totally invested in the broad field of preventing

common diseases associated with our way of life,” he says.

In addition, the couple considers Pennington Biomedical a sound investment.

“I know that Pennington Biomedical generates extraordinary value for the dollars invested,” Bouchard says. “The return is large and not only in terms of economic activities but in gains of knowledge and abilities to augment preventive medicine in both the public health and disease-specific contexts.”

Furthermore, “In Louisiana, Pennington Biomedical is one of the best places to invest because the pay-off is almost guaranteed,” he says. “It is a win-win. The investment will translate either in new knowledge that will improve disease prevention and prevent premature death or will result in the transfer of technologies that can contribute to the economy. But often, with the right investment at the right time, it is both.” •

The investment (in Pennington Biomedical Research Foundation) will translate either in new knowledge that will improve disease prevention and prevent premature

death or will result in the transfer of technologies that can contribute to the economy. But often, with the right

investment at the right time, it is both. —Dr. Claude Bouchard

STEWARDSHIP REPORT 2015-2016 23Pennington Biomedical Research Foundation

Dr. Annadora Bruce-Keller at the Redstick Farmers Market on Pennington Biomedical’s campus.

Since her research focuses on the bowel

and gastrointestinal tract, Annadora

Bruce-Keller isn’t on the A-list of local

lunch speakers. But, one day, her research might

be the talk of town as it influences the mainstay

of menus everywhere.

Over the past 20 years, Bruce-Keller’s interest in identifying and influencing factors that affect brain function have taken her far from where she started.

“Traditionally, neuroscience research for dementia or depression focuses on things going on in the brain,” she explains. “Those are all very important. But, I don’t think that’s all that matters.”

Bruce-Keller’s early work focused on understanding how HIV and diabetes increased the risk of developing dementia. Subsequent work to isolate the elements responsible for those brain changes led to a place where most neuroscientists loathe to go—deep within the abdominal cavity. The aim of her expedition was to determine whether micro-organisms in the intestines are important to brain health.

Because Pennington Biomedical encourages multi-disciplinary collaborations, Bruce-Keller found colleagues in genomics, nutrition and other specialties eager to pursue basic research in the microbiome.

“It’s exciting to work with all these other people because for the longest time, brain people only worked with brain people,” she says. “The microbiome research organically evolved

BASIC SCIENCE

ANNADORA BRUCE-KELLER, PH.D.Associate Professor, Inflammation and Neurodegeneration

Hometown: New Orleans, LA El Paso, TX

Education: B.S. Chemistry (Honors), University of Texas at El Paso, TX, 1990

Ph.D. Neurobiology, University of Southern California, CA, 1995

Recent Travel: New Orleans, LA to present research at the Obesity Society

A healthy microbiome can support a level of emotional resilience by making us feel

more energetic, less anxious, less depressed and even

sharper.

—Dr. Annadora Bruce-Keller


CLINICAL SCIENCE

DANIEL HSIA, M.D.Assistant Professor of Research,

Clinical Trials Unit

Associate Program Director, LSUHSC Endocrinology Fellowship

Hometown: Thibodaux, LA

Education: B.S. Rensselaer Polytechnic Institute,

(6 year Accelerated Biomedical Program), Troy, NY, 2000

M.D. Albany Medical College, Albany, NY 2004

Residency LSU Health Sciences Center, Internal Medicine/Pediatrics,

New Orleans, LA 2008

Fellowship Baylor College of Medicine, Adult and Pediatric Endocrinology,

Houston, TX 2012

Recent Travel: Vienna, Austria for an international

investigator’s meeting for a research study

Daniel Hsia has never been content to

follow the crowd, accept the status quo

or be bound by convention. Instead,

he prefers to set his own course, which has led

down an unconventional path.

As a fourth-year medical student, Hsia was vexed by the decision of which specialty to pursue for his residency. Most residency programs focus on the care and treatment of either adults or children.

“It didn’t make sense to me,” he says. “It’s important not to lose that connection between childhood and adulthood—especially for patients who have diabetes or other endocrinology disorders. These are all chronic diseases. Frequently, kids get diagnosed with diabetes and lose contact with their physician because they go to college or move away. They end up in the emergency room and/or not getting the amount of care they should. So, I walked into residency trying to be a bridge.”

Ultimately, Hsia began post-graduate training in LSU’s combined internal medicine/pediatrics program in 2004. When Hurricane Katrina shuttered New Orleans’ residency programs, Hsia leveraged his hometown connections to create residency positions at Leonard J. Chabert Medical Center in Houma, which houses its own robust program today.

After finishing a combined four-year fellowship, Hsia became one of the few physicians to earn board certification in four specialties—internal medicine, pediatrics, pediatric and adult endocrinology. While colleagues advised him

because a variety of us were kind of heading in that direction.”

That synergy of specialties soon led to the publication of a paper detailing how gut bacteria from a high-fat diet can lead to anxious, fearful and compulsive behavior in mice. With the connection between the microbiome and brain confirmed, Bruce-Keller is now exploring in how high-fat and high-calorie diets can detrimentally affect the brain with an emphasis also on aging and age-related dementia.

“This microbiome is a powerful system—just ask anyone who has clostridium difficile [a bacterial imbalance that cause irritation of the intestinal lining],” she says. “They have no energy, and they can’t get out of bed.”

Conversely, she believes the gut microbiome’s powers could be harnessed to help people perform at their best. “I feel that establishing a healthy microbiome through diet, exercise and other means can buffer against a lot of life’s unpleasantness,” she says. “It can utilize our food better and [support] a level of emotional resilience by making us feel more energetic, less anxious, less depressed and even sharper.”

The key to maximizing the benefits of the microbiome might be letting go of a little ego. “It’s kind of exciting from a philosophical perspective because your bowel is as far from your brain as you can get,” she says. “It’s interesting and humbling in a way. If you can get past that little bit of irony, it’s so hopeful.”

Individuals have little control over the pathways in their brains, their genes and the environment in which they live or work. However, Bruce-Keller says, “You can adjust your microbiome pretty easily with diet, pharmaceuticals, transplant, exercise or botanicals.”

She believes the key is to shift the emphasis from weight loss to healthy eating. “Weight loss is profoundly difficult [because] the body has very powerful mechanisms to defend its weight,” she explains. “If you begin a healthy diet because you want to change the number on the scale, it’s very easy to get discouraged.”

However, “If you’re eating a healthy diet to feel good,” she says, “you can easily change your microbiome by changing what you eat. For example, at lunch, you can have fruit, kefir and flax seed. Adjusting your diet is an actionable goal. It’s an easy, inexpensive way to promote feeling good.”

While the data is promising, Bruce-Keller knows translating promising scientific discovery to products and practice that make a significant impact on health is a long road. “You always think you know what’s going to make people better,” she says. “The issue is separating the hype from the details, so we’re being very careful and thorough in our analysis because it’s easy to jump to conclusions. We work hard to tangibly and immediately improve the health of people in this community and worldwide.” •


to focus on one specialty, Hsia was determined to apply his extensive training to the care of patients from birth through adulthood.

Even though Hsia was recruited by clinics and medical centers across the country, he found the perfect opportunity close to home.

Hsia had a typical Louisiana upbringing. His family frequently drove past Pennington Biomedical on their way to games at Tiger Stadium. Still, Hsia had no idea of the research conducted on the Perkins Road campus until he arrived for a job interview in 2012.

“It was the opportunity to delve into research and to work with Dr. Cefalu that brought me to Pennington Biomedical,” he says. “He is known as an expert in diabetes and as the editor of Diabetes Care; but, I know him as a supportive mentor and someone who genuinely cares about the trajectory of a young scientist’s career.”

At Pennington Biomedical, Hsia has a hybrid practice. As the Center’s only pediatrician, Hsia is the medical director for 10 research studies involving nearly 800 children.

To make sure that research remains relevant to the issues physicians face, Hsia maintains clinical practice at Our Lady of the Lake Children’s Hospital. There, he primarily treats teenagers and young adults with diabetes. At the Primary Care Plus Clinic, he also treats predominantly senior citizens.

While Pennington Biomedical’s clinic does not treat patients, Hsia’s clinical skills have saved lives by diagnosing a thyroid nodule in an

adult volunteer being screened for a study and a potentially life-threatening heart defect in a child among others.

Hsia’s own research focuses on preventing obesity and treating Type 1 and Type 2 diabetes in children. He also leads two National Institutes of Health (NIH) clinical trials. One study is evaluating the benefits of aspirin; another project investigates whether older adults who are prediabetic could benefit from taking Vitamin D. Hsia was recently awarded a $1.4 million grant from the NIH to establish a clinical trials site for studies involving everything from childhood asthma to obesity. This grant is a collaboration with Tulane University and opens the door to future NIH pediatric research studies for children across Louisiana.

In addition to his responsibilities at Pennington Biomedical, Hsia has become the associate program director of LSU’s Endocrine Fellowship, which provides post-graduate fellowship education of future endocrinologists.

“The greatest part of being at Pennington Biomedical is being able to develop my own path, see what my interests are and work with great people,” Hsia says. “We really target a lot of the problems and diseases that affect the people of Louisiana such as diabetes, obesity, heart disease, high blood pressure and high cholesterol. I feel like I’m giving back in some way all the great things the state has given me. It’s nice to come home and to do some important work that will help future generations.” •

Dr. Daniel Hsia examines Paul Carmichael.


cell phones and email accounts—of study

participants.

He found that and much more at Pennington

Biomedical Research Center.

“When I got here, the campus consisted of

only the administration building, basic science

building, clinic and conference center,” Newton

recalls.

However, “There were all these people—George

Bray, Eric Ravussin, Claude Bouchard—you had

read about but you never got to meet,” he says.

“There was a metabolic chamber, underwater

weighing and studies being conducted using the

Internet and computers [which were a novelty

then].”

Another attractive feature was the area’s

demographics. “Other places I could have

gone, I would have had to work very hard to

recruit my population for studies,” he explains.

“Baton Rouge was 50% African American. I

thought: If you can’t do research here, then you

can’t do research because it’s such a conducive

environment.”

Since coming to Baton Rouge just over 15 years

ago, Newton has road tested interventions at

colleges, YMCAs, churches and elementary

schools across the state. Many of Newton’s

studies investigate whether technology can be

used to motivate entire communities to get

physically active and make good nutritional

decisions.

A few years ago, Newton was involved in a

pilot study to investigate whether sending text

messages and behavioral strategies to parents

would prompt them to encourage their children

to exercise. The study resulted in the children

becoming more active. He’s now testing a

mobile phone app that directs college students

to find healthy cuisine nearby, increase activity

and sleep better.

Other research relies less on social media

than age-old social networks. Newton has

coordinated a weight loss program for church

members who are overweight and at risk for

developing diabetes. Pennington Biomedical

staff trained two health care professionals

from eight churches to educate and monitor

If we link these groups together, we can transform this city into one that has tons of resources to improve health and reduce the

risk of chronic disease for people of all ages.

—Dr. Robert L. Newton Jr.

D oes being a member of certain ethnic

groups physiologically predispose peo-

ple to be at higher risk of developing

certain diseases?

That question has propelled Robert Newton’s

research for nearly two decades.

The issue first arose when Newton participated

in an undergraduate summer program at Duke

University. While his mentor hypothesized

body type plays a major role in risk for

developing certain diseases; Newton theorized

the factors are societal and behavioral.

“If you don’t eat right and exercise, you’re going

to be susceptible to these kinds of conditions,”

he says. “When everybody else in your

environment looks the same and eats the same,

you don’t know any different.”

By the time he finished his Ph.D. in clinical

psychology, Newton had concluded studies

conducted in a laboratory or academic setting

that evaluated behavior changes didn’t provide

a true measure of the program’s effectiveness in

the real world.

To successfully conduct studies out in the

community, the junior investigator needed

seed funding for pilot programs that would

hopefully attract larger grants; proximity to a

large African American community to recruit

study volunteers; and, access to technological

interventions to deliver messages about healthy

behaviors directly right into hands—and

POPULATION AND PUBLIC HEALTH SCIENCE

ROBERT L. NEWTON JR., PH.D.Associate Professor, Physical Activity & Ethnic Minority Health

Hometown: Poughkeepsie, NY

Education: B.A., Psychology, Hampton University, Hampton VA, 1993

Ph.D., Clinical Psychology, University of Florida, Gainesville, FL, 2002

Recent Travel: Cape Town, South Africa to present the results of an exercise training program, which was designed by Newton and run by YMCA personal trainers, for African American men at risk for developing diabetes


members who improve their diet and increase

their physical activity. The program uses text

messages that offer encouragement and tips for

making healthy lifestyle changes.

In designing a dementia study for African

American seniors, Newton and Associate

Professor and Director of Biomedical Imaging

Owen Carmichael, Ph.D., are also consulting

with community members to determine the

types of activities and screenings that would be

attractive to potential study participants.

While his studies focus on African Americans,

Newton readily acknowledges information

gleaned from that research is applicable to the

general population.

“The work that I do has the potential to affect

large numbers of people because it’s community

based,” Newton explains. “It doesn’t exclusively

apply to African Americans. Anything we do in

the community applies to everybody.”

Over the years, Newton’s research has

demonstrated it’s possible to have a positive

impact on health through churches, YMCAs,

BREC, schools and community groups. “If we

can link these groups together as other cities

have done,” Newton says, “we can transform

this city into one that has tons of resources to

improve health and reduce the risk of chronic

disease for people of all ages.” •

Constance Mims (from left), Claudette Washington, Sherry Johnson, Dr. Robert Newton, Dolores Emerson and

Evelyn McNabb at Oasis Christian Church, where some of the church members volunteer for Dr. Newton’s studies.


Lab Manager Richard Carmouche (left) and Dr. J. Michael Salbaum run blood samples in the ddPCR.

In the Fall of 2015, the Edward G. Schlie-

der Educational Foundation presented a

$315,000 grant to Pennington Biomedical

Research Foundation. The funds were allocated

to purchase three pieces of highly sophisticated

equipment essential to cutting-edge research in

obesity and diabetes.

Since then, the fluorescent dissecting

microscope, ddPCR (digital droplet polymerase

chain reaction) and HPLC (high-performance

liquid chromatography) have provided

Pennington Biomedical scientists with the

ability to visualize genetic activity, measure

trace amounts of DNA and differentiate

biochemical compounds as never before.

With these tools, researchers have begun

exploring strategies that aim to prevent the

onset of diabetes and stop the disease’s horrible

progression. These new strategies could

eventually improve the lives of millions of

people worldwide who are currently battling or

at risk of developing diabetes.

Preventing birth defects in children of diabetic mothersBefore some women even know they’re

pregnant, diabetes can affect the lives of their

children.

While much is known about the risks of

gestational diabetes later in pregnancy, little

is known about how the mother’s diabetes—

usually undiagnosed and uncontrolled—

influences brain, spine, heart and other major

organ development in the earliest stages.

“Diabetes has a very crucial effect on

development of the unborn in the first three

weeks of life,” explains J. Michael Salbaum,

Ph.D., professor of Genomics and Regulation of

Gene Expression.

In preclinical studies, Salbaum’s lab scrutinizes

the genetic activity in embryos that results in

the abnormal formation of the neural tube,

the hollow structure from which the brain and

spinal cord form.

“We’re now using the ddPCR technology to

understand gene activities that are affected by

the diabetes of the mother,” he says, “so we may

develop a way to counteract those activities and

DISRUPTING DIABETES

This equipment allows us to detect earlier disease onset as well as to decide to intervene

earlier. That may allow a more preventative option to

be considered rather than the usual strategy of treating a disease that already exists.

—Dr. Jason Collier


illuminates fluorescent biomarkers that are

visible at a range of magnifications.

In the course of anatomical mapping,

Muenzberg-Gruening hopes to decipher how

to activate and inhibit the fibers’ function. “If

we can shrink or expand fat tissue or increase

metabolism in [the lab],” she says, “we could

design an intervention to encourage weight loss

or prevent weight gain in humans.”

Detecting early onset offers hope of halting diabetesLouisiana has one of the highest mortality

rates from chronic diseases. Nearly 35% of

Louisianians are obese, and diabetes has been

diagnosed in more than 10%. It’s no surprise

that nearly every family in Louisiana is either

directly impacted by or knows someone with

diabetes.

In the Islet Biology and Inflammation

Laboratory, Assistant Professor Jason Collier,

Ph.D., is exploring how inflammatory processes

in both Type 1 and Type 2 diabetes destroy

pancreatic beta cells, which regulate insulin

production and release.

Once beta cells are lost, individuals lose the

ability to make and secrete insulin. When that

happens, the level of glucose in the bloodstream

rises. Left untreated over time, it can cause

blindness, nerve and kidney damage.

Collier and his colleagues can now focus

attention on developing new approaches that

could either prevent the destruction of beta cells

or preserve the function of the remaining cells.

These studies could lead to new ways to treat

the disease that create fewer side effects and

help patients lead a better life.

In the past, the ability to detect when pancreatic

cell death occurs—particularly in humans—

was limited by the impossibility of taking a

pancreatic biopsy at various intervals in the

disease process.

Because it requires only a blood sample, “The

ddPCR allows us to detect earlier disease onset

as well as to decide to intervene at earlier time

points,” Collier explains. “That may allow a

more preventative option to be considered

rather than the usual strategy of treating a

disease that already exists.”

Developing better ways of treating and preventing kidney diseaseEvery year, diabetes costs Louisiana an

estimated $5.4 billion. Of course, the human

costs are much higher.

Diabetes increases the risk of developing serious

health problems including blindness, stroke,

nerve damage, foot issues, skin infection, severe

intestinal problems and kidney disease.

Many of these complications result from

breakdowns in the body’s metabolic processes,

the biochemical reactions that occur within

cells to maintain life.

One damaging cellular imbalance involves

reactive molecules running amuck as they

prevent birth defects, such as spina bifida.”

The ddPCR instrument accurately measures

how those genetic activities differ in diabetic

and normal pregnancies. “It is that new level of

precision that will help move our experiments

forward in a significant way,” he says.

“What we hope to do is find ways to prevent

those birth defects in diabetic pregnancies and

make life easier for those families,” he says.

Combating the obesity that contributes to chronic diseaseNearly one in three Louisianians is obese—

meaning their weight far exceeds the healthy

range for their height.

People who are obese are at increased risk for

premature death and a host of other health

problems including high blood pressure, stroke,

gallbladder disease, heart disease, some cancers,

osteoarthritis and even mental illness.

Decreasing obesity in our population is

essential to reducing the incidence of chronic

disease and improving citizens’ overall health

and wellbeing.

For a while, scientists have known that

sympathetic nerves play a role in controlling

obesity. Throughout the body, these nerves fire

the signals that travel molecular highways and

converge in the brain. Based on input from

peripheral nerve signals, the brain constantly

makes changes to food intake and energy

expenditure.

However, the relationship between fat tissue

and the peripheral nerve system is largely

unexplored—especially the biochemical

reactions that take place along the pathway.

Associate Professor Heike Muenzberg-

Gruening, Ph.D., in the Leptin Signaling

Laboratory hypothesizes the fibers that run

along those pathways may each have a unique

genetic make-up. Her goal is to label the

function and identify the genetic profile of the

individual ganglia along the spinal column.

To recognize their distinct genetic

characteristics and follow the connections

between the peripheral nerves and the brain,

Muenzberg-Gruening must be able to examine

specimens at the molecular level to identify

microscopic structures within the context of

the larger spinal cord and trace a path.

Traditional microscopes lack that capability.

However, the dissecting fluorescent microscope

increases efficiency and accuracy because it

What we hope to do is find ways to prevent those birth

defects in diabetic pregnancies and make life easier for those

families.

—Dr. J. Michael Salbaum


Dr. Heike Muenzberg-Gruening uses the dissecting fluorescent microscope to examine a nerve pathway.


LEVERAGING PHILANTHROPIC INVESTMENTWhile the dissecting microscope is invaluable in mapping the peripheral nerve pathways, the investment in this piece of highly sophisticated equipment has already reaped tremendous return.

Within a few months of receiving the microscope, Heike Muenzberg-Gruening, Ph.D., received a National Institutes of Health grant for $1.8 million.

Sharing visual data and methodological performance is a big part of this grant. Muenzberg-Gruening built a convincing case. She explained to grant reviewers that this sophisticated equipment allowed her to perform the proposed studies and document every step of the methodological development as proposed.

While Muenzberg-Gruening is the principal investigator, faculty members Hans-Rudi Berthoud, Ph.D.; David Burk, Ph.D.; J. Michael Salbaum, Ph.D.; Sangho Yu, Ph.D.; Jackie Stephens, Ph.D.; Rob Noland, Ph.D.; and, Randy Mynatt, Ph.D., will collaborate on the project.

The NIH grant, made possible by the gift from the Edward G. Schlieder Educational Foundation, illustrates our Foundation’s ability to leverage philanthropic investment.

seek to pair their single electron by stealing

one from another molecule. While the body

can compensate for some of their activity, an

overabundance of these free radicals results in

oxidative stress.

The persistent, heightened oxidative stress

common in both Type 1 and Type 2 diabetes

activates pathways can disrupt insulin

signaling and cause beta cell dysfunction and

insulin resistance. This molecular imbalance

can eventually lead to immune system

dysfunction and even organ failure.

“We know high sugar and high fat leads to these

conditions,” explains Krisztian Stadler, Ph.D.,

associate professor of research in the Oxidative

Stress and Disease Laboratory. “We also

know that even with a well-controlled blood

sugar, people with diabetes have a high risk of

developing these complications.”

So, Stadler seeks to pinpoint the metabolic

processes and chemical composition of

molecules that herald the beginning of cell

deterioration caused by oxidative stress. That

requires the ability to identify and characterize

the molecules that are causing this condition.

The new HPLC separates compounds and

molecules in a mixture and performs a

sophisticated analysis to identify, separate and

characterize these molecules. In doing so, it

tells researchers exactly which molecule appears

in excess.

“So, if we know which one is over produced in

the disease,” Stadler explains, “maybe we can

develop a future novel therapy to target these

molecules.”

And, since oxidative stress plays a role in many

disease processes, Pennington Biomedical’s

research may have implications beyond diabetes

for wound healing and other illnesses that

result from the dissolution of organs and tissue.

The fluorescent dissecting microscope, ddPCR

and HPLC have been at Pennington Biomedical

for only a few months. Yet, they have already

enhanced the research of several principal

investigators.

As other faculty begin to take advantage of

the equipment’s capabilities, new and creative

applications of the technology will continue to

emerge for many years to come. •

If we know which one is over produced…maybe we can

develop a future novel therapy to target these molecules.

—Dr. Krisztian Stadler


Peggy M. Pennington Cole Endowed Chair in Maternal Biology and the Risk of Obesity Donor: Irene W. and C.B. Pennington Foundation and the Community Foundation for Southeastern Michigan Eminent Scholar: Claudia Kappen, Dr. rer. nat.

John S. McIlhenny Endowed Chair in Health Wisdom Donor: Coypu Foundation Trust Eminent Scholar: Under Recruitment

John W. Barton, Sr. Endowed Chair in Genetics and Nutrition Donor: Various Eminent Scholar: Claude Bouchard, Ph.D.

Fairfax Foster Bailey Endowed Chair in Heart Disease Prevention Donor: Laura and James J. Bailey III, Virginia and John Noland, P. Foster Bailey Eminent Scholar: Kishore Gadde, M.D.

ENDOWED PROFESSORSHIPSDouglas L. Manship, Sr. Endowed Professorship in Diabetes Donor: Douglas L. Manship, Sr. Eminent Scholar: Randall Mynatt, Ph.D.

John Stauffer McIlhenny Endowed Professorship in Nutrition Donor: Coypu Foundation Trust Eminent Scholar: Phillip Brantley, Ph.D.

George H. Bray Professorship Donor: Various Eminent Scholar: Hans-Rudolph Berthoud, Ph.D.

John S. McIlhenny Professorship in Nutritional Neuroscience Donor: Coypu Foundation Trust Eminent Scholar: Richard Rogers, Ph.D.

John Henry Hernandez Professorship in Health Promotion Donor: Coypu Foundation Trust Eminent Scholar: Thomas Gettys, Ph.D.

Dudley and Beverly Coates Endowed Professorship Donors: Catherine Coates, Camille Coates, Holly Coates CarvilleEminent Scholar: Tiffany Stewart, Ph.D.

$16.7 MILLION VALUE OF ENDOWMENTS

AS OF JUNE 30, 2016Since inception, these endowments

have generated over $9 million in support to Pennington Biomedical

Research Center.

Pennington Biomedical Research Foundation is continually working to secure private funding for endowed chairs, professorships and fellowships. Derived from a Louisiana constitutional amendment in 1984, the Louisiana Education Quality Support Fund and the Louisiana Educational Quality Trust Fund provide state matching funds for endowed chairs, professorships and fellowships. Established by the Louisiana Board of Regents, the Eminent Scholars Program establishes a permanent endowment beginning with $1 million, and the Endowed Professorship program establishes a permanent endowment beginning with $100,000. These endowments are created by private contributions to the Foundation that equal 60% of the endowment matched by 40% from the Board of Regents. The importance of this program is twofold. First, it increases the total impact of funding necessary to conduct the research and educational programs of the Pennington Biomedical Research Center. Second, donors are given the opportunity and the benefit of multiplying their donations by taking advantage of matching rules and regulations. Consequently, they are able to create a much larger endowment to benefit Pennington Biomedical. These endowments exist in perpetuity, as only a portion of the earnings are spent annually for research expenses and educational programs.

ENDOWED CHAIRS AND FELLOWSHIPS

Claude B. Pennington, Jr. Endowed ChairDonor: C.B. “Doc” Pennington Eminent Scholar: Jacqueline Stephens, Ph.D.

United Companies / Harris J. Chustz Endowed Chair Donor: United Companies Eminent Scholar: Abba Kastin, M.D., Ph.D.

Hibernia National Bank / Edward G. Schlieder Endowed Chair Donor: Edward G. Schlieder Educational Foundation and Capital One, formerly Hibernia National Bank Eminent Scholar: Jeffrey Keller, Ph.D.

George A. Bray, Jr. Endowed Super Chair in Nutrition Donor: Pennington Medical Foundation Eminent Scholar: William T. Cefalu, M.D.

Douglas L. Gordon Endowed Chair in Diabetes and Metabolism Donor: Edward G. Schlieder Educational Foundation Eminent Scholar: Eric Ravussin, Ph.D.

LPFA Endowed Fellowship Donor: Louisiana Public Facilities Authority Eminent Scholar: Leanne Redman, M.S., Ph.D.

Marie Edana Corcoran Endowed Chair in Pediatric Obesity and Diabetes Donor: Our Lady of the Lake Foundation Eminent Scholar: Peter Katzmarzyk, Ph.D.

ENDOWMENTS FOR SCIENCE


James A. “Jim” RaglandG. Randolph “Randy” Rice, Ph.D.Ragan RichardRandy RousselJulia H. ThorntonJohn G. TurnerMonica L. Zumo

THE ANSWER COMMITTEEJohn and Marty Engquist, Co-chairs Annette D. Barton Catherine Childers Paula Pennington de la Bretonne Anne T. Duke Claire Engquist Blaine Grimes Beverly Heymsfield Donna Jolly Shannon Poche’ Margaret F. Read Mandy Shipp Buddy Tucker

2016 EMPLOYEE GIVING CAMPAIGN CO-CHAIRSJason Collier, Ph.D. Anne T. Duke Amanda Staiano, Ph.D.

PENNINGTON BIOMEDICAL RESEARCH FOUNDATION BOARD OF DIRECTORS

OfficersJ. Gerard “Jerry” Jolly, Chairman Tim Barfield, Immediate Past-Chair C. Kris Kirkpatrick, Vice-Chair C. Brent McCoy, Treasurer Annette D. Barton, Secretary

DirectorsJ. S. “Si” Brown III Maxine Cormier Paula Pennington de la Bretonne Art Favre Michael Fleming, M.D. John A. Graves Leroy Harvey Charles W. Lamar III Charles A. Landry Richard A. Lipsey Carl S. Luikart, M.D. James R. McIlwain George D. Nelson, Jr. John B. Noland, Sr. Janet L. Olson Claude B. Pennington III Daryl B. Pennington, Sr. Nicolas Perkin William B. Richardson, Ph.D. Christel C. Slaughter, Ph.D. John M. Spain Leonard J. Sullivan Julia H. Thornton John G. Turner Karen R. Williams, M.D. Monica L. Zumo

Ex Officio MembersF. King Alexander, Ph.D. William T. Cefalu, M.D. The Honorable Melvin “Kip” L. Holden Brad Jewell Adam L. KnappJake L. Netterville Cheryl Olinde Joseph B. “Beau” Olinde, Jr. William L. Silvia, Jr.

2015-2016 ANNUAL FUND FOR EXCELLENCE Cheryl and Joseph B. “Beau” Olinde, Co-ChairsThomas Brown IIIOwen CopeJohn S. Coulter*Louis D. CuretBrent GarrettJeffrey E. GouldFran HarveyLeroy HarveyMark W. HerbstLou HudsonJay LittleDonna JollyJ. Gerard “Jerry” JollyAnn Reiley JonesVicki P. KellumC. Kris KirkpatrickScott KirkpatrickE. Lansing KolbC. Stokes McConnell, Jr.James R. McIlwainCamm MortonRussell MoselyLinton J. Naquin, Jr.George D. Nelson, Jr.Patty A. NewtonJanet L. OlsonO. William “Bill” O’QuinKevin M. PattonJames A. “Jim” Poche’ III

VOLUNTEER LEADERSHIP

* Deceased


PHILANTHROPIST $50,000 and above Patsy and Lawrence D. AdcockAmylin Pharmaceuticals, Inc.Laura and James J. Bailey IIIThe John W. Barton Family FoundationDr. Claude Bouchard and Monique ChagnonNan and Herb BoydstunMitzi and George A. Bray, M.D.Imo N. Brown Memorial FundMary Kay and J. Terrell BrownCenters for Obesity Research & EducationCIGNA FoundationColumbia Medical Center of Baton RougeJenny Craig Management, Inc.Lev DawsonThe Dow Chemical CompanyGuaranty CorporationJohn and Cynthia GravesH&E Equipment ServicesMargaret C. Womack HartMr. and Mrs. John H. HernandezJerry and Donna JollyD. Benjamin KleinpeterCharles and Josephine Lamar Memorial Fund Mr. and Mrs. Bill Dixon Mr. and Mrs. Charles W. Lamar IIISusan and Richard LipseyLouisiana Ballooning FoundationLouisiana CAT, LLC Clark G. Boyce Robert M. Boyce Robert D. Webb*Douglas L. Manship, Sr.Mars, IncorporatedAnonymousNanette NolandNutrition 21, Inc.Anonymous Performance Contractors, Inc. / Art E. FavrePhenex Pharmaceuticals AGPhytomedics, Inc.Placid Refining Company, LLC

*Norma Jean RaifordRoche Laboratories, Inc.Donna H. Ryan, M.D., and Edwin LupbergerAnonymousChuck and *Jerry SchwingHovey S. Simon - Uniroyal Chemical Company FundSlim Fast Foods CompanyThe Josef Sternberg Memorial FundMr. and *Mrs. Leonard J. SullivanMoo and Martin SvendsonTakeda Pharmaceuticals North America, Inc.Roland and Kay ToupsTurner Industries Group, LLCCharlie and Nancy ValluzzoThe Milford Wampold Support FoundationWestlake PartnersWHLC ArchitectureMargaret C. and *Milton J. WomackWoman’s Hospital

PARTNER $25,000 and above The AdvocateAgritech Company, Inc.AjinomotoAll Star Automotive GroupAllen & Gooch, A Law CorporationAmerican Medical Association - Educational Research FoundationAnonymousB R & R FoundationBaton Rouge Coca-ColaBrenda and Lee Michael Berg *Jeanelle BeskinJeanie and David BondyH. Douglas Braymer, Ph.D. Marilyn BraymerBuquet & LeBlanc, Inc.Campus Federal Credit UnionCommunity Coffee CompanyMaxine Cormier*Louis D. Curet

PENNINGTON SOCIETY $1,000,000 and above *C.B. “Doc” and *Irene W. PenningtonBaton Rouge Area Foundation*Imogene N. Brown in memory of L. Heidel BrownCommunity Foundation for Southeastern MichiganCoypu Foundation TrustEdward G. Schlieder Educational FoundationIrene W. and C.B. Pennington FoundationLouisiana Public Facilities AuthorityVirginia B. and John B. NolandOur Lady of the Lake FoundationPennington Medical FoundationJohn G. Turner and Jerry G. Fischer

PRESIDENT’S CIRCLE $500,000 and above Bailey and Noland Families Laura and James J. Bailey III Virginia B. and John B. Noland P. Foster Bailey**John W. Barton, Sr.Capital One (formerly Hibernia National Bank)The Coca-Cola CompanyEntergy Alta and John Franks FoundationJPMorgan Chase Bank (formerly Bank One, City National Bank, Premier Bank and LNB)The Charles Lamar FamilyThe Reilly Family FoundationUnited Companies Financial Corporation / Harris J. Chustz

PREEMINENT BENEFACTOR $250,000 and aboveAnnette D. BartonBlue Cross and Blue Shield of Louisiana*Dr. William Hansel

Lamar AdvertisingDon and Pat LyleSue and *Bert Turner

PREMIER BENEFACTOR $100,000 and above Albemarle FoundationAmedisys, Inc.Tim and Nan BarfieldBaton Rouge General Medical CenterMr. and Mrs. Dudley W. CoatesThe Children of Dudley and Beverly Coates in honor of their father Camille Coates Catherine H. Coates Holly Coates CarvilleDr. Jacques and Paula Pennington de la BretonneGordon & Mary Cain FoundationLoretta M. and *Edward M. DowneyEli Lilly and CompanyExxonMobilAnonymous Bill and Anne HiseHelen and Ben JohnsonKnoll Pharmaceutical - BASF CorporationDr. Iris KruppMr. and Mrs. Charles W. Lamar IIILouisiana Charities TrustKevin R. Lyle*Ruth and *Charles W. McCoyRobert W. Merrick*Margaret C. MooreOur Lady of the Lake Regional Medical CenterGary and Claudia PhillipsMr. and Mrs. Kevin P. Reilly, Jr.RoyOMartinUnited Way of Southeast LouisianaWhitney Bank

HONORING LIFETIME GIVING

* Deceased * Deceased


Corporate Management of Baton Rouge, Inc.Grady CrawfordCrompion InternationalThe Crow FoundationJean H. Curet Fund for Medical ResearchDonna and Benjamin DiChiaraAglonie and Michael S. DiVincenti, Jr.Edgen Murray Corporation*Kathryn and David M. Ellison, Jr.Ms. Stephanie FerryCharles and Pam FisherMs. Lynnette B. FrazerGlaxoSmithKline*Patricia and *Robert S. Greer, Sr.The Boo Grigsby FoundationHealth and Nutrition Technology, Inc.Dr. and Mrs. Steven B. HeymsfieldMr. and Mrs. John Hill, Jr.Richard and Debra HiseiHeartMedia, Inc. (formerly Clear Channel Communications)Donald and Kitty IngramInvestar BankJ. B. James ConstructionDr. and Mrs. Sheldon A. JohnsonJones WalkerAnn Reiley JonesMargo and Roy G. Kadair, M.D.Gretchen and Lee KantrowDrs. Jeffrey and Annadora KellerJane and Kris KirkpatrickKnobloch, Poche, Burns Wealth Management GroupLafayette General Medical CenterAnonymous *Mrs. W. H. “Bill” LeBlancThe Alma Lee and H. N. Saurage, Jr. FundAnne and Walter LegettMr. and Mrs. Abraham C. LittenbergMr. and Mrs. Jay LittleLouisiana CompaniesLouisiana Diabetes Foundation, Favre & Lipe Research FundLouisiana Public Health Institute

Anonymous Jonathan and Maggie MartinDr. and Mrs. Roy J. MartinMary Bird Perkins Cancer Center*John S. McIlhennyJim and Terri McIlwainPriss and *Robert H. McNeese, Sr.McNeil NutritionalsMerrill LynchHenry K. and Penny S. MillerMiss Teen USA - Miss Universe OrganizationWilliam T. Montau Charitable TrustJulie and Leonard R. Nachman IINational Dairy CouncilNational Physical Activity Plan Alliance Neothetics, Inc.Mr. and Mrs. Jake L. NettervilleNew Country 100.7 The TigerMr. James M. NolanNorth American Association for the Study of ObesityNovo Nordisk, Inc.Olinde’s FurnitureMr. and Mrs. Thomas OlindeJanet L. OlsonGail and Bill O’QuinPamlab, LLCDr. Ruth M. PatrickMr. and Mrs. Claude B. Pennington IIIMr. and Mrs. Daryl B. Pennington, Sr.PepsiCo, Inc.Phyllis Perron and AssociatesThe Bill Peters FamilyMary Olive PiersonPost ArchitectsBryan and Raymond G. Post, Jr.Mrs. Gretchen P. PressburgMr. and Mrs. Thomas M. RandolphRCF Investment Partnership, LLCREMS GroupDr. Richard C. Rogers and Dr. Gerlinda HermannAnonymousDr. Jennifer C. Rood and Mr. Michael Rood

Digestive Health Foundation of LouisianaSylvia and Gene DukeEquitas Capital Advisors, LLCArthur J. Gallagher and Co.The John Galt FundTodd and Gwen Graves Anonymous Barrie and Lee GriffinFran and Leroy HarveyCordell and Ava HaymonSteve Hicks/Provident Resources Group, Inc.Ingredion, Inc.Kellogg CompanyLuther and Kathryn KissamKPMG, LLPKraft Foods North America, Inc.Latter & Blum, Inc. / C.J. Brown RealtorsGordon and Teri LeBlancC.C. and Alex Lewis FamilyLong Law Firm, LLPBrent and Sunny McCoyLee and Phyllis McLaurinMcMains FoundationMerck & Company, Inc.Milton J. Womack, Inc.Noesis Data, LLCNutrition Science InitiativeOrentreich Foundation for the Advancement of ScienceJoanie and Allen PennimanThe Perkin FundThe Pew Charitable TrustsPfizer, Inc.Postlethwaite & Netterville, APACRaising Cane’s Chicken FingersJennifer and Sean Reilly The Shaw Group, Inc.Page and William L. Silvia, Jr.ST&T International, Inc.Teva Neuroscience, Inc.The Newton B. Thomas Family / Newtron Group FundTomarlee FoundationSari and Thomas Turner

WBRZ-TV Channel 2WellCare Health ServicesW.R. Grace & CompanyJennifer and Chuck WinsteadJoanna Wurtele

PATRON $10,000 and above AnonymousAnne and Herschel AbbottABIC International ConsultantsAdams and Reese, LLPAmerica on the MoveAmgen, Inc.Associated Food StoresPrinceton and Dadie BardwellPeggy and John Barton, Jr. Baton Rouge Cardiology CenterBayou Radiation Oncology Inc. Dr. Andy Lauve and Dr. William E. RussellDr. Drake E. BellangerBernhard Brothers Mechanical Contractors, LLCDr. Hans-Rudolf BerthoudBlue Cross and Blue Shield of Louisiana FoundationHannis T. Bourgeois, LLP, CPAs*Mrs. Jane T. BoycePhil and Paula BrantleyBreazeale, Sachse & Wilson, LLPBREC FoundationBruce Foods CorporationBusiness First BankMr. and Mrs. J.H. Campbell, Jr.Drs. Laura and William M. CassidyWilliam and Elizabeth CefaluCatherine Champagne, R.D., Ph.D.Chef Don Bergeron EnterprisesThe Children’s HospitalCitizens Bank & TrustCity Social MagazineClick Here Publishing



Dr. and Mrs. Michael FlemingDr. Elizabeth Floyd and Steven BarkerFourrier Agency, Inc.Anonymous Freeport McMoRan FoundationMary Barrett FruehanGalatoire’s BistroGeneral MillsGMFS, LLCBob Greer Family*Ann Harrison Parnell GregorieIsaac M. Gregorie, Jr.Robert T. Grissom, M.D.Anonymous Liz HamptonAnonymousDr. and Mrs. Richard M. HillWilliam R. HolmanIBERIABANKinforMD Solutions, LLCInvitrogen CorporationDr. Anne Rossi JarrettChristy and Brad JewellJohnson Riley and Associates, LLCDr. and Mrs. William D. JohnsonKean Miller LLPKraft Foods, Inc.Land O’Lakes Purina FeedIsabel and Clifton C. Lasseigne, Jr.Dr. and Mrs. W. Joseph Laughlin, Jr.Launch MediaLEMIC Insurance CompanyMr. and Mrs. W. Conville LemoineLevel HomesJ. B. Levert Foundation, Inc.Mr. and Mrs. Robert B. LevyLipsey’s Richard Lipsey and Laurie Aronson Lofton Staffing & Security ServicesLyons Specialty Co., LLCNat and Lynda Maestri*Mrs. Paula Garvey ManshipMary Beth and Michael H. MartinMartin Wine Cellar

Matherne’s SupermarketMr. and Mrs. James E. MaurinMary Jo MayfieldKathy and Frank McArthurStokes and Noy McConnellMcCormick & Company, Inc.McDonald’s of Baton RougeSue and Ed MiddletonJohn and Jane MilazzoMr. Daniel MiremontMorgan Keegan and Company, Inc.Morgan Stanley*Hermann Moyse, Jr.Moyse Family Foundation*Carolyn and D. Denis MurrellMark D. MurrellMr. and Mrs. George D. Nelson, Jr.Nestle’ S.A.Northshore Community FoundationMr. William P. Obier, Jr.Mr. and Mrs. Gene E. Ohmstede, Jr.Anonymous Dan and Kathleen O’LearyOrexigen Therapeutics, Inc.Mr. and Mrs. James W. Parks IIJudie and Kirk. A. Patrick, Jr.The Peanut InstitutePeoples Health NetworkPetrin CorporationPhelps Dunbar, LLPMike and Heather PittsJim and Shannon Poche’Pregnant Ideas Inc./DBA Metabolic Testing Services Proctor & Gamble CompanyMr. and Mrs. Louis S. Quinn, Jr.Sue and *Bob RainerRenal Associates of Baton Rouge, LLCRagan and Virginia RichardRickey Heroman’s Florist & GiftsNancy and Floyd Roberts, Jr.Al and Anne RotenbergAyan and Mike RubinBeverly and Rory Russell

* Deceased

Frank and Janice SadlerElizabeth SammonsServier AmeriqueSeven Holdings, LLCJohn F. and *Helen SieberthFrank and Marcy Simoneaux*Mr. and Mrs. Joe D. SmithSteven R. Smith, M. D., and Joffa Braymer, M.D.Source Capital, LLCSoutheastern Cardiovascular Consultants, LLCSt. James PlaceHans and Donna SternbergTaylor Porter Law Firm*Ida and *J. Frank Terrell, Jr.*Charlotte M. ThompsonBonnie Hymel Trentacoste and Sal TrentacosteMalcolm L. TuckerU.S. Army Research Institute of Environmental MedicineUniversity Club PlantationUSDAWhole Foods Market, Inc.Ann WilkinsonWillis-Knighton Health SystemDavid and Anne Winkler*Barbara Womack*Mr. and *Mrs. William H. Wright, Jr.Bobby and Marsha Yarborough

PACESETTER $5,000 and above Mr. and Mrs. Thomas J. AdamekDr. and Mrs. Charles E. AfemanAirtrol, Inc.Allrite Electric, Inc.American Association of Clinical EndocrinologistsAmerigroup LouisianaAnalytic StressDr. Mary Lou ApplewhiteArthritis FoundationMr. and Mrs. George A. Atherton

Mr. and Mrs. Dennis AucoinBancorpSouth Insurance Services / Wright & PercyMr. Bradley W. BarberMary Scott BartonDr. and Mrs. B. Eugene BerryDr. and Mrs. Frederic T. Billings IIIMr. and Mrs. Herbert J. BoxillMelanie and John BoyceRobert and Julia BoyceBRECMr. and Mrs. Claude T. Bromley IIIMr. and Mrs. J. S. “Si” Brown IIICajun Industries, LLCDaniel T. Calongne and Associates*Mrs. Ruth S. CalhounRosemary and *John S. Campbell, Jr.Capital Valve & Fitting Co., LLCCatalyst Pharmaceutical Partners, Inc.Patricia L. CheramieDr. and Mrs. Timothy S. ChurchCintas CorporationCity of Baton Rouge/ Parish of East Baton RougeColon Cancer CoalitionCommunity Health Charities of LA and MSCovidienCrestar Financial Corporation*George A. DanielsDr. and Mrs. Dave DavisdeGravelles & AssociatesMr. Michael T. DelahayeDr. and Mrs. Robert L. DelarosaJuliet S. DoughertyAnne T. and Stuart W. DukeElder Outreach of Louisiana, Inc.*Mrs. Eleanor J. EldredgeMr. and Mrs. Jim EppersonEthicon Endo-Surgery, Inc.John M. and Diane EvansJohn and Glynda FetzerFidelity Charitable Gift FundSharon and *Jack FieldFishman Haygood, LLP

* Deceased


Matthew McKay / All Star Automotive Group Alta and John Franks Foundation Amedisys, Inc. Laura and James J. Bailey III Tim and Nan Barfield Annette D. Barton The John W. Barton Family Foundation Baton Rouge Area Foundation Baton Rouge General Medical Center Dr. William Russell and Dr. Andy Lauve / Bayou Radiation Oncology Inc. Brenda and Lee Michael Berg Blue Cross and Blue Shield of Louisiana Dr. Claude Bouchard and Monique Chagnon Clark G. Boyce Robert M. Boyce Capital One Camille Coates Catherine CoatesHolly Coates Carville Mr. and Mrs. Dudley W. Coates The Coca-Cola Company Coypu Foundation Trust Dr. Jacques and Paula Pennington de la Bretonne Edward G. Schlieder Educational Foundation John and Marty Engquist Equitas Capital Advisors, LLC John and Cynthia Graves Todd and Gwen Graves / Raising Cane’s H&E Equipment Services *Dr. William Hansel Fran and Leroy Harvey Bill and Anne Hise Irene W. and C.B. Pennington Foundation Helen and Ben Johnson Jerry and Donna Jolly Dr. Iris Krupp Lamar Advertising

Mr. and Mrs. Charles W. Lamar III Susan and Richard Lipsey Mr. and Mrs. Abraham C. Littenberg Louisiana Charities Trust Louisiana Public Facilities Authority Don and Pat Lyle Kevin R. Lyle RoyOMartin Robert W. Merrick Anonymous Virginia B. and John B. Noland Our Lady of the Lake Foundation Mr. and Mrs. Claude B. Pennington III Mr. and Mrs. Daryl B. Pennington, Sr. Art Favre / Performance Contractors, Inc. Nanette Noland / The Powell Group Gretchen P. Pressburg The Reilly Family Foundation Mr. and Mrs. Kevin P. Reilly, Jr. Jennifer and Sean Reilly Anonymous Mary Ann Sternberg Mr. Leonard J. Sullivan Moo and Martin SvendsonRoland and Kay Toups John G. Turner and Jerry G. Fischer Sue Turner Charlie and Nancy Valluzzo Robert D. Webb WHLC Architecture

COUNCIL OF 100

Pennington Biomedical Research Foundation established the Council of 100 for individuals, foundations and businesses who give $10,000 or more in annual support or who have made gifts of $100,000 or more and remain actively involved with Pennington Biomedical.

* Deceased

LEGACY SOCIETY

Legacy Society members are individuals who have made a planned gift to Pennington Biomedical Research Foundation or have notified the Foundation of their intention to do so. Members of the Legacy Society are dedicated to supporting Pennington Biomedical’s mission for generations to come.

Annette D. Barton Dr. Claude Bouchard and Monique Chagnon *Jane T. Boyce H. Douglas Braymer, Ph.D. Marilyn Braymer Catherine Champagne, R.D., Ph.D. Mr. and Mrs. Dudley W. Coates *Dr. William Hansel Jerry and Donna Jolly Beverly Carson Jones Dr. Iris Krupp Kathy and Frank McArthur *Margaret C. Moore Virginia B. and John B. Noland Gretchen P. Pressburg *Norma Jean Raiford Dr. Jennifer C. Rood and Mr. Michael Rood *Charlotte M. Thompson Ann Wilkinson

Tony and Carol SavoieSchwab Charitable FundAaron or Peggy Selber Foundation, Inc.The Carter Chapman Shreve Family FoundationSierra Research Group, LLCMrs. Joseph S. SimmonsJ. Noland SingletaryChristel C. and William S. Slaughter IIIMr. and Mrs. Lee Solomon, Solomon Family FoundationMr. and Mrs. John M. SpainGabriella and Marshall St. AmantStar Service, Inc.Stuart & Company General Contractors, LLCJohn and Martha StinsonElizabeth SpauldingRalph and Margi UnderwoodUnilever Corporate ResearchMs. Judith VitanzaV-Tones, LLCWAFB-TV Channel 9Mrs. Nancy WalterWampold CompaniesWeight Watchers International, Inc.WF Communications, LLCJanet and John A. YoungMonica and Tony Zumo

* Deceased


The Powell GroupJennifer and Sean Reilly FamilyMr. and Mrs. Kevin P. Reilly, Jr.The Josef Sternberg Memorial FundLeonard J. SullivanTomarlee FoundationCharlie and Nancy ValluzzoWHLC Architecture

$5,000 - $9,999Mr. Bradley W. BarberDr. Hans-Rudolf BerthoudBlue Cross and Blue Shield of LouisianaBlue Cross and Blue Shield of Louisiana FoundationCampus Federal Credit UnionThe Carter Chapman Shreve Family FoundationEntergy CorporationCordell and Ava HaymonHealth and Nutrition Technology, Inc.JPMorgan Chase BankGordon and Teri LeBlancLevel HomesLouisiana Public Facilities AuthorityLee and Phyllis McLaurinMerck & Company, Inc.Our Lady of the Lake Regional Medical CenterMr. and Mrs. Thomas M. RandolphChuck SchwingPage and William L. Silvia, Jr.The Newton B. Thomas Family / Newtron Group Fund

$2,500 - $4,999B-C Equipment SalesDr. and Mrs. B. Eugene BerryPhil and Paula BrantleyMitzi and George A. Bray, M.D.William and Elizabeth CefaluDr. and Mrs. Robert L. DelarosaDonna and Benjamin DiChiara

Fishman Haygood, LLPDr. and Mrs. Michael FlemingFourrier Agency, Inc.Mr. and Mrs. Todd A. GeraldGMFS, LLCHannis T. Bourgeois, LLP, CPAsMr. and Mrs. John H. HernandezDr. and Mrs. Steven B. HeymsfieldMr. and Mrs. John Hill, Jr.Ann Reiley JonesJane and Kris KirkpatrickKnobloch, Poche, Burns Wealth Management GroupKPMG, LLPLCTA Workers’ CompBrent and Sunny McCoyHenry K. and Penny S. MillerNFP Benefits Solution Group, Inc.Anonymous Dan and Kathleen O’LearyMr. Hays D. OwenPeoples Health NetworkMary Olive PiersonPostlethwaite & Netterville, APACKristy Roubique AnonymousMr. Kelly C. SillsUniversity Club PlantationV-Tones, LLCMilton J. Womack, Inc.

$1,000 - $2,499Mr. and Mrs. Thomas J. AdamekAdvanced Sealing InternationalDr. and Mrs. Charles E. AfemanAirtrol, Inc.Allrite Electric, Inc.Dr. Mary Lou ApplewhitePris and Eddie AshworthPrinceton and Dadie BardwellBeau Box Property ManagementPeggy and John Barton, Jr.Dr. and Mrs. Charles D. Belleau

DISCOVERY PARTNERS $100,000+Baton Rouge Area FoundationDr. Jacques and Paula Pennington de la BretonneEdward G. Schlieder Educational FoundationIrene W. and C.B. Pennington Foundation

$50,000 - $99,999Annette D. BartonVirginia B. and John B. NolandJohn G. Turner and Jerry G. FischerSue Turner

$25,000 - $49,999Baton Rouge General Medical CenterCapital OneH&E Equipment ServicesPerformance Contractors, Inc. / Art E. FavreRaising Cane’s Chicken Fingers and the Graves FamilyST&T International, Inc.Takeda Pharmaceuticals North America, Inc.

$10,000 - $24,999All Star Automotive Group/Matt McKayTim and Nan BarfieldThe John W. Barton Family Foundation

Bayou Radiation Oncology Inc. / Dr. Andy Lauve and Dr. William E. RussellBrenda and Lee Michael BergDr. Claude Bouchard and Monique ChagnonMr. and Mrs. Dudley W. CoatesEquitas Capital Advisors, LLCJohn and Cynthia GravesFran and Leroy HarveyBill and Anne HiseAnonymous Jerry and Donna JollyMr. and Mrs. Charles W. Lamar IIILamar Advertising Susan and Richard LipseyC.C. and Alex Lewis FamilyMr. and Mrs. Abraham C. LittenbergLouisiana CAT Clark G. Boyce Robert M. Boyce Robert D. WebbDon and Pat LyleKevin R. LyleRoyOMartinNational Physical Activity Plan AllianceNeothetics, Inc.Anonymous Nanette NolandVirginia B. and John B. NolandMr. and Mrs. Claude B. Pennington IIIMr. and Mrs. Daryl B. Pennington, Sr.

Philanthropic support is vital to Pennington Biomedical’s scientific progress, and it is the true lifeblood of research. Annual giving, both unrestricted gifts and those restricted to specific research areas, makes an impact.

With your investment, we continue to assemble the brightest and most dedicated scientists and give them the resources they need to improve human health.

Your unrestricted annual gifts are rapidly deployed to fuel pilot research projects, support the best scientific minds and advance frontiers in new technology and enterprise.

ANNUAL GIVING



PENNINGTON BIOMEDICAL RESEARCH

FOUNDATION STAFFWilliam L. Silvia, Jr.

President and CEO

Brad JewellVice President/Chief Financial Officer and

Chief Administrative Officer

K. Jean AhweshVice President of Development

Ann WilkinsonSenior Development Officer

Laurie AllenDirector of Development

Jennifer L. BroadwellDirector of Advancement Services

Tammy DearieExecutive Assistant to the President and CEO

Marci GainesAssociate Director of Development

Adrian E. HirschDirector of Outreach

Tessa MahlerAccountant

Kelly PhillpottDevelopment Coordinator

Dr. and Mrs. Frederic T. Billings IIIMr. and Mrs. Barry O. BlumbergMarvin and Susan BorgmeyerMr. and Mrs. J. S. “Si” Brown IIIMr. and Mrs. J.H. Campbell, Jr.Capital Valve & Fitting Co., LLCCeltic Media CentreCatherine Champagne, R.D., Ph.D.Cintas CorporationMaxine CormierMr. and Mrs. Gregory J. CotterMr. and Mrs. Tommy D. Cowart*Louis D. CuretMr. and Mrs. Charles D’AgostinoJack and Susan DampfMr. and Mrs. John DelahayeMr. and Mrs. Richard J. DodsonJuliet S. DoughertyCarol M. DreherElite Concierge & Rental LLCMr. and Mrs. Jim EppersonAnonymousBarrie and Lee GriffinRobert T. Grissom, MDMr. David HerzogBonnie Hymel Trentacoste and Sal TrentacosteMr. and Mrs. Craig S. JenningsHelen and Ben JohnsonMr. and Mrs. J. Fred JohnsonGretchen and Lee KantrowKantrow, Spaht, Weaver & Blitzer Kean Miller LLP*Ralph and Gail KinneyMr. and Mrs. Scott KirkpatrickMrs. Faye KovichDr. and Mrs. W. Joseph Laughlin, Jr.Anne and Walter LegettJ. B. Levert Foundation, Inc.Lofton Staffing & Security ServicesMr. Donald J. LoganLong Law Firm, LLPLouisiana CompaniesLyons Specialty Co., LLCMr. and Mrs. David Mahler, Jr.

Mary Jo MayfieldKathy and Frank McArthurStokes and Noy McConnellJim and Terri McIlwainMr. Dalton J. MeauxMr. and Mrs. Ellis A. MichaelEdward and Susan MorrisonMoyse Family FoundationMark D. MurrellJulie and Leonard R. Nachman IIMr. and Mrs. George D. Nelson, Jr.Mr. and Mrs. Jake L. NettervilleNoesis DataMr. and Mrs. Gene E. Ohmstede, Jr.Beau and Cheryl OlindeJanet L. OlsonGail and Bill O’QuinMr. Brandon G. ParlangeDr. and Mrs. Earl V. Patterson IIIJulie B. PayerMr. and Mrs. Nicolas PerkinPhyllis Perron and AssociatesThe Bill Peters FamilyPhelps Dunbar, LLPMr. and Mrs. Donald T. PhelpsMs. Stephanie PitreJim and Shannon Poche’Bryan and Raymond G. Post, Jr.Provost Salter Harper & Alford, LLCREMS GroupMargaret and Randy RiceDr. Richard C. Rogers and Dr. Gerlinda HermannTony and Carol SavoieRagan and Virginia RichardNancy and Floyd Roberts, Jr.Dr. Jennifer C. Rood and Mr. Michael RoodAl and Anne RotenbergAyan and Mike RubinDonna H. Ryan, M.D., and Edwin LupbergerDr. J. Michael SalbaumHank and Laurie SaurageAaron or Peggy Selber Foundation, Inc.Shell Oil Company Foundation

The recognition for annual giving reflects gifts received July 1, 2015 through June 30, 2016. If we made an error or omission of your annual or lifetime giving, we apologize and request that you notify us so that we can correct our records.

Mr. and Mrs. John M. SpainSSA Consultants, Inc.Starmount Life Insurance CompanyMr. and Mrs. John H. StinsonTable Kitchen and BarJohn and Martha StinsonMs. Julia H. ThorntonVanguard CharitableWhitney BankAnn WilkinsonKaren Williams and Cornelius LewisJennifer and Chuck WinsteadJanet and John A. YoungMonica and Tony Zumo


Brad and Rachel Barber (from left), Marty and John Engquist and Scott and Clacy Madison at The Answer’s 2016 Bronco Busters & Bunnies gala.

Fishman Haygood, LLPFourrier Agency, Inc.GMFS, LLCKnobloch, Poche, Burns Wealth Management GroupKPMG, LLPNFP Benefits Solution Group, Inc.Postlethwaite & Netterville, APACRaising Cane’s Chicken FingersJohn G. Turner and Jerry G. FischerUniversity Club PlantationMilton J. Womack, Inc.

IN-KIND DONORSBaton Rouge Beer AgencyB-C Equipment SalesBilly Heroman’sCampus Federal Credit UnionWilliam and Elizabeth CefaluCeltic Media CentreMarty J. ChabertChef Don Bergeron EnterprisesCintas CorporationCustom LinensDrybarElite Concierge & Rental LLC

Mignon Faget, Ltd.FS Williams OutfittersJuban’s Restaurant, Inc.Kendra Scott Design, Inc.LA Lobster’sLance Hayes FlowersHannah Lugibihl Fine ArtLux Salon and SpaMakeup by Courtney NicoleMaxwell’s MarketMGMMovie TavernNimbus Creations LLCPainting and PinotPaper and PrettiesRigsby Frederick Salon & GalleryRoberto’s River Road RestaurantRobert’s Fresh MarketTable Kitchen and BarV-Tones, LLCZAZA Nail BoutiqueZoe’s Kitchen

The triumphant team from JP Morgan Chase Bank hoists The Answer trophy.

Pennington Biomedical leadership team was ready for the research rodeo.

Teams try their hand at steer roping in the final competition.

Every day, world-renowned scientists at LSU’s Pennington Biomedical Research Center are exploring the many questions surrounding the triggers and treatment of dementia, diabetes, obesity and other chronic diseases.

Once a year, local sponsors and their guests come together to discover The Answer. This fundraising event challenges Louisiana’s companies to gather their best and brightest for a fast-and-furious, high-tech trivia game.

No matter which team emerges the victor, having The Answer is a win for our community. Proceeds from the event are invested in research that is taking place right here in Baton Rouge and aims to allow people in our state, our nation and across the globe to live longer, healthier lives.

THE ANSWER 2016

PRESENTERSH&E Equipment ServicesIrene W. and C.B. Pennington Foundation

POWER PLAYERSAnnette Barton and Malcolm TuckerBlue Cross and Blue Shield of LouisianaCampus Federal Credit UnionChef Don Bergeron EnterprisesCoastal BridgeJPMorgan Chase BankLevel HomesLouisiana Public Facilities Authority

THRILL SEEKERSDana and Sam AgnewHannis T. Bourgeois, LLP, CPAsArthur J. Gallagher & Co.Baton Rouge General Medical CenterDr. Claude Bouchard and Dr. Phil Brantley


Phillip J. Brantley, Ph.D.Amy BraymerGail Effler-BraymerH. Douglas Braymer, Ph.D.Jennifer L. BroadwellRicky BrockEllen H. BroussardEvest A. BroussardStephanie Broyles, Ph.D.Annadora Bruce-Keller, Ph.D.Barry J. BuchananAnonymousCassie CassidyCatherine Champagne, R.D., Ph.D.Ji Suk Chang, Ph.D.Linda ChaseElizabeth ChesteenTimothy S. Church, M.D., M.P.H., Ph.D.Jason Collier, Ph.D.Susan Collier, Ph.D.Bridget S. ConnerAnonymousLaura S. DallamStacie DavisTammy K. DearieKara DenstelSheletta G. DonattoGena DoucetAnonymousCarol M. DreherMichelle F. DryAnne T. DukeKenneth Eilertsen, Ph.D.Luis EscobarStephen FletcherElizabeth E. Floyd, Ph.D.Elizabeth FrostGreta FryMarci GainesJennifer GonzalezAnonymousEmily Goodin

Anonymous Melissa N. HarrisSharon Y. HebertJennifer HeckertChelsea A. HendrickGerlinda Hermann, Ph.D.Candace HernandezSteven B. Heymsfield, M.D.Adrian E. HirschHsin H. HsuCathy HueyBonnie HymelJenny L. JacksonBrad JewellLisa JonesStephanie JonesClaudia Kappen, Dr. rer. nat.Abba J. Kastin, M.D.Peter Katzmarzyk, Ph.D.Jeffrey Keller, Ph.D.Leighanne KiggansCynthia A. KlosterAnonymousGuy LaVergneStephen P. LeeWalter E. Legett, Jr.Diane F. LowreyTessa MahlerSusan MancusoKara Marlatt, Ph.D.Corby K. Martin, Ph.D.Allison Paige McCownDavid H. McDougal, Ph.D.Marleny MercedesEmily MireRonald B. MonceChristopher Morrison, Ph.D.Vyaisha MossJasper Most, Ph.D.Monica B. MougeotHeike Muenzberg-Gruening, Ph.D.Kori MurrayRandall Mynatt, Ph.D.

Susan NewmanAnonymousStephanie C. NuccioJames R. PalmerLaurel PattersonMelanie PetersonRobin L. PostMonique PowellAlisha PratherTiffany H. PratherEmily Qualls-Creekmore, Ph.D.Tuomo Rankinen, Ph.D.Eric Ravussin, Ph.D.Allison Richard, Ph.D.Brenda K. Richards, Ph.D.Richard C. Rogers, Ph.D.Jennifer C. Rood, Ph.D.J. Michael Salbaum, Ph.D.Mandy ShippWilliam L. Silva, Jr.Kem Singletary, D.V.M.Robert SingletaryLeslie M. SmithJulia St. AmantAmanda Staiano, Ph.D.Lori SteibKirsten Stone, Ph.D.April Stull, R.D., Ph.D.AnonymousValerie ToupsDawn TurnerAnn WilkinsonAubrey WindhamAimee S. YochesSangho Yu, Ph.D.AnonymousMatthew P. Zylicz

PRESENTING SPONSOR

Capital One

The annual Scientific Dinner Series explores cutting-edge research on topics such as disease prevention, exercise and nutrition.

Recent presentations included:

» What Einstein Would Have Said About Pennington Biomedical featuring Claude Bouchard, Ph.D., of Pennington Biomedical Research Center

» Obesity: Facts and Figures featuring guest speaker Samuel Klein, M.D., of Washington University School of Medicine

» Type 1 and Type 2 Diabetes: How Do We Protect the Cells That Make Insulin featuring Jason Collier, Ph.D., of Pennington Biomedical Research Center

2016 IRENE W. PENNINGTON WOMEN’S WELLNESS DAY

PRESENTING SPONSOROur Lady of the Lake Regional Medical Center

CONTRIBUTING SPONSORBlue Cross and Blue Shield of Louisiana

IN-KIND SPONSORSBaton Rouge Cardiology CenterBaton Rouge Coca-Cola Bottling Company

Blue Cross and Blue Shield of Louisiana’s Team BlueCity Social MagazineJason’s DeliMary Bird Perkins-Our Lady of the Lake Cancer CenterNatural Awakenings of Greater Baton RougePeoples HealthValluzzo Family RestaurantsWhole Foods Market, Inc.Woman’s Hospital

EMPLOYEE GIVINGEvery day, the world-renowned researchers at Pennington Biomedical give of their time and talent daily toward a healthier community, state and global community. In addition, Pennington Biomedical employees make philanthropic support a priority. We gratefully acknowledge the contributions of all our staff members. Those employees listed below participated in the 2015-2016 Employee Giving Campaign.

Terry A. AhlertDavid E. AlexanderH. Raymond AllenLaurie AllenAimee AlumbaughCynthia M. AngellozJohn W. Apolzan, Ph.D.AnonymousGrace BellaHans-Rudolf Berthoud, Ph.D.Thomas W. BlalockJerry BlanchardClaude Bouchard, Ph.D.Patti W. Boyd

SCIENTIFIC DINNER SERIES


Dr. Phillip AllenMrs. Laurie Allen

Annette BartonAnn Reiley Jones

*Dr. William HanselRob, Martha, Alison and Amy Rouzer

Mr. and Mrs. John HernandezMelanie and John Boyce

Mr. and Mrs. J. Gerard JollyMr. and Mrs. Frank D. McArthur

Dr. Jennifer and Michael RoodIna M. Carlton

Willis Simmons IIIMs. Lisa Lipsey

Ann WilkinsonAnn Reiley Jones Mr. and Mrs. Frank D. McArthur

TRIBUTES IN MEMORY OF…

Dr. Tomas A. AlveroPurita R. Alvero

Lynn Best BaylesJanet Paris Jeanelle Rekedal BeskinPage and William L. Silvia, Jr. Catherine D. and Harris J. ChampagneCatherine Champagne, R.D., Ph.D.

Dr. Jack D. ClaytonNita K. Harris

George CovertAnnette D. Barton

Louis D. Curet Annette D. Barton Dr. and Mrs. B. Eugene BerryMs. Catherine H. Coates and Dr. Brian HalesMr. and Mrs. Tommy D. Cowart Harlequins Dance Club Mary T. JosephJim and Terri McIlwain Laurie Mullens Margery Olinde Moo and Martin Svendson Ann Wilkinson

Kathryn G. EllisonAnn Reiley Jones Fred Frey, Jr.Mrs. Patricia K. Odom

John Carlyn GaudinKerry DiezJohn Sinquefield and Denise Sinquefield Dr. Douglas L. Gordon, Sr. Nita K. Harris

Betsy HallAnonymous Kit HallAnonymous

Milbrey Hansel Rob, Martha, Alison and Amy Rouzer Dr. Milton L. HarrisNita K. Harris Shelby M. Harris, Jr.George and Anne Kurz

TRIBUTES IN HONOR OF…

* Deceased

Mrs. L. HarrisonChristine Barnard Paul M. Haygood, Jr.Ann Reiley Jones Fred W. HebertThe Lofton Corporation

Fredrick Grant HowardKent A. Howard, Sr.

Cheney C. Joseph, Jr.Mr. and Mrs. James R. Purgerson

Ruby Bosley KingLA O’Connor & Jeremy Dr. Ralph A. KinneyGail Kinney Kenneth C. Landaiche, Sr.Mr. and Mrs. John H. Hernandez

Ms. Marquita McKnightJane and Kris Kirkpatrick Charles J. MittendorfJames M. and Laura H. Field

Trey NaquinMr. and Mrs. Linton J. Naquin, Jr.

Glen and Vera Lee OldsAnonymous

Elsie Mae PerronPhyllis Perron Dr. Charles S. Prosser, Jr.Nita K. Harris

Randy ReaAfter Five Kathy G. ArnesLinda and Brian Babin

John and Nancy BakerThe Szczepkowski FamilyMr. and Mrs. Douglas C. Woolfolk

Melvin and Elaine SchudmakAnn Schudmak Keogh

Helen D. SieberthMcGlinchey Stafford, PLLC The Bill Peters Family

Colonel William M. “Bill” Snow, Jr.Mr. and Mrs. George D. Nelson, Jr.

Barney Cecil “B.C.” Starkey Judy Kerperien

Peggy Ordoyne ToupsDr. Claude Bouchard and Monique Chagnon Catherine Champagne, R.D., Ph.D.

Roland Joseph ToupsDr. Claude Bouchard and Monique Chagnon Catherine Champagne, R.D., Ph.D. Page and William L. Silvia, Jr.

Dr. Clay A. Waggenspack, Jr.Nita K. Harris

Dr. William D. WillisBeverly Carson Jones

Pennington Biomedical Research Foundation62

6400 Perkins Road / Baton Rouge, Louisiana 70808 / 225.763.2511 / fax: 225.763.3108 / pbrf.org

Supporting the Pennington Biomedical Research Center, a campus of Louisiana State University

Documents

2015-2016 STEWARDSHIP REPORT...12 Pennington Biomedical Research Foundation STEWARDSHIP REPORT 2015-2016 13 multi-million dollar grant to establish an NIH center of excellence. For