International Society for Stem Cell Research

The worlds premier stem cell research event

Poster Session Abstracts

June 17 20, 2007Cairns Convention Centre Cairns, Queensland, Australia

Poster Schedule and Poster Floor PlanPoster #: 217 262 Poster #: 198 205 Poster #: 131 190

Poster #: 209 216

Poster #: 191 196

Poster #: 263 278

Poster #: 279 282

Poster #: 125 130 Poster #: 283 296 Poster #: 113 120

Poster #: 121 124

Poster #: 297 372

Poster #: 109 112 Poster #: 381 384 Poster #: 373 380 Poster #: 101 104

Poster #: 105 108

Poster #: 385 386

Main Entrance

Poster SessionsPosters will be presented by authors during the ISSCR Annual Meeting and will be available for viewing each day of the meeting. There will be four separate poster sessions. A complete poster presentation directory is included with your registration materials. Poster sessions are located in Hall 2, Exhibition Level.

Poster Session ScheduleSunday, June 178:00 a.m. 9:00 a.m. 9:00 a.m. 7:30 p.m. 5:30 p.m. 7:30 p.m. 7:30 p.m. Poster Session I Setup Viewing Presentations Dismantle

Tuesday, June 198:00 a.m. 9:00 a.m. 9:00 a.m. 7:30 p.m. 5:15 p.m. 7:00 p.m. 7:00 p.m. Poster Session III Setup Viewing Presentations Dismantle

Monday, June 188:00 a.m. 9:00 a.m. 9:00 a.m. 7:30 p.m. 5:30 p.m. 7:30 p.m. 7:30 p.m. Poster Session II Setup Viewing Presentations Dismantle

Wednesday, June 208:00 a.m. 9:00 a.m. 9:00 a.m. 7:30 p.m. 5:00 p.m. 7:00 p.m. 7:00 p.m. Poster Session IV Setup Viewing Presentations Dismantle

Table of ContentsCANCER STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1SUN - 101: ENDOGENOUS STEM/PROGENITOR CELL AND HOST BRAIN RESPONSES TO HUMAN GLIOMA IN ORTHOTOPIC RODENT MODELS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Najbauer, Joseph, Barish, Michael E., Garcia, Elizabeth, Metz, Marianne Z., Justus, Kristine A., Myers, Sarah M., Gutova, Margarita, Frank, Richard T., Kendall, Stephen E., Glackin, Carlotta A., Bjerkvig, Rolf, Aboody, Karen S. SUN - 102: A HUMAN NEURAL STEM CELL MODEL FOR THE STUDY OF THE PATHOGENESIS OF PAEDIATRIC BRAIN TUMOURS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bertram, Cornelia M., Hawes, Susan M., Peh, Gary S., Egli, Simone, Kees, Ursula R., Dallas, Peter B. SUN - 103: TUMORIGENIC CELLS GENE SIGNATURE OF THE MMTV-WNT-1 MOUSE BREAST TUMOR HAS PROGNOSTIC SIGNIFICANCE TO HUMAN PATIENTS . . . . . . . . . . . . . . . . . . . . . . . 1 Cho, Robert, Diehn, Maximilian, Wang, Xinhao, Clarke, Michael SUN - 104: NOTCH SIGNALLING IN CHRONIC MYELOID LEUKAEMIA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Al-Jedai, Abdullah SUN - 105: ONE-BEAD ONE-COMPOUND FOR IDENTIFYING NOVEL MAMMARY STEM CELL MARKERS . . . . . . . . . . . . . . . . . . 2 Erickson, Kent, Borowsky, Alexander D., Hubbard, Neil E., Damonte, Patrizia, Lam, Kit S. SUN - 106: PROFILING SIDE POPULATION CELLS IN BREAST CANCER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Britton, Kelly, Lennard, T.W.J., Meeson, Annette P. SUN - 107: NG2/HMP PROMOTES CHEMORESISTANCE BY ACTIVATION OF INTEGRIN/PI3K/AKT SIGNALLING AND IS A POTENT THERAPEUTIC TARGET IN VIVO. . . . . . . . . . . . . . . . . . . . . 3 Chekenya, Martha SUN - 108: THE POLYCOMB GENE PRODUCT BMI1 IS ESSENTIAL FOR THE TUMOR-INITIATING CAPACITY OF HEPATOCELLULAR CARCINOMA CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Chiba, Tetsuhiro, Miyagi, Satoru, Iwama, Atsushi SUN - 109: FLOW CYTOMETRY CHARACTERIZATION OF STEM CELL LINEAGES IN THE LIVER OF PATIENTS WITH HEPATIC TUMORS . . 3 Colombo, Federico S., Porretti, Laura, Prati, Daniele, Gramignoli, Roberto, Cattaneo, Alessandra, Lopa, Raffaella, Portararo, Paola, Rossi, Giorgio, Colli, Agostino, Battiston, Carlo, Mazzaferro, Vincenzo SUN - 111: NEDD9 REGULATES EPITHELIAL-MESENCHYMAL TRANSITION IN CANCER STEM CELLS . . . . . . . . . . . . . . . . . . . . . . 3 Francis, Meenal, Pai, Sanjay, Zaveri, Shabber, S. P., Somashekhar, Dadke, Disha S. SUN - 112: CHARACTERIZATION OF NT-ES CELLS DERIVED FROM CLONED EMBRYOS OF MURINE TERATOCARCINOMA CELLS . . . . 4 Fukasawa, Hiroko, Hirata, Shuji, Wakayama, Teruhiko, Hoshi, Kazuhiko SUN - 117: DEPOT-SPECIFICITY OF HUMAN ADIPOSE-TISSUE DERIVED MESENCHYMAL STEM CELLS . . . . . . . . . . . . . . . . . . . . . 5 Choong, Cleo, Hutmacher, Dietmar, Lim, Susan, Soria, Bernat SUN - 118: EFFECTS OF THYMOSIN BETA-4 ON PROLIFERATION AND DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Ho, Jennifer Hui-Chun, Tseng, Kuang-Ching, Kuo, Tom Kwang-Chun, Shih, Vernon Yuru, Su, Yeu, Lee, Oscar Kuang-Sheng SUN - 119: INTERFERON A/ REVERSIBLY CONTROLS HIGH PROLIFERATIVE POTENTIAL-QUIESCENT HUMAN MESENCHYMAL STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Peiffer, Isabelle, Barbet, Romain, Hatzfeld, Jacques, Li, Ma Lin, Eid, Pierre, Oostendorp, Robert A. J., Haydont, Valrie, Fortunel, Nicolas, Charbord, Pierre, Tovey, Michael, Hatzfeld, Antoinette SUN - 120: HUMAN CARDIAC STEM CELLS THERE IS A POOL OF ENDOGENOUS RESIDENT C-KIT+ PROGENITORS IN THE RIGHT ATRIUM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Garbade, Jens, Arsalan, Mani, Woiteck, Felix, Adams, Volker, Walther, Thomas, Mohr, Friedrich-Wilhelm SUN - 121: CHARACTERISATION OF HUMAN FETAL CARDIAC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Alfakir, Marah, Robson, Stephen C., Dawe, Nicholas, Meeson, Annette P. SUN - 122: INTERACTIONS OF HUMAN TERM PLACENTA-DERIVED MULTIPOTENT CELLS (PDMCS) WITH LYMPHOCYTES OF THE INNATE AND ADAPTIVE IMMUNE SYSTEM . . . . . . . . . . . . . . . . . . 7 Chang, Chan-Jung, Yen, Men-Luh, Chen, Yao-Chang, Chien, Chin-Cheng, Huang, Hsing-I, Yen, Betty LinJu SUN - 123: EPIGENETIC MARKS OF LINEAGE SPECIFIC GENE PROMOTERS IN HUMAN ADIPOSE STEM CELLS . . . . . . . . . . . . . . 7 Noer, Agate, Boquest, Andrew C., Srensen, Anita L., Vekterud, Kristin, Collas, Philippe SUN - 124: THE PROLIFERATION AND DIFFERENTIATION CAPACITY OF HUMAN ADIPOSE TISSUE-DERIVED STEM CELLS AMONG DIFFERENT INDIVIDUALS . . . . . . . . . . . . . . . . . . . . . . . . . 7 Choy, Kwong-Wai, Ng, Wing Chi, Wang, Chi-Chiu, Lui, W.T., Liu, Y.M., Yip, S.K. SUN - 125: PHENOTYPE STABILITY IN RETINAL PIGMENT EPITHELIAL CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Clegg, Dennis O., Buchholz, David, Hikita, Sherry, Radeke, Montgomery, Johnson, Lincoln V. SUN - 126: EFFICIENT DERIVATION OF XENO-FREE HUMAN EMBRYONIC STEM CELL LINES FROM FRESH EMBRYOS FOLLOWING PREIMPLANTATION GENETIC DIAGNOSIS (PGD) . . . 8 French, Andrew J., Adams, Catharine A., Anderson, Linda S., Wood, Samuel H. SUN - 127: IDENTIFICATION OF THE CD MARKER ASSOCIATED WITH DIFFERENTIATION POTENTIAL OF HUMAN BONE MARROW STROMAL CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Fukiage, Kenichi, Aoyama, Tomoki, Shibata, Kotaro Robert, Otsuka, Seiji, Furu, Moritoshi, Nakamura, Takashi, Toguchida, Junya SUN - 128: HUMAN UMBILICAL CORD PERIVASCULAR CELLS (HUCPVCS) AS STROMA FOR HEPATOCYTES . . . . . . . . . . . . . . . . . 9 Gomez-Aristizabal, Alejandro, Davies, John E. SUN - 129: UNDERSTANDING THE SELF RENEWAL PROPERTY OF HUMAN MAMMARY EPITHELIAL STEM CELLS . . . . . . . . . . . . . 9 Dey, Devaveena SUN - 130: IDENTIFICATION AND CHARACTERIZATION OF MAMMARY STEM/PROGENITOR CELLS IN HUMAN BREAST MILK . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Fan, Yiping, Chan, Jerry, Chong, Yap Seng, Cregan, Mark Derek, Choolani, Mahesh

CHARACTERIZATIONS OF TISSUE SPECIFIC STEM CELLS. 4SUN - 114: MESENCHYMAL STEM CELL LIKE PROPERTIES OF LIMBAL STROMAL CELLS OF HUMAN EYE. . . . . . . . . . . . . . . . . . . 4 Vemuganti, Geeta K., Fatima, Anees, Polisetty, Naresh, Chelluri, Lakshmi Kiran, Madhira, Soundary Lakshmi, Sangwan, Virender S. SUN - 115: LOCALIZATION AND CHARACTERIZATION OF HUMAN MESENCHYMAL STEM CELLS FROM FIRST TRIMESTER AND TERM PLACENTA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Castrechini, Natalie M., Murthi, Padma, Brennecke, Shaun P., Kalionis, Bill SUN - 116: COORDINATED CHANGES OF MITOCHONDRIAL BIOGENESIS AND ANTIOXIDANT ENZYMES DURING OSTEOGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS . . . . 5 Chen, Chien-Tsun, Shih, Yu-Ru V., Kuo, Tom K., Lee, Oscar K., Wei, Yau-Huei

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Table of ContentsSUN - 131: MICRORNA-MEDIATED CELL CYCLE CONTROLS IN HUMAN AND MOUSE ADULT STEM AND TRANSIT-AMPLIFYING CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Arnold, Christopher P., Chen, Chang-Zheng SUN - 132: COMMITTED AND SELF-RENEWABLE CARDIAC MESOANGIOBLASTS ARE DERIVED FROM VESSELS OF JUVENILE MOUSE VENTRICLE. . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Galvez, Beatriz G., Sampaolesi, Maurilio, Covarello, Diego, Crippa, Stefania, Latini, Roberto, Cossu, Giulio SUN - 133: DOWN REGULATION OF MRNA TRANSCRIPTION IN MELANOCYTE AND KERATINOCYTE STEM CELLS IN THE MOUSE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Freter, Rasmus, Osawa, Masatake, Nishikawa, Shin-Ichi SUN - 134: GENETIC ANALYSIS OF RETINAL PROGENITOR/STEM CELLS SELF-RENEWAL IN MICE . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Bernier, Gilbert, Duparc, Robert-Hugues, Ttreault, Nicolas, Chatoo, Wassim SUN - 135: ADULT MOUSE RETINAL STEM CELLS RECAPITULATE AN EARLY DEVELOPMENTAL STAGE OF RETINAL PROGENITOR CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Arsenijevic, Yvan, Bollotte, Frederic, Djojosubroto, Meta SUN - 136: INDUCTION OF PHOTORECEPTOR TRANSCRIPTION FACTOR CONE-ROD HOMEOBOX (CRX) EXPRESSION IN MOUSE POSTNATAL RETINAL STEM CELLS (RSCS) . . . . . . . . . . . . . . . . . . 11 Canola, Kriss, Wanner, Dana, Takahashi, Masayo, Arsenijevic, Yvan SUN - 137: INCREASED CHROMOSOMAL INSTABILITY IN MOUSE RETINAL STEM CELLS ALONG EXTENSIVE PASSAGING. . . . . . . . 11 Djojosubroto, Meta, Tekaya, Meriem, Wanner, Dana, Arsenijevic, Yvan SUN - 138: IDENTIFICATION AND CHARACTERIZATION OF ACTIVE STEM CELLS IN MOUSE MAMMARY TISSUE IN VIVO. . . 12 Bai, Lixia, Rohrschneider, Larry R. SUN - 140: NEUROPEPTIDE Y (NPY) AND THE Y1 RECEPTOR ARE REQUIRED FOR THE PROLIFERATION OF ADULT MOUSE OLFACTORY PRECURSORS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Doyle, Kharen L., Hort, Yvonne, Shine, John, Herzog, Herbert SUN - 142: COLLAGEN FIBERS ARE ORGANIZED AS PERPENDICULAR BUNDLES AMONG THE BONE CELLS BEING DIFFERENTIATED FROM CANINE MSCS . . . . . . . . . . . . . . . . . . . . 12 Baghaban Eslaminejad, Mohamadreza, Nickmahzar, Aghbibi, Dehghan, Mohammadmehdy, khojasteh, Arash, Jafarian, Mohammad SUN - 143: EXPRESSION OF THY 1.2 SURFACE ANTIGEN INCREASES SIGNIFICANTLY DURING THE MURINE MSCS CULTIVATION PERIOD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Baghaban Eslaminejad, Mohamadreza, Nadri, Samad, Hajji Hosseini, Reza SUN - 144: THE ROLE OF HYALURONAN WITHIN THE HEMOPOIETIC STEM CELL NICHE OF ADULT MURINE BONE MARROW. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Ellis, Sarah, Williams, Brenda, Asquith, Steve, Rutherford, Kate E., Camenisch, Todd D., Haylock, David N., Bertoncello, Ivan, Nilsson, Susie K. SUN - 145: IN VITRO CHARACTERIZATION OF ADULT MURINE HEART-DERIVED SCA-1+/PDGFRA+/PECAM1CARDIAC PROGENITOR CELL POPULATION. . . . . . . . . . . . . . . . . . . . . . . . . . 14 Chandrakanthan, Vashetharan, Li, Joan, Prall, Owen, Xaymardan, Munira, Harvey, Richard P. SUN - 146: PAIRED IG-LIKE RECEPTORS AS REGULATORS OF MURINE HEMATOPOIETIC STEM CELL FUNCTION . . . . . . . . . . . . 14 Chen, Ching-Cheng, Heffner, Garrett C., Chan, Charles K. F., Tsai, Mindy, Cooper, Max D., Galli, Stephen J., Weissman, Irving L. SUN - 147: ISOLATION AND CHARACTERIZATION OF HEPATIC MURINE OVAL CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Erker, Laura, Dorrell, Craig, Grompe, Markus SUN - 148: SOMATIC STEM CELLS FROM ADULT SKIN TISSUE: COMPARATIVE STUDY OF ISOLATION AND CULTIVATION METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Ancans, Janis, Cakstina, Inese, Riekstina, Una, Muceniece, Ruta, Pirags, Valdis, Muiznieks, Indirkis SUN - 149: COMPARISON OF PROLIFERATION, DIFFERENTIATION POTENTIAL, AND GENE EXPRESSION PATTERN OF SKIN-AND BRAIN-DERIVED PORCINE FETAL STEM CELLS . . . . . . . . . . . . . . . 15 Dyce, Paul W., Stewart, Jennifer, Cheung, Queenie C.K., Squires, E. James, Li, Julang SUN - 150: COMBINED INFLUENCE OF ANOXIA/HYPOXIA AND LOW GLUCOSE ON CELL PHYSIOLOGY AND PLASTICITY OF PORCINE DENTAL PULP STEM CELLS . . . . . . . . . . . . . . . . . . . . . . 15 Agata, Hideki, Kagami, Hideaki, Ueda, Minoru SUN - 151: ASSESSMENT OF THE REGENERATIVE POTENTIAL OF PDGFRA+ INTERSTITIAL CELLS IN THE HEART AND THEIR FLUX AFTER ISCHAEMIC INJURY . . . . . . . . . . . . . . . . . . . . . . . . . 15 Ahmed, Ishtiaq M., Chandrakanthan, Vashetharan, Xaymardan, Munira, Prall, Owen WJ, Li, Joan, Kollar, Kate, Blair, Christopher AJ, Harvey, Richard P. SUN - 152: EFFECT OF ELECTRICAL STIMULATION ON NEURAL STEM CELL GROWTH AND DIFFERENTIATION . . . . . . . . . . . . . . . 16 Ariza, Carlos A., Mallapragada, Surya K., Sakaguchi, Donald SUN - 153: GATA-3 IS AN ESSENTIAL REGULATOR OF STEM AND PROGENITOR CELLS IN THE MAMMARY GLAND . . . . . . . . . . . . . 16 Asselin-Labat, Marie-Liesse, Sutherland, Kate D., Barker, Holly, Thomas, Richard, Shackleton, Mark, Hartley, Lynne, Robb, Lorraine, Grosveld, Frank G., van der Wees, Jacqueline, Lindeman, Geoffrey J., Visvader, Jane E. SUN - 154: ULTRASTRUCTURAL ANALYSIS OF RETINAL STEM CELLS DERIVED FROM THE MAMMALIAN CILIARY EPITHELIUM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Cicero, Samantha A., Dyer, Michael A. SUN - 156: ROLE OF NR4A2 IN HEMATOPOIESIS . . . . . . . . . . . . . 16 Sirin, Olga, Conneely, Orla, Goodell, Margaret SUN - 157: ASSESSMENT OF THE ROLE OF MKL1 IN MEGAKARYOCYTIC DIFFERENTIATION. . . . . . . . . . . . . . . . . . . . . 17 Cheng, Ee-Chun, Renda, Matthew J., Wang, Lin, Krause, Diane S. SUN - 158: ISOLATION AND CHARACTERIZATION OF NEURAL STEM/PROGENITOR CELLS USING AN FGF1 PROMOTOR FUSED WITH FLUORESENT REPORTER PROTEINS . . . . . . . . . . . . . . . . . . . 17 Chiu, Ing-Ming,, Lee, Don-Ching, Chen, Su-Liang, Hung, Min-Pao SUN 159: WNT SIGNALING REGULATES PROLIFERATION OF INTESTINAL PROGENITOR CELLS AND IS DIFFERENTIALLY STIMULATED IN RESPONSE TO INJURY . . . . . . . . . . . . . . . . . . . . 17 Davies, Paige S., Powell, Anne E., Carroll, Kevin H., Doherty, Jason M., Stappenbeck, Thaddeus S., Wong, Melissa H. SUN - 160: EFFECTS OF SIRT1 DEFICIENCY ON GERM CELL DEVELOPMENT AND FUNCTION . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Coussens, Matthew J., Yamazaki, Yukiko, Maeda, Gregg, Yanagimachi, Ryuzo, Allsopp, Richard SUN - 161: ISOLATION AND IDENTIFICATION OF NEONATAL CATTLE MALE GERM STEM CELLS (MGSCS) . . . . . . . . . . . . . . . . 18 Dong, Wuzi, Dou, Zhongying SUN - 162: MOLECULAR SIGNATURE OF QUIESCENT SATELLITE CELLS IN ADULT SKELETAL MUSCLE . . . . . . . . . . . . . . . . . . . . . . 19 Fukada, So-Ichiro, Yamamoto, Hiroshi, Miyagoe-Suzuki, Yuko, Takeda, Shinichi SUN - 164: THE RUNX1 EXPRESSION DRIVEN BY THE PROXIMAL PROMOTER IS CRITICAL FOR POSTNATAL DEVELOPMENT . . . . . 19 Samokhvalov, Igor M., Nishikawa, Shin-ichi

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Table of ContentsSUN - 165: THE P47 GTPASE LRG-47 LINKS HOST DEFENSE AND HEMATOPOIETIC STEM CELL PROLIFERATION . . . . . . . . . . . . . . . 19 Weksberg, David C., Feng, Carl G., Sher, Alan, Goodell, Margaret A. SUN - 166: THE EPIBLAST CONTAINS STABLY PROGRAMMED SKELETAL MUSCLE STEM CELLS THAT REGULATE DIFFERENTIATION IN THE SOMITES . . . . . . . . . . . . . . . . . . . . . . . 19 Gerhart, Jacquelyn V., Elder, Justin, Neely, Christine, Pfautz, Jessica, Perlman, Jordanna, Narciso, Luis, Linask, Kersti, Knudsen, Karen, George-Weinstein, Mindy SUN - 167: DE NOVO GENERATION OF HEPATIC AND BILIARY CELLS IN VITRO FROM A PANCREATIC ADULT CELL POPULATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Stevenson, Karen S., Bukowski-Wills, Jimi-Carlo, Hodge, Maxine, McLinden, Hayley, George, W.D., Davies, R. Wayne, Shiels, Paul G.

CONTROLLED DIFFERENTIATION TO ENDODERMAL DERIVATIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22SUN - 181: ISOLATION AND EXPRESSION PROFILING OF HESC DERIVED HEPATOCYTE-LIKE CELLS. . . . . . . . . . . . . . . . . . . . . . . . 22 Chiao, Eric, Elezar, Menashe, Xing, Yi, Xiong, Anming, Kmet, Muriel, Glenn, Jeff, Wong, Wing, Baker, Julie SUN - 182: HUMAN UMBILICAL CORD BLOOD-DERIVED CELLS GENERATE INSULIN-PRODUCING CELLS IN VITRO . . . . . . . . . . . . 23 Choi, Dongho, Cheong, Hee Jeong, Kim, Sook Ja, Lim, Mi Sun, Won, Jong Ho, Park, Hyung Kyu SUN - 183: DNA METHYLATION STATUS OF SOME DEFINITIVE ENDODERM-SPECIFIC GENES DURING DIRECTED DIFFERENTIATION OF HESC CLONAL LINES BY ACTIVIN A . . . . . 23 Chung, Henry, Sidhu, Kuldip S., Tuch, Bernard E. SUN - 184: FUNCTION OF THE TRANSCRIPTION FACTOR HEX IN HUMAN EMBRYONIC STEM CELL DEVELOPMENT . . . . . . . . . . . . 23 Touboul, Thomas, Alexander, Morgan, Pedersen, R. A., Weber, Anne, Vallier, Ludovic SUN - 185: SIGNALLING PATHWAYS CONTROLLING THE DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO DEFINITIVE ENDODERM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Touboul, Thomas, Vallier, Ludovic, Weber, Anne, Pedersen, R.A. SUN - 186: GENERATION OF A FLUORESCENT REPORTER GENE KNOCK-IN CELL LINE FOR ENHANCED DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO ENDODERM-DERIVED LUNG CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Goulburn, Adam, Giudice, Antonietta, Trounson, Alan SUN - 187: DEVELOPMENT OF FULLY DEFINED CULTURE CONDITIONS FOR THE IN VITRO DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS TO DEFINITIVE ENDODERM . . . . . . . . 24 Heath, Oliver, Tellis, Irene, Jamshidi, Pegah, Pera, Martin F., Hawes, Susan M. SUN - 188: A STROMAL CELL LINE INDUCES HUMAN EMBRYONIC STEM CELL COMMITMENT AND DIFFERENTIATION INTO HEPATIC ENDODERM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Herpe, Yves-Edouard, Barbet, Romain, Zhou, Yi-Ping, Monier, Marie-Nolle, Weber, Anne, Hatzfeld, Antoinette, Hatzfeld, Jacques, Labi, Yacine SUN - 189: MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC PROGENITOR CELLS ENGRAFT IN RECIPIENT LIVERS WITH LIMITED CAPACITY OF LIVER TISSUE FORMATION . . . . . . . . . . . 25 Cantz, Tobias, Sharma, Amar Deep, Vogel, Arndt, Schambach, Axel, Haridass, Dhivya, Bleidissel, Martina, Schoeler, Hans Robert, Ott, Michael SUN - 190: GENERATION OF A MOUSE SURFACTANT PROTEIN C FLUORESCENT REPORTER KNOCK-IN EMBRYONIC STEM CELL LINE TO MARK DERIVATIVES OF THE RESPIRATORY LINEAGE . . 25 Giudice, Antonietta,,Bruce, Amanda, Van Vranken, Ben, Trounson, Alan, SUN - 191: ISLET NEOGENESIS THROUGH CHICK B- ISLET DERIVED STELLATE CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Datar, Savita P., Bhonde, Ramesh R.

CONTROLLED DIFFERENTIATION TO ECTODERMAL DERIVATIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20SUN - 168: LENTIVIRAL DELIVERY OF LMX1A INTO HUMAN BONE MARROW MESENCHYMAL STEM CELLS DIRECTS DIFFERENTIATION TOWARDS DOPAMINERGIC PRECURSORS . . . 20 Offen, Daniel, Barzilay, Ran, Ben-Zur, Tali, Bulvik, Shlomo, Melamed, Eldad SUN - 169: DOPAMINERGIC DIFFERENTIATION OF A HUMAN NEURAL STEM CELL LINE IN CO-CULTURE WITH RAT STRIATAL BRAIN SLICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Anwar, Mohammad Raffaqat, Andreasen, Christian M., Zimmer, Jens, Martinez-Serrano, Alberto, Meyer, Morten SUN - 170: CLONAL DERIVATION AND EXPANSION OF NEURAL STEM CELLS FROM HUMAN EMBRYONIC STEM CELLS . . . . . . . . 20 Arntfield, Margot E., Chaddah, Radha, Runciman, Sue, Smukler, Simon, van der Kooy, Derek SUN - 171: EXPLORING NEURAL DIFFERENTIATION AND DIVERSITY WITH HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . 21 Carson, Christian T., Yeo, Gene, Gage, Fred H. SUN - 172: TRANSPLANTATION OF DOPAMINE NEURONS FROM HUMAN EMBRYONIC STEM CELLS TREATED WITH NOGGIN . . . . 21 Chiba, Shummei, Lee, Youngmook, Zhou, Wenbo, Freed, Curt R. SUN - 173: REGULATION OF ES CELL DIFFERENTIATION TO THE MIDBRAIN DOPAMINE NEURON PHENOTYPE: TRANSCRIPTION FACTORS AND MICRORNAS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Abeliovich, Asa, Kim, Jongpil SUN - 174: OVEREXPRESSION OF THE LIM DOMAIN ONLY PROTEIN LMO2 IN THE SPINAL CORD PRECURSOR CELLS. . . . . . 21 Ahn, Joon-Ik, Bang, Hye Jin, Ko, Moon Jeong, Kim, So Young, Jeong, Ho Sang, Chung, Hye Joo SUN - 175: HYPOXIA ENHANCES THE DERIVATION OF NEURAL STEM CELLS FROM MOUSE EMBRYONIC STEM CELLS IN A DEFAULT ASSAY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Clarke, Laura, van der Kooy, Derek SUN - 176: DEHYDROEPIANDROSTERONE (DHEA) ENHANCES PROLIFERATION BUT NOT NEUROGENESIS IN NEURAL PROGENITORS DERIVED FROM MOUSE EMBRYONAL CARCINOMA STEM CELLS (P19) . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Azizi, Hossein, Zare Mehrjardi, Narges, Kazemi Ashtiani, Saied, Bahmani, Mirza Khalil, Hatami, Maryam, Baharvand, Hossein SUN - 179: INVOLVEMENT OF ER STRESS RESPONSE IN THE DIFFERENTIATION OF ADULT STEM CELLS . . . . . . . . . . . . . . . . . . 22 Cho, Yoon Mi, Jang, Young-Min, Jang, Yoon Sung, Kwon, Oh-Joo SUN - 180: NEURAL INDUCTION AND SUBTYPE NEURONAL PATTERNING VIA NOVEL SMALL MOLECULE TREATMENT . . . . . 22 Clark, Julie H., Ding, Sheng

CONTROLLED DIFFERENTIATION TO MESODERMAL DERIVATIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26SUN - 192: DIFFERENTIATION AND ENRICHMENT OF CARDIOMYOCYTES FROM HUMAN EMBRYONIC STEM CELLS IN DEFINED CULTURE CONDITIONS . . . . . . . . . . . . . . . . . . . . . . . 26 Rust, William, Graichen, Ralph, Xu, Joya Xiuqin, Sun, William, Colman, Alan, Davidson, Bruce, Zweigerdt, Robert

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Table of ContentsSUN - 193: MOLECULAR PROFILING OF HUMAN EMBRYONIC STEM CELL (ESC)-DERIVED LYMPHOHEMATOPOIETIC PROGENITORS REVEAL ALTERED EXPRESSION OF GENES ASSOCIATED WITH HEMATOPOIETIC STEM CELL (HSC) SELF-RENEWAL AND SURVIVAL . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Salvagiotto, Giorgia, Vodyanik, Maxim A., Ruotti, Victor, Stewart, Ronald, Zhao, Yun, Marra, Marco A., Thomson, James A., Eaves, Connie J., Slukvin, Igor I. SUN - 194: GENETIC MANIPULATION OF MESENCHYMAL STEM CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS RESULTS IN VASCULAR CELL ENRICHMENT . . . . . . . . . . . . . . . . . 27 Sela, Yogev, Beck, Gilad, Flugelman, Moshe, Itskovitz-eldor, Joseph SUN - 195: EARLY STAGES OF HUMAN KIDNEY DEVELOPMENT: CHARACTERISATION OF NEPHRON PROGENITOR CELLS . . . . . . . 27 Gilbert, Thierry, Williams, Georgia, Gardiner, Brooke, Grimmond, Sean, Tuch, Bernard, Little, Melissa SUN - 199: DISSECTING THE ROLE OF TGF AND WNT SIGNALING IN MESODERM FORMATION FROM HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Wang, Yi, Tanaka, Makoto, Nakayama, Naoki SUN - 200: DIFFERENTIATION POTENTIAL OF HIGHLY PURIFIED CD34 POSITIVE AS WELL AS NEGATIVE CELLS INTO ENDOTHELIAL PROGENITOR CELLS OF HUMAN UMBILICAL CORD BLOOD . . . . 28 Yoon, Jin-Wook, Nam, Hyun, Lee, Gene, Cho, Jaejin SUN - 201: KIDNEY GENE EXPRESSION WITHIN MOUSE EMBRYOID BODIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Bruce, Stephen, Steptoe, Anita, Busslinger, Meinrad, Perkins, Andrew SUN - 202: BMP-2, BMP-6 AND BMP-7 IMPROVE TGF-B3 INDUCED CHONDROGENESIS OF MOUSE BONE MARROW STROMAL CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Taipaleenmki, Hanna, Laitala-Leinonen, Tiina, Hentunen, Teuvo, Smnen, Anna-Marja SUN - 203: STRUCTURAL PROPERTY OF FIBRIN INFLUENCE ON ENDOTHELIAL CELL DIFFERENTIATION OF ADIPOSE TISSUEDERIVED STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Yang, Young-Il, Kim, Hyeong-In, Seo, Ji-Yeon SUN - 204: FROM STEM CELLS TO CARDIAC PROGENITOR CELLS POTENTIAL FOR THERAPEUTIC APPLICATION . . . . . . . . . . . . . 29 Shatapathy, Chetan C., Minger, Stephen L. SUN - 205: FUNCTIONAL IMPROVEMENT OF MUSCULAR DYSTROPHIC MICE ENGRAFTED WITH ES CELL-DERIVED MYOGENIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Yang, Baoli, Qu, Jing, Cao, Xiao Renee SUN - 206: BERBERINE PROMOTES OSTEOBLAST OIFFERENTIATION THROUGH P38 PATHWAY . . . . . . . . . . . . . . . . 30 Lee, Hyun Woo, Kim, Jae Bum SUN - 210: KNOCKDOWN OF SMADS IN HUMAN EMBRYONIC STEM CELLS BY AN INDUCIBLE SHRNA SYSTEM. . . . . . . . . . . . . 31 Avery, Stuart, Zafarana, Gaetano, Andrews, Peter SUN - 211: DERIVATION OF HUMAN EMBRYONIC STEM CELL LINES ON HUMAN FEEDERS OUR EXPERIENCE . . . . . . . . . . . . 31 Bhartiya, Deepa, Kumar, Neeraj, Desai, Sadhana, Mangoli, Vijay, Nagvenkar, Punam, Tripathi, Shashank, Hinduja, Indira, Padgaonkar, Shreyas, Puri, Chander SUN - 212: DECIPHERING RETT SYNDROME MECHANISMS USING GENETICALLY MODIFIED MECP2 DEFICIENT HUMAN NEURONS DERIVED FROM HUMAN EMBRYONIC STEM CELLS (HESC) . . . . 31 Blanchi, Bruno, Wu, Hao, Sudhof, Thomas, Sun, Yi E. SUN - 213: EFFICIENCY OF ALTERNATIVE CULTURE SYSTEMS FOR THE MAINTENANCE OF HUMAN EMBRYONIC STEM CELLS . . . . 32 Caron, Nicolas J., Wijaya, Hendra, Chaudhry, Muhammad Arshad, Sherwood, Chris, Piret, James M. SUN - 214: EFFECTS OF ETHANOL AND DMSO ON EMBRYOID BODY FORMATION FROM THE HUMAN EMBRYONIC CARCINOMA CELL LINE NCCIT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Chak, Li-Ling, Chan, Woon-Khiong SUN - 215: IDENTIFICATION OF TRANSCRIPTION FACTORS REGULATING NANOG IN PLURIPOTENT HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Chan, Ken Kwok Keung, He, Huining, Sim, Hui Shan, Wu, Selena M., Oh, Steve K.W., Choo, Andre B.H. SUN - 216: AUTOGENEIC FEEDERS SUPPORT THE UNDIFFERENTIATED GROWTH OF HUMAN EMBRYONIC STEM CELLS IN FEEDER AND FEEDER-FREE CONDITIONS . . . . . . . . . . . 33 Choo, Andre Boon Hwa, Ang, Sheu Ngo, Ding, Vanessa, Oh, Steve K.W., Lim, Sai Kiang SUN - 217: ROLE OF EXOGENOUS FGF-2 ON THE MAINTENANCE OF HESC PLURIPOTENCY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Ding, Vanessa M.Y., Cool, Simon M., Haupt, Larisa M., Yap, Miranda G.S., Choo, Andre B.H. SUN - 218: EXPRESSION RESEARCH FOR A NOVEL HUMAN PESCRG1(DPPA2) GENE AS A CANDIDATE GENE MAINTAINING THE UNDIFFERENTIATED STATE OF HESCS . . . . . . . . . . . . . . . . . . 33 Du, Juan, Chen, TianJi, Lu, GuangXiu SUN - 219: REGULATION OF GALANIN IN HUMAN EMBRYOS AND HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . 34 El-Bareg, Aisha M., Brison, Daniel R., Kimber, Susan J. SUN - 220: EFFECTS OF TGF- AND BMP-2 ON THE CHONDROGENIC DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 Elin, Y. Murat, Inan, Blend, Elin, A. Eser SUN - 221: THE CELL CYCLE REGULATORY APPARATUS OF HUMAN EMBRYONIC STEM CELLS AND ITS INTERACTION WITH FGF-2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 Filipczyk, Adam A., Laslett, Andrew L., Mummery, Christine L., Pera, Martin F. SUN - 222: CHARACTERIZING NANOG SIGNALING PATHWAYS IN HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . 35 Fischer, Yvonne, Sthlberg, Anders, Semb, Henrik SUN - 223: DISSECTING THE ROLE OF SOX2 IN HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Fong, Helen, Hohenstein, Kristi A., Donovan, Peter J. SUN - 224: P53 MEDIATED APOPTOSIS OF HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Grandela, Catarina, Pera, Martin F., Wolvetang, Ernst J.

EMBRYONIC STEM CELL BIOLOGY . . . . . . . . . . . . . . . . . 30SUN - 207: HUMAN EMBRYONIC STEM CELLS OVEREXPRESS AURORA B AT LEVELS SIMILAR TO CANCER CELLS AND DISPLAY FREQUENT MITOTIC ERRORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Navara, Christopher, Mich-Basso, Jody, Redinger, Carrie, Ben-Yehudah, Ahmi, Momcilovic, Olga, Simerly, Calvin, Schatten, Gerald SUN - 208: DPPA4 A GENETIC FACTOR ASSOCIATED WITH PLURIPOTENCY IN HUMAN EMBRYONIC STEM CELLS AND HUMAN EMBRYONIC CARCINOMA CELLS . . . . . . . . . . . . . . . . . 30 Abu Dawud, Raed, Andrews, Peter W. SUN - 209: IDENTIFICATION OF HUMAN OOCYTE AND EMBRYONIC STEM CELL REPROGRAMMING FACTORS . . . . . . . . 30 Ambartsumyan, Gayane, Clark, Amander T.

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Table of ContentsSUN - 225: DEVELOPMENT OF DEFINED MEDIUM FOR HUMAN ES CELL CULTURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Furue, Miho K., Na, Jie, Jackson, Jamie P., Okamoto, Tetsuji, Baker, Duncan, Hata, Ryu-Ichiro, Moore, Harry D., Sato, J. Denry, Andrews, Peter W. SUN - 226: AUTOPHAGY IN HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Grandela, Catarina, Tra, Thien, Gong, Lan, Prescott, Mark, Devenish, Rod, Wolvetang, Ernst SUN - 227: REPROGRAMMING HUMAN FETAL FIBROBLASTS TO PLURIPOTENT STATE AFTER FUSION WITH HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Han, Jinnuo, Sidhu, Kuldip S. SUN - 228: ADIPOCYTE DIFFERENTIATION IN A VIRALLY TRANSDUCED HUMAN EMBRYONIC STEM CELL LINE . . . . . . . . . 36 Hannan, Nicholas R.F., Wolvetang, Ernst J. SUN - 229: CHARACTERISATION OF TWO HUMAN EMBRYONIC STEM CELL LINES CARRYING THE HUNTINGTONS DISEASE MUTATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Niclis, Jonathan C., Trounson, Alan, Dottori, Mirella, Verlinsky, Yury, Cram, David SUN - 230: DERIVATION OF 10 PEDIGREED NON-HUMAN PRIMATE EMBRYONIC STEM CELLS (MACACA MULATTA), DERIVATION SUCCESS IS DIRECTLY RELATED TO RATE OF DEVELOPMENT IN VITRO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Navara, Christopher, Mich-Basso, Jody, Redinger, Carrie, Ben-yehudah, Ahmi, Jacoby, Ethan, Sukhwani, Meena, Orwig, Kyle, Castro, Carlos, Simerly, Calvin, Schatten, Gerald SUN - 231: REORGANIZATION OF CHROMATIN REMODELING FACTORS IN THE PORCINE EGG AFTER IN VITRO FERTILIZATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Wee, Gabbine, Koo, Deog-Bon, Shin, Sang-Tae, Lee, Kyung-Kwang, Han, Yong-Mahn SUN - 233: SURVIVAL OF PORCINE EPIBLAST CELLS IN CULTURE 37 du Puy, Leonie, Kuijk, Ewart W., Wilschut, Karlijn J., Colenbrander, Ben, Roelen, Bernard A.J., Haagsman, Henk P. SUN - 234: HEAT SHOCK AND THE ROLE OF HEAT SHOCK PROTEINS DURING NEURAL DIFFERENTIATION FROM MURINE EMBRYONAL CARCINOMA STEM CELLS . . . . . . . . . . . . . . . . . . . 38 Afzal, Elahe, Ebrahimi, Marzieh, Arab Najafi, Seied Mahmoud, Baharvand, Hossein SUN - 235: MMTR/DMAP1 IS CRUCIAL FOR THE MAINTENANCE OF PROPER DIFFERENTIATION OF THE MOUSE EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 Han, Su Youne, Shin, June Ho, Kang, Bong Gu, Do, Byung-Rok, Hong, YeonMi, Kim, Chul Geun SUN - 236: IN VITRO DIFFERENTIATION OF P38 MAP KINASE DEFICIENT MOUSE EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . 38 Guo, Yanlin, Ye, Jianming, Rajan, Suja S. SUN - 237: A PROTEOMICS APPROACH TO DISCOVER STEMNESS ASSOCIATED GENES IN MOUSE EMBRYONIC STEM CELLS . . . . . 38 Baharvand, Hossein, Fathi, Ali, Pakzad, Mohammad, Salekdeh, Ghasem Hosseini SUN - 239: MINIMAL REQUIREMENTS FOR MOUSE EMBRYONIC STEM CELL DERIVATION AND PROPAGATION . . . . . . . . . . . . . . . 39 Wray, Jason, Ying, Qi-Long, Nichols, Jenny, Smith, Austin SUN - 240: SYSTEMATIC IDENTIFICATION OF CIS-ACTING SEQUENCES REVEALS NF-Y AS A REGULATOR OF MOUSE EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Chaivorapol, Christina, Grskovic, Marica, Gaspar-Maia, Alexandre, Li, Hao, Ramalho-Santos, Miguel SUN - 241: DOMINANT NEGATIVE RAR MUTANT CAUSES RESISTANCE TO RETINOIC ACID-INDUCED MOUSE ES CELL DIFFERENTIATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Chatzi, Christina, Shen, Sanbing SUN - 242: THE ROLE OF FGF IN REGULATING THE DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS TO NEURONS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Chen, Ching-Wen, Su, Honglin SUN - 243: CHANGES IN THE CONTENT OF ESTROGEN ALPHA AND PROGESTERONE RECEPTORS DURING DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS TO DOPAMINE NEURONS . . . 40 Diaz, Nestor,, Guerra-Arraiza, Christian, Molina, Anayansi, Salazar, Patricia, Camacho-Arroyo, Ignacio, Velasco, Ivan SUN - 244: DOWN REGULATION OF NANOG GENE EXPRESSION IN MOUSE ES AND P19 CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 Dou, Lin, Dou, Zhongying, Li, Jun, Wang, Huayan SUN - 245: DEFINING CONDITIONS AND CHARACTERISING RESPONSES DURING EMBRYONIC STEM CELL DERIVATION . . . . 40 Batlle Morera, Laura, Smith, Austin, Nichols, Jennifer SUN - 246: DIFFERENT FACTOR REQUIREMENTS OF EMBRYONIC STEM CELLS AND MESENCHYMAL STEM CELLS FOR DIFFERENTIATION INTO ADIPOCYTES. . . . . . . . . . . . . . . . . . 41 Asbrock, Nick, Chu, Vi, Cheng, Xun SUN - 247: PRODUCTION AND MAINTENANCE OF EMBRYONIC STEM CELL LINES DERIVED FROM IN VITRO PRODUCED BUFFALO (BUBALUS BUBALIS) EMBRYOS . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Chauhan, Manmohan S., Verma, Vinod SUN - 248: NUCELAR RECEPTORS LXR AND FXR LIGANDS DIFFERENTIATE EMBRYOID BODY INTO SPECIFIC CELL TYPES . . 41 Cho, JaeJin, Lee, Seul-Bee, Cho, Mee-Yong, Yong, Hwanyul, Lee, Gene SUN - 250: THE POTENTIAL OF STEM CELLS FOR AUDITORY NEURON REPLACEMENT IN THE DEAF COCHLEA . . . . . . . . . . . . 41 Coleman, Bryony, de Silva, Michelle, Shepherd, Robert SUN - 251: IN VIVO MULTIPOTENCY OF TRANSGENIC RAT EMBRYONIC STEM-LIKE (ES-LIKE) CELLS . . . . . . . . . . . . . . . . . . . 42 Demers, Simon-Pierre, Yoo, Jae Gyu, Desmarais, Joelle A., Lian, Li, Therrien, Jacinthe, Murphy, Bruce D., Smith, Lawrence C. SUN - 252: DYNAMIC EXPRESSION OF NONCODING RNA DURING EMBRYONIC AND NEURONAL STEM CELL DIFFERENTIATION. . . 42 Dinger, Marcel E., Pang, Ken C., Crowe, Mark, Grimmond, Sean M., Muscat, George E., Bruce, Stephen, Perkins, Andrew C., Mehler, Mark F., Mattick, John S. SUN - 253: CELL PERMEABLE NANOG INDUCES LIF-INDEPENDENT GROWTH OF ES CELLS AND ENHANCED PROLIFERATION OF FIBROBLAST CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Edenhofer, Frank, Peitz, Michael, Winnemller, Dirk, Mnst, Bernhard SUN - 254: CHARACTERIZATION OF CHONDROGENIC DERIVATIVES OF EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Fecek, Christopher, Pasierb, Magdalena, Buttry, Janelle, Hibbard, Nick, Tyranski, Kelli, Sheikh, Hormoz, Perez-Cruet, Mick, Yao, Dong, Svinarich, David M., Chaudhry, G. Rasul SUN - 255: THE STEM CELL KNOWLEDGE BASE AN INTEGRATED INFORMATION RESOURCE FOR STEM CELL RESEARCH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Fong, Xiao Jun, Jiang, Donald, Cheok, Leong Poh, Lim, Heng Yan, Lim, Teng Ting, Chan, Ying Leong, Chuon, Danny, Rao, Mahendra, Rajagopal, Gunaretnam, Yang, Henry He SUN - 256: GENETIC AND EPIGENETIC VARIATIONS IN ES CELL SUBPOPULATIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Furusawa, Tadashi, Ikeda, Mitsumi, Inoue, Fukashi, Ohkoshi, Katsuhiro, Tokunaga, Tomoyuki

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Table of ContentsETHICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44SUN - 257: AN ETHICAL FRAMEWORK FOR CLINICAL TRIALS OF STEM CELL TRANSPLANTATION FOR SPINAL CORD DISORDERS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Mukhida, Karim, Mendez, Ivar SUN - 258: ISSCR SAMPLE RESEARCH CONSENT DOCUMENTS FOR HUMAN BIOLOGICAL MATERIALS PROCUREMENT . . . . . . . . . . . 44 Hyun, Insoo SUN - 259: DISTRIBUTION OF HESC LINES: HOW, WHEN, AND WHERE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 McCormick, Jennifer B., Scott, Christopher T., Owen-Smith, Jason D. SUN - 260: THERAPEUTIC CLONING IN AUSTRALIA: THE PROCESS OF APPROVAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Nemes, Irene, Knott, Joanna M., Tuch, Bernard E. SUN - 270: MICROCHIMERIC FETAL CELLS CONTRIBUTE TO MATERNAL TISSUE REPAIR AFTER MURINE AND HUMAN PREGNANCY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 Fisk, Nicholas M., ODonoghue, Keelin, Amin, Farhana, Sultan, Hanan, Allaf, Faisal, Anderson, Jonathan, Guillot, Pascale, Bou-Gharios, George SUN - 271: EXAMINATION OF MOUSE BONE MARROW CELL POPULATION THAT PARTICIPATE IN HEPATIC FUNCTION REGENERATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 Cho, Kyung Ah, Ju, Sun Young, Cho, Jung Yoon, Jung, Yun Jae, Ryu, Kyung Ha, Cho, Su Jin, Woo, So Youn, Seoh, Ju Young, Kim, Tae Hun, Yoo, Kwon, Han, Ho Seong SUN - 272: TRANSPLANTATION OF EMBRYONIC AND ADULT MULTIPOTENT STEM/PROGENITOR CELLS INTO WEAVER MOUSE CEREBELLUM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 Chen, K. Amy, Zheng, Tong, Scheffler, Bjorn, Goetz, Katrin, Steindler, Dennis A. SUN - 273: HEMATOPOIETIC STEM CELL TRANSPLANTATION AND THYMIC RECONSTITUTION IN THE NOD/SCID/C-/- IMMUNE DEFICIENT MOUSE MODEL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 Cuddihy, Andrew R., Ge, Shundi, Wang, Xiuli, Zhu, Judy, Crooks, Gay M. SUN - 274: ROLE OF PITUITARY HORMONES IN NEUROGENIC EVENTS DURING RECOVERY FROM HYPOXIC-ISCHEMIC INJURY IN THE IMMATURE RAT BRAIN . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Gorba, Thorsten, Scheepens, Arjan, Moderscheim, Tanja, Christophidis, Larissa J., Pathipati, Praneeti, Williams, Christopher E. SUN - 275: BONE FORMATION AND THE ENDOSTEAL STEM NICHES ARE SWITCHED OFF DURING G-CSF AND CYCLOPHOSPHAMIDE INDUCED MOBILIZATION OF HEMATOPOIETIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Levesque, Jean-Pierre, Sims, Natalie A., Winkler, Ingrid G. SUN - 276: COMPARISON OF CHEMOKINE RECEPTOR EXPRESSION ON BONE MARROW AND PLACENTAL MSC . . . . . . . . . . . . . . . . . 50 Brooke, Gary, Atkinson, Kerry SUN - 278: HEMATOPOIETIC STEM CELL MIGRATION ROLE OF THE RHO/ROCK PATHWAY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Fonseca, Ana-Violeta, Bauer, Nicola, Freund, Daniel, Werner, Carsten, Bornhuser, Martin, Corbeil, Denis

GENOMICS AND PROTEOMICS . . . . . . . . . . . . . . . . . . . . 45SUN - 261: REPRESSOR ELEMENT SILENCING TRANSCRIPTION FACTOR REPRESSES EXPRESSION OF MOUSE BRAIN SPECIFIC HOMEOBOX GENE IN NON-NEURONAL CELLS. . . . . . . . . . . . . . . 45 Park, So Yun, Kim, Jae Bum, Han, Yong-Mahn SUN - 262: PEDIGREED PRIMATE EMBRYONIC STEM CELLS EXPRESS HOMOGENEOUS FAMILY-RELATED GENE PROFILES . . . 45 Ben-Yehudah, Ahmi, Navara, Christopher S., Mich-Basso, Jocelyn D., Redinger, Carrie J., Kovkarova-Naumovski, Elizabeta, Kaminski, Naftali, Schatten, Gerald SUN - 263: Q2CHIP, A QUICK AND QUANTITATIVE CHROMATIN IMMUNOPRECIPITATION ASSAY APPLICABLE TO AS FEW AS 100 CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Dahl, John A., Collas, Philippe SUN - 264: CDNA GENE EXPRESSION PROFILING OF CD34+ HAEMOPOIETIC STEM CELLS FROM MOBILIZED PERIPHERAL BLOOD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Flores, Catherine, Welsh, Jonathan, Marley, Stephen, Habib, Nagy, Gordon, Myrtle SUN - 265: A CHROMATIN LANDMARK AND TRANSCRIPTION INITIATION AT MOST PROMOTERS IN HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Guenther, Matthew G., Levine, Stuart, Boyer, Laurie, Jaenisch, Rudolf, Young, Richard A. SUN - 266: EXPRESSION PROFILING OF HESC SPECIFIC MICRORNAS IN VARIOUS HUMAN CANCER CELL LINES . . . . . . . 47 Kim, Kye-Seong, Cho, Wha Ja, Hong, Ki Sung, Lee, Jun Ho, Sin, Jeong Min, Koo, Kyung Hwa, Kim, Jong Soo, Lee, Man Ryul, Rhim, Si Youn SUN - 267: GENE EXPRESSION SIGNATURES FOR DOPAMINERGIC NEUROGENESIS IN NURR1-OVEREXPRESSING HUMAN NEURAL STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Kim, Soo Min, Cho, Soo Young, Lee, Nan Ju, Kim, Seung U., Lee, Young Sik, Lee, Myung Ae

SOURCES OF PLURIPOTENT STEM CELLS . . . . . . . . . . . . 51SUN - 279: DERIVATION AND CHARACTERISATION OF HES CELL LINES ON HUMAN AND MOUSE FIBROBLASTS IN ODENSE, DENMARK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Harkness, Linda, Erb, Karin, Prokhorova, Tatyana, Frandsen, Ulrik, Kassem, Moustapha SUN - 280: ISOLATION AND IDENTIFICATION OF MULTIPOTENT MESENCHYMAL STEM CELLS FROM ADULT HUMAN ANTERIOR CRUCIATE LIGAMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Cheng, Ming-Te, Chen, Wei-Ming, Chen, Tain-Hsiung, Lee, Oscar K. SUN - 281: CD133 EXPRESSING PERICYTE-LIKE CELLS IN HUMAN SKELETAL MUSCLE EXHIBIT MYOGENIC POTENTIAL . . . . . . . . . . 51 Gavina, Manuela, Belicchi, Marzia, Meregalli, Mirella, Farini, Andrea, Parolini, Daniele, Huard, Johnny, Peault, Bruno, Torrente, Yvan SUN - 282: PLASTICITY OF HEPATIC PROGENITOR CELLS ISOLATION FROM RHESUS MONKEY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 Jin, Lifang, Ji, Shaohui, Tang, Xianghui, Guo, Xiangyu, Lu, Yongqing, Chen, Hongwei, Ji, Weizhi SUN - 283: EFFICIENT PRODUCTION AND ANALYSIS OF PRIMATE BLASTOCYSTS DERIVED BY SOMATIC CELL NUCLEAR TRANSFER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 Byrne, James A., Clepper, Lisa, Wolf, Don P., Mitalipov, Shoukhrat M. SUN - 284: AGE RELATED REPROGRAMMING IN MOUSE OOCYTES TO SUPPORT EMBRYONIC STEM CELL DEVELOPMENT . . . . . . . . . 52 Acharya, Rutu, Trounson, Alan, Lacham-Kaplan, Orly

HOMING AND MIGRATION OF STEM CELLS . . . . . . . . . 47SUN - 268: MECHANISMS FOR TRANSENDOTHELIAL MIGRATION OF HUMAN FETAL MESENCHYMAL STEM CELLS . . . . . . . . . . . . . 47 Chan, Jerry, Vijay, Praveen, Lim, Yaw-Chyn, Choolani, Mahesh SUN - 269: CHARACTERIZATION OF HUMAN MESENCHYMAL STEM CELL SUBPOPULATIONS EXPRESSING ADHESION MOLECULES AND GUIDANCE RECEPTORS THAT MEDIATE NEURONAL CELL MIGRATION IN THE CNS . . . . . . . . . . . . . . . . . . 48 DuTreil, Maria F., Phinney, Donald G.

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Table of ContentsSUN - 285: NOVEL PLURIPOTENT STEM CELLS DERIVED FROM POST IMPLANTATION MOUSE AND RAT EPIBLASTS . . . . . . . . . . 53 Brons, I. Gabrielle, Smithers, L., Trotter, M., Chuva de Sousa Lopes, S., Ahrlund-Richter, L., Pedersen, R. A., Vallier, L. SUN - 286: GONOCYTES; ANOTHER SOURCE OF PLURIPOTENT STEM CELLS? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 Aflatoonian, Behrouz, Soleimani, Mehrdad, Aflatoonian, Ali, Aflatoonian, Nastaran, Aflatoonian, Reza, Aflatoonian, Abbas SUN - 287: DERIVATION OF NEW EMBRYONIC STEM CELL LINES FROM PREIMPLANTATION APPLIED EMBRYOS . . . . . . . . . . . . . . 53 Candan, Zafer Nihat, Sertyel, Semra, Yesil, Mesut, Beyazyurek, Cagri, Sariboyaci, Ayla Eker, Kahraman, Semra SUN - 288: HIGHLY PURIFIED HEMATOPOIETIC STEM CELLS GENERATE CARDIOMYOCYTES VIA MYELOID PROGENITORS THROUGH CELL FUSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Fukata, Mitsuhiro, Ishikawa, Fumihiko, Nakamura, Ryu, Akashi, Koichi, Shultz, Leonard D., Harada, Mine SUN - 300: PANCREATIC VASCULARIZATION ELEVATED BY RETINOIC ACID SIGNALING PROMOTES PROGENITOR CELLS TO DIFFERENTIATE INTO MATURE BETA CELLS . . . . . . . . . . . . . . . . . 57 Chien, Chiao-Yun, Wu, Ruei-Ren, Lin, Yu-Hsing, Chen, Jyh-Long, Shen, ChiaNing SUN - 301: INDIAN HEDGEHOG IS REQUIRED FOR DEFINITIVE HAEMATOPOIESIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Cridland, Simon O., Perkins, Andrew C. SUN - 302: CULTURE OF HUMAN LIMBAL STEM CELLS ON AMNIOTIC MEMBRANE OR COLLAGEN WITH BFGF/NOGGIN . . . 58 Ebrahimi, Marzieh, Taghi Abadi, Ehsan, Heidari, Manzar, Javadi, Mohammad Ali, Hosseini Salekdeh, Ghasem, Baharvand, Hossein SUN - 303: CD81 IS ESSENTIAL FOR MURINE HSC REGENERATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Lin, Kuan-Yin K., Benabentos, Rocio, Goodell, Margaret A. SUN - 304: HAEMOPOIETIC MICROENVIRONMENT-DERIVED ANGIOTENSIN II REGULATES MURINE HAEMOPOIESIS . . . . . . . . 58 Jokubaitis, Vanta J., Bertoncello, Ivan, Simmons, Paul J. SUN - 305: DESIGN AND CHARACTERIZATION OF HYDROPHOBIC MATERIALS ENGINEERED TO OPTIMIZE EMBRYOID BODY FORMATION. . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Jonas, Steven J., Valamehr, Bahram, Kam, Korey, Polleux, Julien, Wu, Hong, Dunn, Bruce

STEM CELL MICROENVIRONMENT . . . . . . . . . . . . . . . . . 54SUN - 289: OPTIMISATION OF CULTURE CONDITIONS FOR HUMAN MESENCHYMAL STEM CELLS FOR CLINICAL STEM CELL THERAPY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Haack-Srensen, Mandana, Friis, Tina, Bindslev, Lene Mortensen, Steen, Johnsen, Hans, Kastrup, Jens SUN - 290: CROSSTALK BETWEEN HUMAN MESENCHYMAL STEM CELLS AND GLIOMA CELLS INHIBITS TUMOR PROGRESSION . . 55 Ho, Ivy A.W., Shim, Winston S.N., Chan, Kelly Y.W., Guo, Chang M., Tan, Puay H., Hui, Kam M., Cheang, Philip, Lam, Paula Y.P. SUN - 291: EFFECTS OF HYPOXIA ON HUMAN MESENCHYMAL STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 Hung, Shun-Pei, Kuo, Tom K., Shih, Yu-Ru V., Lee, Oscar K. SUN - 292: COMPARING THE TRANSCRIPTOME OF THE ADULT AND FETAL HEMATOPOIETIC STEM CELL NICHE TO IDENTIFY NOVEL HEMATOPOIESIS EFFECTORS IN THE MOUSE. . . . . . . . . . 55 Brouard, Nathalie, Driessen, Rebecca, Liu, Mira, Simmons, Paul J. SUN - 293: CYTOKINESIS-BLOCK MICRONUCLEUS CYTOME ASSAY IN CULTURED BOVINE SPERMATOGONIAL STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 Hor, Maryam, Dhillon, Varinder, Fenech, Michael SUN - 294: CELL GROWTH AND MORPHOLOGY IN CULTURED BOVINE SPERMATOGONIAL STEM CELLS. . . . . . . . . . . . . . . . . . . 56 Hor, Maryam, Dhillon, Varinder, Fenech, Michael SUN - 295: MAINTENANCE OF ADULT STEM CELL SELF-RENEWAL WITH HEPARAN SULFATE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 Helledie, Torben, Dombrowski, Christian, Lee, Ian, Wan Jin, Hong, Nurcombe, Victor, Cool, Simon M. SUN - 296: THE STEM CELL MARKER PROMININ-1 (CD133) IS RELEASED FROM HEMATOPOIETIC STEM AND PROGENITOR CELLS IN ASSOCIATION WITH SMALL MEMBRANE VESICLES. . . 56 Bauer, Nicola, Wilsch-Bruninger, Michaela, Fonseca, Ana-Violeta, Freund, Daniel, Baust, Thorsten, Bornhuser, Martin, Hoflack, Bernard, Huttner, Wieland, Corbeil, Denis SUN - 297: THE ROLE OF CD48 IN MAINTAINING HEMATOPOIETIC PROGENITOR POOL SIZE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Boles, Nathan C., Bowman, Teresa V., Merchant, Mehveen, Tierney, Megan P., Goodell, Margaret A. SUN - 299: ENCAPSULATION OF HESC AS 3D MODEL TO STUDY THEIR DIRECTED DIFFERENTIATION . . . . . . . . . . . . . . . . . . . . . . . 57 Chayosumrit, Methichit, Sidhu, Kuldip S., Tuch, Bernard E.

STEM CELL TECHNOLOGY. . . . . . . . . . . . . . . . . . . . . . . . 59SUN - 307: COLLAGEN-HUMAN MESENCHYMAL STEM CELL (HMSCS) MICROSPHERES NOVEL BIO-DEVICES FOR CELL DELIVERY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Chan, Barbara P., Chan, G.C.F. SUN - 308: DOPAMINERGIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS UTILIZATION OF BIOASSAY FOR TYROSINE HYDROXYLASE EXPRESSION . . . . . . . . . . . . . . . . . . . 59 Kan, Inna, Barhum, Yael, Ben-Zur, Tali, Charlow, Tirza, Levy, Yossef, Burshtein, Alex, Bulvik, Shlomo, Melamed, Eldad, Offen, Daniel SUN - 309: EFFECTS OF SPECIFIC INTERACTION OF GLYCOPOLYMER WITH HUMAN HEMATOPOIETIC CELLS FROM CORD BLOOD AND PERIPHERAL BLOOD . . . . . . . . . . . . . . . . . . . 60 Kim, Dong-Ku, Park, Keun-Hong, Kim, Tea-Sik, Lee, Yong-Su, Kim, Hye-Sun, Lee, Hyun-Ju, Kim, Yu-Kyung SUN - 310: GENE DELIVERY TO HUMAN ADIPOSE DERIVED STEM CELLS USING POLYETHYLENIMINE . . . . . . . . . . . . . . . . . . . . . . . . 60 Ahn, Hyun hee, Lee, Jung Wha, Kim, Kyung Sook, Cho, Mi Hee, Shin, Yu Na, Kim, Moon Suk, Lee, Il Woo, Khang, Gilson, Lee, Hai Bang SUN - 311: TRANSGENIC ENRICHMENT OF CARDIOMYOCYTES DERIVED FROM HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . 60 Anderson, David, Self, Tim, Goh, Gareth, Hill, Stephen, Denning, Chris SUN - 312: ROBOTIC APPARATUS FOR AUTOMATIC PASSAGE OF HUMAN EMBRYONIC STEM CELL EXPANSION. . . . . . . . . . . . . . . 60 Chen, Wannhsin, Hsu, Lih-Tao, Guu, Yeou-Bin SUN - 313: INHIBITION OF TELOMERASE WITH LENTIVIRUS VECTOR MEDIATED SHORT HAIRPIN RNA INDUCES DIFFERENTIATION OF A HUMAN MESENCHYMAL STEM CELL LINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 Choi, In Young, Shin, Hye-Jin, Yoo, Ji-Hyun, Kim, Seok-Jin, Kim, Byung-Soo SUN - 314: DEVELOPMENT OF ANTI-CANCER NK CELL THERAPY BASED ON HSC DIFFERENTIATION . . . . . . . . . . . . . . . . . . . . . . . . 61 Chung, Jin Woong, Jun, Jun-Ho, Kim, Mi Sun, Yoon, Suk-Ran, Choi, Inpyo SUN - 315: A NOVEL, IMMORTAL, MULTIPOTENT HUMAN NEURAL STEM CELL LINE, GENERATING FUNCTIONAL NEURONS AND OLIGODENDROCYTES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 De Flippis, Lidia, Lamorte, Giuseppe, Snyder, Evan Y., Malgaroli, Antonio, Vescovi, Angelo Luigi vii

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Table of ContentsSUN - 317: LIN- AND CD34+ IMMUNOMAGNETIC SEPARATIONS PROVIDE IDENTICAL ENRICHMENT OF HEMATOPOIETIC STEM CELLS FROM PERIPHERAL BLOOD STEM CELL GRAFTS WHEN COMPARED BY A CDNA MICROARRAY TECHNIQUE DURING EX VIVO CULTURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 Klabusay, Martin, Koutna, Irena, Hrabcakova, Viera, Krontorad, Petr, Mayer, Jiri SUN - 319: DIFFERENTIAL EFFECT OF HORMONE DOSE AND OXYGEN TENSION ON EX VIVO EXPANSION OF ERYTHROID PROGENITORS UNDER SERUM-FREE CONDITIONS. . . . . . . . . . . . 62 Athanasas-Platsis, Stavrosia, Minchinton, Robyn, Sparrow, Rosemary, Nielsen, Lars SUN - 320: GENERATION OF HIGHLY ENRICHED NEURONAL CELLS FROM A RENEWABLE SOURCE OF CELLS (NEURAL STEM CELLS) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 Azari, Hassan, Osborne, Geoffrey W., Yasuda, T., Reynolds, Brent A. SUN - 321: EXPANSION OF BOVINE SPERMATOGONIAL STEM CELLS FOR CELL TRANSFER APPLICATIONS . . . . . . . . . . . . . . . . . 63 Cartledge, Kellie A., Glattauer, Veronica, Werkmeister, Jerome A., Kelley, Bronwyn, Brownlee, Alan G., Herrid, Muren, Davey, Rhonda, Hill, Jon, Hor, Maryam, Fenech, Michael, Ramshaw, John A.M. SUN - 322: BONE MARROW-DERIVED MESENCHYMAL STEM CELLS RECOVER CELLULAR FUNCTION OF THE CELLS WITH SEVERELY COMPROMISED MITOCHONDRIAL FUNCTION . . . . . . 63 Cho, Young Min, Yoo, Dae Hoon, Shin, Dong Hoon, Yoo, Sung Hoon, Park, Kyong Soo, Lee, Hong Kyu SUN - 323: DISCRIMINATION AND MEANINGFUL ENUMERATION OF NEURAL STEM VERSUS PROGENITOR CELLS USING THE NEURAL COLONY FORMING CELL (N-CFC) ASSAY. . . . . . . . . . . . 63 Deleyrolle, Loic P., Louis, Sharon A., Rietze, Rodney L., Wagey, Ravenska E., Thomas, Terry E., Eaves, Allan C., Reynolds, Brent A. SUN - 324: CIRCULATING APOPTOTIC PROGENITOR CELLS: A NOVEL BIOMARKER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 Deutsch, Varda R., Schwartzenberg, Shmuel, Kissil, Sarina, Keren, Gad, George, Jacob SUN - 325: APPLICATIONS OF HIGH CONTENT IMAGING TO STEM CELL BIOLOGY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 Goldsborough, Mindy D., Rohrer, Jurg, Zoellner, Olaf SUN - 326: DEVELOPMENT OF ARTIFICIAL HEMATOPOIETIC STEM CELL NICHE IN VITRO USING BIOMATERIAL MICROARRAYS . . . 64 Esmaeli-Azad, Babak, Federico, Cybele, Martinez, Giraldo, Wing, Luman, Carrier, Ewa

TISSUE ENGINEERING . . . . . . . . . . . . . . . . . . . . . . . . . . . 66SUN - 330: IN VITRO EXPANSION OF HUMAN CHONDROCYTES USING A NOVEL THERMOGELATION POLYMER AND MOLECULAR CHARACTERIZATION . . . . . . . . . . . . . . . . . . . . . . . . 66 Arumugam, Sivaraman, Rao, Manjunath S., Sheriff, Khaleefathullah A., Rajappa, Senthilkumar, Mahalingam, Mohanashankar, Amrithraj, Naveen T., Liyakath, Farzana B., Mori, Yuichi, Yoshioka, Hiroshi, Marthandam, Subakumar, Rajendiran, Swaminathan, SUN - 331: OSTEOGENICALLY DIFFERENTIATED HUMAN MESENCHYMAL CELLS ON THREE DIMENSIONAL HYDROXYAPATITE SCAFFOLDS: A HIGHLY REPRODUCIBLE OSTEOSPHEROID PLATFORM FOR ENHANCED EX VIVO OSTEOGENESIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 Burns, Jorge S., Rasmussen, Pernille, Kassem, Moustapha SUN - 332: HUMAN BONE MARROW MESENCHYMAL STEM CELLS EXPRESSING ENDOBLIN AFTER EX VIVO REPLICATION DEFECTIVE ADENOVIRUS BMP-2 MEDIATED GENE TRANSFER . . . . . . . . . . . 66 Chang, Sophia Chia-Ning, Lin, Tsung-Min, Chung, Hui-Ying, Su, Wen-Pang, Hsiao, Lien-Cheng, Jeng, Long-Bin SUN - 333: TWO- AND THREE-DIMENSIONAL CULTURE CONDITIONS DIFFERENTIALLY AFFECT NEURAL GROWTH FACTOR-INDUCED HUMAN EMBRYONIC STEM CELL DIFFERENTIATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Elin, A. Eser, Inan, Blend, Elin, Y. Murat SUN - 334: MICROENVIRONMENT SPECIFIED LINEAGE COMMITMENT OF MESENCHYMAL PROGENITOR CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . 67 Hwang, Nathaniel S., Varghese, Shyni, Lee, Janice Hyeseung, Zijun, Zhang, Elisseeff, Jennifer SUN - 335: BONE-SPECIFIC EXTRACELLULAR MATRIX PROMOTES THE DIFFERENTIATION OF MESCS TO OSTEOBLASTS . . . . . . . . . 67 Evans, Nicholas D., Gentleman, Eileen, Polak, Julia M., Stevens, Molly M. SUN - 336: IN VIVO OSTEOGENIC DIFFERENTIATION OF RAT BONE MARROW STROMAL CELLS USING INJECTABLE CHITOSAN GELS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 Cho, Mi Hee, Kim, Yu Han, Ahn, Hyun Hee, Shin, Yu Na, Lee, Jung Hwa, Kim, Moon Suk, Lee, Bong, Khang, Gilson, Lee, Hai Bang SUN - 337: DIFFERENTIATION INTO HEPATOCYTES AND MAINTENANCE OF HEPATOCYTE FUNCTIONS BY COCULTURE WITH BONE MARROW STROMAL CELLS . . . . . . . . . . . . . . . . . . . . . . . . 68 Chao, Hsiao-Huei, Lin, Tsung-Min, Chung, Hui-Ying, Hsiao, Lien-Cheng, Su, Wen-Pang, Jeng, Long-Bin, Chang, Sophia Chia-Ning SUN - 338: LIVER TISSUE ENGINEERING USING AN ACELLULAR WHOLE ORGAN BIOSCAFFOLD WITH PERFUSION CELL SEEDING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 Baptista, Pedro M., Atala, Anthony, Soker, Shay SUN - 339: USING HOMEOPROTEINS TO REPROGRAM TARGET CELLS AND INITIATE INSULIN PRODUCTION . . . . . . . . . . . . . . . . 69 Blyth, Nadine J., Gough, Tamara, Vo, Liem T., Kirkland, Christina, Kirkland, Mark A. SUN - 340: EFFECTIVENESS OF HIGHLY OSTEO-DIFFERENTIATED RABBIT MESENCHYMAL STEM CELL-CALCIUM PHOSPHATE CERAMIC COMPOSITE IN POSTERIOR SPINAL FUSION MODEL. . 69 Chan, Chun Wai, Yip, Raymond Churk Lun, Wong, Kenneth Hoi Kin, Lee, Kwong Man, Qin, Ling, Yeung, Hiu Yan, Hu, Yun Yu, Cheng, Jack Chun Yiu SUN - 341: RECONSTRUCTION OF SKIN EQUIVALENTS USING MECHANICAL STIMULATED COLLAGEN MATRIX . . . . . . . . . . . . . 70 Choi, Hye-Ryung, Kang, Youn-A, Cho, Hyun-Joo, Park, Kyoung-Chan SUN - 342: BIPHASIC CONSTRUCTS FOR VASCULAR ENGINEERING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Chong, Mark, Teoh, Swee Hin, Lee, Chuen Neng, Chan, Jerry

ARTIFICIAL NICHES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65SUN - 327: NEW EX VIVO APPROACHES TO GENERATE AND EXPLORE RAT TESTICULAR STEM CELL NICHES . . . . . . . . . . . . . . 65 Gassei, Kathrin, Wood, Michelle A., Walker, William H., Ehmcke, Jens, Schlatt, Stefan SUN - 328: STUDY OF HUMAN LIMBAL STEM CELLS CULTURED ON DIFFERENT MATRICES AND CO-CULTURE SYSTEMS . . . . . . . . . . 65 Ahmadiankia, Naghmeh, Ebrahimi, Marzieh, Baharvand, Hossein, Hosseini, Ahmad SUN - 329: ENGINEERING VASCULARIZED CARDIAC TISSUE USING HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . . . . . . . . . 65 Levenberg, Shulamit, Lesman, Ayelet, Caspi, Oren, Gepstein, Lior

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Table of ContentsSUN - 343: TISSUE ENGINEERING OF THE MESENCHYMAL STEM CELLS IN THE CONSTRUCT POLYCAPROLACTONE-PLURONIC F127 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Chung, Hui-Ying, Lin, Tsung-Min, Chang, Sophia Chia-Ning SUN - 354: EFFECT OF HUMAN UMBILICAL CORD BLOOD DERIVED MESENCHYMAL STEM CELLS ON ENDOGENOUS NEUROGENESIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Park, Sagn In, Jeun, Sin-soo, Lim, Jung Yeon, Jeong, Chang Hyun, Kim, Seong Muk, Jun, Jin Ae, Oh, Won-Il SUN - 355: PRION PROTEIN EXPRESSION AND POLYMORPHIC VARIATION IN HUMAN EMBRYONIC STEM CELLS . . . . . . . . . . . . 74 Pells, Steve, Bishop, M., Todorova, M.G., Stott, J., Ward, J., Head, M.W., De Sousa, Paul SUN - 356: HUMAN STRO-1BRIGHT MESENCHYMAL STEM/STROMAL CELLS EXERT PROLIFERATIVE AND ANTIAPOPTOTIC EFFECTS ON CARDIOMYOCYTES AND ENDOTHELIAL CELLS THROUGH PARACRINE MECHANISMS . . . . . . . . . . . . . . . . 74 Psaltis, Peter J., Zannettino, Andrew C.W., Worthley, Stephen G., Itescu, Silviu, Gronthos, Stan SUN - 358: HUMAN EMBRYONIC STEM CELL DERIVED MOTOR NEURON PROGENITOR CELLS ENHANCE NEURONAL SURVIVAL AND NEURITE OUTGROWTH IN VITRO: IMPLICATIONS FOR SPINAL CORD INJURY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Rossi, Sharyn L., Gutierrez, Adriana, Keirstead, Hans S. SUN - 359: THE SURVIVAL, MIGRATION AND AXON ASSOCIATION OF HUMAN FETAL SPINAL CORD-DERIVED NEURAL PRECURSOR CELLS FOLLOWING IMPLANTATION INTO THE CERVICALLYCONTUSED ADULT RAT SPINAL CORD: INFLUENCE OF IMMUNOSUPPRESSION AND/OR HYPOXIC PRE-CONDITIONING 75 Savant-Bhonsale, Smita, Louro, Jack, Tuesta, Luis M., Pressman, Yelena, Pearse, Damien D. SUN - 360: ACCELERATION OF FULL-THICKNESS WOUND HEALING IN NUDE MICE BY TRANSPLANTATION OF HUMAN AMNIOTIC EPITHELIAL STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Shin, Il-Seob, Kim, Bonghyu, Jung, Ji-Won, Choi, Eun-Wha, Seo, Ju-Yeon, Jo, Jung-Youn, Kim, Yun-Joung, Lee, Sung-Hoon, Kang, Kyung-Sun, Ra, JeongChan SUN - 361: SPINY MOUSE MESENCHYMAL STEM CELLS: ISOLATION AND MULTILINEAGE CHARACTERIZATION . . . . . . . . 76 Milton, Pip, Dickinson, Hayley, Walker, David, Bertoncello, Ivan, Trounson, Alan, Jenkin, Graham SUN - 362: PREVENTION OF ENDOTOXIN-INDUCED ACUTE LUNG INJURY BY BONE MARROW DERIVED MESENCHYMAL STEM CELLS IN MICE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 Rojas, Mauricio, Xu, Jianguo, Mora, Ana L., Brigham, Kenneth L. SUN - 364: INJECTION OF MULTIPOTENT STROMAL CELLS WITHOUT CONCURRENT IMMUNOSUPPRESSION DOES NOT PROLONG HEART GRAFT SURVIVAL IN A RAT ALLOTRANSPLANTATION MODEL . . . . . . . . . . . . . . . . . . . . . . . . . 76 Renner, Philipp, Popp, Felix C., Inoue, Seiichoru, Eggenhofer, Elke, Slowik, Przemyslaw K., Neuwinger, Annette, Geissler, Edward K., Piso, Pompiliu, Schlitt, Hans J., Dahlke, Marc H. SUN - 365: MECHANISM BEHIND LONG-TERM ALLOGRAFT ACCEPTANCE INDUCED BY MULTIPOTENT MESENCHYMAL STROMAL CELLS IN A RAT HEART TRANSPLANTATION MODEL . 76 Popp, Felix C., Eggenhofer, Elke, Slowik, Prezemyslaw, Renner, Philipp, Schlitt, Hans J., Piso, Pompiliu, Dahlke, Marc H. SUN - 366: EX VIVO CB EXPANSION WITHOUT INITIAL CD34 OR CD133 SELECTION: DYNAMIC IN-CULTURE HAEMATOPOIETIC STEM CELL SELECTION BY A CLINICAL LICENSED ANTI-CD52 MONOCLONAL ANTIBODY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 Feng, Qi, Lim, Kang Che, Sun, Li, Hwang, William Ying Khee SUN - 367: HESC INDUCED ARTERIOGENESIS AFTER INTRAARTERIAL BUT NOT INTRA-MUSCULAR INJECTION IN HIND LIMB ISCHEMIA MODEL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 Staudacher, Dawid, Sela, Yogev, Itskovitz-Eldor, Joseph, Flugelman, Moshe

STEM CELLS AND AGING . . . . . . . . . . . . . . . . . . . . . . . . 70SUN - 344: IMPAIRED SELF-RENEWAL AND DIFFERENTIATION OF NEURAL STEM CELLS INDUCED BY NITRIC OXIDE (NO) MEDIATED SIGNALING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Kim, Sun Jung, Lim, Myung sin, Lee, Bong Hee, Lee, Yong-Soon, Kang, Kyung-Sun SUN - 345: THREE-DIMENSIONAL SPATIAL MODEL OF THE TGFBETA SIGNALING PATHWAY AND ITS CROSSTALK WITH THE NOTCH SIGNALING PATHWAY . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 Arjunan, Satya Nanda Vel, Tomita, Masaru SUN - 346: PHYSICAL EXERCISE INCREASES THE NUMBER OF ENDOGENOUS NSCS IN AGED MICE . . . . . . . . . . . . . . . . . . . . . . 71 Blackmore, Daniel G., Large, Beatrice, Golmohammadi, Mohammad, Rietze, Rodney L. SUN - 347: THE ROLE OF STROMAL CELL NICHE INTERACTIONS WITH STEM AND PROGENITOR CELLS IN THE BONE MARROW AND THYMUS IN THE ESTABLISHMENT, MAINTENANCE, AGEING AND REGENERATION OF THE IMMUNE SYSTEM . . . . . . . . . . . . . 71 Chidgey, Ann, Hammett, Maree, Young, Lauren, Seach, Natalie, Ueno, Tomoo, Fletcher, Anne, Boyd, Richard

THERAPEUTIC APPLICATIONS CLINICAL AND PRE-CLINICAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71SUN - 348: INFUSION OF AUTOLOGOUS BONE MARROW DERIVED MONONUCLEAR CELLS IN HUMAN CIRRHOSIS: IMAGING AND BIOCHEMICAL EVIDENCE OF LIVER FUNCTION IMPROVEMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 Rezende, Guilherme F. M., Guaraldi, Bianca C., Fonseca, Lea Mirian B., Gutfilen, Bianca, Schmidt, Fernanda M. G., Resende, Clia Maria C., Coelho, Henrique Srgio M., Azevedo, Feliciano S., Maiolino, Angelo, Pedras, Paulo S. V., Cruz, Igor C., SUN - 349: REDUCTION OF LIVER FIBROSIS BY XENOGENEIC HUMAN UMBILICAL CORD BLOOD- AND ADIPOSE TISSUEDERIVED MESENCHYMAL STEM CELL WITHOUT IMMUNOSUPPRESSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 Jung, Ji-Won, Lee, Yeong-Geon, Sun, Bo, Lee, Yong-Soon, Kang, Kyung-Sun SUN - 350: PATHOLOGICAL MODELLING OF TYPE 1 MYOTONIC DYSTROPHY DISEASE BY USING MUTANT HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 Martinat, Cecile, Marteyn, Antoine, Sermon, Karin, Pitu, Genevive, Peschanski, Marc SUN - 351: FUNCTIONAL IMPROVEMENT BY HUMAN ES CELLDERIVED ENDOTHELIAL CELL TRANSPLANTATION IN A MOUSE MODEL OF HINDLIMB ISCHEMIA . . . . . . . . . . . . . . . . . . . . . . . . . 73 Moon, Sung Hwan, Cho, Seung-Woo, Lee, Soo Hong, Kang, Sun-Woong, Kim, Jumi, Lim, Jae Min, Kim, Hyo-Soo, Kim, Byung-Soo, Chung, Hyung-Min SUN - 352: HUMAN MESENCHYMAL STEM CELLS (MSC) CONTRIBUTE BY DISTANT EFFECT TO RESTORE THE HEPATIC INTEGRITY DISRUPTED AFTER IRRADIATION . . . . . . . . . . . . . . . . 73 Moubarak, Mouiseddine SUN - 353: HUMAN MESENCHYMAL STEM CELL EXPRESSED HLAG: ROLE IN MSC MEDIATED IMMUNOSUPPRESSIVE EFFECT. . . . 73 Nasef, Aisha A., Mathieu, Noelle, Chapel, Alain, Frick, Johanna, Franois, Sabine, Mazurier, Christelle, Boutarfa, Asma, Bouchet, Sandrine, Gorin, NClaude, Thierry, Dominique, Fouillard, Loc

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Table of ContentsSUN - 368: EARLY SYSTEMIC TRANSPLANTATION OF NEUROSPHERE-FORMING CELLS REDUCES CEREBRAL INFLAMMATION AFTER STROKE VIA MODULATION OF PERIPHERAL IMMUNE SYSTEMS . . . . . . . . . . . . . . . . . . . . . . . . . 77 Lee, Soon-Tae, Chu, Kon, Jung, Keun-Hwa, Park, Hee-Kwon, Kim, Manho, Roh, Jae-Kyu SUN - 369: POTENTIAL OF EMBRYONIC STEM CELL DERIVED CHONDROGENIC CELLS FOR TREATING DISCOGENIC DISEASE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Sheikh, Hormoz, Fecek, Christopher, Pasierb, Magdalena, Mariorana, Deanna, Didyuk, Oksana, Andrus, Lee, Kaceli, Milessa, Lobocki, Catherine, Buttry, Janelle, Hibbard, Nick, Tyranski, Kelli, Silberberg, Boris, Chaudhry, G. Rasul SUN - 371: ENHANCEMENT OF MUSCLE REPAIR BY HEMATOPOIETIC CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Long, Mike, Rossi, Fabio SUN - 372: ISOLATION AND CHARACTERIZATION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS DERIVED FROM BONE MARROW OF TYPE 1 DIABETES AND MULTIPLE SCLEROSIS PATIENTS BEFORE AND AFTER EXPOSURE TO HIGH-DOSE IMMUNOSUPPRESSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Malmegrim, Kelen Cristina Ribeiro, Prata, Karen Lima, Silva, Aline Cristina Garcia, Bolzoni, Rosane Maria Falasco, Palma, Patrcia Bonini Vianna, Solano, Karina Rosa, Orellana, Maristela Delgado, Zago, Marco Antonio, Covas, Dimas Tadeu, Voltarelli, Jlio SUN - 373: ISOLATION AND CHARACTERIZATION OF ENDOTHELIAL PROGENITOR CELLS FROM PERIPHERAL BLOOD OF TYPE II DIABETIC PATIENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Manochantr, Sirikul, Churdchomjan, Worachat, Kheolamai, Pakpoom, Tantrawatpan, Chairat, Issaragrisil, Surapol SUN - 374: THE EFFECT OF INTERFERON-BETA ON MURINE NEURAL STEM CELL SURVIVAL AND DIFFERENTIATION . . . . . . . 79 Mao-Draayer, Yang, Tobita, Mari, Eckenstein, Felix, Panitch, Hillel SUN - 375: PYNTTTTGT OLIGONUCLEOTIDES AS TOOLS IN TISSUE REPAIR PROCEDURES . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Montaner, Alejandro D., Hernando-Insa, Andrs, Elas, Fernanda, Coronel, Florencia, DeNichilo, Anala, Rodriguez, Juan, Fl, Juan, Lpez, Ricardo, Matskin, Bernardo, Chasseing, Alejandra, Villar, Marcelo, Zorzopulos, Jorge SUN - 376: THERAPEUTIC EFFECT OF PLACENTA-DERIVED MESENCHYMAL STEM CELLS IN CCL4-INDUCED LIVER CIRRHOSIS MODEL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Na, Kyu-hwan, Lee, Ran, Shin, Kyung-Sun, Ki, Ho-Yun, Lee, Hey-Jin, Cha, Kwang-Yul, Kim, Jae-Hwan, Chung, Hyung-Min, Lee, Min-Jae, Kim, Gi Jin SUN - 377: IMPROVED FUNCTIONAL OUTCOME WITH GRANULOCYTE COLONY STIMULATING FACTOR IN ACUTE ISCHEMIC STROKE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Rajappa, Sivakumar M. SUN - 378: DOUBLE KNOCKDOWN OF DIABETES RELATED GENES IN MOUSE ES CELLS AND THEIR DIFFERENTIATION INTO INSULIN-PRODUCING CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Saito, Mikako, Hayakawa, Aya, Yoda, Terumi, Tsuzuki, Takahiro, Matsuoka, Hideaki SUN - 379: STEM CELL TREATMENT AMELIORATES MUSCLE FUNCTION IN DYSTROPHIC DOGS . . . . . . . . . . . . . . . . . . . . . . . . 81 Sampaolesi, Maurilio, Cassano, Marco, Cossu, Giulio, Cusella, Gabriella, Tonlorenzi, Rossana, Perani, Laura, Crippa, Stefania SUN - 380: G-CSF ENHANCED PERIPHERAL BLOOD STEM CELLS FOR CARDIOVASCULAR DISORDERS A CLINICAL STUDY . . . . 81 Sankar, Madhu, Vaidyanathan, Karthik, Sekar, Prem, Jaiswal, Pramod, Thomas, Joy, Sankar, Jai, Cherian, Kotturathu M. SUN - 381: MULTIPOTENT ADULT PROGENITOR CELLS (MAPC) SUPPRESS LYMPHOCYTE PROLIFERATION IN VITRO AND PREVENT GRAFT VERSUS HOST DISEASE. . . . . . . . . . . . . . . . . . . . . . . . . . . 81 Kovacsovics-Bankowski, Magdalena, Streeter, Philip R., Mauch, Kelsey A., Vant Hof, Wouter J., Deans, Robert J., Maziarz, Richard T. SUN - 383: MACROPHAGE UPTAKE OF INTRACELLULAR EXOGENOUS CELL LABEL FROM STEM CELLS IMPLICATION FOR CELL TRANSPLANTATION AND CELLULAR IMAGING. . . . . . . . . . 81 Pawelczyk, Eddy, Arbab, Ali S., Frank, Joseph A. SUN - 384: STEM CELLS THERAPY FOR ACUTE AND CHRONIC STROKE PATIENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 Lin, Shinn-Zong, Shyu, Woei-Cherng, Li, Hung

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Table of ContentsCANCER STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . 85MON - 101: PRELIMINARY EVIDENCE FOR PROGENITOR/STEM CELLS IN HUMAN ENDOMETRIAL ADENOCARCINOMA . . . . . . . 85 Hubbard, Sonya, Chan, Rachel W.S., Gargett, Caroline E. MON - 102: HIGH-THROUGHPUT SCREENING FOR NOVEL COMPOUNDS SPECIFICALLY TOXIC TO HUMAN LEUKEMIC CELLS DERIVED FROM LINEAGE-DEPLETED CORD BLOOD CELLS . . . . . 85 McDermott, Sean, Datti, Alessandro, Dick, John E. MON - 103: ESTROGEN MEDIATED OCT-4 UP-REGULATION AND PROLIFERATION OF CANCER STEM CELL POPULATION IN ER+ HUMAN BREAST CANCER CELL LINES . . . . . . . . . . . . . . . . . . . . . 85 Jung, Ji-Won, Lee, Soo-Jin, Lee, Yong-Soon, Kang, Kyung-Sun MON - 104: GENE EXPRESSION PROFILING OF BRAIN CANCER STEM CELLS IDENTIFIES GENES CORRELATED WITH MALIGNANCY IN HUMAN ASTROCYTOMAS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Okamoto, Oswaldo K., Oba-Shinjo, Sueli M., Lopes, Luciana R., Marie, Suely K.N. MON - 105: PRE-LEUKEMIC AMPLIFICATION OF GRANULOCYTES BY ENFORCED EXPRESSION OF MEIS1 OR MEIS3 IN HEMATOPOIETIC STEM CELLS OF ICSBP-DEFICIENT MICE . . . . . . 86 Hara, Takahiko, Schwieger, Maike, Kazama, Ritsuko, Okamoto, Shiki, Stocking, Carol MON - 106: PREVENTION OF LUNG CANCER BY MOUSE EMBRYONIC STEM CELL VACCINATION . . . . . . . . . . . . . . . . . . . . 86 Mitchell, Robert A., Brewer, Bradley, Krishnan, Elangovan, Williams, Lisa, Gao, Xueshan, Janjua, Muhammad, Haribabu, Bodduluri, Eaton, John W. MON - 107: EMBRYONIC STEM CELLS AND EMBRYONAL TERATOCARCINOMA CELLS: SIGNAL PATHWAYS OF TGF SUPERFAMILY FACTORS AND DIFFERENTIATION POTENTIAL IN VITRO AND IN VIVO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 Gordeeva, Olga F., Krasnikova, Natalia, Nikonova, Tatyana, Golub, Alla, Lifantzeva, Nadia MON - 108: EVI-1 IS ESSENTIAL FOR PROLIFERATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS AND TRANSFORMED LEUKEMIC CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 Goyama, Susumu, Yamamoto, Go, Sato, Tomohiko, Ichikawa, Motoshi, Ogawa, Seishi, Chiba, Shigeru, Kurokawa, Mineo MON - 109: A NOVEL WAY TO ACTIVATE DORMANT MOUSE HEMATOPOIETIC STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 Essers, Marieke AG, Offner, Sandra, Aubry, Dominique, Waibler, Zoe, Kalinke, Ulrich, Duchosal, Michel, Trumpp, Andreas MON - 110: BIOLOGICAL AND GENETIC SIGNATURES OF METASTATIC CANCER STEM CELL. . . . . . . . . . . . . . . . . . . . . . . . . 87 Joo, Kyeung Min, Oh, Keunhee, Lee, Min Su, Choi, Jung Yun, Sohn, Yeo Won, Jang, Mi-Jeong, Lee, Young-Ju, Matthews, Clayton A., Bang, Sa-Ik, Lee, Dong-Sup, Nam, Do-Hyun, Park, Woong-Yang MON - 111: CXCR4 UP-REGULATION BY IMATINIB MESYLATE INDUCES CML CELL MIGRATION TO BONE MARROW STROMA AND PROMOTES SURVIVAL OF CHEMORESISTANT QUIESCENT CML CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 Konopleva, Marina, Tabe, Yoko, Jin, Linhua, Leysath, Clinton E., Kimura, Shinya, Kantarjian, Hagop, Andreeff, Michael MON - 112: REGULATION OF STEM CELL MARKERS IN HNSCC BY CIGARETTE SMOKE CONDENSATE . . . . . . . . . . . . . . . . . . . . . . . . 88 Lopez, Jay Patrick, An, Yi, Bae, Coney, Chang, Cathey, Yu, Andrew, Ongkeko, Weg M. MON - 113: IDENTIFICATION AND CHARACTERIZATION OF CD133+ HEPATOCELLULAR CARCINOMA CELLS AS CANCER STEM/PROGENITOR CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 Ma, Stephanie, Chan, Kwok Wah, Ng, Irene O., Zheng, Bo-Jian, Guan, XinYuan MON - 114: LOCALIZATION AND UTILITY OF CANDIDATE STEM CELL MARKERS- P63 AND P53 IN OCULAR SQUAMOUS CELL CARCINOMA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 Vemuganti, Geeta K., Manderwad, Guru Prasad, Bhaduri, Anirban, Kannabiran, Chitra, Honavar, Santosh G.

CHARACTERIZATIONS OF TISSUE SPECIFIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89MON - 115: ISOLATION, PURIFICATION AND IDENTIFICATION OF PANCREATIC STEM CELLS DERIVED FROM HUMAN FETAL ISLETLIKE CELL CLUSTERS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 Hai, Qiao, Ting, Zhao, Yun, Wang, Chunrong, Yang, Mei, Xiao, Zhongying, Dou MON - 116: MICRORNAS REGULATE EPITHELIAL TO MESENCHYMAL TRANSITION IN CLONALLY DERIVED HUMAN FETAL PANCREATIC ISLET CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . 90 Hardikar, Anandwardhan A., Joglekar, Mugdha V. MON - 117: DIRECT COMPARISON OF HUMAN MESENCHYMAL STEM CELLS DERIVED FROM ADIPOSE TISSUES AND BONE MARROW IN MEDIATING NEOVASCULARIZATION IN RESPONSE TO VASCULAR ISCHEMIA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 Kim, Hoe Kyu, Kim, Yeon Jeong, Cho, Hyun Hwa, Bae, Yong Chan, Suhe, Kuen Tak, Jung, Jin Sup MON - 118: A POSSIBLE MELANOCYTIC PRECURSOR CELLS DERIVED FROM HUMAN MESENCHYMAL STEM CELLS WITH PHORBOL 12-MYRISTATE 13-ACETATE (PMA)-FREE HUMAN MELANOCYTE GROWTH SUPPLEMENTS, STEM CELL FACTOR, ENDOTHELIN-1, AND FORSKOLIN. . . . . . . . . . . . . . . . . . . . . . . . . 90 Kwon, Soo Mee, Jeon, Songhee, Kim, Ji Young, Lee, Ai-Young MON - 119: CHANGES IN SURFACE MARKERS FOR HUMAN MESENCHYMAL STEM CELLS DURING CHONDROGENIC DIFFERENTIATION IN VITRO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Lee, Hyun Jung, Choi, Byung Hyune, Min, Byoung-Hyun, Park, So Ra MON - 120: EXPRESSION OF STEMNESS TRANSCRIPTS DOES NOT PREDICT STEM CELL ACTIVITY OF HUMAN MESENCHYMAL CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Oostendorp, Robert A.J., Kaltz, Nikolas, Riminucci, Mara, Charbord, Pierre, Bianco, Paolo, Peschel, Christian, Peschel, Christian MON - 121: ISOLATION AND CHARACTERIZATION OF ABCG2+/CD90+ MESENCHYMAL PROGENITOR CELLS FROM CHORIONIC VILLI OF HUMAN PLACENTA . . . . . . . . . . . . . . . . . . . 91 Lin, Abby H.C., Liu, Gin-Mol, Huang, Lynn L.H. MON - 122: PRODUCTION OF INSULIN BY ISLET-LIKE CELLS DIFFERENTIATED FROM HUMAN BONE MARROW MESENCHYMAL STEM CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92 Zhang, Yihua, Dou, Zhongying, Wang, Huayan, Zheng, Xibang, Hua, Jinlian, Yang, Chunrong, Gao, Zhimin, Lei, Anmin, Wang, Yun, Zhao, Ting, Qiao, Hai MON - 123: EFFECTS OF IN VITRO INDUCTION TIME OF 5AZACYTIDINE ON PROLIFERATION AND TRANS-DIFFERENTIATION OF HUMAN BONE MARROW MESENCHYMAL STEM CELLS INTO CARDIOMYOCYTE-LIKE CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . 92 Zhang, Yihua, Dou, Zhongying, Wang, Huayan, Zheng, Xibang, Hua, Jinlian, Yang, Chunrong, Gao, Zhimin, Lei, Anmin, Zhao, Ting MON - 124: DIFFERENTIATION OF HUMAN MARROW MESENCHYMAL STEM CELLS INTO NEUROCYTES . . . . . . . . . . . . 92 Zhang, Yihua, Dou, Zhongying, Wang, Huayan, Shen, Wenzheng, Hua, Jinlian, Yang, Chunrong, Gao, Zhimin, Lei, Anmin, Li, Yong MON - 125: ISOLATION AND CHARACTERIZATION OF LIVER STEM CELLS FROM FETAL AND ADULT MOUSE . . . . . . . . . . . . . . . . . . . 93 Tanaka, Minoru, Okabe, Mayuko, Suzuki, Kaori, Kawamura, Yuko, Miyajima, Atsushi

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Table of ContentsMON - 126: P53 TUMOR SUPPRESSOR REGULATES HUMAN HEMATOPOIETIC STEM CELLS (HSCS) SELF-RENEWAL AND SURVIVAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 Milyavsky, Michael, Gan, Olga I., Notta, Faiyaz, Lechman, Eric, Dick, John E. MON - 127: N-GLYCOSYLATION OF HUMAN HEMATOPOIETIC CD133+ CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 Hemmoranta, Heidi, Satomaa, Tero, Blomqvist, Maria, Heiskanen, Annamari, Aitio, Olli, Saarinen, Juhani, Natunen, Jari, Partanen, Jukka, Laine, Jarmo, Jaatinen, Taina MON - 128: IN VITRO HEPATIC DIFFERENTIATION OF MULTIPOTENT CELLS DERIVED FROM HUMAN PLACENTA AND UMBILICAL CORD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 Huang, Hsing-I, Chien, Chih-Cheng, Lai, Tsung-Hsuan, Yen, Betty Linju, Chen, Yao-Chang, Su, Li-Chiu MON - 129: INHIBITION OF ENDOGENOUS MYD88 SIGNALING SUPPRESSES PROLIFERATION AND DIFFERENTIATION IN HUMAN ADIPOSE DERIVED STROMAL CELLS . . . . . . . . . . . . . . . . . . . . . . 94 Joo, Hye Jun, Cho, Hyun Hwa, Jung, Jin Sup MON - 130: GENE EXPRESSION PROFILING OF HUMAN BONE MARROW STEM CELLS WITH VARIOUS PASSAGES . . . . . . . . . . . 94 Jung, Kyoung Hwa, Park, Kyoung Sun, Kim, Kyoung Suk, Choi, Mi Ran, Park, Ji-Yoon, Kim, Seung Hyun, Chai, Young Gyu MON - 131: GENE EXPRESSION PROFILING OF HUMAN NEURAL STEM/PROGENITOR CELLS AND ANALYSIS OF GENES INVOLVED IN DIFFERENTIATION. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 Kanemura, Yonehiro, Shofuda, Tomoko, Yamamoto, Atsuyo, Mori, Hideki, Okano, Hideyuki, Yamasaki, Mami MON - 132: SURFACE MARKER EXPRESSION AND DIFFERENTIATION CAPACITY OF HUMAN DENTAL STEM CELLS FROM IMPACTED THIRD MOLARS . . . . . . . . . . . . . . . . . . . . . . . . 95 Lindroos, Bettina I., Miettinen, Susanna, Suuronen, Riitta MON - 133: GROWTH AND PHENOTYPIC CHARACTERISTICS OF HUMAN DENTAL PULP STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . 95 Karbanova, Jana, Soukup, Tomas, Mokry, Jaroslav, Pytlik, Robert, Micuda, Stanislav, Suchanek, Jakub, Ivancakova, Romana, Kucerova, Lenka MON - 134: HUMAN BREAST STEM CELL TRANSFORMATION AND INVASIVENESS IS MEDIATED BY UP-REGULATION OF IL-8 THROUGH A TWIST AND NFKB TRANSCRIPTION FACTOR COMPLEX. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 Kendall, Stephen E., Covarrubias, Maricela, Tran, Christine, Leigh, Victoria, Aboody, Karen, Glackin, Carlotta MON - 135: TOWARDS THE IDENTIFICATION OF HUMAN EMBRYONIC STEM CELL LINES SUITABLE FOR CELL THERAPY IN PARKINSONS DISEASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96 Kim, Hyesoo, Lee, Gabsang, Studer, Lorenz MON - 136: EXPRESSION OF NEURAL PROTEINS IN THE SPHEREFORMING FIBROBLAST CELLS DERIVED FROM DERMIS OF HUMAN FORESKIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96 Kim, Jong Bin, Lee, Kyung-Min, Ko, Eunyoung, Lee, Jeong Eon, Shin, Incheol, Kim, Sangmin, Han, Wonshik, Noh, Dong-Young MON - 137: ROLE OF CD9 IN THE FUNCTION OF HUMAN ADIPOSE TISSUE STROMAL CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 Kim, Yeon Jeong, Yu, Ji Min, Joo, Hye Jun, Kim, Hoe Kyu, Cho, Hyun Hwa, Bae, Yong Chan, Jung, Jin Sup MON - 138: HUMAN HEART-DERIVED STEM CELL ANTIGEN-1 POSITIVE CELLS DIFFERENTIATE INTO CARDIAC DERIVED CELLTYPES IN VITRO. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 Smits, Anke, Sluijter, Joost, de Boer, Teun, van Laake, Linda, van Veen, Toon, van der Heyden, Marcel, Korfage, Tom, Metz, Corina, Ramjankhan, Faiz, Doevendans, Pieter, Goumans, Marie-Jos MON - 139: HUMAN HAIR FOLLICLE CELLS WITH THE CELL SURFACE MARKER CD34 CAN REGENERATE NEW MOUSE HAIR FOLLICLES AND LOCATED IN THE OUTER ROOT SHEATH OF IMMUNODEFICIENT NUDE MICE . . . . . . . . . . . . . . . . . . . . . . . . . 97 Lee, Sung-Hoon, Chung, Mi-Kyung, Sohn, Yong-Jin, Ra, Jung-Chan, Kang, Kyung-Sun MON - 140: ISOLATION AND CHARACTERIZATION OF MOUSE ADULT STEM CELLS FROM KIDNEY . . . . . . . . . . . . . . . . . . . . . . . 97 Gheisari, Yousof, Soleimani, Masoud, Zeinali, Sirous, Arefian, Ehsan, Nikougoftar Zarif, Mahin MON - 141: RETINAL PHOTORECEPTOR PROPERTIES OF CRX/NRLINDUCTED MOUSE IRIS-DERIVED CELLS . . . . . . . . . . . . . . . . . . . 98 Hirami, Yasuhiko, Akimoto, Masayuki, Mandai, Michiko, Takahashi, Masayo, Yoshimura, Nagahisa MON - 142: STUDYING MOUSE HEMANGIOBLAST-DERIVED COLONIES TO UNDERSTAND THE ESTABLISHMENT OF THE HEMATOPOIETIC PROGRAM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 Huber, Tara L., Keller, Gordon MON - 143: AML1/RUNX1 NEGATIVELY REGULATES QUIESCENT HEMATOPOIETIC STEM CELLS IN ADULT MICE . . . . . . . . . . . . . . 98 Ichikawa, Motoshi, Asai, Takashi, Nakagawa, Masahiro, Kawazu, Masahito, Goyama, Susumu, Takeshita, Masataka, Chiba, Shigeru, Ogawa, Seishi, Kurokawa, Mineo MON - 144: PHENOTYPIC CHARACTERISATION OF MOUSE CARDIAC STEM AND PROGENITOR CELLS . . . . . . . . . . . . . . . . . . 99 Li, Joan, Chandrakanthan, Vashetharan, Heffernan, Corey, Harvey, Richard P. MON - 145: MOUSE SALIVARY GLAND FUNCTION RESCUE AFTER STEM CELL TRANSPLANTATION IN IRRADIATED GLANDS. . . . . . 99 Lombaert, Isabelle M.A., Brunsting, Jeanette F., Wierenga, Pieter K., Kok, Tineke, Visser, Willy H., Kampinga, Harm H., de Haan, Gerald, Coppes, Rob P. MON - 146: GLYCEROPHOSPHOLIPID SIGNATURE IN ADULT MOUSE RETINAL STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 Li, Jianxue, Cui, Zheng, Zhao, Sheyun, Sidman, Richard L. MON - 147: MOUSE AND RAT MESENCHYMAL STEM CELL GROWTH OPTIMIZATION, PHENOTYPE AND FUNCTION . . . . . . 100 Cook, Matthew M., Barlow, Sarah, Chatterjee, Konika, Brooke, Gary, Pain, Scott, Atkinson, Kerry MON - 148: FUNCTIONAL INHIBITION OF NUCLEOSTEMIN A COORDINATOR OF SELF-RENEWAL IN RAT BONE MARROW DERIVED MESENCHYMAL STEM CELLS BY RNA INTERFERENCE STRATEGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 Jafarnejad Shourkaei, Seyed Mehdi, Nikpour, Parvaneh, Matin, Maryam, Mowla, Seyed Javad MON - 149: NEURAL DIFFERENTIATION POTENTIALS OF RAT AMNIOTIC CELLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 Komuro, Hiroaki, Shinya, Miki, Saihara, Ryoko, Urita, Yasuhisa, Kaneko, Setsuko, Kaneko, Michio, Liu, Ying MON - 150: GENETIC MANIPULATION OF MURINE RETINAL STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 Giannelli, Serena G., Gismano, Elena, Andreazzoli, Massimiliano, Rama, Paolo, Broccoli, Vania MON - 151: PROSPECTIVE ISOLATION OF COMMITTED ADIPOGENIC PROGENITOR CELLS FROM MURINE ADULT SKELETAL MUSCLE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Joe, Aaron WB, Wang, Joy, So, Leslie, Yi, Lin, Rossi, Fabio MON - 152: REDUCTION OF MULTIPOTENT NEURAL STEM/PRECURSOR CELLS AND INCREASE OF NEURONAL PROGENITORS BY WNT SIGNALING IN THE MURINE EMBRYONIC NEOCORTICAL CULTURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Kuwahara, Atsushi, Hirabayashi, Yusuke, Masuyama, Norihisa, Gotoh, Yukiko

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Table of ContentsMON - 153: MOLECULAR PROFILE OF DERMAL CANDIDATE MSC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Blashki, Daniel, Brouard, Nathalie, Simmons, Paul J. MON - 154: THE ENDOTHELIAL PROGENITOR CELL: CHARACTERIZATION AND CONTRIBUTION TO VASCULARIZATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 Heine, Heather L., Rossi, Fabio M., McManus, Bruce M. MON - 155: CULTURED BOVINE SPERMATOGONIAL STEM CELLS: PROPAGATION RATE AND EXPRESSION OF STEM CELL MARKERS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 Hope, Michelle, Kelley, Bronwyn, Stockwell, Sally, Brownlee, Alan MON - 156: DEFINING A MOLECULAR SELF-RENEWAL SIGNATURE FOR HEMATOPOIETIC STEM CELLS . . . . . . . . . . . . . . . . . . . . . . . 102 Klug, Christopher, Swindle, Scott MON - 157: ESSENTIAL ROLE OF TRANSCRIPTION ELONGATION FACTOR S-II/TFIIS IN DEFINITIVE HEMATOPOIESIS . . . . . . . . . . 102 Ito, Takahiro, Arimitsu, Nagisa, Takeuchi, Masaki, Mizuguchi, Asami, Takeuchi, Kazusane, Miyajima, Atsushi, Sekimizu, Kazuhisa MON - 158: THE ROLE OF SIGNALING FROM CAMP TO MAPK IN THE REGULATION OF BONE MARROW HEMATOPOIETIC STEM CELLS GROWTH BY -FETOPROTEIN. . . . . . . . . . . . . . . . . . . . . . 103 Rybakova, Tatyana M., Belyaev, Nikolay N., Bogdanov, Andrey Yu MON - 159: CA2+ INFLUX INVOLVES IN SIGNAL TRANSMISSION OF A-FETOPROTEIN GROWTH REGULATORY STIMULUS ON BONE MARROW HEMATOPOIETIC STEM CELLS . . . . . . . . . . . . . . . . . . 103 Rybakova, Tatyana M., Belyaev, Nikolay N., Bogdanov, Andrey Yu MON - 160: WORKING TOWARDS A STEM CELL THERAPY FOR TYPE 1 DIABETES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 Jiang, Fang-Xu MON - 161: DNA IS PARTITIONED ASYMMETRICALLY IN THE GERMLINE STEM CELLS OF DROSOPHILA MELANOGASTER . . . 104 Karpowicz, Phillip, Pellikka, Milena, Godt, Dorothea, Tepass, Ulrich, van der Kooy, Derek MON - 162: REGULATION OF NEURAL STEM CELL COMMITMENT, SELF-RENEWAL AND DIFFERENTIATION BY SHP2 TYROSINE PHOSPHATASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 Ke, Yuehai, Hagihara, Kazuki, Wu, Dongmei, Pang, Yuhong, Feng, GenSheng MON - 163: ISOLATION OF HEPATIC STEM CELLS USING A NOVEL SURFACE ANTIGEN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 Konishi, Sayuri, Yasuchika, Kentaro, Machimoto, Takafumi, Ishii, Takamichi, Kamo, Naoko, Komori, Junji, Shimoda, Masayuki, Babazono, Yutaka, Fukumitu, Tsurugi, Uemoto, Shinji, Ikai, Iwao MON - 164: POTENTIAL THERAPEUTIC CLUE OF SKIN-DERIVED PROGENITOR CELLS FOLLOWING CYTOKINE-MEDIATED SIGNAL OVEREXPRESSED IN INJURED SPINAL CORD . . . . . . . . . . . . . . . 104 Lee, Mi R., Kim, Yeo W., Kang, Soo K. MON - 165: UMBILICAL CORD LINING MESENCHYMAL CELLS SUPPRESS IN VITRO MIXED LYMPHOCYTE REACTION. . . . . . . . 105 Phan, T.T., Zhou, Yue, Gan, S.U., Masilamani, J., Lim, I.J., Calne, Roy, Lee, K.O., Macary, P.A. MON - 166: THE ROLE OF POTASSIUM CHANNELS IN NEURONAL DIFFERENTIATION OF STEM CELLS FROM UMBILIBAL CORD . . 105 Leming, Matthew T., Hoynowski, Steve, Fry, Madeline, Mitchell, Kathy MON - 167: UMBILICAL CORD PERIVASCULAR CELLS ARE IMMUNOPRIVILEGED AND IMMUNOMODULATORY . . . . . . . . . 105 Ennis, Jane, Gotherstrom, Cecilia, Le Blanc, Katarina, Davies, John E. MON - 168: OCT4 HAS NO ROLE IN SELF-RENEWAL OF SOMATIC STEM CELLS, TISSUE HOMEOSTASIS, OR REGENERATION. . . . . 106 Lengner, Christopher J., Jaenisch, Rudolf MON - 169: ABERRANT KRUPPEL-LIKE FACTOR 4 EXPRESSION CAUSES PROLIFERATION DEFECT IN PATCHED1-/- NEURAL CREST CELLS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 Ngan, Elly SW, Poon, Tracy HC, Sham, Mai-Har, Hui, Chi-Chung, Wainwright, Brandon, Tam, Paul KH, Lui, Vincent CH MON - 170: THE SCL TRANSCRIPTIONAL NETWORK AND THE BMP SIGNALING PATHWAY INTERACT TO REGULATE RUNX1 ACTIVITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 Pimanda, John E., Donaldson, Ian, de Bruijn, Marella, Kinston, Sarah, Knezevic, Kathy, Tannahill, David, Green, Anthony R., Gttgens, Berthold MON - 171: OSTEOCLAST PRECURSORS CAN BE GENERATED FROM CD34-LIN-CD45- CELLS ISOLATED FROM PERIPHERAL BLOOD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 Rofani, Cristina, Ciraci, Elisa, Scianaro, Roberta, Bottazzo, Gianfranco, Berardi, Anna C.

CONTROLLED DIFFERENTIATION TO ECTODERMAL DERIVATIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107MON - 172: WNTS ARE KEY REGULATORS OF SURVIVAL, EXPANSION AND MAINTENANCE OF NEURAL PROGENITORS DERIVED FROM HUMAN EMBRYONIC STEM CELLS. . . . . . . . . . 107 Dottori, Mirella, Davidson, Kathryn C., Jamshidi, Pegah, Daly, Rachel, Hearn, Milton TW, Pera, Martin F. MON - 173: HUMAN ESC DERIVED NEURAL ROSETTES REPRESENT A NOVEL UNIVERSAL NEURAL STEM CELL STAGE . . . . . . . . . . 107 Elkabetz, Yechiel, Socci, Nicholas D., Studer, Lorenz MON - 174: DIRECT DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO NEURAL PROGENITORS USING FEEDER AND ANIMAL FREE CONDITIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 Erceg, Slaven, Stojkovic, Petra, Ronaghi, Mohammad, Stojkovic, Miodrag MON - 175: IDENTIFICATION AND FUNCTIONAL VALIDATION OF MICRORNAS DURING NEUROGENESIS FROM HESC . . . . . . . . . 108 Ge, Weihong, Wu, Hao, He, Fei, Sun, Yi Eve MON - 176: NEURAL PROGENITORS FROM FEEDER-FREE ADHERENT HUMAN EMBRYONIC STEM CELLS CAN GENERATE NEURONS AND CELLS OF GLIAL LINEAGES . . . . . . . . . . . . . . . . 108 Dhara, Sujoy K., Hasneen, Kowser, Stice, Steven L. MON - 177: GENETIC ENGINEERING OF MOUSE AND HUMAN EMBRYONIC STEM CELLS TO DIRECT DIFFERENTIATION INTO MESENCEPHALIC DOPAMINE NEURONS . . . . . . . . . . . . . . . . . . 108 Denham, Mark, Bjrklund, Anders MON - 178: NEURAL DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS UPON EXPOSURE TO SOLUBLE FACTORS FROM MOUSE NEUROSPHERE CULTURES . . . . . . . . . . . . . . . . . . . . . . . 109 Gan, Hui Theng, Ramachandran, Ashray, Ahmed, Sohail MON - 179: BASIC FIBROBLAST GROWTH FACTOR EFFECTS IN MOUSE BONE MARROW STROMAL CELLS NEUROGENESIS INDUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 Hai Jie, Yang, Yin Yan, Xia, King Shung, Khoo, Zhi Wei, Feng MON - 180: MOUSE EMBRYONIC STEM CELL DERIVED GABAERGIC NEURONS ARE A PHARMACOLOGICALLY HETEROGENEOUS POPULATION . . . . . . . . . . . . . . . . . . . . . . . . . 109 Khaira, Simer K., Pouton, Colin W., Haynes, John M. MON - 181: NEURALLY INDUCED MESENCHYMAL STEM CELLS SURVIVE, GENERATE NEURONAL AND GLIAL CELLS, AND INTEGRATE INTO HOST NEURAL CIRCUITRIES AFTER TRANSPLANTATION INTO INTACT SPINAL CORD OF RATS . . . . 109 Alexanian, Arshak R., Stadig, Christy S., Syring, Mara B.,