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Page 1: 12web.sapmed.ac.jp/im2/uploadimages/filefile/7c6215be87cbd4a33756d09... · 2 4579867! Roles of phospho-GSK-3! in myocardial protection afforded by activation of the mitochondrial

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4579867!

Roles of phospho-GSK-3! in myocardial protection afforded by activation of the mitochondrial KATP channel.

Terashima Y, Sato T, Yano T, Maas O, Itoh T, Miki T, Tanno M, Kuno A, Shimamoto K, Miura T.

J Mol Cell Cardiol 49:762-770, 2010

Cytoskeletal proteins: hidden targets of cytoprotective signaling? Miura T.

Circ J 74:2295-2296, 2010

Mitochondrial kinase signalling pathways in myocardial protection from ischaemia/reperfusion-induced necrosis.

Miura T, Tanno M, Sato T.

Cardiovasc Res 88:7-15, 2010

Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection. Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K, Miura T.

Hypertension: Nov8, 2010 (Epub)

Mitochondria and GSK-3beta in cardioprotection against ischemia/reperfusion injury.

Miura T, Tanno M.

Cardiovasc Drugs Ther 24:255-263, 2010

Role of the gap junction in ischemic preconditioning in the heart. Miura T, Miki T, Yano T.

Am J Physiol Heart Circ Physiol 298:H1115-1125, 2010

Epicardium and pericardium:a joint force for infarct repair? Miura T.

J Mol Cell Cardiol 48:579-581, 2010

Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of

cardioprotective signaling in diabetic hearts. Hotta H, Miura T, Miki T, Togashi N, Maeda T, Kim SJ, Tanno M, Yano T, Kuno A, Itoh T, Satoh T, Terashima

Y, Ishikawa S, Shimamoto K.

Circ Res 106:129-132, 2010

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3

Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure.

Tanno M, Kuno A, Yano T, Miura T, Hisahara S, Ishikawa S, Shimamoto K, Horio Y.

J Biol Chem 285:8375-8382, 2010

Left ventricular hypertrophy causes different changes in longitudinal, radial, and circumferential mechanics in patients with hypertension:A two-dimensional speckle tracking study. Kouzu H, Yuda S, Muranaka A, Doi T, Yamamoto H, Shimoshige S, Hase M, Hashimoto A, Saitoh S, Tsuchihashi K, Miura T, Watanabe N, Shimamoto K. J Am Soc Echocardiogr: Dec 10, 2010 (Epub)

Delayed visceral bleeding from liver injury after cardiopulmonary resuscitation. Kouzu H, Hase M, Kokubu N, Nishida J, Kawamukai M, Usami Y, Hirokawa N, Meguro M, Tsuchihashi K,

Miura T, Asai Y, Shimamoto K.

J Emerg Med: Sep16, 2010 (Epub)

Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A review of the

Japanese literature. Morimura N, Sakamoto T, Nagao K, Asai Y, Yokota H, Tahara Y, Atsumi T, Nara S, Hase M.

Resuscitation: Oct 8, 2010 (Epub)

Associations of metabolic factors!especially serum retinolbinding protein 4 (RBP4)!with blood pressure in Japanese: the Tanno-Sobetsu study.

Chiba M!Saitoh S!Ohnishi H!Akasaka H!Mitsumata K!Furukawa T!Shimamoto K.

Endocr J 57:811-817, 2010

Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells. Sugino T, Maruyama M, Tanno M, Kuno A, Houkin K, Horio Y.

FEBS Lett 584:2821-2826, 2010

Impaired cardiac sympathetic innervation and myocardial perfusion are related to lethal arrhythmia:

quantification of cardiac tracers in patients with ICDs. Nishisato K, Hashimoto A, Nakata T, Doi T, Yamamoto H, Nagahara D, Shimoshige S, Yuda S, Tsuchihashi K

and Shimamoto K.

J Nucl Med 51:1241–1249, 2010

Prognostic value of gated myocardial perfusion imaging for asymptomatic patients with type 2 diabetes: the J-ACCESS 2 investigation. Yamasaki Y, Nakajima K, Kusuoka H, Izumi T, Kashiwagi A, Kawamori R, Shimamoto K, Yamada N, Nishimura T Diabetes Care 33:2320-2326, 2010

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4

Obesity as a risk factor for coronary events in Japanese patients with hypercholesterolemia on low-dose simvastatin therapy Saito Y, Kita T, Mabuchi H, Matsuzaki M, Matsuzawa Y, Nakaya N, Oikawa S, Sasaki J, Shimamoto K, Itakura H. J Atheroscler Thromb 17:270-277, 2010

Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese.

Shimaoka I, Kamide K, Ohishi M, Katsuya T, Akasaka H, Saitoh S, Sugimoto K, Oguro R, Congrains A,

Fujisawa T, Shimamoto K, Ogihara T, Rakugi H.

Hypertens Res 33:214-218, 2010

Integration of data from NIPPON DATA80/90 and National Nutrition Survey in Japan: for cohort studies of representative Japanese on Nutrition.

Okuda N, Miura K, Yoshita K, Matsumura Y, Okayama A, Nakamura Y, Okamura T, Saitoh S, Sakata K, Ojima

T, Turin UC, Ueshima H.

J Epidemiology 20:S506-514, 2010

Total energy intake and intake major nutrition by body mass index in Japan: NIPPON DATA80 and NIPPON DATA90.

Yoshita K, Arai Y, Nozaki M, Komatsu K, Ohinishi H, Saitoh S, Miura K.

J Epidemiology 20:S515-523, 2010

Variation in OSBPL 10 is associated with dyslipidemia.

Koriyama H!Nakagami H!Katsuya T!Akasaka H!Saitoh S!Shimamoto K!Ogihara T!Kaneda Y!

Morishita R!Rakugi H.

Hypertens Res 33:511-514, 2010

Relation of polyunsaturated to saturated fatty acid ratio to cardiovascular risk and metabolic syndrome in Japanese: The INTERLIPID study.

Guo Z!Miura K!Chowdhury TT!Hozawa A!Okuda N!Okamura T!Saitoh S!Sakata K!Nakagawa H!

Okayama A Yoshita K!Kadowaki T!Choudhury!Nakamura Y!Rodriguez BL!Curb JD!Elliott P!

Stamler J!Ueshima H.

J Atheroscler Thromb 17:7 77-784, 2010

Double-stranded RNA dependent protein kinase links pathogen sensing with stress and metabolic

homeostasis. Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS.

Cell 140:338-348, 2010

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Overview of regular dialysis treatment in Japan (as of 31 December 2008) Nakai S, Suzuki K, Masakane I, Wada A, Itami N, Ogata S, Kimata N, Shigematsu T, Shinoda T, Syouji T,

Taniguchi M, Tsuchida K, Nakamoto H, Nishi S, Nishi H, Hashimoto S, Hasegawa T, Hanafusa N, Hamano T,

Fujii N, Marubayashi S, Morita O, Yamagata K, Wakai K, Watanabe Y, Iseki K, Tsubakihara Y.

Ther Apher Dial 14:505-40, 2010

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59th Annual Scientific Session of the American College of Cardiology, Atlanta , USA, March 14-16, 2010

Role of left atrial reservoir dysfunction in pathophysiology of diastolic heart failure Kouzu H, Yuda S, Nishida J, Funayama N, Mochizuki A, Ichimura M, Doi T, Yamamoto H, Muranaka A,

Kokubu N, Fujii N, Shimoshige S, Hase M, Hashimoto A, Tsuchihashi K, Watanabe N, Shimamoto K.

Prognostic implications of cardiac sympathetic innervation assessed by MIBG in heart failure patients

with preserved left ventricular ejection fraction Doi T, Funayama N, Nishida J, Mochizuki A, Kouzu H, Fujii N, Wakabayashi T, Yuda S, Hase M, Hashimoto A,

Tsuchihashi K, Shimamoto K, Nakata T.

Short- and long-term prognostic impacts of metabolic syndrome and chronic kidney disease in patients after acute myocardial infarction

Kokubu N, Otsuka Y, Yagi N, Kasahara Y, Kataoka Y, Goto Y, Nonogi H.

20th World Congress of the International Society for Heart Research, Kyoto, Japan, May 13-16, 2010

Connexin43-dependent mitochondrial GSK-3" phosphorylation in protection of cardiomyocyte against necrosis Ishikawa S, Miki T, Tanno M, Miura T.

Enhancement of cyclophilin-D-ANT interaction upon reperfusion in hypertensive hypertrophied hearts: a target of cardioprotection against ischemia/reperfusion injury Yano T, Tanno M, Itoh T, Miura T.

Role of GSK-3" in negative regulation of the mPTPs by the mitochondrial KATP channel Itoh T, Terashima Y, Miki T, Miura T, Shimamoto K.

Mitochondria is a critical compartment for phospho-GSK-3" to afford cytoprotection against ischemia/reperfusion injury

Sato T, Miura T, Tanno M, Miki T, Takada A, Itoh T, Shimamoto K.

Glycogen synthase kinase-3" as a therapeutic target for cardiomyocyte protection Miura T, Miki T, Shimamoto K.

The 14th International Congress of Endocrinology, Kyoto, Japan, March 26-30, 2010

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Epidemiological aspects of diabetes and metabolic syndrome in Japanese general population

Saitoh S, Shimamoto K.

A case of gastrointestinal amyloidosis showing persistent hypocalcemia due to malabsorption of

magnesium Yamashita T, Tanaka M, Yoshida H, Murase H, Yamamoto S, Okazaki Y, Moniwa N, Togashi N,

Hyakukoku M, Furuhashi M, Shimamoto K.

ISN Nexus, Kyoto, Japan, April 15-18, 2010 Kidney in patients with cardiorenal syndrome is disturbed by venous congestion and oxidative stress Yoshida H, Tanaka M, Togashi N, Ito Y, Yokoyama Y, Ishimura S, Ota H, Moniwa N, Hyakukoku M,

Furuhashi M, Shimamoto K.

21st Annual Scientific Session of the American Society of Echocardiography, San Diego, USA, June 12-15, 2010 Hyperinsulinemia is associated with prolonged intra-atrial electromechanical delay in healthy overweight subjects

Muranaka A, Yuda S, Yamamoto H, Kouzu H, Doi T, Akasaka H, Ohnishi H, Shimoshige S, Hashimoto A,

Saitoh S, Nakata T, Tsuchihashi K, Watanabe N, Shimamoto K.

Quantitative measurement of circumferential carotid arterial strain by two-dimensional speckle tracking imaging in healthy subjects Yuda S, Kaneko R, Muranaka A, Hashimoto A, Tsuchihashi K, Watanabe N, Shimamoto K.

22nd Scientific Meeting of Transcatheter Cardiovascular Therapeutics, Washington DC, USA, September 21-25, 2010 Prognostic impacts of body mass index in patients after acute myocardial infarction - inverse J-curve phenomenon of mortality

Kokubu N, Otsuka Y, Yagi N, Taniguchi T, Kasahara Y, Kataoka Y, Miura T, Nonogi H.

14th International SHR Symposium, 6th International Congress of Pathophysiology, Montréal, Canada, September 22-25, 2010 Effects of angiotensin (1-7) on insulin resistance and hypertension induced by angiotensin II stimulation in

prepuberty Yoshida H, Togashi N, Shimamoto K.

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The 23rd Scientific Meeting of the International Society of Hypertension, Vancouver, Canada, September 26-30, 2010 Population science symposium Multiple risk factors in development of cardiovascular disease: A global perspective metabolic syndrome and hypertension in Japan - The Tanno Sobetsu Study - Shimamoto K. Angiotensin II stimulation in prepuberty induces sustained insulin resistance and hypertension via

continuously upregulated Rac-1, oxidative stress, and inflammatory cytokines Yamashita T, Togashi N, Okazaki Y, Ohta H, Ishimura S, Yokoyama Y, Tanaka M, Hyakukoku M, Yoshida H,

Shimamoto K.

Usefulness of the combination of abdominal obesity and high-sensitivity C-reactive protein for prediction of future occurrence of hypertension - the Tanno and Sobetsu Study -

Ohnishi H, Saitoh S, Akasaka H, Mitsumata K, Chiba M, Furugen M, Furukawa T, Mori M, Shimamoto K.

The association between blood pressure and glucagon-like peptide-1 concentration in a Japanese

population - The Tanno and Sobetsu Study - Akasaka H, Saitoh S, Ohnishi H, Mitsumata K, Chiba M, Furukawa T, Shimamoto K.

Optimal target blood pressure for elderly hypertensive patients Rakugi H, Ogihara T, Saruta T, Matsuoka H, Shimamoto K, Shimada K, Imai Y, Kikuchi K, Ito S, Eto T, Kimura G, Imaizumi T, Takishita S, Ueshima H, the VALISH Study Group Gene polymorphisms of FTO are partially associated with future blood pressure elevation in Japanese Shimaoka I, Kamide K, Katsuya T, Akasaka H, Saitoh S, Sugimoro K, Oguro R, Congrains A, Ohishi M, Shimamoto K, Ogihara T, Rakugi H

83rd Scientific Sessions of American Heart Association, Resuscitation Science Symposium, Chicago, USA, November 12-13, 2010 Impact of rewarming speed differences on outcome of therapeutic hypothermia in out-of-hospital cardiac arrest:An analysis in J-Pulse Hypo-registry, a multicenter hypothermia registry in Japan Kokubu N, Hase H, Tsuchihashi K, Nishida J, Muranaka A, Kouzu H, Miura T, Asai Y, Yonemoto N,

Yokoyama H, Nagao K, Nonogi H.

Prognostic significance of the combination of percutaneous cardiopulmonary assisted devices with mild

hypothermia in patients with out-of-hospital cardiac arrest:Insights from J-Pulse Hypo-registry Kokubu N, Yokoyama H, Yagi N, Hase M, Tsuchihashi K, Miura T, Yonemoto N, Nagao K, Nonogi H.

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83rd Scientific Sessions of American Heart Association, Chicago, USA, November 13-17, 2010 Activation of Sirt1 suppresses hypertrophic response of cardiomyocytes by inhibition of H3K9 acetylation

via proteasome-mediated p300 degradation Kuno A, Tanno M, Ishikawa S, Horio Y, Miura T.

Connexin-43 contributes to transmission of MitoKATP channel-derived redox signal to Akt-GSK-3" pathway in cardiomyocyte protection afforded by G protein-coupled receptors Ishikawa S, Kuno A, Miki T, Tanno T, Yano T, Kouzu H, Sato T, Sunaga D, Miura T.

Ventricular dysfunction and blunted response to adrenergic stimulation in obese type 2 diabetes predispose to fatal heart failure after infarction:Possible involvement of microRNA-1 down-regulation

Takada A, Miki T, Tanno M, Suzuki H, Yano T, Kuno A, Itoh T, Sato T, Miura T.

Increased ER stress is a fundamental mechanism for impairment of cardioprotective signaling in type 2

diabetes Kouzu H, Itoh T, Miki T, Tanno M, Yano Y, Sato T, Takada A, Sunaga D, Miura T.

43rd Annual Meeting and Scientific Exposition of American Society of Nephrology. Denver, USA, November 16-21, 2010

History of parathyroidectomy and survival among hemodialysis patients with secondary hyperparathyroidism: Results from a nationwide registry in Japan Komaba H, Taniguchi M, Wada A, Iseki K, Tsubakihara Y, Fukagawa M

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Regulation of mitochondrial GSK-3" for cell survival is impaired by multiple mechanisms in the diabetic myocardium Miura T, Miki T, Shimamoto K

Resveratrol induces repressive histone modifications through SIRT1 and suppresses cardiomyocyte hypertrophy Kuno A, Tanno M, Miura T, Horio Y, Shimamoto K

Loss of myocardial response to Jak2-mediated protective signaling in hypertensive hypertrophied hearts Yano T, Miura T, Miki T, Tanno M, Kuno A, Itoh T, Satoh T, Takada A, Ishikawa S, Shimamoto K

Down-regulation of microRNA199a affords protection against oxidant-induced cell death Ishikawa S, Miura T, Tanno M, Kuno A, Miki T, Itoh T, Satoh T, Shimamoto K

Mortality after myocardial infarction is increased by progressive heart failure in type 2 diabetic rats with high tissue calcineurin activity

Takada A, Miura T, Miki T, Tanno M, Kuno A, Yano T, Itoh T, Satoh T, Shimamoto K

Distinct roles of ER stress and calcineurin in impaired protective signaling in the diabetic myocardium

Itoh T, Miura T, Miki T, Yano T, Hotto H, Tanno M, Kuno A, Satoh T, Shimamoto K

Impaired cardioprotective signaling and alterations in microRNA expression in diabetic hearts

Miki T, Miura T, Suzuki H, Yano T, Takada A, Ishikawa S, Toyota M, Shimamoto K

Role of left atrial reservoir dysfunction in pathophysiology of diastolic heart failure

Kouzu H, Yuda S, Nishida J, Funayama N, Mochizuki A, Ichimura M, Doi T, Yamamoto H, Muranaka A,

Fujii N, Kokubu N, Shimoshige S, Hase M, Hashimoto A, Tsuchihashi K, Watanabe N, Shimamoto K.

Left atrial function following pulmonary vein isolation for patients with paroxysmal atrial fibrillation:a study of two-dimensional speckle tracking imaging' Yamamoto H, Yuda S, Nishida J, Funayama N, Mochizuki A, Ichimura M, Doi T, Kouzu H, Muranaka A,

Fujii N, Kokubu N, Shimoshige S, Hase M, Hashimoto A, Tsuchihashi K, Watanabe N, Shimamoto K.

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28

Quantitative measurement of circumferential carotid arterial strain by two-dimensional speckle tracking imaging in patients with coronary artery disease

Yuda S, Nishida J, Funayama N, Mochizuki A, Ichimura M, Doi T, Kouzu H, Yamamoto H, Muranaka A,

Fujii N, Kokubu N, Shimoshige S, Hase M, Hashimoto A, Tsuchihashi K, Watanabe N, Shimamoto K.

Prognostic value of cardiac sympathetic nerve activity in heart failure patients with preserved left ventricular ejection fraction. Doi T, Nakata T, Wakabayashi T, Kouzu H, Fujii N, Yuda S, Hase M, Hashimoto A, Tsuchihashi K,

Shimamoto K.

Consideration of the optimal right ventricular septal pacing site with electroanatomical

mapping.

Mochizuki A, Yamamoto H, Shimoshige S, Doi T, Kouzu H, Muranaka A, Kokubu N,

Fujii N, Yuda S, Hase M, Hashimoto A, Tsuchihashi K, Shimamoto K.

The impact of percutaneous cardiopulmonary assisted devices to treat patients under therapeutic

hypothermia in hemodynamic compromised State

Kokubu N, Yokoyama H, Otsuka Y, Yagi N, Yamanaka F, Yonemoto N, Nagao K, Nonogi H

'

Outcome after Aortic Valve Replacement with Aortic Stenosis : Effects of the Patient-Prosthesis

Mismatch on Left Ventricular Mass and Function

Muranaka A, Watanabe H, Mihara H, Aikawa M, Fukui T, Shimokawa T, Takanashi S, Umemura J,

Sumiyoshi S

Plasma B-type natriuretic peptide levels and the risk for cardiovascular events in rural communities in

Japan -The Tanno and Sobetsu Study Ohnishi H, Saitoh S, Akasaka H, Mitsumata K, Chiba M, Furugen M, Furukawa T, Mori M, Shimamoto K.

PERK haploinsufficiency leads to endoplsmic reticulum-related metabolic deterioration in diet-induced obesity Furuhashi M, Shimamoto K, Hotamisligil GS.

Angiotensin II stimulation in prepuberty induces sustained insulin resistance and hypertension via upregulated Rac-1, oxidative stress and inflammatory cytokines

Togashi N, Yamashita, Okazaki Y, Ohta H, Ishimura S, Yokoyama Y, Hyakukoku M, Furuhashi M, Yoshida H,

Shimamoto K.

± 83"#E5�Tgôg! ¬Ç 22ô 3­ 16-18#! 9´ Activation of SIRT1 modifies histone acetylation/methylation and attenuates cardiomyocyte hypertrophy

Kuno A, Tanno M, Horio Y

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29

± 107"#EõöTg³gUíOg! ¬Ç 22ô 4­ 9-11#! µ² ©��¶G�·vMi×P¸Ç�L¼ ! t¹xº¸J�¢M¢P¸Ç��·� ¡D»V:;×Pt ÛÜ! Ý, 2ò3~, ´Ù4Ú, OÒ�û , `à1[ , ßàá, �}��, °�:5, ]^_`, B®!

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Role of left atrial global and regional dysfunction in pathophysiology of diastolic heart failure

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Funayama N, Yuda S, Kaneko R, Muranaka A, Hashimoto A, Tsuchihashi K, Watanabe N, Shimamoto K.

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