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1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes in Crohn's disease. Gastroenterology. 1995 ;109(5):1462-7. 2. Nojima Y, Mimura T, Hamasaki K, Furuya H, Tanaka G, Nakajima A, Matsuhashi N, Yazaki Y. Chronic intestinal pseudoobstruction associated with autoantibodies against proliferating cell nuclear antigen. Arthritis Rheum. 1996 May;39(5):877-9. 3. Matsuhashi N, Nakajima A, Fukushima Y, Suzuki A, Yazaki Y, Konishi T, Hiraish M, Sato A, Tokunaga M. Three histologically different tiny gastric cancers developing adjacent to each other, resected endoscopically in a single mucosal piece. Am J Gastroenterol. 1996 Oct;91(10):2200-2. 4. Matsuhashi N, Nakajima A, Fukushima Y, Yazaki Y, Sato A, Hiraishi M, Konishi T. Sarcoid reactions in association with a leiomyosarcoma of the stomach. Am J Gastroenterol. 1996 Dec;91(12):2623-4. 5. Nakajima A, Kodama T, Yazaki Y, Takazoe M, Saito N, Suzuki R, Nishino H,Yamamoto K, Silver J, Matsuhashi N. Specific clonal T cell accumulation in intestinal lesions of Crohn's disease. J Immunol. 1996;157(12):5683-8. 6. Matsuhashi N, Nakajima A, Suzuki A, Akanuma M, Yazaki Y, Takazoe M. Nonsurgical strictureplasty for intestinal strictures in Crohn's disease:preliminary report of two cases. Gastrointest Endosc. 1997;45(2):176-8. 7. Matsuhashi N, Nakajima A, Fukushima Y, Yazaki Y, Oka T. Effects of sulindac on sporadic colorectal adenomatous polyps .Gut. 1997 ;40(3):344-9. 8. Nakajima N, Hanaki K, Shimizu YK, Ohnishi S, Gunji T, Nakajima A, Nozaki C, Mizuno K, Odawara T, Yoshikura H. Hybridization-AT-tailing (HybrAT) method for sensitive and strand-specific detection of DNA and RNA. Biochem Biophys Res Commun. 1998;248(3):613-20. 9. Matsuhashi N, Nakajima A, Shinohara K, Oka T, Yazaki Y. Rectal cancer after sulindac therapy for a sporadic adenomatous colonic polyp. Am J Gastroenterol. 1998 ;93(11):2261-6.

1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

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Page 1: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked

susceptibility and resistance genes in Crohn's disease. Gastroenterology. 1995 ;109(5):1462-7.

2. Nojima Y, Mimura T, Hamasaki K, Furuya H, Tanaka G, Nakajima A, Matsuhashi

N, Yazaki Y. Chronic intestinal pseudoobstruction associated with autoantibodies

against proliferating cell nuclear antigen. Arthritis Rheum. 1996 May;39(5):877-9.

3. Matsuhashi N, Nakajima A, Fukushima Y, Suzuki A, Yazaki Y, Konishi T, Hiraish

M, Sato A, Tokunaga M. Three histologically different tiny gastric cancers

developing adjacent to each other, resected endoscopically in a single mucosal piece.

Am J Gastroenterol. 1996 Oct;91(10):2200-2.

4. Matsuhashi N, Nakajima A, Fukushima Y, Yazaki Y, Sato A, Hiraishi M, Konishi T.

Sarcoid reactions in association with a leiomyosarcoma of the stomach. Am

J Gastroenterol. 1996 Dec;91(12):2623-4.

5. Nakajima A, Kodama T, Yazaki Y, Takazoe M, Saito N, Suzuki R, Nishino

H,Yamamoto K, Silver J, Matsuhashi N. Specific clonal T cell accumulation in

intestinal lesions of Crohn's disease. J Immunol. 1996;157(12):5683-8.

6. Matsuhashi N, Nakajima A, Suzuki A, Akanuma M, Yazaki Y, Takazoe M.

Nonsurgical strictureplasty for intestinal strictures in Crohn's disease:preliminary

report of two cases. Gastrointest Endosc. 1997;45(2):176-8.

7. Matsuhashi N, Nakajima A, Fukushima Y, Yazaki Y, Oka T. Effects of sulindac on

sporadic colorectal adenomatous polyps .Gut. 1997 ;40(3):344-9.

8. Nakajima N, Hanaki K, Shimizu YK, Ohnishi S, Gunji T, Nakajima A, Nozaki C,

Mizuno K, Odawara T, Yoshikura H. Hybridization-AT-tailing (HybrAT) method for

sensitive and strand-specific detection of DNA and RNA. Biochem

Biophys Res Commun. 1998;248(3):613-20.

9. Matsuhashi N, Nakajima A, Shinohara K, Oka T, Yazaki Y. Rectal cancer after

sulindac therapy for a sporadic adenomatous colonic polyp. Am J Gastroenterol.

1998 ;93(11):2261-6.

Page 2: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

10. Matsuhashi N, Nakajima A, Suzuki A, Yazaki Y, Takazoe M. Long-term outcome of

non-surgical strictureplasty using metallic stents for intestinal strictures in Crohn's

disease. Gastrointest Endosc. 2000;51(3):343-5.

11. Nakajima A, Yajima S, Shirakura T, Ito T, Kataoka Y, Ueda K, Nagoshi D,

Kanemoto H, Matsuhashi N. Rifampicin-associated pseudomembranous colitis. J

Gastroenterol. 2000;35(4):299-303.

12. Nakajima A, Matsuhashi N, Yazaki Y, Oka T, Sugano K. Details of hyperplastic

polyps of the stomach shrinking after anti-Helicobacter pylori therapy. J

Gastroenterol. 2000;35(5):372-5.

13. Nakajima A, Ohnishi S, Mimura T, Kubo K, Suzuki A, Yazaki Y, Matsuhashi N.

Protein-losing enteropathy associated with hypocomplementemia and anti-nuclear

antibodies. J Gastroenterol. 2000;35(8):627-30.

14. Matsuhashi N, Nakajima A, Watanabe K, Komeno Y, Suzuki A, Ohnishi S, Omata

M, Kondo K, Usui Y, Iwadare JI, Watanabe T, Nagawa H, Muto T. Tacrolimus in

corticosteroid-resistant ulcerative colitis. J Gastroenterol. 2000;35(8):635-40.

15. Nakajima A, Wada K, Miki H, Kubota N, Nakajima N, Terauchi Y, Ohnishi S,

Saubermann LJ, Kadowaki T, Blumberg RS, Nagai R, Matsuhashi N. Endogenous

PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion

injury. Gastroenterology. 2001;120(2):460-9.

16. Aoki K, Kikuchi T, Mukasa K, Ito S, Nakajima A, Satoh S, Okamura A, Sekihara H.

Dehydroepiandrosterone suppresses elevated hepatic glucose-6-phosphatase mRNA

level in C57BL/KsJ-db/db mice: comparison with troglitazone. Endocr J.

2000;47(6):799-804.

17.Wada K, Nakajima A, Blumberg RS. PPARgamma and inflammatory bowel disease:

a new therapeutic target for ulcerative colitis and Crohn's disease. Trends Mol Med.

2001;7(8):329-31.

18. Nakajima A, Iijima H, Neurath MF, Nagaishi T, Nieuwenhuis EE, Raychowdhury

R, Glickman J, Blau DM, Russell S, Holmes KV, Blumberg RS. Activation-induced

Page 3: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse

T lymphocyte function. J Immunol. 2002;168(3):1028-35.

19. Togawa J, Nagase H, Tanaka K, Inamori M, Umezawa T, Nakajima A, Naito M,

Sato S, Saito T, Sekihara H. Lactoferrin reduces colitis in rats via modulation of the

immune system and correction of cytokine imbalance. Am J

Physiol Gastrointest Liver Physiol. 2002;283(1):G187-95.

20. Shiojiri T, Wada K, Nakajima A, Katayama K, Shibuya A, Kudo C, Kadowaki T,

Mayumi T, Yura Y, Kamisaki Y. PPAR gamma ligands inhibit nitrotyrosine

formation and inflammatory mediator expressions in adjuvant-induced rheumatoid

arthritis mice. Eur J Pharmacol. 2002;448(2-3):231-8.

21.Zhu X, Peng J, Raychowdhury R, Nakajima A, Lencer WI, Blumberg RS. The heavy

chain of neonatal Fc receptor for IgG is sequestered in endoplasmic reticulum by

forming oligomers in the absence of beta2-microglobulin association. Biochem J.

2002;367(Pt 3):703-14.

22. Shibuya A, Wada K, Nakajima A, Saeki M, Katayama K, Mayumi T, Kadowaki T,

Niwa H, Kamisaki Y. Nitration of PPARgamma inhibits ligand-dependent

translocation into the nucleus in a macrophage-like cell line, RAW 264. FEBS Lett.

2002;525(1-3):43-7.

23.Osawa E, Nakajima A, Yoshida S, Omura M, Nagase H, Ueno N, Wada K,

Matsuhashi N, Ochiai M, Nakagama H, Sekihara H. Chemoprevention of precursors

to colon cancer by dehydroepiandrosterone (DHEA). Life Sci.

2002 ;70(22):2623-30.

24. Togawa J, Nagase H, Tanaka K, Inamori M, Nakajima A, Ueno N, Saito T,

Sekihara H. Oral administration of lactoferrin reduces colitis in rats via

modulation of the immune system and correction of cytokine imbalance. J

Gastroenterol Hepatol. 2002;17(12):1291-8.

25. Saubermann LJ, Nakajima A, Wada K, Zhao S, Terauchi Y, Kadowaki T, Aburatani

H, Matsuhashi N, Nagai R, Blumberg RS. Peroxisome proliferator-activated

Page 4: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent

acute colitis. Inflamm Bowel Dis. 2002;8(5):330-9.

26. Matsuhashi N, Akahane M, Nakajima A. Barium impaction therapy for refractory

colonic diverticular bleeding. AJR Am J Roentgenol. 2003;180(2):490-2. No abstract

available.

27. Inamori M, Togawa J, Nagase H, Abe Y, Umezawa T, Nakajima A, Saito T, Ueno N,

Tanaka K, Sekihara H, Kaifu H, Tsuboi H, Kayama H, Tominaga S, Nagura H.

Clinical characteristics of Japanese reflux esophagitis patients as determined by

Los Angeles classification. J Gastroenterol Hepatol. 2003;18(2):172-6.

28. Osawa E, Nakajima A, Wada K, Ishimine S, Fujisawa N, Kawamori T, Matsuhashi

N, Kadowaki T, Ochiai M, Sekihara H, Nakagama H. Peroxisome

proliferator-activated receptor gamma ligands suppress colon carcinogenesis

induced by azoxymethane in mice. Gastroenterology. 2003;124(2):361-7.

29. Nakajima A, Wada K, Katayama K, Saubermann L, Osawa E, Nagase H, Ueno N,

Matsuhashi N, Aburatani H. Gene expression profile after peroxisome proliferator

activator receptor-gamma ligand administration in dextran sodium sulfate mice.

J Gastroenterol. 2002;37 Suppl 14:62-6.

30. Nagase H, Nakajima A, Sekihara H, York DA, Bray GA. Regulation of feeding

behavior, gastric emptying, and sympathetic nerve activity to interscapular brown

adipose tissue by galanin and enterostatin: the involvement of vagal-central

nervous system interactions. J Gastroenterol. 2002 ;37 Suppl 14:118-27.

31. Katayama K, Wada K, Nakajima A, Mizuguchi H, Hayakawa T, Nakagawa S,

Kadowaki T, Nagai R, Kamisaki Y, Blumberg RS, Mayumi T. A novel PPAR gamma

gene therapy to control inflammation associated with inflammatory bowel disease in

a murine model. Gastroenterology. 2003;124(5):1315-24.

32. Kudo C, Kori M, Matsuzaki K, Yamai K, Nakajima A, Shibuya A, Niwa H,

Kamisaki Y, Wada K. Diclofenac inhibits proliferation and differentiation of

neural stem cells. Biochem Pharmacol. 2003 ;66(2):289-95.

Page 5: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

33. Inamori M, Togawa J, Takahashi K, Yoneda M, Fujisawa N, Iwasaki T, Ozawa Y,

Kikuchi T, Muramatsu K, Chiguchi G, Matsumoto S, Kawamura H, Abe Y,

Kirikoshi H, Kobayashi N, Sakaguchi T, Takamura T, Nakajima A, Ueno N,

Sekihara H. Comparison of the effect on intragastric pH of a single dose of

omeprazole or rabeprazole: which is suitable for on-demand therapy? J

Gastroenterol Hepatol. 2003;18(9):1034-8.

34.Nakajima A. Matsuhashi N, Nishi Y, Nagoshi D, Kanemoto H, Epidemic

enterocolitis possibly as a result of Norwalk virus infection presenting as ischemic

colitis Digestive Endoscopy.2003:15:138-141.

35. Aoki K, Nakajima A, Mukasa K, Osawa E, Mori Y, Sekihara H. Prevention of

diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone. J

Steroid Biochem Mol Biol. 2003 ;85(2-5):469-72. Review.

36. Inamori M, Togawa J, Kawamura H, Abe Y, Naitoh H, Nagase H, Nakajima A,

Saito T, Tominaga S, Ueno N, Tanaka K, Sekihara H. Severe ulceration of the

stomach after endoscopic injection sclerotherapy. Endoscopy.

2003;35(12):1082.

37. Matsuhashi N, Nakajima A, Nomura S, Kaminishi M. Inflammatory fibroid

polyps of the stomach and Helicobacter pylori. J Gastroenterol Hepatol.

2004;19(3):346-7.

38. Abe Y, Inamori M, Togawa J, Kikuchi T, Muramatsu K, Chiguchi G, Kawamura H,

Kobayashi N, Kirikoshi H, Sakaguchi T, Takamura T, Nakajima A, Ueno N,

Sekihara H. The comparative effects of single intravenous doses of omeprazole and

famotidine on intragastric pH. J Gastroenterol. 2004;39(1):21-5.

39. Iijima H, Neurath MF, Nagaishi T, Glickman JN, Nieuwenhuis EE, Nakajima A,

Chen D, Fuss IJ, Utku N, Lewicki DN, Becker C, Gallagher TM, Holmes KV,

Blumberg RS. Specific regulation of T helper cell 1-mediated murine colitis by

CEACAM1. J Exp Med. 2004;199(4):471-82.

40. Katayama K, Wada K, Miyoshi H, Ohashi K, Tachibana M, Furuki R, Mizuguchi H,

Hayakawa T, Nakajima A, Kadowaki T, Tsutsumi Y, Nakagawa S, Kamisaki Y,

Page 6: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

Mayumi T. RNA interfering approach for clarifying the PPARgamma pathway using

lentiviral vector expressing short hairpin RNA. FEBS Lett.

2004;560(1-3):178-82.

41. Chen D, Iijima H, Nagaishi T, Nakajima A, Russell S, Raychowdhury R, Morales V,

Rudd CE, Utku N, Blumberg RS. Carcinoembryonic antigen-related cellular

adhesion molecule 1 isoforms alternatively inhibit and costimulate human T cell

function. J Immunol. 2004;172(6):3535-43.

42. Yamada Y, Nakajima A, Sekihara H. Supplement. Anti-apoptotic effect of

dehydroepiandrosterone and its role in an aging society. Intern Med.

2004 ;43(2):158-60.

43. Kudo C, Wada K, Masuda T, Yonemura T, Shibuya A, Fujimoto Y, Nakajima A,

Niwa H, Kamisaki Y. Nonylphenol induces the death of neural stem cells due to

activation of the caspase cascade and regulation of the cell cycle. J Neurochem.

2004;88(6):1416-23.

44.Takahashi H, Nakajima A, Sekihara H. Dehydroepiandrosterone (DHEA) and its

sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes.

J Steroid Biochem Mol Biol. 2004;88(3):261-4.

45. Wada K, Nakajima A, Takahashi H, Yoneda M, Fujisawa N, Ohsawa E, Kadowaki

T, Kubota N, Terauchi Y, Matsuhashi N, Saubermann LJ, Nakajima N, Blumberg

RS. Protective effect of endogenous PPARgamma against acute gastric mucosal

lesions associated with ischemia-reperfusion. Am J

Physiol Gastrointest Liver Physiol. 2004;287(2):G452-8.

46. Yoshii T, Mizuno K, Hirose T, Nakajima A, Sekihara H, Ohno S. sPAR-3, a

splicing variant of PAR-3, shows cellular localization and an expression pattern

different from that of PAR-3 during enterocyte polarization. Am J

Physiol Gastrointest Liver Physiol. 2005;288(3):G564-70.

47. Shimamura T, Yasuda J, Ino Y, Gotoh M, Tsuchiya A, Nakajima A, Sakamoto M,

Kanai Y, Hirohashi S. Dysadherin expression facilitates cell motility and

Page 7: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

metastatic potential of human pancreatic cancer cells. Cancer Res.

2004 ;64(19):6989-95.

48. Yoneda M, Wada K, Katayama K, Nakajima N, Iwasaki T, Osawa E, Mukasa

K,Yamada Y, Blumberg RS, Sekihara H, Nakajima A. A novel therapy for acute

hepatitis utilizing dehydroepiandrosterone in the murine model of hepatitis.

Biochem Pharmacol. 2004 ;68(11):2283-9.

49. Iwasaki T, Mukasa K, Yoneda M, Ito S, Yamada Y, Mori Y, Fujisawa N, Fujisawa T,

Wada K, Sekihara H, Nakajima A. Marked attenuation of production of collagen

type I from cardiac fibroblasts by dehydroepiandrosterone. Am J

Physiol Endocrinol Metab. 2005;288(6):E1222-8.

50.Katayama K, Wada K, Nakajima A, Kamisaki Y, Mayumi T. Nuclear receptors as

targets for drug development: the role of nuclear receptors during neural stem cell

proliferation and differentiation. J Pharmacol Sci. 2005;97(2):171-6. Review.

51. Schaefer KL, Denevich S, Ma C, Cooley SR, Nakajima A, Wada K, Schlezinger J,

Sherr D, Saubermann LJ. Intestinal antiinflammatory effects of thiazolidenedione

peroxisome proliferator-activated receptor-gamma ligands on T helper type 1

chemokine regulation include nontranscriptional control mechanisms.

Inflamm Bowel Dis. 2005;11(3):244-52.

52.Inamori M, Togawa J, Chiguchi G, Abe Y, Kikuchi T, Muramatsu K, Kawamura H,

Kobayashi N, Kirikoshi H, Shimamura T, Sakaguchi T, Takamura T, Ueno N,

Nakajima A. Evaluation of the effects of anti-secretory drugs on intragastric acidity:

is combined therapy with a proton pump inhibitor and an H2 receptor antagonist

effective as initial treatment? J Gastroenterol. 2005;40(2):213-4.

53.Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, Turner

JR, Nakajima A, Borkan SC, Saubermann LJ. Peroxisome proliferator-activated

receptor gamma inhibition prevents adhesion to the extracellular matrix and

induces anoikis in hepatocellular carcinoma cells. Cancer Res. 2005;65(6):2251-9.

54. Togawa J, Inamori M, Fujisawa N, Takahashi H, Yoneda M, Kawamura H, Abe

Y,Kirikoshi H, Kobayashi N, Sakaguchi T, Takamura T, Nakajima A, Ueno N,

Page 8: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

Sekihara H. Efficacy of a triple therapy with rabeprazole, amoxicillin, and

faropenem as second-line treatment after failure of initial Helicobacter pylori

eradication therapy. Hepatogastroenterology. 2005;52(62):645-8.

55. Lu J, Imamura K, Nomura S, Mafune K, Nakajima A, Kadowaki T, Kubota N,

Terauchi Y, Ishii G, Ochiai A, Esumi H, Kaminishi M. Chemopreventive effect of

peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice.

Cancer Res. 2005;65(11):4769-74.

56.Masuda T, Wada K, Nakajima A, Okura M, Kudo C, Kadowaki T, Kogo M, Kamisaki

Y. Critical role of peroxisome proliferator-activated receptor gamma on anoikis and

invasion of squamous cell carcinoma. Clin Cancer Res. 2005;11(11):4012-21.

57. Inamori M, Togawa J, Iwasaki T, Ozawa Y, Kikuchi T, Muramatsu K, Chiguchi G,

Matsumoto S, Kawamura H, Abe Y, Kirikoshi H, Kobayashi N, Shimamura T,

Kubota K, Sakaguchi T, Saito S, Ueno N, Nakajima A. Early effects of lafutidine

or rabeprazole on intragastric acidity: which drug is more suitable for on-demand

use? J Gastroenterol. 2005;40(5):453-8.

58. Kubota K, Abe Y, Inamori M, Kawamura H, Kirikoshi H, Kobayashi N, Saito S,

Ueno N, Nakajima A. Percutaneous transhepatic gallbladder stenting for

recurrent acute acalculous cholecystitis after failed endoscopic attempt.

J Hepatobiliary Pancreat Surg. 2005;12(4):286-9.

59. Iwasaki T, Nakajima A, Yoneda M, Yamada Y, Mukasa K, Fujita K, Fujisawa N,

Wada K, Terauchi Y. Serum ferritin is associated with visceral fat area and

subcutaneous fat area. Diabetes Care. 2005;28(10):2486-91.

60.Katayama K, Wada K, Nakajima A, Kamisaki Y, Mayumi T. Nuclear receptors as

targets for drug development: the role of nuclear receptors during neural stem cell

proliferation and differentiation. J Pharmacol Sci. 2005 Feb;97(2):171-6. Epub 2005

Feb 11

61. Osawa E, Nakajima A, Fujisawa T, Kawamura YI, Toyama-Sorimachi N,

Nakagama H, Dohi T. Predominant T helper type 2-inflammatory responses

promote murine colon cancers. Int J Cancer. 2006;118(9):2232-6.

Page 9: 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M ... · 1. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. HLA-linked susceptibility and resistance genes

62. Inamori M, Ueno N, Fujita K, Fujisawa T, Fujisawa N, Yoneda M, Takahashi H,

Ikeda T, Kawamura H, Abe Y, Kato A, Kirikoshi H, Kobayashi N, Shimamura T,

Kubota K, Saito S, Sakaguchi T, Yamanaka S, Inayama Y, Nakajima A. Education

and imaging. Gastrointestinal: Gastrointestinal metastases from malignant

melanoma. J Gastroenterol Hepatol. 2006;21(1 Pt 2):327.

63. Wada K, Nakajima A, Katayama K, Kudo C, Shibuya A, Kubota N, Terauchi Y,

Tachibana M, Miyoshi H, Kamisaki Y, Mayumi T, Kadowaki T, Blumberg RS.

Peroxisome proliferator-activated receptor gamma-mediated regulation of neural

stem cell proliferation and differentiation. J Biol Chem. 2006;281(18):12673-81.

64. Iwasaki T, Nakajima A, Yoneda M, Terauchi Y. Relationship between the serum

concentrations of C-reactive protein and parameters of adiposity and insulin

resistance in patients with type 2 diabetes mellitus. Endocr J. 2006;53(3):345-56.

65. Ito H, Funahashi S, Yamauchi N, Shibahara J, Midorikawa Y, Kawai S, Kinoshita

Y, Watanabe A, Hippo Y, Ohtomo T, Iwanari H, Nakajima A, Makuuchi M,

Fukayama M, Hirata Y, Hamakubo T, Kodama T, Tsuchiya M, Aburatani H.

Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a

potential therapeutic and diagnostic target. Clin Cancer Res. 2006;12(11 Pt

1):3257-64.

66. Inamori M, Shimamura T, Nagase H, Abe Y, Umezawa T, Nakajima A, Saito T,

Ueno N, Tanaka K, Sekihara H, Togawa J, Kaifu H, Tsuboi H, Kayama H,

Tominaga S. mRNA expression of inducible nitric oxide synthase, endothelial

nitric oxide synthase and vascular endothelial growth factor in esophageal mucosa

biopsy specimens from patients with reflux esophagitis. Hepatogastroenterology.

2006;53(69):361-5.

67. Kayama H, Inamori M, Togawa J, Shimamura T, Tokita Y, Umezawa T, Sakaguchi

T, Naitoh M, Nagase H, Nakajima A, Saito T, Tominaga S, Ueno N, Tanaka K,

Sekihara H. Pleural effusions following endoscopic injection sclerotherapy for

cirrhotic patients with esophageal varices. Hepatogastroenterology.

2006;53(69):376-80.

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68. Takahashi H, Fujita K, Fujisawa T, Yonemitsu K, Tomimoto A, Ikeda I, Yoneda M,

Masuda T, Schaefer K, Saubermann LJ, Shimamura T, Saitoh S, Tachibana M,

Wada K, Nakagama H, Nakajima A. Inhibition of peroxisome

proliferator-activated receptor gamma activity in esophageal carcinoma cells results

in a drastic decrease of invasive properties. Cancer Sci. 2006 Sep;97(9):854-60.

69. Abe Y, Inamori M, Fujita K, Fujisawa T, Fujisawa N, Yoneda M, Takahashi H,

Ikeda T, Hara K, Akiyama T, Kawamura H, Kato A, Kirikoshi H, Kobayashi N,

Kubota K, Saito S, Sasaki T, Inayama Y, Ueno N, Nakajima A. Gastrointestinal:

rectal polyp associated with schistosomiasis. J Gastroenterol Hepatol.

2006;21(7):1216.

70. Hayashi M, Inamori M, Goto K, Akiyama T, Fujita K, Ikeda I, Fujisawa T,

Takahashi H, Yoneda M, Hara K, Abe Y, Kirikoshi H, Kubota K, Saito S, Ueno N,

Nakajima A, Hamada Y, Fukutomi H, Satsuta H. Blastocystis hominis infection in

patient with regular dialysis. J Gastroenterol. 2006;41(6):605-6.

71. Wada K, Arita M, Nakajima A, Katayama K, Kudo C, Kamisaki Y, Serhan CN.

Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell

proliferation and differentiation. FASEB J. 2006;20(11):1785-92.

72. Inamori M, Akiyama T, Akimoto K, Takahashi H, Abe Y, Nakajima A. Evaluation

of postprandial 3 h pH monitoring for gastroesophageal reflux disease: is there a

possibility of streamlining the 24 h test? J Gastroenterol Hepatol.

2006;21(11):1761-2.

73. Kubota K, Kakuta Y, Kawamura S, Abe Y, Inamori M, Kawamura H, Kirikoshi H,

Kobayashi N, Saito S, Nakajima A. Undifferentiated spindle-cell carcinoma of the

gallbladder: an immunohistochemical study. J Hepatobiliary Pancreat Surg.

2006;13(5):468-71.

74. Nagaishi T, Iijima H, Nakajima A, Chen D, Blumberg RS. Role of CEACAM1 as a

regulator of T cells. Ann N Y Acad Sci. 2006;1072:155-75. Review.

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75. Nagaishi T, Pao L, Lin SH, Iijima H, Kaser A, Qiao SW, Chen Z, Glickman J, Najjar

SM, Nakajima A, Neel BG, Blumberg RS. SHP1 phosphatase-dependent T cell

inhibition by CEACAM1 adhesion molecule isoforms. Immunity. 2006; (5):769-81.

76. Schaefer KL, Takahashi H, Morales VM, Harris G, Barton S, Osawa E, Nakajima A,

Saubermann LJ. PPARgamma inhibitors reduce tubulin protein levels by a

PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell

cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells. Int

J Cancer. 2007;120(3):702-13.

77. Nomura S, Nakajima A, Ishimine S, Matsuhashi N, Kadowaki T, Kaminishi M.

Differential expression of peroxisome proliferator-activated receptor in

histologically different human gastric cancer tissues. J Exp Clin Cancer Res.

2006 ;25(3):443-8.

78. Yamada Y, Sekihara H, Omura M, Yanase T, Takayanagi R, Mune T, Yasuda K,

Ishizuka T, Ueshiba H, Miyachi Y, Iwasaki T, Nakajima A, Nawata H. Changes in

serum sex hormone profiles after short-term low-dose administration of

dehydroepiandrosterone (DHEA) to young and elderly persons. Endocr J.

2007;54(1):153-62.

79. Ihara A, Wada K, Yoneda M, Fujisawa N, Takahashi H, Nakajima A. Blockade of

leukotriene B4 signaling pathway induces apoptosis and suppresses cell

proliferation in colon cancer. J Pharmacol Sci. 2007;103(1):24-32.

80. Kobayashi N, Hiraoka N, Yamagami W, Ojima H, Kanai Y, Kosuge T, Nakajima A,

Hirohashi S. FOXP3+ regulatory T cells affect the development and progression of

hepatocarcinogenesis. Clin Cancer Res. 2007;13(3):902-11.

81. Goto K, Hayashi M, Inamori M, Akiyama T, Ikeda T, Fujita K, Ikeda I, Fujisawa T,

Takahashi H, Yoneda M, Hara K, Yasuzaki H, Abe Y, Kirikoshi H, Kubota K, Saito

S, Kawana I, Ueno N, Sakashita T, Nakajima A. Education and imaging.

Gastrointestinal: diphyllobothriasis. J Gastroenterol Hepatol. 2007;22(3):445.

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82. Kubota K, Fujisawa T, Abe Y, Inamori M, Kirikoshi H, Saito S, Nakajima A.

Clinical significance of the duodenal papilla in patients with separate orifices for the

bile and pancreatic ducts. J Gastroenterol. 2007;42(1):70-8.

83. Yoneda M, Iwasaki T, Fujita K, Kirikoshi H, Inamori M, Nozaki Y, Maeyama S,

Wada K, Saito S, Terauchi Y, Nakajima A. Hypoadiponectinemia plays a crucial

role in the development of nonalcoholic Fatty liver disease in patients with type 2

diabetes mellitus independent of visceral adipose tissue. Alcohol Clin Exp Res.

2007;31(1 Suppl):S15-21.

84.Ishida H, Wada K, Masuda T, Okura M, Kohama K, Sano Y, Nakajima A, Kogo M,

Kamisaki Y. Critical role of estrogen receptor on anoikis and invasion of squamous

cell carcinoma. Cancer Sci. 2007;98(5):636-43.

85.Yamanaka H, Inamori M, Fujisawa N, Akimoto K, Akiyama T, Fujita K, Takahashi

H, Yoneda M, Abe Y, Kirikoshi H, Kubota K, Saito S, Ueno N, Nakajima A. Two

cases of pyloduodenal stenosis: the efficiency of gastric emptying evaluation using

13C continuous breath test (BreathID System). Digestion. 2006;74(3-4):238.

86. Fujita K, Yoneda M, Wada K, Mawatari H, Takahashi H, Kirikoshi H, Inamori M,

Nozaki Y, Maeyama S, Saito S, Iwasaki T, Terauchi Y, Nakajima A. Telmisartan,

An Angiotensin II Type 1 Receptor Blocker, Controls Progress of Nonalcoholic

Steatohepatitis in Rats. Dig Dis Sci. 2007;52(12):3455-64.

87. Yoneda M, Fujita K, Inamori M, Tamano M, Hiraishi H, Nakajima A Transient

elastography in patients with non-alcoholic fatty liver disease (NAFLD). Gut.

2007;56(9):1330-1.

88. Sato T, Chiguchi G, Inamori M, Sakai H, Fujisawa N, Akiyama T, Akimoto K,

Fujita K, Takahashi H, Yoneda M, Abe Y, Kubota K, Ueno N, Nakajima A.

Protein-losing gastroenteropathy and gastric polyps: successful treatment by

Helicobacter pylori eradication. Digestion. 2007;75(2-3):99.

89. Yoneda M, Inamori M, Iwasaki T, Akiyama T, Fujita K, Takahashi H, Abe Y,

Kubota K, Ueno N, Shiiba M, Abe A, Nagashima T, Inoue T, Nakajima A.

Balloon-occluded retrograde transvenous obliteration for gastric varices with plural

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draining veins: effectiveness of coil embolization for collaterals. Digestion.

2007;75(2-3):100.

90. Sato T, Sakai H, Iida H, Inamori M, Akiyama T, Akimoto K, Fujita K, Takahashi H,

Yoneda M, Abe Y, Kubota K, Saito S, Ueno N, Takeshita Y, Nakajima A.

Protein-losing gastroenteropathy in a patient with pityriasis rubra pilaris.

Digestion. 2007;75(2-3):98.

91. Yoneda M, Mawatari H, Fujita K, Yonemitsu K, Kato S, Takahashi H, Kirikoshi H,

Inamori M, Nozaki Y, Abe Y, Kubota K, Saito S, Iwasaki T, Terauchi Y, Togo S,

Maeyama S, Nakajima A. Type IV collagen 7s domain is an independent clinical

marker of the severity of fibrosis in patients with nonalcoholic steatohepatitis before

the cirrhotic stage. J Gastroenterol. 2007;42(5):375-81.

92. Sakai H, Inamori M, Sato T, Tomimoto A, Akiyama T, Akimoto K, Endo H, Fujita K,

Takahashi H, Yoneda M, Abe Y, Kirikoshi H, Kubota K, Saito S, Ueno N, Nakajima

A. Colocutaneous fistula after percutaneous endoscopic gastrostomy. Digestion.

2007;75(2-3):103.

93. Inamori M, Akiyama T, Akimoto K, Fujita K, Takahashi H, Yoneda M, Abe Y,

Kubota K, Saito S, Ueno N, Nakajima A. Early effects of peppermint oil on gastric

emptying: a crossover study using a continuous real-time 13C breath test (BreathID

system). J Gastroenterol. 2007;42(7):539-42.

94. Inamori M, Akimoto K, Akiyama T, Fujita K, Takahashi H, Yoneda M, Abe Y,

Kirikoshi H, Kubota K, Saito S, Ueno N, Nakajima A. Is oral combination therapy

with a proton-pump inhibitor and H2 receptor antagonist effective as initial

treatment? J Gastroenterol. 2007;42(6):510-1.

95. Yoneda M, Mawatari H, Fujita K, Iida H, Yonemitsu K, Kato S, Takahashi H,

Kirikoshi H, Inamori M, Nozaki Y, Abe Y, Kubota K, Saito S, Iwasaki T, Terauchi Y,

Togo S, Maeyama S, Nakajima A. High-sensitivity C-reactive protein is an

independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the

severity of fibrosis in NASH. J Gastroenterol. 2007;42(7):573-82.

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96. Yanagisawa S, Inamori M, Endo H, Iida H, Akimoto K, Sakamoto Y, Akiyama T,

Fujita K, Yoneda M, Takahashi H, Abe Y, Kobayashi N, Kirikoshi H, Kubota K,

Ueno N, Nakajima A. Knee pain and swelling secondary to ulcerative colitis.

Digestion. 2007;75(2-3):144.

97. Abe Y, Inamori M, Akimoto K, Endo H, Iida H, Mawatari H, Nozaki Y, Akiyama

T,Sakamoto Y, Fujita K, Takahashi H, Yoneda M, Kobayashi N, Kubota K, Ueno N,

Nakajima A. Gastric bleeding after endoscopic injection sclerotherapy for

esophageal varices. Digestion. 2007;75(2-3):145.

98. Kawamura H, Inamori M, Akiyama T, Akimoto K, Fujita K, Takahashi H, Yoneda

M, Abe Y, Kubota K, Ueno N, Inayama Y, Harada H, Rino Y, Nakajima A. Argon

plasma coagulation for a bleeding gastrointestinal stromal tumor. Digestion.

2007;75(2-3):164.

99. Sakai H, Inamori M, Iida H, Akimoto K, Endo H, Nozaki Y, Akiyama T, Sakamoto Y,

Fujita K, Takahashi H, Yoneda M, Abe Y, Kubota K, Ueno N, Kusakabe A,

Nakajima A. Recovery of a Misinserted Gastrostomy Tube during Replacement:

Effectiveness of Gastropexy Using a 'Funada Style' Kit. Digestion. 2007;75(4):179.

100. Sakai E, Takahashi H, Inamori M, Endo H, Akiyama T, Akimoto K, Mawatari H,

Nozaki Y, Fujita K, Yoneda M, Goto A, Abe Y, Kobayashi N, Kubota K, Ueno N,

Nakajima A. Utility of Endoscopic Argon Plasma Coagulation in the Treatment of

Radiation Proctitis. Digestion. 2007;75(4):180.

101. Yoneda M, Saito S, Ikeda T, Fujita K, Mawatari H, Kirikoshi H, Inamori M,

Nozaki Y, Akiyama T, Takahashi H, Abe Y, Kubota K, Iwasaki T, Terauchi Y, Togo

S, Nakajima A. Hepatitis C virus directly associates with insulin resistance

independent of the visceral fat area in nonobese and nondiabetic patients.

J Viral Hepat. 2007;14(9):600-7.

102. Iwasaki T, Yoneda M, Kawasaki S, Fujita K, Nakajima A, Terauchi Y. Hepatic

fat content-independent association of the serum level of

gamma-glutamyltransferase with visceral adiposity, but not subcutaneous adiposity.

Diabetes Res Clin Pract. 2008 Jan;79(1):e13-4. Epub 2007 Aug 14.

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103. Endo H, Inamori M, Murakami T, Yoshida K, Higurashi T, Iida H, Takahashi H,

Akiyama T, Akimoto K, Sakamoto Y, Fujita K, Yoneda M, Abe Y, Kobayashi N,

Kubota K, Nakajima A. Usefulness of Transnasal Ultrathin Endoscopy for the

Placement of a Postpyloric Decompression Tube. Digestion. 2007 ;75(4):181 [Epub

ahead of print]

104. Yanagiya T, Tanabe A, Iida A, Saito S, Sekine A, Takahashi A, Tsunoda

T,Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki

H,Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T,

Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H,

Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K.

Association of single-nucleotide polymorphisms in MTMR9 gene with obesity. Hum

Mol Genet. 2007;16(24):3017-26.

105. Endo H, Kondo Y, Kawagoe K, Ohya TR, Yanagawa T, Asayama M, Hisatomi K,

Teratani T, Yoneda M, Inamori M, Nakajima A, Matsuhashi N. Lupus enteritis

detected by capsule endoscopy. Intern Med. 2007;46(18):1621-2.

106. Sakai E, Inokuchi Y, Inamori M, Uchiyama T, Iida H, Takahashi H, Akiyama T,

Akimoto K, Sakamoto Y, Fujita K, Yoneda M, Abe Y, Kobayashi N, Kubota K, Saito

S, Nakajima A. Rectal Fecaloma: Successful Treatment Using Endoscopic Removal.

Digestion. 2007;75(4):198.

107. Iwasaki T, Yoneda M, Nakajima A, Terauchi Y. Serum butyrylcholinesterase is

strongly associated with adiposity, the serum lipid profile and insulin resistance.

Intern Med. 2007;46(19):1633-9. Epub 2007 Oct 1.

108. Yoneda M, Endo H, Nozaki Y, Tomimoto A, Fujisawa T, Fujita K, Yoneda K,

Takahashi H, Saito S, Iwasaki T, Yamamoto S, Tsutsumi S, Aburatani H, Wada K,

Hotta K, Nakajima A. Life style-related diseases of the digestive system: gene

expression in nonalcoholic steatohepatitis patients and treatment strategies.

J Pharmacol Sci. 2007;105(2):151-6. .

109. Saito S, Heller T, Yoneda M, Takahashi H, Nakajima A, Liang JT.

Lifestyle-related diseases of the digestive system: a new in vitro model of hepatitis C

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virion production: application of basic research on hepatitis C virus to clinical

medicine. J Pharmacol Sci. 2007;105(2):138-44.

110.Wada K, Sakamoto H, Nishikawa K, Sakuma S, Nakajima A, Fujimoto Y, Kamisaki

Y. Life style-related diseases of the digestive system: endocrine disruptors stimulate

lipid accumulation in target cells related to metabolic syndrome. J

Pharmacol Sci. 2007;105(2):133-7.

111. Takahashi H, Yoneda K, Tomimoto A, Endo H, Fujisawa T, Iida H, Mawatari

H,Nozaki Y, Ikeda T, Akiyama T, Yoneda M, Inamori M, Abe Y, Saito S, Nakajima A,

Nakagama H. Life style-related diseases of the digestive system: colorectal cancer

as a life style-related disease: from carcinogenesis to medical treatment. J

Pharmacol Sci. 2007;105(2):129-32.

112.Nakajima A, Wada K. Life style-related diseases of the digestive system: from

molecular mechanisms to therapeutic strategies: preface. J

Pharmacol Sci. 2007;105(2):127-8.

113. Shimamura T, Royal RE, Kioi M, Nakajima A, Husain SR, Puri RK.

Interleukin-4 cytotoxin therapy synergizes with gemcitabine in a mouse model of

pancreatic ductal adenocarcinoma. Cancer Res. 2007;67(20):9903-12.

114. Sakai H, Inamori M, Sato T, Akimoto K, Akiyama T, Fujita K, Yoneda M,

Takahashi H, Goto A, Kusakabe A, Abe Y, Kirikoshi H, Kubota K, Ueno N, Rino Y,

Nakajima A. Giant subcutaneous abscess after percutaneous endoscopic

gastrostomy. Endoscopy. 2007 Feb;39 Suppl 1:E264.

115. Akimoto K, Inamori M, Akiyama T, Endo H, Fujita K, Yoneda M, Takahashi H,

Goto A, Abe Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Ueno N, Nakajima A.

Sclerosant extravasation following endoscopic injection sclerotherapy for bleeding

gastric varices. Endoscopy. 2007 39 Suppl 1:E242

116. Ikeda I, Tomimoto A, Wada K, Fujisawa T, Fujita K, Yonemitsu K, Nozaki Y, Endo

H, Takahashi H, Yoneda M, Inamori M, Kubota K, Saito S, Nagashima Y, Nakagama

H, Nakajima A. 5-Aminosalicylic Acid Given in the Remission Stage of Colitis

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Suppresses Colitis-Associated Cancer in a Mouse Colitis Model. Clin Cancer Res.

2007;13(21):6527-6531.

117. Kubota K, Iida H, Fujisawa T, Yoneda M, Inamori M, Abe Y, Kirikoshi H, Saito S,

Ohshiro H, Kakuta Y, Nakajima A Clinical factors predictive of spontaneous

remission or relapse in cases of autoimmune pancreatitis. Gastrointest Endosc.

2007;66(6):1142-1151.

118. Kubota K, Iida H, Fujisawa T, Ogawa M, Inamori M, Saito S, Kakuta Y, Oshiro

H,Nakajima A. Clinical significance of swollen duodenal papilla in autoimmune

pancreatitis.Pancreas. 2007;35(4):e51-60.

119. Yoneda M, Yoneda M, Mawatari H, Fujita K, Endo H, Iida H, Nozaki Y,

Yonemitsu K, Higurashi T, Takahashi H, Kobayashi N, Kirikoshi H, Abe Y, Inamori

M, KubotaK, Saito S, Tamano M, Hiraishi H, Maeyama S, Yamaguchi N, Togo S,

Nakajima A. Noninvasive assessment of liver fibrosis by measurement of stiffness in

patients with nonalcoholic fatty liver disease (NAFLD). Dig Liver Dis. 2008

May;40(5):371-8. Epub 2007 Dec 20.

120. Iwasaki T, Togashi Y, Ohshige K, Yoneda M, Fujita K, Nakajima A, Terauchi Y.

Neither the presence of metabolic syndrome as defined by the IDF guideline nor an

increased waist circumference increased the risk of microvascular or macrovascular

complications in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract.

2008 Mar;79(3):427-32.

121. Akiyama T, Inamori M, Saito S, Takahashi H, Yoneda M, Fujita K, Fujisawa

T,Abe Y, Kirikoshi H, Kubota K, Ueda M, Tanaka K, Togo S, Ueno N, Shimada

H,Nakajima A. Levovist ultrasonography imaging in intracystic hemorrhage of

simple liver cyst. World J Gastroenterol. 2008;14(5):805-7.

122.Iida H, Inamori M, Sekino Y, Endo H, Akiyama T, Fujita K, Takahashi H, Yoneda

M, Kobayashi N, Abe Y, Kirikoshi H, Kubota K, Saito S, Oshiro H, Rino Y, Nakajma

A. Acute appendicitis associated with Peutz-Jeghers-type hamartoma of the

appendix. Dig Dis Sci. 2008; 53 (10): 2832-2833.

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123.Kobayashi N, Inamori M, Fujita K, Fujisawa T, Fujisawa N, Takahashi H, Yoneda

M, Abe Y, Kawamura H, Shimamura T, Kirikoshi H, Kubota K, Sakaguchi T, Saito

S, Saubermann LJ, Nakajima A. Characterization of K-ras Gene Mutations in

Association with Mucinous Hypersecretion in Intraductal Papillary-Mucinous

Neoplasms. J Hepatobiliary Pancreat Surg. 2008;15(2):169-77.

124.Sakai E, Takahashi H, Inamori M, Endo H, Akiyama T, Akimoto K, Mawatari H,

Nozaki Y, Fujita K, Yoneda M, Goto A, Abe Y, Kobayashi N, Kubota K, Saito S,

Nakajima A. Usefulness of multidetector computed tomography for detection of the

obstructive point in a patient with ileus. Dig Dis Sci. 2008 Dec;53(12):3264.

125.Nozaki Y, Kobayashi N, Shimamura T, Akiyama T, Inamori M, Iida H, Endo H,

Fujita K, Yoneda M, Takahashi H, Abe Y, Kirikoshi H, Kubota K, Saito S, Nakajima

A. Colonic metastasis from hepatocellular carcinoma: manifested by

gastrointestinal bleeding. Dig Dis Sci. 2008 Dec;53(12):3265-6.

126.Nakao S, Akimoto K, Inamori M, Suzuki A, Suzuki K, Iida H, Endo H, Akiyama T,

Fujita K, Yoneda M, Takahashi H, Abe Y, Kobayashi N, Kubota K, Yamanaka S,

Nakajima A. Antiphospholipid syndrome manifested by gastrointesitinal bleeding:

Can we overlook endoscopically-revealed small lesions? Digestion. 2008 Apr

22;77(3-4):139-140 [Epub ahead of print]

127.Endo H, Matsuhashi N, Inamori M, Akimoto K, Ohya T, Yanagawa T, Asayama M,

Hisatomi K, Teratani T, Fujita K, Yoneda M, Nakajima A. Rebleeding rate after

interventional therapy directed by capsule endoscopy in patients with obscure

gastrointestinal bleeding. BMC Gastroenterol. 2008 Apr 23;8(1):12 [Epub ahead of

print]

128.Endo H, Kondo Y, Inamori M, Ohya TR, Yanagawa T, Asayama M, Hisatomi K,

Teratani T, Yoneda M, Nakajima A, Matsuhashi N. Ingesting 500 ml of

Polyethylene Glycol Solution During Capsule Endoscopy Improves the Image

Quality and Completion Rate to the Cecum. Dig Dis Sci. 2008 Dec;53(12):3201-5.

129.Yoneda M, Nozaki Y, Endo H, Fujita K, Nakajima A. Reply to "High-sensitivity

C-reactive protein and metabolic syndrome (insulin resistance syndrome) including

nonalcoholic steatohepatitis". J Gastroenterol. 2008;43(4):313. Epub 2008 May 6.

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130. Hotta K, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I,

Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto

M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H,

Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y.

Variations in the FTO gene are associated with severe obesity in the Japanese. J

Hum Genet. 2008;53(6):546-53. Epub 2008 Apr 1.

131.Tachibana M, Tezuka C, Muroi S, Nishimoto S, Katsumoto T, Nakajima A,

Kitabayashi I, Taniuchi I. Phosphorylation of Runx1 at Ser249, Ser266, and Ser276

is dispensable for bone marrow hematopoiesis and thymocyte differentiation.

Biochem Biophys Res Commun. 2008;368(3):536-42. 2.855

132. Tachibana M, Wada K, Katayama K, Kamisaki Y, Maeyama K, Kadowaki,T,

Blumberg RS, Nakajima A. Activation of peroxisome proliferator-activated receptor

g suppresses mast cell maturation involved in allergic disease. Allergy. 2008

Sep;63(9):1136-47, 5.334

133. Nakajima A, Fujisawa T, Fujisawa N, Takahashi H, Ikeda I, Tmimoto A,

Yonemitu K, Nakajima N, Wada K, Nakagama H, Blumberg RS. PPARg suppresses

colonic epithelial cell turnover and colon carcinogenesis through inhibition of the

b-catenin/TCF pathway. Journal of Pharmacological Science. 2008

Apr;106(4):627-38 [First Author Equal Contributed]. 2.242

134. Mawatari H, Kirikoshi H, Yoneda M, Higurashi T, Fujita K, Saito S, Inamori M,

Takahashi H, Abe Y, Kubota K, Nakajima A. Effective treatment for advanced

hepatocellular carcinoma with portal venous invasion using a combination therapy

of intra-arterial 5-fluorouracil and subcutaneous pegylated-interferon-alpha-2b.

Hepato-Gastroenterology 2008 Sep-Oct;55(86-87):1776-7.

135. Kubota K, Kakuta Y, Inayama Y, Yoneda M, Abe Y, Inamori M, Kirikoshi H, Saito

S, Nakajima A, Sugimori K, Matuo K, Kazunaga T, Shimada H. Clinicopathological

study of resected cases with primary carcinoma of the cystic duct.

Hepato-Gastroenterology. 2008 Jul-Aug;55(85):1174-8.

136. Tsuzawa K, Fujisawa N, Sekino Y, Suzuki K, Saito K, Koyama S, Tanaka M, Wada

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A, Inamori M, Kubota K, Nakajima A. EDUCATION AND IMAGING

Gastrointestinal: Intestinal spirochetosis. J Gastroenterol Hepatol. 2008 Jul;23(7 Pt

1):1160.

137. Endo H, Matsuhashi N, Inamori M, Ohya T, Yanagawa T, Asayama M, Hisatomi K,

Teratani T, Fujita K, Yoneda M, Nakajima A. Tumorous arteriovenous malformation

in the jejunum missed by capsule endoscopy. Gastrointestinal Endoscopy. 2008

Oct;68(4):773-4; discussion 774.

138. Ikeda T, Inamori M, Fujisawa N, Iwasaki T, Akiyama T, Akimoto K, Mawatari H,

Iida H, Endo H, Nozaki Y, Sakamoto Y, Fujita K, Takahashi H, Yoneda M, Yoneda K,

Goto A, Abe Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Nakajima A. Effects of

body positions on gastric emptying with enteral nutrition: a crossover study using a

continuous real time 13C breath test (BreathID system). Hepato-Gastroenterology.

2008 Sep-Oct;55(86-87):1905-7.

139. Iida H, Inamori M, Akimoto K, Mawatari H, Endo H, Nozaki Y, Akiyama T, Ikeda

T, Sakamoto Y, Fujita K, Yoneda K, Takahashi H, Yoneda M, Goto A, Abe Y,

Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima A. Early effects of

intravenous administrations of lansoprazole and famotidine on intragastric pH.

Hepato-Gastroenterology. Accepted in 2008. 2009 Mar-Apr;56(90):551-4.

140. Akiyama T, Inamori M, Akimoto K, Iida H, Mawatari H, Endo H, Nozaki Y, Yoneda

K, Ikeda T, Sakamoto Y, Fujita K, Yoneda M, Takahashi H, Goto A, Hirokawa S, Abe

Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Rino Y, Nakajima A. Gastric

surgery is not a risk factor for the development or progression of Barrett’s

epithelium. Hepato-Gastroenterology. 2008 Sep-Oct;55(86-87):1899-904.

141. Suzuki K, Takahashi H, Fujisawa N, Sekino Y, Akimoto K, Tomimoto A, Saito K,

Yoneda M, Inamori M, Abe Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Koyama

S, Nakajima A. Gastric ulcer following a thrombotic aneurism of the splenic artery.

Endoscopy. 2008 Aug;40 Suppl 2:E193-4..

142. Kobayashi N, Kirikoshi H, Higurashi T, Iida H, Mawatari H, Endo H, Nozaki Y,

Yoneda K, Akiyama T, Fujita K, Yoneda M, Takahashi H, Abe Y, Inamori M, Kubota

K, Saito S, Ueno N, Nakajima A. Tumor fragment impacted at the major duodenal

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papilla causing obstructive jaundice in a patient with hepatocellular carcinoma

(HCC). Gastrointestinal Endoscopy. 2008 Nov;68(5):999-1000; discussion 1000.

143. Fujita K, Nozaki Y, Yoneda M, Wada K, Takahashi H, Kirikoshi H, Inamori M,

Saito S, Iwasaki T, Terauchi Y, Maeyama S, Nakajima A. Nitric oxide plays a

crucial role in the development/progression of nonalcoholic steathepatitis (NASH) in

the choline deficient, l-amino acid-deficient (CDAA) diet-fed rat model. Alcohol Clin

Exp Res. 2008 Oct 30. [Epub ahead of print], 2010 Feb;34 Suppl 1:S18-24. Epub

2009 Nov 5.

144. Yoneda K, Tomimoto A, Endo H, Iida H, Sugiyama M, Takahashi H, Nozaki Y,

Fujita K, Yoneda M, Inamori M, Nakajima N, Wada K, Nagashima Y, Nakagama H,

Nakajima A. Expression of Adiponectin receptors, AdipoR1 and AdipoR2, in normal

colon epithelium and colon cancer tissue. Oncology Reports, 2008; 20 (3): 479-83.

145. Kobayashi N, Higurashi T, Iida H, Mawatari H, Endo H, Nozaki Y, Tomimoto A,

Yoneda K, Akiyama T, Koji F, Takahashi H, Yoneda M, Abe Ysunobu, Kirikoshi H,

Kubota K, Saito S, Ueno N, Nakajima A, Yamanaka S, Inayama Y.

Adenosequamous carcinoma of pancreas associated with Humoral Hypercalcemia of

Malignancy (HHM). J Hepatobiliary Pancreat Surg. 2008;15(5):531-5, 1.182

146. Fujita K, Nozaki Y, Yoneda M, Wada K, Endo H, Mawatari H, Takahashi H,

Inamori M, Abe Y, Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima A.

Effectiveness of antiplatelet drugs on experimental non-alcoholic fatty liver disease.

Gut. 2008;57(11):1583-91..

147. Nakajima A, Tomimoto A, Fujita K, Sugiyama M, Takahashi H, Ikeda I, Hosono K,

Endo H, Yoneda K, Iida H, Inamori M, Kubota K, Saito S, Nakajima N, Wada K,

Nagashima Y, Nakagama H. Inhibition of Peroxisome Proliferator-Activated

Receptor Gamma Activity Suppresses Pancreatic Cancer Cell Motility.

Cancer Science. 2008;99 (10):1892-900.

148. Akiyama T, Inamori M, Akimoto K, Iida H, Mawatari H, Endo H, Nozaki Y,

Yoneda K, Sakamoto Y, Ikeda T, Fujita F, Yoneda M, Takahashi H, Goto A, Abe Y,

Kirikoshi H, Kobayashi N, Kubota K, Saito S, Nakajima A. Gender differences in

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the age-stratified prevalence of erosive esophagitis and Barrett’s epithelium in

Japan. Hepato-gastroenterology. 56(89):144-8. 2009

149. Suzuki K, Kawabe T, Takahashi H, Nakao S, Suzuki A, Inamori M, Iida H, Endo

H, Akiyama T, Fujita K, Yoneda M, Abe Y, Kobayashi N, Kubota K, Oshiro H,

Nakajima A. Collagenous colitis in Japanese woman: successful treatment by

mesalazine. Digestion. 77(3-4):155-156. 2008

150. Suzuki K, Nakao S, Suzuki A, Inamori M, Iida H, Endo H, Akiyama T, Yoneda K,

Fujita K, Takahashi H, Yoneda M, Abe Y, Kobayashi N, Kubota K, Saito S,

Nakajima A. Ulcerative colitis with positivity for proteinase 3-antineutrophil

cytoplasmic antibody. Digestion. 77(3-4):157-158. 2008

151. Suzuki A, Yabushita Y, Takahashi H, Inamori M, Nakao S, Suzuki K, Iida H,

Endo H, Akiyama T, Ikeda T, Sakamoto Y, Fujita K, Yoneda M, Goto A, Abe Y,

Kirikoshi H, Kobayashi N, Kubota K, Saito S, Nakajima A. Education and Imaging.

Gastrointestinal: Ascaris lumbricoidosis manifested by gastrointesitinal bleeding. J

Gastroenterol Hepatol. 23(11):1770. 2008

152. Yoneda M, Endo H, Mawatari H, Nozaki Y, Fujita K, Akiyama T, Higurashi T,

Uchiyama T, Yoneda K, Takahashi H, Kirikoshi H, Inamori M, Abe Y, Kubota K,

Saito S, Kobayashi N, Yamaguchi N, Maeyama S, Yamamoto S, Tsutsumi S,

Aburatani H, Wada K, Hotta K, Nakajima A. Gene Expression Profiling of

Nonalcoholic Steatohepatitis (NASH) by Gene Set Enrichment Analysis (GSEA).

Hepatology Research. ;38(12):1204-12. 2008

153. Hotta K, Nakamura M, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R,

Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S,

Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T,

Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani

N, Nakamura N. INSIG2 gene rs7566605 polymorphism is associated with severe

obesity in the Japanese. J Hum Genet.;53 (9):857-62. 2008

154. Inamori,M, Iida H, Endo H, Hosono K, Akiyama T, Yoneda K, Fujita K, H Iwasaki,

Takahashi H, Yoneda M, Goto A, Abe Y, Kobayashi N, Kubota K, Nakajima A.

Aperitif effects on gastric emptying: a crossover study using continuous real time

13C breath test (BreathID system). Dig Dis Sci. 54(4):816-8. 2009

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155.Abe Y, Inamori M, Uchiyama T, Iida H, Akimoto K, Mawatari H, Nozaki Y, Hosono

K, Endo H, Akiyama T, Yoneda K, Fujita K, Yoneda M, Takahashi H, Goto A,

Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima A. Gastrointestinal:

Aneurysmal artery in a gastric ulcer following endoscopic hemostasis. J

Gastroenterol Hepatol ;24(2):323. 2009

156. Yoneda M, Hotta K, Nozaki Y, Endo H, Uchiyama T, Mawatari H, Iida H, Kato K,

Hosono K, Fujita K, Yoneda K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M,

Abe Y, Kubota K, Saito S, Maeyama S, Wada K, Nakajima A. Association between

PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease

(NAFLD). BMC Gastroenterology. ;8(1):27. 2008

157. Hosono K, Endo H, Inamori M, Mawatari H, Iida H, Nozaki Y, Yoneda K, Akiyama

T, Fujita K, Yoneda M, Takahashi H, Abe Y, Kirikoshi H, Kobayashi N, Kubota K,

Saito S, Nakajima A. Severe large-intestine involvement in adult-onset

Henoch-Schonlien purpura: Successful treatment with factor XIII concentrate.

Digestion.;78(1):9. 2008

158.Kitai Y, Takahashi H, Goto A, Iida H, Mawatari H, Fujita K, Yoneda M , Inamori M,

Abe Y, Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima A.

Chemotherapeutic treatment of priapism in metastatic rectal cancer Case Reports

in Gastroenterology ;2:505-508. 2008

159.Hattori Y, Higurashi T, Takahashi H, Inamori M, Abe Y, Rino Y, Nakajima A.

Gastric varices with remarkable collateral veins in valpronic acid induced chronic

pancreatitis. Case Reports in Gastroenterology ;2:279-282.2008

160.Hattori Y, Kobayashi S, Takahashi H, Yoneda M, Inamori M, Abe Y, Kubota K,

Saito S, Nakajima A. Gastric inflammatory fibroid polyp treated by endoscopic

submucosal dissection. Case Reports in Gastroenterology 2008 Aug 19;2(2):283-6.

doi: 10.1159/000151330.

161. Endo H, Matsuhashi N, Inamori M, Ohya T, Iida H, Mawatari H, Nozaki Y,

Yoneda K, Akiyama T, Fujita K, Takahashi H, Yoneda M, Abe Y, Kobayashi N,

Kirikoshi H, Kubota K, Saito S, Nakajima A. Abdominal surgery affects small

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bowel transit time and completeness of capsule endoscopy. Dig Dis Sci..

54(5):1066-70. 2009

162. Tomimoto A, Endo H, Sugiyama M, Fujisawa T, Hosono K, Takahashi H,

Nakajima N, Nagashima Y, Wada K, Nakagama H, Nakajima A. Metformin

suppresses intestinal polyp growth in ApcMin/+ mice. Cancer Science ;99

(11):2136-41. 2008

163. Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M,

Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K,

Nakagama H, Nakajima A. Adiponectin Suppresses Colorectal Carcinogenesis

under the High-fat Diet Condition. Gut ;57 (11):1531-8. 2008

164. Shimamura T, Fujisawa T, Husain SR, Kioi M, Nakajima A, Puri RK. Novel role

of IL-13 in fibrosis induced by Non-Alcoholic Steotohepatitis and its amelioration by

IL-13 Receptor Directed Cytotoxin in a rat model. J Immunol ;181 (7):4656-65

2008

165. Kubota K, KatoS, Akiyama T, Yoneda M, Fujita K, Ogawa M, Inamori M,

Kobayashi N, Saito S, Kakuta Y, Ohshiro H, Nakajima A. Differentiating Sclerosing

Cholangitis Caused by Autoimmune Pancreatitis and Primary Sclerosing

Cholangitis According to Endoscopic Duodenal Papillary Features. Gastrointestinal

Endoscopy. ;68:1204-1208. 2008

166. Abe Y, Inamori M, Iida H, Endo H, Akiyama T, Yoneda K, Fujita K, Takahashi T,

Yoneda M, Hirokawa S, Goto A, Kirikoshi H, Kobayashi N, Kubota K, Saito S,

Nakajima A. Clinical characteristics of patients with gastric perforation following

endoscopic submucosal resection for gastric cancer. Hepatogastroenterology.

56(91-92):921-4. 2009

167.Akimoto K, Inamori M, Iida H, Endo H, Akiyama T, Ikeda T, Fujita K, Takahashi H,

Yoneda M, Goto A, Abe Y, Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima

A. Does postprandial coffee intake enhance gastric emptying?: a crossover study

using continuous real time 13C breath test (BreathID system).

Hepatogastroenterology. 56(91-92):918-20. 2009

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168.Akiyama T, Inamori M, Akimoto K, Iida H, Mawatari H, Endo H, Ikeda T, Nozaki Y,

Yoneda K, Sakamoto Y, Fujita K, Yoneda M, Takahashi H, Hirokawa S, Goto A, Abe

Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Nakajima A. Risk Factors for the

Progression of Endoscopic Barrett’s Epithelium in Japan: A Multivariate Analysis

Based on The Prague C & M Criteria. Dig Dis Sci. 2009 Aug;54(8):1702-7. Epub

2008 Nov 12.

169.Sugiyama M, Takahashi H, Hosono K, Endo H, Kato S, Yoneda k, Nozaki Y, Fujita

K, Yoneda M, Wada K, Nakagama H, Nakajima A. Adiponectin inhibits colorectal

cancer cell growth through the AMPK/mTOR pathway. Int J Oncol. 34(2):339-44.

2009

170.Takahashi H, Takayama T, Yoneda K, Endo H, Nozaki Y, Fujita K, Yoneda M,

Inamori M, Abe Y, Kobayashi N, Kirikoshi H, Kubota K, Saitoh S, Nakagama H,

Nakajima A. Association of visceral fat accumulation and plasma adiponectin with

rectal dysplastic aberrant crypt foci in a clinical population. Cancer Science

100(1):29-32. 2009

171. Fujisawa T, Sugiyama M, Tomimoto A, Wada K, Endo H, Takahashi H, Yoneda K,

Yoneda M, Inamori M, Saito S, Terauchi Y, Kadowaki T, Tsuchiya N, Nakagama H,

Nakajima A. Inhibition of peroxisome proliferator-activated receptor g promotes

tumorigenesis through activation of the b-catenin/TCF pathway in the mouse

intestine. J Parmacological Sci. 108(4):535-44. 2008

172. Yoneda M, Uchiyama T, Kato S, Endo H, Fujita K, Yoneda K, Mawatari H, Iida H,

Takahashi H, Kirikoshi H, Inamori M, Nozaki Y, Kobayashi N, Kubota K, Saito S,

Maeyama S, Sagara M, Aburatani H, Kodama T, Nakajima A. Plasma Pentraxin3

is a Novel Marker for Nonalcoholic Steatohepatitis (NASH). BMC Gastroenterol.

8(1):53. 2008Epub ahead of print]

173. Endo H, Hosono K, Inamori M, Kato S, Yoneda K, Akiyama T, Fijita K, Takahashi

H, Yoneda M, Abe Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Matsuhshi N,

Nakajima A. Incidence of small bowel injury induced by low-dose aspirin: a

crossover study using capsule endoscopy in healthy volunteers. Digestion.

79(1):44-51. 2009 [Epub ahead of print]

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174. Inaba H, Hokamura K, Nakano K, Nomura R, Katayama K, Nakajima A, Yoshioka

H, Taniguchi K, Kamisaki Y, Ooshima T, Umemura K, Murad F, Wada K, Amano A.

Upregulation of S100 calcium-binding protein A9 is required for induction of smooth

muscle cell proliferation by a periodontal pathogen. FEBS Lett. 583(1):128-34. 2009

175. Oshiro H, Matsuo K, Mawatari H, Inayama Y, Yamanaka S, Nagahama K, Endo

I, Shimada H, Nakajima A, Kubota K. Mucin-producing gallbladder

adenocarcinoma with focal small cell and large cell neuroendocrine differentiation

associated with pancreaticobiliary maljunction. Pathol Int. ;58(12):780-6. 2008

176. Kirikoshi H, Saito S, Yoneda M, Fujita K, Mawatari H, Uchiyama T, Higurashi T,

Goto A, Takahashi H, Abe Y, Inamori M, Kobayashi N, Kubota K, Sakaguchi T,

Ueno N, Nakajima A. The outcome of transarterial chemoembolization (TACE)

monotherapy and combined TACE with percutaneus ethanol injection (PEI) or

radiofrequency ablation (RFA) therapy for hepatocellular carcinoma (HCC).

Hepatology Research. 39(6):553-62. 2009

177. Nagaishi T, Chen Z, Chen L, Iijima H, Nakajima A, Blumberg RS. CEACAM1

and the regulation of mucosal inflammation. Mucosal Immunol. 2008 Nov;1 Suppl

1:S39-42.

178. Nakajima A, Takahashi H, Inamori M, Abe Y, Kobayashi N, Kubota K, Yamanaka

S. Anaplastic carcinoma of the pancreas producing granulocyte-colony stimulating

factor: a case report. J Med Case Reports. 2(1):391. 2008 [Epub ahead of print]

179. Akiyama T, Inamori M, Iida H, Mawatari H, Endo H, Hosono K, Yoneda K, Fujita

K, Yoneda M, Takahashi H, Goto A, Abe Y, Kobayashi N, Kubota K, Saito S,

Nakajima A. Alcohol consumption is associated with an increased risk of erosive

esophagitis and Barrett's epithelium in Japanese men. BMC Gastroenterol.

8(1):58. 2008

180.Yoneda M, Hotta K, Nozaki Y, Endo H, Uchiyama T, Mawatari H, Iida H, Kato S,

Fujita K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M, Abe Y, Kubota K,

Saito S, Maeyama S, Wada K, Nakajima A. Association between angiotensin II

type 1 receptor (AGTR1) polymorphisms and the occurrence of nonalcoholic fatty

liver disease (NAFLD) Liver International. 29(7):1078-85. 2009

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181.Yumori A, Okubo H, Takahashi H, Iida H, Mawatari H, Yoneda M, Inamori M, AbeY,

Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima A. Education and imaging.

Gastrointestinal: mantle cell lymphoma diagnosed by balloon enteroscopy. J

Gastroenterol Hepatol. 23(10):1623. 2008

182.Endo H, Hosono K, Inamori M, Nozaki Y, Yoneda K, Fujita K, Takahashi H, Yoneda

M, Abe Y, Kirikoshi H, Kobayashi N, Kubota K, Saito S, Ohya T, Hisatomi K,

Teratani T, Matsuhashi N, Nakajima A Characteristics of small bowel injury in

symptomatic chronic low-dose aspirin users: the experience of two medical centers

in capsule endoscopy J. Gastroenterology 44(6):544-9. 2009

183.Saito K, Inamori M, Sekino Y, Akimoto K, Suzuki K, Tomimoto A, Fujisawa N,

Kubota K, Saito S, Koyama S, Nakajima A. Management of acute lower intestinal

bleeding: what bowel preparation should be required for urgent colonoscopy?

Hepatogastroenterology. 2009 Sep-Oct;56(94-95):1331-4.

184.Mawatari H, Inamori M, Fujita K, Yoneda M, Iida H, Endo H, Hosono K, Nozaki Y,

Yoneda K, Akiyama T, Takahashi H, Goto A, Abe Y, Kirikoshi H, Kobayashi N,

Kubota K, Saito S, Nakajima A. The continuous real-time 13C-octanoate breath test

for patients with nonalcoholic steatohepatitis using the BreathID system.

Hepatogastroenterology. 2009 Sep-Oct;56(94-95):1436-8.

185.Okada K, Inamori M, Imajo K, Chiba H, Nonaka T, Shiba T, Sakaguchi T, Atsukawa

K, Takahashi H, Hishino E, Nakajima A. Clinical study of gastroduodenal disorders

associated with Low-dose aspirin in Japanese patients. Hepatogastroenterology.

2009 Nov-Dec;56(96):1665-9.

186. Kobayashi N, Mawatari H, Kubota K, Nakajima A. Intraductal ultrasonography in

von Hippel- Lindau disease. Gastrointestinal Endoscopy 2009 Jun;69(7):1384-5;

discussion

187.Kobayashi N, Kubota K, Nakajima A. Hepatic artery pseudoaneurysm associated

with cholangitis that ruptured into the bile duct. Clinical Gastroenterology and

Hepatology. 2009 Aug;7(8):e45.

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188.Uchiyama T, Inamori M, Iida H, Endo H, Hosono K, Akiyama T, Yoneda K, Fujita K,

Takahashi H, Yoneda M, Goto A, Abe Y, Kirikoshi H, Kobayashi N, Kubota K, Saito

S, Nakajima A. Preparation with oral tablets of sodium phosphate (Visiclear®) is

suitable for colonoscopy but not suitable for colonoscopy with upper endoscopy.

Digestion. 79(2):98. 2009

189.Hotta K, Nakamura T, Takasaki J, Takahashi H, Takahashi A, Nakata Y,

Kamohara S,Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H,

Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K,

Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T,

Matsuzawa Y, Kamatani N, Nakamura Y. Screening of 336 Single Nucleotide

Polymorphisms (SNPs) in 85 Obesity-Related Genes Revealed McKusick-Kaufman

Syndrome (MKKS) Gene Variants are Associated with Metabolic Syndrome. J

Human Genet 54(4):230-5. 2009

190.Kawakami Y, Takahashi H, Mawatari H, Taniguchi L, Hosono K, Endo H, Yoneda K,

Inamori M, Abe Y, Nakajima A. Gastric variceal rupture successfully treated with

repeated EIS and EVL Hepatogastroenterology 2010 Mar-Apr;57(98):377-8.

191.Yoneda M, Nozaki Y, Endo Y, Mawatari H, Iida H, Fujita H, Yoneda K, Takahashi H,

Kirikoshi H, Inamori M,Kobayashi N,Kubota K,Saito S,Maeyama S, Hotta K,

Nakajima A. Serum ferritin is a clinical biomarker in Japanese patients with

nonalcoholic steatohepatitis (NASH) independent of HFE gene mutation. Digestive

Diseases and Sciences. 2010 Mar;55(3):808-14. Epub 2009 Mar 7.

192.Akiyama T, Endo H, Inamori M, Iida H, Hosono K, Fujita K, Yoneda M, Takahashi

H, Goto A, Abe Y, Kirikoshi H, Kobayashi N,Kubota K, Saito S, Nagahama K,

Inayama Y, Nakajima A. Symptomatic Gastric Sarcoidosis with Multiple Antral

Ulcers. Endoscopy. 2009;41 Suppl 2:E159. Epub 2009 Jun 19.

193.Uchiyama T, Takahashi H, Hosono K, Endo H, Akiyama T, Yoneda K, Inamori M,

Abe Y, Kubota K, Saito S, Nakajima A. Portal vein thrombosis treated using

danaparoid sodium and antithrombin III. Heaptogastroenterology. 2010

Jan-Feb;57(97):52-3.

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194.Endo H, Fujisawa T, Takahashi H, Inamori M, Nakajima A. Author response Gut

Accepted in 2009.2

195.Akiyama T, Inamori M, Shimamura T, Iida H, Endo H, Fujita K, Yoneda M,

Takahashi H, Abe Y, Kobayashi N, Kubota K, Kobayashi H, Yamanaka S, Rino Y,

Nakajima A. Penetration of the sigmoid colon to the posterior uterine wall

secondary to diverticulitis: A rare complication of diverticulitis. Journal of Medical

Case Reports 2009 Aug 24;3:8957. doi: 10.4076/1752-1947-3-8957.

196.Yoneda K, Iida H, Endo H, Hosono K, Akiyama T, Takahashi H, Inamori M, Abe Y,

Yoneda M, Fujita K, Kato S, Nozaki Y, Ichikawa Y, Uozaki H, Fukayama M,

Shimamura T, Kodama T, Aburatani H, Miyazawa C, Ishii K, Hosomi N, Sagara M,

Takahashi M, Ike H, Saito , Kusakabe A. Nakajima A Identification of Cystatin SN

as a novel tumor marker for colorectal cancer. International Journal of

Oncology 35(1):33-40. 2009

197.Akiyama T, Abe Y, Inamori M, Iida H, Endo H, Hosono K, Yoneda K, Takahashi H,

Ryo A, Yamanaka S, Inayama Y, Nakajima A. Endoscopic therapy using an

endoscopic variceal ligation for minute cancer of the esophagogastric junction

complicated with esophageal varices: a case report Journal of Medical Case Reports

2010 May 23;4(1):149.

198.Nozaki Y , Inamori M, Fujita K, Yoneda M, Uchiyama T, Kato S, Mawatari H, Iida H,

Hosono K, Endo H, Akiyama T, Yoneda K, Takahashi H, Goto G, Kobayashi N,

Kirikoshi H, Abe Y, Kubota K, Saito S, Kurai H, Yamanaka S, Nakajima A.

Asymptomatic hepatic schistosomiasis detected by ultrasonograpy and confirmed by

liver biopsy. Intern Med. 48(12):1109-10 2009

199.Hara H, Suzuki K, Sekino Y, Akimoto K, Tomimoto A, Akiyama T, Fujisawa N, Saito

K, Inamori M, Kubota K, Nakamura A, Saito S, Koyama S, Nakajima A. Colonic

ulcers in a patient taking low-dose aspirin. Digestion 2009;79(4):251. Epub 2009

May 4. No abstract available.

200.Akiyama T,Inamori M,Iida H, Endo H,Hosono K,Yoneda K,Fujita K,Yoneda

M,Takahashi H,Goto A,Abe Y, Kirikoshi H,Kobayashi N,Kubota K,Saito S,Rino Y,

Nakajima A. Macroscopic Extent of Gastric Mucosal Atrophy: Increased Risk Factor

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for Esophageal Squamous Cell Carcinoma in Japan. BMC gastroenterology, 9:34.

2009

201.Yoneda M, Hotta K, Nozaki Y, Endo H, Tomeno W, Watanabe S, Hosono K,

Mawatari H, Iida H,Fujita K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M,

Kubota K, Shimamura T, Saito S, Maeyama S, Wada K, Nakajima A: Influence of

iNOS polymorphisms in Japanese patients with nonalcoholic fatty liver. Hepatology

Research, 2009 Oct;39(10):963-71. Epub 2009 Jul 13.

202.Takahashi H, Takayama T, Hosono K, Yoneda K, Endo H, Nozaki Y, Fujita K,

Yoneda M, Inamori M, Abe Y, Kobayashi N, Kirikoshi H, Kubota K, Saito S,

Nakagama H, Nakajima A. Correlation of the plasma level of insulin-like growth

factor-1 with the number of aberrant crypt foci in male individuals. Mol Med Rep. 2:

339-343. 2009

203.Ohata K, Niinami C, Ohya T, Inamori M, Nakajima A, Kurose N, Yashiro K:

EDUCATION AND IMAGING Pachydermoperiostosis with Crohn’s disease. J

Gastroenterol Hepatol. 2009 Sep;24(9):1576.

204. Kirikoshi H, Saito S, Yoneda M, Fujita K, Mawatari H, Uchiyama T, Higurashi

T,Imajo K, Sakaguchi T, Atsukawa K, Sawabe A, Kanesaki A, Takahashi H, Abe

Y,Inamori M, Kobayashi N, Kubota K, Ueno N, Nakajima A. Outcomes and factors

influencing survival in cirrhotic cases with spontaneous rupture of hepatocellular

carcinoma: a multicenter study. BMC Gastroenterol. 9:29. 2009 Apr 30

205.Fujita K, Nozaki Y, Wada K, Yoneda M, Fujimoto Y, Fujitake M, Endo H, Takahashi

H, Inamori M, Kobayashi N, Kirikoshi H, Kubota K, Saito S, Nakajima

A. Dysfunctional VLDL synthesis and release is a key factor in non-alcoholic

steatohepatitis (NASH) pathogenesis. Hepatology 2009 Sep;50(3):772-80.

206.Nozaki Y, Fujita K, Yoneda M, Wada K, Shinohara Y, Takahashi H, Kirikosh Hi,

Inamori M, Kubota K, Saito S, Mizoue T, Masaki N, Nagashima Y, Terauchi Y,

Nakajima A. Long-term combination therapy of ezetimibe and acarbose for

non-alcoholic fatty liver disease Journal of Hepatology 2009 Sep;51(3):548-56.

Epub 2009 Jun 6.

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207.Nagata M, Wada K, Nakajima A, Nakajima N, Kusayama M, Masuda T, Iida S,

Okura M, Kogo M, Kamisaki Y, Role of Myeloid Cell Leukemia-1 on Cell Growth of

Squamous Cell Carcinoma. journal of pharmacological science 110(3):344-53 2009

208.Mawatari H, Yoneda M, Fujita K, Nozaki Y, Shinohara Y, Sasaki H, Iida H,

Takahashi H, Inamori M, Abe Y, Kobayashi N, Kubota K, Kirikoshi H, Nakajima A,

Saito S. Association between lipoprotein subfraction profile and the response to

hepatitis C treatment in Japanese with genotype 1b. Journal of Viral Hepatitis 2010

Apr 1;17(4):274-9. Epub 2009 Aug 25.

209.Endo H, Hosono K, Fujisawa T, Takahashi H, Sugiyama M, Yoneda K, Nozaki Y,

Fujita K, Yoneda M, Inamori M, Wada K, Nakagama H, Nakajima A. Involvement of

JNK pathway in the promotion of the early stage of colorectal carcinogenesis under

high-fat dietary conditions. Gut. 2009 ;58(12):1637-43.

210.Fujisawa N, Inamori M, Endo H, Uchiyama T, hosono k, akiyama t, tomimoto a,

Koyama S, Sawabe a, Tanida e, Yanagisawa s, Hata Y, Okada k, Atsukawa K,

Watanabe S, Kawamura H, Higurashi T, Nagase H, Akimoto K, Matsuhashi N,

Nakajima A. Incidence of and Risk Factors for Upper Gastrointestinal

Complications in Patients Taking Low-dose Aspirin in Japan.

Hepatogastroenterology. accept in 2009.7. 2011 Jan-Feb;58(105):229-34.

211.Iida H, Inamori M, Nozaki Y, Endo H, Hosono K, Akiyama T, Sakamoto Y,

Takahashi H, Koide T, Tokoro C, Abe Y, Nakajima A. Early effects of oral

administration of lafutidine with mosapride compared with lafutidine alone on

intragastric pH values. BMC Gastroenterology 9(1):52.2009 [Epub ahead of print]

212.Suzuki K, Takahashi H, AbeY, Inamori M, Watanabe S, Koide T, Tokoro C, Iida H,

Hosono K, Endo H, Shimamura T, Kobayashi N, Kirikoshi H, Kubota K, Saito S,

Ono H, Akiyama H, Yazawa T, Nakajima A. A case of a peculiarly shaped

gastrointestinal stromal tumor (GIST) Endoscopy 2010;42 Suppl 2:E65-6. Epub

2010 Mar 1.

213.Akiyama T, Yoneda M, Inamori M, Iida H, Endo H, Hosono K, Yoneda K,Fujita K,

Koide T, Tokoro C, Takahashi H, Goto A, Abe Y, Kirikoshi H, Kobayashi N, Kubota

K, Saito S, Nakajima A, Visceral obesity and the risk of Barrett's esophagus in

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Japanese patients with non-alcoholic fatty liver disease BMC Gastroenterology

9(1):56.2009

214.Watanabe S, Takahashi H, Abe Y, Inamori M, Koide T, Tokoro C, Hosono K, Endo H,

Kobayashi N, Kirikoshi H, Kubota K, Saito S, Sugano N, Rino Y, Nakayama T,

Inayama Y, Nakajima A. Importance of MDCT for the diagnosis of small intestinal

tumor. Digestion 80(4) 247 2009 Oct 15

215.Kubota K, Kato S, Akiyama T, Fujita K, Yoneda M, Takahashi H, Ogawa M,

Inamori M, Abe Y, Kirikoshi H, Kobayashi N, Saito S, Hisatomi K, Matsuhashi N,

Nakajima A. A proposal for differentiation between early- and advanced-stage

autoimmune pancreatitis by endoscopic ultrasonography. Dig Endosc. 2009

Jul;21(3):162-9.

216.Nagasaki A, Takahashi H, Iinuma M, Uchiyama T, Watanabe S, Koide T, Tokoro C,

Inamori M, Abe Y, Nakajima A. Ulcerative colitis with multi-drug resistant

Pseudomonas aeruginosa infection successfully treated with Bifidobacterium

Digestion 81(3).2010:204-205. Epub 2010 Jan 19.

217.Sakamoto Y, Inamori M, Iida H, Hosono K, Endo H, Takahashi H, Koide T, Tokoro C,

Abe Y, Kawana K, Hasagawa N, Kakuta Y, Nagase H, Nakajima A Esophageal

granular cell tumor treated by endoscopic mucosal resection Digestion accepted in

2009.9. 80(4): 258-259. 2009 Oct 15

218.Hara H, Sakai E, Inokuchi Y, Iida H, Endo H, Hosono K, Akiyama T, Sakamoto Y,

Takahashi H, Koide T, Tokoro C, Inamori M, Abe Y, Nakajima A. Dissecting

intramural hematoma of the esophagus in a kendo player taking low-dose aspirin.

Internal Medicine 2009;48(24):2153-4.

219.Higurashi T, Takahashi H, Inamori M, Iida H, Hosono K, Endo H, Sakamoto Y,

Fujita K, Yoneda M, Koide T, Tokoro C, Abe Y, Kirikoshi H, Saito S, Yamanaka S,

Nakajima A. Intravascular lymphoma: usefulness of liver biopsy in clinical setting.

Internal Medicine 2009;48(24):2155-6.

220.Kawakami Y, Takahashi H, Kato S, Uchiyama T, Mawatari H, Iida H, Inamori M,

Abe Y, Nakajima A Effective treatment for duodenal variceal bleeding using

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endoscopic ligation Hepato-Gastroenterology accepted in 2009.9. 2011

Nov-Dec;58(112):2024-5.

221.Tokoro C, Inamori M, Koide T, Iida H, Sakamoto Y, Endo H, Hosono K, Takahashi H,

Yoneda M, Yasuzaki H, Ogawa M, Abe Y, Kubota K, Saitou S, Kawana I, Matsuda R,

Takahashi D, Nakajima A. Does pretreatment with proton pump inhibitors

influence the eradication rate of Helicobacter pylori? Hepato-Gastroenterology

2010 Nov-Dec;57(104):1645-9.

222.Uchiyama T, Inamori M, Iida H, Endo H, Hosono K, Akiyama T, Takahashi H,

Koide T, Tokoro C, Yoneda M, Fujita K, Goto A, Abe Y, Kobayashi N, Kirikoshi H,

Shimamura T, Kubota K, Saito S, Nakajima A. Renal Dysfunction Caused by Oral

Sodium Phosphate Tablets for Colonoscopy. Digestion. 2009 Sep 16;80(3):159.

223.Kato S, Inoue S, Inamori M, Miyazawa N, Sato T, Kobayashi N, Mishina K, Sasaki

M, Nakajima A, Ishigatsubo Y. Esophago-mediastinal and -bronchial fistulas

associated with invasive aspergillosis. Endoscopy. 2010;42 Suppl 2:E48-9. Epub

2010 Feb 15. accepted in 2009.10

224.Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake

N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M,

Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Ueno T,

Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao

K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y. Association between obesity

and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a

Japanese population. J Hum Genet. 2009 Dec;54(12):727-31. Epub 2009 Oct 23.

225.Mawatari H, Yoneda M, Fujita K, Nozaki Y, Shinohara Y, Sasaki H, Iida H,

Takahashi H, Inamori M, Abe Y, Kobayashi N, Kubota K, Kirikoshi H, Nakajima A,

Saito S. Association between phospholipids and free cholesterol in high-density

lipoprotein and the response to hepatitis C treatment in Japanese with genotype 1b.

J Viral Hepat. 2010 Dec;17(12):859-65.

226.Inaba K, Fukazawa Y, Matsuda K, Himeno A, Matsuyama M, Ibuki K , Miura Y,

Koyanagi Y, Nakajima A , Richard S.Blumberg , Takahashi H, Hayami M, Igarashi

T, Miura T. Small intestine CD4+ cell reduction and enteropathy in SHIV-1

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KS661-infected rhesus macaques in presence of low viral load. Journal of General

Virology 2010 Mar;91(Pt 3):773-81. Epub 2009 Nov 4.

227.Fujisawa T, Joshi B, Nakajima A, Puri RK. A Novel Role of Interleukin-13 Receptor

alpha 2 in Pancreatic Cancer Invasion and Metastasis. Cancer Res. 2009 Nov

15;69(22):8678-85. Epub 2009 Nov 3.

228.Kubota K, Wada T, Kato S, Mozaki Y, Yoneda M, Fujita K, Takahashi H, Inamori M,

Abe Y, Kobayashi N, Kirikoshi H, Saito S, Inayama Y, Nakajima A. Highly Active

State of Autoimmune Pancreatitis With Mikulicz Disease. Pancreas. 2010

Jan;39(1):e6-10.

229.Chiba H, Ohata K, Ohno A, Sekino Y, Ito T, Tsuji Y, Ohya T, Inamori M, Nakajima A,

Matsuhashi N. A case of perforation with retroperitoneal emphysema after

endoscopic submucoal dissection for a rectal carcinoid tumor. Endoscopy 2010;42

Suppl 2:E85-6. Epub 2010 Mar 1.

230.Akiyama T, Inamori M, Iida H, Endo H, Hosono K, Sakamoto Y, Fujita K, Yoneda M,

Takahashi H, Koide T, Tokoro C, Goto A, Abe Y, Shimamura T, Kobayashi N, Kubota

K, Saito S, Nakajima A. The shape of Barrett’s epithelium is associated with

prevalence of erosive esophagitis. World J Gastroenterol. 2010 Jan 28;16(4):484-9.

231.Akiyama T, Inamori M, Akimoto K, Iida H, Endo H, Hosono K, Ikeda T, Sakamoto Y,

Fujita K, Yoneda M, Koide T, Takahashi H, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kubota K, Saito S, Moriya A, Rino Y, Imada T, Nakajima A. Gastric Surgery Is Not a

Risk Factor for Erosive Esophagitis or Barrett’s Esophagus. Scand J Gastroenterol.

2010 Apr;45(4):403-8.

232.Sakamoto Y, Inamori M, Iwasaki T, Iida H, Endo H, Hosono K, Ikeda T, Takahashi

H, Koide T, Tokoro C, Goto A, Abe Y, Shimamura T, Kirikoshi H, Kobayashi N,

Kubota K, Saito S, Nakajima A. Relationship between upper gastrointestinal

symptoms and diet therapy: Examination using Frequency Scale for the Symptoms

of GERD. Hepatogastroenterology. 2010 Nov-Dec;57(104):1635-8.

233.Yoneda M, Nozaki Y, Fujita K, Kirikoshi H, Saito S, Terauti Y, Nakajima

A. Efficacy of Ezetimibe for the Treatment of Nonalcoholic Steatohepatitis (NASH):

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An Open-label, Pilot Study Hepatology Research 2010 Jun;40(6):613-21. Epub 2010

Apr 14.

234.Suzuki K, Kirikoshi H, Yoneda M, Mawatari H, Fujita K, Nozaki Y, Takahashi H,

Abe Y, Inamori M, Shimamura T, Kobayashi N, Kubota K, Saito S, Nakajima A

Measurement of spleen volume is useful for distinguishing between simple steatosis

and early-stage nonalcoholic steatohepatitis Hepatology Research 2010 Jul

1;40(7):693-700.

235.Nozaki Y, Inamori M, Fujita K, Yoneda M, Kato S, Uchiyama T, Suzuki K,

Watanabe S, Mawatari H, Iida H, Hosono K, Endo H, Sakamoto Y, Yoneda K,

Takahashi H, Koide T, Tokoro C, Kobayashi N, Kirikoshi H, Shimamura T, Abe Y,

Kubota K, Saito S, Oshiro H, Inayama Y, Nakajima A. Metastatic tumor in the

colon from renal cell carcinoma. Internal Medicine. 2010;49(7):709.

236.Tokoro C, Inamori M, Uchiyama T, Iida H, Endo H, Hosono K, Sakamoto Y,

Takahashi H, Koide T, Goto A, Yasuzaki H, Abe Y, Matsuda R, Takahashi D,

Kawana I, Suzuki S, Nakajima A. Efficacy of granulocytapheresis (GCAP) for the

treatment of active ulcerative colitis and the avoidance of systemic corticosteroid

administration. Digestion. 2010 Feb 26;82(1):37-38.

237.Nozaki Y, Oshiro H, Nakajima A. Langerhans cell histiocytosis of the stomach

mimicking early gastric cance. Clin Gastroenterol Hepatol. 2010 Sep;8(9):A18.

Epub 2010 Feb 1.

238.Iida H, Inamori M, Uchiyama T, Endo H, Hosono K, Akiyama T, Sakamoto Y, Fujita

K, Takahashi H, Yoneda M, Koide T, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kirikoshi H, Kubota K, Saito S, Nakajima A. Early effects of oral administration of

lafutidine with peppermint oil, compared with lafutidine alone, on intragastric pH

values. Hepatogastroenterology. 2011 Jan-Feb;58(105):235-8.

239.Chiba H, Ohata K, Sekino Y, Ito T, Tsuji Y, Ohya T, Inamori M, Nakajima A,

Matsuhashi N. New technique for picking up large colorectal tumors during

endoscopic submucosal dissection. Digestion. 2010 Mar 5;82(1):66-67. in

press.Kirikoshi H, Saito S,Mawatari H, Yoneda M, Fujita K, Nozaki Y, Suzuki K,

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240.Takahashi H, Abe Y, Inamori M, Kobayashi N, Kubota K, Ueno N, Nakajima A:

Combined 5-fluorouracil and pegylated interferon α-2b therapy for advanced

hepatocellular carcinoma. Hepatogastroenterology accepted February 1, 2010.

241.Kirikoshi H, Saito S, Ueno N, Suzuki K, Takahashi H, Yoneda M, Fujita K,

Nakajima A: Evaluation of hepatocellular carcinoma with portal vein tumor

thrombosis by CEUS before and after hepatic arterial infusion chemotherapy.

Journal of Medical Ultrasonics 2010, Volume 37, Number 3, Pages 137-141

242.Kuriyama H, Kawana K, Taniguchi R, Jono F, Sakai E, Okubo H, Suzuki H,

Kobayashi S, Murata Y, Inamori M, Hata Y, Nakajima A. Single-agent gemcitabine

in elderly patients with unresectable biliary tract cancer. Hepatogastroenterology.

2010 in press. 2011 Jan-Feb;58(105):26-30.

243.Ito S, Oshima A, Inamori M, Uchiyama T, Iida H, Endo H, Hosono K, Sakamoto Y,

Fujita K, Yoneda M, Takahashi H, Koide T, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kubota K, Saito S, Nakajima A. Recurrent sigmoid volvulustreated by colonoscopic

reduction. Digestion. 2010 Jun 24;82(4):260.

244.Okada K, Inamori M, Imajo K, Chiba H, Nonaka T, Shiba T, Sakaguchi T,

Atsukawa K, Takahashi H, Hoshino E, Nakajima A. Gender differences of low-dose

aspirin-associated gastroduodenal ulcer in Japanese patients. A cross sectional

study. World J Gastroenterol. 2010 Apr 21;16(15):1896-900.

245.Asano Y, Morita Y, Iguchi K, Kasugai H, Inamori M, Uchiyama T, Iida H, Endo H,

Hosono K, Sakamoto Y, Fujita K, Yoneda M, Takahashi H, Koide T, Tokoro C, Goto A,

Abe Y, Kobayashi N, Kubota K, Nakajima A. Ulcerative colitis with Takayasu

disease. Digestion 2010 Jun 24;82(4):261.

246.Inamori M, Iida H, Hosono K, Endo H, Sakamoto Y, Takahashi H, Koide T, Tokoro C,

Goto A, Abe Y, Hiratsuka N, Nakajima A, Fujita M. The histamine H2 receptor

antagonist lafutidine in Japanese patients with nonerosive reflux disease.

Hepatogastroenterology 2010 Nov-Dec;57(104):1430-4.

247.Koide T, Inamori M, Kusakabe A, Uchiyama T, Watanabe S, Iida H, Endo H,

Hosono K, Sakamoto Y, Fujita K, Takahashi H, Yoneda M, Tokoro C, Yasuzaki H,

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Goto A, Abe Y, Kobayashi N, Kubota K, Saito S, Nakajima A. Early complications

following percutaneous endoscopic gastrostomy: Results of use of a new direct

technique. Hepatogastroenterology 2010 Nov-Dec;57(104):1639-44.

248.Oshima A, Ito S, Abe Y, Uchiyama T, Iida H, Endo H, Hosono K, Sakamoto Y,

Fujita K, Yoneda M, Takahashi H, Koide T, Tokoro C, Goto A, Inamori M,

Kobayashi N, Kubota K, Saito S, Nakajima A. Mesentric phlebosclerosis. Endoscopy.

2010;42 Suppl 2:E156-7. Epub 2010 Jun 16.

249.Hosono K, Endo H, Takahashi H, Sugiyama M, Uchiyama T, Suzuki K, Nozaki Y,

Yoneda K, Fujita K, Yoneda M, Inamori M, Tomatsu A, Chihara T, Shimpo

K,Nakagama H, Nakajima A. Metformin suppresses azoxymethane-induced

colorectal aberrant crypt foci by activating AMP-activated protein kinase. Molecular

Carcinogenesis. 2010 Jul;49(7):662-71.

250.Fujisawa N, Inamori M, Sekino Y, Akimoto K, Iida H, Takahata A, Endo H, Hosono

K, Sakamoto Y, Akiyama T, Koide T, Tokoro C, Takahashi H, Saito K, Abe Y,

Nakamura A, Kubota K, Saito S, Koyama S, Nakajima A. Risk Factors for Mortality

in Patients with Mallory-Weiss Syndrome. Hepatogastroenterology 2011

Mar-Apr;58(106):417-20.

251.Ohata K, Misaka R, Ito T, Chiba H, Tsuji Y, Yamawaki M, Ohya T, Inamori M,

Nakajima A, Matsuhashi N. Novel Endoscopic Technique for the Diagnosis of Early

Gastric Cancer: Endoscopy with crystal violet staining. Digestion. 2011 Feb

8;84(1):60-61.

252.Kasugai H, Asano Y, Iguchi K, Uchiyama T, Iida H, Endo H, Hosono K, Sakamoto Y,

Fujita K, Yoneda M, Takahashi H, Koide T, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kubota K, Maeda S, Nakajima A, Inamori M. Covered stent placement for duodenal

obstruction in pancreatic cancer. Digestion. 2011 Feb 1;83(4):296.

253. Kubota K, Kato S, Mawatari H, Iida H, Akiyama T, Fujita K, Yoneda M, Takahashi

H, Inamori M, Abe Y, Kirikoshi H, Kobayashi N, Saito S, Nakajima A. Risky

endoscopic ultrasonography-guided fine-needle aspiration for asymptomatic

retroperitoneal tumors. Dig Endosc. 2010 Apr;22(2):144-6.

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254.Fujisawa T, Nakashima H, Nakajima A, Joshi BH, Puri RK. Targeting

IL-13Ralpha2 in human pancreatic ductal adenocarcinoma with combination

therapy of IL-13-PE and gemcitabine. Int J Cancer. 2011 Mar 1;128(5):1221-31.

255.Yoneda M, Suzuki K, Kato S, Fujita K, Nozaki Y, Hosono K, Saito S, Nakajima A.

Nonalcoholic Fatty Liver Disease: US-based Acoustic Radiation Force Impulse

Elastography. Radiology. 2010 Aug;256(2):640-7. Epub 2010 Jun 7.

256. Nonaka T, Inamori M, Kessoku T, Ogawa Y, Imajyo K, Yanagisawa S, Shiba T,

Sakaguchi T, Nakajima A, Maeda S, Atsukawa K, Takahashi H. A case of acute

obstructive cholangitis caused by an enterolith in a duodenal diverticulum.

Endoscopy. 2010;42 Suppl 2:E204-5. Epub 2010 Sep 15.

257.Sekino Y, Fujisawa N, Suzuki K, Akimoto K, Tomimoto A, Miharada K, Koyama S,

Iida H, Endo H, Hosono K, Sakamoto Y, Takahashi H, Koide T, Tokoro C, Abe Y,

Maeda S, Nakajima A, Tatsumoto A, Sakurada H, Inamori M. A case of recurrent

infective endocarditis following colonoscopy. Endoscopy. 2010;42 Suppl 2:E217.

Epub 2010 Sep 15.

258.Sakamoto Y, Kato S, Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo H,

Fujita K, Koide T, Takahashi H, Yoneda M, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kubota K, Maeda S, Nakajima A, Inamori M. Effects of domperidone on gastric

emptying: a crossover study using a continuous real-time 13C breath test (BreathID

system). Hepatogastroenterology 2011 Mar-Apr;58(106):637-41.

259.Yoneda K, Takahashi H, Abe Y, Inamori M, Kato S, Uchiyama T, Iida H, Mawatari

H, Hosono K, Endo H, Nozaki Y, Akiyama T, Fujita K, Yoneda M, Kobayashi N,

Kirikoshi H, Kubota K, Saito S, Nakajima A. A mucosa-associated lymphoid tissue

(MALT) lymphoma of the small intestine that was difficult to diagnose

endoscopically. Endoscopy. 2010;42 Suppl 2:E175. Epub 2010 Jun 17.

260.Kato S, Kobayashi N, Kubota K, Kirikoshi H, Watanabe S, Ogawa M, Inamori M,

Shimamura T, Tomeno W, Nakajima A, Takeda K, Endo I, Nagashima Y, Aoki I. A

duodenal mucosal lesion coming from pancreatic arteriovenous malformation.

Gastrointest Endosc. 2010 Jun;71(7):1299-300.

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261.Ito S, Oshima A, Uchiyama T, Maeda S, Nakajima A, Inamori M. Hemolytic episode

following an upper gastrointestinal endoscopy in a patient with paroxysmal

nocturnal hemoglobinuria. Digestive Endoscopy. 2011 Jan;23(1):99

262.Uchiyama T, Goto A, sakai e, Sekino Y, Iida H, Endo H, Hosono K, Sakamoto Y,

Koide T, Takahashi H, Yoneda M, Tokoro C, abe y, shimamura T, Kobayashi N,

kubota k, Maeda S, Nakajima A, Ichikawa Y, Inamori M. Endoscopic hemostasis

through gastrostomy. Endoscopy. 2010;42 Suppl 2:E270. Epub 2010 Oct 7.

263.Nakajima A, Endo H, Yoneda K, Fujisawa T, Sugiyama M, Hosono K, Nozaki Y,

Takahashi H, Fujita K, Yoneda M, Inamori M, Shimamura T, Kobayashi N,

Kirikoshi H, Kubota K, Saito S, Wada K, Nakagama H,Molecular Mechanisms

Linking Adiponectin Receptor Signalling and Cancer. The Open Obesity Journal.

2010,2,43-49

264.Tokoro C, Inamori M, Koide T, Sekino Y, Iida H, Sakamoto Y, Endo H, Hosono K,

Takahashi H, Yoneda M, Yasuzaki H, Ogawa M, Abe Y, Kubota K, Saito S, Kawana I,

Nakajima A, Maeda S, Matsuda R, Takahashi D. Influence of pretreatment with H2

receptor antagonists on cure rates of Helicobacter pylori eradication. Medical

Science Monitor. 2011 May 2;17(5):CR235-240.

265.Kobayashi N, Niwa T, Kirikoshi H, Fujita K, Yoneda M, Saito S, Nakajima A.

Clinical classification of congenital extrahepatic portosystemic shunts.Hepatol Res.

2010 Jun;40(6):585-93.

266.Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake

N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A,

Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Masuzaki H, Ueno T,

Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao

K, Sakata T, Matsuzawa Y, Nakamura Y, Kamatani N. Polymorphisms in NRXN3,

TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in

the Japanese population. J Hum Genet. 2010 Nov;55(11):738-42. Epub 2010 Aug 12.

267.Kobayashi N, Kubota K, Kato S, Shimamura T, Kirikoshi H,Saito S, Ueda M, Endo

I, Inayama Y, Nakajima A FOXP3+ Regulatory T cells and Tumoral

Indoleamine 2,3-Dioxygenase Expression Predicts the Carcinogenesis of Intraductal

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Papillary Mucinous Neoplasms of the Pancreas. Pancreatology 2010 Nov

5;10(5):631-640.

268.Ohtake S, Kobayashi N, Kato S, Kubota K, Endo I , Inayama Y, Nakajima A

Duodenal gastrointestinal stromal tumor resembling a pancreatic neuroendocrine

tumor in a patient with neurofibromatosis type I (von Recklinghausen's disease): a

case report Journal of Medical Case Reports 2010 Sep 8;4(1):302.

269.Kobayashi N, Kubota K, Shimamura T, Watanabe S, Kato S, Suzuki K, Uchiyama T,

Maeda S, Takeda K, Nakajima A, Endo I, Complications of the Treatment of

Endoscopic Biliary Strictures Developing after Liver Transplantation. Journal of

Hepato-Biliary-Pancreatic Sciences 2011 Mar;18(2):202-10.

270.Okada K, Fujisaki J, Kasuga A, Omae M, Kubota M, Hirasawa T, Ishiyama A,

Inamori M, Chino A, Yamamoto Y, Tsuchida T, Nakajima A, Hoshino E, Igarashi M.

Sporadic non-ampullary duodenal adenoma in the natural history of duodenal

cancer: a study of follow-up surveillance. Am J Gastroenterol. 2011

Feb;106(2):357-64. Epub 2010 Dec 7.

271.Hosono K, Endo H, Takahashi H, Sugiyama M, Sakai E, Uchiyama T, Suzuki K,

Iida H, Sakamoto Y, Yoneda K, Koide T, Tokoro C, Abe Y, Inamori M, Nakagama H,

Nakajima A. Metformin suppresses colorectal aberrant crypt foci in a short-term

clinical trial. Cancer Prev Res (Phila). 2010 Sep;3(9):1077-83. Epub 2010 Sep 1.

272.Takahashi H, Hosono K, Uchiyama T, Sugiyama M, Sakai E, Endo H, Maeda S,

Schaefer KL, Nakagama H, Nakajima A. PPARgamma Ligand as a Promising

Candidate for Colorectal Cancer Chemoprevention: A Pilot Study. PPAR Res.

2010;2010. pii: 257835. Epub 2010 Aug 2.

273.Sekino Y, Iida H, Endo H, Sakamoto Y, Yoneda M, Koide T, Takahashi H, Tokoro C,

Abe Y, Nakajima A, Maeda S, Takihata M, Terauchi Y, Inamori M. Effectiveness of

repeated intragastric balloon therapy in a morbidly obese Japanese patient.

Internal Medicine 2011;50(2):109-12. Epub 2011 Jan 15.

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274.Akiyama T, Yoneda M, Maeda S, Nakajima A, Koyama S, Inamori M. Review

article: Visceral Obesity and the Risk of Barrett’s Esophagus. Digestion.

2011;83(3):142-5. Epub 2011 Jan 21.

275.Nonaka T, Kessoku T, Ogawa Y, Imajyo K, Yanagisawa S, Shiba T, Sakaguchi T,

Atsukawa K, Takahashi H, Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo

H, Sakamoto Y, Koide T, Takahashi H, Tokoro C, Abe Y, Maeda S, Nakajima A,

Inamori M. Does postprandial itopride intake affect gastric emptying?: a crossover

study using the continuous real time 13C breath test (BreathID system).

Hepatogastroenterology 2011 Jan-Feb;58(105):224-8.

276.Nakano K, Wada K, Nomura R, Nemoto H, Inaba H, Kojima A, Naka S, Hokamura

K, Mukai T, Nakajima A, Umemura K, Kamisaki Y, Yoshioka H, Taniguchi K,

Amano A, Ooshima T. Characterization of aortic aneurysms in cardiovascular

disease patients harboring Porphyromonas gingivalis Oral Dis. 2011

May;17(4):370-378. doi: 10.1111/j.1601-0825.2010.01759.x. Epub 2010 Oct 28.

277.Sakai E, Endo H, Tokoro C, Sugano N, Rino Y, Oshiro H, Nakajima A.

Cytomegalovirus-induced small-bowel bleeding detected by capsule endoscopy.

Gastrointest Endosc. 2011 May;73(5):1058-60. Epub 2010 Oct 29.

278.Endo H, Hosono K, Inamori M, Kato S, Uchiyama T, Iida H, Sakamoto Y, Fujita K,

Takahashi H, Koide T, Yoneda M, Tokoro C, Abe Y, Kubota K, Saito S, Nagahama K,

Inayama Y, Nakajima A. Capsule Endoscopic Evaluation of Eosinophilic Enteritis

before and after Treatment. Digestion. 2011;83(1-2):134-135. Epub 2010 Nov 1.

279.Uchiyama T, Takahashi H, Sugiyama M, Sakai E, Hosono K, Endo H, Yoneda K,

Yoneda M, Inamori M, Nagashima Y, Inayama Y, Wada K, Nakajima A. Leptin

receptor is involved in STAT3 activation in human colorectal adenoma. Cancer

Science. 2011 Feb;102(2):367-72. doi: 10.1111/j.1349-7006.2010.01803.x. Epub 2010

Dec 19.

280. Kubota K, Nakajima A, The therapeutic strategy for autoimmune pancreatitis is

subject to the endoscopic features of the duodenal papilla Therapeutic Advances in

Gastroenterology November 2010 3: 383-395, first published on May 4, 2010

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281. Kubota K, Kato S, Watanabe S, Fujita K, Yoneda M, Takahashi H, Inamori M,

Shimamura T, Kirikoshi H, Kobayashi N, Saito S, Hisatomi K, Matsuhashi N,

Nakajima A. Usefulness of endoscopic biopsy using FOXP3(+) Treg up-regulation in

the duodenal papilla in the differential diagnosis between autoimmune pancreatitis

and pancreatic cancer. J Hepatobiliary Pancreat Sci. 2011 May;18(3):414-21.

282.Hotta K, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Chayama K, Nakajima

A, Nakao K, Sekine A. Association of the rs738409 polymorphism in PNPLA3 with

liver damage and the development of nonalcoholic fatty liver disease. BMC Med

Genet. 2010 Dec 22;11(1):172. [Epub ahead of print]

283.Yoneda M, Fujita K, Imajo K, Mawatari H, Kirikoshi H, Saito S, Nakajima A.

Induction of microsomal triglyceride transfer protein expression is a candidate

mechanism by which ezetimibe therapy might exert beneficial effects in patients

with nonalcoholic steatohepatitis. J Gastroenterol. 2011 Mar;46(3):415-6. Epub 2010

Dec 22.

284.Kubota K, Kato S, Uchiyama T, Watanabe S, Nozaki Y, Fujita K, Yoneda M, Inamori

M, Shimamura T, Abe Y, Kirikoshi H, Kobayashi N, Saito S, Nakajima A.

Discrimination between sclerosing cholangitis-associated autoimmune pancreatitis

and primary sclerosing cholangitis, cancer using intraductal ultrasonography. Dig

Endosc. 2011 Jan;23(1):10-6. doi: 10.1111/j.1443-1661.2010.01039.x. Epub 2010 Nov

30.

285.Endo H, Hosono K, Higurashi T, Sakai E, Iida H, Sakamoto Y, Fujita K, Takahashi

H, Koide T, Yoneda M, Tokoro C, Inamori M, Abe Y, Matsuhashi N, Nakajima A.

Quantitative analysis of low-dose aspirin-associated small bowel injury using a

capsule endoscopy scoring index. Dig Endosc. 2011 Jan;23(1):56-61.

286.Yoneda M, Kato S, Mawatari H, Kirikoshi H, Imajo K, Fujita K, Endo H, Takahashi

H, Inamori M, Kobayashi N, Kubota K, Saito S, Tohnai I, Watanuki K, Wada K,

Maeda S, Nakajima A. Liver abscess caused by periodontal bacterial infection with

Fusobacterium necrophorum. Hepatol Res. 2011 Feb;41(2):194-6.

287.Sekino Y, Inamori M, Hirai M, Suzuki K, Tsuzawa K, Akimoto K, Tomimoto A,

Fujisawa N, Miharada K, Tsunemi A, Tanaka M, Iida H, Sakamoto Y, Takahashi H,

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Koide T, Tokoro C, Abe Y, Maeda S, Nakajima A, Koyama S. Solitary

Peutz-Jeghers-type hamartomatous polyp in the duodenum: Is it associated with a

low risk of cancer? J Med Case Reports 2011 Jun 27;5(1):240. [Epub ahead of print]

288.Fujita K, Imajo K, Shinohara Y, Nozaki Y, Wada K, Yoneda M, Endo H, Takahashi

H, Abe Y, Inamori M, Shimamura T, Kobayashi N, Kirikoshi H, Kubota K, Saito S,

Nakajima A. Novel Findings for the Development of Drug Therapy for Various Liver

Diseases:Liver Microsomal Triglyceride Transfer Protein Activator May Be a

Possible Therapeutic Agent in Non-alcoholic Steatohepatitis. J Pharmacol Sci.

2011 Mar 17;115(3):270-3. Epub 2011 Feb 22.

289.Yoneda M, Nakajima A, Wada K. Novel Findings for the Development of

DrugTherapy for Various Liver Diseases:Preface. J Pharmacol Sci. 2011 Mar

17;115(3):259-62. Epub 2011 Feb 22.

290.Fujita K, Wada K, Nozaki Y, Yoneda M, Endo H, Takahashi H, Kirikoshi H, Inamori

M, Saito S, Nakajima A. Serum nitric oxide metabolite as a biomarker of visceral fat

accumulation: Clinical significance of measurement for nitrate/nitrite. Med Sci

Monit. 2011 Feb 25;17(3):CR123-131.

291.Sakamoto Y, Kato S, Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo H,

Fujita K, Koide T, Takahashi H, Yoneda M, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kubota K, Maeda S, Nakajima A, Inamori M (Corresponding author). Change of

gastric emptying with chewing gum: evaluation using a continuous real-time 13C

breath test (BreathID system). Journal of Neurogastroentrology and Motility 2011

Apr;17(2):174-9. doi: 10.5056/jnm.2011.17.2.174. Epub 2011 Apr 27.

292.Kusayama M, Wada K, Nagata M, Ishimoto S, Takahashi H, Yoneda M, Nakajima A,

Okura M, Kogo M, Kamisaki Y. Critical role of aquaporin 3 on growth of human

esophageal and oral squamous cell carcinoma. Cancer Sci. 2011 Jun;102(6):1128-36.

doi: 10.1111/j.1349-7006.2011.01927.x. Epub 2011 Apr 24.

293.Endo H, Hosono K, Uchiyama T, Sakai E, Sugiyama M, Takahashi H, Nakajima N,

Wada K, Takeda K, Nakagama H, Nakajima A. Leptin acts as a growth factor for

colorectal tumours at stages subsequent to tumour initiation in murine colon

carcinogenesis. Gut. 2011 Oct;60(10):1363-71. Epub 2011 Mar 15.

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294.Okada K, Fujisaki J, Kasuga A, Omae M, Hirasawa T, Ishiyama A, Inamori M,

Chino A, Yamamoto Y, Tsuchida T, Nakajima A, Hoshino E, Igarashi M. Diagnosis of

undifferentiated type early gastric cancers by magnification endoscopy with

narrow-band imaging. J Gastroenterol Hepatol. 2011 Aug;26(8):1262-9. doi:

10.1111/j.1440-1746.2011.06730.x.

295.Kubota K, Watanabe S, Uchiyama T, Kato S, Sekino Y, Suzuki K, Mawatari H, Iida

H, Endo H, Fujita K, Yoneda M, Takahashi H, Kirikoshi H, Kobayashi N, Saito S,

Sugimori K, Hisatomi K, Matsuhashi N, Sato H, Tanida E, Sakaguchi T, Fujisawa N,

Nakajima A. Factors predictive of relapse and spontaneous remission of

autoimmune pancreatitis patients treated/not treated with corticosteroids J

Gastroenterol. 2011 Jun;46(6):834-42. Epub 2011 Apr 15.

296.Hosono K, Endo H, Sakai E, Sekino Y, Uchiyama T, Watanabe S, Iida H, Sakamoto

Y, Koide T, Takahashi H, Yoneda M, Tokoro C, Abe Y, Inamori M, Kobayashi N,

Kubota K, Nakajima A. Optimal Approach for Small Bowel Capsule Endoscopy

Using Polyethylene Glycol and Metoclopramide with the Assistance of a Real-Time

Viewer. Digestion. 2011 Apr 15;84(2):119-125. [Epub ahead of print]

297.Nonaka T, Kessoku T, Ogawa Y, Imajyo K, Yanagisawa S, Shiba T, Sakaguchi T,

Atsukawa K, Takahashi H, Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K,

Endo H, Sakamoto Y, Fujita K, Yoneda M, Koide T, Takahashi H, Tokoro C, Abe Y,

Maeda S, Nakajima A, Inamori M. Effects of histamine H2 receptor antagonists and

proton pump inhibitors on the rate of gastric emptying: a crossover study using a

continuous real-time 13C breath test (BreathID system). Journal of

Neurogastroentrology and Motility. 2011 Jul; 17(3): 287-293

298.Endo H, Higurashi T, Hosono K, Sakai E, Sekino Y, Iida H, Sakamoto Y, Koide

T,Takahashi H, Yoneda M, Tokoro C, Inamori M, Abe Y, Nakajima A. Efficacy

ofLactobacillus casei treatment on small bowel injury in chronic low-dose

aspirinusers: a pilot randomized controlled study. J Gastroenterol. 2011

Jul;46(7):894-905. Epub 2011 May 10.

299.Tokoro C, Inamori M, Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo H,

Sakamoto Y, Takahashi H, Koide T, Yasizaki H, Goto A, Abe Y, Kawana I, Nakajima

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A, Maeda S, Ohshiro H, Inayama Y. Localized primary AL amyloidosis of the colon

without other gastrointestinal involvement. Gastrointestinal Endoscopy. 2011

Oct;74(4):925-927. Epub 2011 Aug 6. No abstract available.

300.Uchiyama T, Takahashi H, Endo H, Sugiyama M, Sakai E, Hosono K, Nagashima Y,

Inayama Y, Wada K, Hippo Y, Nakajima A. Role of the long form leptin receptor and

of the STAT3 signaling pathway in colorectal cancer progression. Int J Oncol. 2011

Oct;39(4):935-40. doi: 10.3892/ijo.2011.1105. Epub 2011 Jun 29.

301.Iida H, Endo H, Sekino Y, Sakai E, Uchiyama T, Hosono K, Nonaka T, Sakamoto Y,

Fujita K, Yoneda M, Koide T, Takahashi H, Tokoro C, Goto A, Abe Y, Gotoh E, Maeda

S, Nakajima A, Inamori M (Corresponding author). A new noninvasive modality for

recording sequential images and the pH of the small bowel. Hepatogastroenterology

2011 Aug 10;59(114)

302.Sekino Y, Imajo K, Sakai E, Uchiyama T, Iida H, Endo H, Hosono K, Sakamoto Y,

Fujita K, Yoneda M, Takahashi H, Koide T, Tokoro C, Abe Y, Saito S, Maeda S, Gotoh

E, Takihata M, Terauchi Y, Nakajima A, Inamori M. Time-course of changes of

visceral fat area, liver volume and liver fat area during intragastric balloon therapy

in Japanese super-obese patients. Intern Med. 2011;50(21):2449-55. Epub 2011 Nov

1.

303.Sakai E, Takahashi H, Kato S, Uchiyama T, Hosono K, Endo H, Maeda S, Yoneda M,

Taguri M, Nakajima A. Investigation of the prevalence and number of aberrant

crypt foci associated with human colorectal neoplasm. Cancer Epidemiol

Biomarkers Prev. 2011 Sep;20(9):1918-24. Epub 2011 Jul 12.

304.Nonaka T, Inamori M, Kessoku T, Ogawa Y, Yanagisawa S, Shiba T, Sakaguchi T,

Gotoh E, Maeda S, Gotoh E, Nakajima A, Atsukawa K, Takahashi H, Akasaka Y. A

case of rectal cancer arising from long-standing prolapsed mucosa of the rectum.

Intern Med 2011;50(21):2569-73. Epub 2011 Nov 1.

305.Hotta K, Kitamoto T, Kitamoto A, Mizusawa S, Matsuo T, Nakata Y, Kamohara S,

Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A,

Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Hamaguchi K, Tanaka

K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Nakao

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K, Sekine A. Association of variations in the FTO, SCG3 and MTMR9 genes with

metabolic syndrome in a Japanese population. J Hum Genet. Sep;56(9):647-51. doi:

10.1038/jhg.2011.74. Epub 2011 Jul 28.

306.Hotta K, Kitamoto T, Kitamoto A, Mizusawa S, Matsuo T, Nakata Y, Hyogo H, Ochi

H, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J,

Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T,

Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H,

Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A. Computed tomography

analysis of the association between the SH2B1 rs7498665 single-nucleotide

polymorphism and visceral fat area. J Hum Genet. 2011 Oct;56(10):716-9. doi:

10.1038/jhg.2011.86. Epub 2011 Jul 28.

307.Iida H, Kato S, Sekino Y, Sakai E, Uchiyama T, Endo H, Hosono K, Sakamoto Y,

Fujita K, Yoneda M, Koide T, Takahashi H, Tokoro C, Goto A, Abe Y, Kobayashi N,

Kubota K, Gotoh E, Maeda S, Nakajima A, Inamori M. Early effects of oral

administration of omeprazole and roxatidine on the intragastric pH. JZUSB 2012

Jan;13(1):29-34.

308.Aikou S, Ohmoto Y, Gunji T, Matsuhashi N, Ohtsu H, Miura H, Kubota K,

Yamagata Y, Seto Y, Nakajima A, Goldenring JR, Kaminishi M, Nomura S. Tests for

Serum Levels of Trefoil Factor Family Proteins Can Improve Gastric Cancer

Screening. Gastroenterology. 2011 Sep;141(3):837-845.e1-7. Epub 2011 May 27.

309.Sakamoto Y, Sekino Y, Yamada E, Ohkubo H, Higurashi T, Sakai E, Iida H, Hosono

K, Endo H, Nonaka T, Ikeda T, Fujita K, Yoneda M, Koide T, Takahashi H, Goto A,

Abe Y, Gotoh E, Maeda S, Nakajima A, Inamori M. Mosapride accelerates the

delayed gastric emptying of high-viscosity liquids: a crossover study using

continuous real-time 13C breath test (BreathID system). J Neurogastroenterol

Motil.in press. 2011 Oct; 17(4): 395-401

310.Yoneda M, Imajo K, Kirikoshi H, Nakajima A. Acoustic radiation force-based shear

stiffness and non-invasive panels of tests in Japanese patients with nonalcoholic

fatty liver disease. J Hepatol. 2011 Aug 29. [Epub ahead of print]

311.Nakano K, Hokamura K, Taniguchi N, Wada K, Kudo C, Nomura R, Kojima A,

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Naka S, Muranaka Y, Thura M, Nakajima A, Masuda K, Nakagawa I, Speziale P,

Shimada N, Amano A, Kamisaki Y, Tanaka T, Umemura K, Ooshima T. The

collagen-binding protein of Streptococcus mutans is involved in haemorrhagic

stroke. Nat Commun. 2011 Sep 27;2:485. doi: 10.1038/ncomms1491.

312.Higurashi T, Endo H, Yoneda M, Hosono K, Sakai E, Takahashi H, Inamori M,

Uchiyama S, Kojima T, Kawana K, Natsumeda Y, Nagase H, Nakajima A.

Capsule-Endoscopic Findings of Ulcerative Colitis Patients. Digestion. 2011 Oct

28;84(4):306-314. [Epub ahead of print]

313.Hotta K, Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, Matsuo T, Nakata Y,

Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Komatsu R,

Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S,

Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa

T, Oikawa S, Yoshimatsu H, Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A.

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a

reduction in visceral and subcutaneous fat areas in Japanese women. J Hum Genet.

2011 Nov 10. doi: 10.1038/jhg.2011.127. [Epub ahead of print]

314.Sakai E, Morioka T, Yamada E, Ohkubo H, Higurashi T, Hosono K, Endo H,

Takahashi H, Takamatsu R, Cui C, Shiozawa M, Akaike M, Samura H, Nishimaki T,

Nakajima A, Yoshimi N. Identification of preneoplastic lesions as mucin-depleted

foci in patients with sporadic colorectal cancer. Cancer Sci. 2011 Oct 20. doi:

10.1111/j.1349-7006.2011.02125.x. [Epub ahead of print]

315.Iwasaki T, Yoneda M, Inamori M, Shirakawa J, Higurashi T, Maeda S, Terauchi Y,

Nakajima A. Sitagliptin as a Novel Treatment Agent for Non-Alcoholic Fatty Liver

Disease Patients with Type 2 Diabetes Mellitus. Hepatogastroenterology. 2011 Oct

12;58(112).2103-5. doi: 10.5754/hge11263. [Epub ahead of print]

316.Yamada E, Endo H, Nakajima A, Yamanaka S. Disseminated Mycobacterium avium

disease with nodular infiltration in the small intestine, detected by capsule

endoscopy. Endoscopy. 2011 Oct;43 Suppl 2:E332-3. Epub 2011 Oct 21. No abstract

available.

317.Chiba H, Sekiguchi M, Ito T, Tsuji Y, Ohata K, Ohno A, Umezawa S, Takeuchi

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S,Hisatomi K, Teratani T, Matsuhashi N, Endo H, Inamori M, Nakajima A. Is It

Worthwhile to Perform Capsule Endoscopy for Asymptomatic Patients with Positive

Immunochemical Faecal Occult Blood Test? Dig Dis Sci.2011 Dec;56(12):3459-62.

Epub 2011 Jun 25.

318.Kato S, Kubota K, Shimamura T, Shinohara Y, Kobayashi N, Watanabe S, Yoneda

M, Inamori M, Nakamura F, Ishiguro H, Nakaigawa N, Nagashima Y, Taguri M,

KubotaY, Goshima Y, Morita S, Endo I, Maeda S, Nakajima A, Nakagama H.

Semaphorin 4D, a lymphocyte semaphorin, enhances tumor cell motility through

binding its receptor, plexinB1, in pancreatic cancer. Cancer Sci. 2011

Nov;102(11):2029-2037. doi: 10.1111/j.1349-7006.2011.02053.x. Epub 2011 Sep 13.

319.Ishimoto S, Wada K, Tanaka N, Yamanishi T, Ishihama K, Aikawa T, Okura M,

Nakajima A, Kogo M, Kamisaki Y. Role of endothelin receptor signalling in

squamous cell carcinoma. Int J Oncol. 2012 Apr;40(4):1011-9. doi:

10.3892/ijo.2011.1258. Epub 2011 Nov 10.

320.Iida H, Inamori M, Sekino Y, Sakamoto Y, Yamato S, Nakajima A, A review of the

reported cases of chronic intestinal pseudo-obstruction in Japan and an investigation

of proposed new diagnostic criteria Clin J Gastroenterol (2011) 4:141-146

321.Sakamoto Y, Sekino Y, Yamada E, Higurashi T, Ohkubo H, Sakai E, Endo H, Iida H,

Nonaka T, Fujita K, Yoneda M, Koide T, Takahashi H, Goto A, Abe Y, Gotoh E,

Maeda S, Nakajima A, Inamori M. Effect of sumatriptan on gastric emptying: a

crossover study using BreathID system. World J Gastroenterol. 2012 Jul

14;18(26):3415-9.

322.Iwasaki T, Tomeno W, Yoneda M, Inamori M, Shirakawa J, Imajo K, Kawashima K,

Terauchi Y, Nakajima A. Non-Alcoholic Fatty Liver Disease Adversely Affects the

Glycemic Control Afforded by Sitagliptin. Hepatogastroenterology. 2011 Dec

6;59(117). doi: 10.5754/hge11689.

323.Suzuki K, Uchiyama S, Imajyo K, Tomeno W, Sakai E, Yamada E, Tanida E,

Akiyama T, Watanabe S, Endo H, Fujita K, Yoneda M, Takahashi H, Koide T, Tokoro

C, Abe Y, Kawaguchi M, Gotoh E, Maeda S, Nakajima A, Inamori M. Risk factors for

colonic diverticular hemorrhage: Japanese multicenter study. Digestion. 2012 in

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press. 2012 Jun;85(4):261-5. Epub 2012 Mar 30.

324.Masaki T, Sugihara K, Nakajima A, Muto T. Nationwide survey on adult type

chronic intestinal pseudo-obstruction in surgical institutions in Japan. Surg Today.

2012 Feb;42(3):264-71. Epub 2012 Jan 12.

325.Homma Y, Akiyama H, Matsuyama R, Makino H, Sakamoto Y, Inamori M,

Nakajima A, Maeda S, Tanaka K, Kunisaki C, Endo I. Assessment of Gastric

Emptying Function after Gastrectomy using a Real-Time 13C Breath Test.

Hepatogastroenterology. 2012 Jan 13;59(119). doi: 10.5754/hge11849. [Epub ahead of

print]

326.Ohkubo H, Takahashi H, Yamada E, Sakai E, Higurashi T, Uchiyama T, Hosono K,

Endo H, Taguri M, Nakajima A. Natural history of human aberrant crypt foci and

correlation with risk factors for colorectal cancer. Oncol Rep. 2012 May;27(5):1475-80.

doi: 10.3892/or.2012.1631. Epub 2012 Jan 12.

327.Okada K, Fujisaki J, Yoshida T, Ishikawa H, Suganuma T, Kasuga A, Omae M,

Kubota M, Ishiyama A, Hirasawa T, Chino A, Inamori M, Yamamoto Y, Yamamoto N,

Tsuchida T, Tamegai Y, Nakajima A, Hoshino E, Igarashi M. Long-term outcomes of

endoscopic submucosal dissection for undifferentiated-type early gastric cancer.

Endoscopy. 2012 Feb;44(2):122-7. Epub 2012 Jan 23.

328.Yoneda M, Naka S, Nakano K, Wada K, Endo H, Mawatari H, Imajo K, Nomura R,

Hokamura K, Ono M, Murata S, Tohnai I, Sumida Y, Shima T, Kuboniwa M,

Umemura K, Kamisaki Y, Amano A, Okanoue T, Ooshima T, Nakajima A.

Involvement of a periodontal pathogen, Porphyromonas gingivalis on the

pathogenesis of non-alcoholic fatty liver disease. BMC Gastroenterol. 2012 Feb

16;12(1):16. [Epub ahead of print]

329.Akiyama T, Chiba K, Jono F, Akimoto K, Takahata A, Fujisawa N, Inamori M,

Maeda S, Nakajima A, Nakamura A, Koyama S. Successful endoscopic removal of a

press-through package in the terminal ileum causing obstructive ileus. Gastrointest

Endosc. 2012 Mar;75(3):671-2. No abstract available.

330.Hotta K, Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, So R, Matsuo T,

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Nakata Y, Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K,

Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki

S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K,

Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Tanaka K, Matsuzawa Y, Nakao K,

Sekine A. Association between type 2 diabetes genetic susceptibility loci and visceral

and subcutaneous fat area as determined by computed tomography. J Hum Genet.

2012 May;57(5):305-10. doi: 10.1038/jhg.2012.21. Epub 2012 Mar 1.

331.Mawatari H, Yoneda M, Kirikoshi H, Maeda S, Nakajima A, Saito S.

Thrombocytopenia is more severe in patients with chronic hepatitis C than in

patients with nonalcoholic fatty liver disease. J Gastroenterol. 2012 May;47(5):606-7.

Epub 2012 Mar 3.

332.Iida H, Inamori M, Fujii T, Sekino Y, Endo H, Hosono K, Nonaka T, Koide T,

Takahashi H, Yoneda M, Goto A, Abe Y, Kobayashi N, Kirikoshi H, Kubota K, Saito

S, Gotoh E, Maeda S, Nakajima A. Early effect of oral administration of omeprazole

with mosapride as compared with those of omeprazole alone on the intragastric pH.

BMC Gastroenterol. 2012 Mar 26;12(1):25. [Epub ahead of print]

333.Higurashi T, Takahashi H, Endo H, Hosono K, Yamada E, Ohkubo H, Sakai E,

Uchiyama T, Hata Y, Fujisawa N, Uchiyama S, Ezuka A, Nagase H, Kessoku T,

Matsuhashi N, Nakayama S, Inayama Y, Morita S, Nakajima A. Metformin efficacy

and safety for colorectal polyps: a double-blind randomized controlled trial. BMC

Cancer. 2012 Mar 26;12(1):118. [Epub ahead of print]

334.Kojima A, Nakano K, Wada K, Takahashi H, Katayama K, Yoneda M, Higurashi T,

Nomura R, Hokamura K, Muranaka Y, Matsuhashi N, Umemura K, Kamisaki Y,

Nakajima A, Ooshima T. Infection of specific strains of Streptococcus mutans, oral

bacteria, confers a risk of ulcerative colitis. Sci Rep. 2012;2:332. Epub 2012 Mar 26.

335.Kobayashi N, Sugimori K, Shimamura T, Hosono K, Watanabe S, Kato S, Ueda M,

Endo I, Inayama Y, Maeda S, Nakajima A, Kubota K. Endoscopic ultrasonographic

findings predict the risk of carcinoma in branch duct intraductal papillary mucinous

neoplasms of the pancreas. Pancreatology. 2012 Mar;12(2):141-5. Epub 2012 Jan 14.

336.Kirikoshi H, Yoneda M, Mawatari H, Fujita K, Imajo K, Kato S, Suzuki K,

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Kobayashi N, Kubota K, Maeda S, Nakajima A, Saito S. Is hepatic arterial infusion

chemotherapy effective treatment for advanced hepatocellular carcinoma resistant to

transarterial chemoembolization? World J Gastroenterol. 2012 Apr 28;18(16):1933-9.

337.Ishimoto S, Wada K, Usami Y, Tanaka N, Aikawa T, Okura M, Nakajima A, Kogo M,

Kamisaki Y. Differential expression of aquaporin 5 and aquaporin 3 in squamous cell

carcinoma and adenoid cystic carcinoma. Int J Oncol. 2012 Jul;41(1):67-75. doi:

10.3892/ijo.2012.1445. Epub 2012 Apr 20.

338.Akiyama T, Sekino Y, Iida H, Koyama S, Gotoh E, Maeda S, Nakajima A, Inamori M.

Endoscopic diagnosis of Barrett’s esophagus. World J Gastroenterol. 2012 Jul

14;18(26):3477-8.

339.Sekino Y, Endo H, Yamada E, Sakai E, Ohkubo H, Higurashi T, Iida H, Hosono K,

Takahashi H, Koide T, Nonaka T, Abe Y, Gotoh E, Maeda S, Nakajima A, Inamori M

(Corresponding author). Clinical associations and risk factors for bleeding from

colonic angiectasia: a case-controlled study. Colorectal Disease. 2012

Oct;14(10):e740-6.

340.Imajo K, Fujita K, Nozaki Y, Kato S, Yoneda M, Kirikoshi H, Ikejima K, Watanabe S,

Wada K, Nakajima A. Hyperresponsivity to low-dose endotoxin during

progressionto nonalcoholic steatohepatitis is regulated by leptin-mediated signaling.

Cell Metab. 2012 Jul 3;16(1):44-54. doi: 10.1016/j.cmet.2012.05.012.

341.Sekino Y, Yamada E, Sakai E, Ohkubo H, Higurashi T, Iida H, Endo H, Takahashi

H, Koide T, Sakamoto Y, Nonaka T, Gotoh E, Maeda S, Nakajima A, Inamori M.

Influence of sumatriptan on gastric accommodation and on antral contraction in

healthy subjects assessed by ultrasonography. Neurogastroenterology and Motility.

2012 Dec;24(12):1083-e564.

342.Nakajima T, Matsuhashi N, Nara S, Nakajima A, Imura J, Kihara A, Murata K,

Fukushima J, Horiuchi H. An adult case of midgut volvulus in familial

visceralmyopathy. Pathol Int. 2012 Aug;62(8):554-8. Epub 2012 Jun 25. PubMed

PMID: 22827765.

343.Sakamoto Y, Sekino Y, Yamada E, Higurashi T, Ohkubo H, Sakai E, Endo H, Iida H,

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Nonaka T, Fujita K, Yoneda M, Koide T, Takahashi H, Goto A, Abe Y, Gotoh E,

Maeda S, Nakajima A, Inamori M. Effect of sumatriptan on gastric emptying: A

crossover study using the BreathID system. World J Gastroenterol. 2012 Jul

14;18(26):3415-9. PubMed PMID: 22807611; PubMed Central PMCID:

PMC3396194.

344.Imajo K, Fujita K, Yoneda M, Shinohara Y, Suzuki K, Mawatari H, Takahashi J,

Nozaki Y, Sumida Y, Kirikoshi H, Saito S, Nakamuta M, Matsuhashi N, Wada K,

Nakajima A. Plasma free choline is a novel non-invasive biomarker for early-stage

non-alcoholic steatohepatitis: A multi-center validation study. Hepatol Res. 2012

Aug;42(8):757-66. doi: 10.1111/j.1872-034X.2012.00976.x. Epub 2012 Mar 12.

PubMed

345.Sato T, Kato S, Watanabe S, Hosono K, Kobayashi N, Nakajima A, Kubota K.

Primary leiomyoma of the pancreas diagnosed by endoscopic ultrasound-guided

fine-needle aspiration. Dig Endosc. 2012 Sep;24(5):380.

346.Uchiyama T, Takahashi H, Endo H, Kato S, Sakai E, Hosono K, Yoneda M, Inamori

M, Hippo Y, Nakagama H, Nakajima A. Number of aberrant crypt foci in the rectum

is a useful surrogate marker of colorectal adenoma recurrence. Dig Endosc. 2012

Sep;24(5):353-7. doi: 10.1111/j.1443-1661.2012.01289.x. Epub 2012 Apr 2. PubMed

347.Nakamura A, Tajima K, Zolzaya K, Sato K, Inoue R, Yoneda M, Fujita K, Nozaki Y,

Kubota KC, Haga H, Kubota N, Nagashima Y, Nakajima A, Maeda S, Kadowaki T,

Terauchi Y. Protection from non-alcoholic steatohepatitis and liver tumourigenesis

in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance.

Diabetologia. 2012 Dec;55(12):3382-91. doi: 10.1007/s00125-012-2703-1. Epub 2012

Sep 7.

348.Sekino Y, Inamori M, Yamada E, Ohkubo H, Sakai E, Higurashi T, Iida H, Hosono K,

Endo H, Nonaka T, Takahashi H, Koide T, Abe Y, Gotoh E, Koyano S, Kuroiwa Y,

Maeda S, Nakajima A. Characteristics of intestinal pseudo-obstruction in patients

with mitochondrial diseases. World J Gastroenterol. 2012 Sep 7;18(33):4557-62.

349.Higurashi T, Hosono K, Endo H, Takahashi H, Iida H, Uchiyama T, Ezuka A,

Uchiyama S, Yamada E, Ohkubo H, Sakai E, Maeda S, Morita S, Natsumeda Y,

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Nagase H, Nakajima A. Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant

crypt foci (ACF): a double-blind randomized controlled trial. BMC Cancer. 2012 Sep

19;12(1):413. [Epub ahead of print] PMID: 22992267

350.Kubota K, Sato T, Kato S, Watanabe S, Hosono K, Kobayashi N, Hisatomi K,

Matsuhashi N, Nakajima A. Needle-knife precut papillotomy with a small incision

over a pancreatic stent improves the success rate and reduces the complication rate

in difficult biliary cannulations. J Hepatobiliary Pancreat Sci. 2013

Mar;20(3):382-8.

351.Nonaka T, Kessoku T, Ogawa Y, Yanagisawa S, Shiba T, Sakaguchi T, Atsukawa K,

Takahashi H, Sekino Y, Iida H, Endo H, Sakamoto Y, Koide T, Takahashi H, Yoneda

M, Maeda S, Nakajima A, Gotoh E, Inamori M (Corresponding author).

Comparative Study of 2 Different Questionnaires in Japanese Patients: The Quality

of Life and Utility Evaluation Survey Technology Questionnaire (QUEST) Versus

the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease

Questionnaire (FSSG). J Neurogastroenterol Motil. 2013 Jan;19(1):54-60. doi:

10.5056/jnm.2013.19.1.54. Epub 2013 Jan 8.

352.Endo H, Sakai E, Higurashi T, Yamada E, Ohkubo H, Iida H, Koide T, Yoneda

M,Abe Y, Inamori M, Hosono K, Takahashi H, Kubota K, Nakajima A. Differences in

the severity of small bowel mucosal injury based on the type of aspirin as evaluated

by capsule endoscopy. Dig Liver Dis. 2012 Oct;44(10):833-8.

353.Kadomatsu Y, Kojima T, Kohara M, Inamori M. Hepatic Portal Venous Gas

Following Percutaneous Endoscopic Gastrostomy. Internal Medicine. 2013;52(1):153.

Epub 2013 Jan 1.

354.Hirata K, Katayama K, Nakajima A, Takada K, Kamisaki Y, Wada K. Role of

leukotriene B(4) receptor signaling in human preadipocyte differentiation. Biochem

Biophys Res Commun. 2012 Nov 5. doi:pii: S0006-291X(12)02102-X.

10.1016/j.bbrc.2012.10.110. [Epub ahead of print] PubMed PMID: 23137534.

355.Hosono K, Yamada E, Endo H, Takahashi H, Inamori M, Hippo Y, Nakagama H,

Nakajima A. Increased tumor necrosis factor receptor 1 expression in human

colorectal adenomas. World J Gastroenterol. 2012 Oct 14;18(38):5360-8. doi:

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10.3748/wjg.v18.i38.5360.

356.Yoneda M, Imajo K, Eguchi Y, Fujii H, Sumida Y, Hyogo H, Ono M, Suzuki

Y,Kawaguchi T, Aoki N, Sata M, Kanemasa K, Kohgo Y, Saibara T, Chayama K, Itoh

Y,Yoshikawa T, Anzai K, Fujimoto K, Okanoue T, Nakajima A; Japan Study Group of

Nonalcoholic Fatty Liver Disease (JSG-NAFLD). Noninvasive scoring systems in

patients with nonalcoholic fatty liver disease with normal alanine aminotransferase

levels. J Gastroenterol. 2013 Sep;48(9):1051-60. doi: 10.1007/s00535-012-0704-y.

Epub 2012 Nov 27.

357.Yagi K, Takahashi H, Akagi K, Matsusaka K, Seto Y, Aburatani H, Nakajima A,

Kaneda A. Intermediate methylation epigenotype and its correlation to KRAS

mutation in conventional colorectal adenoma. Am J Pathol. 2012 Feb;180(2):616-25.

Epub 2011 Nov 21. PubMed PMID: 22115708.

358.Tomeno W, Yoneda M, Imajo K, Suzuki K, Ogawa Y, Shinohara Y, Mawatari

H,Fujita K, Shibata W, Kirikoshi H, Maeda S, Nakajima A, Saito S. Evaluation of

the Liver Fibrosis Index calculated by using real-time tissue elastography for the

non-invasive assessment of liver fibrosis in chronic liver diseases. Hepatol Res. 2013

Jul;43(7):735-42. doi: 10.1111/hepr.12023. Epub 2012 Dec 6.

359.Hotta K, Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, So R, Matsuo T,

Nakata Y, Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Itoh

N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K,

Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S,

Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A. Replication Study of 15

Recently Published Loci for Body Fat Distribution in the Japanese Population. J

Atheroscler Thromb. 2013 Apr 25;20(4):336-50. Epub 2012 Dec 7.

360.Oshima A, Hosono K, Ito S, Sekino Y, Iida H, Nonaka T, Yamanaka S, Nakajima A,

Maeda S, Gotoh E, Inamori M. Ischemic gastritis. Turk J Gastroenterol. 2014

Dec;25 Suppl 1:289-90. doi: 10.5152/tjg.2014.4114.

361.Ida T, Morohashi T, Ohara H, Goto T, Inamori M, Nakajima A, Maeda S, Tsukumo Y,

Sakamoto A, Ishikawa Y. Gastric neuroendocrine carcinoma with non-islet cell

tumor hypoglycemia associated with enhanced production of insulin-like growth

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factor II: a case report. Internal Medicine. 2013;52(7):757-60. Epub 2013 Apr 1.

362.Takahashi H, Yamada E, Ohkubo H, Sakai E, Higurashi T, Uchiyama T, Hosono

K,Endo H, Nakajima A. Relationship of human rectal aberrant crypt foci and

formation of colorectal polyp: One-year following up after polypectomy. World J

Gastrointest Endosc. 2012 Dec 16;4(12):561-4.

363.Suzuki K, Yoneda M, Imajo K, Kirikoshi H, Nakajima A, Maeda S, Saito S.

Transient elastography for monitoring the fibrosis of non-alcoholic fatty liver

disease for 4 years. Hepatol Res. 2013 Sep;43(9):979-83. doi: 10.1111/hepr.12039.

Epub 2013 Jan 7.

364.Sogawa K, Noda K, Umemura H, Seimiya M, Kuga T, Tomonaga T, Nishimura M,

Kanai F, Imazeki F, Takizawa H, Yoneda M, Nakajima A, Tsutsumi M, Yokosuka O,

Nomura F. Serum fibrinogen alpha C-chain 5.9 kDa fragment (FIC 5.9) as a

biomarker for early detection of hepatic fibrosis related to hepatitis C virus.

Proteomics Clin Appl. 2013 Jun;7(5-6):424-31. doi: 10.1002/prca.201200094. Epub

2013 May 17.

365.Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Kirikoshi H, Funakoshi K,

Ikeda M, Kato N, Nakajima A, Saito S. Unfolded Protein Response pathways

regulate Hepatitis C Virus replication via modulation of Autophagy. Biochem

Biophys Res Commun. 2013 Mar 8;432(2):326-32. doi: 10.1016/j.bbrc.2013.01.103.

Epub 2013 Feb 6.

366.Kubota K, Fujita Y, Sato T, Watanabe S, Hosono K, Yoneda M, Kirikoshi H,

Hisatomi K, Matsuhashi N, Endo I, Inayama Y, Nakajima A. Tumor diameter and

Ki-67 expression in biopsy could be diagnostic markers discriminating from

adenoma and early stage cancer in patients with ampullary tumors. J Hepatobiliary

Pancreat Sci. 2013 Jun;20(5):531-7. doi: 10.1007/s00534-013-0594-2.

367.Takashi Uchiyama, Hirokazu Takahashi, Hiroki Endo, Eiji Sakai, Kunihiro Hosono,

Yoji Nagashima, Atsushi Nakajima IL-6 Plays Crucial Roles in Sporadic Colorectal

Cancer through the Cytokine Networks including CXCL7 PP. Journal of Cancer

Therapy Vol.3,No 6A 874-879, Pub. November 28, 2012

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368.Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Nakamura T, Teranishi H,

Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A, Hotta K.

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and

PARVB genes are associated with development and progression of nonalcoholic fatty

liver disease in Japan. Hum Genet. 2013 Jul;132(7):783-92. doi:

10.1007/s00439-013-1294-3. Epub 2013 Mar 28.

369.Sakai E, Endo H, Kato S, Matsuura T, Tomeno W, Taniguchi L, Uchiyama T, Hata Y,

Yamada E, Ohkubo H, Higrashi T, Hosono K, Takahashi H, Nakajima A. Capsule

endoscopy with flexible spectral imaging color enhancement reduces the bile

pigment effect and improves the detectability of small bowel lesions. BMC

Gastroenterol. 2012;12:83.

370.Imajo K, Yoneda M, Fujita K, Kessoku T, Tomeno W, Ogawa Y, Shinohara Y, Sekino

Y, Mawatari H, Nozaki Y, Kirikoshi H, Taguri M, Toshima G, Takahashi J, Saito S,

Wada K, Nakajima A. Oral choline tolerance test as a novel noninvasive method for

predicting nonalcoholic steatohepatitis. J Gastroenterol. 2014 Feb;49(2):295-304.

doi: 10.1007/s00535-013-0776-3. Epub 2013 Mar 16.

371.Ohkubo H, Kessoku T, Fuyuki A, Iida H, Inamori M, Fujii T, Kawamura H, Hata Y,

Manabe N, Chiba T, Kwee TC, Haruma K, Matsuhashi N, Nakajima A, Takahara T.

Assessment of Small Bowel Motility in Patients With Chronic Intestinal

Pseudo-Obstruction Using Cine-MRI. Am J Gastroenterol. 2013 Jul;108(7):1130-9.

doi: 10.1038/ajg.2013.57. Epub 2013 Mar 19.

372.Kubota K, Sato T, Watanabe S, Hosono K, Kobayashi N, Mori R, Taniguchi K,

Matsuyama R, Endo I, Nakajima A. Covered self-expandable metal stent

deployment promises safe neoadjuvant chemoradiation therapy in patients with

borderline resectable pancreatic head cancer. Dig Endosc. 2014 Jan;26(1):77-86. doi:

10.1111/den.12049. Epub 2013 Mar 31.

373.Watanabe S, Kobayashi N, Kubota K, Sato T, Kato S, Hosono K, Shimamura T,

Inayama Y, Nakajima A, Endo I. A novel scoring system for arterial invasion of

pancreatic body and tail cancer based on multidetector row computed tomography

and biomarkers. Pancreatology. 2013 Mar-Apr;13(2):161-9. doi:

10.1016/j.pan.2012.12.364. Epub 2013 Jan 22.

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374.Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Fujita K, Kirikoshi H,

Takahashi J, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S. Hepatic

triglyceride lipase plays an essential role in changing the lipid metabolism in

genotype 1b hepatitis C virus replicon cells and hepatitis C patients. Hepatol Res.

2013 Nov;43(11):1190-8. doi: 10.1111/hepr.12072. Epub 2013 May 10.

375.Nonaka T, Sekino Y, Iida H, Yamada E, Ohkubo H, Sakai E, Higurashi T, Hosono K,

Endo H, Koide T, Takahashi H, Fujita K, Yoneda M, Goto A, Kusakabe A, Kobayashi

N, Gotoh E, Maeda S, Nakajima A, Nosaka C, Inamori M. Early Effect of

Single-dose Sitagliptin Administration on Gastric Emptying: Crossover Study Using

the (13)C Breath Test. J Neurogastroenterol Motil. 2013 Apr;19(2):227-32. doi:

10.5056/jnm.2013.19.2.227. Epub 2013 Apr 16.

376.Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, So R, Matsuo T, Nakata Y,

Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Komatsu R,

Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S,

Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa

T, Oikawa S, Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A, Hotta K.

NUDT3 rs206936 is associated with body mass index in obese Japanese women.

Endocr J. 2013 Aug 31;60(8):991-1000. Epub 2013 May 25.

377.Kurita Y, Koide T, Watanabe S, Ogawa T, Sekino Y, Iida H, Nonaka T, Kusakabe A,

Gotoh E, Maeda S, Nakajima A, Inamori M. Postpyloric decompression tube

placement through a gastrostomy for malignant bowel obstruction. BMC Res Notes.

2013 Jun 3;6:217. doi: 10.1186/1756-0500-6-217. PubMed PMID: 23731859; PubMed

Central PMCID: PMC3680198.

378.Ogawa Y, Imajo K, Yoneda M, Kessoku T, Tomeno W, Shinohara Y, Kato S,

Mawatari H, Nozaki Y, Fujita K, Kirikoshi H, Maeda S, Saito S, Wada K, Nakajima

A. Soluble CD14 Levels Reflect Liver Inflammation in Patients with Nonalcoholic

Steatohepatitis. PLoS One. 2013 Jun 7;8(6):e65211.

doi:10.1371/journal.pone.0065211. Print 2013. PubMed PMID: 23762319; PubMed

Central PMCID: PMC3676404.

379.Ezuka A, Kawana K, Nagase H, Takahashi H, Nakajima A. Improvement of

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pneumatosis cystoides intestinalis after steroid tapering in a patient with bronchial

asthma: a case report. J Med Case Rep. 2013 Jun 26;7(1):163. [Epub ahead of print]

PubMed PMID: 23803391.

380.Iida H, Ohkubo H, Inamori M, Nakajima A, Sato H. Epidemiology and clinical

experience of chronic intestinal pseudo-obstruction in Japan: a nationwide

epidemiologic survey. J Epidemiol. 2013;23(4):288-94. PubMed PMID: 23831693.

381.Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kubota K, Kobayashi N, Hosono K,

Watanabe S, Sekino Y, Sato T, Sasaki K, Nakaigawa N, Kubota Y, Inayama Y, Endo

I, Ohno S, Maeda S, Nakajima A. aPKCλ/ι is a beneficial prognostic marker for

pancreatic neoplasms. Pancreatology. 2013 Jul-Aug;13(4):360-8. doi:

10.1016/j.pan.2013.05.006. Epub 2013 May 22.

382.Watanabe S, Sato T, Kato S, Hosono K, Kobayashi N, Nakajima A, Kubota K.

Positioning of nasobiliary tube using magnet-loaded catheters. Endoscopy. 2013

Oct;45(10):835-7. doi: 10.1055/s-0033-1344330. Epub 2013 Jul 29.

383.Tomeno W, Yoneda M, Imajo K, Ogawa Y, Kessoku T, Saito S, Eguchi Y, Nakajima A.

Emerging drugs for non-alcoholic steatohepatitis. Expert Opin Emerg Drugs. 2013

Sep;18(3):279-90. doi: 10.1517/14728214.2013.811232. Epub 2013 Jul 13.

384.Hirata K, Wada K, Murata Y, Nakajima A, Yamashiro T, Kamisaki Y. Critical role of

leukotriene B4 receptor signaling in mouse 3T3-L1 preadipocyte differentiation.

Lipids Health Dis. 2013 Aug 9;12(1):122. doi: 10.1186/1476-511X-12-122. PubMed

PMID: 23937951.

385.Taketani H, Sumida Y, Tanaka S, Imajo K, Yoneda M, Hyogo H, Ono M, Fujii H,

Eguchi Y, Kanemasa K, Chayama K, Itoh Y, Yoshikawa T, Saibara T, Fujimoto K,

Nakajima A; Japan Study Group of NAFLD (JSG-NAFLD). The association of

insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic

fatty liver disease. J Gastroenterol. 2014 Jul;49(7):1163-74. doi:

10.1007/s00535-013-0871-5. Epub 2013 Aug 22.

386.Yamada E, Ohkubo H, Higurashi T, Sakai E, Endo H, Takahashi H, Uchida E,

Tanida E, Izumi N, Kanesaki A, Hata Y, Matsuura T, Fujisawa N, Komatsu K,

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Maeda S, Nakajima A. Visceral obesity as a risk factor for left-sided diverticulitis in

Japan: a multicenter retrospective study. Gut Liver. 2013 Sep;7(5):532-8. doi:

10.5009/gnl.2013.7.5.532. Epub 2013 Jun 11.

387.Kawamura H, Sakai E, Endo H, Taniguchi L, Hata Y, Ezuka A, Nagase H, Kessoku

T, Yamada E, Ohkubo H, Higrashi T, Sekino Y, Koide T, Iida H, Nonaka T,

Takahashi H, Inamori M, Maeda S, Nakajima A. Characteristics of the small bowel

lesions detected by capsule endoscopy in patients with chronic kidney disease.

Gastroenterol Res Pract. 2013;2013:814214. doi: 10.1155/2013/814214. Epub 2013

Aug 26.

388.Imajo K, Yoneda M, Ogawa Y, Wada K, Nakajima A. Microbiota and nonalcoholic

steatohepatitis. Semin Immunopathol. 2014 Jan;36(1):115-32. doi:

10.1007/s00281-013-0404-6. Epub 2013 Dec 14.

389.Imajo K, Yoneda M, Kessoku T, Ogawa Y, Maeda S, Sumida Y, Hyogo H, Eguchi Y,

Wada K, Nakajima A. Rodent models of nonalcoholic fatty liver disease/nonalcoholic

steatohepatitis. Int J Mol Sci. 2014 Jan;36(1):115-32. doi:

10.1007/s00281-013-0404-6. Epub 2013 Dec 14.

390.Fujisawa T, Kagawa K, Hisatomi K, Kubota K, Nakajima A, Matsuhashi N.

Endoscopic papillary large-balloon dilation versus endoscopic papillary

regular-balloon dilation for removal of large bile-duct stones. J Hepatobiliary

Pancreat Sci. 2014 Jun;21(6):405-9. doi: 10.1002/jhbp.42. Epub 2013 Oct 14.

391.Takahashi H, Hosono K, Endo H, Nakajima A. Colon epithelial proliferation and

carcinogenesis in diet-induced obesity. J Gastroenterol Hepatol. 2013 Dec;28 Suppl

4:41-7. doi: 10.1111/jgh.12240.

392.Ohkubo H, Masaki T, Matsuhashi N, Kawahara H, Yokoyama T, Nakajima A,

Ohkura Y. Histopathologic findings in patients with idiopathic megacolon: a

comparison between dilated and non-dilated loops. Neurogastroenterol Motil. 2014

Apr;26(4):571-80. doi: 10.1111/nmo.12303. Epub 2014 Jan 6.

393.Sumida Y, Nakajima A, Itoh Y. Limitations of liver biopsy and non-invasive

diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/ nonalcoholic

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steatohepatitis World J Gastroenterol 2014 January 14; 20(2): 475-485

394.Sakai E, Nakajima A, Kaneda A. Accumulation of aberrant DNA methylation

during colorectal cancer development. World J Gastroenterol. 2014 Jan

28;20(4):978-987. Review.

395.Sakai E, Ohata K, Chiba H, Matsuhashi N, Doi N, Fukushima J, Endo H,

Takahashi H, Tsuji S, Yagi K, Matsusaka K, Aburatani H, Nakajima A, Kaneda A.

Methylation epigenotypes and genetic features in colorectal laterally spreading

tumors. Int J Cancer. 2014 Oct 1;135(7):1586-95. doi: 10.1002/ijc.28814. Epub 2014

Mar 10.

396.Kohjima M, Enjoji M, Yada R, Yoshimoto T, Nakamura T, Fukuizumi K, Fukushima

N, Murata Y, Nakashima M, Kato M, Kotoh K, Shirabe K, Maehara Y, Nakajima A,

Nozaki Y, Honda A, Matsuzaki Y, Nakamuta M. Pathophysiological analysis of

primary biliary cirrhosis focusing on choline/phospholipid metabolism. Liver Int.

2015 Mar;35(3):1095-102. doi: 10.1111/liv.12526. Epub 2014 Mar 31.

397.Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Nakao

K, Sekine A, Chayama K, Nakajima A, Hotta K. Targeted next-generation

sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3

and PARVB with the severity of nonalcoholic fatty liver disease. J Hum Genet. 2014

May;59(5):241-6. doi: 10.1038/jhg.2014.17. Epub 2014 Mar 13.

398.Olszak T, Neves J, Dowds M, Baker K, Glickman J, Davidson N, Lin CS, Jobin C,

Brand S, Sotlar K, Wada K, Katayama K, Nakajima A, Mizuguchi H, Kawasaki K,

Nagata K, Kaser A, Zeissig S, Schreiber S, Müller W, Snapper S, Blumberg R,.

Protective mucosal immunity mediated by epithelial CD1d and IL-10. Nature.

2014 May 22;509(7501):497-502. doi: 10.1038/nature13150. Epub 2014 Apr 6.

399.Yoneda M, Thomas E, Sumida Y, Imajo K, Hyogo H, Fujii H, Ono M, Kawaguchi T,

Eguchi Y, Nakajima A. Uric acid levels decrease with fibrosis progression in patients

with nonalcoholic fatty liver disease. Corresponding Author: Dr. Masato Yoneda

Clin Biochem. 2014 Aug;47(12):1138-9. doi: 10.1016/j.clinbiochem.2014.04.026.

Epub 2014 May 4.

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400.Endo H, Sakai E, Taniguchi L, Kessoku T, Komiya Y, Ezuka A, Kawamura H,

Taguri M, Higurashi T, Ohkubo H, Yamada E, Takahashi H, Inamori M, Maeda S,

Sakaguchi T, Hata Y, Nagase H, Nakajima A. Risk factors for small-bowel mucosal

breaks in chronic low-dose aspirin users: data from a prospective multicenter

capsule endoscopy registry. Gastrointest Endosc. 2014 Nov;80(5):826-34. doi:

10.1016/j.gie.2014.03.024. Epub 2014 May 13.

401.Tanaka T, Tahara-Hanaoka S, Nabekura T, Ikeda K, Jiang S, Tsutsumi S, Inagaki T,

Magoori K, Higurashi T, Takahashi H, Tachibana K, Tsurutani Y, Raza S, Anai M,

Minami T, Wada Y, Yokote K, Doi T, Hamakubo T, Auwerx J, Gonzalez FJ, Nakajima

A, Aburatani H, Naito M, Shibuya A, Kodama T, Sakai J. PPARβ/δ activation of

CD300a controls intestinal immunity. Sci Rep. 2014 Jun 24;4:5412.

doi:10.1038/srep05412. PubMed PMID: 24958459.

402.Higurashi T, Endo H, Uchiyama T, Uchiyama S, Yamada E, Ohkubo H, Sakai E,

Takahashi H, Maeda S, Wada K, Natsumeda Y, Hippo Y, Nakajima A, Nakagama H.

Conditional knockout of the leptin receptor in the colonic epithelium revealed the

local effects of leptin receptor signaling in the progression of colonic tumors in mice.

Carcinogenesis. 2014 Sep;35(9):2134-41. doi: 10.1093/carcin/bgu135. Epub 2014 Jun

23.

403.Kessoku T, Yoneda M, Sumida Y, Eguchi Y, Fujii H, Hyogo H, Ono M, Kawaguchi T,

Nakajima A; Japan Study Group of NAFLD (JSG-NAFLD). Insulin Resistance

Correlated With the Severity of Liver Histology in Japanese NAFLD Patients: A

Multicenter Retrospective Study. J Clin Gastroenterol. 2014 Jul 10. [Epub ahead of

print] No abstract available.

404.Takahashi H, Ohkubo H, Nakajima A, Shinozaki M, Sato H Comparison of Clinical

Guidelines for Ulcerative Colitis: ECCO, BSG, US and Japanese Guidelines with

Reference to Surveillance Program JSM Gastroenterol Hepatol 2(3): 1023 (2014)

405.Chiba H, Takahashi A, Inamori M, Goto T, Ohata K, Matsuhashi N, Nakajima A.

Early colon cancer presenting as intussusception and successfully treated using

endoscopic submucosal dissection. Endoscopy. 2014;46 Suppl 1:E326-7. doi:

10.1055/s-0034-1377224. Epub 2014 Aug 4.

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406.Takihata M, Nakamura A, Aoki K, Kimura M, Sekino Y, Inamori M, Maeda S,

Gotoh E, Nakajima A, Terauchi Y.Comparison of intragastric balloon therapy and

intensive lifestyle modification therapy with respect to weight reduction and

abdominal fat distribution in super-obese Japanese patients. Obes Res Clin Pract.

2014 Jul-Aug;8(4):e331-8. doi: 10.1016/j.orcp.2013.07.002. Epub 2013 Aug 24.

407.Kessoku T, Ogawa Y, Yoneda M, Imajo K, Sumida Y, Eguchi Y, Fujii H, Hyogo H,

Ono M, Suzuki Y, Kawaguchi T, Chayama K, Tanaka S, Fujimoto K, Anzai K,

Saibara T, Sata M, Itoh Y, Nakajima A, Jsg-Nafld TO.Simple scoring system for

predicting cirrhosis in nonalcoholic fatty liver disease. World J Gastroenterol. 2014

Aug 7;20(29):10108-14. doi: 10.3748/wjg.v20.i29.10108.

408.Ichikawa Y, Nagashima Y, Morioka K, Akimoto K, Kojima Y, Ishikawa T, Goto A,

Kobayashi N, Watanabe K, Ota M, Fujii S, Kawamata M, Takagawa R, Kunizaki C,

Takahashi H, Nakajima A, Maeda S, Shimada H, Inayama Y, Ohno S, Endo I.

Colorectal laterally spreading tumors show characteristic expression of cell polarity

factors, including atypical protein kinase C λ/ι, E-cadherin, β-catenin and basement

membrane component. Oncol Lett. 2014 Sep;8(3):977-984. Epub 2014 Jun 20.

409.Fujisawa T, Kagawa K, Watanabe S, Hisatomi K, Kubota K, Sato H, Nakajima A,

Matsuhashi N. Endoscopic nasobiliary drainage for obstructive jaundice using

either a 5 Fr or 7 Fr catheter: a prospective, randomized trial. BMC Gastroenterol.

2014 Sep 18;14(1):161. [Epub ahead of print] PubMed PMID: 25234181.

410.Yoneda M, Imajo K, Saito S, Nakajima A. Screening of nonalcoholic fatty liver

disease in patients with coronary heart disease by transient elastography: proceed

with caution Wiener klinische Wochenschrift Accepted 28 September 2014

411.Yamada E, Inamori M, Uchida E, Tanida E, Izumi M, Takeshita K, Fujii T, Komatsu

K, Hamanaka J, Maeda S, Kanesaki A, Matsuhashi N, Nakajima A. Association

Between the Location of Diverticular Disease and the Irritable Bowel Syndrome: A

Multicenter Study in Japan. Am J Gastroenterol. 2014 Dec;109(12):1900-5. doi:

10.1038/ajg.2014.323. Epub 2014 Oct 21.

412.Taniguchi L, Higurashi T, Uchiyama T, Kondo Y, Uchida E, Uchiyama S, Jono F,

Hamanaka J, Kuriyama H, Hata Y, Endo H, Takahashi H, Nagase H, Matsuhashi N,

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Nakajima A. Metabolic factors accelerate colorectal adenoma recurrence. BMC

Gastroenterol. 2014 Oct 23;14:187. doi: 10.1186/1471-230X-14-187.

413.Ida T, Inamori M, Hamanaka J, Chiba H, Kusakabe A, Morohashi T, Nakajima A,

Maeda S, Goto T. Endoscopic removal of a migrated stent in the gallbladder.

Endoscopy. 2014;46 Suppl 1:E539-40. doi: 10.1055/s-0034-1377634. Epub 2014 Nov

19. No abstract available.

414.Sakai E, Endo H, Taguri M, Kawamura H, Taniguchi L, Hata Y, Ezuka A, Nagase

H,Kessoku T, Ishii K, Arimoto J, Yamada E, Ohkubo H, Higurashi T, Koide T,

Nonaka T, Takahashi H, Nakajima A. Frequency and risk factors for rebleeding

events in patients with small bowel angioectasia. BMC Gastroenterol. 2014 Nov

28;14(1):200.[Epub ahead of print] PubMed PMID: 25430814.

415.Yamada E, Inamori M, Watanabe S, Sato T, Tagri M, Uchida E, Tanida E, Izumi

M,Takeshita K, Fujisawa N, Komatsu K, Hamanaka J, Kanesaki A, Matsuhashi

N,Nakajima A. Constipation is not associated with colonic diverticula: amulticenter

study in Japan. 2014 Dec 3. doi:10.1111/nmo.12478. [Epub ahead of print] PubMed

PMID: 25469640.

416.Muto M, Matsufuji H, Tomomasa T, Nakajima A, Kawahara H, Ida S, Ushijima

K,Kubota A, Mushiake S, Taguchi T. Pediatric chronic intestinal pseudo-obstruction

is a rare, serious, and intractable disease: A report of a nationwide survey in Japan.

J Pediatr Surg. 2014 Dec;49(12):1799-803. doi: 10.1016/j.jpedsurg.2014.09.025.

Epub 2014 Nov 6. PubMed PMID: 25487487.

417.Kusakabe A, Nonaka T, Sekino Y, Iida H, Endo H, Koide T, Takahashi H, Fujita K,

Yoneda M, Goto A, Gotoh E, Maeda S, Nakajima A, Nosaka C, Inamori M. Effects of

ramosetron oral disintegrating tablets on gastric emptying: crossover study using

the 13C-acetic acid breath test. Hepatogastroenterology. 2014

Jul-Aug;61(133):1279-82.

418.Kobayashi N, Sato T, Kato S, Watanabe S, Hosono K, Kubota K, Takedaz K, Endo I,

Nakajima A, Maeda S, Ichikawa Y. Endoscopic treatment of postoperative benign

bile duct stricture compared with malignant bile duct stricture.

Hepatogastroenterology. 2014 Sep;61(134):1507-18.

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419.Inamori M, Togawa J, Matsumoto S, Harad K, Matsuura M, Iida H, Akimoto K,

Endo H, Nonaka T, Takahashi H, Koide T, Shibata W, Ida T, Kusakabe A, Nagase H,

Tominaga S, Tanaka K, Gotoh E, Nakajima A, Maeda S. Protective effect of

lactoferrin on acute acid reflux-induced esophageal mucosal damage.

Hepatogastroenterology. 2014 Sep;61(134):1595-600.

420.Endo H, Sakai E, Kato T, Umezawa S, Higurashi T, Ohkubo H, Nakajima A. Small

bowel injury in low-dose aspirin users. J Gastroenterol. 2014 Dec 14. [Epub ahead of

print]

421.Imajo K, Hyogo H, Yoneda M, Honda Y, Kessoku T, Tomeno W, Ogawa Y, Taguri M,

Mawatari H, Nozaki Y, Fujita K, Kirikoshi H, Saito S, Sumida Y, Ono M, Wada K,

Nakajima A, Eguchi Y. LDL-Migration Index (LDL-MI), an Indicator of Small Dense

Low-Density Lipoprotein (sdLDL), Is Higher in Non-Alcoholic Steatohepatitis than

in Non-Alcoholic Fatty Liver: A Multicenter Cross-Sectional Study. PLoS One. 2014

Dec 26;9(12):e115403. doi: 10.1371/journal.pone.0115403. eCollection 2014.

422.Matsuura M, Inamori M, Endo H, Matsuura T, Kanoshima K, Inoh Y, Fujita Y,

Umezawa S, Fuyuki A, Uchiyama S, Higurashi T, Ohkubo H, Sakai E, Iida H,

Nonaka T, Futagami S, Kusakabe A, Maeda S, Nakajima A. Lubiprostone

decreases the small bowel transit time by capsule endoscopy: an exploratory,

randomised, double-blind, placebo-controlled 3-way crossover study. Gastroenterol

Res Pract. 2014;2014:879595. doi: 10.1155/2014/879595. Epub 2014 Dec 29.

423.Tomeno W, Kawashima K, Yoneda M, Saito S, Ogawa Y, Honda Y, Kessoku T, Imajo

K, Mawatari H, Fujita K, Saito S, Hirayasu Y, Nakajima A. Nonalcoholic fatty liver

disease comorbid with major depressive disorder: the pathological features and poor

therapeutic efficacy. J Gastroenterol Hepatol. 2015 Jun;30(6):1009-14. doi:

10.1111/jgh.12897.

424.Kobayashi N, Watanabe S, Hosono K, Kubota K, Nakajima A, Kaneko T, Sugimori

K, Tokuhisa M, Goto A, Mori R, Taniguchi K, Matsuyama R, Endo I, Maeda S,

Ichikawa Y. Endoscopic inside stent placement is suitable as a bridging treatment

for preoperative biliary tract cancer. BMC Gastroenterol. 2015 Feb 5;15(1):8. [Epub

ahead of print]

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425.Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M, Takei Y,

Takehara T, Tokushige K, Nakajima A, Yoneda M, Saibara T, Shiota G, Sakaida I,

Nakamuta M, Mizuta T, Tsubouchi H, Sugano K, Shimosegawa T. Evidence-based

clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic

steatohepatitis. J Gastroenterol. 2015 Apr;50(4):364-77. doi:

10.1007/s00535-015-1050-7. Epub 2015 Feb 24.

426.Nonaka T, Inamori M, Endo H, Matsuura M, Uchiyama S, Yamada E, Sekino Y,

Sakai E, Higurashi T, Ohkubo H, Akimoto K, Iida H, Takahashi H, Koide T, Shibata

W, Ida T, Kusakabe A, Gotoh E, Nakajima A, Maeda S. Correlation between gastric

transit time measured by video capsule endoscopy and gastric emptying determined

by the continuous real-time 13C breath test (BreathID system).

Hepatogastroenterology. 2014 Oct;61(135):2159-62.

427.Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Imajo K, Saito S, Yoneda M, Nakamura

T, Nakajima A, Hotta K. Targeted-bisulfite sequence analysis of the methylation of

CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with

nonalcoholic fatty liver disease. J Hepatol. 2015 Aug;63(2):494-502. doi:

10.1016/j.jhep.2015.02.049. Epub 2015 Mar 14.

428.Kitamoto A, Kitamoto T, So R, Matsuo T, Nakata Y, Hyogo H, Ochi H, Nakamura T,

Kamohara S, Miyatake N, Kotani K, Mineo I, Wada J, Ogawa Y, Yoneda M,

Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama

K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Sakata T, Tanaka K,

Matsuzawa Y, Hotta K. ADIPOQ polymorphisms are associated with insulin

resistance in Japanese women. Endocr J. 2015;62(6):513-21. doi:

10.1507/endocrj.EJ14-0574. Epub 2015 Mar 31.

429.Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M, Takei Y,

Takehara T, Tokushige K, Nakajima A, Yoneda M, Saibara T, Shiota G, Sakaida I,

Nakamuta M, Mizuta T, Tsubouchi H, Sugano K, Shimosegawa T. Evidence-based

clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic

steatohepatitis. Hepatol Res. 2015 Apr;45(4):363-77. doi: 10.1111/hepr.12511.

430.Inoue S, Sakamoto Y, Sekino Y, Nonaka T, Iida H, Endo H, Koide T, Takahashi H,

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Maeda S, Nakajima A, Gotoh E, Inamori M. Low-dose ramosetron accelerates

gastric emptying in the early phase: A crossover study in healthy volunteers using a

continuous real-time 13C breath test (BreathID System). Turk J Gastroenterol.

2015 Mar;26(2):123-7. doi: 10.5152/tjg.2015.4768.

431.Nozaki Y, Fujita K, Wada K, Yoneda M, Kessoku T, Shinohara Y, Imajo K, Ogawa Y,

Nakamuta M, Saito S, Masaki N, Nagashima Y, Terauchi Y, Nakajima A. Deficiency

of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in

non-alcoholic steatohepatitis mouse model. BMC Gastroenterol. 2015 Apr 1;15:42.

doi: 10.1186/s12876-015-0269-3.

432.Koide T, Iinuma M, Sakai E, Yamada E, Higurashi T, Ohkubo H, Iida H, Hosono K,

Endo H, Nonaka T, Fujita K, Takahashi H, Yoneda M, Goto A, Ida T, Kusakabe A,

Nakajima A, Maeda S, Gotoh E, Inamori M. Percutaneus endoscopic gastrostomy in

a patient with hemophilia A. Turk J Gastroenterol. 2014 Dec;25 Suppl 1:S241. doi:

10.5152/tjg.2014.5262. No abstract available.

433.Suzuki K, Akimoto K, Fujisawa N, Koyama S, Tsunemi A, Tanaka M, Sekino Y, Iida

H, Nonaka T, Nakajima A, Maeda S, Gotoh E, Inamori M. A metastatic melanoma of

the small intestine diagnosed by single-balloon enteroscopy. Turk J Gastroenterol.

2014 Dec;25 Suppl 1:S262-3. doi: 10.5152/tjg.2014.4113. No abstract available.

434.Oshima A, Hosono K, Ito S, Sekino Y, Iida H, Nonaka T, Yamanaka S, Nakajima A,

Maeda S, Gotoh E, Inamori M. Ischemic gastritis. Turk J Gastroenterol. 2014

Dec;25 Suppl 1:S289-90. doi: 10.5152/tjg.2014.4114. No abstract available.

435.Umezawa S, Higurashi T, Uchiyama S, Sakai E, Ohkubo H, Endo H, Nonaka T,

Nakajima A. Visual distraction alone for the improvement of colonoscopy-related

pain and satisfaction. World J Gastroenterol. 2015 Apr 21;21(15):4707-14. doi:

10.3748/wjg.v21.i15.4707.

436.Iida H, Inamori M, Okuno K, Sekino Y, Sakai E, Okubo H, Higurashi T, Endo H,

Hosono K, Yoneda M, Koide T, Takahashi H, Goto A, Kubota K, Saito S, Maeda S,

Nakajima A, Gotoh E.Early effects of oral administration of esomeprazole and

omeprazole on the intragastric pH. Hepatogastroenterology. 2015

Mar-Apr;62(138):493-6.

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437.Matsuura M, Inamori M, Nakajima A, Komiya Y, Inoh Y, Kawasima K, Naitoh M,

Fujita Y, Eduka A, Kanazawa N, Uchiyama S, Tani R, Kawana K, Ohtani S, Nagase

H. Effectiveness of therapeutic barium enema for diverticular hemorrhage. World J

Gastroenterol. 2015 May 14;21(18):5555-9. doi: 10.3748/wjg.v21.i18.5555.

438.Yamada A, Horimatsu T, Okugawa Y, Nishida N, Honjo H, Ida H, Kou T, Kusaka T,

Sasaki Y, Makato Y, Higurashi T, Yukawa N, Amanuma Y, Kikuchi O, Muto M, Ueno

Y, Nakajima A, Chiba T, Boland CR, Goel A. Serum miR-21, miR-29a and miR-125b

are promising biomarkers for the early detection of colorectal neoplasia. Clin Cancer

Res. 2015 Sep 15;21(18):4234-42. doi: 10.1158/1078-0432.CCR-14-2793. Epub 2015

Jun 2.

439.Imajo K, Yoneda M, Nakajima A. Are platelets count useful for detecting the grade

of steatosis? Hepat Mon. 2015 May 23;15(5):e28957. doi:

10.5812/hepatmon.15(5)2015.28957. eCollection 2015 May. No abstract available.

440.Chiba H, Ashikari K, Takahashi A, Goto T, Ohata K, Matsuhashi N, Nakajima A. A

case of delayed bleeding after endoscopic submucosal dissection for completely

circumferential esophageal cancer. Endoscopy. 2015;47 Suppl 1:E385-6. doi:

10.1055/s-0034-1392429. Epub 2015 Aug 14. PubMed PMID: 26273773.

441.Fujisawa T, Kagawa K, Ochiai K, Hisatomi K, Kubota K, Sato H, Nakajima A,

Matsuhashi N. Prophylactic Efficacy of 3 or 5-cm Pancreatic Stents for Preventing

Post-ERCP Pancreatitis: A Prospective, Randomized Trial. J Clin Gastroenterol.

2016 Mar;50(3):e30-4.2015 Aug 12. [Epub ahead of print] PubMed PMID: 26280707.

442.Hirotani A, Sakai E, Nakajima A, Kawana K, Nagase H. Endoscopic findings of

atypical juvenile colonic polyps. Gastrointest Endosc. 2016 Feb;83(2):476-7. doi:

10.1016/j.gie.2015.08.032. Epub 2015 Aug 20

443.Kitamoto A, Kitamoto T, Nakamura T, Matsuo T, Nakata Y, Hyogo H, Ochi H,

Kamohara S, Miyatake N, Kotani K, Mineo I, Wada J, Ogawa Y, Yoneda M,

Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama

K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Sakata T, Tanaka K,

Matsuzawa Y, Hotta K. CDH13 Polymorphisms are Associated with Adiponectin

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Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass. J

Atheroscler Thromb. 2016 Mar 1;23(3):309-19. doi: 10.5551/jat.31567. Epub 2015

Oct 1.

444.Tokushige K, Hyogo H, Nakajima T, Ono M, Kawaguchi T, Honda K, Eguchi Y,

Nozaki Y, Kawanaka M, Tanaka S, Imajo K, Sumida Y, Kamada Y, Fujii H, Suzuki Y,

Kogiso T, Karino Y, Munekage K, Kuromatsu R, Oeda S, Yanase M, Mori K, Ogawa Y,

Seko Y, Takehara T, Itoh Y, Nakajima A, Kanemasa K, Nishino K, Masaki N,

Takahashi H, Seike M, Torimura T, Saibara T, Toyota J, Chayama K, Hashimoto E.

Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease

and alcoholic liver disease: multicenter survey. J Gastroenterol. 2016

Jun;51(6):586-96. doi: 10.1007/s00535-015-1129-1. Epub 2015 Oct 11.

445.Arimoto J, Endo H, Kato T, Umezawa S, Fuyuki A, Uchiyama S, Higurashi T,

Ohkubo H, Nonaka T, Takeno M, Ishigatsubo Y, Sakai E, Matsuhashi N, Nakajima

A. Clinical value of capsule endoscopy for detecting the small bowel lesions in

patients with intestinal Behçet's disease. Dig Endosc. 2016 Mar;28(2):179-85. doi:

10.1111/den.12552. Epub 2015 Oct 28.

446.Tarao K, Sekino Y, Nonaka T, Iida H, Inamori M, Nakajima A, Maeda S,

Natsumeda Y, Ikegami T, Ohshige K. Recent Trends in Colonic Diverticulosis in

Yokohama City: A Possibility of Changing to a More Western Profile. Intern Med.

2015;54(20):2545-50. doi: 10.2169/internalmedicine.54.4813. Epub 2015 Oct 15.

447.Nonaka T, Inamori M, Miyashita T, Harada S, Inou Y, Kanoshima K, Matsuura M,

Higurashi T, Ohkubo H, Iida H, Endo H, Kusakabe A, Maeda S, Gotoh T, Nakajima

A. Feasibility of deep sedation with the combination of propofol and

dexmedetomidine hydrochloride for esophageal endoscopic submucosal dissection.

Dig Endosc. 2016 Mar;28(2):145-51. doi: 10.1111/den.12559. Epub 2015 Nov 9.

448.Ezuka A, Sakai E, Kawana K, Nagase H, Kakuta Y, Uchiyama S, Ohkubo H,

Higurashi T, Nonaka T, Endo H, Takahashi H, Nakajima A.:Association between

factors associated with colorectal cancer and rectal aberrant crypt foci in humans.

Oncol Lett. 2015 Dec;10(6):3689-3695. Epub 2015 Sep 29.

449.Sakai E, Fukuyo M, Ohata K, Matsusaka K, Doi N, Mano Y, Takane K, Abe H, Yagi

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K, Matsuhashi N, Fukushima J, Fukayama M, Akagi K, Aburatani H, Nakajima A,

Kaneda A. Genetic and epigenetic aberrations occurring in colorectal tumors

associated with serrated pathway. Int J Cancer. 2016 Apr 1;138(7):1634-44. doi:

10.1002/ijc.29903. Epub 2015 Nov 12.

450.Manabe N, Haruma K, Nakajima A, Yamada M, Maruyama Y, Gushimiyagi M,

Yamamoto T. Characteristics of Colonic Diverticulitis and Factors Associated With

Complications: A Japanese Multicenter, Retrospective, Cross-Sectional Study. Dis

Colon Rectum. 2015 Dec;58(12):1174-81. doi: 10.1097/DCR.0000000000000488.

PubMed PMID: 26544815.

451.Imajo K, Kessoku T, Honda Y, Tomeno W, Ogawa Y, Mawatari H, Fujita K, Yoneda

M, Taguri M, Hyogo H, Sumida Y, Ono M, Eguchi Y, Inoue T, Yamanaka T, Wada K,

Saito S, Nakajima A. Magnetic Resonance Imaging More Accurately Classifies

Steatosis and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease Than

Transient Elastography. Gastroenterology. 2016 Mar;150(3):626-637.e7. doi:

10.1053/j.gastro.2015.11.048. Epub 2015 Dec 8.

452.Nozaki Y, Fujita K, Wada K, Yoneda M, Shinohara Y, Imajo K, Ogawa Y, Kessoku T,

Nakamuta M, Saito S, Masaki N, Nagashima Y, Terauchi Y, Nakajima A. Deficiency

of eNOS exacerbates early-stage NAFLD pathogenesis by changing the fat

distribution. BMC Gastroenterol. 2015 Dec 17;15(1):177. doi:

10.1186/s12876-015-0409-9.

453.Honda Y, Imajo K, Kato T, Kessoku T, Ogawa Y, Tomeno W, Kato S, Mawatari H,

Fujita K, Yoneda M, Saito S, Nakajima A. The Selective SGLT2 Inhibitor

Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice.

PLoS One. 2016 Jan 5;11(1):e0146337. doi: 10.1371/journal.pone.0146337.

eCollection 2016.

454.Honda Y, Yoneda M, Kessoku T, Ogawa Y, Tomeno W, Imajo K, Mawatari H, Fujita

K, Hyogo H, Ueno T, Chayama K, Saito S, Nakajima A, Hotta K. The characteristics

of non-obese NAFLD: Effect of genetic and environmental factors. Hepatol Res. 2016

Sep;46(10):1011-8. doi: 10.1111/hepr.12648. Epub 2016 Apr 5.

455.Fujisawa T, Kagawa K, Hisatomi K, Kubota K, Sato H, Nakajima A, Matsuhashi

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N:Obesity with abundant subcutaneous adipose tissue increases the risk of

post-ERCP pancreatitis. J Gastroenterol. 2016 Sep;51(9):931-8. doi:

10.1007/s00535-016-1160-x. Epub 2016 Jan 20.

456.Nonaka T, Inamori M, Kanoshima K, Ohkuma K, Inoh Y, Matsuura M, Fuyuki A,

Uchiyama S, Higurashi T, Ohkubo H, Iida H, Endo H, Tateishi Y, Kusakabe A,

Ohashi K, Maeda S, Nakajima A. Evaluation of endoscopic findings for

discriminating between early carcinomas and low-grade adenomas in superficial

elevated gastric lesions. Turk J Gastroenterol. 2016 Mar;27(2):108-14. doi:

10.5152/tjg.2015.150359. Epub 2016 Feb 5.

457.Kessoku T, Imajo K, Honda Y, Kato T, Ogawa Y, Tomeno W, Kato S, Mawatari H,

Fujita K, Yoneda M, Nagashima Y, Saito S, Wada K, Nakajima A. Resveratrol

ameliorates fibrosis and inflammation in a mouse model of nonalcoholic

steatohepatitis. Sci Rep. 2016 Feb 25;6:22251. doi: 10.1038/srep22251.

458.Higurashi T, Hosono K, Takahashi H, Komiya Y, Umezawa S, Sakai E, Uchiyama T,

Taniguchi L, Hata Y, Uchiyama S, Hattori A, Nagase H, Kessoku T, Arimoto J,

Matsuhashi N, Inayama Y, Yamanaka S, Taguri M, Nakajima A. Metformin for

chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy

patients without diabetes: a multicentre double-blind, placebo-controlled,

randomised phase 3 trial. Lancet Oncol. 2016 Apr;17(4):475-83. doi:

10.1016/S1470-2045(15)00565-3. Epub 2016 Mar 3.

459.Yoneda M, Thomas E, Schiff ER:Reply:Supersonic Shear Imaging and Transient

Elastography in obesity. Clin Gastroenterol Hepatol. 2016 Mar;14(3):484-5. doi:

10.1016/j.cgh.2015.12.009. Epub 2015 Dec 9.

460.Sakai E, Fukuyo M, Matsusaka K, Ohata K, Doi N, Takane K, Matsuhashi N,

Fukushima J, Nakajima A, Kaneda A : TP53 mutation at early stage of colorectal

cancer progression from two types of laterally spreading tumors. Cancer Sci, 2016

Jun;107(6):820-7. doi: 10.1111/cas.12930. Epub 2016 Apr 27.

461.Tamura K, Kawai Y, Kiguchi T, Okamoto M, Kaneko M, Maemondo M, Gemba K,

Fujimaki K, Kirito K, Goto T, Fujisaki T, Takeda K, Nakajima A, Ueda T : Efficacy

and safety of febuxostat for prevention of tumor lysis syndrome in patients with

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malignant tumors receiving chemotherapy: a phase III, randomized, multi-center

trial comparing febuxostat and allopurinol. Int J Clin Oncol, 2016

Oct;21(5):996-1003. Epub 2016 Mar 26.

462.Sekino Y, Nakajima A, Kubota K : Successful endoscopic papillectomy in patient

with situs inversus. Dig Endosc. 2016 Jul;28(5):616. doi: 10.1111/den.12662. No

abstract available..

463.Endo H, Kato T, Sakai E, Taniguchi L, Arimoto J, Kawamura H, Higurashi T,

Ohkubo H, Nonaka T, Taguri M, Inamori M, Yamanaka T, Sakaguchi T, Hata Y,

Nagase H, Nakajima A: Is a fecal occult blood test a useful tool for judging whether

to perform capsule endoscopy in low-dose aspirin users with negative colonoscopy

and esophagogastroduodenoscopy? J Gastroenterol. 2017 Feb;52(2):194-202. doi:

10.1007/s00535-016-1212-2. Epub 2016 Apr 19.

464.Yamada E, Tsunoda S, Abe T, Uchida E, Teraoka H, Watanabe S, Kawana I, Tagri

M, Hosaka N, Nagai K, Nishino H, Nakajima A. Factors associated with poor

therapeutic response in outpatients with irritable bowel syndrome: a multicenter

study in Japan. J Gastroenterol. 2017 Mar;52(3):301-307. doi:

10.1007/s00535-016-1215-z. Epub 2016 Apr 29.

465.Yoneda M, Hyun J, Jakubski S, Saito S, Nakajima A, Schiff ER, Thomas E.

Hepatitis B Virus and DNA Stimulation Trigger a Rapid Innate Immune Response

through NF-κB. J Immunol. 2016 Jul 15;197(2):630-43. doi:

10.4049/jimmunol.1502677. Epub 2016 Jun 10.

466.Kubota K, Hasegawa S, Iwasaki A, Sato T, Fujita Y, Hosono K, Nakajima A, Mori R,

Matsuyama R, Endo I: Stent placement above the sphincter of Oddi permits

implementation of neoadjuvant chemotherapy in patients with initially

unresectable Klatskin tumor. Endosc Int Open. 2016 Apr;4(4):E427-33. doi:

10.1055/s-0042-102246. Epub 2016 Mar 30.

467.Imajo K, Nakajima A: Reply. Gastroenterology. 2016 Aug;151(2):375-6. doi:

10.1053/j.gastro.2016.06.046. Epub 2016 Jul 1. No abstract available.

468.Arimoto J, Horita N, Kato S, Fuyuki A, Higurashi T, Ohkubo H, Endo H, Takashi N,

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Kaneko T, Nakajima A: Diagnostic test accuracy of glutamate dehydrogenase for

Clostridium difficile: Systematic review and meta-analysis. Sci Rep. 2016 Jul

15;6:29754. doi: 10.1038/srep29754.

469.Uchida K, Nakajima A, Ushijima K, Ida S, Seki Y, Kakuta F, Abukawa D,

Tsukahara H, Maisawa SI, Inoue M, Araki T, Umeno J, Matsumoto T, Taguchi T.

Pediatric Onset Chronic Nonspecific Multiple Ulcers of Small Intestine: A

Nationwide Survey and Genetic Study in Japan. J Pediatr Gastroenterol Nutr. 2017

Apr;64(4):565-568. doi: 10.1097/MPG.0000000000001321.

470.Fujisawa T, Kagawa K, Hisatomi K, Kubota K, Nakajima A, Matsuhashi N. Is

endoscopic papillary balloon dilatation really a risk factor for post-ERCP

pancreatitis? World J Gastroenterol. 2016 Jul 14;22(26):5909-16. doi:

10.3748/wjg.v22.i26.5909. Review.

471.Kudo C, Kessoku T, Kamata Y, Hidaka K, Kurihashi T, Iwasaki T, Takashiba S,

Kodama T, Tamura T, Nakajima A, Minabe M : Relationship between non-alcoholic

fatty liver disease and periodontal disease: a review and study protocol on the effect

of periodontal treatment on non-alcoholic fatty liver disease. Journal of

Translational Science. 2016 Volume 2(6): 340-345. doi: 10.15761/JTS.1000160.

472.Fujita Y, Iwasaki A, Sato T, Fujisawa T, Sekino Y, Hosono K, Matsuhashi N,

Sakamaki K3, Nakajima A, Kubota K : Feasibility of Endoscopic Papillary Large

Balloon Dilation in Patients with Difficult Bile Duct Stones without Dilatation of

the Lower Part of the Extrahepatic Bile Duct. Gut Liver. 2017 Jan 15;11(1):149-155.

doi: 10.5009/gnl15634.

473. Fuyuki A, Ohkubo H, Higurashi T, Iida H, Inoh Y, Inamori M, Nakajima A :

Clinical importance of cine-MRI assessment of small bowel motility in patients with

chronic intestinal pseudo-obstruction: a retrospective study of 33 patients. J

Gastroenterol. 2016 Aug 22. [Epub ahead of print]

474.Fujita Y, Hasegawa S, Kato Y, Ishii K, Iwasaki A, Sato T, Sekino Y, Hosono K,

Nakajima A, Kubota K: Intravenous injection of low-dose flurbiprofen axetil for

preventing post-ERCP pancreatitis in high-risk patients: An interim analysis of the

trial. Endosc Int Open. 2016 Oct;4(10):E1078-E1082.

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475.Nonaka T, Inamori M, Honda Y, Kanoshima K, Inoh Y, Matsuura M, Uchiyama S,

Sakai E, Higurashi T, Ohkubo H, Iida H, Endo H, Fujita K, Kusakabe A, Atsukawa

K, Takahashi H, Tateishi Y, Maeda S, Ohashi K, Nakajima A: Can magnifying

endoscopy with narrow-band imaging discriminate between carcinomas and low

grade adenomas in gastric superficial elevated lesions? Endosc Int Open. 2016

Nov;4(11):E1203-E1210.

476.Arimoto J, Higurashi T, Kato S, Goto S, Suzuki S, Nakajima A, Atsukawa

K.Cardiac tumors and gastroendoscopy: endoscopic resection of left ventricular

tumors.Endoscopy. 2017 Feb;49(S 01):E23-E24. doi: 10.1055/s-0042-122139. No

abstract available

477.Honda Y, Kessoku T, Ogawa Y, Tomeno W, Imajo K, Fujita K, Yoneda M, Takizawa T,

Saito S, Nagashima Y, Nakajima A:Pemafibrate, a novel selective peroxisome

proliferator-activated receptor alpha modulator, improves the pathogenesis in a

rodent model of nonalcoholic steatohepatitis.Sci Rep. 2017 Feb 14;7:42477. doi:

10.1038/srep42477.

478.Yamada E, Watanabe S, Nakajima A. Associations of Mental Health and Physical

Function with Colonoscopy-related Pain. Intern Med. 2017;56(4):383-388.

doi:10.2169/internalmedicine.56.7465. PubMed PMID: 28202858.

479.Hotta K, Kikuchi M, Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Kessoku T,

Kobayashi K, Yoneda M, Imajo K, Tomeno W, Nakaya A, Suzuki Y, Saito S,

Nakajima A. Identification of core gene networks and hub genes associated with

progression of nonalcoholic fatty liver disease by RNA sequencing. Hepatol Res.

2017 Feb 20. doi: 10.1111/hepr.12877. [Epub ahead of print] PubMed PMID:

28219123.

480.Sakai E, Higurashi T, Ohkubo H, Hosono K, Ueda A, Matsuhashi N, Nakajima A:

Investigation of Small Bowel Abnormalities in HIV-Infected Patients Using Capsule

Endoscopy. Gastroenterol Res Pract, Epub 2017 Mar 20.

481.Kato T, Honda Y, Kurita Y, Iwasaki A, Sato T, Kessoku T, Uchiyama S, Ogawa Y,

Ohkubo H, Higurashi T, Yamanaka T, Usuda H, Wada K, Nakajima A: Lubiprostone

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improves intestinal permeability in humans, a novel therapy for the leaky gut: A

prospective randomized pilot study in healthy volunteers. PLoS One, 2017 Apr

14;12(4):e0175626.

482.Fujii T, Sakai E, Takahashi H , Yamada E, Ohkubo H, Higurashi T, Nakajima A:

The distribution of human rectal aberrant crypt foci and criteria for defining the

counting area. Oncology Letters. 2017 Jun;13(6):4501-4504.

doi:10.3892/ol.2017.6003. Epub 2017 Apr 7. PubMed PMID: 28599450; PubMed

Central PMCID: PMC5452945.

483.Yamada E, Kuriyama H, Uchida E, Murata Y, Hata Y, Tagri M, Isozaki Y, Oyamada

H, Ozawa Y, Ito T, Mizuki A, Inamori M, Manabe N, Haruma K, Nakajima A :

Association between endoscopic findings related to colonic diverticula and bowel

habits: a multicenter study in Japan. J Gastroenterol Hepatol. 2017 Apr 19. doi:

10.1111/jgh.13805. [Epub ahead of print] PubMed PMID: 28425144.

484.Hasegawa S, Kobayashi N, Tokuhisa M, Goto A, Takano S, Takada Y, Kaneta T,

Mori R, Matsuyama R, Endo I, Yamanaka S, Nakajima A, Inoue T, Ichikawa Y.

Clinical Usefulness of Somatostatin Receptor Scintigraphy in Japanese Patients

with Gastroenteropancreatic Neuroendocrine Tumors. Digestion. 2017 Jun

14;96(1):13-20. doi: 10.1159/000470838. [Epub ahead of print] PubMed PMID:

28609761

485.Ohkubo H, Fuyuki A, Arimoto J, Higurashi T, Nonaka T, Inoh Y, Iida H, Inamori M,

Kaneda T, Nakajima A. Efficacy of percutaneous endoscopic gastro-jejunostomy

(PEG-J) decompression therapy for patients with chronic intestinal

pseudo-obstruction (CIPO). Neurogastroenterol Motil. 2017 Jun 20.

doi:10.1111/nmo.13127. [Epub ahead of print] PubMed PMID: 28631871.

486.Umezawa S, Higurashi T, Nakajima A: AMPK: therapeutic target for diabetes and

cancer prevention. Curr Pharm Des. 2017 Jul 13. doi: 10.2174/

0929867324666170713150440. [Epub ahead of print] PubMed PMID: 28714409.

487.Niikura R, Yamada A, Maki K, Nakamura M, Watabe H, Fujishiro M, Oka S, Esaki

M, Fujimori S, Nakajima A, Ohmiya N, Matsumoto T, Tanaka S, Koike K, Sakamoto

C. Associations between drugs and small-bowel mucosal bleeding: A multicenter

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capsule-endoscopy study. Dig Endosc. 2017 Jul 18. doi: 10.1111/den.12922. [Epub

ahead of print] PubMed PMID: 28719079.

488.Chiba H, Tachikawa J, Kurihara D, Ashikari K, Takahashi A, Kuwabara H,

Nakaoka M, Morohashi T, Goto T, Ohata K, Nakajima A. Successful endoscopic

submucosal dissection of colon cancer with severe fibrosis after tattooing. Clin J

Gastroenterol. 2017 Aug 7. doi: 10.1007/s12328-017-0770-z. [Epub ahead of print]

PubMed PMID: 28785991.

489.Honda Y, Kessoku T, Sumida Y, Kobayashi T, Kato T, Ogawa Y, Tomeno W, Imajo

K,Fujita K, Yoneda M, Kataoka K, Taguri M, Yamanaka T, Seko Y, Tanaka S, Saito S,

Ono M, Oeda S, Eguchi Y, Aoi W, Sato K, Itoh Y, Nakajima A. Efficacy of glutathione

for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm,

multicenter, pilot study. BMC Gastroenterol. 2017 Aug 8;17(1):96. doi:

10.1186/s12876-017-0652-3. PubMed PMID: 28789631.

490.Nakajima A, Seki M, Taniguchi S. Determining an optimal clinical dose of

elobixibat, a novel inhibitor of the ileal bile acid transporter, in Japanese patients

with chronic constipation: a phase II, multicenter, double-blind, placebo-controlled

randomized clinical trial. J Gastroenterol. 2017 Aug 24. doi:

10.1007/s00535-017-1383-5. [Epub ahead of print] PubMed PMID: 28840422.

491.Oeda S, Takahashi H, Yoshida H, Ogawa Y, Imajo K, Yoneda M, Koshiyama Y, Ono

M, Hyogo H, Kawaguchi T, Fujii H, Nishino K, Sumida Y, Tanaka S, Kawanaka M,

Torimura T, Saibara T, Kawaguchi A, Nakajima A, Eguchi Y; Japan Study Group for

NAFLD (JSG-NAFLD):Prevalence of pruritus in patients with chronic liver

disease:a multicenter study. Hepatol Res. 2017 Sep 6. doi: 10.1111/hepr.12978.

[Epub ahead of print] PubMed PMID: 28877392.

492.Yamada E, Namiki Y, Takano Y, Takamine H, Inazumi K, Sasaki H, Yamada M, Ito

S, Iwasaki T, Mantani N, Minami T, Osada UN, Terauchi Y, Nakajima A:Clinical

factors associated with the symptoms of constipation in patients with diabetes

mellitus: a multicenter study. J Gastroenterol Hepatol. 2017 Oct 19. doi:

10.1111/jgh.14022.

493.Hotta K, Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Kessoku T, Yoneda M, Imajo

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K, Tomeno W, Saito S, Nakajima A: Identification of the genomic region under

epigenetic regulation during nonalcoholic fatty liver disease progression. Hepatol

Res. 2017 Oct 23. doi: 10.1111/hepr.12992.

494.Uchiyama T, Higurashi T, Kuriyama H, Kondo Y, Hata Y, Nakajima A. Oral

esomeprazole vs injectable omeprazole for the prevention of hemorrhage after

endoscopic submucosal dissection. World J Gastrointest Endosc. 2017 Oct

16;9(10):514-520. doi: 10.4253/wjge.v9.i10.514. PubMed PMID: 29085562; PubMed

Central PMCID: PMC5648994.

495.Yoneda M, Imajo K, Takahashi H, Ogawa Y, Eguchi Y, Sumida Y, Yoneda M,

Kawanaka M, Saito S, Tokushige K, Nakajima A. Clinical strategy of diagnosing

and following patients with nonalcoholic fatty liver disease based on invasive and

noninvasive methods. J Gastroenterol. 2017 Nov 24. doi: 10.1007/s00535-017-1414-2.

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496.Arimoto J, Higurashi T, Chiba H, Misawa N, Yoshihara T, Kato T, Kanoshima K,

Fuyuki A, Ohkubo H, Goto S, Ishikawa Y, Tachikawa J, Ashikari K, Nonaka T,

Taguri M, Kuriyama H, Atsukawa K, Nakajima A. Continued Use of a Single

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497.Fukudo S, Nakajima A, Fujiyama Y, Kosako M, Nakagawa A, Akiho H, Nakashima

Y, Johnston JM, Miwa H. Determining an optimal dose of linaclotide for use in

Japanese patients with irritable bowel syndrome with constipation: A phase II

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498.W.-K. Chan, S. Treeprasertsuk, Imajo K, Nakajima A, Seki Y, Kasama K, Kakizaki

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Therapeutics, 2018;1–10. Received: 8 July 2017 | First decision: 6 August 2017 |

Accepted: 16 December 2017