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Mitra Dutta, PhD

Vice Chancellor for Research

NEW FACULTY ORIENTATION

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Office of the Vice Chancellor for Research

Institutional Official (IO) is the University point of contact with various agencies, the signatory for the Federal-wide Assurance (FWA), and bears ultimate responsibility for ensuring University compliance with the federal requirements.

OVCR Research Infrastructure Research Compliance Research Development

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Office of the Vice Chancellor for Research

Office of Research Services (ORS) – search for director in process Office for the Protection of Research Subjects (OPRS) – Jim Fischer Office of Animal Care & Institutional Biosafety (OACIB) – Mary

Bowman Conflict of Commitment & Interest (COCI) – Jacqueline Jancius Clinical Trials Office (CTO) – Assistant Vice Chancellor Lisa Pitler Associate Vice Chancellor/Research Integrity Officer – Mark Grabiner Associate Vice Chancellor for Research – Luisa DiPietro Associate Vice Chancellor for Research – Martha Daviglus IT/Communications – Jacqueline Berger Research Development Services (RDS) – Tony Halford Research Resources Center (RRC) - Bill Hendrickson Biologic Resources Laboratory (BRL) – Jeff Fortman

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Office Connected to but not reporting to OVCR

Office of Technology Management (OTM)‒ since 2004 – reports to OVPR in UA

Grants & Contracts ‒ Reports to OBFS

Research Parks – UIRP LLC – URO‒ reports to a BOM and ultimately to UI BoT; VCRs and VCAS are

voting members

Illinois Ventures LLC – URO‒ reports to a BOM and ultimately to UI BoT; VCR voting member

UILABS Not URO‒ separate Board

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Various Compliance Visits FY13-14

• FDA• OHRP-NIH• ORI• VHA Office of Research Oversight• VHA Data Security and Privacy Oversight• USDA – annual unannounced visit• Office of Laboratory Animal Welfare – NIH• DEA• NIH- Biosafety• AAALAC• DOD• BARDA• AAHRPP• NSF• HRSA • ONR• Help with A-133annual audit

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Office of the Vice Chancellor for Research

Partner with UIUC and UIS to develop and launch a new electronic research administration (ERA) tool

– START myResearch (http://web.uillinois.edu/start_myresearch) (Systemwide Tools for Administration of Research and Training)

‒ PI Portal launched‒ Kuali Coeus – open source software being used for

development of the new ERA‒ Pre-award module being developed‒ IRB and IACUC modules being determined

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Rankings

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Comparison of NSF Total R&D Expenditures Ranking Amongst Comparable Institutions FY1992-2012

UIC

UC Irvine

SUNY Buffalo

Cincinnati

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Rankings

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Comparison of NSF Total R&D Expenditures Ranking Amongst Illinois Institutions FY1992-2012

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UIUC

Northwestern

U of Chicago

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Research Development Services

Searchable databases Limited Submissions Internal Funding

Internal Funding Opportunities OVCR Pilot Grants

– Develop new pilot data OVCR Pilot Grants for Architecture, Arts, and Humanities

– Jumpstart new architectural, artistic, or humanities scholarship Chancellor’s Discovery Fund for Multidisciplinary Research

– Initiate multidisciplinary research Ignite Proposal Development Program

– Craft a major external proposal Bridge Funding Program

– Bridge gaps between grants

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Office of Research Services

The Office of Research Services (ORS) is the central University office responsible for all pre-award and non-financial post-award sponsored project activities for the Chicago, Rockford and Peoria campuses of the University of Illinois.

RDS and ORS supports faculty from development to award stage.

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ORS Authority

ORS is the authorized institutional representative for sponsored project activity and provides institutional endorsements on proposal submissions.

ORS has delegated Board of Trustees signature authority to bind the university on sponsored research agreements and award acceptance.

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Goal of the UIC Human Subjects Protection Program

To ensure a comprehensive Human Subjects Protections Program (HSPP): – Utilizing the highest ethical and professional standards – Affording the highest possible protections for our human subjects – Minimize risk to subjects; and– Maximize benefits of the research.

Human Subjects

– living individual(s) about whom an investigator (whether professional or student) conducting research obtains:

(1) data through intervention or interaction with the individual, or

(2) identifiable private information.

45CFR46.102(f)

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Office for Animal Care and Institutional Biosafety

Adminitrative support for the review and approval of research protocols (experiments) involving animals, recombinant and synthetic DNA and infectious agents, and ensures compliance with regulations related to the use of controlled substances in animal research.

Regulatory issues to ensure compliance with the regulations for the protection and welfare of animals, protection and safety of investigators, and the Regulations Pertaining to Research

Animals rDNA Infectious Agents Toxins- Biological Controlled Substances Select Agents Humans Chemicals Radionucleotides X-rays/Irradiators Lasers Embryonic Stem Cells Conflict of Time/Commitment Conflict of Interest Import/Export Material Transfer

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Sponsors and Activities

Sponsors may include, federal, state, municipalities, foundations, private sector (e.g. associations, international, bio-medical, pharmaceuticals).

Types of activities may include: Research, Instruction, Public Service, Technical Testing, Clinical Trials, SBIR/STTRs, Data Use Agreements, Non-Disclosure and Confidentiality Agreements, Collaborative Agreements, Material Transfer Agreements.

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Conflict of Interest

The Changing Environment– Federal regulations– University Policy

Main Points– COI Defined– COI and RNUA– Reporting and Managing Conflicts

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What is financial conflict of interest?

“A ‘conflict of interest’ arises when an academic staff member is in a position to influence either directly or indirectly University business, research, or other decisions in ways that could lead to gain for the academic staff member, the staff member's family, or others to the detriment of the University's integrity and its missions of teaching, research, and public service.”

“Family" is defined as one's spouse or domestic partner, parents, siblings and children.

Conflicts reside in a situation, and do not imply improper behavior.

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Research Integrity at UIC

Goal:– promote compliance with the highest scholarly standards

Purpose:– provide impartial fact-finding and fair adjudication of allegations

research misconduct

Policy:– UI Policy and Procedures on Integrity in Research and

Publication http://research.uic.edu/node/1437/policies/policies – PHS Policies on Research Misconduct

42 CFR 50 and 93 (rev. 2005) http://ori.hhs.gov/sites/default/files/42_cfr_parts_50_and_93_2005.pdf

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Research Resources Center

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Research Resources Center

Assures accessibility of shared resources to all researchers in the UIC community

Serves >1,000 investigators, $160M 013 grants $8 M operating budget, 45% subsidy 60 staff; full-time PhD lab directors in each facility Faculty Academic Directors East and West Campus central facilities

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Biologic Resources Laboratory

UIC’s Centralized Animal Research Facility

Oversight of the institution’s animal care and use program– Support research– Daily care and husbandry of all laboratory animals– Procurement of all animals– Ensure animal welfare – Ensure compliance with regulatory agencies– Ensure the health status of animal colonies– Train students, staff, and faculty

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Program Scope

UIC’s Animal Care and Use Program has been continually accredited by AAALAC International since 1970.

137,000 sq. ft. 10 satellite facilities House over 20 species Ave. daily census 32,000 animals

– Mice 30,000

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OVCR Contact Information

Main Phone: 312-996-4995

Main Website: http://research.uic.edu

RDS: http://research.uic.edu/funding ORS: http://research.uic.edu/sponsored_programs OPRS: http://research.uic.edu/compliance/irb OACIB: http://research.uic.edu/compliance/acc COI: http://research.uic.edu/compliance/coi Integrity: http://research.uic.edu/compliance/research-integrity RRC: http://www.rrc.uic.edu

– Phone: 312-996-5600 BRL: http://www.brl.uic.edu/

– Phone: 312-996-7040