1. MEDLINE 2. PUBMED 3. EMBASE 4. Conference Programmes

Search Terms:51 ‘ABCD’ AND ‘TIA’ 34 ‘ABCD2’ AND ‘TIA’ 47‘ABCD AND ‘Stroke’ 29 ‘ABCD2 AND ‘Stroke’

Search Terms:52 ‘ABCD’ AND ‘TIA’ 35 ‘ABCD2’ AND ‘TIA’ 50 ‘ABCD AND ‘Stroke’ 28 ‘ABCD2 AND ‘Stroke’

Search Terms:85 ‘ABCD’ AND ‘TIA’ 117 ‘ABCD2’ AND ‘TIA’ 83 ‘ABCD AND ‘Stroke’ 102 ‘ABCD2 AND ‘Stroke’

2 Excluded (unrelated to topic)

136 Excluded (Duplicate Publications/Not meeting inclusion criteria)

159 Abstracts reviewed

23 studies meeting inclusion criteria

(English 21, Chinese 1, Spanish 1)

163 Abstracts reviewed

2 Excluded (unrelated to topic)

163 Excluded (Duplicate Publications/Not meeting inclusion criteria)

0 Additional studies meeting inclusion criteria

386 Abstracts reviewed

375 Excluded (Duplicate Publication s/Not meeting inclusion criteria)

11 Additional studies meeting Inclusion Criteria

(English 10, Chinese 1)(Full text 4, Conference abstract 7)

93 Abstracts Reviewed

86 Excluded (Duplicate Publication s/Not meeting inclusion criteria)

9 Additional studies meeting inclusion criteria

43 studies identified for analysis and/or author request for data

Figure e-2: Flow diagram of search strategy and results