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1 Immunizations for Children, Adolescents, and Adults MARCH 2015 Immunization Education For Healthcare Providers in Training

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Presented By: Georgia Chapter - American Academy of Pediatrics Georgia Immunization Program In Cooperation with: Georgia Academy of Family Physicians Georgia Chapter American College of Physicians Georgia OB/Gyn Society

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Faculty Disclosure Information In accordance with ACCME* Standards, all faculty members are required to disclose to the program audience any real or apparent conflict of interest to the content of their presentation. This presentation will include the most current ACIP recommendations for frequently used vaccines but is not a comprehensive review of all available vaccines. Some ACIP recommendations for the use of vaccines have not currently been approved by the FDA. Detailed information regarding all ACIP Recommendations is available at www.cdc.gov/vaccines/acip/recs/index.html *Accreditation Council for Continuing Medical Education

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Objectives At the end of this presentation, you will be able to: Recall the role vaccines have played in preventing diseases Discuss the importance of vaccines for children, adolescents and adults Review the most recent CDC recommendations for storage and handling of vaccines List at least 2 reliable sources for immunization information

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INFECTIOUS AGENT PERSON EXPOSED CARRIER DISEASE COMPLETE RECOVERY COMPLICATIONS DEATH RECOVERY WITH SEQUELAE COMPLETE RECOVERY NO DISEASE MAY INFECT UNIMMUNIZED RESULTS OF EXPOSURE TO A VACCINE PREVENTABLE DISEASE

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INFECTIOUS AGENT EXPOSED AND VACCINATED NO DISEASE INDIVIDUAL REMAINS HEALTHY NO TRANSMISSION TO OTHERS NO CARRIER STATE GOALS OF VACCINATING

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Vaccination Terminology (1) Active Immunity Protection produced by the persons own immune system Usually permanent from disease May require multiple doses of a vaccine Passive Immunity Protection transferred from another person or animal Temporary protection that wanes with time Ref: Epidemiology and Prevention of Vaccine-Preventable Diseases. 12th Edition, May 2012

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Vaccination Terminology (2) Antigen A live or inactivated substance (e.g., protein, polysaccharide) capable of producing an immune response Antibody Protein molecules (immunoglobulin) produced by B lymphocytes to help eliminate an antigen Ref: Epidemiology and Prevention of Vaccine-Preventable Diseases. 12th Edition, May 2012

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Vaccines Live, Attenuated Measles,Mumps & Rubella (MMR) Varicella LAIV Rotavirus Herpes Zoster Inactivated Toxoids (DTaP, Td, Tdap) Whole (Hepatitis A, IPV) Split (Influenza - IIV) Recombinant vaccines (Hepatitis B, HPV4, HPV2) Polysaccharide vaccines (PPSV23, MPSV4) Conjugated vaccines (Hib, PCV13, MCV4) Vaccine - A product that interacts with the immune system to produce active immunity against a disease without the risk of the disease and its potential complications. Ref: Epidemiology and Prevention of Vaccine-Preventable Diseases. 12th Edition, May 2012

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Disease Average Annual Reported Cases Pre-vaccine* Cases in U.S. 2013** Provisional Cases in U.S. 2014*** Provisional % Reduction In U.S. 2014 Smallpox48,164Eradicated worldwide in 1980 Diphtheria175,88501>99.9% Measles503,282187628>99.9% Mumps152,2095841,15199.2% Pertussis147,27128,63928,66080.6% Polio (paralytic)16,31610100% Rubella47,74598>99.9% Congenital Rubella Syndrome 82310100% Tetanus1,314262198.4% H. Influenzae Type b Age