1 Decisions, decisions.... 2 dangerous goods -- articles or substances which are capable of posing a risk to health, safety, property or the environment

1Decisions, decisions...Decisions, decisions...

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dangerous goods dangerous goods -- -- articles or substances articles or substances which are capable of posing a risk to health, which are capable of posing a risk to health, safety, property or the environment and which safety, property or the environment and which are shown in the list of dangerous goods are shown in the list of dangerous goods in the IATA Dangerous Goods Regulationsin the IATA Dangerous Goods Regulations

DefinitionsDefinitions

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infectious substanceinfectious substance ---- substances known substances known or reasonably expected to contain or reasonably expected to contain pathogenspathogens pathogenspathogens -- microorganisms -- microorganisms (including bacteria, viruses, (including bacteria, viruses, fungi, parasites, rickettsiae, fungi, parasites, rickettsiae, and prions) which can cause and prions) which can cause disease in humans or animalsdisease in humans or animals


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cultureculture ---- the result the result of a process by which of a process by which pathogens are amplified pathogens are amplified or propagatedor propagated

patient specimenpatient specimen ---- human human or animal material for diagnosis, or animal material for diagnosis, research, treatment, or prevention research, treatment, or prevention purposes (eg, serum, excreta, purposes (eg, serum, excreta, secreta, tissue, body fluids, organs, secreta, tissue, body fluids, organs, parts, and swabs of same).parts, and swabs of same).


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The First Question:The First Question:Is the Substance a Dangerous Good?Is the Substance a Dangerous Good?

Classify the substanceClassify the substance

Regulations Regulations DO NOT applyDO NOT apply

NO YESNO YES

Regulations Regulations applyapply

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Class 1 ExplosivesExplosivesClass 2 GassesGassesClass 3 Flammable LiquidsFlammable LiquidsClass 4 Flammable SolidsFlammable SolidsClass 5 Oxidizing SubstancesOxidizing SubstancesClass 6 Toxic / Infectious SubstancesToxic / Infectious Substances 6.1 Toxic Substances 6.2 Infectious substancesClass 7 Radioactive SubstancesRadioactive SubstancesClass 8 Corrosive SubstancesCorrosive SubstancesClass 9 MiscellaneousMiscellaneous

Our Topic

DOT & IATA Classes of Dangerous GoodsDOT & IATA Classes of Dangerous Goods

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Classification of Infectious SubstancesClassification of Infectious Substances

Category A Substances Category B Substances

Exempt Human / Animal Specimens

Exempt Substances

Biological Products

Patient Specimens

Infectious Substances

Genetically Modified Micro-Organisms and Organisms

Medical or Clinical Wastes

Infected Animals

Patient Specimens

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an infectious substance in a form that, when an infectious substance in a form that, when exposure to it occurs, is capable of causing exposure to it occurs, is capable of causing

permanent disability, life-threatening or fatal permanent disability, life-threatening or fatal disease in healthy humans/animalsdisease in healthy humans/animals assigned to UN 2814 or UN 2900assigned to UN 2814 or UN 2900 follow Packing Instructions 602follow Packing Instructions 602 DOT and IATA include list of Category A DOT and IATA include list of Category A substancessubstances


Category A SubstancesCategory A Substances

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Examples of Category A SubstancesExamples of Category A Substances

virusesviruses -- -- ebola, junin, lassa, machupo,ebola, junin, lassa, machupo, marburg, monkeypox,smallpoxmarburg, monkeypox,smallpox virusesviruses -- -- West Nile, polio, avian West Nile, polio, avian influenza, HIV, hepatitis B, rabies, influenza, HIV, hepatitis B, rabies, Rift Valley feverRift Valley fever bacteriabacteria ---- M. tuberculosisM. tuberculosis RickettsiaRickettsia, , SS dysenteriae 1, dysenteriae 1, VT VT E. coliE. coli, , B anthracisB anthracis,, B abortusB abortus, , B pseudomaleiB pseudomalei, , F tularensisF tularensis, , Y.Y. pestis, pestis,

IN IN ANYANY FORM FORM

CULTURESCULTURESONLYONLY


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an infectious substance which does not meet the an infectious substance which does not meet the criteria for inclusion in Category Acriteria for inclusion in Category A assigned to UN 3373assigned to UN 3373 follow Packing Instructions 650follow Packing Instructions 650

ExamplesExamples - - most clinical microbiology spec & orgsmost clinical microbiology spec & orgs usually pure culturesusually pure cultures specimens for HIV or HCV quantitationspecimens for HIV or HCV quantitation specimen to be cultured for organismsspecimen to be cultured for organisms could be expected to cause infectioncould be expected to cause infection serum tested for Ab to infectious agentsserum tested for Ab to infectious agents


Category B SubstancesCategory B Substances

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Specimens for which there is minimal likelihood that Specimens for which there is minimal likelihood that pathogens are present… professional judgment is pathogens are present… professional judgment is required. required. ExamplesExamples – collected directly collected from humans or animals – collected directly collected from humans or animals for purposes such as research, diagnosis, investigational for purposes such as research, diagnosis, investigational activities, disease treatment and prevention:activities, disease treatment and prevention: biopsies for cancer testingbiopsies for cancer testing excreta, secreta, blood and its components, tissue and tissue excreta, secreta, blood and its components, tissue and tissue

fluid swabs, body partsfluid swabs, body parts serum for non-ID Ab / serology tests serum for non-ID Ab / serology tests blood and urine for chem, glu, hor, PSA, preg, blood and urine for chem, glu, hor, PSA, preg, TDM, organ function tests, drugs, insurance purposesTDM, organ function tests, drugs, insurance purposes

Exempt Human / Animal SpecimensExempt Human / Animal Specimens

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likely to contain or being tested for likely to contain or being tested for pathogen(s) or has reasonable potential to pathogen(s) or has reasonable potential to

cause disease in humans or animalscause disease in humans or animals assigned to UN 3373assigned to UN 3373

Patient SpecimensPatient Specimens



Exempt Human / Animal Exempt Human / Animal SpecimensSpecimens

Must be classified as one of these:Must be classified as one of these: an infectious substance which is transported an infectious substance which is transported

in a form that, when exposure to it occurs, is in a form that, when exposure to it occurs, is capable of causing permanent disability, life-capable of causing permanent disability, life-threatening or fatal disease in otherwise threatening or fatal disease in otherwise healthy humans or animalshealthy humans or animals

assigned to UN 2814 or UN 2900assigned to UN 2814 or UN 2900

minimal likelihood that pathogens are present minimal likelihood that pathogens are present cause.cause.

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Because of the low hazard they present, the following Because of the low hazard they present, the following substances of biological origin are exempted from dangerous substances of biological origin are exempted from dangerous goods requirements and hazardous material regulations.goods requirements and hazardous material regulations. substances which present a “low hazard”substances which present a “low hazard” do not contain infectious substancesdo not contain infectious substances will not cause human / animal diseasewill not cause human / animal disease contain inactivated / neutralized pathogens, no longer pose contain inactivated / neutralized pathogens, no longer pose

a health riska health risk environmental samples (water, soil, food, etc.)environmental samples (water, soil, food, etc.) blood / components for transfusion or transplant blood / components for transfusion or transplant dried blood spots & fecal occult blood specimensdried blood spots & fecal occult blood specimens decontaminated medical wastedecontaminated medical waste


Exempt SubstancesExempt Substances

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derived from living organisms which are manufactured and derived from living organisms which are manufactured and distributed in accordance with the appropriate national distributed in accordance with the appropriate national

authorities, which may have special licensing requirementsauthorities, which may have special licensing requirements used either for prevention, treatment, or diagnosis of used either for prevention, treatment, or diagnosis of disease in humans or animalsdisease in humans or animals for development, experimental or investigational purposes for development, experimental or investigational purposes related theretorelated thereto include, but not limited to finished or unfinished products include, but not limited to finished or unfinished products such as vaccinessuch as vaccines


Biological ProductsBiological Products

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genetic material has been purposely altered through genetic genetic material has been purposely altered through genetic engineering in a way that does not occur engineering in a way that does not occur naturallynaturally

do not meet the definition of an “infectious substance” but are do not meet the definition of an “infectious substance” but are capable of altering animals, capable of altering animals, plants or microbiological plants or microbiological

substances in a way not normally the result of natural substances in a way not normally the result of natural reproductionreproduction assigned to UN 3245assigned to UN 3245 follow Packing Instructions 913follow Packing Instructions 913


Genetically Modified Micro-Organisms Genetically Modified Micro-Organisms and Organismsand Organisms

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wastes derived from the medical treatment of animals or humans or from bio-research medical or clinical wastes containing Category A infectious

substances - assigned to UN 2814 or UN 2900 as appropriate medical or clinical wastes containing Category B infectious

substances, or which are reasonably believed to have a low probability of containing infectious substances – assigned to UN 3291 and follow Packing Instructions 622


Medical or Clinical WastesMedical or Clinical Wastes

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a live animal that has been intentionally infected and is known or suspected to contain an infectious substance transport by air is prohibited unless infectious substance contained can be consigned by any other means may only be transported under terms and conditions approved by the appropriate national authority animal carcasses affected by pathogens of Category A or which would be assigned to Category A in cultures only, must

be assigned to UN 2814 or UN 2900 as appropriate other animal carcasses affected by pathogens included in Category B must be transported in accordance with provisions determined by the competent authority


Infected AnimalsInfected Animals

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Miscellaneous Dangerous GoodsMiscellaneous Dangerous Goods

DRY ICEDRY ICE

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known or suspected Cat B

Category BInfectious Substance

(UN3373)

Classification of Infectious Substance Being Shipped

Patient Specimen(professional judgement should be used; if unable to make professional judgement, consider Category B) for tests not related to an infectious disease or no reason to suspect the specimen is infectious or unlikely to cause disease in humans or animals or does not contain, has minimal liklihood of containing, or is not being tested for pathogens

Exempt Substance

Exempt Human or Animal Specimen

Category AInfectious Substance(UN2814 or UN2900))

Patient Specimen or Culture(professional judgement should be used)

likely to contain or being tested for pathogen(s) or has reasonable potential to cause disease in humans or animals

Biological Substances does not contain infectious substance contains inactivated or neutralized pathogens contains nonpathogenic organisms environmental samples dried blood spots fecal occult blood specimens decontaminated medical waste to be used for transplant or transfusion

known or suspected Cat A or is being tested for Cat A or has characteristics of Cat A or cannot rule out Cat A or uncertain if Cat A or Cat B or is a serious health risk to carrier

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Identification of the SubstanceIdentification of the Substance (Proper Shipping Name) (Proper Shipping Name)

>3,000 dangerous goods 3,000 dangerous goods and and properproper shippingshipping namesnames Only 6 names apply to nly 6 names apply to Classified Substances.Classified Substances. each name… 14 items of info needed 14 items of info needed to identify, pack, ship, to identify, pack, ship, and documentand document

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6 Proper Shipping Names6 Proper Shipping NamesFor Infectious Substances and Dry IceFor Infectious Substances and Dry Ice

CCllaassssiiffiiccaattiioonn UUNN IIDD

NNoo.. PPrrooppeerr SShhiippppiinngg NNaammee

PPaacckk IInnsstt

CCaatteeggoorryy AA 22881144 IInnffeeccttiioouuss SSuubbssttaannccee,, AAffffeeccttiinngg HHuummaannss ((lliiqquuiidd)) 660022 22881144 IInnffeeccttiioouuss SSuubbssttaannccee,, AAffffeeccttiinngg HHuummaannss ((ssoolliidd)) 660022 22990000 IInnffeeccttiioouuss SSuubbssttaannccee,, AAffffeeccttiinngg AAnniimmaallss ((lliiqquuiidd)) 660022 22990000 IInnffeeccttiioouuss SSuubbssttaannccee,, AAffffeeccttiinngg AAnniimmaallss ((ssoolliidd)) 660022 CCaatteeggoorryy BB 33337733 BBiioollooggiiccaall SSuubbssttaannccee,, CCaatteeggoorryy BB 665500 MMiisscceellllaanneeoouuss 11884455 DDrryy IIccee 990044



Dry IceDry Ice

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602 ---- Category A Substance650 ---- Biological Substance, Category B904 ---- Dry IceOther -- Exempt Human & Animal Specimens

Only 4 Packing InstructionsOnly 4 Packing Instructions

These Packing Instructions have been included as These Packing Instructions have been included as separate documents at separate documents at

www.uccs.edu/~pusafety/environmental/index.shtml

Documents

1 Decisions, decisions.... 2 dangerous goods -- articles or substances which are capable of posing a risk to health, safety, property or the environment