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CALIXARENE BASED
CHEMOSENSORS HANNOVER MESSE-2007
16-20 April, 2007
Hannover
Iurii MATVIEIEV
+38 044 551-1628+38 050 501-1393
National Academy of Sciences of Ukraine
Institute of Organic Chemistry Institute of Semiconductor Physics
Institute of Macromolecular Chemistry
Kiev
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Talk outline
1. What is needed in the market?
2. Brief technology description.
3. Stage of development.
4. Who needs it & how many will they need?
5. What is my unique technology advantage?
6. Competitive matrix.
7. How will I beat the competition?
8. Opportunity for joint work.
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Proprietary information statement
• The technology material presented in this talk is available for licensing or joint product development.
• None of the slides contain any confidential or proprietary information which would prevent patenting the technology.
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Problem Description & Market Need(What is the problem? Or, What is needed in the market? And, How big is the potential market? What is the disease
(if it’s a medical talk)? )
• Variety of sensors provide increased efficiency and ecological safety in many industries. Their use is important factor for improvement of the life quality for modern society.
• Application of traditional methods for monitoring of hazardous substances in variable environment (air, water, waste, etc.) is not often effective and has a range of drawbacks, mainly complicity and long-term exposure.
• The main problem in developing of sensor systems is to supply them with the exceptional selectivity towards a different analytes to be detected in environment.
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Brief technology description
• Array of quartz crystal resonators covered with calixarenecontaining receptors which have different sensitivity towards different volatile organic molecules were developed.
• Due to adsorption of analyte molecules onto sensitive surfaces of sensors frequency of quartz resonators is reducing. This frequency shift is considered as a sensor response.
• Obtained array of sensors responses to pulse of analyte vapor is used for “teaching” system and after that – for recognition of chemical image of analyte by means of special mathematical apparatus for statistical treatment (PCA, Neural Network, etc.).
Working cell volume 9 sm3 Number of channel 8; Frequency drift less 0.5 Hz/ 1h Counter range 0 –16 MHz; Resolution 1 Hz; Time single freq. count. 1s; Time of measuring for recognition less 5 min;Number of recognizing chem. images more 10; Range of analyte concentration 10 – 10000 ppm; Working temperature 20 – 30 Software DOS, Win9X; Power supply 12V/0.4A
CALIXARENE BASED CHEMOSENSOR GAZ-1Main technical characteristics
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Advantages(What is my unique and overwhelming technology advantage?)
• Calixarene based Electronic Nose is used for: monitoring of hazardous pollutants in environment; quality control in food industry and agriculture; quality control of perfumes and beverages.
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Experimental results• Kinetic response strongly depends on interaction between
sensitive layer and analyte molecules. Thus, choosing array for given purpose we consider physical-chemical features of sensitive layers.
• Response of several sensors to various analytes
Toluene Benzene n-xylene Chloroform Dichlorethane CH 2 Cl 2 CCl 4
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10
20
30
40
50
60
70
80
90
Res
pons
e (f
reue
ncy
shift
, Hz)
Analyte
Coating type
CA2 CA6 CA7 CA10 CA11 CA12 CA13 CA14
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Stage of development (clinical tests if medical) and international patents
• The series of calixarene based receptors of ions and neutral molecules were synthesized in the Institute of Organic Chemistry NASU (see www.ioch.kiev.ua/calix )
• The sensitive calixarene based polymer films were prepared in the Institute of Macromolecular Chemistry NASU
• The several chemosensor devices were constructed in the Institute of Semiconductor Physics NASU.
STCU project #3643 “Development of chemosensor materials and equipment for detection toxic substances and pollutants in the environment”
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Targeted Market Segment(Who needs it? How many will they need? What
price are they willing to pay, what do they pay now?)
• Food industry and agriculture
• Chemical industry
• Quality control of of perfumes and beverages
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Competition(Who is my competition? How will I beat the competition?)
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Competitive Matrix
Important product or technology characteristics
My company or institute’s product
Name of Competitor #1
Name of Competitor #2,
etc.Key Characteristic
(a)
Key Characteristic (b)
Key Characteristic (c)
Key Characteristic (d) (usually cost)
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Opportunities(What I am seeking. Opportunity for joint work. Seeking potential partners and licensees. And, How much will it
cost?)
We offer the Electronic Nose for:
• Food industry and agriculture
• Chemical industry
• Quality control of perfumes and beverages
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Contact information
Iurii MATVIEIEV
+38 044 551-1628
+38 050 501-1393
National Academy of Sciences of UkraineInstitute of Organic Chemistry
Kiev
