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01. Advanced Fiber type DBMThe trabecular structure of DBM Fiber provides excellent osteoconductive potential
and handling properties.
02. Superior Hemostatic EffectThe BongenerTM carrier acts as a physical barrier providing a platform for clot formation,
which results in excellent bone bleeding control.
03. Superb Graft Containment in Defect Site Due to high viscosity of BongenerTM carrier the DBM product can maintain its
shape and be efficiently contained at the bone defect after its insertion, regardless
of the body fluids of the bone environment.
Compared to the particle type DBM, the fiber network structure of BongenerTM gives excellent
osteoconductive potential by ingrowth of bone formation cells.
Bongener is available in two convenient size syringes and with a Terminal sterilization procedure
utilizing Gamma-Irradiation.
and with a Terminal sterilization procedure
Double-packed by blister packaging
A. Micro CT Findings: The radiopacities (arrows)
indicates new bone formation observed at the
8th post-operative week.
B. Bone Histologic Findings: The osteoblasts
can be observed surrounding the new bone,
while the osteocites are trapped in lacunae
and surrounded by bone matrix. (H & E, x20).
A. Micro CT Findings
DBX Putty DBX Putty
B. Bone Histologic Findings
37 Distilledwater for
60 Minutes
Property Low viscosity
Subject to Mixing, Molding, Injection
High viscosity
Resistant to Irrigation & SuctionHandling
Room Temp ( ) In Body ( )
Confirmed Osteoinductivity in-vivoOsteoinductivity confirmed after 8 weeks of follow up in abdominal muscle pouch of
an anthymic nude rat.
Bongener thickens at body temperature and resists irrigation and remains contained at the surgical site.
Daewoong Pharmaceutical Bldg., Samseong 1-dong, Gangnam-gu, Seoul, KoreaTel : +82-2-550-8094 / Fax : +82-2-550-8616 / E-mail : [email protected]
Best facilities, best technology to provide “tissue” of high quality
SOPM & Program satisfy criteria established by KFDA/ KATB/ FDA/ EATB
Facilities Equipment
rehtOOIB GC
World-classfacitlities and labs &
water-for-injection (WFI)production facility
Organized andwell equipped
Barcode system
U.S. FDA deretsigeRderetsigeR
Traceability elbaecart yllaitraPtcudorp laniFwaR
Facility 001 ssalC001 ssalC
Microbiology Total 3 times (Pre, post and after sterilization) Once after sterilization
Terminal Sterilization citpesA ro maeB-EnoitaidarrI-ammaG
Experts
Tissue Processing byEATB member
Medical ConsultatonAdvice from medical professional
groups with knowledge &experience in transplantation:
Orthopedics, General, Neurological,Cosmetic Surgery, Dentistry, etc.