What is the WHO classification for non-Hodgkin lymphoma?

10 Precursor B cell neoplasms Peripheral B cell neoplasms Percursor T cell neoplasm Peripheral T cell and NK cell

neoplasm

What is the difference between leukaemia and lymphoma?

1 …

WHO classification for Hodgkin’s lymphoma.

10 Nodular sclerosis Mixed cellularity Lymphocyte rich Lymphocyte depletion Lymphocyte predominance

What type of Hodgkin’s lymphoma is most commonly associated with HIV and EBV?

15 Lymphocyte depletion.

Clinically features of a patient with NHL.

1 Painless, generalised

lymphadenopathy.

You have a patient who has just presented, you think they may have HL, how likely are they to have B symptoms?

20 Commonly just present with painless

lymphadenopathy. Nodular sclerosis and lymphocyte

predominance are usually free of systemic symptoms (usually present stage 1 or 2).

Stages III – IV, or mixed cellularity, or lymphocyte depletion are more likely to have B symptoms.

What proportion of lymphoid neoplasms are from B cells? What are the other cells of origin?

5 80-85% Most of the remainder are T cells, NK

cells are quite rare.

Different types of euthanasia. 1 Active voluntary Non-voluntary Involuntary Passive

Arguments in favour of euthanasia. 1 Autonomy. Dignity. Compassion. Difference between active assistance to die

and allowing a person to die is morally irrelevant.

Already occurring. Palliative care is insufficient. ..

Arguments against euthanasia. 1 Life is sacred. Morale difference between killing and

letting someone die. Slippery slope. Procedural safeguards against abuses are

impossible to forsee. Adequate palliative care services already

exist. …

Describe the process of giving bad news through the use of an acronym.

0 Setting Perception Invitations Knowledge Explore and empathise Strategy and summary

What are we looking for on observation for a haematological examination

10 General appearance

racial origin, pallor, bruising, jaundice, scratch marks

What is the pathophysiology of tumor lysis syndrome?

10 Lysis of tumor cells. Release of intracellular contents. Renal failure, multiple organ failure,

death.

Clinical manifestations of hypercalcaemia.

15 Fatigue, anorexia, constipation,

vomiting Vomiting, confusion, thirst and

polyuria Coma, arrhythmia

Aetiology of hypercalcaemia. 15 Primary hyperparathyroidism Malignancy Drug therapy Tourniquet artefact Sarcoidosis

What is of primary concern here. 10

Outline where the hyoid bone would be.

5

Give me four causes of spleen enlargement.

1 Portal hypertension (cardiac failure?) Lymphoma Anaemia Metabolic

What are the immediate and long term complications of lymphoma treatment?

5 Immediate – nausea, vomiting,

inflmaation and ulceration of mucus membranes, alopecia, pancytopenia

Long term – 2degree malignancies, fertility, thyroid, hepatic or renal function

What variant of Reed-Sternbery cell occurs in Nodular sclerosis Hodgkin’s lymphoma?

50 lacunar