ABSTRACTS ACCEPTED FOR ORAL PRESENTATIONSECAS 2017

1-1 Abstract 15-37TARGETED ABLATION OF ECTOPY-TRIGGERING GANGLIONIC PLEXI SITES ALONE FOR PAROXYSMAL ATRIAL FIBRILLATION Belinda Sandler 1, Sikkel Markus 1, Boon Lim 1, Nick Linton 1, Zachary Whinnett 1, Fu Ng 1, Norman Qureshi 1, Afzal Sohail 1, Kevin Leong 1, Vishal Luther 1, Maria Kim 1, Wyn Davies 1, Michael Koa-Wing 1, Nicholas Peters 1, Prapa Kanagaratnam 1

1 Imperial College London, London, United Kingdom

1-2 Abstract 15-17THE IMPACT OF OBESITY ON ATRIAL FIBRILLATION ABLATION: PATIENT CHARACTERISTICS, LONG-TERM OUTCOMES AND COMPLICATIONSRoger Winkle 1, R. Hardwin Mead 1, Gregory Engel 1, Melissa Kong 1, Fleming William 1, Jonathan Salcedo 1, Rob Patrawala 11 Silicon Valley Cardiology, East Palo Alto, United States

1-3 Abstract 15-11THIRD-GENERATION CRYOBALLOON: IS NEW ALWAYS BETTER?Stefan Hartl 1, Benedikt Bunz 1, Uwe Dorwarth 1, Michael Wankerl 1, Florian Straube 1, Ellen Hoffmann 1

1 Heart Center Munich-Bogenhausen, Munich Municipal Hospital Group, Munich, Germany

1-4 Abstract 15-26INCIDENCE OF CLASSIC ATRIAL FLUTTER IN OUTPATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION AS IDENTIFIED WITH A NEW P-WAVE CENTRIC ECG MONITOR: IMPLICATIONS FOR THE AF ABLATION PROCEDURE PROTOCOL.Robert Rho 1, Susan Blancher 1, Mark Vossler 2, Karrie McLendon 2

1 Virginia Mason Heart Institute, Seattle, United States, 2 Evergreen Medical Center, Kirkland, United States

1-5 Abstract 15-16INCIDENCE OF PULMONARY VEIN STENOSIS AFTER RADIOFREQUENCY CATHETER ABLATION OF ATRIAL FIBRILLATIONCas Teunissen 1, Birgitta Velthuis 2, Rutger Hassink 1, Jeroen van der Heijden 1, Evert-Jan Vonken 2, Nick Clappers 1, Pieter Doevendans 1, Peter Loh 1

1 Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands, 2 Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands

1-6 Abstract 15-31WHAT DO PATIENTS WITH INCIDENT ATRIAL FIBRILLATION AND NO COMORBIDITIES AT THE TIME OF DIAGNOSIS DIE OF? Tommy Andersson 1, Ing-Liss Bryngelsson 2, Anders Magnusson 3, Ole Frøbert 1, Karin Henriksson 4, Edvardsson Nils 5, Dritan Poci 1

1 1Dept of Cardiology, School of Medical Sciences, Örebro University, Örebro, Sweden, 2

Dept of Occupational and Environmental Medicine, School of Medical Sciences, Örebro University, Örebro, Sweden, 3 Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden, 4 4Dept of Medical Science, Uppsala University and AstraZeneca R&D, Mölndal, Mölndal, Sweden, 5 Sahlgrenska Academy at Sahlgrenska University Hospital Göteborg, Göteborg, Sweden

2-1 Abstract 23-10AV NODE ABLATION AND PERMANENT HIS BUNDLE PACINGPugazhendhi Vijayaraman 1, Angela Naperkowski 1, Faiz A Subzposh 1

1 Geisinger Heart Institute, Wilkes Barre, United States

2-2 Abstract 31-11HIS BUNDLE PACING REDUCED MORTALITY / MORBIDITY COMPARED TO RIGHT VENTRICULAR PACING IN PACEMAKER POPULATION: LONG-TERM FOLLOW-UPPugazhendhi Vijayaraman 1, Faiz A Subzposh 1, Angela Naperkowski 1, Gopi Dandamudi 2

1 Geisinger Heart Institute, Wilkes Barre, United States, 2 Indiana University, Indianapolis, United States

2-3 Abstract 23-14RIGHT VENTRICULAR HIGH SEPTAL PACING VS. RIGHT VENTRICULAR APICAL PACING FOLLOWING AV NODE ABLATION: 20 YEARS FOLLOW UPWilliam Eysenck 1, Rick Veasey 1, Angela Gallagher 1, Fadi Jouhra 1, Nik Patel 1, Steve Furniss 1, Neil Sulke 1

1 Cardiology Research Department, Eastbourne Hospital, East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom

2-4 Abstract 24-11THROMBOEMBOLIC EVENTS IN LEFT VENTRICULAR ENDOCARDIAL PACING: LONG-TERM OUTCOMES FROM A MULTICENTRE UK REGISTRYVinit Sawhney 1, Guilia Domenichini 1, Victoria Baker 1, James Gamble 2, Guy Furniss 3, Dimitrios Panagopoulos 3, Niall Campbell 4, Martin Lowe 1, Pier Lambiase 1, Guy Haywood 3, Kim Rajappan 2, Simon Sporton 1, Mark Earley 1, Mehul Dhinoja 1, Ross Hunter 1, Tim Betts 2, Richard Schilling 1

1 Barts Heart Centre, London, United Kingdom, 2 John Radcliffe Hospital, Oxford, United Kingdom, 3 Plymouth Hospital NHS Trust, Plymouth, United Kingdom, 4 University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom

2-5 Abstract 24-12RIGHT VENTRICLE IN CARDIAC RESYNCHRONIZATION THERAPY: THE FORGOTTEN CHAMBER Haitham Badran 1, Mazen Tawfik 1, Osama Diab 1, Ayman Mortada 1, Mohamed Amin 1

1 Ain Shams University, Cairo, Egypt

2-6 Abstract 23-12PREDICTORS OF LONG-TERM RV PACING IN PATIENTS POST TRANSCATHETER AORTIC VALVE REPLACEMENT WITH AN EDWARDS SAPIEN VALVEEsseim Sharma 1, Antony Chu 1

1 Brown University, Providence, United States

3-1 Abstract 14-10PERIPROCEDURAL MANAGEMENT DURING LEFT ATRIAL ABLATION: BRIDGING, UNINTERRUPTED VITAMIN K-ANTAGONISTS OR UNINTERRUPTED NOVEL ANTICOAGULANTS?Maria Brinkmeier-Theofanopoulou 1, Panagiotis Tzamalis 1, Susan Wehrkamp-Richter 1, Andrea Radzewitz 1, Matthias Merkel 1, Gerhard Schymik 1, Claus Schmitt 1, Armin Luik 1

1 Medizinische Klinik IV, Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany

3-2 Abstract 18-26USE OF NOVEL GLOBAL ULTRASOUND IMAGING AND CONTINUOUS DIPOLE DENSITY MAPPING TO GUIDE ABLATION IN MACRO-REENTRANT TACHYCARDIAS Claire Martin 1, Shohreh Honarbakhsh 1, Ailsa McLean 1, Pier Lambiase 1, Richard Schilling 1

1 Barts Heart Centre, London, United Kingdom

3-3 Abstract 18-28ABLATION OF INCESSANT AV JUNCTIONAL TACHYCARDIA IN PATIENTS WITH INAPPROPRIATE TACHYCARDIA SYNDROMEBengt Herweg 1, Sanders Chae 1, Michael Fradley 1

1 University of South Florida Morsani College of Medicine, Tampa, Florida, United States

3-4 Abstract 18-14EMPIRIC VERSUS ENTRAINED CAVOTRICUSPID ISTHMUS LINE ABLATION IN CONGENITAL HEART DISEASE: A SINGLE CENTRE EXPERIENCEVinit Sawhney 1, Alex McLellan 1, Dhanuka Perera 1, Deshveer Babra 1, Dionisio Izquierdo 1, Richard Schilling 1, Pier Lambiase 1, Martin Lowe 1, Vivienne Ezzat 1

1 Barts Heart Centre, London, United Kingdom

3-5 Abstract 14-11INDIVIDUALIZED ABLATION APPROACH FOR LEFT ATRIAL TACHYCARDIA AFTER PREVIOUS CATHETER ABLATION OF ATRIAL FIBRILLATIONArmin Luik 1, Tobias Oesterlein 2, Matthias Merkel 1, Patrick Hoermann 1, Kerstin Schmidt 1, Thomas Schenk 1, Maria Brinkmeier-Theofanopoulou 1, Andrea Radzewitz 1, Gerhard Schymik 1, Claus Schmitt 1

1 Staedtisches Klinikum Karlsruhe, Medizinische Klinik IV, Karlsruhe, Germany, 2 Karlsruhe Institute of Technology, Institute of Biomedical Engineering, Karlsruhe, Germany

3-6 Abstract 12-10A NOVEL ELECTROGRAM CHARACTERISTIC AS THE TARGET FOR ATRIOVENTRICULAR NODAL RE-ENTRANT TACHYCARDIA ABLATION Rahul Jain 1, Benjamin Maatman 2, Mamta Barmeda 3, Thomas Kambur 2, Mark Shen 2,

Jonathan Shirazi 2, John Miller 2

1 Division of Cardiology, Department of Medicine, Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, United States, 2 Indiana University School of Medicine, Indianapolis, United States, 3 Indiana University School of Allied Health Sciences, Indianapolis, United States

4-1 Abstract 19-14NATIONWIDE STUDY OF SUDDEN CARDIAC DEATH CAUSED BY CONGENITAL HEART DISEASE IN PERSONS AGED 0-35 YEARSAlexander Gade Jeppesen 1, Thomas Hadberg Lynge 1, Bo Gregers Winkel 1, Lars Søndergaard 2, Bjarke Risgaard 1, Jacob Tfelt-Hansen 2

1 The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 2 The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet. Department of Medicine and Surgery, University of Copenhagen, Copenhagen, Denmark

4-2 Abstract 19-24LONG TERM ARRHYTHMIC RISK ASSESSMENT IN BIOPSY-PROVEN MYOCARDITISGaetano Pinnacchio 1, Gemma Pelargonio 1, Maria Lucia Narducci 1, Gianluigi Bencardino 1, Francesco Perna 1, Gianluca Comerci 1, Stefano Bartoletti 2, Maurizio Pieroni 3, Michela Casella 4, Antonio Dello Russo 4, Fulvio Bellocci 1, Filippo Crea 1

1 Catholic University of the Sacred Heart - Cardiology Institute, Rome, Italy, 2 Liverpool Heart And Chest Hospital, , Liverpool, United Kingdom, 3 Ospedale San Donato, Arezzo, Italy, 4 Cardiac Arrhythmia Research Centre, Centro Cardiologico Monzino IRCCS, Milan, Italy

4-3 Abstract 19-12THE RISK OF SUDDEN CARDIAC DEATH AMONG YOUNG PERSONS WITH DIABETES: A 10-YEAR NATIONWIDE COHORT STUDY IN DENMARKJesper Svane 1, Thomas Hadberg Lynge 1, Ulrik Pedersen-Bjergaard 2, Bjarke Risgaard 1, Bo Gregers Winkel 1, Jacob Tfelt-Hansen 1

1 The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 2 Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital Hillerød, Hillerød, Denmark

4-4 Abstract 19-1710-YEAR DEVELOPMENT IN ALL-CAUSE AND CARDIAC MORTALITY IN THE YOUNG: A NATIONWIDE COHORT STUDY IN DENMARKThomas Hadberg Lynge 1, Bjarke Risgaard 1, Mads Wissenberg 2, Bo Gregers Winkel 1, Reza Jabbari 1, Christian Torp-Pedersen 3, Fredrik Folke 2, Stig Haunsø 1, Gunnar Hilmar Gislason 2, Jacob Tfelt-Hansen 1

1 The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 2 Department of Cardiology, Copenhagen University Hospital, Gentofte, Gentofte, Denmark, 3 The Institute of Health, Science and Technology, Aalborg University , Aalborg, Denmark

4-5 Abstract 19-19CLINICAL AND ELECTROCARDIOGRAPHIC FEATURES OF ASYMPTOMATIC YOUNG INDIVIDUALS WITH SHORT QT INTERVALSNabeela Karim 1, Rui Providência 1, Neil Srinivasan 1, MJ Ferreira 2, L Goncalves 3, Pier D Lambiase 1

1 Barts Heart Centre, London, United Kingdom, 2 Hospitais Universidade Coimbra, Coimbra, Portugal, 3 Hospital dos Covoes, Coimbra, Portugal

4-6 Abstract 19-10THE PHENOTYPIC SPECTRUM OF A MUTATION HOTSPOT RESPONSIBLE FOR THE SHORT QT SYNDROMEDan Hu 1, Yang Li 2, Jiancheng Zhang 3, Ryan Pfeiffer 1, Michael H. Gollob 4, Jeff Healey 5, Daniel Toshio Harrell 6, Naomasa Makita 6, Haruhiko Abe 7, Yaxun Sun 8, Jihong Guo 9, Li Zhang 10, Ganxin Yan 10, Douglas Mah 11, Edward P. Walsh 11, Harris B. Leopold 12, Carla Giustetto 13, Fiorenzo Gaita 13, Agnieszka Zienciuk-Krajka 14, Andrea Mazzanti 15, Silvia G. Priori 15, Charles Antzelevitch 10, Hector Barajas-Martinez 1

1 Masonic Medical Research Laboratory, Utica, United States, 2 Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China, 3 Department of Cardiology, Provincial Clinical Medicine College of Fujian Medical University, Fujian, China, 4 Department of Cardiology, Toronto General Hospital, University of Toronto, Toronto, Canada, 5 Population Health Research Institute, McMaster University, Hamilton, Canada, 6 Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 7 Department of Heart Rhythm Management, University of Occupational and Environmental Health, Fukuoka, Japan, 8 Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China, 9 Department of Cardiac Electrophysiology, Division of Cardiology, People’s Hospital, Peking University, Beijing, China, 10 Lankenau Institute for Medical Research and Jefferson Medical College, Philadelphia, United States, 11 Cardiac Electrophysiology Division, Boston Children's Hospital, Harvard Medical School, Boston, United States, 12 Connecticut Children’s Medical Center, University of Connecticut School of Medicine, Hartford, United States, 13 Division of Cardiology, University of Torino, Department of Medical Sciences, "Città della Salute e della Scienza” Hospital, Torino, Italy, 14 Department of Cardiology and Electrotherapy, Medical University of Gdansk, Gdansk, Poland, 15 Molecular Cardiology, IRCCS Salvatore Maugeri Foundation, Pavia, Italy

5-1 Abstract 28-11NEW IMAGING MODALITY TO SUPPORT FOCAL IMPULSE AND ROTOR MAPPING DURING ATRIAL FIBRILLATION ABLATION PROCEDURESChristopher A. B. Kowalewski 1, Junaid A. B. Zaman 1, Tina Baykaner 1, Mahmood Al-Housseini 1, Fatemah Shenasa 1, Mohan Viswanathan 1, Paul J. Wang 1, Sanjiv M. Narayan 1, Sanjiv M. Narayan 1

1 Stanford University, Stanford, United States

5-2 Abstract 28-12RADIATION SPARING BENEFIT OF 3D MAPPING DURING ABLATIONS IN PATIENTS WITH CONGENITAL HEART DISEASE Dylan Timberlake 1, John Clark 1, Chris Anderson 2, David Bradley 3, Jeremy Moore 4, Grace Smith 1, Volkan Tuzcu 5

1 Akron Children's Hospital, Akron, Ohio, United States, 2 Providence Health & Services, Spokane, Washington, United States, 3 C.S. Mott Children's Hosptial, University of Michigan Health System, Ann Arbor, Michigan, United States, 4 Mattel Children's Hospital UCLA, Los Angeles, California, United States, 5 Medipol International Health Center, Istanbul, Turkey

5-3 Abstract 28-14COMPUTATION OF PANORAMIC ELECTROGRAM PHASE TO IDENTIFY EXCITATION PATTERNS DURING ATRIAL FIBRILLATIONTobias Oesterlein 1, Armin Luik 2, Patrick Hörmann 2, Claus Schmitt 2, Olaf Dössel 1

1 Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany, 2 Medizinische Klinik IV, Kardiologie, Angiologie und Internistische Intensivmedizin, Städt. Klinikum Karlsruhe gGmbH, Karlsruhe, Germany

5-4 Abstract 28-15NOVEL MAPPING TECHNIQUE FOR LOCALIZATION OF FOCAL AND REENTRANT ACTIVATION DURING ATRIAL FIBRILLATIONYoshihide Takahashi 1, Syu Yamashita 1, Mayumi Masumura 1, Masahito Suzuki 1, Kento Yabe 1, Yasuhiro Sato 1, Kenzo Hirao 2

1 Disaster Medical Center, Tokyo, Japan, 2 Tokyo Medical and Dental University, Tokyo, Japan

5-5 Abstract 15-14SHORT-TERM SPATIO-TEMPORAL FLUCTUATIONS IN ATRIAL FIBRILLATION SOURCES AND THEIR IMPACT ON OPTIMAL RECORDING DURATIONChristopher A. B. Kowalewski 1, Fatemah Shenasa 1, Junaid Zambian 1, Tina Baykaner 1, Mahmood Al-Housseini 1, David Krummen 2, Johannes Brachmann 3, Mohan Viswanathan 1, Will Sauer 4, John Miller 5, Paul Wang 1, Sanjiv Narayan 1

1 Stanford University, Stanford, United States, 2 University of California, San Diego, United States, 3 Klinikum Coburg, Coburg, Germany, 4 University of Colorado, Denver, United States, 5 Indiana University, Indiana, United States

5-6 Abstract 28-13VISUALIZATION OF THE DYNAMIC 2D RHYTHMVIEW GRAY-SCALE EXCITATION PATTERN IN 3DTobias Oesterlein 1, Armin Luik 2, Patrick Hörmann 2, Claus Schmitt 2, Olaf Dössel 1

1 Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany, 2 Medizinische Klinik IV, Kardiologie, Angiologie und Internistische Intensivmedizin, Städt. Klinikum Karlsruhe gGmbH, Karlsruhe, Germany

6-1 Abstract 18-27PREDICTORS OF AF ABLATION SUCCESS USING CONTACT FORCE: DOES LEFT ATRIAL SIZE MATTER ANYMORE?Roger A Winkle 1, R. Hardwin Mead 1, Gregory Engel 1, Melissa H Kong 1, William Fleming 1, Jonathan Salcedo 1, Rob A Patrawala 1

1 Silicon Valley Cardiology, East Palo Alto, United States

6-2 Abstract 18-24EFFICACY AND SAFETY OF CRYOBALLOON VERSUS RADIOFREQUENCY ABLATION FOR ATRIAL FIBRILLATION: AN UPDATED META-ANALYSIS Marwan Saad 1, April Slee 2, Sanjeev Saksena 2

1 University of Arkansas for Medical Sciences, Little Rock, United States, 2 EP Research Foundation, Warren, United States

6-3 Abstract 18-25SPONTANEOUS PULMONARY VEIN ECTOPY AND RECURRENCE OF ATRIAL FIBRILLATION AFTER PULMONARY VEIN ISOLATIONMoritz Sinner 1, Benjamin Neumann 1, Reza Wakili 1, Stefan Sattler 1, Johannes Siebermair 1, Eva Klocker 1, Stephanie Fichtner 1, Heidi Estner 1, Stefan Kääb 1

1 Department of Cardiology, University Hospital Munich, Munich, Germany

6-4 Abstract 18-18TRACKING THE FASCICLES AND ABLATING: A NOVEL STRATEGY FOR ISOLATING PULMONARY VEINSMark Shen 1, Mamta Barmeda 2, Thomas Kambur 1, Jonathan Shirazi 1, John Miller 1, Rahul Jain 3

1 Indiana University School of Medicine, Indianapolis, United States, 2 Indiana University School of Allied Health Sciences, Indianapolis, United States, 3 Richard L. Roudebush VA Medical Center, Indianapolis, United States

6-5 Abstract 18-20RADIOFREQUENCY PULMONARY VEIN ISOLATION FOR PAROXYSMAL ATRIAL FIBRILLATION – 14 YEARS OF CONTINUOUS EVOLUTIONPhilippe Purnode 1, Olivier Deceuninck 1, Olivier Xhaët 1, Luc De Roy 1, Fabien Dormal 1, Dominique Blommaert 1

1 CHU UCL Namur - Site Godinne, Yvoir, Belgium

6-6 Abstract 18-21ADENOSINE-PROVOKED DORMANT PULMONARY VEIN CONDUCTION IS ASSOCIATED WITH RECONNECTION SITE IN FOLLOW UP Lisette Wintgens 1, Sevasti-Maria Chaldoupi 1, Martijn Klaver 1, Vincent van Dijk 1, Maurits Wijffels 1, Lucas Boersma 1, Jippe Balt 1

1 St. Antonius Hospital, Nieuwegein, Netherlands

7-1 Abstract 24-19EARLY UPGRADE FROM CRT-D TO MPP IMPROVES THE MYOCARDIAL AND PERIPHERAL VASCULAR REMODELING IN PRIMARY DILATED CARDIOMYOPATHYAmbrogio Capria 1, Luca Santini 2, Silvia Ventresca 3, Germana Panattoni 3, Valentina Ribatti 3, Domenico Giovanni Della Rocca 3, Giovanni Battista Forleo 4, Giulia Magliano 3, Fortunata Condemi 3, Domenico Sergi 3, Francesco Romeo 3

1 University Hospital of Tor Vergata, Department of Internal Medicine, Rome, Italy, Rome, Italy, 2 Ospedale G. B. Grassi - Department of Cardiology, Ostia (Rome), Italy, Rome, Italy, 3 University Hospital of Tor Vergata, Department of Cardiology, Rome, Italy, Rome, Italy, 4 Ospedale L. Sacco - Department of Cardiology, Milano, Italy, Rome, Italy

7-2 Abstract 22-10HIS BUNDLE PACING PRESERVES LV FUNCTION DURING LONG-TERM FOLLOW-UPPugazhendhi Vijayaraman 1

1 Geisinger Heart Institute, Wilkes Barre, United States

7-3 Abstract 24-14MINIMALLY INVASIVE THORACOSCOPIC TECHNIQUE FOR LV LEAD IMPLANTATION IN CARDIAC RESYNCHRONIZATION THERAPYMassimiliano Marini 1, Stefano Branzoli 1, Paolo Moggio 1, Alessio Coser 1, Fabrizio Guarracini 1, Silvia Quintarelli 1, Carlo Pederzolli 1, Angelo Graffigna 1, Roberto Bonmassari 1, Maria Caterina Bottoli 2, Andrea Droghetti 2

1 Ospedale Santa Chiara, Trento, Italy, 2 Ospedale Carlo Poma, Mantova, Italy

7-4 Abstract 23-13PREDICTORS OF LONG-TERM RV PACING IN PATIENTS POST TRANSCATHETER AORTIC VALVE REPLACEMENT Esseim Sharma 1, Antony Chu 1

1 Brown University, Providence, United States

7-5 Abstract 23-15EFFICACY AND SAFETY OF COMBINED AEROBIC, STRENGHT AND FLEXIBILITY EXERCISE TRAINING PROGRAMS IN PATIENTS WITH IMLANTABLE CARDIAC DEVICESMaria Rosaria Squeo 1, Barbara Di Giacinto 1, Massimo Santini 2, Maria Luisa Sette 1, Emanule Fabrizi 1, Attilio Parisi 1, Antonio Spataro 1, Alessandro Biffi 1

1 Institute of Sport Medicine and Science, Rome, Italy, 2 World Society of Arrhythmias, Rome, Italy

7-6 Abstract 24-1510-YEAR FOLLOW-UP IN CARDIAC RESYNCHRONISATION THERAPY: INFLUENCE OF GENDER AND ETIOLOGY ON THE OUTCOME. Giuseppina Belotti 1, Chiara Parmigiani 1, Maria Elisabetta Bellebono 1, Paola Negrini 1

1 Ospedale di Treviglio, Treviglio, Italy

8-1 Abstract 07-19PREDICTING RISK OF SUSTAINED VENTRICULAR ARRHYTHMIA IN ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY: A META-ANALYSISLaurens Bosman 1, Arjan Sammani 1, Folkert Asselbergs 1, Anneline te Riele 1

1 UMC Utrecht, Utrecht, Netherlands

8-2 Abstract 01-15ATRIAL DYSPLASIA AS A NEW MECHANISM FOR ATRIAL FIBRILLATIONArdan M Saguner 1, Deniz Akdis 1, Corinna Brunckhorst 1, Peter K Bode 2, Firat Duru 1, Li Guoliang 3, Guy H Fontaine 4

1 University Heart Center Zurich, Zurich, Switzerland, 2 Institute of Pathology, University

Hospital Zurich, Zurich, Switzerland, 3 The First hospital, Xi'an Jiaotong University and College of Medicine, Xian, China, 4 Hopital Pitie La Salpetriere, Paris, France

8-3 Abstract 01-28DISCORDANCE OF ACTIVATION-RECOVERY INTERVAL RESTITUTION CURVES OBTAINED DURING PHYSIOLOGICAL HEART RATE VARIATION VERSUS EXTRASTIMULUS PACINGFu Siong Ng 1, Kevin MW Leong 1, Lina Kanapakaite 1, Andrea Saglietto 1, Caroline H Roney 1, Norman A Qureshi 1, Phang Boon Lim 1, Sian Harding 1, Wyn Davies 1, Nicholas S Peters 1, Amanda Varnava 1, Prapa Kanagaratnam 1

1 Imperial College London, London, United Kingdom

8-4 Abstract 02-11CORRELATIONS BETWEEN ELECTROGRAM MORPHOLOGY AND CELLULAR COMPONENT OF SCAR ARE LOST WHEN OCCURRING IN COMBINATION WITH FUNCTIONAL MODULATIONSKonstantinos N. Tzortzis 1, Kai Y.K. Wang 1, Chris D. Cantwell 1, Spencer J. Sherwin 1, Rasheda A. Chowdhury 1, Nicholas S. Peters 1

1 Imperial College London, London, United Kingdom

8-5 Abstract 30-10A DEVELOPMENTALLY INSPIRED APPROACH FOR GENERATION OF BIOLOGICAL PACEMAKERS APPLYING AUTOLOGOUS UNMODIFIED ADULT STEM CELLSTahereh Karimi 1, Eckhard Alt 1, Robert Schwartz 2, Jose Islas 2, Vladimir Potaman 2

1 Tulane University, New Orleans, United States, 2 Texas Heart Institute, Houston, United States

8-6 Abstract 01-27FINDINGS IN ENDOMYOCARDIAL BIOPSIES OF PATIENTS WITH TACHYCARDIA-INDUCED CARDIOMYOPATHYDavid Heinzmann 1, Karin Müller 1, Karin Klingel 2, Petra Fallier-Becker 2, Reinhard Kandolf 2, Britta Walker-Allgaier 1, Oliver Borst 1, Jörg Kumbrinck 3, Thomas Kirchner 3, Harald Langer 1, Tobias Geisler 1, Antonios Kilias 1, Jürgen Schreieck 1, Michael Gramlich 1, Meinrad Gawaz 1, Peter Seizer 1

1 Innere Medizin III, Universitätsklinikum Tübingen, University of Tübingen, Tübingen, Germany, 2 Abteilung für Molekulare Pathologie, Universitätsklinikum der Eberhard-Karls-Universität Tübingen, Tübingen, Germany, 3 Institute of Pathology, University of Munich, Munich, Germany

9-1 Abstract 02-10PLAKOPHILIN-2 IS REQUIRED FOR EXPRESSION OF A TRANSCRIPTIONAL NETWORK THAT CONTROLS CALCIUM CYCLING: A NOVEL ARRHYTHMIA MECHANISM IN ARRHYTHMOGENIC CARDIOMYOPATHY.Marina Cerrone 1, Jerome Montnach 1, Xianming Lin 1, Mingliang Zhang 1, Kabir Malkani 1, Esperanza Agullo-Pascual 1, Alejandra Leo-Macias 1, Chantal Van Opbergen 2, David Tester 3, Michael Ackerman 3, Antoon van Veen 2, Hector Valdivia 4, Mario Delmar 1

1 Leon H. Charney Division of Cardiology, NYU School of Medicine, New York, United

States, 2 Dept of Medical Physiology University Medical Centre, Utrecht, Netherlands, 3 Mayo Clinic Windland Smith Rice Sudden Death Genomics Laboratory, , Rochester, United States, 4 Center for Arrhythmias Research, Division of Cardiology, University of Michigan, Ann Arbor, United States

9-2 Abstract 02-13DESMOPLAKIN KNOCK-DOWNS IN ZEBRAFISH RECAPITULATE ARRHYTHMOGENIC CARDIOMYOPATHY TYPE 8 AND INVOLVE WNT/BETA-CATENIN SIGNALING IN AC8 PATHOGENESISGiorgia Beffagna 1, Alice Giuliodori 2, Francesco Vanzi 3, Kalliopi Pilichou 1, Francesco Argenton 1, Cristina Basso 1, Gaetano Thiene 1, Natascia Tiso 2

1 University of Padua, Department of Cardiac, Thoracic and Vascular Sciences, Padua, Italy, 2 University of Padua, Department of Biology, Padua, Italy, 3 University of Florence, Department of Biology, Florence, Italy

9-3 Abstract 01-18GLOBAL HIGH DENSITY MAPPING OF RE-ENTRY VULNERABILITY INDEX IDENTIFIES SITES OF RIGHT VENTRICULAR ARRHYTHMIA INITIATION IN BRUGADA SYNDROME AND ARVC Claire Martin 1, Michele Orini 2, Neil Srinivasan 2, Justine Bhar-Amato 2, Anthony Chow 1, Martin Lowe 1, Ron SImon 1, Peter Taggart 2, Pier Lambiase 2

1 Barts Heart Centre, London, United Kingdom, 2 University College London, London, United Kingdom

9-4 Abstract 03-14SMALL SEQUENCING PANELS VS LARGE SCALE CARDIOMYOPATHY PANELS IN GENETIC TESTING FOR ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY (ARVC)Brittney Murray 1, Cynthia James 1, Crystal Tichnell 1, Hugh Calkins 1, Daniel Judge 1

1 Johns Hopkins University, Baltimore, United States

9-5 Abstract 07-18REGIONAL STRAIN ASSESSMENT DETECTS ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY PRIOR TO OVERT DISEASE EXPRESSION: A MULTISOFTWARE FEATURE TRACKING CARDIAC MAGNETIC RESONANCE COMPARISON STUDYMimount Bourfiss 1, Davis M. Vigneault 1, Brittney Murray 2, Cynthia A. James 2, Crystal Tichnell 2, Firdaus A. Mohamed Hoesein 3, Stefan L. Zimmerman 4, Hugh Calkins 2, Harikrishna Tandri 2, Birgitta K. Velthuis 3, David A. Bluemke 1, Anneline S.J.M. te Riele 5

1 Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, United States, 2 Department of Medicine, Division of Cardiology, Johns Hopkins Hospital, Baltimore, United States, 3 Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 4 Department of Radiology, Johns Hopkins Hospital, Baltimore, United States, 5 ICIN-Netherlands Heart Institute, Utrecht, Netherlands

9-6 Abstract 18-17LONG-TERM OUTCOMES AFTER CATHETER ABLATION OF VENTRICULAR TACHYCARDIA IN PATIENTS WITH STRUCTURAL HEART DISEASE: A

MULTICENTRE UK STUDYVinit Sawhney 1, Alex Breitenstein 1, Waqas Ullah 1, Shoreh Honarbaksh 1, Rui Providencia 1, Girish Babu 1, Manish Kalla 2, Mark Cassar 2, Sandeep Panikker 3, Andrew Kontogeorgis 3, Ian Temple 4, Mark Hall 4, Stefano Bartoletti 4, Tom Wong 3, Kim Rajappan 2, Anthony Chow 1, Pier Lambiase 1, Mehul Dhinoja 1, Richard Schilling 1, Ross Hunter 1

1 Barts Heart Centre, London, United Kingdom, 2 John Radcliffe Hospital, Oxford, United Kingdom, 3 The Royal Brompton Hospital, London, United Kingdom, 4 Liverpool Heart and Chest Hospital, Liverpool, United Kingdom

10-1 Abstract 01-22PHASE SINGULARITY MAPPING VS WAVEFRONT ACTIVATION OF MICROANATOMIC REENTRANT ATRIAL FIBRILLATION DRIVERS IN HUMAN HEARTS EX-VIVOBrian J Hansen 1, Thomas A Csepe 1, Himanshu Dashora 1, Ning Li 1, Jichao Zhao 2, Ahmet Kilic 1, Peter J Mohler 1, Paul ML Janssen 1, John D Hummel 1, Vadim V Fedorov 11 The Ohio State University, Columbus, United States, 2 The University of Auckland, Auckland, New Zealand

10-2 Abstract 01-10PROPOSED MECHANISM FOR TERMINATION OF ATRIAL FIBRILLATION BY PULMONARY VEIN ABLATION PRIOR TO ISOLATION: ELIMINATING ROTATIONAL DRIVERSRachita Navara 1, George Leef 1, Fatemah Shenasa 1, Christopher Kowalewski 1, Tina Baykaner 1, Junaid Zaman 1, Paul Wang 1, Sanjiv Narayan 1

1 Stanford University Medical Center, Palo Alto, United States

10-3 Abstract 15-39ECTOPY-TRIGGERING GANGLIONATED PLEXI SITES ARE NOT CONFINED TO THE PULMONARY VEIN ANTRABelinda Sandler 1, Nick Linton 1, Michael Koa-Wing 1, Louisa Malcome-Lawes 1, Zachary Whinnett 1, Wyn Davies 1, Boon Lim 1, Nicholas Peters 1, Prapa Kanagaratnam 1

1 Imperial College London, London, United Kingdom

10-4 Abstract 15-441-YEAR-OUTCOME AFTER HIGH-DENSITY- MAPPING GUIDED PULMONARY VEIN ISOLATION FOR AF THERAPYJohannes Siebermair 1, Heidi L. Estner 1, Stefan Sattler 1, Korbinian Lackermair 1, Fabienne Risch 1, Stephanie Fichtner 1, Konstantinos Rizas 1, Eva Klocker 1, Sebastian Clauss 1, Ina Klier 1, Moritz F. Sinner 1, Stefan Kääb 1, Reza Wakili 1

1 Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany

10-5 Abstract 15-19THE ASSOCIATION BETWEEN LEFT ATRIAL APPENDAGE VOLUME AND PLASMA DOCOSAHEXAENOIC ACID WITH ATRIAL FIBRILLATION RECURRENCE AFTER CATHETER ABLATIONTomoyuki Shiozawa 1, Kazunori Shimada 1, Gaku Sekita 1, Hidemori Hayashi 1, Haruna Tabuchi 1, Seiji Miura 1, Yuko Kawaguchi 1, Masataka Sumiyoshi 2, Yuji Nakazato 3,

Hiroyuki Daida 1

1 Juntendo University Graduate School of Medicine, Tokyo, Japan, 2 Juntendo University Nerima Hospital, Tokyo, Japan, 3 Juntendo University Urayasu Hospital, Chiba, Japan

10-6 Abstract 01-17TERMINATION OF ATRIAL FIBRILLATION AT A RIGHT ATRIAL ROTOR DURING PROCEDURES SEPARATED BY OVER A YEAR Fatemah Shenasa 1, George Leef 1, Fernando Cruz 1, Naadia Amoako 1, David Ho 1, Chad Brodt 1, Mohan N. Viswanathan 1, Sanjiv M. Narayan 1

1 Stanford University, Stanford, United States

11-1 Abstract 15-13CRYOBALLOON ABLATION OF PULMONARY VEINS: GANGLIONIC PLEXI MODIFICATION AND AF RECURRENCEPugazhendhi Vijayaraman 1, Sarah Worsnick 1, Faiz A Subzposh 1, Angela Naperkowski 1

1 Geisinger Heart Institute, Wilkes Barre, United States

11-2 Abstract 15-38COMBINED ET-GP AND AVN-GP ABLATION WITHOUT PULMONARY VEIN ISOLATION AS A TREATMENT FOR PAROXYSMAL ATRIAL FIBRILLATIONBelinda Sandler 1, Sikkel Markus 1, Boon Lim 1, Louisa Malcome-Lawes 1, Afzal Sohail 1, Vishal Luther 1, Kevin Leong 1, Zachary Whinnett 1, Norman Qureshi 1, Nick Linton 1, Maria Kim 1, Wyn Davies 1, Michael Koa-Wing 1, Nicholas Peters 1, Prapa Kanagaratnam 1

1 Imperial College London, London, United Kingdom

11-3 Abstract 15-36GENERATION OF THE FIRST FUNCTIONAL MAP OF LEFT ATRIAL GANGLIONATED PLEXUS SITES THAT INDUCE AV NODAL BRADYCARDIAMin-Young Kim 1, Markus Sikkel 1, Ross Hunter 2, Guy Haywood 3, David Tomlinson 3, Guy Furniss 3, Muzahir Tayebjee 4, Gordon Begg 4, Chris Cantwell 1, Rheeda Ali 1, Hanney Gonna 1, Belinda Sandler 1, Zhen-Lin Lim 1, Phang-Boon Lim 1, Nicholas Peters 1, Nicholas Linton 1, Prapa Kanagaratnam 1

1 Imperial College London, London, United Kingdom, 2 Barts Heart Centre, London, United Kingdom, 3 Plymouth Hospitals NHS Trust, Plymouth, United Kingdom, 4 Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom

11-4 Abstract 15-45ROBOTIC ABLATION OF ATRIAL FIBRILLATION: IMPACT OF LESION EFFICACY AND BIOMARKERS ON RECURRENCESGaetano Pinnacchio 1, Maria Lucia Narducci 1, Gemma Pelargonio 1, Francesco Perna 1, Gianluigi Bencardino 1, Francesco Cavaliere 1, Massimo Massetti 2, Filippo Crea 1

1 Catholic University of the Sacred Heart - Cardiology Institute, Rome, Italy, 2 Catholic University of the Sacred Heart - Cardiothoracic Surgery Institute, Rome, Italy

11-5 Abstract 01-25THE HAEMODYNAMIC EFFECTS OF THE ROX COUPLER MAY IMPROVE OUTCOMES IN AF PATIENTSWilliam Eysenck 1, Jet van Zalen 1, Guy Lloyd 2, Andrew Marshall 1, Ragu Shunmugam 1,

Steve Furniss 1, Neil Sulke 1

1 Cardiology Research Department, Eastbourne Hospital, East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom, 2 St Bartholomew's Hospital, Barts Heart Centre, London, United Kingdom

11-6 Abstract 18-22GREEN ABLATION: ZERO X-RAY EXPOSURE DURING ABLATION OF PAROXYSMAL ATRIAL FIBRILLATIONzhang jian qiang 1

1 beijing 721 hospital, bei jing, China

12-1 Abstract 01-26VERY-LOW-DENSITY LIPOPROTEIN OF METABOLIC SYNDROME MODULATES GAP JUNCTION AND SLOWS CARDIAC CONDUCTIONHsiang-Chun Lee 1, Chih-Chieh Chen 2, Wei-Chun Tsai 1, Chih-Sheng Chu 1, Ye-Hsu Lu 1, Hsin-Ting Lin 1, Yi-Lin Hsiao 1, Liang-Yin Ke 1, Sheng-Hsiung Sheu 1, Bin-Nan Wu 1, Chu-Huang Chen 1, Wen-Ter Lai 1

1 Kaohsiung Medical University, Kaohsiung, Taiwan, 2 National Sun Yat-sen University, Kaohsiung, Taiwan

12-2 Abstract 03-12REDUCTION OF PRRX1 PREVENTS DEVELOPMENT OF ATRIAL FIBRILLATIONSebastian Clauss 1, Elena Dolmatova 2, Alan Hanley 2, Ling Xiao 2, David Milan 2, Patrick Ellinor 2

1 Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany, 2 Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, United States

12-3 Abstract 03-13KNOCKOUT OF ADAM15 IN MICE RESULTS IN ATRIAL FIBRILLATIONSebastian Clauss 1, Hanley Alan 2, Ling Xiao 2, Julie Mina 2, David Milan 2, Patrick Ellinor 2

1 Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany, 2 Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, United States

12-4 Abstract 01-12IMPACT OF ISCHEMIC AND VALVULAR HEART DISEASE ON ATRIAL EXCITATION: A HIGH-RESOLUTION EPICARDIAL MAPPING STUDYElisabeth M.J.P. Mouws 1, Eva A.H. Lanters 1, Christophe P. Teuwen 1, Lisette J.M.E. van der Does 1, Charles Kik 1, Paul Knops 1, Ameeta Yaksh 1, Jos A. Bekkers 1, Ad J.J.C. Bogers 1, Natasja M.S. de Groot 1

1 Erasmus Medical Center, Rotterdam, Netherlands

12-5 Abstract 15-12RELAXIN SUPPRESSES AF IN AGED HEARTS THROUGH GENOMIC REMODELING.

Guy Salama 1, Brian Martin 1, Guillermo Romero 1, Beth Gabris 1, Ansuman Chattopadhyay 1

1 University of Pttsburgh, Pittsburgh, United States

12-6 Abstract 03-15MOLECULAR EXPLORATION OF STRUCTURAL GENES IN ATRIAL FIBRILLATIONRosa Doñate Puertas 1, Gilles Millat 2, Isabelle Ernens 3, Philippe Chevalier 4

1 Institut NeuroMyoGene, Lyon, France, 2 NGS Sequencing Platform for Molecular Diagnosis, Lyon, France, 3 Luxembourg Institute of Health, Luxembourg, Luxembourg, 4 Louis Pradel Cardiology Hospital, Lyon, France

13-1 Abstract 04-10LEFT VENTRICULAR MYOCARDIAL INNERVATION ASSESSED BY 123I-MIBG SPECT/CT IS A STRONG PREDICTOR OF CARDIOVASCULAR EVENTS IN PATIENTS WITH INHERITED ARRHYTHMIA SYNDROMESJohannes Siebermair 1, Sebastian Lehner 2, Stefan Sattler 1, Konstantinos Rizas 1, Britt-Maria Beckmann 1, Alexander Becker 3, Julia Schiller 1, Corona Metz 1, Matthias Zacherl 2, Nadine Vonderlin 1, Stefan Kääb 1, Marcus Hacker 4, Andrei Todica 2, Reza Wakili 1

1 Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany, 2 Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany, 3 Kardiologische Praxis Weilheim, Weilheim, Germany, 4 Division of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University Vienna, Vienna, Austria

13-2 Abstract 05-17IDENTIFICATION OF SPECIFIC CELLULAR ABNORMALITIES FROM ELECTROGRAM MORPHOLOGY USING SUPERVISED MACHINE LEARNINGKonstantinos N. Tzortzis 1, Kai Y.K. Wang 1, Rasheda A. Chowdhury 1, Spencer J. Sherwin 1, Chris D. Cantwell 1, Nicholas S. Peters 1

1 Imperial College London, London, United Kingdom

13-3 Abstract 07-14HEART FAILURE PROGRESSION AND SURVIVAL IN ATRIAL FIBRILLATION PATIENTS WITH PRESERVED OR REDUCED LEFT VENTRICULAR EJECTION FRACTION: INSIGHTS FROM AN AFFIRM SUBSTUDYApril Slee 1, Marwan Saad 2, Sanjeev Saksena 1

1 EP Research Foundation, Warren, United States, 2 University of Arkansas for Medical Sciences, Little Rock, United States

13-4 Abstract 07-17THE VALUE OF THE TPEAK – TEND INTERVAL IN PREDICTING ARRHYTHMIC OR MORTALITY OUTCOMES IN THE GENERAL POPULATION: A META-ANALYSISGary Tse 1, Mengqi Gong 2, Wing Tak Wong 1, Konstantinos Letsas 3, Vassilis Vassiliou 4, Yat Sun Chan 1, Tsz Ling To 1, Bryan P Yan 1, Guangping Li 2, Paula Whittaker 5, Yunlong Xia 6, Gan-Xin Yan 7, Tong Liu 2

1 The Chinese University of Hong Kong, Hong Kong, China, 2 Tianjin Institute of Cardiology, Tianjin , China, 3 “Evangelismos” General Hospital of Athens, Athens, Greece, 4 Royal

Brompton Hospital and Imperial College London, London, United Kingdom, 5 University of Manchester, Manchester, United Kingdom, 6 Beijing Anzhen Hospital, Capital Medical University, Beijing , China, 7 Lankenau Institute for Medical Research and Lankenau Medical Center, Pennsylvania, United States

13-5 Abstract 07-15FAMILY HISTORY OF HEART FAILURE AFTER MYOCARDIAL INFARCTION IS ASSOCIATED WITH AN INCREASED RISK OF HEART FAILURE AFTER FIRST MYOCARDIAL INFARCTION IN THE YOUNG: A DANISH NATIONWIDE COHORT STUDYCharlotte Glinge 1, Louise Oestergaard 2, Reza Jabbari 1, Regitze Skals 3, Camilla H Jespersen 1, Thomas Engstrøm 1, Christian Torp-Pedersen 3, Gunnar Gislason 2, Jacob Tfelt-Hansen 1

1 The Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 2 Department of Cardiology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark, 3 Department of Health, Science and Technology, Aalborg University, Aalborg, Denmark

13-6 Abstract 07-16ATRIAL FIBRILLATION PECULIARITIES DEPENDING ON BODY WEIGHT ADIPOKINES LEVELS Yuliya Shaposhnikova 1

1 Kharkiv national medical university, Kharkiv, Ukraine

14-1 Abstract 05-22HOW GOOD ARE NEW ELRS IN AF MONITORING? THE REMAP-AF TRIALWilliam Eysenck 1, Neil Sulke 1, Ollie Waller 1, Ragu Shunmugam 1, Rick Veasey 1, Steve Furniss 1

1 Cardiology Research Department, Eastbourne Hospital, East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom

14-2 Abstract 15-24BLOOD PRESSURE MEASUREMENT IN ATRIAL FIBRILLATION: IS THERE A NICHE FOR BRACHIAL CUFF AND SUPRASYSTOLIC ALGORITHMS?William Eysenck 1, Vijaya Kanthasamy 1, Nik Patel 1, Rick Veasey 1, Steve Furniss 1, Neil Sulke 1

1 Cardiology Research Department, Eastbourne Hospital, East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom

14-3 Abstract 03-10ASSOCIATION OF PITX2 GENE VARIATION RS2200733 AND DEVELOPMENT OF ATRIAL FIBRILLATIONIrina Rudaka 1, Dmitrijs Rots 1, Arturs Uzars 1, Ļubova Grineviča 2, Linda Piekuse 1, Oskars Kalējs 2

1 Riga Stradiņš University, Riga, Latvia, 2 Pauls Stradins Clinical University Hospital, Riga, Latvia

14-4 Abstract 01-20SOURCES FOR HUMAN PERSISTENT ATRIAL FIBRILLATION-IS ONE MORE IMPORTANT, OR ARE THEY CO-DOMINANT?Fatemah Shenasa 1, Junaid Zaman 1, Tina Baykaner 1, George Leef 1, Christopher Kowalewski 1, Mahmood I. Alhusseini 1, Gabriela Meckler 1, Albert J. Rogers 1, Samir Hossainy 1, Johannes Brachmann 2, John Miller 3, Wouter-Jan Rappel 4, Shirley Park 1, Mohan N. Viswanathan 1, Paul J. Wang 1, Sanjiv M. Narayan 1

1 Stanford University, Stanford, United States, 2 University of Würzburg, Coburg, Germany, 3 Indiana University, Indianapolis, United States, 4 University of California-San Diego, San Diego, United States

14-5 Abstract 15-18LEFT ATRIAL APPENDAGE CLOSURE IN PATIENTS WITH VERY HIGH BLEEDING RISKLisette Wintgens 1, Veronique Vorselaars 1, Arash Alipour 1, Martin Swaans 1, Benno Rensing 1, Marco Post 1, Lucas Boersma 1

1 St. Antonius Hospital, Nieuwegein, Netherlands

14-6 Abstract 15-29CRYOBALLOON ABLATION VERSUS RADIOFREQUENCY ABLATION FOR PERSISTENT ATRIAL FIBRILLATION: A META-ANALYSIS OF AVAILABLE TRIALSRADIOFREQUENCY (RF) ABLATION REPRESENTS THE STANDARD OF CARE FOR PULMONARY VEIN ISOLATION IN PATIENTS WITH DRUG-REFRACTORY PERSISTENAbdul Shokor Parwani 1, Leif-Hendrik Boldt 1, Florian Blaschke 1, Daniela Blaschke 1, Burkert Pieske 1, Wilhelm Haverkamp 1

1 Charité University Berlin, Berlin, Germany