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ISSN : IJCMI Volume 1 • Issue 11 • 1000269 November, 2014 Clinical case blog http://dx.doi.org/10.4172/2376-0249.1000269 International Journal of Clinical & Medical Imaging Title: Epidermoid Cyst Alexander K. C. Leung 1* and Benjamin Barankin 2 1 Clinical Professor of Pediatrics, University of Calgary; Pediatric Consultant, Alberta Children’s Hospital, Canada 2 Medical Director and Founder, Toronto Dermatology Centre, Canada *Corresponding author: Alexander K.C. Leung, MBBS, FRCPC, FRCP(UK&Irel), FRCPCH, FAAP, Clinical Professor of Pediatrics, the University of Calgary, #200, 233 – 16th Avenue NW, Calgary, Alberta, Canada T2M 0H5, Tel: (403) 230-3322; E-mail: aleung@ ucalgary.ca A 56-year-old woman presented with an asymptomatic, slowly growing, dome-shaped mass on the back of four years’ duration. ere was no known history of local trauma or infection. On examination, a firm, nontender, mass was found on the back. e mass was not attached to any underlying structure. An epidermoid cyst is filled with keratin flakes or debris and its wall is composed of keratinized stratified squamous epithelium. Most cases are acquired and secondary to traumatic or iatrogenic implantation of epithelial cells into the dermal or subcutaneous layer or from obstruction of a pilosebaceous unit in the hair follicle. Typically, an epidermoid cyst presents as an asymptomatic, slow-growing, fluctuant to firm, dome-shaped mass that is not attached to the underlying structure. Epidermoid cysts occur mainly on hair-bearing areas. e condition is usually solitary, but uncommonly, can be multiple. Most epidermoid cysts are 1 to 5 cm in diameter and are unilocular. e occurrence is usually sporadic but certain hereditary syndromes such as Gorlin syndrome, Gardner syndrome, and Lowe syndrome have epidermoid cysts as part of their constellation of features. An epidermoid cyst may be cosmetically unsightly and socially embarrassing if it occurs in an exposed area. e cyst may rupture spontaneously or as a result of trauma with release of keratinous material that results in erythema, swelling and pain. ere can be an odor emanating from these cysts. An epidermoid cyst may become secondarily infected which can result in abscess formation. Rarely, squamous cell carcinoma, basal cell carcinoma, Bowen’s disease, melanoma, and mycosis fungoides may develop in an epidermoid cyst. If removal of an epidermoid cyst is desired for cosmetic purposes or complications, complete excision of the cyst contents and cyst wall is the treatment of choice. Incomplete excision may lead to chronic inflammation and recurrence. Intralesional cortisone for inflamed and painful cysts is beneficial to bring down the pain and swelling. Copyright: © 2014 Leung AKC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Page 1: : C International ournal of olume ssue Clinical & Medical ... · An epidermoid cyst is filled with keratin flakes or debris and its wall is composed of keratinized stratified squamous

ISSN : IJCMI

Volume 1 • Issue 11 • 1000269

November, 2014

Clinical case blog

http://dx.doi.org/10.4172/2376-0249.1000269

International Journal of Clinical & Medical Imaging

Title: Epidermoid CystAlexander K. C. Leung1* and Benjamin Barankin2

1Clinical Professor of Pediatrics, University of Calgary; Pediatric Consultant, Alberta Children’s Hospital, Canada2Medical Director and Founder, Toronto Dermatology Centre, Canada

*Corresponding author: Alexander K.C. Leung, MBBS, FRCPC, FRCP(UK&Irel), FRCPCH, FAAP, Clinical Professor of Pediatrics, the University of Calgary, #200, 233 – 16th Avenue NW, Calgary, Alberta, Canada T2M 0H5, Tel: (403) 230-3322; E-mail: [email protected]

A 56-year-old woman presented with an asymptomatic, slowly growing, dome-shaped mass on the back of four years’ duration. There was no known history of local trauma or infection. On examination, a firm, nontender, mass was found on the back. The mass was not attached to any underlying structure.

An epidermoid cyst is filled with keratin flakes or debris and its wall is composed of keratinized stratified squamous epithelium. Most cases are acquired and secondary to traumatic or iatrogenic implantation of epithelial cells into the dermal or subcutaneous layer or from obstruction of a pilosebaceous unit in the hair follicle.

Typically, an epidermoid cyst presents as an asymptomatic, slow-growing, fluctuant to firm, dome-shaped mass that is not attached to the underlying structure. Epidermoid cysts occur mainly on hair-bearing areas.

The condition is usually solitary, but uncommonly, can be multiple. Most epidermoid cysts are 1 to 5 cm in diameter and are unilocular. The occurrence is usually sporadic but certain hereditary syndromes such as Gorlin syndrome, Gardner syndrome, and Lowe syndrome have epidermoid cysts as part of their constellation of features.

An epidermoid cyst may be cosmetically unsightly and socially embarrassing if it occurs in an exposed area. The cyst may rupture spontaneously or as a result of trauma with release of keratinous material that results in erythema, swelling and pain. There can be an odor emanating from these cysts. An epidermoid cyst may become secondarily infected which can result in abscess formation. Rarely, squamous cell carcinoma, basal cell carcinoma, Bowen’s disease, melanoma, and mycosis fungoides may develop in an epidermoid cyst.

If removal of an epidermoid cyst is desired for cosmetic purposes or complications, complete excision of the cyst contents and cyst wall is the treatment of choice. Incomplete excision may lead to chronic inflammation and recurrence. Intralesional cortisone for inflamed and painful cysts is beneficial to bring down the pain and swelling.

Copyright: © 2014 Leung AKC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.