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2013 Pearson Education, Inc. Chapter 22: Microbial Diseases of the Nervous System $10 0 $20 0 $30 0 $40 0 $50 0 $10 0 $ 100 $10 0 $100 $20 0 $20 0 $20 0 $200 $30 0 $30 0 $30 0 $300 $40 0 $40 0 $40 0 $400 $50 0 $50 0 $50 0 $500 The Nervous System Bacterial Diseases Fungal and Protozoan Diseases Prion Diseases Viral Diseases FINAL ROUND

© 2013 Pearson Education, Inc. Chapter 22: Microbial Diseases of the Nervous System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 The Nervous

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© 2013 Pearson Education, Inc.

Chapter 22: Microbial Diseases of the Nervous System

$100

$200

$300

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$500

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The Nervous System

Bacterial Diseases

Fungal and Protozoan Diseases

Prion Diseases

Viral Diseases

FINAL ROUND

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$100 Question

In the brain, cerebrospinal fluid flows through the

a. subdural space.

b. subarachnoid space.

c. arachnoid mater.

d. pia mater.

ANSWER

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$100 Answer

In the brain, cerebrospinal fluid flows through the

a. subdural space.

b. subarachnoid space.

c. arachnoid mater.

d. pia mater.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$200 Question

What is the order of the layer of meninges fromthe innermost to the outermost?

a. arachnoid mater, dura mater, pia mater

b. dura mater, arachnoid mater, pia mater

c. pia mater, dura mater, arachnoid mater

d. pia mater, arachnoid mater, dura mater

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$200 Answer

What is the order of the layer of meninges fromthe innermost to the outermost?

a. arachnoid mater, dura mater, pia mater

b. dura mater, arachnoid mater, pia mater

c. pia mater, dura mater, arachnoid mater

d. pia mater, arachnoid mater, dura mater

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$300 Question

Inflammation of the brain is called

a. meningitis.

b. encephalitis.

c. neuritis.

d. hydrocephalus.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$300 Answer

Inflammation of the brain is called

a. meningitis.

b. encephalitis.

c. neuritis.

d. hydrocephalus.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$400 Question

Drugs can cross the blood–brain barrier ONLY ifthey are

a. large-molecular-weight molecules.

b. small-molecular-weight molecules.

c. water-soluble.

d. lipid-soluble.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$400 Answer

BACK TO GAME

Drugs can cross the blood–brain barrier ONLY ifthey are

a. large-molecular-weight molecules.

b. small-molecular-weight molecules.

c. water-soluble.

d. lipid-soluble.

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$500 Question

Bacteria can grow well in cerebrospinal fluidbecause it has low levels of circulatingantibodies and

a. water.

b. glucose.

c. complement.

d. sodium.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 1: The Nervous System

$500 Answer

BACK TO GAME

Bacteria can grow well in cerebrospinal fluidbecause it has low levels of circulatingantibodies and

a. water.

b. glucose.

c. complement.

d. sodium.

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$100 Question

In adult patients, about 80% of the cases ofbacterial meningitis are now caused byNeisseria meningitidis and

a. Haemophilus influenzae type B.

b. Streptococcus pneumoniae.

c. Listeria monocytogenes.

d. Clostridium tetani.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$100 Answer

In adult patients, about 80% of the cases ofbacterial meningitis are now caused byNeisseria meningitidis and

a. Haemophilus influenzae type B.

b. Streptococcus pneumoniae.

c. Listeria monocytogenes.

d. Clostridium tetani.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$200 Question

The manifestations of tetanus are due to

a. neurotoxin.

b. leukocidins.

c. hemolysins.

d. coagulase.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$200 Answer

The manifestations of tetanus are due to

a. neurotoxin.

b. leukocidins.

c. hemolysins.

d. coagulase.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$300 Question

Which gram-positive rod is known to causestillbirth and neurological disease in animals?

a. Listeria monocytogenes

b. Streptococcus pneumoniae

c. Clostridium botulinum

d. Haemophilus influenzae

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$300 Answer

Which gram-positive rod is known to causestillbirth and neurological disease in animals?

a. Listeria monocytogenes

b. Streptococcus pneumoniae

c. Clostridium botulinum

d. Haemophilus influenzae

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$400 Question

BACK TO GAME

ANSWER

A polysaccharide vaccine that can be muchimproved by conjugation with protein carriersexists against which form of bacterialmeningitis?

a. Haemophilus influenzae

b. pneumococcal

c. meningococcal

d. Listeria monocytogenes

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$400 Answer

BACK TO GAME

A polysaccharide vaccine that can be muchimproved by conjugation with protein carriersexists against which form of bacterialmeningitis?

a. Haemophilus influenzae

b. pneumococcal

c. meningococcal

d. Listeria monocytogenes

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$500 Question

Which of the following statements aboutMycobacterium leprae is FALSE?

a. Patients must be put into isolation.

b. Patients transmit the disease directly.

c. Patients rarely die of the disease.

d. A skin biopsy sample can be used for diagnosis.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 2: Bacterial Diseases

$500 Answer

Which of the following statements aboutMycobacterium leprae is FALSE?

a. Patients must be put into isolation.

b. Patients transmit the disease directly.

c. Patients rarely die of the disease.

d. A skin biopsy sample can be used for diagnosis.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$100 Question

Trypanosoma brucei is transmitted by

a. tsetse flies.

b. body lice.

c. houseflies.

d. head lice.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$100 Answer

Trypanosoma brucei is transmitted by

a. tsetse flies.

b. body lice.

c. houseflies.

d. head lice.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$200 Question

Which etiological agent that causes meningitisproduces an extremely heavy (thick)polysaccharide capsule?

a. Haemophilus influenzae

b. Streptococcus pneumoniae

c. Listeria monocytogenes

d. Cryptococcus neoformans

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$200 Answer

Which etiological agent that causes meningitisproduces an extremely heavy (thick)polysaccharide capsule?

a. Haemophilus influenzae

b. Streptococcus pneumoniae

c. Listeria monocytogenes

d. Cryptococcus neoformans

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$300 Question

Which of the following patients are the mostsusceptible to fungal infections?

a. elderly patients

b. infants

c. immunocompromised patients

d. cardiac patients

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$300 Answer

Which of the following patients are the mostsusceptible to fungal infections?

a. elderly patients

b. infants

c. immunocompromised patients

d. cardiac patients

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$400 Question

Which etiological agent has a mortality rate near100%, with death occurring within a few days,after symptoms appear?

a. Cryptococcus neoformans

b. Acanthamoeba

c. Naegleria fowleri

d. Trypanosoma brucei

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$400 Answer

BACK TO GAME

Which etiological agent has a mortality rate near100%, with death occurring within a few days,after symptoms appear?

a. Cryptococcus neoformans

b. Acanthamoeba

c. Naegleria fowleri

d. Trypanosoma brucei

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$500 Question

Granulomatous amebic encephalitis is caused by

a. Balamuthia mandrillaris.

b. Naegleria fowleri.

c. Trypansoma brucei.

d. Cryptococcus neoformans.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 3: Fungal and Protozoan Diseases

$500 Answer

Granulomatous amebic encephalitis is caused by

a. Balamuthia mandrillaris.

b. Naegleria fowleri.

c. Trypansoma brucei.

d. Cryptococcus neoformans.

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$100 Question

Which of the following diseases is caused by aprion?

a. rabies

b. Creutzfeldt-Jakob disease

c. polio

d. wound botulism

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$100 Answer

Which of the following diseases is caused by aprion?

a. rabies

b. Creutzfeldt-Jakob disease

c. polio

d. wound botulism

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$200 Question

A prion is a(n)

a. abnormally folded protein.

b. protein subunit.

c. form of a bacterium.

d. viral particle.

ANSWER

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$200 Answer

BACK TO GAME

A prion is a(n)

a. abnormally folded protein.

b. protein subunit.

c. form of a bacterium.

d. viral particle.

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$300 Question

Which animal disease is similar to Creutzfeldt-Jacob disease?

a. anthrax

b. sheep scrapie

c. kuru

d. transmissible spongiform encephalopathy

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$300 Answer

Which animal disease is similar to Creutzfeldt-Jacob disease?

a. anthrax

b. sheep scrapie

c. kuru

d. transmissible spongiform encephalopathy

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$400 Question

One hypothesis of the origin of mad cow diseasein cattle is

a. cattle feed contaminated with scrapie.

b. direct contact with animals infected with scrapie.

c. direct contact with other infected species.

d. hormones in cattle feed.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$400 Answer

BACK TO GAME

One hypothesis of the origin of mad cow diseasein cattle is

a. cattle feed contaminated with scrapie.

b. direct contact with animals infected with scrapie.

c. direct contact with other infected species.

d. hormones in cattle feed.

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$500 Question

What conditions does the WHO recommend to sterilizereusable instruments that might have been exposed toprions?

a. strong solution of sulfuric acid with autoclaving at 134°C

b. strong solution of sodium hydroxide with autoclaving at 115°C

c. strong solution of sulfuric acid with extended autoclaving at 115°C

d. strong solution of sodium hydroxide with extended autoclaving at 134°C

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 4: Prion Diseases

$500 Answer

What conditions does the WHO recommend to sterilizereusable instruments that might have been exposed toprions?

a. strong solution of sulfuric acid with autoclaving at 134°C

b. strong solution of sodium hydroxide with autoclaving at 115°C

c. strong solution of sulfuric acid with extended autoclaving at 115°C

d. strong solution of sodium hydroxide with extended autoclaving at 134°C

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$100 Question

Which disease has an incubation period that isusually long enough to allow immunity todevelop from postexposure vaccination?

a. polio

b. rabies

c. Hansen’s disease

d. arboviral encephalitis

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$100 Answer

Which disease has an incubation period that isusually long enough to allow immunity todevelop from postexposure vaccination?

a. polio

b. rabies

c. Hansen’s disease

d. arboviral encephalitis

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$200 Question

A vaccine against which disease occasionallyreverts to a virulent form and causes disease?

a. rabies

b. Japanese encephalitis

c. West Nile encephalitis

d. polio

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$200 Answer

A vaccine against which disease occasionallyreverts to a virulent form and causes disease?

a. rabies

b. Japanese encephalitis

c. West Nile encephalitis

d. polio

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$300 Question

A misdiagnosis of Guillain-Barré syndrome isoften given to patients with

a. arboviral encephalitis.

b. furious rabies.

c. polio.

d. paralytic rabies.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$300 Answer

BACK TO GAME

A misdiagnosis of Guillain-Barré syndrome isoften given to patients with

a. arboviral encephalitis.

b. furious rabies.

c. polio.

d. paralytic rabies.

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$400 Question

Eastern equine encephalitis has a mortality rateof _____ or more.

a. 20%

b. 50%

c. 30%

d. 70%

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$400 Answer

Eastern equine encephalitis has a mortality rateof _____ or more.

a. 20%

b. 50%

c. 30%

d. 70%

BACK TO GAME

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$500 Question

Arboviral encephalitis is usually diagnosed by

a. agglutination tests.

b. ELISA tests.

c. Gram stain.

d. titer.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

Topic 5: Viral Diseases

$500 Answer

Arboviral encephalitis is usually diagnosed by

a. agglutination tests.

b. ELISA tests.

c. Gram stain.

d. titer.

BACK TO GAME

© 2013 Pearson Education, Inc.

FINAL ROUND Question

The tetanus vaccine is a(n)

a. conjugated vaccine.

b. toxoid.

c. attenuated whole-agent vaccine.

d. inactivated whole-agent vaccine.

BACK TO GAME

ANSWER

© 2013 Pearson Education, Inc.

FINAL ROUND Answer

The tetanus vaccine is a(n)

a. conjugated vaccine.

b. toxoid.

c. attenuated whole-agent vaccine.

d. inactivated whole-agent vaccine.

BACK TO GAME