Embed Size (px)
Citation preview
© 2003, Wellsource Inc.
Effect of Ketogenic Diet on Lipid Levels (shown is LDL-C)
In this group of 141 children followed for 6 months, a ketogenic diet adversely affected blood lipid levels:– Cholesterol +58 mg/dL
– LDL chol +50 mg/dL (2 SD)
– HDL chol –7 mg/dL
– Triglycerides +58 mg/dL
99
148
0
50
100
150
Baseline 6 monthslater
LD
L C
hole
ster
ol (
mg/
dL)
JAMA 290:912-20, Aug 20, 2003
© 2003, Wellsource Inc.
Effect of Ketogenic Diet on HDL Cholesterol
HDL cholesterol levels dropped 7 mg/dL
56
49
0
20
40
60
Baseline 6 months later
HD
L C
h ol e
ster
ol (
mg /
d L)
JAMA 290:912-20, Aug 20, 2003
© 2003, Wellsource Inc.
Effect of Ketogenic Diet on Triglyceride Levels
Triglyceride levels rose by 58 mg/dL
96
154
0
50
100
150
Baseline 6 monthslater
Tri
glyc
erid
e (m
g/dL
)
JAMA 290:912-20, Aug 20, 2003
© 2003, Wellsource Inc.
Effect of Ketogenic Diet on LDL Cholesterol Levels
• At baseline, 75% of the children were low risk (LDL <170)
• After 6 months, 53% were high risk (LDL 130+) and only 28% were in the low risk category
75
28
15
53
0
20
40
60
80
Low risk,<170
High risk,200+
Baseline
6 months later
Stu
dy p
o pu l
a tio
n (%
)
JAMA 290:912-20, Aug 20, 2003
© 2003, Wellsource Inc.
Effect of Ketogenic Diet on HDL Cholesterol Levels
• At baseline, 75% of the children were low risk (HDL >45)
• After 6 months, only 51% were low risk and 16% were in the high risk category (HDL <35)
75
51
6 16
0
20
40
60
80
Low risk,<170
High risk,200+
Baseline
6 months later
Stu
dy p
o pu l
a tio
n (%
)
JAMA 290:912-20, Aug 20, 2003
