-19.0 3.9 hypothetical protein LOC554226LOC554226237794_at

-8.3 3.9 neurotrophic tyrosine kinase, receptor, type 3NTRK3206462_s_at

-2.7 3.9 nuclear receptor subfamily 6, group A, member 1NR6A1242724_x_at

-12.9 4.0 C1q and tumor necrosis factor related protein 3C1QTNF3237634_at

-3.6 4.0 Full length insert cDNA YN57B01no information

1556777_a_at

-4.3 4.1 storkhead box 2STOX2231969_at

-4.9 4.2 Transcribed locus, strongly similar to NP_061844.1 G protein-coupled receptor 27;super conserved receptor expressed in brain 1 [Homo sapiens]

no information

227769_at

-2.4 4.8 zinc finger protein 403ZNF403233937_at

-3.0 5.0 four and a half LIM domains 1FHL1201539_s_at

-3.6 5.3 hypothetical protein FLJ23861FLJ238611558595_at

-3.5 5.4 interleukin 1 receptor-like 1IL1RL1234066_at

-2.2 6.0 endothelin receptor type BEDNRB204271_s_at

-5.7 6.1 exostoses (multiple) 1EXT11562863_at

-2.2 6.8 FAT tumor suppressor homolog 4 (Drosophila)FAT4219427_at

-3.2 6.9 CDNA FLJ34880 fis, clone NT2NE2015885no information

1557647_a_at

-2.1 7.0 sorbin and SH3 domain containing 2SORBS2233720_at

-4.5 7.2 solute carrier family 2 (facilitated glucose transporter), member 3

SLC2A3202499_s_at

-2.0 7.5 tissue factor pathway inhibitor 2TFPI2209278_s_at

-2.6 8.6 receptor tyrosine kinase-like orphan receptor 1ROR1231142_at

-13.7 9.1 forkhead box P2FOXP21555516_at

-2.1 9.5 CDNA FLJ36837 fis, clone ASTRO2011422no information

227383_at

-2.8 9.5 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

ADCYAP1R1226690_at

-5.6 10.2 chemokine (C-X-C motif) receptor 4CXCR4217028_at

-2.4 10.5 tissue factor pathway inhibitor 2TFPI2209277_at

-2.2 11.6 WWC family member 3WWC3225273_at

-2.4 12.5 GPI deacylasePGAP1233479_at

-19.3 13.7 sprouty-related, EVH1 domain containing 1SPRED1233465_at

-47.2 26.9 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

ELAVL4234904_x_at

-3.0 35.2 potassium inwardly-rectifying channel, subfamily J, member 2

KCNJ2206765_at

-14.2 48.9 dachshund homolog 2 (Drosophila)DACH2239738_at

CFPAC-1 shPAUF

Panc-1PAUF

Gene TitleGene Symbol

Probe ID

Supplementary Table 1. List of upregulated genes by PAUF *

-3.6 2.5 activating transcription factor 6ATF6241240_at

-4.3 2.5 hypothetical protein FLJ10213FLJ10213219906_at

-9.0 2.6 hydroxysteroid (17-beta) dehydrogenase 12HSD17B121557252_at

-3.0 2.6 chloride intracellular channel 6CLIC6242913_at

-3.6 2.6 no informationno information

234082_at

-3.1 2.6 hypothetical gene CG012CG012215318_at

-3.6 2.6 mucolipin 3MCOLN3220484_at

-8.2 2.6 hypothetical gene supported by BX647608LOC399959233364_s_at

-2.0 2.7 palladin, cytoskeletal associated proteinPALLD200906_s_at

-2.3 2.8 cyclin-dependent kinase 6CDK6224848_at

-2.2 2.8 stearoyl-CoA desaturase 5SCD5224901_at

-3.2 2.8 thymus high mobility group box protein TOXTOX204530_s_at

-3.9 2.9 RAN binding protein 17RANBP17234137_s_at

-3.2 3.0 deiodinase, iodothyronine, type IIDIO2231240_at

-2.2 3.0 WAS/WASL interacting protein family, member 1WIPF1202665_s_at

-2.1 3.1 zinc finger, MYND domain containing 11ZMYND11243054_at

-2.4 3.2 claudin domain containing 1CLDND1239146_at

-31.5 3.2 exostoses (multiple) 1EXT11564378_a_at

-3.1 3.2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

SERPINA1211429_s_at

-2.2 3.2 hypothetical gene supported by BX647608LOC399959232113_at

-2.2 3.2 cyclin-dependent kinase 6CDK6207143_at

-2.1 3.3 WWC family member 3WWC3219520_s_at

-3.7 3.3 formin binding protein 1FNBP1244286_at

-26.8 3.3 DDHD domain containing 1DDHD1231165_at

-2.6 3.3 histone deacetylase 3HDAC3240482_at

-3.9 3.3 Transcribed locusno information

231513_at

-2.0 3.4 lymphocyte antigen 96LY96206584_at

-4.3 3.4 WAS/WASL interacting protein family, member 1WIPF1202664_at

-2.7 3.5 carboxypeptidase MCPM235706_at

-2.9 3.7 SEC24 related gene family, member D (S. cerevisiae)

SEC24D215209_at

-2.2 3.8 phosphodiesterase 4D interacting protein (myomegalin)

PDE4DIP232615_at

-2.7 3.8 mitogen-activated protein kinase kinase kinase 8MAP3K8235421_at

-15.4 3.8 gap junction protein, alpha 10, 59kDaGJA10221415_s_at

-8.1 3.9 carboxypeptidase MCPM206100_at

CFPAC-1

shPAUF

Panc-1PAUF

Gene TitleGene

SymbolProbe ID

Supplementary Table 1 - continued

-2.1 2.1 kelch-like 22 (Drosophila)KLHL22222141_at

-32.6 2.1 Fc receptor-like 5FCRL5224405_at

-7.8 2.1 no informationno information

234704_at

-2.3 2.1 DBF4 homolog B (S. cerevisiae)DBF4B238757_at

-3.0 2.1 no informationno information

208039_at

-7.4 2.1 regulatory factor X, 3 (influences HLA class II expression)

RFX3207234_at

-2.7 2.1 sterile alpha motif domain containing 4ASAMD4A235756_at

-2.3 2.1 ring finger protein 34RNF34236288_at

-3.5 2.1 no informationno information

1558732_at

-2.7 2.2 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

MASP1210680_s_at

-2.6 2.2 suppressor of variegation 4-20 homolog 1 (Drosophila)

SUV420H11565974_at

-2.2 2.2 Full-length cDNA clone CL0BB018ZE07 of Neuroblastoma of Homo sapiens (human)

no information

41856_at

-4.1 2.2 no informationno information

244755_at

-3.2 2.2 oxidized low density lipoprotein (lectin-like) receptor 1

OLR1210004_at

-2.7 2.2 fibronectin type III domain containing 3BFNDC3B1569490_at

-3.3 2.3 RNA binding motif protein 41RBM41243673_at

-3.0 2.3 KIAA1128KIAA11281554131_at

-4.6 2.3 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)

PLRG1238137_at

-2.1 2.3 Homo sapiens, clone IMAGE:2960615, mRNAno information

1569961_at

-3.8 2.3 Transcribed locus, strongly similar to NP_002137.3 homeo box B3;homeo box 2G;homeobox protein Hox-B3 [Homo sapiens]

no information

237189_at

-3.6 2.3 zinc finger protein 545ZNF545235176_at

-8.7 2.3 GRB2-related adaptor proteinGRAP235102_x_at

-3.5 2.3 actin related protein 2/3 complex, subunit 5, 16kDa

ARPC51569325_at

-2.5 2.4 FGFR1 oncogene partner 2FGFR1OP21556282_at

-9.3 2.4 TDP-glucose 4,6-dehydrataseTGDS237346_at

-2.2 2.4 epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)

EGFR211551_at

-3.5 2.4 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

ITGAV232797_at

-3.1 2.4 neuron navigator 1NAV1242986_at

-8.6 2.5 paired box gene 9PAX9231145_at

-4.1 2.5 acyl-CoA synthetase long-chain family member 4ACSL41557419_a_at

CFPAC-1

shPAUF

Panc-1PAUF

Gene TitleGene

SymbolProbe ID

Supplementary Table 1 - continued

-2.9 2.0 CDNA FLJ37243 fis, clone BRAMY2004387no information

228632_at

-2.7 2.0 PRO1496no information

221155_x_at

-2.8 2.0 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor

ICAM1202637_s_at

-3.9 2.0 ATP-binding cassette, sub-family G (WHITE), member 1

ABCG1204567_s_at

-8.9 2.0 hypothetical protein LOC338653LOC3386531562960_at

-2.0 2.0 hypothetical protein LOC647946LOC647946240365_at

-4.5 2.0 CDNA clone IMAGE:5312582no information

1557018_a_at

-2.2 2.1 CDNA clone IMAGE:4841343no information

230672_at

-2.8 2.1 pentraxin-related gene, rapidly induced by IL-1 beta

PTX3206157_at

-2.9 2.1 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

ITGAV241769_at

CFPAC-1

shPAUF

Panc-1PAUF

Gene TitleGene

SymbolProbe ID

Supplementary Table 1 - continued

* List of 96 genes (104 fragments) expressed at levels more than two-fold higher in Panc-1_PAUF than in Panc-1_Mock and more than twofold lower in CFPAC-1_shPAUF than in CFPAC-1_shCtrl.