Tocopherol vs tocopherol Acetate

MATRIX FINE SCIENCES PVT LTD.

Innovate.Science.Life

1

Beauty and The Human Skin

Beauty IS

Skin Deep

3

Understanding the Human SkinStructure

1. Layered

2. Porous

3. Textured

4. Sensitive

5. Elastic

6. Absorbant

4

Understanding the Human Skin

- Genes External Effects

- Exposure to heat/winds

- Nourishment by food

- Cleansing routine

- Cosmetics applied

Sensitive to Inner Built-up

Cosmetics and The Human Skin

Inner Beauty has

a Strong Link to External Applications


Cosmetics are used on skin for (personal care to) :

Cleanse BeautifyMoisturize Soften Treat scars Protect Hide patches Kill germs Freshen Fragrance Polish Glow/ Shine

We generally use …

15 to 20 cosmetics on

daily basis

Some cosmetics 2 to 3 times in a day


What the Outer Skin Needs

• Antioxidants,,,,,,,,,,,,,,,

• Protection ,,,,,,,,,,,,,

• Moisturizing,,,,,,,,,,,,

• Rejuvenation,,,,,,,,,,

Is Available in

Vitamin E

Indian Manufacturer of Natural Mixed Tocopherols


- Operations Began in June 2014

- Research of More than 4 years in High Concentrate Natural Mixed Tocopherol

- Only Company in India to Manufacture Natural Vitamin E of High Concentrates

- Specialized in the Manufacturing ofVitamin E from Soy and Sunflower

Matrix ensues 50 years of Expertise in Chemical Manufacturing

DiverseIntense

Deep

Rich Base of Experience & Expertise in

Manufacturing & Management of Chemical Industry

Diverse

Rich Base of Experience & Expertise in

Manufacturing & Management

Of Chemical Industry

Background

Deep

IntenseDiverse

THE GROUP


Our Beliefs

LIFE

Manufacturers of

SOURCE

NaturalMatrix Vitamin E is: A non-polar, Fat Soluble Antioxidant Part of a Family of Natural Antioxidants known as Mixed Tocopherols.

We Believe in ……..

Natural Antioxidants : Replace Synthetic Antioxidants like TBHQ, BHA, BHT etc. Preserve the flavor, color and freshness of food products

for longer time, preventing oxidation Create better stabilizing agents Promote better heart health, blood characteristics and

cell functioning Give better healing, moisturizing & caring effects to skin Help increase shelf life of the product

The Search…..

Matrix Vitamin E

A Natural Mixed Tocopherolis a family of

4 Tocopherols and 4 Tocotrienols

Benefits

• Unique Biological Effects due to Natural RM Source• Alpa and Gama Tocopherols Combine to give the Most

Effective Results on use

Classified as Alpha, Beta, Gama , Delta Tocopherols

Which are the Hydrocarbon Phytyl side Chains attached

to a Chromanol Head

Tocopherol - Chemistry

Tocopherols function to capture and interrupt free radical chain reactions. This gives them their antioxidant properties.

The free hydroxyl group on the aromatic ring is responsible for the antioxidant properties.

The hydrogen from this group is donated to the free radical, resulting in a relatively stable free radical form of the vitamin.



Antioxidants,,,,,,,,,,,

Protection ,,,,,,,,,,,,,

Moisturizing,,,,,,,,,,,

Rejuvenation,,,,,,,,,,


Vitamin

Function of Vitamin E in Cosmetics

Antioxidant Suppression of pigmentationand bruisingStimulation of collagenSynthesisRefinement of skin surfaceAnti inflammatory effect

Neutralizing free radicals generated by UV light and pollutants

Improving performance of cosmetics

AN EXTREMELY VALUABLE INGREDIENT

Applications of Vitamin E in Cosmetics

under eye gel

oils Creams

Cuticle cream

GelsLipstick

Body scrubs

Anti-wrinkle cream

Anti-scar creams

Anti-pimple cream

Moisturizing creams / Lotions

Skin healing ointments

Soaps

Beauty oils

Natural Vitamin E :

Increases the efficacy

- of active sunscreen ingredients

Prevents the peroxidation of fats,

- a leading source of cell membrane damage

Reduces trans-epidermal water loss- from skin

Strengthens the barrier

- function of the skin

Protects the oil (lipid) balance

- during the cleansing process of the skin barrier

Usage Benefits in Cosmetics

Natural Vitamin E :

Fights Skin Aging : Fights free radicals like sun, pollution and smoke &

helps prevent skin from signs of photo aging - wrinkles , discoloration etc.

Improves Texture of Dry Skin : Being highly absorbant it improves

skin moisture content and hence texture of the dry skin.

Reverses Aging Effects : Eliminates free radicals loosening theconnective tissues under the skin surface , and tightens the skin andreduces wrinkles

Reduces Sun Damage : By better absorption on the surface of theskin and creating a nourishing layer that protects the surface

Controls Acne : Regulates skin elasticity boosting retinol level inhumans. This tightens the skin and reduces inflammation in pores, thuscontrolling acne.

Application Effects on skin

Natural Vitamin E :

Protects against photo oxidative damage to cell membranes

vitamin E plays a prophylactic role against many light-induced diseases

and conditions of the eye (cataract ogenesis and retinal photo

deterioration) and skin (erythrocyte photohemolysis, photo erythema,

photo aging and photo carcinogenesis)

Cleansing agent : Vitamin E is a Universal cleanser, suitable for all skin types, deep cleansing the skin and giving it a radiant glow

Under eye treatment : Vitamin E can be applied around sensitive areas of the eye and as a great moisturiser prevents fine lines – crow feet

Makeup remover : wiping with cotton ball dipped in Vitamin E can remove all traces of makeup

Application Effects on skin

Natural Vitamin E :

Heals Burn Wounds : Due to its curative properties

Treatment of Scars : Swiftly fades scars due to good absorption ability

and penetration in the skin

Treatment of Stretch Marks : The eye and as a great moisturiser

prevents fine lines – crow feet

Treatment of dry nails and cuticles : Helps get rid of brittle, cracking

and splitting nails and cuticles with regular application

Treatment of Chapped lips and soars : Due to the moisturising

properties of Vitamin E

Application Effects on skin Health

Natural Vitamin E :

Stimulates Hair Growth : Antioxidants in vitamin E improve blood

circulation to the scalp and stimulates hair growth

Revents pre-mature greying: Greying of hair is caused by oxidation of

tissues. Antioxidants in Vitamin E prevents the corrosion of tissues, stops

premature greying and aging of hair.

Lustorous hair: Regular oiling and massage with Vitamin E oils/blends can

moisturise hair from roots to shaft , stimulate the production of sebum and

restore shine

Reparis Split Ends : Caused due to continuous blow drying, colouring, curling

Application Effects on Hair

What is Better….

The Natural

Chapter 22, More than Skin Deep :

Papas, A : The Vitamin E Factor

Vitamin E can prevent damage to the

skin from UV rays, pollutants and aging if the

right form is used…( WHICH IS NOT )….

Chapter 22, More than Skin Deep :

Papas, A : The Vitamin E Factor

Alpha-Tocopherol protects the skin againstcancer from exposure to ultra violet (UV) B rays. Incontrast the alpha – tocopherol acetate does notprotect against these cancers. It is, therefore,disturbing that alpha-tocopherol acetate is form ofVitamin E in most of the commercial sunscreensand lotions

Professor Daniel C LeiblerDepartment of Phamacology, University of Arizona

Naturally OccurringNo External Additions

Lipid Soluble, Hence Chances of Contamination with other Ingredients LowHelps Prevent Oxidation and

Rancidity in oil based Formulations

Tampered ( made) in Laboratory

Additions of Acetic Acid and other Chemical based Ingredients

Does not Prevent Rancidity inOil Based Formulations

The Form Makes the Difference.

Natural Mixed Tocopherol - Vitamin Egives the complete advantage

For Good Skin Health

The Natural Vs. Synthetic

No Harmful or Irritating Effects to Skin

Harmful and Irritating to Skin – in Terms of Redness, Rashes, Allergic Reactions, Contamination with Hydroquinone the Whitening Compound can Cause Dermatitis, increased Sensitivity to UV rays and Potential to Develop CarcenogenicProperties





d-alpha TocopherolExtracted from Soyabean OilMore BioavailableHas available –OH hydroxyl group Donating free Proton to Prevent Oxidation

dl-alpha TocopherolExtracted from PetrochemicalsLess potentLacks the free –OH group making it less Antioxidant





Chapter 22, More than Skin Deep :Papas, A : The Vitamin E Factor, Pg.272

Muzzled Vitamin E cannot help on the skin ! Most skinproducts contain the muzzled synthetic dl-alpha- tocopherol.Some contain other esterified forms ofd-alpha-tocopherol acetate or dl-alpha-tocopherol linoleate !Muzzled alpha-tocopherol whether natural or synthetic doesnot help !

Is the muzzle removed when Vitamin E penetrates the skin ?Unfortunately not ! A small, amount of free alpha-tocopherolis released. But the bulk remains muzzled .

That means missing most of the benefit !!

Are made from natural source which protects cell membranes, prevents oxidation and controls degeneration

Due to molecular structure, are well absorbed and hence naturally better utilized by human skin

Are acetate and succinateesters of tocopherol made from acetic acid which is an irritant to the skin

Are less absorbed naturally by the skin and hence not completely utilized by human skin





High biological activity with less quantity application on the skin

More effective since better absorbed by skin tissues

Not toxically harmful to skin, since a natural variant

Needs higher quantity of use to get the biological activity of natural Vitamin E

Less effective, since discarded and not well absorbed by skin tissues

Can result in skin toxicity if built up in the fatty tissues of the skin





Why use Our

Natural Mixed Tocopherols ?

NaturalWe Believe in ……..

Natural Antioxidants :Source : Plant base ( Soy , Sunflower )Green Technology : Molecular Distillation

: Hydrogenation: CO2 extraction

Non Denatured product : Non GMO productProduction of co-products: Bio fuels, not waste Reduced transportability : Reduced carbon costs in RM

sourcing

We Have a Modern Automated Plant

NaturalWe Believe in ……..

Our Products are

Free from

Animal origin

Gluten

Lactose

Alcohol

Certified CERT ID Kosher Halal

Systematic Quality Control

Matrix Vitamin E is a Natural Blend

Of Mixed Tocopherols

Consisting of all 4 Forms of Tocopherols

80 % of these are Gamma – TocopherolsWhich Exhibits

the Highest Antioxidant Properties

Recognized GRAS Generally Recognized as Safe as a nutrient and preservative

Matrix Systems and CertificationsMatrix Fine Sciences Pvt. Ltd is providing Natural

Mixed Tocopherol with below Certifications

KOSHER, HAAL, CERT ID, FSSAI

Pre-registered for Reach

We Will ALSO be Supplying …Organic Squalene to the Cosmetic Industry soon…

A natural 30-carbon organic compound

Found in plants and vegetables

A common lipid produced by the human skin

A natural moisturiser

Low in acute toxicity

Not a human skin irritant or sensitizer

A chemopreventive substance protecting from cancer


Moisturizing Skin care creams and lotions for protection against :

Dry skin

Wrinkle formation

Aging skin

DNA damaged by UV radiation


Squalene as such in softgel capsules, have excellent therapeutic application in :

Psoriasis,

Cholesterol management,

Adjunct in chemotherapy,

Dry skin,

Diabetic wound healing


MATRIX FINE SCIENCES PVT LTD.

Innovate.Science.Life

56

Source Acknowledgement…

Papas A : The Vitamin E Factor : chapter 22 : More than Skin Deep : pg. 263 -277, 1993, Harper Collins

http://www.edenbotanicals.com/vitamin-e-oil.html

http://www.hallstar.com/pis.php?product=1VEN1

http://www.annmariegianni.com/ingredient-watch-list-tocopheryl-acetate-the-potentially-irritating-form-of-vitamin-e

http://www.paulaschoice.com/cosmetic-ingredient-dictionary/definition/vitamin-e

http://www.makingcosmetics.com/

Vitamin E_ MedlinePlus Supplements.html


http://www.annmariegianni.com/ingredient-watch-list-tocopheryl-acetate-the-potentially-irritating-form-of-vitamin-e


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Tocopherol vs tocopherol Acetate