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1) Describe the distinguishing characteristics of the different muscle tissues 2) Discuss the organization of skeletal muscle 3) Explain the micro-anatomy of a skeletal muscle fiber 4) Describe the fascicle arrangement in different types of muscle Skeletal Muscle Tissue and Organization main objectives: www.freelivedoctor.com

Skeletal Muscle Tissue And Organization

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Page 1: Skeletal  Muscle  Tissue And  Organization

1) Describe the distinguishing characteristics of the different muscle tissues

2) Discuss the organization of skeletal muscle

3) Explain the micro-anatomy of a skeletal muscle fiber

4) Describe the fascicle arrangement in different types of muscle

5) Review general muscle terminology

Skeletal Muscle Tissue and Organization

main objectives:

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Page 2: Skeletal  Muscle  Tissue And  Organization

Muscle Muscle tissuetissue vs. Muscle as an vs. Muscle as an organorgan

One of the 4 primary tissue types

How many subtypes?

Made up of _____ tissue types.

> 700 skeletal muscles

Word roots:sarco mys

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Page 3: Skeletal  Muscle  Tissue And  Organization

Function of Skeletal MusclesFunction of Skeletal Muscles

1. Skeletal movement

2. Posture and body position

3. Support of soft tissues

4. Guarding of entrances & exits

5. Maintenance of body temperature

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Page 4: Skeletal  Muscle  Tissue And  Organization

Gross AnatomyGross Anatomy

Each skeletal muscle is wrapped by 3 concentric layers of connective tissue.

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Page 5: Skeletal  Muscle  Tissue And  Organization

Epi-, Peri-, and Endomysium

Are interwoven - Go over into tendon

Distinguish between:TendonAponeurosisLigament

Function: ProtectionBlood supplyInnervation

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Page 6: Skeletal  Muscle  Tissue And  Organization

Nerve and Blood Vessel Supply

Skeletal muscles are rich in nerves and blood vessels

Chemical communication at Synapsis (neuromuscular junction)

Synaptic terminal of axon meets motor end plate of muscle cell

Coiled capillaries are able to adapt to changes in length of muscle fiber

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Page 7: Skeletal  Muscle  Tissue And  Organization

Microanatomy of Skeletal Muscle FibersMicroanatomy of Skeletal Muscle Fibers

Some vocabulary:

Skeletal muscle fiber or myofiber

Sarcolemma

Sarcoplasm

Sarcoplasmic reticulum

Myofibril

Myofilaments

Fig 9-3

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Page 8: Skeletal  Muscle  Tissue And  Organization

Myofiber Myofiber (( 100µm) 100µm) Myofibrils Myofibrils (( 1-2 µm) 1-2 µm) MyofilamentsMyofilaments

Actin & MyosinActin & Myosin

Myofilaments

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Page 9: Skeletal  Muscle  Tissue And  Organization

SarcomeresSarcomeres

Thick and Thin Filaments are organized in repeating functional units = ______

Each myofibril has linear arrangement of ~ 10,000 sarcomers

Banded appearance (striation) due to arrangement of thick and thin filaments

Interaction of thick and thin filaments responsible for skeletal muscle fiber contraction

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Page 10: Skeletal  Muscle  Tissue And  Organization

Sarcomere Structure

Z - lineZ - lineA- bandA- band

= dArk band= dArk bandI - bandI - band

= LIght band= LIght band

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Page 11: Skeletal  Muscle  Tissue And  Organization

Thin Filament: ActinThin Filament: ActinF-actinG-actin

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Page 12: Skeletal  Muscle  Tissue And  Organization

Thick Filament: MyosinThick Filament: Myosin

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Page 13: Skeletal  Muscle  Tissue And  Organization

Some Myoblasts do not fuse satelite cells in endomysium

regeneration of muscle

Development of Myofibers from

MyoblastsMyoblasts

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Page 14: Skeletal  Muscle  Tissue And  Organization

Motor UnitsMotor Units

= All muscle fibers that are controlled by a single motor neuron

The lower the ratio of muscle fibers to neurons, the more precise the movement can be!

Few cases 1: 1 relationship. Where?

Most cases: many muscle fibers (up to 2,000) : 1 motor neuron. Where?

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Page 15: Skeletal  Muscle  Tissue And  Organization

Muscle ControlMuscle tone = Resting tension of skeletal muscles

(continuous contraction of some motor units to maintain some muscle tension)

Recruitment or Multiple motor unit summation

Maximal tension production: ?

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Page 16: Skeletal  Muscle  Tissue And  Organization

Muscle Hypertrophy vs. Atrophy

Hypertrophy due to anaerobic exercise

Leads to increased muscle size - how?

Atrophy if supply of myofilaments exceeds demand. Muscle fibers become smaller and weaker.

Eventual death of muscle fibers is irreversible! Importance of Physical Therapy

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Page 17: Skeletal  Muscle  Tissue And  Organization

Three Types of Muscle FibersThree Types of Muscle Fibers

1) Fast (1) Fast (or Whiteor White) Fibers) FibersFast contraction after nervous stimulation

Large diameterlarge glycogen reserve

few mitochondria

densely packed myofibrils

Fatigue fast due to mainly anaerobic respiration

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Page 18: Skeletal  Muscle  Tissue And  Organization

2) Slow (or Red) Fibers2) Slow (or Red) Fibers

Slower but continuous contraction for extended periods

Smaller diameter (~ half)contain myoglobin

more capillaries

more mitochondria

Do not fatigue as fast due to ? Fig 9-13

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Page 19: Skeletal  Muscle  Tissue And  Organization

3) Intermediate Fibers3) Intermediate Fibers

Have attributes inbetween fast and slow types

Most skeletal muscles contain mixture of fiber types. Proportion of fast to slow depends on ___________?

One motor unit only contains one fiber type

Eye, hand: ____ fibers dominate

Back, calf: ____ fibers dominate

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Page 20: Skeletal  Muscle  Tissue And  Organization

Organization of Skeletal Muscle Fibers

Effect of individual muscle contraction

determined by:1. arrangement of muscle fibers2. way of attachment to skeletal system

Bundles of muscle fibers =

Muscle fibers within 1 fascicle are parallel

4 types of fascicle organizationwww.freelivedoctor.com

Page 21: Skeletal  Muscle  Tissue And  Organization

Parallel MuscelsParallel Muscels

Majority

Spindle shaped with cord-like tendons

Some flat bands with broad _____ on each end

Examples: ?

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Page 22: Skeletal  Muscle  Tissue And  Organization

Convergent muscelsConvergent muscels

Broad origin, pointed insertion

Direction of pull can be varied:versatility!!

Example

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Page 23: Skeletal  Muscle  Tissue And  Organization

Pennate Muscles: UnipennatePennate Muscles: UnipennateOne or more tendons run

though muscle body

Fascicles in oblique angle to tendon

Can generate more tension

Example

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Page 24: Skeletal  Muscle  Tissue And  Organization

Pennate Muscles: Pennate Muscles: Bipennate & Bipennate & Multipennate Multipennate

ExampleExample

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Page 25: Skeletal  Muscle  Tissue And  Organization

Circular Muscles Circular Muscles

= Sphincters

Concentric fibers adjust opening

Examples: orbicularis occuli and oris

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Page 26: Skeletal  Muscle  Tissue And  Organization

Muscle TerminologyMuscle Terminology

Origin stationary

Insertion moves

Possible: multiple origins

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Page 27: Skeletal  Muscle  Tissue And  Organization

Types of ActionsTypes of Actions

flexion, extension adduction, abduction elevation, depression rotation,

circumduction pronation, supination

etc. . . . .

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Page 28: Skeletal  Muscle  Tissue And  Organization

Grouping of Muscles according to Grouping of Muscles according to Primary ActionPrimary Action

Agonist = Prime Mover

Antagonist (action opposes agonist)

Synergists = Assistants of prime mover

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Page 29: Skeletal  Muscle  Tissue And  Organization

Anterior Thorax

Deltoid– IM injection site

Pectoralis– Major and minor

Serratus anterior

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Page 30: Skeletal  Muscle  Tissue And  Organization

The Arm, AnteriorAspect

•Biceps Brachii•Two Heads•Origin: Coracoid and Supraglenoid tubercle•Insertion: Radial Tubercle

•Brachialis•Brachioradialis•Digital Flexors

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Page 31: Skeletal  Muscle  Tissue And  Organization

The Arm, Posterior Aspect

•Triceps Brachii•Three Heads:

•Long•Lateral•Medial

•Carpal Extensors•Digital Extensors•Extensor retinaculum

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Page 32: Skeletal  Muscle  Tissue And  Organization

The Hand,Dorsal Aspect

•Extensor retinaculum

•Extensor tendons

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Page 33: Skeletal  Muscle  Tissue And  Organization

The Hand, Palmar Aspect

•Flexor Retinaculum AKA Transverse Carpal Ligament•Carpal Tunnel

•Irritates the median nerve

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Page 34: Skeletal  Muscle  Tissue And  Organization

The Pelvis

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Page 35: Skeletal  Muscle  Tissue And  Organization

The Thigh:Anterior View

•Quadriceps Group (4 heads) converge as the Quadriceps Tendon

•Vastus Lateralis•Vastus Medialis•Rectus Femoris•Vastus intermedius

•Iliotibial Tract•Sartorius

•Longest muscle in body

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