3
Riddler #2, answer Riddler #2, answer Answer: B – Answer: B – hypercalcemia a hypercalcemia a systemic disease, systemic disease, caused by up regulation caused by up regulation of calcitriol can cause of calcitriol can cause stones and kidney stones and kidney failure failure Bilateral anterior Bilateral anterior uveitis – treat with uveitis – treat with topical or locally topical or locally injected steroids injected steroids E. Nodosum and fever E. Nodosum and fever usually resolve in 6 usually resolve in 6 weeks w/o treatment weeks w/o treatment Persistent cough can be Persistent cough can be treated by inhaled treated by inhaled steroids/beta agonist steroids/beta agonist

Riddler Q3

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Page 1: Riddler Q3

Riddler #2, answerRiddler #2, answer

Answer: B – Answer: B – hypercalcemia a hypercalcemia a systemic disease, systemic disease, caused by up regulation caused by up regulation of calcitriol can cause of calcitriol can cause stones and kidney stones and kidney failurefailure

Bilateral anterior uveitis Bilateral anterior uveitis – treat with topical or – treat with topical or locally injected steroidslocally injected steroids

E. Nodosum and fever E. Nodosum and fever usually resolve in 6 usually resolve in 6 weeks w/o treatmentweeks w/o treatment

Persistent cough can be Persistent cough can be treated by inhaled treated by inhaled steroids/beta agoniststeroids/beta agonist

Page 2: Riddler Q3

Riddler #2, Bonus Riddler #2, Bonus AnswerAnswer Bonus:Bonus: Lofgren’s Syndrome: Lofgren’s Syndrome: Sven Sven

Löfgren contributed significant new insights Löfgren contributed significant new insights to the clinical features of sarcoidosis and to the clinical features of sarcoidosis and delineated a syndrome that often occurs at delineated a syndrome that often occurs at the onset of sarcoidosis in Caucasians, the onset of sarcoidosis in Caucasians, characterized by characterized by erythema nodosum, erythema nodosum, bilateral hilar lymphadenopathy, bilateral hilar lymphadenopathy, feverfever, , and and polyarthritis.polyarthritis.

Associated with a 80% spontaneous Associated with a 80% spontaneous remission rateremission rate

Page 3: Riddler Q3

Riddler #3Riddler #3 45 y/o male with 45 y/o male with

chest pain.chest pain.

What is the What is the diagnosis?diagnosis?

Bonus? The City Bonus? The City and State of the first and State of the first White House?White House?