Plant as a source of drugs

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PLANT AS A SOURCE

PLANT AS ASOURCE OF DRUGPresented by:NARAINO MAJIE NabiilahDate: 5th March 2013

CONTENTIntroduction of Natural DrugsGrowing interest in Natural SourcesDrug CollectionDrug ClassificationDrugs obtained from:RootBarkLeavesFlowersFruits & SeedsProblems related with Plant Sources

INTRODUCTIONOldest source of Drug

Home remediesReligious significancePure compounds easily obtainedStructural modification to produce potentially more active and safer drugsEconomical

WHY IS THERE A GROWING INTEREST IN NATURAL SOURCES?Efficient compared to conventional diseasesNo side effectsHarmlessDrugs against Anti-HIV and Anti-Tumour activity are from plant originDue to technological, economic, cultural and social trends.

DRUG COLLECTIONProper time of collection is very important to obtain a drug of good quality. It depends on the following:

Time of the yearTime of the dayStage of maturity and age

DRUG CLASSIFICATIONClassifications can be based on:

Chemical natureTherapeutic value of the plant product Natural affinities of the various speciesMorphology of the plant organ from which the drug is obtained

1-ROOTAconite obtained from the plant Aconitum napellus. It is used externally for neuralgia and arthritis, and internally to relieve fever and pain.

Licorice obtained from the plant, Glycyrrhiza glabra. It is used as a demulcent and expectorant and to disguise the flavor of medicinal preparations.

Rhubarb obtained from the plant Rheum officinale and R. palmatum. It is used as a tonic and laxative and for indigestion.

2-BARKQuinine obtained from Chinchona calisaya, C. officinalis, C. ledgeriana and C. succccirubra. It is used as the only adequate cure for malaria.

Slippery Elm obtained from Ulmus rubra. It is used for its soothing effect on inflamed tissues, either in the crude state or in the form of lozenges.

3-LEAVESBelladonna is obtained from Atropa belladonna. Belladonna is used externally to relieve pain and internally to cure excessive perspiration and coughs.

Cocaine is obtained from Erythroxylon coca. It is used as a local anesthetic and as a tonic for digestion and treatment of nervous conditions. It is addictive when used habitually.

Digitalis is obtained from Digitalis purpurea. Its action improves the tone and rhythm of the heart beats thereby making contractions more powerful and complete.

4-FLOWERSChamomile is obtained from Matricaria chamomilla. The dried flower heads contain an essential oil infusions which are used as tonics and gastric stimulants.

Hops is obtained from Humulus lupulus. Hops are used in medicine for their sedative and soporific properties and also as a tonic.

5-FRUITS & SEEDSOpium is obtained from Papaver somniferum. Due to the narcotic and sedative action opium and its derivatives are used to relieve pain, relax spasms and induce sleep.

Nux Vomica is drug obtained from the seeds of Strychnos nux-vomica. It is used as a tonic and stimulant; strychnine, an alkaloid of its ripe seed, is used in small doses to treat nervous disorders and paralysis.

PROBLEM RELATED WITH PLANT SOURCES

Identification of plantClimatic and social conditions of areaSeason of collectionCondition of storageStandardization of active principlePurity of active ingredientMaintenance of supply line

CONCLUSIONPlants have provided humans with many of their essential needs, including life-saving pharmaceutical agents. Recently the World Health Organization estimated that 80% people worldwide rely on herbal medicines.Many developing countries have intensified their efforts in documenting the ethnomedical data and scientific research on medicinal plants.

REFERENCEShttp://ns.bdnews24.com/blog/en/index.php/md-nasir-ahmed/1038http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658564/http://howmed.net/pharmacology/sources-of-drugs/http://www.faculty.ucr.edu/~legneref/botany/medicine.htm