1. MICRONBusiness Plan on API Micronization unit.Prepared by:Chandni Patel(10BPH049)Drashti Patel (10BPH051)Dhara Patel (10BPH052)Drashti Patel (10BPH054)Hina Patel (10BPH056)

2. COMPANY INFORMATION MICRON is a proposed Partnership firm which isentering into the world of micronized activepharmaceutical ingredient. The business project is intended to capitalize on theincrease in bioavailability of the drugs so they can getabsorbed easily and efficiently give its action. The project also helps the local formulation units toproduce the formulation with better effect.2 3. GoalMicron focuses on delivering innovative solutions to ourcostumers. We facilitate sustainable returns and providea dynamic and challenging environment for allstakeholders.3 4. PRODUCTs AND BENEFITS CHLORZOXAZONE : It is a muscle relaxant drug which ongetting micronized gives a 35% increase in itsbioavailability. GLYBENCLAMIDE : It is used in the treatment of type 2diabetes with the increased bioavailability by 17%. GLIMIPERIDE : It is an anti diabetic drug which onMicronization gives 20% increase in bioavailability.4 5. PRIMARY PRODUCTSGlimepride.GlybenclamideChlorzoxazone5 6. PROPOSED LOCATION Ankleshwar industrial estate. It is place in Bharuch. Pin code- 393002. It has good excess to many places as it is located near to theNH 8. Availability of raw material and labour is good. Wide spread API manufacturing and utilizing unit.6 7. PROMOTERS PROFILENameEducationalQualificationPercentage PartnershipChandni B. Patel(Financial Partner)B Pharm 35%Drashti N. Patel(Financial Partner)B Pharm 35%Dhara H. Patel(Technical Partner)B Pharm 10%Drashti R. Patel(Technical Partner)B Pharm 10%Hina A. Patel(Technical Partner)B Pharm 10%7MICRON is a Partnership firm of 5 budding Entrepreneurs. 8. TYPE OF PROJECTSmall Scale Processing unit with an installed production capacity of: Mill size diameter 12. Energy requirement :441.79 m3/hr. Capacity: 13- 113 Kg/hr.8 9. Product Type & Quality We will offer the micro fine Chlorzoxazone, with92% particles below 250 micron packed well infiber drum which shows the 35% increasedbioavailability. We offer the micro fine Glimepride, with 17%better antidiabetic effect packed in a fiber drum. we offer the micron sized Glybenclamide, packedin fiber drums with 20% increased bioavailability.9 10. MAJOR CONSUMERSAlpha Pharmaceutical10Genecia Health Care (Pvt.) LimitedAkums Drugs Pharmaceuticals Ltd.(Alcare) 11. Marketing strategy The company produces the Micronized API lower thanthe lowest price with High Quality material assured bythe reputed Quality Control Laboratories. Another thing is that the drug will be available in themarket as the companys manufacturing unit is placednearby the National Highways and shipment is alsonearer. Company also accepts mailing orders and manufactureaccording to International Requirements.11 12. Technical knowhow available Todays world has a great use of drugs but the greatproblem with its bioavailability. Thus one of thetechnique to increase the bioavailability is to do sizereduction (Micronization). We are using USDA-accepted designMICRONIZER JET MILL to get the well micronizedproduct.12 13. HOW DOES IT WORK13 14. Production process14Procure the APISubject to milling in MICRONIZERJET MILLPacking of material in fiber drum.Sell the micronized API 15. Basis & Presumptions We can run single shifts for 225 days in 1st year. MICRONIZER JET MILL can work at the rate of 13- 113Kg/hr. Thus approx of 200 kg of product can be micronized in aday excluding the time to wash the machine clean todecrease contamination. Project time from site selection to trial run is 4-5months.15 16. Implementation ScheduleSelection of site, provisionalregistration, project reportpreparation2 monthSanction of loan 1 monthSelection of machinery 1 monthCommissioning and trial run 5 to 7 months16Actual Implementation time is 4-5 months due to overlapping ofactivities 17. Production ScheduleTotal Capacity 200 kg / day.Capacity utilization1st year 80 kg /day2nd year 130 kg /day3rd year 170 kg /day17 18. Project detailsLAND AND BUILDING COSTSr. ParticularAreaRequired(m2) Rate Rs./m2 Total Value1 Land 300 4000 12000002 Building 200 275 55000Total Rs. 125500018 19. Equipment & Machinery19MICRONIZER JET MILL API Packing material 20. Equipment & Machinery costSr. No DescriptionNos.RequiredRate Rs.Total ValueRs.1MICRONIZER JETMILL3 50000 1500002 HVAC (AC) 1 25000 250003Miscellaneousinstruments1 75000 750004 Cart 3 200 600Total 25060020 21. Misc Fixed AssetsSr. No Particulars Total Value (Rs.)1Electrification and installation@10%383502Office Furniture andEquipments50000Total: 8835021 22. Preliminary & Pre-Operative ExpensesSr. No Particulars Amount (Rs.)1 Establishment Expenses ( Tech.Consultancy)100002 Non refundable deposits & Start-UpExpenses25000Total 3500022 23. Total fixed costCost Components AmountLand & Building Cost 1255000Equipment & Machinery 250600Misc & Fixed Assets 88350Preliminary & Preoperative35000ExpensesTotal 162895023 24. Sales revenueSr no Items(s)QuantitySold/YearRate perkg(Rs)SalesRealization(Rs)1 Chlorzoxazone 8000 105 8400002 Glybenclamide 2200 205 4510003 Glimiperide 4500 155 697500Total : 198850024 25. Raw Material (Monthly)Sr. No Items(s) Quantity Rate (Rs) Total Value(Rs)1 Chlorzoxazone 8000 97 7760002 Glybenclamide 2200 200 4400003 Glimiperide 4500 150 67500025 26. Utilities (Monthly)26Sr. Particulars Expenditure (Rs)1 Power/Electricity 20002 Water 10003 Fuel / compressed gas 4000Total 7000 27. Manpower (Monthly)Sr. no. Particulars No.Wages/Salariesper Month (Rs.)AnnualExpenses (Rs)1 Unskilled Person 3 1500 45002 Skilled Person 2 2800 56003 Operator 1 3500 35004 Shift Incharge 1 7000 7000Total7 Total 2060027 28. Repairs & Maintenance(monthly)Sr. No. Particulars Amount (Rs)1Repairs andmaintenance100028 29. Administrative Expenses(Monthly)Sr. Particulars Amount(Rs)1 Stationery & Printing 10002 Post/Telephone/Fax 10003 Guest Entertainment Expenses 4004 Misc. 2600Total 500029 30. DEPRECIATION ( Yearly)Sr. No. Type of AssetCost ofAssetDepreciation Amount1 Buildings 600000 10% 600002Plant &Machinery383500 20% 767003 Furniture 50000 20% 10000Total 14670030 31. WORKING CAPITAL(one month) / One CycleSr. No. Item Rs.1 Raw-Material 18910002 Salary/Labour 206003 Administrative expenses 50004 Repairs & Maintenance exp. 1000Total: 191760031 32. Total cost of the projectSr. no. Particulars Total Value (Rs.)1 Fixed Capital 16289502 Working capital ( One Cycle ) 19176003Preliminary & Pre-operativeExpenses35000Total 1672005032 33. Means of FinanceSr. No ParticularsPercentage ofloanAmount (Rs.)1Own investment (Total)60%11505601st finance partner 5000002nd finance partner 5000001st thinking partner 501862nd thinking partner 501863rd thinking partner 501862 Term loan 40% 767040Total: 191760033 34. Rate of return Rate of return in expected to be 1000 days (3 yearsapprox.)34 35. SWOT AnalysisSTRENGTHS It will provide new workopportunities. Innovation in product. Low cost of innovation andoperation.WEAKNESS Chances of failure. Unstable political situation. Stringent prize regulationaffecting the profitability ofpharma companies.OPPORTUNITIES Many companies can not affordthis machinery but the use onmicronized product is must. Large demand for qualityservices.THREATS New emerging companies. Decrease in the use ofmicronized product. Wages inflation.35 36. THANK YOU36