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Linda Hope Senior Industry Specialist Edgewater Fullscope See What’s New In R2 How Microsoft Dynamics AX R2 addresses potency, sequencing and lot inheritance

5 Manufacturing R2 Enhancements Life S

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Page 1: 5 Manufacturing R2 Enhancements Life S

Linda HopeSenior Industry SpecialistEdgewater Fullscope

See What’s New In R2How Microsoft Dynamics AX R2 addresses potency, sequencing and lot inheritance

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Process Manufacturing R2 – Enhancements

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Process Manufacturing R2 – Enhancements

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Process Manufacturing R2 – Enhancements

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Potency Management

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Potency managementPotency is the measurement of active material in a specific lot, normally expressed in terms of an active unit.*

* APICS Dictionary (American Production and Inventory Control Society)

Active ingredients

Compensating ingredients

Filler ingredients

Other ingredients

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Compensating

.

C

Active and Compensating ingredientsOpposing effectStandard Potency

% Caustic

Potassium Hydroxide

Sodium Hydroxid

e

As Potency increases, less Quantity of the

Active Ingredientis required

As less Quantity is needed, more Compensating

Quantity is required

Active

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Compensating

.

C

Active and Compensating ingredientsOpposing effectStandard Potency

% Caustic

Potassium Hydroxide

Sodium Hydroxid

e

As Potency decreases, more Quantity of the

Active Ingredientis required

As more Quantity is needed, less Compensating

Quantity is required

Active

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Active and Compensating ingredientsComplimentary effect

OliveOil

As Potency decreases, more Quantity of the

Active Ingredient is required

As more Quantity is needed, more Compensating

Quantity is required

ActiveStandard Potency

% Fatty Acid

Compensating

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Active and Compensating ingredientsComplimentary effect

OliveOil

As Potency increases, less Quantity of the

Active Ingredient is required

As less Quantity is needed, less

Compensating Quantity is required

ActiveStandard Potency

% Fatty Acid

Compensating

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Active and Compensating ingredientsComplimentary and Opposing effect

Active Compensating

Compensating

Complimentary Effect

OpposingEffect

Compensation Principle

Filler

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12

System Demonstration

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Batch Balancing in Production

•Define the batch production formula interactively based on the concentration of key ingredients.–Easily select inventory batches or lots based on current potency of the Active ingredient–Automatically calculates the required Active ingredient quantity–Determines quantities needed for any Compensating or Filler ingredients–Updates the batch production formula based on the adjusted formula

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Batch Balancing in Production•Define the batch production formula interactively based on the concentration of key ingredients.–Easily select inventory batches or lots based on current potency of the Active ingredient–Automatically calculates the required Active ingredient quantity–Determines quantities needed for any Compensating or Filler ingredients–Updates the batch production formula based on the adjusted formula

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Batch Balancing in Production

A batch of lower concentration (42.5%) has been selected which results in a increased required quantity for the Active ingredient.

When the Balance batch ingredients is clicked, the Balanced quantity for the Compensating, Filler and other ingredients are calculated.

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Batch Balancing in Production

A batch of lower concentration (42.5%) has been selected which results in a increased required quantity for the Active ingredient.

When the Balance batch ingredients is clicked, the Balanced quantity for the Compensating, Filler and other ingredients are calculated.

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Attribute-based Pricing & Accounting Pay Suppliers and value inventory based on the active ingredient quantity received.

85% Active

= $655.5

0

50Gallon

s50

Gallons

82.5% Active

= $636.2

2

50 Gallons

86.7% Active

= $668.6

1

Price calculation may vary by supplier and item

Most common price calculation: Price / Target Potency * Actual Potency received

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Attribute-based Pricing

Set purchase price and inventory value based on the received item’s concentration Required in chemical industries

where potency fluctuates from batch to batch

Required in oil and specialty chemical industries where pricing is based on percentage caustic, acids, or other intrinsic efficacies

Standard business practice for pricing precious metals

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Attribute-based Pricing

• Provides a flexible formula that allows companies to pay their suppliers based on the actual results for potency

• Assigns actual inventory value for each inventory batch that is potency price controlled

• Margins will be computed based on the actual potent value of materials sold or consumed

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20

System Demonstration

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Batch Order Sequencing

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• Ability to sequence products on a resource according to a defined priority based on product characteristics– Ability to define Sequences and Sequence groups– Assign Sequences to items– Assign Sequence groups to resources– Apply Sequence principle to the master schedule

Batch Order Sequencing

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From this…

Batch Order Sequencing

To This…Flavor – Pack Size - Tablet Size

Cleanup!

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Batch Order SequencingSimple Sequencing : Flavor

Grape

Banana

Orange

Minimizes ChangeoverAnd Cleanups

Lemon

Chocolate

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Batch Order Sequencing

Safe Sequencing : Drugs

Ensure different products that look similar are never sequenced to follow each other

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Batch Order Sequencing

Using multiple sequences ranked within a sequence group provides the desired sequence

Sequence 2: Pack Type

Sequence 1: Flavor

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27

System Demonstration

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Lot Inheritance

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Lot Inheritance

• Ability to automatically transfer properties of a raw material batch to a manufactured item’s batch

• Transfer key batch characteristics (batch attributes)

• Transfer shelf life date properties

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Lot Inheritance: Chemicals

Chemical 123

Batch AttributesAppearance white crystalline substanceMelting point app. 65°CSolubility in water 680 g/l (20°C1400 g/l (60°C)Alkaline resistance goodAcid resistance decompositionOdour slight internal odourDelivery form powder, granulesHS-Code 28 31 10 00

Batch AttributesAppearance white crystalline substanceMelting point app. 65°CSolubility in water 680 g/l (20°C1400 g/l (60°C)Alkaline resistance goodAcid resistance decompositionOdour slight internal odourDelivery form powder, granulesHS-Code 28 31 10 00

Co-Product A

Batch AttributesAppearance white crystalline substanceMelting point app. 65°CSolubility in water 680 g/l (20°C1400 g/l (60°C)Alkaline resistance goodAcid resistance decompositionOdour slight internal odourDelivery form powder, granulesHS-Code 28 31 10 00

Co-Product B

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Lot Inheritance: Pharmaceuticals

Human Skin TissueBlood Type: O +

Cell Culture 1Blood Type: O +

Cell Culture 2Blood Type: O +

Cell Culture 3Blood Type: O +

Cell Culture 4Blood Type: O +

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Lot Inheritance: Shelf Life

Example: Assembly

Expiry Date: 12/21/2012

Expiry Date: 12/19/2012

Expiry Date: 12/17/2012

Assembly Components

Assembly will inherit the earliest shelf life of 12/17/2012

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33

System Demonstration

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Lot Inheritance

Example: Consumed inventory lots include these attributes and shelf life

Shelf Life: Earliest Expiration date is 04/01/2013

Attribute Values: Unique attributes and values for each item and batch

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Lot Inheritance

Example: Batch for the formula item includes the batch attributes and shelf life dates of the consumed raw material batches

Inherits attributes of consumed lots and their respective values

Inherits earliest expiry date for consumed batches

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Process Manufacturing R2 – Enhancements