View
2.644
Download
0
Category
Tags:
Preview:
DESCRIPTION
Ed Nemeth tells his personal compelling story abut hyperbarics and how he discovered the benefits of HBOT. His exploration into HBOT led him to open his own clinics in Sacramento where he met and treated retired football player George Visger.
Citation preview
www.CHERISHfoundation.orgIndep. Football Veterans Conf. March 25, 2011
NFL Brain Injuries, Treatments & Medical
Rights
Ed NemethRebecca’s Dad
Hyperbaric Oxygen Therapies
www.CHERISHfoundation.orgIndep. Football Veterans Conf. March 25, 2011
Who am I?
The loving and faithfulfather of Rebecca,
a severely disabled child!
Hyperbaric Oxygen Therapies
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Who am I?
Rebecca’s Dad!
Trained as a scientist - objective Researched nerve regeneration /
plasticity Department of Neurobiology, University of Vermont Medical School
Businessman / Entrepreneur - pragmatic
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Our Journey Birth, Death &
Resuscitation
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Our JourneyComa
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Our Journey~~ The Journey! ~~
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Our Journey~~ The Journey! ~~
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Our JourneyHypberbaric Oxygen!
Dismissed HBOT in 1998
Struggled to get help for Rebecca Mouth-to-mouth rescusitation 9 times 1-hour long static gran mal seizures monthly Bronchitis & pneumonia 6 times a year Weak, myriad challenging problems
Then…. Surgical Neurology, vol 10 Oct. 78 Ischemic Penumbra reversed @ 7 years post
injury HBOT “had to” work!
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
What we did!
Went to Dr Neubauer’s HBOT Clinic in Florida For Hyperbaric Oxygen Therapies - HBOT
40 Sessions in 2 months July-August, 2000
Great immediate responses Horrible SPECT scans 2nd SPECT’s showed great response!
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Fantastic Changes!
Went seizure and drug FREE for 6 years! Could maintain own body temp. at
night! Pneumonias and bronchitis STOPPED! Feeding time dropped from:
1 hour 10 minutes to 20 minutes! Gained coordination (had NONE!)! Gained endurance and strength (had
NONE!)!
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
SPECT Scans Single Photon Emission Computed Tomography
Uses Ceretec radio-isotope Crosses blood brain barrier (BBB) Binds to active neurons
Objective View function, not structure Compares CNS metabolism
before & after HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
SPECT Scans Single Photon Emission Computed Tomography
Uses Ceretec radio-isotope Crosses blood brain barrier (BBB) Binds to active neurons
Objective View function, not structure Compares CNS metabolism
before & after HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Clear Benefits - SPECT Scans Pre HBOT Post 36 HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Clear Benefits - SPECT Scans Post 36 HBOT Post 4
Month Rest
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Clear Benefits - SPECT Scans Post 4 Month Rest Post 32 HBOT
(add’l)
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Clear Benefits - SPECT Scans Pre HBOT Post 72 HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
at 2.4 ATA HBOT delivers O2 = HbO2 desaturation HBOT creates high O2 gradient & O2 activity
HBO Effect on Blood O2 Content
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Depth Application
0 fsw; 1 ATA16.5 fsw; 1.5 ATA
33 fsw; 2 ATA49.5 fsw; 2.5 ATA59.4 fsw; 2.8 ATA
66 fsw; 3 ATA165 fsw; 6 ATA
Sea levelChronic Brain InjuryBurnsDiabetic Wounds/OsteoCO PoisoningAcute Cyanide
PoisoningAcute Decompression
Illness
www.CHERISHfoundation.orgIndep. Football Veterans
Conf. March 25, 2011Hyperbaric Oxygen
Therapies
HBOT Mechanisms
Multiple mechanisms Angiogenisis Neural re-activation *
Normalization of oxygen deficit Re-establish neuronal metabolism Neuronal Regeneration
Increase natural stem cells 800%* Ischemic penumbra is now accepted as the
primary cause of deficits
www.CHERISHfoundation.org
How it works - 5,769+* ways* Oxygen-sensitive outcomes and gene expression in acute ischemic stroke. Rink C, Roy S, Khan M, Ananth P, Kuppusamy P, Sen CK, Khanna S. J Cereb Blood Flow Metab. 2010 Feb 10.
Up-regulates growth factors
Reduces edema Increases neuronal ATP Enhances Mitochondrial:
Replication Energy Production (ATP)
Promotes neural pathway growth
Stimlates aging neurons Down-regulates
inflammation Reduces reperfusion
injury
Indep. Football Veterans Conf. March 25, 2011
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
HBOT Benefits - SPECT Scans
Pre HBOT Post 72 HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
HBOT Is Very Safe
From a 10 year study of 1,505 patients receiving 52,758 2-hour HBOT sessions at 2.4 ATA once or twice daily.
inability to equalize middle ear pressure 0.37% paranasal sinus blocks 0.09% confinement anxiety 0.05% oxygen convulsions 0.009% pulmonary oxygen toxicity 0.00% permanent ocular refractive changes 0.00%
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
USA Today 1998:
16,500 died from gastrointestinal bleeding taking NSAIDs (1997)
…...yet is fully accepted.
Comparative Drug Safety
www.CHERISHfoundation.org
Different HBOT Chambers
Multi-place Chamber
www.CHERISHfoundation.orgHyperbaric Oxygen
Therapies
Mono-place Chamber
Different HBOT Chambers
www.CHERISHfoundation.org
Different HBOT Chambers
Home Chamber
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
SPECT Scans Single Photon Emission Computed Tomography
Uses Ceretec radio-isotope Crosses blood brain barrier (BBB) Binds to active neurons
Objective View function, not structure Compares CNS metabolism
before & after HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
War Veteran TBIBefore & After HBOT
www.CHERISHfoundation.org
NFL Player: TBI impact assessment
NFL football player with concussion
Loss of about 2% of the fiber tracts in the region of the corpus callosum.
Area of Tissue change Fibers passing through areas
Enlarged Fiber Tract showing fibers from concussive event
Courtesy Dr. Walter Schneider, U Pittsburgh
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
NFL Veteran TBIBefore HBOT
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
NFL Veteran TBIAfter HBOT
www.CHERISHfoundation.org
Case Presentation Alzheimer’s Disease
Scan #1
Scan #2
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Medicare Reimbursed IndicationsHBOT increases tissue O2
Compromised Skin (Acute traumatic peripheral ischemia)
Compromised Skin Grafts Burns Chronic Refractory Osteomyelitis Diabetic Wounds Clostridial Myonecrosis (Gas Gangrene) Progressive Necrotizing Infection (Meleney’s Ulcer)
Soft Tissue Radiation Necrosis Osteoradionecrosis Acute Peripheral Arterial Insufficiency (ulcers) Actinomycosis
Acute Cyanide Poisoning Carbon Monoxide Poisoning (acute) Intravascular Gas Embolism Decompression Illness
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Non-healing Wounds
1) 1 year mainstream medicine2) 26 HBOT’s later3) 50 HBOT’s later
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
HBOT for
Burns
Textbook on Hyperbaric SurgeryBakker MD, Cramer MD
Summary:
Control HBOTBurn (%) 48% 61.8%Days Hosp. 108 51.8Surgeries 7.8 2.1Costs $391k $215kScarring (reduced 95%)
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
SB2046 Mandates HBOT Reimbursement
California SB 2046 in its amendments to:
• H&S Code 1367.21; • W&I 14105.26; • Insurance Code 10123.195
Mandates reimbursement for FDA Approved, “off label” drugs, that meet specific criteria - HBOT qualifies under those criteria.
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
California SB 2046 “prohibits a health care service plan contract, and specified disability insurance policies, from limiting or excluding coverage for a drug on the basis that the drug is prescribed for a use different than the use for which the drug has been approved for marketing by the federal Food and Drug Administration (off-label use) if specified conditions are met, including that the drug prescribed is for the treatment of a life-threatening… chronic and seriously debilitating conditions.”
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
1367.21. (a)…. provided that all of the following conditions have been met:
(1) The drug is approved by the FDA.
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
1367.21. (a)…. provided that all of the following conditions have been met:
(2)(B) The drug :is prescribed by a physician for treatment of a debilitating
condition,is medically necessary is on the plan formulary.
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
1367.21. (a)…. provided that all of the following conditions have been met:
(3) The drug has been recognized for treatment of that condition by one of the following:
(D) Two articles from major peer reviewed medical journals supporting the proposed off-label use as safe and effective.
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
(D) Two articles from major peer reviewed medical journals supporting the proposed off-label use as safe and effective.
Golden ZL, Neubauer RA, Golden CJ, et al.: Improvement in cerebral metabol-ism in chronic brain injury after hyperbaric oxygen therapy. Int J Neurosci 2002, 112:119-131.
Harch PG, Gottlieb SF, Van Meter KW, Staab P. HMPAO SPECT brain imaging and low pressure HBOT in the diagnosis and treatment of chronic traumatic, ischemic, hypoxic and anoxic encephalopathies. Undersea & Hyperbaric Medicine, 1994; 21(Suppl):30.
Harch PG, Fogarty EF, Staab PK, Van Meter K. Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report. Cases J. 2009 Jun 9; 2:6538.
Lin JW, Tsai JT, Lee LM, Lin CM, Hung CC, Hung KS, Chen WY, Wei L, Ko CP, Su YK, Chiu WT. Effect of hyperbaric oxygen on patients with traumatic brain injury. Acta Neurochir Suppl. 2008; 101:145–9.
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
(D) Two articles from major peer reviewed medical journals supporting the proposed off-label use as safe and effective.
Lin JW, Tsai JT, Lee LM, Lin CM, Hung CC, Hung KS, Chen WY, Wei L, Ko CP, Su YK, Chiu WT. Effect of hyperbaric oxygen on patients with traumatic brain injury. Acta Neurochir Suppl. 2008; 101:145–9.
Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report Paul G Harch, Edward F Fogarty, Paul K Staab and Keith Van Meter
Neubauer RA, Gottlieb SF, Pevsner NH: Hyperbaric oxygen treatment of closed head injury. South Med J 1994, 87:933-936.
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
(D) Two articles from major peer reviewed medical journals supporting the proposed off-label use as safe and effective.
Palzur E, Zaaroor M, Vlodavsky E, Milman F, Soustiel JF. Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties. Brain Res. 2008; 1221:126–33. Epub 2008 May 11.
Rockswold SB, Rockswold GL, Defillo A. Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007; 29:162–72.
Shi XY, Tang ZQ, Xiong B, Bao JX, Sun D, Zhang YQ, Yao Y. Cerebral perfusion SPECT imaging for assessment of the effect of hyperbaric oxygen therapy on patients with post brain injury neural status. Chin J Traumatol. 2003; 6:346–9.
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
(D) Two articles from major peer reviewed medical journals supporting the proposed off-label use as safe and effective.
Tinianow CL, Tinianow TK, Wilcox M. Effects of hyperbaric oxygen on focal brain contusions. Biomed Sci Instrum. 2000; 36:275–81.
UHM 2009, Vol. 36, No. 6 – Treatment of mild traumatic brain injury with hyperbaric oxygen
391 Case report: Treatment of mild traumatic brain injury with hyperbaric oxygen
Colonel James K. Wright, Eddie Zant, Kevin Groom, Robert E. Schlegel, Kirby Gilliland
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
California SB 2046
“A willful violation of the provisions
governing health care service plans
is a crime. ”
SB2046 Mandates HBOT Reimbursement
www.CHERISHfoundation.orgIndep. Football Veterans Conf.
March 25, 2011Hyperbaric Oxygen
Therapies
Rebecca Thanks you!
Recommended