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Why did I miss that patent?
How the value-added databases of STN® helps you to
find those missing patents
Makarand Waikar
ACSI-India
II-PIC 2017
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
The amount of data available today is overwhelming!
2
Sometimes it feels like even though the
search may be complete, the hunt is just
beginning!
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Hunting relevant information can be tricky
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Variety of sourcesVariety of sourcesComplexity of structuresComplexity of structures
Vast number of patenting countries
Vast number of patenting countries
Artfully written patentsArtfully written patents
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Comprehensively retrieving chemical patents
poses challenges
▪ Patents don’t always include:
• Substance names
• Chemical structures
• Physicochemical data
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
A prior art search for this anti-glaucoma substance
using only its chemical name misses WO2015117024
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2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-3-[(phosphonooxy)methoxy]-, sodium salt (1:2), (3S,4R)- (CA INDEX NAME)
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
The name search misses the patent because the
patent provides only the compound’s structure
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Retrieve the missing patent by including its chemical
structure and/or CAS Registry Number® in your search
The CAS chemist who
analyzed this patent found
the CAS RN for this
substance and included it
in the patent’s indexing.
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
What is a CAS Registry Number?
▪ A unique numeric identifier for a publicly disclosed substance
– Assigned to organic compounds, inorganic compounds,
enzymes, protein sequences, nucleotide sequences,
coordination compounds, alloys, minerals, polymers, etc.
▪ CAS created and maintains the CAS REGISTRYSM database, and
is the only organization that can provide authoritative CAS Registry
Numbers
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Is it possible to retrieve a substance of interest from
a patent which doesn’t provide its name or structure?
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Intellectual analysis by CAS scientists allows you to
retrieve the “missing” patent
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WO2002014342
• No name provided
• No structure provided
• But the synthesis and NMR
details of the “desired
product” allowed the CAS
scientist to determine the
structure of the product, and
to index its CAS RN in the
CAplusSM record for this
patent CAS RN 203796-03-6
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Can you still retrieve a patent when it lacks the
substance name, structure and physicochemical data?
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▪ Searched for the substance below
as a nematocide
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
The patent includes a Markush table with hundreds
of substances
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Your search in CAplus retrieves the patent because
CAS analysts index the substances in the table
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1648720-74-4
1648720-70-0
1648720-71-1
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Finding patents is one thing, but finding your
substance within the full text also poses a challenge
▪ Full text patents can be thousands of pages long!
▪ Substances may be difficult to find if they are: – In large tables
– Represented as structures including stereo
– In long lists of IUPAC names
– Vaguely described with terminology such as
“desired compound”
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
PatentPak® on STN allows you to instantly find the
location of the substance of interest in the patent
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Searching for numeric properties is challenging
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Heat transfer rate in the heat exchanger tube is improved due to use of fin structure portion that is formed in the pipe… internal surface of fin is less than 2000 microns.
Novelty of the invention :
How can you search the “less than 2000 microns” concept?
1. Less than 2000 microns can be 100 or 110 or 120 or 126 or 500 or
700 or 1999 ….
2. The value could be also expressed in other units in the original
patent other than microns – e.g., mm, cm, inches, etc.
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
A text-based search would be tedious and lengthy
▪ S heat exchanger AND ((1 micron or 2 microns or 3 microns …..
100 microns or 150 microns or 200 microns or 250 microns or
230 microns or 300 microns ….500 microns or 501 microns
or…… 2000 microns or 0.1mm or 0.2mm or 0.3mm or 0.4mm
or 0.5mm …. 1mm or 1.2mm or 1.3mm or 1.5mm…. or 1.9mm
or 1.95mm or 2mm or 0.1millimeter or 0.2millimeter or
0.3millimeter or 0.4millimeter or 0.5millimeter …. 1millimeter
or 1.2millimeter or 1.3millimeter or 1.4 millimeter or
1.5millimeter …. or 1.9millimeter or 1.95millimeter or
2millimeter ) ………
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Use STN’s value-added numeric property indexing to
find relevant patents in Derwent World Patent Index®
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AB US20170106984 A1 NOV NOVELTY - The heat exchanger (100) has several ram air layers that direct air.
The each ram air layer is a single pass layer which includes several ram air fins in fluid communication with the ram air flow. The several liquid pass layers is a five pass layer includes several liquid pass fins in fluid communication with the liquid flow. The each of the several liquid pass layers is positioned adjacent to the ram air layer of several ram air layers. The liquid pass fins has a liquid pass fin height of 0.058 inches.
ADV ADVANTAGE - The heat from the liquid coolant is effectively removed fromthe liquid and transferred to the air to allow for effective PECSoperation. The enhanced heat transfer is allowed, by five pass circuitof the liquid layer. The heat exchanger is dimensioned for proper mountingwithin a desired location, and structural rigidity is provided to theliquid layers.
0.058 inches= 1473 microns0.058 inches= 1473 microns
S HEAT EXCHANGER AND 0.00-2000 MICRON/LEN
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
A total of 55 numeric property search fields can be
searched in 19 patent and scientific databases ▪ STN extracts, normalizes and indexes the numeric data –
adding value to patent documents
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
STN offers a unique numeric property searching
solution
▪ Understands multiple units (e.g., metric and non-metric
measurements)
▪ Handles ranges of values
▪ Includes tolerances for values
▪ Allows you to search unstructured text for these values
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Challenges in searching generic compounds
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How can one search structures disclosed generically in claims?
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
STN has the first ever unified Markush search solution!!
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Many searches begin by looking into
exemplified structure databases
▪ A team of scientists prepared the
moiety shown for treating
gastrointestinal disorders. Is the
substance novel?
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Specific structure search results indicate all clear
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CAS Registry and Derwent Chemistry resource (DCR) gave zero hits, indicating that the structure is not disclosed specifically in any patent indexed in those databases.
CAS Registry and Derwent Chemistry resource (DCR) gave zero hits, indicating that the structure is not disclosed specifically in any patent indexed in those databases.
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
But Markush search results tell another story!
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MARPAT® gave 4 hits, the Derwent Markush Resource (DWPIM) gave 3.
Here methyl matches to lower alkyl (1-4 carbons).
The patent discusses substances generically as gastric secretion inhibitors.
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
Assembled hit structures in MARPAT can tell a more
complete story of what is hidden in a patent
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MARPAT assembled Hit Results show how the generic structure matches your query.
Original Patent
CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved.
STN can help you be confident that your search
results didn’t miss an important patent
▪ Find relevant information even if the chemistry is obscured
▪ Use STN’s value-added patent databases such as CAplus and Derwent
World Patents Index to increase comprehensiveness
▪ Save time by using PatentPak to locate substances within full text patents
▪ Find substances in STN’s Markush databases, MARPAT and Derwent
Markush Resource (DWPIM)
▪ Human curated, value-added indexing also featured in databases
focused on science, technology, engineering and medicine
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CAS is a division of the American Chemical Society.Copyright 2017 American Chemical Society. All rights reserved. 28
@STN
www.stn.org
Makarand WaikarFor any additional information, please feel free to contact us at
info@acs-i.org
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