Nutraceuticals= "Nutrition" and "Pharmaceutical"

By:

SHOAIB AHMED SHARIEF

Topic: NUTRACEUTICALS

CONTENT

HISTORY

INTRODUCTION

CONCLUSION

BIBLIOGRAPHY

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HISTORY

• The Greek physician Hippocrates, often known as the

“father of medicine” said “let food be your medicine”.

The Philosophy behind is:

“Focus on Prevention” • The term "Nutraceutical" was coined by combining the

terms "Nutrition" and "Pharmaceutical" in 1989 by

Dr. Stephen DeFelice.

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• According to Dr. DeFelice , “Nutraceutical is any

substance that is a food or a part of food that provides

medicinal or health benefits including the prevention and

treatment of disease.”[1]

• Health ministry of Canada defines it “As a product isolated

or purified from the food generally sold in medicinal form

not assisted with food and demonstrated to have a

physiological benefit and provide protection against

chronic disease.”[2]

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Introduction

• The Plants or herbs particularly Fruits and

Vegetables are the cheapest and most common store

of Nutrients i.e:-

• Carbohydrates

• Proteins

• Vitamins

• Minerals

• And essential amino acids

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Classification of Nutraceuticals

1. Potential Nutraceuticals - one which has promising

approach towards particular health or medicinal benefit.

2. Established Nutraceuticals – A Potential Nutraceutical

becomes Established Nutraceutical only after there are

sufficient clinical data to demonstrate such a benefit.

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Classification based on source

1. Plants - Tomato, Garlic, Momordica

2. Animals - Shark liver oil, Cod liver oil

3. Minerals - Calcium, Magnesium, Phosphorous

4. Microorganism - Bifidobacterium, Lactobacilli

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Nutraceuticals mainly consists of :

1. Nutrients: Substances which have established

Nutritional functions e.g. Vitamins, Minerals, Amino

Acids, Fatty acids, etc.

2. Herbals/ Phytochemicals: Herbs or Botanical products

3. Dietary Supplements: Probiotics, Prebiotics,

Antioxidents, Enzymes, etc.

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Raaz et al. 2011.

1. NUTRIENTS

Most common

Nutrients used as

Nutraceutical are:

• Minerals and

Vitamins.

• or in combination of

both.

• or in combination with

other antioxidants

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Minerals

2.Herbs

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3. Dietary supplements:

Probiotics- Live microorganisms which, when

administered in adequate amounts, confer a health benefit

on the host

Species of Lactobacillus

Yeast Saccharomyces Cerevisiae

some E. Coli and Bacillus species are also used as

probiotics• Probiotics have been shown to have applications in

alleviating symptoms of allergies, cancer, AIDS, respiratory and urinary tract infections.

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Avrelija and Walter , 2010

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Shorten Duration of Intestinal Infections

Treat Diarrhea

Improve Symptoms of

Irritable Bowel Syndrome

Reduce Bladderand Urinary

Tract Infections

ManageLactose

Intolerance

PotentialBenefits ofProbiotics

Prebiotics- Nondigestible substances that provide a

beneficial physiological effect for the host by

selectively stimulating the favorable growth of a

limited number of indigenous bacteria.

Commonly known prebiotics are:

• Oligofructose .

• Inulin

• Galacto-oligosaccharides

• Lactulose

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Areas covered by Nutraceuticals : All therapeutic areas such as,

1. Anti- Arthritic (Rheumatoid Arthritis)

2. Sleeping disorders

3. Digestion problems

4. Prevention of certain cancers (Colorectal cancer)

5. Osteoporosis

6. Blood pressure

7. Cholesterol lowering (garlic)

8. Neurological disorders (Autism)

9. Diabetes etc..

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Dietary polyphenols as potential nutraceuticals in management of diabetes

by Bahadoran et al. 2013.

23/12/2013 M.Tech Seminar- I Dept. of Chemical Engg. 19

Mahima et al. 2013

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23/12/2013 M.Tech Seminar- I Dept. of Chemical Engg. 21

Nutraceuticals may range in the form of :

• isolated nutrients,

• dietary supplements,

• genetically engineered “designer” food,

• herbal products,

• and processed products such as cereals, soups, and

beverages

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Sarin et al. 2012.

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Future Developments of Nutraceuticals

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Conclusion

Nutraceuticals may be beneficial to our health but we are still

learning about their benefits and possible harmful effects.

Government regulatory bodies also face challenges in this

new category of health products, which lies between foods

and drugs.

Health professional , Nutritionists and regulatory toxicologist

should strategically work together to plan appropriate

regulation to provide ultimate health and therapeutic benefit

to mankind. 26

Bibliography

1. Brower V. “Nutraceuticals: poised for a healthy slice of the healthcare market”

Nat. Biotechnol.1998, 16, 728-731.

2. http://www.hc-sc.gc.ca/sr-sr/biotech/about.apropor/gloss-eng.php(assessed on 23

sep 2010)

3. Raaz .M; Priyanka S; Bina R; Chauhan AK. “Healthy living with Nutraceuticals”

International Research Journal of Pharmacy 2011,2(12),12-14

4. Bahadoran Z; Parvin M; Fereidoun A. “Dietary polyphenols as potential

Nutraceuticals in management of diabetes” Journal of Diabetes & Metabolic

Disorders 2013,12:43

5. Mahima ; Amit K; Ruchi T; K Karthik” Nutraceuticals from fruits and vegetables at

glance” . Journal of Biological sciences 2013,13(3):38-47

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6. Avrelija C and Walter C “ The role of functional foods, Nutraceuticals and food

suplements in intestinal health” Nutrients 2010, 2, 611-625; doi:

10.3390/nu2060611

7. Sarin R; Sharma M; Singh R; Kumar S ” Nutraceuticals” International Research

Journal of Pharmacy 2012, 3 (4)

8. Prasuram RR ; Rawat B ; Thangavel S “ Nutraaceuticals : An Area of

Tremendous Scope” International Research Journal of Pharmacy 2011, 2(2) 410-

415

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THANK YOU

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