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• Neuroglia (glial cells)– Support, nourishment, protection to neurons–Most common site for tumors in CNS– Types• Micorglia• Oligodendroglia• Astrocytes• Ependyma
• Afferent vs Efferent– Afferent: sensory to spinal cord or brain– Efferent: motor away from spinal cord of brain
• Neurotransmitters– Act to facilitate transmission of impulse – Inactivated by enzyme
– Types• Excitatory• Inhibitory
• Neurotransmitter Systems in Brain– Noradrenaline (noradrenergic)– Dopamine (dopaminergic)– Histamine (histaminergic)– Serotonin (serotonergic)– Acetylcholine (cholinergic)
• Cerebral Metabolism– O2
• 20% CO, 20% of O2 delivered
–Massive Energy Needs• No Insulin requried!• Hypoglycemia
– Neuro Change (50 – 70 mg/dL)– Coma (20mg/dL)
• Hyperglycemia– Osmotic effect – brain dehydration
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