Life after sepsis - is it worth living?

Life after sepsis – is it worth living?Professor Simon Finfer MBBS FAHMS FRCP FRCA FCICM DrMed

sfinfer@georgeinstitute.org.au@icuresearch

Royal North Shore Hospital

Sepsis: Life threatening condition that arises when the body’s response to infection damages the

patient’s tissues and organs

Beyond hospital discharge …

The price for success?

Iwashyna and Angus JAMA 2014

What about the survivors?

What about the survivors?

Prevalence of moderate/severe cognitive impairment increased >10%

High rate of new functional impairments

Declines in cognitive/functional impairment persisted > 8 years

The lingering consequences of sepsis

Longitudinal analysis of the Health and Retirement Study3-fold increase in moderate/severe cognitive impairment3-fold increase in physical function impairment

Neurocognitive defects

PSS = PICS or different?

Life after sepsis – post-sepsis care

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