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Importance of vitamin d in orthopaedic patients
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Importance of Importance of Vitamin D In Vitamin D In
Orthopedic PatientsOrthopedic Patients
OSTEOPOROSISOSTEOPOROSIS
is highly prevalent, affecting approximately
one-third of women aged 60-70 years, and
two-thirds of those aged 80 years and older
200 MILLION WOMEN 200 MILLION WOMEN
WORLDWIDEWORLDWIDE
OSTEOPOROSISOSTEOPOROSIS is the major cause of
FRACTURESFRACTURES
1992;7:1005-10
40% OF WOMEN40% OF WOMEN and 13% of men
aged 50 years and older will sustain an
OSTEOPOROTIC FRACTUREOSTEOPOROTIC FRACTURE
in their remaining lifetime
1992;7:1005-10
FRACTURESFRACTURES have a profound impact on
QUALITY OF LIFEQUALITY OF LIFE.
Approximately 20%-25%20%-25% of women over age 50
years have had one or more
VERTEBRAL FRACTUREVERTEBRAL FRACTURE, the
most common osteoporotic fracture
Both vertebral and hip fractures are associated with excess
mortality. For instance, approximately 20% OF 20% OF
HIP FRACTURE PATIENTSHIP FRACTURE PATIENTS
aged 50 years and older
DIE WITHIN 1 YEARDIE WITHIN 1 YEAR
2001;285:320-3
Patients being treated for
OSTEOPOROSISOSTEOPOROSIS should
be adequately supplemented with
calcium and VITAMIN DVITAMIN D to
maximize the benefit of treatment
2007;24(12):1017-29
Drugs & Aging Drugs & Aging
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
INCREASED INCREASED
RISK OF FALLSRISK OF FALLS
2004;291:1999-2006
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
FALLS-RELATED FALLS-RELATED
FRACTURESFRACTURES
2003;18:343-51
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
HIGHER RISK FOR HIP HIGHER RISK FOR HIP
FRACTUREFRACTURE
2008;149:242-250.
VITAMIN D RECEPTORSVITAMIN D RECEPTORS
(VDRs) are known to be present in
muscle tissue.
2001 Jan;33(1):19-24.
The Histochemical JournalThe Histochemical Journal
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
AGE-RELATED MUSCLE AGE-RELATED MUSCLE
WEAKNESSWEAKNESS
1986;7:434-8
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
MUSCULOSKELETAL MUSCULOSKELETAL
PAINPAIN
2003;78:1463-70
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
CHRONIC LOW BACK PAINCHRONIC LOW BACK PAIN
2003 Jan 15;28(2):177-9
Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
INCREASED INCREASED
BODY SWAYBODY SWAY
2001;109:87-92
Lower concentrations of 25(OH)D
are associated with significant
BACK PAINBACK PAIN in older women
2008 May;56(5):785-91.
Vitamin D deficiency is now
recognized as a PANDEMIC PANDEMIC
2008 Apr;87(4):1080S-6S.
VITAMIN DVITAMIN D Reduced the
RISK OF FALLSRISK OF FALLS by More Than
20%20% Among Elderly Populations
2004;291:1999-2006
100 000 IU100 000 IU VITAMIN DVITAMIN D33 every 4
months was safe and effective in decreasing the
incidence of
OSTEOPOROTIC FRACTURESOSTEOPOROTIC FRACTURES
by by 33%33% compared with placebo
2003 Mar 1;326(7387):469.
Repletion of VITAMIN DVITAMIN D and at
the Time of Fracture May Reduce
Future Fracture Risk and
FACILITATEFACILITATE
HIP FRACTURE REPAIRHIP FRACTURE REPAIR
1999;281:1505-1511.
A single high dose of VITAMIN VITAMIN
D3D3 stimulated
FRACTURE HEALINGFRACTURE HEALING
1997;116(1-2):37-40.
CHOLECALCIFEROL CHOLECALCIFEROL (100 000 IU) is a safe, effective, and
simple way to increase calcidiol
concentrations
Vol. 87, No. 3, 688-691, March 2008.
Oral / IM Ampoule
Containing
5mg Cholecalciferol eq to 200,000 IU Cholecalciferol
Light Resistant Ampoule Packaging
Dose
1 Ampoule (200,000 IU)
every 6 months
Elderly
1/2 Ampoule (100,000 IU)
every 3 months
Thank You
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