Hypertrophic Osteodystrophy

CASE NO. 47Jessica C. Largado

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

HISTORY:

• In addition to the deformity evident in the clinical photo, this animal was lame and showed pain and warmth on palpation of the lower limb.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

LESION/S AND DESCRIPTION

•  calcification

• Hemorrhage

• Metaphyseal enlargement

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Basic disease process/es

• Inflammation

• Necrosis

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

DIAGNOSIS

• Hypertrophic osteodystrphy

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

BASIS/ BASES FOR THE DIAGNOSIS

• Historyo Animalo Breedo Ageo Specimen

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Differential diagnosis and the reasons for such.

• Panosteitis

It is a self-limiting developmental disease of young, large and giant breeds of dogs resulting in pain, lameness in one or more limbs.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

• Hypertrophic Osteopathy (HO)

It is a condition that affects long bones but is secondary to a primary thoracic or abdominal mass. The bony lesions are characterized by bilateral, symmetrical swellings affecting the distal extremities of the four limbs.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

• Etiological information

The cause of HOD is currently unknown

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Methods of transmission of the etiology and spread

Genetic component is suspected.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Other lesions present in the other organs not shown in the picture

metastatic calcification of the aorta, endocardium, lungs, and kidneys at necropsy.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Other lesions present in the other organs not shown in the picture

metastatic calcification of the aorta, endocardium, lungs, and kidneys at necropsy.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Clinical signs

• Anorexia

• Depression

• pyrexia

• weight loss.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Clinical signs

• Anorexia

• Depression

• pyrexia

• weight loss.

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Cause/s of death not necessarily euthanasia

• Cardiac failure

• Respiratory failure

• Dehydration

SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT

DANE

Cause/s of death not necessarily euthanasia

• Cardiac failure

• Respiratory failure

• Dehydration

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