Supplemental Table 1 - Home | Clinical Cancer...

Supplemental Table 1 List of genes differentially expressed in normal nasopharyngeal epithelium (N), metaplastic and displastic lesions (R), and carcinoma (T).

Parametric p-value

Permutation p-value

Geom mean

of ratios

in class 1 : N

Geom mean

of ratios

in class 2 : R

Geom mean

of ratios

in class 3 : T

Unique id

Description Clone UG cluster

Gene symbol Map

1 p < 1e-07 0 0.061 0.123 2.708 169329 secretory leukocyte protease inhibitor (antileukoproteinase)

IncytePD:2510171 Hs.251754 SLPI 20q12

2 p < 1e-07 0 0.125 0.394 1.863 163628 sodium channel, nonvoltage-gated 1 alpha

IncytePD:1453049 Hs.446415 SCNN1A 12p13

3 p < 1e-07 0 0.122 0.046 1.497 160401 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

IncytePD:2060355 Hs.73848 CEACAM6 19q13.2

4 p < 1e-07 0 0.675 1.64 5.594 165101 monoglyceride lipase IncytePD:2174920 Hs.6721 MGLL 3q21.3 5 p < 1e-07 0 0.182 0.487 0.998 166827 nei endonuclease VIII-like 1 (E.

coli) IncytePD:1926409 Hs.28355 NEIL1 15q22.33

6 p < 1e-07 0 0.194 0.339 0.915 162931 hypothetical protein FLJ22418 IncytePD:2816379 Hs.36563 FLJ22418 1p11.1 7 p < 1e-07 0 1.313 0.645 13.593 162399 S100 calcium binding protein P IncytePD:2060823 Hs.2962 S100P 4p16 8 p < 1e-07 0 0.157 1.445 2.563 169315 selenium binding protein 1 IncytePD:2591494 Hs.334841 SELENBP1 1q21-q22 9 p < 1e-07 0 0.046 0.738 1.213 160115 prominin-like 1 (mouse) IncytePD:2070568 Hs.112360 PROML1 4p15.33

10 p < 1e-07 0 0.787 2.264 3.013 167294 HRAS-like suppressor 3 IncytePD:1969263 Hs.37189 HRASLS3 11q12.3 11 p < 1e-07 0 0.292 0.539 1.493 168221 Homo sapiens cDNA FLJ13510

fis, clone PLACE1005146. IncytePD:64451 Hs.37896 2

12 p < 1e-07 0 1.816 4.162 5.231 159872 emerin (Emery-Dreifuss muscular dystrophy)

IncytePD:1901168 Hs.2985 EMD Xq28

13 p < 1e-07 0 0.096 0.237 1.251 168256 B-factor, properdin IncytePD:167371 Hs.69771 BF 6p21.3 14 p < 1e-07 0 0.112 0.566 1.205 161755 Incyte EST IncytePD:1507769 15 p < 1e-07 0 0.113 0.366 0.603 161021 zinc finger protein 204 IncytePD:1454640 Hs.8198 ZNF204 6p21.3 16 p < 1e-07 0 0.079 0.575 0.519 168604 amylase, alpha 2B; pancreatic IncytePD:254081 Hs.335493 AMY2B 1p21 17 p < 1e-07 0 0.587 1.038 0.785 168160 zinc finger protein 161 homolog

(mouse) IncytePD:2487368 Hs.156000 ZFP161 18pter-

p11.2 18 1e-07 0 0.376 0.972 1.84 167971 Meis1, myeloid ecotropic viral IncytePD:1662216 Hs.380923 MEIS3 17p11.2

integration site 1 homolog 3 (mouse)

19 1e-07 0 0.048 0.247 0.388 162648 retinoic acid receptor responder (tazarotene induced) 1

IncytePD:1982324 Hs.82547 RARRES1 3q25.32

20 1e-07 0 0.231 0.783 0.812 164495 hypothetical protein LOC283445 IncytePD:1968776 Hs.234898 LOC283445 12q24.12 21 1e-07 0 0.423 0.975 1.436 163838 family with sequence similarity 13,

member A1 IncytePD:1458366 Hs.177664 FAM13A1 4q22.1

22 1e-07 0 0.538 0.644 1.867 166314 LIM domain only 2 (rhombotin-like 1)

IncytePD:1383888 Hs.184585 LMO2 11p13

23 1e-07 0 0.023 0.095 0.53 164946 polymeric immunoglobulin receptor

IncytePD:1800114 Hs.205126 PIGR 1q31-q41

24 1e-07 0 0.283 0.959 1.196 163419 calmin (calponin-like, transmembrane)

IncytePD:1464613 Hs.406099 CLMN 14q32.2

25 1e-07 0 0.477 1.445 1.307 162175 truncated calcium binding protein IncytePD:1943110 Hs.351621 LOC51149 5q35.3 26 1e-07 0 0.481 0.977 1.168 163378 hypothetical protein

DKFZp434M0331 IncytePD:2921913 Hs.48219 DKFZp434M033 12q23.2

27 1e-07 0 0.252 0.233 1.726 166900 likely ortholog of mouse tumor necrosis-alpha-induced adipose-related protein

IncytePD:429577 Hs.44208 FLJ23153 7q21.12

28 1e-07 0 0.572 1.406 1.553 165608 REMOVED_FROM_DATABASE IncytePD:91009 29 1e-07 0 0.379 1.149 1.305 165030 galactosamine (N-acetyl)-6-sulfate

sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA)

IncytePD:2903239 Hs.159479 GALNS 16q24.3

30 1e-07 0 0.27 0.949 0.925 160243 iduronate 2-sulfatase (Hunter syndrome)

IncytePD:549290 Hs.172458 IDS Xq28

31 1e-07 0 0.401 0.79 1.775 168767 protein tyrosine phosphatase, receptor type, U

IncytePD:2941607 Hs.19718 PTPRU 1p35.3-p35.1

32 1e-07 0 0.032 0.239 1.15 166595 microseminoprotein, beta- IncytePD:3970665 33 1e-07 0 0.653 1.184 1.978 159959 Fanconi anemia, complementation

group A IncytePD:1647354

34 1e-07 0 1.376 0.457 0.853 168559 tripartite motif-containing 16 IncytePD:1996011 Hs.241305 TRIM16 17p11.2 35 1e-07 0 0.682 1.36 1.532 162892 KIAA1228 protein IncytePD:2667106 Hs.306867 KIAA1228 7q36.3 36 2e-07 0 0.261 2.62 3.645 164879 serum amyloid A4, constitutive IncytePD:86390 Hs.1955 SAA4 11p15.1-

p14 37 2e-07 0 0.67 1.763 1.345 168694 acylphosphatase 1, erythrocyte

(common) type IncytePD:1995749 Hs.18573 ACYP1 14q24.3

38 2e-07 0 0.962 2.243 2.478 162612 Rho-related BTB domain containing 1

IncytePD:2095275 Hs.15099 RHOBTB1 10q21.2

39 2e-07 0 0.097 0.26 0.515 165530 cytochrome P450, family 2, subfamily J, polypeptide 2

IncytePD:1597231 Hs.152096 CYP2J2 1p31.3-p31.2

40 2e-07 0 0.239 0.683 0.979 165148 Homo sapiens, clone IncytePD:1666815 Hs.72080 21

IMAGE:4766144, mRNA 41 2e-07 0 0.801 0.319 0.361 168279 Homo sapiens, Similar to

hypothetical protein B430208I01, clone IMAGE:5181522, mRNA, partial cds

IncytePD:1987866 Hs.106771 5

42 2e-07 0 0.072 0.298 0.917 166593 Wilms tumor associated protein IncytePD:2997479 Hs.251573 WIT-1 11p13 43 2e-07 0 1.298 1.911 5.067 167270 keratin 7 IncytePD:1649959 Hs.23881 KRT7 12q12-

q13 44 2e-07 0 0.074 0.428 0.661 166636 ESTs, Weakly similar to neuronal

thread protein [Homo sapiens] [H.sapiens]

IncytePD:2714867 Hs.436950 11

45 3e-07 0 0.41 4.837 4.942 164490 carboxylesterase 1 (monocyte/macrophage serine esterase 1)

IncytePD:1813269 Hs.76688 CES1 16q13-q22.1

46 3e-07 0 0.643 2.729 4.235 165666 ribonuclease, RNase A family, 4 IncytePD:1858905 Hs.283749 RNASE4 14q11.1 47 3e-07 0 0.449 1.314 1.636 162294 calcium channel, voltage-

dependent, beta 3 subunit IncytePD:2057662 Hs.250712 CACNB3 12q13

48 3e-07 0 0.132 0.48 0.78 160334 ATPase, Class II, type 9A IncytePD:1942046 Hs.406434 ATP9A 20q13.11-q13.2

49 4e-07 0 0.12 0.591 1.034 161500 regulatory factor X, 2 (influences HLA class II expression)

IncytePD:2674796 Hs.100007 RFX2 19p13.3-p13.2

50 4e-07 0 0.124 0.079 0.726 160357 coagulation factor III (thromboplastin, tissue factor)

IncytePD:2061594 Hs.62192 F3 1p22-p21

51 4e-07 0 0.225 0.531 0.869 160168 kinesin family member 13B IncytePD:2708596 Hs.15711 KIF13B 8p12 52 5e-07 0 0.496 0.83 0.872 160625 myeloid/lymphoid or mixed-

lineage leukemia (trithorax homolog, Drosophila); translocated to, 2

IncytePD:1887185 Hs.114765 MLLT2 4q21

53 5e-07 0 0.753 1.526 1.27 162298 hypothetical protein LOC90410 IncytePD:1552481 Hs.4187 LOC90410 17q11.1 54 5e-07 0 0.112 0.193 0.311 160654 B-cell CLL/lymphoma 6 (zinc

finger protein 51) IncytePD:1569189 Hs.155024 BCL6 3q27

55 6e-07 0 0.25 0.915 1.585 159838 aldehyde dehydrogenase 3 family, member B1

IncytePD:2610218 Hs.83155 ALDH3B1 11q13

56 6e-07 0 0.104 0.771 1.25 160072 solute carrier family 22 (organic cation transporter), member 4

IncytePD:1308162 Hs.77239 SLC22A4 5q31.1

57 6e-07 0 0.092 0.417 0.466 166685 KIAA0675 gene product IncytePD:1794725 Hs.165662 KIAA0675 3q13.12 58 7e-07 0 0.295 0.505 0.693 165716 complement component 5 receptor

1 (C5a ligand) IncytePD:1447909 Hs.2161 C5R1 19q13.3-

q13.4 59 7e-07 0 0.669 1.017 2.773 169559 E74-like factor 3 (ets domain

transcription factor, epithelial-specific )

IncytePD:1988412 Hs.166096 ELF3 1q32.2

60 7e-07 0 0.736 1.472 1.208 169562 CDC16 cell division cycle 16 homolog (S. cerevisiae)

IncytePD:1413704 Hs.1592 CDC16 13q34

61 8e-07 0 0.099 0.766 5.296 165371 trefoil factor 3 (intestinal) IncytePD:2242817 Hs.82961 TFF3 21q22.3 62 8e-07 0 0.587 1.254 1.723 164531 Homo sapiens cDNA: FLJ22050

fis, clone HEP09454. IncytePD:2868216 Hs.173705 4

63 8e-07 0 0.175 0.465 0.618 163376 ESTs IncytePD:2818878 Hs.32135 20 64 8e-07 0 0.21 0.664 0.872 163828 mucin 5, subtype B,

tracheobronchial IncytePD:1737280 Hs.102482 MUC5B 11p15

65 8e-07 0 0.327 0.686 0.7 164891 paired box gene 2 IncytePD:194662 Hs.155644 PAX2 10q22.1-q24.3

66 8e-07 0 0.114 0.079 0.535 160506 UDP glycosyltransferase 1 family, polypeptide A1

IncytePD:86450 Hs.278896 UGT1A1 2q37

67 9e-07 0 0.656 1.628 1.865 168674 Homo sapiens, clone IMAGE:5587702, mRNA

IncytePD:1964852 Hs.427683 10

68 9e-07 0 0.414 0.326 1.223 166348 epidermal growth factor receptor pathway substrate 8-related protein 1

IncytePD:1395088 Hs.28907 EPS8R1 19q13.42

69 9e-07 0 0.127 0.349 0.64 166331 Arg/Abl-interacting protein ArgBP2

IncytePD:1495766 Hs.379795 ARGBP2 4q35.1

70 9e-07 0 1.011 2.238 2.34 169526 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

IncytePD:1236828 Hs.332173 TLE2 19p13.3

71 9e-07 0 0.103 0.574 0.967 169644 hypothetical protein MGC27085 IncytePD:1256859 Hs.120277 MGC27085 3q26.31 72 9e-07 0 0.01 0.039 0.431 161792 tetraspan 1 IncytePD:2989680 Hs.38972 TSPAN-1 1p33 73 1e-06 0 0.17 0.872 1.348 163423 Incyte EST IncytePD:2279991 74 1e-06 0 0.238 0.485 0.47 159850 Homo sapiens cDNA FLJ34315

fis, clone FEBRA2008341. IncytePD:1734634 Hs.376655 14

75 1e-06 0 0.3 0.757 1.002 166527 hypothetical protein FLJ13942 IncytePD:2041712 Hs.20537 FLJ13942 6q22.31 76 1e-06 0 0.644 1.523 3.163 167091 epidermal growth factor receptor

pathway substrate 8 IncytePD:438438 Hs.2132 EPS8 12q23-

q24 77 1e-06 0 1.325 1.701 4.492 162505 keratin 7 IncytePD:1962141 Hs.23881 KRT7 12q12-

q13 78 1e-06 0 0.431 1.599 3.091 165457 solute carrier family 27 (fatty acid

transporter), member 2 IncytePD:2658782 Hs.11729 SLC27A2 15q21.2

79 1.1e-06 0 0.081 0.357 0.991 168850 dynein, axonemal, light intermediate polypeptide 1

IncytePD:1998792 Hs.406050 DNALI1 1p35.1

80 1.2e-06 0 0.163 0.561 0.82 169048 ESTs IncytePD:4003773 Hs.131511 2 81 1.2e-06 0 0.379 0.649 0.829 163234 Incyte EST IncytePD:2243769 82 1.2e-06 0 0.212 0.357 2.962 160726 mucin 1, transmembrane IncytePD:2957567 Hs.89603 MUC1 1q21 83 1.3e-06 0 0.389 0.55 1.119 163443 ESTs IncytePD:2136337 Hs.110044 9 84 1.3e-06 0 1.038 2.034 2.222 169319 calponin 1, basic, smooth muscle IncytePD:2696735 Hs.21223 CNN1 19p13.2-

85 1.4e-06 0 0.208 0.23 0.648 160543 Rho GTPase-activating protein IncytePD:2283906 Hs.111138 RICS 11q24-q25

86 1.4e-06 0 0.137 0.72 1.446 168057 hypothetical protein FLJ22167 IncytePD:2571363 Hs.6853 FLJ22167 16q22.3 87 1.4e-06 0 0.303 0.705 0.67 166070 kallikrein B, plasma (Fletcher

factor) 1 IncytePD:2021730 Hs.1901 KLKB1 4q34-q35

88 1.4e-06 0 1.015 1.799 2.67 168487 two-pore channel 1, homolog IncytePD:589453 Hs.26440 KIAA1169 12q24.21 89 1.5e-06 0 0.61 2.333 2.879 166320 transforming growth factor, beta

receptor III (betaglycan, 300kDa) IncytePD:1443766 Hs.342874 TGFBR3 1p33-p32

90 1.6e-06 0 0.984 0.821 1.719 159793 inositol polyphosphate-4-phosphatase, type II, 105kDa

IncytePD:3032739 Hs.153687 INPP4B 4q31.1

91 1.6e-06 0 0.207 0.463 0.721 160541 lipidosin IncytePD:1996309 Hs.277543 BG1 15q23-q24

92 1.7e-06 0 0.5 0.688 2.521 163859 anterior gradient 2 homolog (Xenepus laevis)

IncytePD:1998428 Hs.413945 AGR2 7p21.3

93 1.7e-06 0 0.225 0.535 0.603 167754 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 926491.

IncytePD:1506962 Hs.98401 19

94 1.8e-06 0 1.742 3.49 7.177 164578 diaphorase (NADH/NADPH) (cytochrome b-5 reductase)

IncytePD:2637222

95 1.8e-06 0 1.849 5.058 8.219 159920 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6

IncytePD:1904994 Hs.41072 SERPINB6 6p25

96 1.8e-06 0 0.32 0.561 0.537 168531 A kinase (PRKA) anchor protein (yotiao) 9

IncytePD:997782 Hs.58103 AKAP9 7q21-q22

97 1.8e-06 0 0.229 0.598 1.079 166104 inhibin, beta B (activin AB beta polypeptide)

IncytePD:1504993 Hs.1735 INHBB 2cen-q13

98 1.9e-06 0 0.048 0.309 0.671 167328 Ras-related associated with diabetes

IncytePD:1538224 Hs.1027 RRAD 16q22

99 2e-06 0 0.456 1.307 1.636 166777 hypothetical protein FLJ21827 IncytePD:261809 Hs.334360 FLJ21827 11q23.3 100 2.3e-06 0 0.206 0.508 0.646 165971 histidine decarboxylase IncytePD:1998060 Hs.1481 HDC 15q21-

q22 101 2.3e-06 0 0.565 1.201 1.232 169235 numb homolog (Drosophila) IncytePD:1879023 Hs.78890 NUMB 14q24.3 102 2.4e-06 0 1.96 1.994 4.405 165557 FK506 binding protein 1B, 12.6

kDa IncytePD:1288118 Hs.77643 FKBP1B 2p24.1

103 2.5e-06 0 3.501 1.864 1.306 162033 kinesin family member 14 IncytePD:4511928 Hs.3104 KIF14 1pter-q31.3

104 2.5e-06 0 1.02 0.545 0.485 165593 transmembrane 7 superfamily member 1 (upregulated in kidney)

IncytePD:830684 Hs.15791 TM7SF1 1q42-q43

105 2.6e-06 0 0.317 0.636 1.071 168607 B/K protein IncytePD:1922038 Hs.26971 LOC51760 16p13.11 106 2.6e-06 0 0.726 1.156 2.525 169159 KIAA0089 protein IncytePD:1803418 Hs.82432 KIAA0089 3p22.3 107 2.6e-06 0 0.653 0.702 1.283 163467 hypothetical protein BC010682 IncytePD:1493357 Hs.4896 LOC90550 10q22.2

108 2.7e-06 0 0.327 0.777 0.94 160277 chromosome 14 open reading frame 79

IncytePD:2056424 Hs.27183 C14orf79 14q32.33

109 2.9e-06 0 5.987 3.491 2.185 166182 exonuclease 1 IncytePD:4385292 Hs.47504 EXO1 1q42-q43 110 3.1e-06 0 0.269 0.504 1.25 160146 myosin ID IncytePD:1556011 Hs.39871 MYO1D 17q11-

q12 111 3.1e-06 0 1.122 0.739 0.594 165206 syntaxin 6 IncytePD:2748585 Hs.157144 STX6 1q24.3 112 3.2e-06 0 1.291 0.597 0.657 160635 v-ral simian leukemia viral

oncogene homolog A (ras related) IncytePD:1981716 Hs.6906 RALA 7p22-p15

113 3.3e-06 0 0.247 0.405 1.132 160285 Meis1, myeloid ecotropic viral integration site 1 homolog (mouse)

IncytePD:2310087 Hs.170177 MEIS1 2p14-p13

114 3.4e-06 0 2.515 4.644 9.218 167401 microphthalmia-associated transcription factor

IncytePD:3484440 Hs.166017 MITF 3p14.1-p12.3

115 3.5e-06 0 0.592 1.081 1.137 164635 DKFZP586P0123 protein IncytePD:1923483 Hs.376803 DKFZP586P012 11q13.3 116 3.6e-06 0 0.939 2.121 1.959 165730 mannose-6-phosphate receptor

(cation dependent) IncytePD:1489979 Hs.134084 M6PR 12p13

117 3.9e-06 0 0.459 0.911 0.883 164826 Homo sapiens cDNA FLJ30048 fis, clone ADRGL1000018.

IncytePD:2466668 Hs.238956 17

118 3.9e-06 0 0.436 0.796 0.802 164177 Homo sapiens, Similar to hypothetical protein FLJ13639, clone IMAGE:4310637, mRNA

IncytePD:2372541 Hs.390401 13

119 4e-06 0 0.673 1.672 1.669 163281 hypothetical protein FLJ20345 IncytePD:1495247 Hs.20558 FLJ20345 17q23.2 120 4.1e-06 0 0.253 0.569 0.685 166597 collagen, type VIII, alpha 1 IncytePD:3118643 Hs.114599 COL8A1 3q12-

q13.1 121 4.1e-06 0 0.111 0.418 0.613 165478 Homo sapiens cDNA FLJ11375

fis, clone HEMBA1000411, weakly similar to ANKYRIN.

IncytePD:1850249 Hs.352591 10

122 4.3e-06 0 0.055 0.536 0.443 159964 B-cell CLL/lymphoma 3 IncytePD:1867294 Hs.31210 BCL3 19q13.1-q13.2

123 4.4e-06 0 0.633 0.987 0.743 160700 phosphatidylinositol glycan, class F IncytePD:1557568 Hs.426142 PIGF 2p21-p16 124 4.4e-06 0 0.101 0.462 0.664 165615 sperm associated antigen 8 IncytePD:1731716 Hs.256747 SPAG8 9p13.3 125 4.4e-06 0 0.348 0.813 0.634 162195 ESTs, Weakly similar to

hypothetical protein FLJ20489 [Homo sapiens] [H.sapiens]

IncytePD:777175 Hs.348501 8

126 4.7e-06 0 0.484 1.005 0.915 169304 hypothetical protein GL012 IncytePD:1943427 Hs.21379 GL012 9q34.11 127 4.8e-06 0 0.532 0.91 1.633 165764 dihydropyrimidinase-like 3 IncytePD:1403636 Hs.74566 DPYSL3 5q32 128 4.9e-06 0 0.228 0.525 0.531 167976 ESTs, Weakly similar to

ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome; Ubiquitously transcribed TPR gene on Y chromosome [Homo sapiens]

IncytePD:2610364 Hs.371676 17

[H.sapiens] 129 4.9e-06 0 0.308 0.659 0.488 162092 E1A binding protein p400 IncytePD:1967172 Hs.306094 EP400 12q24.33 130 4.9e-06 0 0.231 0.651 0.762 166561 hypothetical protein RP4-622L5 IncytePD:3223070 Hs.272299 RP4-622L5 1p36.11-

p34.2 131 5e-06 0 0.314 0.605 0.607 168797 hypothetical protein LOC284001 IncytePD:2751505 Hs.122075 LOC284001 17q25.3 132 5.1e-06 0 0.224 0.494 0.628 165297 ESTs IncytePD:2959963 Hs.189955 7 133 5.2e-06 0 2.086 0.535 1.864 163591 Incyte EST IncytePD:1260330 134 5.2e-06 0 0.502 1.699 1.535 160723 Homo sapiens clone 24790 mRNA

sequence IncytePD:866608 Hs.13431 12

135 5.6e-06 0 0.435 0.635 1.059 166477 ESTs IncytePD:1984918 Hs.165795 14 136 5.7e-06 0 0.371 0.73 0.727 160326 D-aspartate oxidase IncytePD:464406 Hs.174441 DDO 6q21 137 5.8e-06 0 0.465 3.116 2.76 162194 complement component 4A IncytePD:1996090 Hs.170250 C4A 6p21.3 138 6e-06 0 0.374 2.858 2.524 163985 melanoma inhibitory activity IncytePD:1911332 Hs.279651 MIA 19q13.32-

q13.33 139 6e-06 0 0.202 0.7 1.318 163549 ARF protein IncytePD:1697490 Hs.264509 LOC51326 17q21.31 140 6e-06 0 7.405 4.341 3.256 167168 discs, large homolog 7

(Drosophila) IncytePD:1970111 Hs.77695 DLG7 14q22.1

141 6.2e-06 0 0.808 1.368 1.384 168378 MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein

IncytePD:789491 Hs.168481 MCM3AP 21q22.3

142 6.4e-06 0 0.388 1.069 0.988 160679 TBP-interacting protein IncytePD:1842689 Hs.154740 TIP120B 3p25.1 143 6.4e-06 0 0.841 1.545 3.578 168362 serum-inducible kinase IncytePD:1255087 Hs.3838 SNK 5q12.1-

q13.2 144 6.4e-06 0 0.13 0.312 0.243 163465 Homo sapiens mRNA; cDNA

DKFZp762N156 (from clone DKFZp762N156)

IncytePD:695016 Hs.194397 7

145 6.5e-06 0 0.721 0.191 0.246 161050 claudin 1 IncytePD:2795896 Hs.7327 CLDN1 3q28-q29 146 6.6e-06 0 0.059 0.255 0.467 164669 hypothetical protein FLJ10466 IncytePD:1336835 Hs.121073 FLJ10466 6p12.1 147 6.7e-06 0 1.335 2.051 3.001 168486 tropomyosin 4 IncytePD:1996511 Hs.250641 TPM4 19p13.1 148 6.8e-06 0 0.279 0.598 1.293 165213 tripartite motif-containing 2 IncytePD:1267176 Hs.12372 TRIM2 4q31.23 149 6.8e-06 0 0.185 0.529 0.75 161240 KIAA0703 gene product IncytePD:2791383 Hs.6168 KIAA0703 16q23.3 150 6.9e-06 0 0.374 1.095 1.5 166919 axin 2 (conductin, axil) IncytePD:2359588 Hs.127337 AXIN2 17q23-

q24 151 7.1e-06 0 0.494 0.55 1.09 164019 UDP-N-acetyl-alpha-D-

galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)

IncytePD:2815133 Hs.271923 GALNT4 12q21.3-q22

152 7.2e-06 0 1.94 1.775 8.351 169308 Homo sapiens, clone IMAGE:4471726, mRNA

IncytePD:899118 Hs.288660 12

153 7.3e-06 0 0.347 0.903 0.938 162998 oxysterol binding protein-like 5 IncytePD:2021590 Hs.112034 OSBPL5 11p15.4 154 7.4e-06 0 0.293 0.883 0.995 167251 zinc finger protein 91 homolog IncytePD:2904011 Hs.46366 ZFP91 11q12

(mouse) 155 7.9e-06 0 0.572 0.623 1.64 166137 KIAA0790 protein IncytePD:1722691 Hs.12002 KIAA0790 6q24.3 156 8.1e-06 0 0.169 0.084 0.923 160894 tumor-associated calcium signal

transducer 2 IncytePD:1600421 Hs.23582 TACSTD2 1p32-p31

157 8.3e-06 0 0.237 0.613 1.162 166246 mutated in colorectal cancers IncytePD:1599488 Hs.1345 MCC 5q21-q22 158 8.4e-06 0 0.27 0.76 1.052 168967 KIAA1244 protein IncytePD:1751692 Hs.194408 KIAA1244 6q23.3 159 8.8e-06 0 0.157 0.757 1.546 164829 B7 protein IncytePD:1215389 Hs.155586 B7 12p13 160 8.8e-06 0 0.374 0.551 0.866 166810 ESTs IncytePD:640177 Hs.110334 4 161 9.1e-06 0 0.519 0.902 0.844 161402 bromodomain containing 8 IncytePD:2634206 Hs.5464 BRD8 5q31 162 9.1e-06 5e-04 0.183 0.244 0.811 169569 spermidine/spermine N1-

acetyltransferase IncytePD:63038 Hs.28491 SAT Xp22.1

163 9.9e-06 0 0.747 1.77 1.35 167476 Homo sapiens cDNA FLJ30301 fis, clone BRACE2003217.

IncytePD:1399368 Hs.285728 2

164 1.02e-05 0 2.013 1.973 1.089 162747 thymopoietin IncytePD:2289176 Hs.406660 TMPO 12q22 165 1.05e-05 0 0.322 0.85 2.339 168336 claudin 10 IncytePD:958923 Hs.26126 CLDN10 13q31-

q34 166 1.07e-05 0 0.738 2.268 1.632 164746 SWI/SNF related, matrix

associated, actin dependent regulator of chromatin, subfamily d, member 3

IncytePD:1888940 Hs.71622 SMARCD3 7q35-q36

167 1.1e-05 0 0.148 0.404 0.637 159957 calcium channel, voltage-dependent, gamma subunit 3

IncytePD:1414565 Hs.7235 CACNG3 16p12-p13.1

168 1.12e-05 0 0.82 1.489 1.301 163386 bromodomain containing 8 IncytePD:2992892 Hs.5464 BRD8 5q31 169 1.13e-05 0 0.306 0.539 0.697 164511 synaptopodin IncytePD:1923572 Hs.5307 KIAA1029 5q33.1 170 1.2e-05 0 0.5 1.016 1.267 159780 multiple PDZ domain protein IncytePD:1601609 Hs.169378 MPDZ 9p24-p22 171 1.22e-05 0 0.267 0.302 0.757 166468 dihydropyrimidine dehydrogenase IncytePD:1485479 Hs.1602 DPYD 1p22 172 1.23e-05 0 0.568 0.953 0.949 169563 zinc finger protein 103 homolog

(mouse) IncytePD:1843290 Hs.155968 ZFP103 2p11.2

173 1.26e-05 0 0.617 1.242 1.295 162008 growth arrest-specific 8 IncytePD:3687253 Hs.54877 GAS8 16q24.3 174 1.27e-05 0 0.57 1.142 0.768 160699 RAB28, member RAS oncogene

family IncytePD:1457948 Hs.404189 RAB28 4p16.1

175 1.27e-05 0 0.2 0.413 0.613 163235 FLJ00005 protein IncytePD:1368493 Hs.367690 FLJ00005 15q22.33 176 1.27e-05 0 4.58 4.97 2.124 167789 syndecan 2 (heparan sulfate

proteoglycan 1, cell surface-associated, fibroglycan)

IncytePD:1782172 Hs.1501 SDC2 8q22-q23

177 1.29e-05 0 0.985 0.912 2.358 163772 calpastatin IncytePD:1453748 Hs.359682 CAST 5q15-q21 178 1.31e-05 0 0.403 0.703 0.957 162528 Homo sapiens clone 23736 mRNA

sequence IncytePD:962043 Hs.7888 2

179 1.32e-05 0 0.838 1.897 1.113 168959 hypothetical protein FLJ21016 IncytePD:1447393 Hs.289069 FLJ21016 1q42.12 180 1.33e-05 0 0.49 1.516 1.321 163704 nei like 2 (E. coli) IncytePD:2025662 Hs.293818 NEIL2 8 181 1.35e-05 0 0.67 2.049 2.178 166554 echinoderm microtubule associated IncytePD:1482116 Hs.12451 EML1 14q32

protein like 1 182 1.37e-05 0 0.361 0.574 0.666 163513 KIAA1272 protein IncytePD:1540157 Hs.15978 KIAA1272 20p11.22 183 1.38e-05 0 0.048 0.286 0.604 162545 sperm associated antigen 6 IncytePD:2360811 Hs.158213 SPAG6 10p12.2 184 1.42e-05 0 0.445 1.479 1.417 162146 KIAA0590 gene product IncytePD:1996021 Hs.111862 KIAA0590 16p13.3 185 1.47e-05 0 2.364 2.182 1.249 162797 TED protein IncytePD:2409533 Hs.87619 TED Xq13.1 186 1.49e-05 0 0.668 1.418 3.739 169417 ceruloplasmin (ferroxidase) IncytePD:1982416 Hs.296634 CP 3q23-q25 187 1.5e-05 0 1.244 2.189 3.54 160847 microphthalmia-associated

transcription factor IncytePD:1749130 Hs.166017 MITF 3p14.1-

p12.3 188 1.56e-05 0 0.153 0.871 0.955 167355 solute carrier family 26, member 4 IncytePD:3407861 Hs.159275 SLC26A4 7q31 189 1.56e-05 0 0.58 1.422 1.634 169649 KIAA0397 gene product IncytePD:1001871 Hs.7416 KIAA0397 17p13.3 190 1.58e-05 0 1.976 0.393 1.696 163438 kallikrein 6 (neurosin, zyme) IncytePD:1480159 Hs.79361 KLK6 19q13.3 191 1.59e-05 0 1.009 2.014 2.023 163456 phytanoyl-CoA hydroxylase

(Refsum disease) IncytePD:4073867 Hs.172887 PHYH 10pter-

p11.2 192 1.6e-05 0 0.086 0.295 0.632 163509 Hermansky-Pudlak syndrome 3 IncytePD:604991 Hs.282804 HPS3 3q24 193 1.6e-05 0 0.924 1.58 2.563 164719 putative ankyrin-repeat containing

protein IncytePD:1689764 Hs.4996 DKFZP564D166 17q23.3

194 1.63e-05 0 0.536 1.168 1.336 162256 Human DNA sequence from clone 742C19 on chromosome 22q12.3-13.1. Contains a pseudogene similar to Cytochrome C Oxidase Polypeptide VB and (parts of) up to four novel genes, two with homology to Phorbolin genes and one a novel Chro

IncytePD:1841459

195 1.66e-05 0 0.984 1.881 2.912 163651 adenylyl cyclase-associated protein 2

IncytePD:999366 Hs.296341 CAP2 6p22.3

196 1.66e-05 0 0.334 0.236 0.938 168892 LIM domain only 7 IncytePD:1832584 Hs.5978 LMO7 13q21.33 197 1.73e-05 0 1.226 0.751 0.707 168272 T cell receptor delta locus IncytePD:2556177 Hs.2014 TRD@ 14q11.2 198 1.76e-05 0 0.314 0.895 0.906 168367 DKFZP586A0522 protein IncytePD:1965049 Hs.288771 DKFZP586A052 12q13.12 199 1.77e-05 0 0.019 0.016 0.309 159789 serine (or cysteine) proteinase

inhibitor, clade B (ovalbumin), member 3

IncytePD:2795874 Hs.227948 SERPINB3 18q21.3

200 1.78e-05 0 0.67 0.99 1.192 169280 Homo sapiens cDNA FLJ39316 fis, clone OCBBF2014052.

IncytePD:2619 Hs.343787 16

201 1.8e-05 0 0.478 1.393 1.197 167987 ectonucleoside triphosphate diphosphohydrolase 1

IncytePD:1672749 Hs.205353 ENTPD1 10q24

202 1.85e-05 0 0.086 0.518 0.407 160717 benzodiazapine receptor (peripheral) associated protein 1

IncytePD:1865225 Hs.112499 BZRAP1 17q22-q23

203 1.86e-05 0 0.196 0.491 0.592 164185 hypothetical protein FLJ10300 IncytePD:3881016 Hs.42233 FLJ10300 7q36.3 204 1.87e-05 0 0.094 0.324 0.38 165143 hypothetical protein FLJ20535 IncytePD:4044967 Hs.183362 FLJ20535 11q23.2 205 1.88e-05 0 0.147 0.537 0.411 167082 Homo sapiens colon cancer antigen IncytePD:275494 Hs.160881 6

NY-CO-45 mRNA, partial cds 206 1.88e-05 0 0.214 0.485 0.676 164963 cystic fibrosis transmembrane

conductance regulator, ATP-binding cassette (sub-family C, member 7)

IncytePD:1285503 Hs.426266 CFTR 7q31.2

207 1.89e-05 0 0.431 1.263 1.345 169138 PTH-responsive osteosarcoma B1 protein

IncytePD:15650 Hs.79340 B1 7p14

208 1.9e-05 0 0.355 1.218 1.081 168606 Duffy blood group IncytePD:1987335 Hs.183 FY 1q21-q22 209 1.97e-05 0 0.958 2.411 2.63 168996 Bernardinelli-Seip congenital

lipodystrophy 2 (seipin) IncytePD:553371 Hs.293981 BSCL2 11q12-

q13.5 210 2.01e-05 0 0.246 0.61 1.063 166877 Hypothetical 55.1 kDa protein

F09G8.5 in chromosome III IncytePD:2285109 Hs.125201 LOC220074 11q13.2

211 2.02e-05 0 0.205 0.815 0.705 166256 Homo sapiens cDNA FLJ20115 fis, clone COL05594

IncytePD:2716261

212 2.03e-05 0 0.599 1.345 0.927 163707 PHD protein Jade-1 IncytePD:937508 Hs.238246 Jade-1 4q26-q27 213 2.17e-05 0 1.616 1.824 1.022 168296 acidic (leucine-rich) nuclear

phosphoprotein 32 family, member A

IncytePD:1994721 Hs.285013 ANP32A 15q22.3-q23

214 2.2e-05 0 0.507 0.815 0.864 169245 myotubular myopathy 1 IncytePD:1560906 Hs.75302 MTM1 Xq28 215 2.21e-05 0 0.532 1.326 1.183 164945 retinitis pigmentosa GTPase

regulator IncytePD:311313 Hs.153614 RPGR Xp11.4

216 2.25e-05 5e-04 1.959 2.137 4.826 164646 galactose-4-epimerase, UDP- IncytePD:1807294 Hs.76057 GALE 1p36-p35 217 2.31e-05 0 0.328 0.596 0.979 162921 hypothetical protein FLJ32029 IncytePD:2929840 Hs.26612 FLJ32029 11q13.3 218 2.35e-05 0 0.228 0.549 0.974 163848 oxysterol binding protein-like 6 IncytePD:2245743 Hs.318775 OSBPL6 2q31-

q32.1 219 2.46e-05 5e-04 0.288 0.24 0.917 166853 EphA2 IncytePD:1958394 Hs.171596 EPHA2 1p36 220 2.49e-05 0 0.539 0.885 0.746 165486 component of oligomeric golgi

complex 8 IncytePD:2462127 Hs.224179 COG8 16q22.1

221 2.55e-05 5e-04 0.729 1.023 1.836 165059 v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)

IncytePD:1726407 Hs.348024 RALB 2cen-q13

222 2.6e-05 0 0.021 0.215 0.544 167527 forkhead box J1 IncytePD:2867091 Hs.93974 FOXJ1 17q22-17q25

223 2.64e-05 0 0.275 0.917 1.109 160377 oxytocin receptor IncytePD:640605 Hs.2820 OXTR 3p25 224 2.77e-05 0 0.407 1.1 1.35 161218 phosphodiesterase 8B IncytePD:1684787 Hs.78106 PDE8B 5q13.2 225 2.79e-05 0 0.308 0.594 0.528 161673 Human clone CE29 7.2

(CAC)n/(GTG)n repeat-containing mRNA.

IncytePD:3712928 Hs.133065 2

226 2.79e-05 0 0.527 0.965 1.065 166495 zinc finger protein 135 (clone pHZ-17)

IncytePD:3176222 Hs.374293 ZNF135 19q13.4

227 2.81e-05 0 0.255 0.604 0.654 166754 hypothetical protein DJ667H12.2 IncytePD:1757834 Hs.21068 DJ667H12.2 1q32.1-

q41 228 2.87e-05 0 0.557 0.92 0.975 165151 Homo sapiens cDNA FLJ33989

fis, clone DFNES2006944. IncytePD:3282436 Hs.118421 4

229 2.89e-05 0 2.269 1.105 0.731 166838 cyclin D2 IncytePD:1618422 Hs.75586 CCND2 12p13 230 2.98e-05 0 0.418 0.132 0.829 163544 defensin, beta 1 IncytePD:2912830 Hs.32949 DEFB1 8p23.2-

p23.1 231 2.99e-05 0 1.373 3.274 6.143 169321 clusterin (complement lysis

inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)

IncytePD:2966620 Hs.75106 CLU 8p21-p12

232 3.04e-05 0 0.667 0.397 1.01 166392 nuclear receptor coactivator 6 interacting protein

IncytePD:2239295 Hs.179909 NCOA6IP 8q11

233 3.06e-05 0 0.662 2.3 2.372 165183 cysteine-rich protein 2 IncytePD:2672064 Hs.70327 CRIP2 14q32.3 234 3.09e-05 5e-04 0.796 0.471 4.026 163959 ESTs, Weakly similar to CGHU7L

collagen alpha 1(III) chain precursor - human [H.sapiens]

IncytePD:938641 Hs.355747 1

235 3.17e-05 0 0.134 0.527 1.62 160220 aldehyde dehydrogenase 1 family, member A1

IncytePD:96425 Hs.76392 ALDH1A1 9q21.13

236 3.27e-05 0 0.107 0.334 0.544 161341 vanin 1 IncytePD:3843507 Hs.12114 VNN1 6q23-q24 237 3.36e-05 0 0.353 0.847 1.069 162297 hypothetical protein FLJ20375 IncytePD:995821 Hs.274251 FLJ20375 9p21 238 3.45e-05 0 0.134 0.275 0.505 162984 cytidine monophosphate-N-

acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase)

IncytePD:2488807 Hs.24697 CMAH 6p21.32

239 3.47e-05 0 1.361 0.516 0.547 169575 fibromodulin IncytePD:1999120 Hs.230 FMOD 1q32 240 3.54e-05 0 1.547 0.651 0.619 163006 frizzled homolog 7 (Drosophila) IncytePD:2736837 Hs.173859 FZD7 2q33 241 3.59e-05 0 1.409 1.528 0.837 164402 lamin B receptor IncytePD:1803808 Hs.152931 LBR 1q42.1 242 3.6e-05 0 0.292 0.58 1.012 164496 KIAA0284 protein IncytePD:1890138 Hs.182536 KIAA0284 14q32.33 243 3.66e-05 0 0.66 1.16 1.161 166926 X-prolyl aminopeptidase

(aminopeptidase P) 1, soluble IncytePD:1616328 Hs.284202 XPNPEP1 10q25.3

244 3.69e-05 0 0.062 0.644 0.483 159916 lactotransferrin IncytePD:1861911 Hs.105938 LTF 3q21-q23 245 3.7e-05 0 2.11 5.258 6.128 166366 macrophage stimulating,

pseudogene 9 IncytePD:1379063 Hs.278657 MSTP9 1p36.13

246 3.85e-05 5e-04 0.59 0.324 1.265 159972 pre-B-cell colony-enhancing factor IncytePD:1641590 Hs.239138 PBEF 7q22.1 247 3.96e-05 0 1.102 1.332 0.791 168466 high mobility group nucleosomal

binding domain 4 IncytePD:1748670 Hs.236774 HMGN4 6p21.3

248 4.09e-05 5e-04 3.183 4.287 7.102 162705 loss of heterozygosity, 11, chromosomal region 2, gene A

IncytePD:2760753 Hs.152944 LOH11CR2A 11q23

IncytePD:566860 Hs.24792 C12orf5 12p13.3

250 4.33e-05 0 0.684 1.138 1.015 166356 hypothetical protein LOC125150 IncytePD:2556708 Hs.379903 LOC125150 17p11.2 251 4.53e-05 0 0.554 0.868 1.312 160920 meningioma expressed antigen 6

(coiled-coil proline-rich) IncytePD:1721320 Hs.117242 MGEA6 14q

252 4.62e-05 0 0.05 0.332 0.657 162045 non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)

IncytePD:2799253 Hs.72050 NME5 5q31

253 4.69e-05 0 0.465 1.275 1.07 160052 rTS beta protein IncytePD:1808980 Hs.180433 HSRTSBETA 18p11.32 254 4.93e-05 0 0.19 0.451 0.656 169399 pregnancy-zone protein IncytePD:279949 Hs.74094 PZP 12p13-

p12.2 255 5e-05 0 0.208 0.539 0.985 163597 hypothetical protein FLJ20366 IncytePD:1755193 Hs.8358 FLJ20366 8q23.2 256 5.02e-05 0 0.875 0.476 0.378 165241 hypothetical protein LOC283658 IncytePD:1236752 Hs.87194 LOC283658 15q21.1 257 5.15e-05 0 0.198 0.561 0.447 166837 ESTs IncytePD:2359527 Hs.279482 2 258 5.16e-05 0 1.032 4.785 6.908 163726 complement component 3 IncytePD:1513989 Hs.284394 C3 19p13.3-

p13.2 259 5.17e-05 0 0.266 0.71 0.823 162518 KIAA0445 gene product IncytePD:2119925 Hs.301065 KIAA0445 1pter-

p36.11 260 5.19e-05 0 4.641 2.894 2.16 169184 centromere protein F, 350/400ka

(mitosin) IncytePD:485111 Hs.77204 CENPF 1q32-q41

261 5.34e-05 0 0.223 0.697 0.658 160618 Probe hTg737 (polycystic kidney disease, autosomal recessive)

IncytePD:1663493 Hs.2291 TG737 13q12.1

262 5.4e-05 0 0.527 1.241 0.97 162169 cold inducible RNA binding protein

IncytePD:180164 Hs.119475 CIRBP 19p13.3

263 5.45e-05 0 0.256 0.374 1.053 169297 protein tyrosine phosphatase, receptor-type, Z polypeptide 1

IncytePD:1615557 Hs.78867 PTPRZ1 7q31.3

264 5.46e-05 0 0.592 0.779 1.628 160680 apolipoprotein D IncytePD:3948420 Hs.75736 APOD 3q26.2-qter

266 5.71e-05 0 1.213 1.836 1.812 162500 glycosyltransferase AD-017 IncytePD:1924806 Hs.283737 AD-017 3p21.31 267 5.96e-05 0 0.75 1.481 1.469 168608 receptor (calcitonin) activity

modifying protein 2 IncytePD:1988044 Hs.155106 RAMP2 17q12-

q21.1 268 5.98e-05 0 0.097 0.355 0.491 162422 EBNA1 binding protein 2 IncytePD:5508378 Hs.346868 EBNA1BP2 1p35-p33 269 6.02e-05 0 1.556 1.07 0.814 162906 hypothetical protein FLJ11294 IncytePD:2070313 Hs.107000 FLJ11294 2q14.3 270 6.07e-05 0 0.375 1.995 3.9 164418 connective tissue growth factor IncytePD:1674454 Hs.75511 CTGF 6q23.1 271 6.07e-05 0 0.698 0.843 0.521 162828 nucleoporin-like protein 1 IncytePD:1922694 Hs.168352 NLP_1 7p15 272 6.13e-05 0 0.575 0.834 1.619 165160 synaptotagmin-like 2 IncytePD:1415307 Hs.92254 SYTL2 11q14 273 6.14e-05 5e-04 0.545 0.438 1.483 162552 Kruppel-like factor 4 (gut) IncytePD:1962235 Hs.356370 KLF4 9q31 274 6.23e-05 0 0.277 0.55 0.523 163349 Homo sapiens cDNA FLJ30016

fis, clone 3NB692000429. IncytePD:1570161 Hs.14931 10

275 6.31e-05 0 0.434 0.771 0.663 164169 SECIS binding protein 2 IncytePD:1877743 Hs.288141 SBP2 9q22.1 276 6.31e-05 0 0.528 1.224 1.282 163044 Homo sapiens cDNA FLJ36248 IncytePD:2705256 Hs.41352 3

fis, clone THYMU2001989. 277 6.32e-05 0 0.855 1.599 1.858 167899 hypothetical protein FLJ20477 IncytePD:2313030 Hs.26994 FLJ20477 1p35.3 278 6.33e-05 0 0.438 0.693 0.565 161560 Incyte EST IncytePD:2160566 279 6.34e-05 0 0.306 0.741 1.148 165146 chromosome 9 open reading frame

9 IncytePD:2241912 Hs.62595 C9orf9 9q34

280 6.35e-05 0 0.565 0.972 0.743 166609 hypothetical protein FLJ20003 IncytePD:1921914 Hs.258798 FLJ20003 10q26.13 281 6.4e-05 0 0.222 0.379 0.916 169070 serine/threonine kinase with Dbl-

and pleckstrin homology domains IncytePD:2285303 Hs.162189 TRAD 3q21.2

282 6.42e-05 0 1.965 3.333 2.705 161058 multiple endocrine neoplasia I IncytePD:1693847 Hs.423348 MEN1 11q13 283 6.45e-05 0 0.741 1.303 1.413 169237 lecithin-cholesterol acyltransferase IncytePD:2395357 284 6.49e-05 0 0.84 1.875 1.043 168879 ESTs, Weakly similar to

IncytePD:1451756 Hs.23272 6

285 6.65e-05 0 0.899 1.135 0.663 162949 RNA binding motif protein 15 IncytePD:1379395 Hs.46670 RBM15 1p13 286 6.71e-05 0 1.115 0.624 0.569 168455 Homo sapiens cDNA FLJ13427

287 6.74e-05 0 1.046 0.489 0.794 167876 ESTs IncytePD:1888036 Hs.427773 2 288 6.84e-05 0 0.146 0.487 0.716 163656 ESTs IncytePD:2360418 Hs.432503 1 289 7.02e-05 0 3.66 0.344 4.471 168350 serine (or cysteine) proteinase

inhibitor, clade B (ovalbumin), member 2

290 7.05e-05 0 0.475 1.071 0.77 166954 hypothetical protein FLJ10081 IncytePD:1215329 Hs.7871 FLJ10081 2p12-p11.2

291 7.06e-05 5e-04 0.429 0.71 0.507 163060 Homo sapiens mRNA; cDNA DKFZp313P0917 (from clone DKFZp313P0917)

IncytePD:1753040 Hs.322851 9

292 7.08e-05 0 1.75 1.61 1.114 164934 KIAA1340 protein IncytePD:2917963 Hs.51743 KIAA1340 12p11.23 293 7.25e-05 0 0.316 0.173 0.793 161148 kallikrein 10 IncytePD:2851003 Hs.69423 KLK10 19q13.3-

q13.4 294 7.27e-05 0 3.06 2.074 1.555 163116 chromosome 1 open reading frame

295 7.29e-05 0 2.031 1.086 0.946 167473 cyclin B1 IncytePD:2877029 Hs.23960 CCNB1 5q12 296 7.35e-05 0 0.301 0.678 0.994 165609 tetraspan 2 IncytePD:3201831 Hs.234863 TSPAN-2 1p12 297 7.48e-05 0 2.699 4.138 5.473 162472 angiogenin, ribonuclease, RNase A

family, 5 IncytePD:2263493 Hs.332764 ANG 14q11.1-

q11.2 298 7.62e-05 0 1.535 0.745 0.765 164487 hypothetical protein FLJ10116 IncytePD:2381415 Hs.79741 FLJ10116 2q35 299 7.81e-05 5e-04 0.732 0.884 1.216 164199 myc-induced nuclear antigen, 53

kDa IncytePD:2200984 Hs.23294 MINA53 3q12.1

300 7.96e-05 0 0.246 0.465 0.622 162662 cytochrome P450, family 4, subfamily F, polypeptide 12

IncytePD:2252321 Hs.180570 CYP4F12 19p13.1

301 8.1e-05 0 0.092 0.376 0.579 161793 dynein, axonemal, heavy IncytePD:4290210 Hs.284259 DNAH9 17p12

polypeptide 9 302 8.13e-05 0 0.117 0.23 0.538 165060 CDP-diacylglycerol synthase

(phosphatidate cytidylyltransferase) 1

IncytePD:1406071 Hs.152981 CDS1 4q21.23

303 8.3e-05 0 0.842 1.186 0.524 162598 lymphocyte adaptor protein IncytePD:1959371 Hs.13131 LNK 12q24 304 8.32e-05 0 0.272 0.519 0.695 166747 insulin receptor IncytePD:1349193 Hs.89695 INSR 19p13.3-

p13.2 305 8.33e-05 0 0.18 0.054 0.058 166687 claudin 1 IncytePD:2257362 Hs.7327 CLDN1 3q28-q29 306 8.37e-05 0 0.8 1.303 2.605 166870 v-erb-b2 erythroblastic leukemia

viral oncogene homolog 3 (avian) IncytePD:1698713 Hs.199067 ERBB3 12q13

307 8.38e-05 0 0.602 0.985 1.592 164412 carboxylesterase 2 (intestine, liver) IncytePD:1804662 Hs.282975 CES2 16q21 308 8.45e-05 0 1.531 0.775 1.137 159879 a disintegrin and metalloproteinase

domain 11 IncytePD:2602282 Hs.6088 ADAM11 17q21.3

310 8.63e-05 0 0.332 1.87 3.669 166770 BRCA1 associated protein IncytePD:1623214 Hs.122764 BRAP 12q24 311 8.7e-05 0 3.821 3.315 1.829 160323 5-aminoimidazole-4-carboxamide

ribonucleotide formyltransferase/IMP cyclohydrolase

IncytePD:2056149 Hs.90280 ATIC 2q35

312 8.75e-05 0 0.138 0.517 0.485 159918 myeloid differentiation primary response gene (88)

IncytePD:1879114 Hs.82116 MYD88 3p22

313 9.09e-05 0 0.847 0.065 0.496 163972 Small proline-rich protein SPRK [human, odontogenic keratocysts, mRNA Partial, 317 nt]

IncytePD:1599293 Hs.46320 1

314 9.21e-05 0 0.756 1.388 1.232 161835 peroxisome biogenesis factor 10 IncytePD:3115936 Hs.247220 PEX10 1p36.32 315 9.35e-05 0 0.91 2.591 4.459 167507 nucleobindin 2 IncytePD:1760517 Hs.3164 NUCB2 11p15.1-

p14 316 9.35e-05 0 2.869 1.298 0.934 160112 phorbol-12-myristate-13-acetate-

induced protein 1 IncytePD:1931117 Hs.96 PMAIP1 18q21.31

317 9.35e-05 0 0.347 1.107 1.911 167661 ectonucleotide pyrophosphatase/phosphodiesterase 3

IncytePD:1807264 Hs.264750 ENPP3 6q22

318 9.39e-05 0 0.518 0.453 1.193 169333 hypothetical protein MGC29643 IncytePD:2016229 Hs.372651 MGC29643 2q21.1 319 9.4e-05 5e-04 0.675 1.937 2.07 160252 paraneoplastic antigen MA1 IncytePD:1399490 Hs.194709 PNMA1 14q24.1 320 9.41e-05 0 3.646 2.69 6.422 168958 Homo sapiens cDNA: FLJ20869

fis, clone ADKA02377. IncytePD:3143579 Hs.194101 12

321 9.45e-05 0 0.837 0.068 0.769 164380 keratin 4 IncytePD:1600453 Hs.3235 KRT4 12q12-q13

322 9.6e-05 0 2.072 0.51 1.746 166117 epiregulin IncytePD:443631 Hs.115263 EREG 4q21.1 323 9.64e-05 5e-04 1.698 0.677 0.733 162098 matrix metalloproteinase 11 IncytePD:1996013 Hs.155324 MMP11 22q11.23

(stromelysin 3) 324 9.67e-05 0 1.763 2.93 4.794 165093 RNA binding protein with multiple

splicing IncytePD:2190284 Hs.80248 RBPMS 8p12-p11

325 9.85e-05 0 1.255 1.174 0.824 167691 tumor necrosis factor receptor superfamily, member 9

IncytePD:191843 Hs.73895 TNFRSF9 1p36

326 9.85e-05 0 1.232 0.412 0.482 164193 piwi-like 2 (Drosophila) IncytePD:2783496 Hs.58248 HIWI2 11q21 327 9.95e-05 0 1.332 1.077 0.889 163611 hypothetical protein FLJ20534 IncytePD:817061 Hs.44344 FLJ20534 4q32.3 328 0.0001004 0 0.322 0.624 0.66 161043 ATP synthase mitochondrial F1

complex assembly factor 2 IncytePD:1648517 Hs.13434 ATPAF2 17

329 0.0001005 0 0.395 1.822 1.361 161626 polycystic kidney disease 1 (autosomal dominant)

IncytePD:1887011 Hs.75813 PKD1 16p13.3

330 0.0001009 0 1.233 1.496 1.065 161446 Splicing factor, arginine/serine-rich, 46kD

IncytePD:2511735 Hs.155160 SRP46 11q22

331 0.0001017 0 0.891 0.279 0.408 166517 gap junction protein, beta 5 (connexin 31.1)

IncytePD:1923289 Hs.198249 GJB5 1p35.1

332 0.0001023 5e-04 0.608 0.866 2.106 168031 transmembrane 4 superfamily member 6

IncytePD:1701627 Hs.121068 TM4SF6 Xq22

333 0.0001043 0 0.518 0.396 0.864 160429 PTK6 protein tyrosine kinase 6 IncytePD:3255437 Hs.51133 PTK6 20q13.3 334 0.0001062 0 1.286 0.695 0.677 159935 troponin T2, cardiac IncytePD:3029650 Hs.296865 TNNT2 1q32 335 0.0001072 0 0.45 0.803 0.709 168332 calcium channel, voltage-

dependent, beta 1 subunit IncytePD:877744 Hs.635 CACNB1 17q21-

q22 336 0.0001076 0 0.681 0.685 1.344 167312 enthoprotin IncytePD:1561222 Hs.132853 ENTH 5q23.1-

q33.3 337 0.000108 0 0.307 0.739 0.95 162374 Mdm2, transformed 3T3 cell

double minute 2, p53 binding protein (mouse)

IncytePD:5505662 Hs.170027 MDM2 12q14.3-q15

338 0.0001088 0 1.674 0.764 0.664 164609 diacylglycerol O-acyltransferase homolog 2 (mouse)

IncytePD:1969044 Hs.334305 DGAT2 11q13.3

339 0.0001114 0 1.502 0.048 0.56 161554 small proline-rich protein 3 IncytePD:2797764 Hs.139322 SPRR3 1q21-q22 340 0.0001125 0 0.714 1.347 1.324 161642 nephronophthisis 4 IncytePD:2655615 Hs.106487 NPHP4 1p36.22 341 0.0001125 0 1.41 3.769 4.24 166841 asparaginase like 1 IncytePD:2009846 Hs.7331 ASRGL1 11q12.2 342 0.0001136 0 1.08 2.057 1.662 164498 KIAA0121 gene product IncytePD:1930294 Hs.155584 KIAA0121 3p25.2 343 0.0001144 0 0.29 0.83 0.735 169716 galactosylceramidase (Krabbe

disease) IncytePD:1430428 Hs.273 GALC 14q31

344 0.0001157 5e-04 1.039 1.911 1.567 161062 chromosome 21 open reading frame 4

345 0.0001163 0 0.754 1.608 2.005 160729 EGF-containing fibulin-like extracellular matrix protein 2

IncytePD:1967983 Hs.6059 EFEMP2 11q13

346 0.0001166 0 0.692 0.868 3.666 167619 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5

IncytePD:3508771 Hs.77062 LILRB5 19q13.4

347 0.0001176 0 0.137 0.425 0.295 164587 Homo sapiens cDNA FLJ10158 fis, clone HEMBA1003463.

IncytePD:3144018 Hs.104627 3

348 0.000118 0 0.558 1.166 1.319 159828 thyroid hormone receptor-associated protein (100 kDa)

IncytePD:1637576 Hs.23106 TRAP100 17q21.1

349 0.000121 5e-04 12.168 19.235 76.274 162202 transferrin IncytePD:843421 Hs.396489 TF 3q21 350 0.0001212 5e-04 0.806 1.281 1.448 166493 zinc finger protein 262 IncytePD:3409136 Hs.150390 ZNF262 1p32-p34 351 0.0001213 0 0.042 0.333 0.563 163375 hypothetical protein

DKFZp547I048 IncytePD:1939384 Hs.200286 DKFZp547I048 1p31.1

352 0.0001218 0 0.303 0.228 0.943 169666 monoamine oxidase A IncytePD:1510714 Hs.183109 MAOA Xp11.4-p11.3

353 0.0001221 0 0.963 0.491 1.259 164239 hypothetical protein MGC16491 IncytePD:3408084 Hs.59771 MGC16491 1p35.3 354 0.0001226 0 0.571 1.438 0.814 165269 solute carrier family 23

(nucleobase transporters), member 1

IncytePD:1259230 Hs.82042 SLC23A1 20p13

355 0.0001235 0 1.592 0.982 1.166 168493 RAB22A, member RAS oncogene family

IncytePD:775737 Hs.288968 RAB22A 20q13.31

356 0.0001248 0 1.296 2.783 4.095 163403 KIAA1324 protein IncytePD:1808121 Hs.104696 KIAA1324 1p13.2 357 0.0001264 0 0.452 1.3 1.357 169699 IK cytokine, down-regulator of

HLA II IncytePD:1921520 Hs.8024 IK 5q31.3

358 0.0001275 0 0.48 0.866 0.696 161312 E1A binding protein p400 IncytePD:2739049 Hs.306094 EP400 12q24.33 359 0.0001288 0 0.972 0.629 0.449 165316 hypothetical protein FLJ13204 IncytePD:2113573 Hs.128905 FLJ13204 9p21.1 360 0.0001288 0 4.767 4.158 2.554 169468 splicing factor, arginine/serine-rich

10 (transformer 2 homolog, Drosophila)

IncytePD:2457759 Hs.30035 SFRS10 3q26.2-q27

361 0.0001294 0 6.732 5.344 3.776 162268 stathmin 1/oncoprotein 18 IncytePD:4059205 Hs.406269 STMN1 1p36.1-p35

362 0.0001301 0 1.132 1.68 2.088 162290 UDP-N-acteylglucosamine pyrophosphorylase 1

IncytePD:1997038 Hs.21293 UAP1 1q23.1

363 0.0001307 5e-04 0.439 0.742 0.764 168245 KIAA0563 gene product IncytePD:1365507 Hs.339808 KIAA0563 17q24.3 364 0.0001313 0 2.141 1.642 1.087 164292 degenerative spermatocyte

homolog, lipid desaturase (Drosophila)

IncytePD:2828192 Hs.185973 DEGS 1q42.12

365 0.0001326 0 0.83 0.69 1.487 161940 occludin IncytePD:3980393 Hs.171952 OCLN 5q13.1 366 0.0001331 0 0.334 0.046 0.267 168788 interleukin 1 receptor antagonist IncytePD:519653 Hs.81134 IL1RN 2q14.2 367 0.0001332 5e-04 0.926 1.448 0.981 168412 M-phase phosphoprotein 9 IncytePD:2508608 Hs.351230 MPHOSPH9 12q24.31 368 0.0001352 0 0.86 1.777 1.149 168433 hypothetical protein FLJ11342 IncytePD:941442 Hs.266514 FLJ11342 3q13.13 369 0.0001374 0 0.81 3.37 3.434 164205 Homo sapiens, clone

IMAGE:5268696, mRNA IncytePD:2396760 Hs.90286 12

370 0.0001402 0 0.777 1.26 1.474 166662 protein kinase C, zeta IncytePD:1888731 Hs.78793 PRKCZ 1p36.33-p36.2

371 0.0001421 0 0.877 1.654 1.463 167618 KIAA0998 protein IncytePD:1444505 Hs.131525 KIAA0998 14q24.3

372 0.0001429 0 0.409 0.181 0.824 162328 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1

IncytePD:2595929 Hs.183583 SERPINB1 6p25

373 0.0001449 5e-04 0.596 1.531 0.922 169726 KIAA1958 protein IncytePD:4109001 Hs.350795 KIAA1958 9q32 374 0.0001463 0 0.611 1.234 2.142 161774 calcium and integrin binding 1

(calmyrin) IncytePD:4626895 Hs.10803 CIB1 15q25.3-

q26 375 0.0001472 0 0.642 1.135 1.628 169185 calpain 3, (p94) IncytePD:2394888 Hs.293267 CAPN3 15q15.1-

q21.1 376 0.0001486 5e-04 0.95 2.348 2.329 165465 KIAA0195 gene product IncytePD:3203789 Hs.301132 KIAA0195 17q25.2 377 0.0001498 0 0.966 3.239 2.637 164737 FERM, RhoGEF (ARHGEF) and

pleckstrin domain protein 1 (chondrocyte-derived)

IncytePD:1966067 Hs.183738 FARP1 13q32.2

378 0.0001501 0 0.559 1.071 1.834 166555 KIAA0633 protein IncytePD:1995122 Hs.33010 COBL 7p12.1 379 0.0001503 5e-04 1.531 0.899 0.844 165307 exostoses (multiple) 1 IncytePD:1375115 Hs.184161 EXT1 8q24.11-

q24.13 380 0.0001519 0 1.539 0.507 0.646 165933 hypothetical protein FLJ21079 IncytePD:1909443 Hs.16512 FLJ21079 6q13 381 0.000154 0 0.423 1.007 0.87 164610 Hermansky-Pudlak syndrome 1 IncytePD:2203196 Hs.83951 HPS1 10q23.1-

q23.3 382 0.0001574 0 0.253 0.476 0.643 165732 calpastatin IncytePD:1342493 Hs.359682 CAST 5q15-q21 383 0.0001574 0 0.736 0.914 3.622 167617 selenoprotein P, plasma, 1 IncytePD:2959255 Hs.275775 SEPP1 5q31 384 0.0001576 0.001 0.242 0.271 0.826 162159 claudin 7 IncytePD:2060261 Hs.278562 CLDN7 17p13 385 0.0001578 0 0.323 0.531 0.317 169148 ESTs, Weakly similar to

IncytePD:2285350 Hs.99216 15

386 0.0001582 0 0.985 1.821 1.661 169057 membrane-bound transcription factor protease, site 1

IncytePD:1816514 Hs.75890 MBTPS1 16q24

387 0.00016 0 0.516 0.983 1.357 164978 caspase 10, apoptosis-related cysteine protease

IncytePD:3984879 Hs.5353 CASP10 2q33-q34

388 0.0001604 5e-04 0.522 0.3 2.119 168662 annexin A1 IncytePD:79576 Hs.78225 ANXA1 9q12-q21.2

389 0.0001605 5e-04 1.444 1.152 0.787 165265 E2F transcription factor 3 IncytePD:1731732 Hs.1189 E2F3 6p22 390 0.0001615 0 0.253 0.321 0.591 163228 hypothetical protein LOC144100 IncytePD:1663925 Hs.12332 LOC144100 11p15.1 391 0.0001617 0 2.702 2.904 1.734 167736 polymerase (DNA directed), alpha IncytePD:1719446 Hs.267289 POLA Xp22.1-

p21.3 392 0.0001621 5e-04 0.597 0.945 1.335 161081 meningioma expressed antigen 6

(coiled-coil proline-rich) IncytePD:2378482 Hs.117242 MGEA6 14q

393 0.0001649 0 0.72 0.953 0.767 164022 chromosome 14 open reading frame 117

394 0.0001674 0 2.096 3.183 2.733 162546 multiple endocrine neoplasia I IncytePD:1845962 Hs.423348 MEN1 11q13 395 0.0001693 0 0.99 0.596 0.673 164016 hypothetical protein FLJ33817 IncytePD:1638450 Hs.22176 FLJ33817 17p13.3 396 0.0001724 0 0.4 0.673 0.648 160022 cyclin-dependent kinase 3 IncytePD:1698903 Hs.100009 CDK3 17q22-

qter 397 0.0001732 0 0.202 0.898 1.069 163834 centrin, EF-hand protein, 2 IncytePD:1450639 Hs.82794 CETN2 Xq28 398 0.0001747 0 1.963 0.575 0.799 165255 Homo sapiens, clone

399 0.0001761 0 0.926 0.466 0.491 164299 membrane-spanning 4-domains, subfamily A, member 6A

IncytePD:2349263 Hs.17914 MS4A6A 11q12.1

400 0.0001771 0 0.616 0.413 0.3 164155 ERO1-like beta (S. cerevisiae) IncytePD:2073339 Hs.150763 ERO1LB 1q42.2-q43

401 0.0001787 0 1.46 0.563 0.787 162983 ADP-ribosylation-like factor 8 IncytePD:3367716 Hs.220929 ARL8 10p12.33 402 0.0001828 5e-04 0.71 2.101 4.892 160825 profilin 2 IncytePD:1979601 Hs.91747 PFN2 3q25.1-

q25.2 403 0.0001833 0 0.116 0.372 0.247 160065 nuclear receptor subfamily 3, group

C, member 2 IncytePD:1678071 Hs.1790 NR3C2 4q31.1

404 0.0001876 0 0.927 1.415 4.972 165656 argininosuccinate synthetase IncytePD:1981145 Hs.160786 ASS 9q34.1 405 0.0001891 0 0.82 1.824 1.497 169163 TATA box binding protein (TBP)-

associated factor, RNA polymerase I, C, 110kDa

IncytePD:1868217 Hs.153022 TAF1C 16q24

406 0.000193 5e-04 0.678 1.286 1.554 161790 KIAA0469 gene product IncytePD:2674277 Hs.7764 KIAA0469 1p36.23 407 0.0001936 5e-04 4.948 1.551 3.475 167088 extracellular matrix protein 1 IncytePD:1965806 Hs.81071 ECM1 1q21 408 0.000194 0 0.333 0.828 0.644 164154 Homo sapiens cDNA FLJ11606

fis, clone HEMBA1003942. IncytePD:1730917 Hs.283643 1

409 0.000196 0.001 0.874 0.817 0.617 160481 KIAA0663 gene product IncytePD:2057266 Hs.17969 KIAA0663 1q32.1 410 0.0001968 0 2.2 4.062 4.024 160478 HLA-B associated transcript 3 IncytePD:1942845 Hs.274348 BAT3 6p21.3 411 0.0002025 5e-04 0.493 0.85 0.743 162170 iduronate 2-sulfatase (Hunter

syndrome) IncytePD:2776385 Hs.172458 IDS Xq28

412 0.0002034 5e-04 1.047 2.191 1.811 164492 tetracycline transporter-like protein IncytePD:1856947 Hs.157145 TETRAN 4p16.3 413 0.0002044 5e-04 0.87 0.254 1.157 164116 zinc finger protein 185 (LIM

domain) IncytePD:2510927 Hs.16622 ZNF185 Xq28

414 0.0002059 0 0.597 1.18 1.013 160716 KIAA0819 protein IncytePD:1910948 Hs.301866 KIAA0819 22q11.1 415 0.0002102 0 0.465 1.31 0.997 160817 nuclear RNA export factor 1 IncytePD:1890753 Hs.323502 NXF1 11q12-

q13 416 0.0002102 0 4.259 2.518 1.575 161264 hypothetical protein MGC24665 IncytePD:2211367 Hs.347524 MGC24665 16p13.2 417 0.0002108 0 0.932 2.003 2.684 167471 ATP-binding cassette, sub-family

C (CFTR/MRP), member 6 IncytePD:2877376 Hs.274260 ABCC6 16p13.1

418 0.000211 0 1.013 0.543 0.571 168220 syntaxin 6 IncytePD:2549507 Hs.157144 STX6 1q24.3 419 0.0002113 0 0.07 0.232 0.463 169181 zinc finger protein 76 (expressed in

testis) IncytePD:1870362 Hs.29222 ZNF76 6p21.3-

p21.2 420 0.0002114 0 0.163 0.571 0.467 163856 ESTs IncytePD:3144431 Hs.56220 1 421 0.0002118 0 0.485 0.95 0.853 163016 hypothetical protein BC013576 IncytePD:1977115 Hs.348493 LOC114928 Xq22.1 422 0.0002118 0 0.291 0.381 1.106 165464 nebulette IncytePD:1980445 Hs.5025 NEBL 10p12 423 0.0002128 0 0.305 0.457 0.807 161665 ESTs IncytePD:2820372 Hs.366054 17

424 0.0002141 0 0.488 0.831 0.917 160796 hypothetical protein 628 IncytePD:1559636 Hs.181349 LOC56270 17q25.3 425 0.0002144 0 0.33 0.705 1.125 162401 short-chain

dehydrogenase/reductase 1 IncytePD:2132634 Hs.17144 SDR1 1p36.1

426 0.0002192 0.001 0.495 1.006 1.303 165066 target of myb1 (chicken) IncytePD:3119252 Hs.9482 TOM1 22q13.1 427 0.0002198 5e-04 0.169 0.464 0.507 167726 chromosome 9 open reading frame

19 IncytePD:1467308 Hs.302766 C9orf19 9p13-p12

428 0.0002201 0 2.192 1.282 1.358 164093 Homo sapiens, clone IMAGE:4498705, mRNA

IncytePD:2956730 Hs.180908 10

429 0.0002205 5e-04 1.256 0.912 0.785 162908 RAB21, member RAS oncogene family

IncytePD:2597109 Hs.184627 RAB21 12q15

430 0.0002213 0 0.72 1.715 1.345 167016 interleukin enhancer binding factor 3, 90kDa

IncytePD:1674263 Hs.256583 ILF3 19p13.2

431 0.0002223 0.0025 1.567 0.99 6.192 166858 retinoic acid induced 3 IncytePD:2060304 Hs.194691 RAI3 12p13-p12.3

432 0.0002224 5e-04 0.566 0.814 0.796 168873 ESTs IncytePD:2749278 Hs.112050 10 433 0.000227 5e-04 0.375 0.66 0.72 163071 Homo sapiens cDNA: FLJ21409

fis, clone COL03924. IncytePD:1340424 Hs.172129 5

434 0.0002333 0 0.863 1.553 1.071 168121 Homo sapiens clone FBD3 Cri-du-chat critical region mRNA

IncytePD:1910705 Hs.432862 2

435 0.0002335 0 6.583 3.727 2.39 162403 topoisomerase (DNA) II alpha 170kDa

IncytePD:129009 Hs.156346 TOP2A 17q21-q22

436 0.00024 0 0.597 0.974 0.823 166983 hypothetical protein FLJ21877 IncytePD:584794 Hs.16063 FLJ21877 2p21 437 0.0002403 0 0.33 0.715 0.612 159857 RNA binding motif protein 5 IncytePD:3596638 Hs.201675 RBM5 3p21.3 438 0.0002417 0 0.539 1.313 1.011 161016 nuclear RNA export factor 1 IncytePD:1722870 Hs.323502 NXF1 11q12-

q13 439 0.0002423 0 0.303 0.565 0.617 165484 ESTs IncytePD:2820853 Hs.443584 14 440 0.0002428 5e-04 0.485 0.682 1.544 162351 CD59 antigen p18-20 (antigen

identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)

IncytePD:2060621 Hs.278573 CD59 11p13

441 0.0002443 5e-04 1.076 0.599 0.672 168712 Human clone 23612 mRNA sequence

IncytePD:308761 Hs.82141 21

442 0.0002447 5e-04 0.543 0.772 0.514 164415 sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)

IncytePD:471870 Hs.31176 SIRT1 10q22.1

443 0.0002503 5e-04 0.999 0.557 0.866 168241 KIAA1295 protein IncytePD:1208611 Hs.26204 KIAA1295 5q35.2 444 0.0002504 0 0.27 0.255 0.644 160881 transmembrane protease, serine 2 IncytePD:991163 Hs.318545 TMPRSS2 21q22.3 445 0.000251 5e-04 0.883 2.272 1.62 168745 zinc finger protein 3 (A8-51) IncytePD:997067 Hs.155470 ZNF3 7q22.1 446 0.0002554 0 0.236 0.442 0.388 168393 eukaryotic translation initiation

factor 3, subunit 1 alpha, 35kDa IncytePD:1998519 Hs.173987 EIF3S1 15q15.1

447 0.0002576 0 1.347 2.285 2.085 161358 nuclear pore complex interacting IncytePD:2715266 Hs.251928 NPIP 16p13-

protein p11 448 0.0002587 0 0.64 1.24 1.822 164149 putative ankyrin-repeat containing

protein IncytePD:2626237 Hs.4996 DKFZP564D166 17q23.3

449 0.0002596 0 1.096 0.541 0.601 168299 Homo sapiens cDNA FLJ37042 fis, clone BRACE2011947.

IncytePD:1208908 Hs.432542 5

450 0.0002601 0 0.084 0.351 0.57 161308 glutathione S-transferase A3 IncytePD:2658641 Hs.102484 GSTA3 6p12.1 451 0.0002616 0 0.963 1.937 1.961 161106 cyclin-dependent kinase (CDC2-

like) 10 IncytePD:1695859 Hs.77313 CDK10 16q24

452 0.000262 5e-04 1.665 0.632 0.747 168080 ESTs, Moderately similar to neuronal thread protein [Homo sapiens] [H.sapiens]

IncytePD:1293515 Hs.97109 1

453 0.0002634 5e-04 1.274 0.686 0.895 160455 LIS1-interacting protein NUDEL; endooligopeptidase A

IncytePD:2132359 Hs.3850 NUDEL 17p13.1

454 0.0002638 0 1.499 0.571 0.762 165226 proteasome (prosome, macropain) subunit, beta type, 2

IncytePD:1986028 Hs.432607 PSMB2 1p34.2

455 0.0002649 0 1.085 0.848 0.774 164832 hypothetical protein FLJ11294 IncytePD:2871116 Hs.107000 FLJ11294 2q14.3 456 0.000267 0 1.5 4.555 2.665 164622 CD99 antigen IncytePD:3031028 Hs.433387 CD99 Xp22.32 457 0.0002673 0 0.665 1.428 1.589 165886 RAB, member of RAS oncogene

family-like 4 IncytePD:583177 Hs.50267 RABL4 22q13.1

458 0.0002676 0 1.379 2.156 2.709 161607 argininosuccinate lyase IncytePD:3283759 Hs.61258 ASL 7cen-q11.2

459 0.0002776 5e-04 0.187 0.4 0.78 165782 actin binding LIM protein 1 IncytePD:1722853 Hs.158203 ABLIM1 10q25 460 0.0002779 0 1.83 0.674 1.329 161558 keratin, hair, basic, 3 IncytePD:1719403 Hs.182506 KRTHB3 12q13 461 0.0002781 0 1.116 0.41 0.877 160276 transglutaminase 1 (K polypeptide

epidermal type I, protein-glutamine-gamma-glutamyltransferase)

IncytePD:459817 Hs.22 TGM1 14q11.2

462 0.0002781 0 0.426 0.634 0.674 167523 cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene

IncytePD:2796468 Hs.330780 CYP2B7 19q13.2

463 0.0002786 0.001 0.59 1.684 1.66 162313 transforming growth factor beta-stimulated protein TSC-22

IncytePD:197908 Hs.114360 TSC22 13q14

464 0.000285 0.001 1.615 1.333 2.894 161244 ADP-ribosylation factor 4-like IncytePD:2852403 Hs.183153 ARF4L 17q12-q21

465 0.0002852 0 0.222 0.375 0.682 163385 Homo sapiens mRNA; cDNA DKFZp564J0323 (from clone DKFZp564J0323)

IncytePD:2294339 Hs.99766 11

466 0.0002856 5e-04 1.739 0.425 0.974 165579 visinin-like 1 IncytePD:1741701 Hs.2288 VSNL1 2p24.3 467 0.000291 5e-04 0.895 1.404 1.292 165108 Incyte EST IncytePD:2685601 468 0.000291 0 0.086 0.127 0.429 167405 flavin containing monooxygenase 2 IncytePD:3492330 Hs.132821 FMO2 1q23-q25 469 0.000302 0 0.432 0.643 1.239 167196 3-hydroxybutyrate dehydrogenase IncytePD:1922001 Hs.76893 BDH 3q29

(heart, mitochondrial) 470 0.0003048 0 0.924 0.07 0.745 168898 small proline-rich protein 2A IncytePD:24263 Hs.355542 SPRR2A 1q21-q22 471 0.0003049 0 6.083 3.134 3.992 169400 fibronectin 1 IncytePD:3553729 Hs.287820 FN1 2q34 472 0.0003059 0 0.208 0.688 0.522 160138 nischarin IncytePD:1809315 Hs.26285 NISCH 3p21.1 473 0.0003063 0 1.739 0.5 0.691 161384 cofactor required for Sp1

transcriptional activation, subunit 2, 150kDa

IncytePD:3969924 Hs.407604 CRSP2 Xp11.4-p11.2

474 0.0003074 0.002 0.657 0.742 1.382 161577 Homo sapiens DNA from chromosome 19, cosmid F21856

IncytePD:3615515

475 0.000309 5e-04 1.377 0.826 0.464 168250 steroidogenic acute regulatory protein

IncytePD:218387 Hs.3132 STAR 8p11.2

476 0.0003177 0 1.367 2.103 1.976 167182 splicing factor, arginine/serine-rich 4

IncytePD:1967517 Hs.76122 SFRS4 1p35.2

477 0.0003209 0 0.348 0.537 0.885 166697 period homolog 3 (Drosophila) IncytePD:2289901 Hs.12592 PER3 1p36.22 478 0.000321 0 0.986 0.416 0.411 161689 growth hormone receptor IncytePD:2639411 Hs.125180 GHR 5p13-p12 479 0.0003221 0 1.261 0.962 0.845 165197 ESTs IncytePD:3052608 Hs.269386 2 480 0.0003222 0.0015 0.385 0.327 1.079 159905 sushi-repeat protein IncytePD:3598293 Hs.126782 SRPUL Xq21.33-

q23 481 0.0003311 5e-04 1.304 0.97 2.258 160396 hypothetical protein from clone

643 IncytePD:1451876 Hs.206501 LOC57228 12q13.12

482 0.0003312 5e-04 1.063 0.828 0.666 168481 Homo sapiens cDNA FLJ32368 fis, clone PUAEN1000275.

IncytePD:1997493 Hs.350268 1

483 0.0003381 0.001 0.806 1.427 1.806 161134 melanoma antigen, family D, 2 IncytePD:2418918 Hs.4943 MAGED2 Xp11.4-p11.1

484 0.0003398 0 3.023 2.193 1.475 161544 CHK1 checkpoint homolog (S. pombe)

IncytePD:2594058 Hs.20295 CHEK1 11q24-q24

485 0.000343 0 0.238 0.509 0.605 160559 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

IncytePD:1634540 Hs.102307 SLC13A2 17p11.1-q11.1

486 0.0003434 0 0.197 0.323 0.537 167671 arachidonate 15-lipoxygenase IncytePD:2798041 Hs.73809 ALOX15 17p13.3 487 0.0003446 0 0.53 0.922 0.826 160408 PHD finger protein 2 IncytePD:2790394 Hs.93868 PHF2 9q22.31 488 0.0003501 0 0.267 0.412 0.724 168186 midline 1 (Opitz/BBB syndrome) IncytePD:2170171 Hs.27695 MID1 Xp22 489 0.0003518 0 1.424 0.425 0.742 164017 KIAA0450 gene product IncytePD:2799177 Hs.170156 KIAA0450 1p36.32 490 0.0003547 0 0.562 0.187 0.862 168157 ESTs IncytePD:931235 Hs.445586 19 491 0.0003623 0 0.391 0.791 1.004 167377 aldehyde dehydrogenase 3 family,

member A2 IncytePD:2009053 Hs.159608 ALDH3A2 17p11.2

492 0.0003655 5e-04 0.329 0.25 0.81 161565 prostate stem cell antigen IncytePD:1900949 Hs.423634 PSCA 8q24.2 493 0.0003673 5e-04 0.508 0.67 0.919 164401 ALFY IncytePD:1218823 Hs.198135 ALFY 4q21.3 494 0.0003736 5e-04 0.265 0.528 0.462 166142 deiodinase, iodothyronine, type II IncytePD:2869983 Hs.154424 DIO2 14q24.2-

q24.3 495 0.0003765 0 0.567 1.193 1.067 165628 spastic paraplegia 7, paraplegin IncytePD:1454012 Hs.296847 SPG7 16q24.3

(pure and complicated autosomal recessive)

496 0.000379 0 1.675 1.421 1.14 163139 general transcription factor IIIC, polypeptide 4, 90kDa

IncytePD:3462016 Hs.22302 GTF3C4 9q34.3

497 0.0003836 0 1.402 2.083 2.718 168974 hypothetical protein BC007772 IncytePD:210233 Hs.105640 LOC93109 3q29 498 0.000396 0 2.064 2.424 1.502 163199 Bardet-Biedl syndrome 2 IncytePD:1723772 Hs.332633 BBS2 16q21 499 0.0003982 0 0.769 1.383 1.212 164130 KIAA0194 protein IncytePD:1429306 Hs.216958 KIAA0194 5q33.1 500 0.0003995 5e-04 0.398 0.642 0.804 168624 Homo sapiens mRNA; cDNA

DKFZp686D0521 (from clone DKFZp686D0521)

IncytePD:2132466 Hs.356786 9

501 0.0004063 5e-04 1.739 3.274 3.787 165416 single stranded DNA binding protein 4

IncytePD:1760716 Hs.324618 SSBP4 19p13.1

502 0.000411 5e-04 0.772 0.842 0.542 163753 Homo sapiens clone HQ0290 IncytePD:639847 Hs.446574 1 503 0.0004191 0 0.22 0.62 0.694 163752 CGI-43 protein IncytePD:2040650 504 0.0004256 5e-04 0.446 0.772 0.732 165048 coronin, actin binding protein, 2A IncytePD:2210264 Hs.44396 CORO2A 9q22.3 505 0.0004496 0 1.095 0.706 0.807 160767 death effector domain containing IncytePD:1877071 Hs.169681 DEDD 1q23.1 506 0.0004539 0 0.487 0.569 1.168 168204 cytochrome P450, family 24,

subfamily A, polypeptide 1 IncytePD:3118873 Hs.89663 CYP24A1 20q13

507 0.0004571 0 0.48 0.297 0.852 165942 transforming growth factor, alpha IncytePD:3125996 Hs.170009 TGFA 2p13 508 0.0004572 0 0.557 0.48 0.982 168530 EphB3 IncytePD:1227385 Hs.2913 EPHB3 3q21-qter 509 0.0004607 5e-04 1.601 1.147 0.591 165414 hypothetical protein FLJ20641 IncytePD:415720 Hs.121553 FLJ20641 12q23.1 510 0.0004639 0.001 0.909 0.504 0.308 160653 Spi-B transcription factor (Spi-

1/PU.1 related) IncytePD:1561204 Hs.192861 SPIB 19q13.3-

q13.4 511 0.0004678 0 4.689 3.158 2.223 160413 uridine monophosphate kinase IncytePD:1959569 Hs.95734 UMPK 1q23 512 0.0004737 0.002 2.181 5.397 8.269 166359 tubulin, beta polypeptide IncytePD:3334367 Hs.336780 TUBB 6p21.3 513 0.0004744 0 0.224 0.558 0.481 163259 ESTs IncytePD:2556393 Hs.381113 4 514 0.0004818 5e-04 0.156 0.441 0.306 164647 Homo sapiens cDNA FLJ10158

fis, clone HEMBA1003463. IncytePD:1967531 Hs.104627 3

515 0.0004818 0.001 0.17 0.262 0.85 162158 activated leukocyte cell adhesion molecule

IncytePD:1793853 Hs.10247 ALCAM 3q13.1

516 0.0004852 0 0.281 0.647 0.661 166673 connector enhancer of KSR-like (Drosophila kinase suppressor of ras)

IncytePD:4001076 Hs.16232 CNK1 1p35.3

517 0.0004867 0.001 0.661 1.537 0.945 169678 Homo sapiens, clone IMAGE:5262734, mRNA

IncytePD:2957644 Hs.296031 X

518 0.0004897 5e-04 0.586 1.34 1.343 163539 cathepsin F IncytePD:1569235 Hs.11590 CTSF 11q13 519 0.0004899 0 0.451 0.983 0.85 165387 cyclin L2 IncytePD:2886955 Hs.143601 CCNL2 1p36.33 520 0.0004946 0 1.222 2.358 5.423 166426 protein S (alpha) IncytePD:2592991 Hs.64016 PROS1 3p11-

q11.2 521 0.0004961 0.0015 0.547 1.117 0.793 169631 Homo sapiens cDNA: FLJ23005

fis, clone LNG00396, highly IncytePD:447148 Hs.58220 17

similar to AF055023 Homo sapiens clone 24723 mRNA sequence.

522 0.0004964 0 1.057 0.547 0.569 164113 NICE-5 protein IncytePD:2396483 Hs.337078 HSA243666 1q21.3 523 0.0004983 5e-04 1.227 0.751 0.893 164952 very low density lipoprotein

receptor IncytePD:1690952 Hs.73729 VLDLR 9p24

524 0.0004986 5e-04 0.653 0.959 0.566 164506 mannosidase, beta A, lysosomal IncytePD:1805840 Hs.115945 MANBA 4q22-q25 525 0.0004996 5e-04 17.149 5.945 6.566 161765 caveolin 1, caveolae protein,

22kDa IncytePD:4271973 Hs.74034 CAV1 7q31.1

526 0.0005022 0 1.501 0.713 0.886 160530 KIAA1357 protein IncytePD:1266388 Hs.170162 KIAA1357 6q23.3 527 0.0005061 0 0.311 0.892 1.302 167524 ESTs, Weakly similar to

IncytePD:2369929 Hs.99841 2

528 0.0005091 0 3.017 2.708 1.971 165622 integrin, beta 4 IncytePD:1930711 Hs.85266 ITGB4 17q11-qter

529 0.0005112 0 3.92 3.869 2.321 167571 sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila

IncytePD:2612729 Hs.128759 SARM 17

530 0.0005201 5e-04 0.61 0.741 1.083 161730 enhancer of zeste homolog 1 (Drosophila)

IncytePD:2964704 Hs.194669 EZH1 17q21.1-q21.3

531 0.0005222 5e-04 1.03 0.677 0.592 164045 ESTs IncytePD:2346766 Hs.446670 2 532 0.0005241 0 3.104 9.295 5.644 160068 enolase 2, (gamma, neuronal) IncytePD:1672630 Hs.146580 ENO2 12p13 533 0.0005259 0 0.975 1.595 1.373 166990 stromal cell protein IncytePD:334820 Hs.292154 LOC55974 1q21.3 534 0.0005271 0 1.234 0.608 0.885 164441 Incyte EST IncytePD:1618195 535 0.0005299 0 0.631 0.691 1.017 166145 DKFZP434C212 protein IncytePD:1282176 Hs.172069 DKFZP434C212 9q34.11 536 0.0005321 5e-04 0.486 1.97 1.43 168594 ADP-ribosylation factor-like 3 IncytePD:67300 Hs.182215 ARL3 10q23.3 537 0.0005329 0.0015 0.427 0.599 1.001 160197 villin 2 (ezrin) IncytePD:615749 Hs.155191 VIL2 6q25.2-

q26 538 0.0005345 5e-04 0.531 0.751 0.498 160132 zinc finger protein with interaction

domain IncytePD:3728922 Hs.3053 ZID 9q34.11

539 0.000538 0.001 1.593 0.86 1.092 169469 major histocompatibility complex, class II, DM beta

IncytePD:735149 Hs.1162 HLA-DMB 6p21.3

540 0.0005386 0 0.806 1.505 1.147 166768 ESTs IncytePD:496874 Hs.125494 X 541 0.000539 0.001 0.387 0.806 0.82 165506 tumor protein p53 binding protein,

1 IncytePD:618622 Hs.170263 TP53BP1 15q15-

q21 542 0.0005413 0 1.223 0.532 0.784 168948 nuclear receptor subfamily 4, group

A, member 3 IncytePD:1919520 Hs.80561 NR4A3 9q22

543 0.0005416 0 0.958 0.567 0.894 160991 interleukin 13 receptor, alpha 1 IncytePD:1476267 Hs.285115 IL13RA1 Xq24 544 0.0005468 0 0.48 0.813 0.791 167221 Human clone CE29 7.2

(CAC)n/(GTG)n repeat-containing mRNA.

IncytePD:3704132 Hs.133065 2

545 0.0005479 0.0015 0.445 0.622 1.018 167427 potassium voltage-gated channel, IncytePD:2296270 Hs.47584 KCNS3 2p24

delayed-rectifier, subfamily S, member 3

546 0.0005524 0 1.53 0.479 0.636 165205 paired mesoderm homeo box 1 IncytePD:3118038 Hs.443452 PMX1 1q24 547 0.0005527 0 1.233 0.746 0.483 166760 degenerative spermatocyte

homolog, lipid desaturase (Drosophila)

IncytePD:2060369 Hs.185973 DEGS 1q42.12

548 0.0005532 0.001 0.34 0.866 0.772 169734 ESTs IncytePD:2917169 Hs.42294 19 549 0.0005617 0 3.862 3.716 2.287 169095 centromere protein A, 17kDa IncytePD:2444942 Hs.1594 CENPA 2p24-p21 550 0.0005638 0 1.25 0.871 0.921 162751 ESTs, Weakly similar to

NAL2_HUMAN NACHT-, LRR- and PYD-containing protein 2 (Nucleotide-binding site protein 1) [H.sapiens]

IncytePD:2751667 Hs.285363 19

551 0.0005649 0 1.081 0.617 0.475 163517 zinc finger protein 281 IncytePD:2260783 Hs.59757 ZNF281 1q32.1 552 0.0005661 0 0.457 0.445 1.219 165363 bone morphogenetic protein 1 IncytePD:1804401 Hs.1274 BMP1 8p21 553 0.0005708 0 2.288 0.593 1.769 166165 integrin, beta 3 (platelet

glycoprotein IIIa, antigen CD61) IncytePD:682741 Hs.87149 ITGB3 17q21.32

554 0.0005749 0 0.129 0.41 0.331 161039 kinase insert domain receptor (a type III receptor tyrosine kinase)

IncytePD:1480063 Hs.12337 KDR 4q11-q12

555 0.0005773 5e-04 1.534 0.645 0.803 166258 ocular albinism 1 (Nettleship-Falls) IncytePD:2808289 Hs.74124 OA1 Xp22.3 556 0.000578 0.001 0.604 1.151 1.202 163757 centaurin, gamma 3 IncytePD:884855 Hs.286084 CENTG3 7q36.1 557 0.0005813 5e-04 0.111 0.157 0.863 161601 ATPase, Class V, type 10B IncytePD:2532486 Hs.109358 ATP10B 5q34 558 0.0005826 0 0.158 0.406 0.453 162413 interferon-stimulated transcription

factor 3, gamma 48kDa IncytePD:1942550 Hs.1706 ISGF3G 14q11.2

559 0.0005836 0.0015 1.362 0.758 1.128 161709 hypothetical protein FLJ11560 IncytePD:1990361 Hs.301696 FLJ11560 9p13.1 560 0.0005848 0.0015 1.395 0.918 0.801 169022 chromosome 1 open reading frame

561 0.0005872 0.001 1.615 3.249 3.693 163347 dimethylarginine dimethylaminohydrolase 2

IncytePD:1911142 Hs.247362 DDAH2 6p21.3

562 0.0005887 0 0.263 0.376 0.547 164327 ESTs, Weakly similar to hypothetical protein FLJ20378 [Homo sapiens] [H.sapiens]

IncytePD:2833929 Hs.97579 17

563 0.0005905 5e-04 0.804 1.008 1.027 168363 WD40 and FYVE domain containing 2

IncytePD:2092446 Hs.16400 WDFY2 13q14.12

564 0.000598 0 0.48 1.407 0.947 169247 NIMA (never in mitosis gene a)- related kinase 9

IncytePD:1661837 Hs.7200 NEK9 14q24.2

565 0.0005986 0 1.176 0.674 0.786 166385 cyclin-dependent kinase 5, regulatory subunit 1 (p35)

IncytePD:1741702 Hs.93597 CDK5R1 17q11.2

566 0.000608 5e-04 0.694 0.99 0.831 160781 RNA helicase-related protein IncytePD:2132758 Hs.8765 RNAHP 17q24.1 567 0.0006091 0 1.086 0.772 1.323 166046 5'-nucleotidase, cytosolic II IncytePD:2474690 Hs.138593 NT5C2 10q24.32 568 0.0006094 0.002 0.027 0.045 0.234 169113 gamma-aminobutyric acid (GABA) IncytePD:1824443 Hs.70725 GABRP 5q33-q34

A receptor, pi 569 0.0006106 0.001 0.796 0.282 1.06 169654 BENE protein IncytePD:1560987 Hs.185055 BENE 2q13 570 0.0006119 0 9.183 3.967 2.447 164132 MAD2 mitotic arrest deficient-like

1 (yeast) IncytePD:2414624 Hs.79078 MAD2L1 4q27

571 0.0006125 0.001 3.514 4.807 6.216 164814 glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)

IncytePD:1867652 Hs.1691 GBE1 3p12.3

572 0.000613 0.001 0.996 0.765 1.561 162107 histamine receptor H1 IncytePD:1210839 Hs.1570 HRH1 3p25 573 0.0006136 0 0.075 0.241 0.259 166700 potassium inwardly-rectifying

channel, subfamily J, member 2 IncytePD:630604 Hs.1547 KCNJ2 17q23.1-

q24.2 574 0.0006142 0.001 4.24 3.105 1.891 162041 H2A histone family, member Z IncytePD:1466276 Hs.119192 H2AFZ 4q24 575 0.0006185 0 1.775 0.732 1.002 167838 Homo sapiens, clone MGC:43036

IMAGE:4839025, mRNA, complete cds

IncytePD:2937340 Hs.97717 7

576 0.0006237 0.001 0.827 1.176 0.939 169112 hypothetical protein FLJ10900 IncytePD:587420 Hs.16277 FLJ10900 7q11.21 577 0.0006243 0.001 0.768 0.428 0.962 162745 solute carrier family 1

(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

578 0.0006249 0 0.573 1.09 1.196 162737 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)

IncytePD:3148152 Hs.113271 ABO 9q34.1-q34.2

579 0.0006278 5e-04 1.797 0.313 0.966 161767 sciellin IncytePD:4554357 Hs.115166 SCEL 13q22 580 0.0006346 0.001 0.233 0.184 0.546 165202 ESTs, Weakly similar to neuronal

thread protein [Homo sapiens] [H.sapiens]

IncytePD:1933018 Hs.125376 2

581 0.0006454 5e-04 1.653 0.898 3.575 160500 kallikrein 11 IncytePD:2668780 Hs.57771 KLK11 19q13.3-q13.4

582 0.0006472 5e-04 1.112 1.918 1.443 164513 hypothetical protein FLJ20551 IncytePD:1924027 Hs.7994 FLJ20551 3p21.33 583 0.0006514 0 0.136 0.106 0.309 169495 heparan sulfate (glucosamine) 3-O-

sulfotransferase 1 IncytePD:513943 Hs.40968 HS3ST1 4p16

584 0.000652 5e-04 0.621 1.11 1.525 169013 quiescin Q6 IncytePD:1854220 Hs.77266 QSCN6 1q24 585 0.0006527 0 0.46 0.859 0.804 166351 chromosome 21 open reading

frame 2 IncytePD:2844768 Hs.388842 C21orf2 21q22.3

586 0.0006581 0 0.629 0.766 0.494 168357 zinc finger protein 265 IncytePD:1845253 Hs.194718 ZNF265 1p31 587 0.0006609 0 1.038 0.629 0.665 164477 hypothetical protein FLJ32115 IncytePD:2374046 Hs.293902 FLJ32115 12p13.1 588 0.0006662 0.0015 0.51 1.006 0.98 163755 ESTs, Weakly similar to Solute

carrier family 11 member 1 IncytePD:75549 Hs.22049 19

(natural resistance-associated macrophage protein 1); Natural resistance-associated macrophage protein; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 [Rattus

589 0.0006734 5e-04 0.72 1.254 1.13 167379 spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2)

IncytePD:664095 Hs.76253 SCA2 12q24

590 0.0006795 5e-04 0.941 0.855 0.649 160456 KIAA0903 protein IncytePD:2968321 Hs.16218 KIAA0903 2p14 591 0.0006867 0.001 0.232 0.578 0.744 162347 dynein, axonemal, light

polypeptide 4 IncytePD:1242664 Hs.182595 DNAL4 22q13.1

592 0.0006867 0.001 0.515 1.406 1.091 166639 SET binding protein 1 IncytePD:2903158 Hs.151717 SETBP1 18q21.1 593 0.0006898 0 0.708 0.472 2.032 164722 thyroid hormone receptor interactor

4 IncytePD:1970421 Hs.116784 TRIP4 15q22.1

594 0.0006904 5e-04 1.621 0.589 0.924 164659 soluble liver antigen/liver pancreas antigen

IncytePD:3231844 Hs.161436 SLA/LP 4p15.31

595 0.0006931 0.0015 0.597 0.756 0.388 168918 lamin B receptor IncytePD:564104 Hs.152931 LBR 1q42.1 596 0.0006968 0.0025 1.072 0.585 0.852 162691 heat shock 70kDa protein 1-like IncytePD:535732 Hs.80288 HSPA1L 6p21.3 597 0.0006972 0 0.5 0.94 0.744 166945 phosphorylase kinase, alpha 2

(liver) IncytePD:2365335 Hs.54941 PHKA2 Xp22.2-

p22.1 598 0.0006983 5e-04 8.777 5.855 4.2 168912 likely ortholog of mouse gene rich

cluster, C8 gene IncytePD:44938 Hs.30114 GRCC8 12p13

599 0.0007015 5e-04 0.506 0.85 0.719 168038 ariadne homolog 2 (Drosophila) IncytePD:1698803 Hs.241558 ARIH2 3p21.2-p21.3

600 0.0007083 0.001 1.62 1.048 1.638 161201 serine/threonine kinase 24 (STE20 homolog, yeast)

IncytePD:1755014 Hs.168913 STK24 13q31.2-q32.3

601 0.0007085 0.001 0.387 0.87 0.81 161789 CDC14 (cell division cycle 14, S. cerevisiae) homolog B

IncytePD:3438934

602 0.0007171 0 1.472 0.73 0.71 161496 chloride intracellular channel 2 IncytePD:2581144 Hs.54570 CLIC2 Xq28 603 0.0007208 0 0.23 0.176 0.647 165543 UDP-N-acetyl-alpha-D-

IncytePD:1758055 Hs.278611 GALNT3 2q24-q31

604 0.0007284 0 0.523 0.827 0.779 162248 Incyte EST IncytePD:2131862 605 0.0007299 0.0015 0.414 0.977 0.573 160681 biglycan IncytePD:1963963 Hs.821 BGN Xq28 606 0.000735 0 1.239 1.714 1.984 166776 autocrine motility factor receptor IncytePD:1630117 Hs.80731 AMFR 16q21 607 0.0007352 0 0.478 0.681 0.677 166153 pancreatic lipase-related protein 1 IncytePD:2084515 Hs.73923 PNLIPRP1 10q26.11 608 0.0007356 0 0.395 0.617 0.601 161233 Incyte EST IncytePD:1602194 609 0.000736 5e-04 1.166 0.497 0.62 163132 ESTs IncytePD:2676494 Hs.433013 8 610 0.0007446 0 1.6 0.605 0.731 166791 G protein-coupled receptor 86 IncytePD:1782488 Hs.13040 GPR86 3q24

611 0.0007518 0.002 0.879 1.66 1.548 160764 F-box only protein 7 IncytePD:1911835 Hs.5912 FBXO7 22q12-q13

612 0.000754 5e-04 0.475 1.295 1.172 166123 glypican 4 IncytePD:2182642 Hs.58367 GPC4 Xq26.1 613 0.0007579 0 1.65 2.38 3.118 162113 destrin (actin depolymerizing

factor) IncytePD:2062011 Hs.408576 DSTN 20p11.23

614 0.0007583 0 0.555 1.036 0.73 169700 gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)

IncytePD:1830640 Hs.82963 GNRH1 8p21-p11.2

615 0.0007648 5e-04 1.604 1.293 1.091 169017 hypothetical protein LOC220988 IncytePD:1929355 Hs.249247 LOC220988 2q31.2 616 0.0007672 5e-04 1.3 6.887 4.068 165842 four and a half LIM domains 1 IncytePD:224996 Hs.239069 FHL1 Xq26 617 0.000771 0.001 0.551 0.864 0.384 168380 TBC1 domain family, member 4 IncytePD:924189 Hs.173802 TBC1D4 13q21.33 618 0.0007757 0 0.221 0.714 0.636 168539 hypothetical protein FLJ21127 IncytePD:1996522 Hs.382368 FLJ21127 12q24.11 619 0.0007779 5e-04 0.312 0.496 0.557 164087 Homo sapiens cDNA FLJ13432

620 0.0007823 0.002 1.365 1.793 1.911 164798 hypothetical protein PRO1580 IncytePD:2842526 Hs.270863 PRO1580 5q31.3 621 0.0007921 0.0015 1.972 1.565 1.145 163166 hypothetical protein FLJ20425 IncytePD:2233551 Hs.425427 LYAR 4p16.2 622 0.0007973 0 1.082 1.837 2.156 167050 Homo sapiens, clone

623 0.0007973 0.001 0.441 1.025 0.768 160949 Vam6/Vps39-like IncytePD:1674319 Hs.9452 VPS39 15q14 624 0.0007986 0.001 1.488 0.68 0.944 164667 Homo sapiens, clone

625 0.000801 5e-04 1.235 1.407 0.949 167733 complement component 3a receptor 1

IncytePD:1995864 Hs.155935 C3AR1 12p13.31

626 0.0008076 0.001 1.606 1.157 1.077 168251 activator of basal transcription 1 IncytePD:1996818 Hs.109428 ABT1 6p21.33 627 0.0008173 0 0.303 0.381 0.774 164581 retinol dehydrogenase 10 (all-trans) IncytePD:2506090 Hs.432987 RDH10 8q13.2 628 0.000818 0.001 0.355 0.85 0.896 164003 MGC16028 similar to RIKEN

cDNA 1700019E19 gene IncytePD:2367207 Hs.8984 MGC16028 14q24.2

629 0.00082 0 0.26 0.481 0.89 165308 ESTs IncytePD:201053 Hs.245997 21 630 0.0008298 0 1.755 0.693 0.953 163226 mannan-binding lectin serine

protease 2 IncytePD:2513394 Hs.119983 MASP2 1p36.3-

p36.2 631 0.0008317 0.0015 2.986 1.582 5.208 160756 glutathione peroxidase 2

(gastrointestinal) IncytePD:1633118 Hs.2704 GPX2 14q24.1

632 0.0008323 0.001 1.147 0.73 0.821 161387 hypothetical protein MGC46341 IncytePD:3729130 Hs.34665 MGC46341 6q22.31 633 0.0008331 0 0.724 1.484 1.368 166596 Incyte EST IncytePD:1376090 634 0.0008363 0.001 0.955 1.503 1.131 169595 eukaryotic translation initiation

factor 4A, isoform 2 IncytePD:2060081

635 0.0008404 0 0.63 1.218 1.587 161410 KIAA0672 gene product IncytePD:2769881 Hs.6336 KIAA0672 17p12 636 0.0008498 0 0.769 0.234 0.711 161587 kallikrein 8 (neuropsin/ovasin) IncytePD:2604309 Hs.104570 KLK8 19q13.3-

q13.4 637 0.0008505 0 1.692 2.134 1.038 165894 protein kinase, cAMP-dependent,

regulatory, type II, beta IncytePD:1968465 Hs.77439 PRKAR2B 7q22-

q31.1 638 0.0008525 5e-04 1.374 2.134 1.503 159953 glyceronephosphate O- IncytePD:3600267 Hs.12482 GNPAT 1q42.11-

acyltransferase 42.3 639 0.000853 0.0015 9.873 2.249 4.505 164126 Homo sapiens cDNA: FLJ21962

fis, clone HEP05564. IncytePD:2507593 Hs.7567 12

640 0.0008545 0 7.451 2.33 5.781 166171 Homo sapiens cDNA FLJ14241 fis, clone OVARC1000533.

IncytePD:2082211 Hs.183765 19

641 0.0008613 0.001 1.477 0.672 0.897 167508 corticotropin releasing hormone receptor 1

IncytePD:2494107 Hs.79117 CRHR1 17q12-q22

642 0.0008646 0.001 0.614 0.969 0.807 160448 oral-facial-digital syndrome 1 IncytePD:2080379 Hs.6483 OFD1 Xp22.2-p22.3

643 0.0008681 0.0015 1.099 0.786 0.607 166255 lymphocyte antigen 64 homolog, radioprotective 105kDa (mouse)

IncytePD:410370 Hs.87205 LY64 5q12

644 0.000869 5e-04 1.438 1.533 1.042 160299 KIAA0117 protein IncytePD:1238619 645 0.0008734 5e-04 0.68 1.025 1.019 164427 KIAA1395 protein IncytePD:1506055 Hs.8982 KIAA1395 19p13.2 646 0.0008839 0.0025 0.86 1.24 1.009 161805 spindlin-like protein 2 IncytePD:2522604 Hs.82577 SPIN2 Xp11.23-

p11.21 647 0.0008881 5e-04 1.548 3.749 3.777 166420 tubulin, beta, 5 IncytePD:1486358 Hs.110837 TUBB5 19p13.3 648 0.0008888 5e-04 0.776 1.144 1.153 163837 death associated transcription

factor 1 IncytePD:1655225 Hs.155313 DATF1 20q13.33

649 0.0008932 0 0.759 0.503 1.206 160113 coagulation factor II (thrombin) receptor-like 1

IncytePD:1801553 Hs.154299 F2RL1 5q13

650 0.0009014 5e-04 0.688 0.414 0.371 165607 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome

IncytePD:1852849 Hs.13980 UTX Xp11.2

651 0.0009014 0.001 1.603 0.774 0.946 165094 mitogen-activated protein kinase kinase kinase 10

IncytePD:2155126 Hs.30223 MAP3K10 19q13.2

652 0.0009054 0.0025 0.23 0.472 0.575 165420 insulin receptor tyrosine kinase substrate

IncytePD:1843971 Hs.23449 LOC55971 7q21.3

653 0.0009136 0 1.735 0.572 0.929 161357 interleukin 11 IncytePD:3138407 Hs.1721 IL11 19q13.3-q13.4

654 0.0009169 5e-04 0.749 0.933 1.104 160045 platelet-activating factor acetylhydrolase 2, 40kDa

IncytePD:3292380 Hs.234392 PAFAH2 1p34.3

655 0.0009265 0 1.124 0.633 0.769 161349 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

IncytePD:2640749 Hs.406 SLC6A3 5p15.3

656 0.0009334 5e-04 1.62 1.485 1.173 166921 peptide-histidine transporter 4 IncytePD:380220 Hs.355660 PTR4 12q24.32 657 0.0009351 0.001 1.787 2.386 2.633 165547 dihydrolipoamide S-

succinyltransferase (E2 component of 2-oxo-glutarate complex)

IncytePD:1830335

658 0.0009394 0 0.373 0.601 0.837 165644 KIAA0014 gene product IncytePD:1952480 Hs.155650 KIAA0014 8q24.3 659 0.0009395 0 0.854 1.177 1.136 164257 hypothetical protein FLJ20699 IncytePD:1655377 Hs.15125 FLJ20699 22q13 660 0.0009532 0.0015 0.492 0.598 1.135 167120 stomatin IncytePD:1853229 Hs.160483 STOM 9q34.1

661 0.0009536 0 0.768 1.853 2.045 162899 K562 cell-derived leucine-zipper-like protein 1

IncytePD:1405352 Hs.31854 KLP1 19q13.42

662 0.000956 5e-04 1.871 0.857 1.272 168437 KIAA0843 protein IncytePD:958330 Hs.26777 KIAA0843 5q32 663 0.0009736 0 0.446 1.133 0.851 161406 Incyte EST IncytePD:2720976 664 0.0009854 0.0015 0.879 0.368 0.534 161553 basic leucine zipper nuclear factor

1 (JEM-1) IncytePD:2459178 Hs.158205 BLZF1 1q24

665 0.0009868 0.002 0.824 0.409 0.627 168103 Homo sapiens cDNA FLJ23705 fis, clone HEP11066.

IncytePD:2105590 Hs.49136 8

666 0.0009899 0 1.732 0.732 0.985 168651 inositol hexaphosphate kinase 1 IncytePD:546517 Hs.74579 IHPK1 3p21.31 667 0.0009938 0 0.675 0.369 0.21 160235 aryl-hydrocarbon receptor nuclear

translocator 2 IncytePD:2113238 Hs.6111 ARNT2 15q24

668 0.0009962 0.001 0.828 1.178 1.089 162554 aquaporin 7 IncytePD:2304391 Hs.25475 AQP7 9p13 669 0.0009964 0.002 0.576 0.356 0.779 162736 Ste20-related serine/threonine

kinase IncytePD:1968259 Hs.105751 SLK 10q24.32

670 0.0009971 0.001 0.116 0.311 0.324 167045 chemokine (C-X3-C motif) ligand 1

IncytePD:1728607 Hs.80420 CX3CL1 16q13

Supplemental Table 2 List of genes differentially expressed in normal nasopharyngeal epithelium (N) and carcinoma (T). Parametric

p-value Fold

difference of

geometric means (T vs N)

Description UG cluster

Gene symbol

p < 1e-07 0.019 trefoil factor 3 (intestinal) Hs.82961 TFF3 21q22.3 p < 1e-07 0.023 secretory leukocyte protease inhibitor

(antileukoproteinase) Hs.251754 SLPI 20q12

3.2e-06 0.023 tetraspan 1 Hs.38972 TSPAN-1 1p33 p < 1e-07 0.038 prominin-like 1 (mouse) Hs.112360 PROML1 4p15.33 2.24e-05 0.039 forkhead box J1 Hs.93974 FOXJ1 17q22-

17q25 p < 1e-07 0.043 polymeric immunoglobulin receptor Hs.205126 PIGR 1q31-q41 p < 1e-07 0.061 selenium binding protein 1 Hs.334841 SELENBP1 1q21-q22 0.0003566 0.061 serine (or cysteine) proteinase inhibitor,

clade B (ovalbumin), member 3 Hs.227948 SERPINB3 18q21.3

p < 1e-07 0.067 sodium channel, nonvoltage-gated 1 alpha Hs.446415 SCNN1A 12p13 3.2e-06 0.072 mucin 1, transmembrane Hs.89603 MUC1 1q21 3.5e-06 0.072 serum amyloid A4, constitutive Hs.1955 SAA4 11p15.1-

p14 4.1e-06 0.072 Ras-related associated with diabetes Hs.1027 RRAD 16q22 9.7e-06 0.076 non-metastatic cells 5, protein expressed in

(nucleoside-diphosphate kinase) Hs.72050 NME5 5q31

p < 1e-07 0.077 B-factor, properdin Hs.69771 BF 6p21.3 p < 1e-07 0.079 Wilms tumor associated protein Hs.251573 WIT-1 11p13 1.92e-05 0.079 sperm associated antigen 6 Hs.158213 SPAG6 10p12.2 3e-07 0.081 carcinoembryonic antigen-related cell

adhesion molecule 6 (non-specific cross reacting antigen)

Hs.73848 CEACAM6 19q13.2

1e-07 0.082 dynein, axonemal, light intermediate polypeptide 1

Hs.406050 DNALI1 1p35.1

3e-07 0.083 carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Hs.76688 CES1 16q13-q22.1

3e-07 0.083 solute carrier family 22 (organic cation transporter), member 4

Hs.77239 SLC22A4 5q31.1

1.05e-05 0.083 aldehyde dehydrogenase 1 family, member A1

Hs.76392 ALDH1A1 9q21.13

7.06e-05 0.09 BRCA1 associated protein Hs.122764 BRAP 12q24 4.88e-05 0.096 connective tissue growth factor Hs.75511 CTGF 6q23.1 0.0007428 0.096 matrix metalloproteinase 10 (stromelysin 2) Hs.2258 MMP10 11q22.3 2e-07 0.097 S100 calcium binding protein P Hs.2962 S100P 4p16 1.6e-06 0.102 B7 protein Hs.155586 B7 12p13 1e-06 0.116 regulatory factor X, 2 (influences HLA class

II expression) Hs.100007 RFX2 19p13.3-

p13.2 1e-07 0.121 monoglyceride lipase Hs.6721 MGLL 3q21.3 1e-07 0.124 retinoic acid receptor responder (tazarotene

induced) 1 Hs.82547 RARRES1 3q25.32

6.7e-05 0.124 B-cell CLL/lymphoma 3 Hs.31210 BCL3 19q13.1-q13.2

0.0004344 0.128 lactotransferrin Hs.105938 LTF 3q21-q23 0.0002531 0.129 ATPase, Class V, type 10B Hs.109358 ATP10B 5q34 3e-06 0.136 Hermansky-Pudlak syndrome 3 Hs.282804 HPS3 3q24 1.4e-05 0.138 claudin 10 Hs.26126 CLDN10 13q31-

q34 3e-07 0.139 solute carrier family 27 (fatty acid

transporter), member 2 Hs.11729 SLC27A2 15q21.2

0.000223 0.145 profilin 2 Hs.91747 PFN2 3q25.1-q25.2

5e-07 0.146 likely ortholog of mouse tumor necrosis-alpha-induced adipose-related protein

Hs.44208 FLJ23153 7q21.12

0.000446 0.147 glutathione S-transferase A3 Hs.102484 GSTA3 6p12.1 0.0001045 0.148 melanoma inhibitory activity Hs.279651 MIA 19q13.32-

q13.33 8.07e-05 0.149 complement component 3 Hs.284394 C3 19p13.3-

p13.2 0.0005125 0.151 zinc finger protein 76 (expressed in testis) Hs.29222 ZNF76 6p21.3-

1.9e-06 0.152 amylase, alpha 2B; pancreatic Hs.335493 AMY2B 1p21 2.7e-06 0.152 ribonuclease, RNase A family, 4 Hs.283749 RNASE4 14q11.1 1.56e-05 0.152 sperm associated antigen 8 Hs.256747 SPAG8 9p13.3 1.02e-05 0.153 ARF protein Hs.264509 LOC51326 17q21.31 1.2e-06 0.158 aldehyde dehydrogenase 3 family, member

B1 Hs.83155 ALDH3B1 11q13

5.17e-05 0.159 dynein, axonemal, heavy polypeptide 9 Hs.284259 DNAH9 17p12 p < 1e-07 0.160 transferrin Hs.396489 TF 3q21 0.0001652 0.160 solute carrier family 26, member 4 Hs.159275 SLC26A4 7q31 3.99e-05 0.168 complement component 4A Hs.170250 C4A 6p21.3 5.7e-06 0.171 coagulation factor III (thromboplastin, tissue

factor) Hs.62192 F3 1p22-p21

5.1e-06 0.179 ceruloplasmin (ferroxidase) Hs.296634 CP 3q23-q25 1e-07 0.182 nei endonuclease VIII-like 1 (E. coli) Hs.28355 NEIL1 15q22.33 5.05e-05 0.182 ectonucleotide

pyrophosphatase/phosphodiesterase 3 Hs.264750 ENPP3 6q22

0.0007193 0.183 tumor-associated calcium signal transducer 2

Hs.23582 TACSTD2 1p32-p31

0.0001429 0.186 argininosuccinate synthetase Hs.160786 ASS 9q34.1 2e-07 0.187 zinc finger protein 204 Hs.8198 ZNF204 6p21.3 7e-07 0.188 cytochrome P450, family 2, subfamily J,

polypeptide 2 Hs.152096 CYP2J2 1p31.3-

p31.2 0.0001697 0.189 leukocyte immunoglobulin-like receptor,

subfamily B (with TM and ITIM domains), member 5

Hs.77062 LILRB5 19q13.4

0.0001979 0.189 centrin, EF-hand protein, 2 Hs.82794 CETN2 Xq28 9.31e-05 0.197 vanin 1 Hs.12114 VNN1 6q23-q24 2e-06 0.198 Arg/Abl-interacting protein ArgBP2 Hs.379795 ARGBP2 4q35.1 8.5e-06 0.198 anterior gradient 2 homolog (Xenepus

laevis) Hs.413945 AGR2 7p21.3

8.7e-05 0.198 EBNA1 binding protein 2 Hs.346868 EBNA1BP2 1p35-p33 7e-06 0.200 flavin containing monooxygenase 2 Hs.132821 FMO2 1q23-q25 0.000255 0.203 selenoprotein P, plasma, 1 Hs.275775 SEPP1 5q31 1e-07 0.204 Meis1, myeloid ecotropic viral integration

site 1 homolog 3 (mouse) Hs.380923 MEIS3 17p11.2

1e-06 0.204 mutated in colorectal cancers Hs.1345 MCC 5q21-q22 5.6e-06 0.204 epidermal growth factor receptor pathway

substrate 8 Hs.2132 EPS8 12q23-

q24 6.54e-05 0.204 ESTs Hs.432503 1 7.59e-05 0.204 nucleobindin 2 Hs.3164 NUCB2 11p15.1-

p14 0.0002293 0.211 benzodiazapine receptor (peripheral)

associated protein 1 Hs.112499 BZRAP1 17q22-

q23 1.8e-06 0.212 inhibin, beta B (activin AB beta polypeptide) Hs.1735 INHBB 2cen-q13 1.21e-05 0.212 transforming growth factor, beta receptor III

(betaglycan, 300kDa) Hs.342874 TGFBR3 1p33-p32

8.92e-05 0.213 UDP glycosyltransferase 1 family, polypeptide A1

Hs.278896 UGT1A1 2q37

3.16e-05 0.215 myosin ID Hs.39871 MYO1D 17q11-q12

3.66e-05 0.216 tripartite motif-containing 2 Hs.12372 TRIM2 4q31.23 0.0001515 0.217 CDP-diacylglycerol synthase

(phosphatidate cytidylyltransferase) 1 Hs.152981 CDS1 4q21.23

1.3e-06 0.218 Meis1, myeloid ecotropic viral integration site 1 homolog (mouse)

Hs.170177 MEIS1 2p14-p13

7.87e-05 0.224 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)

Hs.75106 CLU 8p21-p12

5e-07 0.225 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6

Hs.41072 SERPINB6 6p25

4.22e-05 0.225 protein S (alpha) Hs.64016 PROS1 3p11-q11.2

3.3e-06 0.226 protein tyrosine phosphatase, receptor type, U

Hs.19718 PTPRU 1p35.3-p35.1

5.07e-05 0.226 spermidine/spermine N1-acetyltransferase Hs.28491 SAT Xp22.1 2.14e-05 0.232 calcium channel, voltage-dependent,

gamma subunit 3 Hs.7235 CACNG3 16p12-

p13.1 4.92e-05 0.234 oxysterol binding protein-like 6 Hs.318775 OSBPL6 2q31-

q32.1 4.3e-06 0.235 serum-inducible kinase Hs.3838 SNK 5q12.1-

q13.2 2e-07 0.237 calmin (calponin-like, transmembrane) Hs.406099 CLMN 14q32.2 0.0006142 0.240 actin binding LIM protein 1 Hs.158203 ABLIM1 10q25 1.6e-06 0.241 E74-like factor 3 (ets domain transcription

factor, epithelial-specific ) Hs.166096 ELF3 1q32.2

4.5e-06 0.241 mucin 5, subtype B, tracheobronchial Hs.102482 MUC5B 11p15 9.69e-05 0.242 serine/threonine kinase with Dbl- and

pleckstrin homology domains Hs.162189 TRAD 3q21.2

0.0001639 0.243 protein tyrosine phosphatase, receptor- Hs.78867 PTPRZ1 7q31.3

type, Z polypeptide 1 3.06e-05 0.247 hypothetical protein FLJ20535 Hs.183362 FLJ20535 11q23.2 0.0001089 0.248 oxytocin receptor Hs.2820 OXTR 3p25 3.78e-05 0.249 axin 2 (conductin, axil) Hs.127337 AXIN2 17q23-

q24 8.32e-05 0.253 retinoic acid induced 3 Hs.194691 RAI3 12p13-

p12.3 p < 1e-07 0.256 keratin 7 Hs.23881 KRT7 12q12-

q13 1.76e-05 0.257 KIAA1244 protein Hs.194408 KIAA1244 6q23.3 1.4e-06 0.259 kinesin family member 13B Hs.15711 KIF13B 8p12 3e-07 0.261 HRAS-like suppressor 3 Hs.37189 HRASLS3 11q12.3 0.0005251 0.263 nebulette Hs.5025 NEBL 10p12 0.0008438 0.264 tubulin, beta polypeptide Hs.336780 TUBB 6p21.3 3.71e-05 0.265 cytidine monophosphate-N-

acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase)

Hs.24697 CMAH 6p21.32

0.0001682 0.268 24-dehydrocholesterol reductase Hs.75616 DHCR24 1p33-p31.1

9.1e-06 0.273 microphthalmia-associated transcription factor

Hs.166017 MITF 3p14.1-p12.3

0.0004284 0.273 apolipoprotein L, 1 Hs.114309 APOL1 22q13.1 6.5e-06 0.274 calcium channel, voltage-dependent, beta 3

subunit Hs.250712 CACNB3 12q13

0.0003573 0.277 KIAA1377 protein Hs.188790 KIAA1377 11q22.1 3e-07 0.279 hypothetical protein FLJ21827 Hs.334360 FLJ21827 11q23.3 0.0001037 0.279 cysteine-rich protein 2 Hs.70327 CRIP2 14q32.3 2.1e-06 0.284 hypothetical protein LOC283445 Hs.234898 LOC283445 12q24.12 0.0001683 0.285 calcium and integrin binding 1 (calmyrin) Hs.10803 CIB1 15q25.3-

q26 0.0005307 0.285 myeloid differentiation primary response

gene (88) Hs.82116 MYD88 3p22

2.6e-06 0.287 lipidosin Hs.277543 BG1 15q23-q24

7e-07 0.288 LIM domain only 2 (rhombotin-like 1) Hs.184585 LMO2 11p13 8.62e-05 0.289 transmembrane 4 superfamily member 6 Hs.121068 TM4SF6 Xq22 0.0001426 0.289 KIAA0284 protein Hs.182536 KIAA0284 14q32.33 2.7e-06 0.29 galactosamine (N-acetyl)-6-sulfate sulfatase

(Morquio syndrome, mucopolysaccharidosis type IVA)

Hs.159479 GALNS 16q24.3

1.77e-05 0.290 pregnancy-zone protein Hs.74094 PZP 12p13-p12.2

4.58e-05 0.291 Homo sapiens cDNA FLJ20115 fis, clone COL05594

1.7e-06 0.292 iduronate 2-sulfatase (Hunter syndrome) Hs.172458 IDS Xq28 7.4e-05 0.293 short-chain dehydrogenase/reductase 1 Hs.17144 SDR1 1p36.1 0.0007378 0.293 claudin 7 Hs.278562 CLDN7 17p13 3.74e-05 0.294 zinc finger protein 91 homolog (mouse) Hs.46366 ZFP91 11q12 2e-07 0.295 family with sequence similarity 13, member

A1 Hs.177664 FAM13A1 4q22.1

3.3e-06 0.295 keratin 7 Hs.23881 KRT7 12q12-q13

1.53e-05 0.296 B/K protein Hs.26971 LOC51760 16p13.11 8e-07 0.299 hypothetical protein FLJ13942 Hs.20537 FLJ13942 6q22.31 1.06e-05 0.301 phosphodiesterase 8B Hs.78106 PDE8B 5q13.2 8.39e-05 0.303 tetraspan 2 Hs.234863 TSPAN-2 1p12 7.48e-05 0.307 v-erb-b2 erythroblastic leukemia viral

oncogene homolog 3 (avian) Hs.199067 ERBB3 12q13

6.13e-05 0.308 echinoderm microtubule associated protein like 1

Hs.12451 EML1 14q32

0.000271 0.312 transcobalamin I (vitamin B12 binding protein, R binder family)

Hs.2012 TCN1 11q11-q12

0.0009395 0.312 dynein, axonemal, light polypeptide 4 Hs.182595 DNAL4 22q13.1 6.16e-05 0.314 EphA2 Hs.171596 EPHA2 1p36 3.14e-05 0.317 cystic fibrosis transmembrane conductance

regulator, ATP-binding cassette (sub-family C, member 7)

Hs.426266 CFTR 7q31.2

0.0005052 0.317 CGI-43 protein 1.6e-06 0.319 histidine decarboxylase Hs.1481 HDC 15q21-

q22 5.19e-05 0.320 PTH-responsive osteosarcoma B1 protein Hs.79340 B1 7p14 2.26e-05 0.321 Rho GTPase-activating protein Hs.111138 RICS 11q24-

q25 0.0006524 0.321 monoamine oxidase A Hs.183109 MAOA Xp11.4-

p11.3 0.0002195 0.323 Mdm2, transformed 3T3 cell double minute

2, p53 binding protein (mouse) Hs.170027 MDM2 12q14.3-

q15 1.7e-05 0.326 dihydropyrimidinase-like 3 Hs.74566 DPYSL3 5q32 1.73e-05 0.326 FLJ00005 protein Hs.367690 FLJ00005 15q22.33 0.0001882 0.326 paraneoplastic antigen MA1 Hs.194709 PNMA1 14q24.1

0.0001697 0.328 Duffy blood group Hs.183 FY 1q21-q22 1.3e-06 0.330 Fanconi anemia, complementation group A 1.34e-05 0.330 hypothetical protein FLJ20375 Hs.274251 FLJ20375 9p21 0.0001764 0.333 asparaginase like 1 Hs.7331 ASRGL1 11q12.2 0.0001929 0.333 IK cytokine, down-regulator of HLA II Hs.8024 IK 5q31.3 5.59e-05 0.335 hypothetical protein FLJ32029 Hs.26612 FLJ32029 11q13.3 5.64e-05 0.338 adenylyl cyclase-associated protein 2 Hs.296341 CAP2 6p22.3 1e-07 0.339 epidermal growth factor receptor pathway

substrate 8-related protein 1 Hs.28907 EPS8R1 19q13.42

0.0001958 0.339 Probe hTg737 (polycystic kidney disease, autosomal recessive)

Hs.2291 TG737 13q12.1

0.0006412 0.343 carnitine deficiency-associated gene expressed in ventricle 1

Hs.333120 CDV-1 12q24.13

5.14e-05 0.344 macrophage stimulating, pseudogene 9 Hs.278657 MSTP9 1p36.13 p < 1e-07 0.347 emerin (Emery-Dreifuss muscular

dystrophy) Hs.2985 EMD Xq28

5.07e-05 0.347 DKFZP586A0522 protein Hs.288771 DKFZP586A052 12q13.12 0.0003466 0.347 ATP-binding cassette, sub-family C

(CFTR/MRP), member 6 Hs.274260 ABCC6 16p13.1

0.0006825 0.349 3-hydroxybutyrate dehydrogenase (heart, mitochondrial)

Hs.76893 BDH 3q29

0.0008888 0.349 interferon-stimulated transcription factor 3, gamma 48kDa

Hs.1706 ISGF3G 14q11.2

0.0008012 0.350 interleukin 1 receptor, type I Hs.82112 IL1R1 2q12 2.42e-05 0.351 microphthalmia-associated transcription

factor Hs.166017 MITF 3p14.1-

p12.3 0.0004684 0.351 putative ankyrin-repeat containing protein Hs.4996 DKFZP564D166 17q23.3 8.48e-05 0.353 dihydropyrimidine dehydrogenase Hs.1602 DPYD 1p22 0.0004017 0.355 synaptotagmin-like 2 Hs.92254 SYTL2 11q14 0.0004607 0.355 transforming growth factor beta-stimulated

protein TSC-22 Hs.114360 TSC22 13q14

0.0002809 0.356 LIM domain only 7 Hs.5978 LMO7 13q21.33 0.0001931 0.357 sushi-repeat protein Hs.126782 SRPUL Xq21.33-

q23 0.0009998 0.358 Homo sapiens colon cancer antigen NY-

CO-45 mRNA, partial cds Hs.160881 6

3.3e-06 0.360 B-cell CLL/lymphoma 6 (zinc finger protein 51)

Hs.155024 BCL6 3q27

4.7e-05 0.361 putative ankyrin-repeat containing protein Hs.4996 DKFZP564D166 17q23.3 1.48e-05 0.364 apolipoprotein D Hs.75736 APOD 3q26.2-

qter 3.03e-05 0.364 Bernardinelli-Seip congenital lipodystrophy

2 (seipin) Hs.293981 BSCL2 11q12-

q13.5 6e-07 0.365 truncated calcium binding protein Hs.351621 LOC51149 5q35.3 0.0001505 0.367 arachidonate 15-lipoxygenase Hs.73809 ALOX15 17p13.3 0.0004278 0.367 Kruppel-like factor 4 (gut) Hs.356370 KLF4 9q31 0.0001075 0.368 RNA binding protein with multiple splicing Hs.80248 RBPMS 8p12-p11 1.94e-05 0.369 collagen, type VIII, alpha 1 Hs.114599 COL8A1 3q12-

q13.1 0.0006642 0.369 midline 1 (Opitz/BBB syndrome) Hs.27695 MID1 Xp22 9.64e-05 0.370 oxysterol binding protein-like 5 Hs.112034 OSBPL5 11p15.4 8.21e-05 0.371 nei like 2 (E. coli) Hs.293818 NEIL2 8 0.0009131 0.375 bone morphogenetic protein 1 Hs.1274 BMP1 8p21 0.0001143 0.376 EGF-containing fibulin-like extracellular

matrix protein 2 Hs.6059 EFEMP2 11q13

4.29e-05 0.378 carboxylesterase 2 (intestine, liver) Hs.282975 CES2 16q21 7.5e-06 0.380 two-pore channel 1, homolog Hs.26440 KIAA1169 12q24.21 0.0002229 0.380 caspase 10, apoptosis-related cysteine

protease Hs.5353 CASP10 2q33-q34

0.000353 0.380 target of myb1 (chicken) Hs.9482 TOM1 22q13.1 3e-07 0.388 Rho-related BTB domain containing 1 Hs.15099 RHOBTB1 10q21.2 0.0001706 0.389 aldehyde dehydrogenase 3 family, member

A2 Hs.159608 ALDH3A2 17p11.2

0.0001326 0.391 insulin receptor Hs.89695 INSR 19p13.3-p13.2

0.0001366 0.391 retinol dehydrogenase 10 (all-trans) Hs.432987 RDH10 8q13.2 0.0008671 0.391 C-terminal binding protein 2 Hs.171391 CTBP2 10q26.2 5.5e-05 0.393 TBP-interacting protein Hs.154740 TIP120B 3p25.1 0.0002542 0.393 calpastatin Hs.359682 CAST 5q15-q21 0.000646 0.393 solute carrier family 13 (sodium-dependent

dicarboxylate transporter), member 2 Hs.102307 SLC13A2 17p11.1-

q11.1 0.0006831 0.393 period homolog 3 (Drosophila) Hs.12592 PER3 1p36.22 0.0002168 0.394 calpain 3, (p94) Hs.293267 CAPN3 15q15.1-

q21.1 6.7e-06 0.395 multiple PDZ domain protein Hs.169378 MPDZ 9p24-p22 2.84e-05 0.395 cytochrome P450, family 4, subfamily F,

polypeptide 12 Hs.180570 CYP4F12 19p13.1

0.00051 0.395 galactosylceramidase (Krabbe disease) Hs.273 GALC 14q31 1.49e-05 0.397 v-ral simian leukemia viral oncogene

homolog B (ras related; GTP binding Hs.348024 RALB 2cen-q13

protein) 0.0001103 0.398 kallikrein 10 Hs.69423 KLK10 19q13.3-

q13.4 0.0001117 0.399 ectonucleoside triphosphate

diphosphohydrolase 1 Hs.205353 ENTPD1 10q24

0.0004262 0.404 cyclin A1 Hs.79378 CCNA1 13q12.3-q13

p < 1e-07 0.406 galactose-4-epimerase, UDP- Hs.76057 GALE 1p36-p35 0.0009213 0.406 prostate stem cell antigen Hs.423634 PSCA 8q24.2 0.0001428 0.407 quiescin Q6 Hs.77266 QSCN6 1q24 1e-06 0.412 hypothetical protein DKFZp434M0331 Hs.48219 DKFZp434M033 12q23.2 0.0009066 0.417 cytochrome P450, family 24, subfamily A,

polypeptide 1 Hs.89663 CYP24A1 20q13

9.3e-05 0.418 calpastatin Hs.359682 CAST 5q15-q21 3.01e-05 0.419 RAB, member of RAS oncogene family-like

4 Hs.50267 RABL4 22q13.1

0.0008733 0.419 transmembrane protease, serine 2 Hs.318545 TMPRSS2 21q22.3 5.22e-05 0.422 meningioma expressed antigen 6 (coiled-

coil proline-rich) Hs.117242 MGEA6 14q

0.0001665 0.423 thyroid hormone receptor-associated protein (100 kDa)

Hs.23106 TRAP100 17q21.1

1.4e-06 0.426 complement component 5 receptor 1 (C5a ligand)

Hs.2161 C5R1 19q13.3-q13.4

3.1e-06 0.432 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

Hs.332173 TLE2 19p13.3

0.0006789 0.435 rTS beta protein Hs.180433 HSRTSBETA 18p11.32 0.0002934 0.437 potassium voltage-gated channel, delayed-

rectifier, subfamily S, member 3 Hs.47584 KCNS3 2p24

5.08e-05 0.439 synaptopodin Hs.5307 KIAA1029 5q33.1 5.6e-06 0.445 FK506 binding protein 1B, 12.6 kDa Hs.77643 FKBP1B 2p24.1 1.17e-05 0.445 tropomyosin 4 Hs.250641 TPM4 19p13.1 0.0003825 0.446 melanoma antigen, family D, 2 Hs.4943 MAGED2 Xp11.4-

p11.1 0.0004562 0.446 KIAA0014 gene product Hs.155650 KIAA0014 8q24.3 0.0001017 0.447 meningioma expressed antigen 6 (coiled-

coil proline-rich) Hs.117242 MGEA6 14q

0.0001431 0.448 loss of heterozygosity, 11, chromosomal region 2, gene A

Hs.152944 LOH11CR2A 11q23

0.0008466 0.449 trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)

8.68e-05 0.450 retinitis pigmentosa GTPase regulator Hs.153614 RPGR Xp11.4 3.47e-05 0.452 kallikrein B, plasma (Fletcher factor) 1 Hs.1901 KLKB1 4q34-q35 0.0006569 0.452 SWI/SNF related, matrix associated, actin

dependent regulator of chromatin, subfamily d, member 3

Hs.71622 SMARCD3 7q35-q36

7.65e-05 0.453 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)

Hs.271923 GALNT4 12q21.3-q22

3.37e-05 0.459 numb homolog (Drosophila) Hs.78890 NUMB 14q24.3 8.46e-05 0.459 single stranded DNA binding protein 4 Hs.324618 SSBP4 19p13.1 0.0001728 0.460 hypothetical protein FLJ20477 Hs.26994 FLJ20477 1p35.3 6.7e-06 0.467 calponin 1, basic, smooth muscle Hs.21223 CNN1 19p13.2-

p13.1 2.55e-05 0.467 paired box gene 2 Hs.155644 PAX2 10q22.1-

q24.3 0.0004307 0.472 tumor protein p53 binding protein, 1 Hs.170263 TP53BP1 15q15-

q21 0.0001085 0.476 growth arrest-specific 8 Hs.54877 GAS8 16q24.3 0.0008631 0.476 guanylate binding protein 1, interferon-

inducible, 67kDa Hs.62661 GBP1 1p22.2

1.34e-05 0.479 mannose-6-phosphate receptor (cation dependent)

Hs.134084 M6PR 12p13

0.0001916 0.488 ATP synthase mitochondrial F1 complex assembly factor 2

Hs.13434 ATPAF2 17

0.0005857 0.491 cyclin-dependent kinase (CDC2-like) 10 Hs.77313 CDK10 16q24 3e-05 0.493 angiogenin, ribonuclease, RNase A family,

5 Hs.332764 ANG 14q11.1-

q11.2 2.8e-05 0.495 zinc finger protein 135 (clone pHZ-17) Hs.374293 ZNF135 19q13.4 2.6e-06 0.498 acylphosphatase 1, erythrocyte (common)

type Hs.18573 ACYP1 14q24.3

7.79e-05 0.499 phytanoyl-CoA hydroxylase (Refsum disease)

Hs.172887 PHYH 10pter-p11.2

8.6e-05 0.504 defensin, beta 1 Hs.32949 DEFB1 8p23.2-p23.1

0.0009802 0.508 histone deacetylase 7A Hs.275438 HDAC7A 12q13.1 7.53e-05 0.509 hypothetical protein BC010682 Hs.4896 LOC90550 10q22.2 0.0003743 0.509 argininosuccinate lyase Hs.61258 ASL 7cen-

q11.2 2.39e-05 0.510 D-aspartate oxidase Hs.174441 DDO 6q21

0.0001004 0.511 receptor (calcitonin) activity modifying protein 2

Hs.155106 RAMP2 17q12-q21.1

6.48e-05 0.515 period homolog 2 (Drosophila) Hs.153405 PER2 2q37.3 2.59e-05 0.517 hypothetical protein LOC284001 Hs.122075 LOC284001 17q25.3 0.0007328 0.519 regulatory factor X, 3 (influences HLA class

II expression) Hs.166019 RFX3 9p24.2

2.16e-05 0.521 DKFZP586P0123 protein Hs.376803 DKFZP586P012 11q13.3 0.0001128 0.524 lecithin-cholesterol acyltransferase 6.47e-05 0.527 protein kinase C, zeta Hs.78793 PRKCZ 1p36.33-

p36.2 0.0008399 0.527 P450 (cytochrome) oxidoreductase Hs.167246 POR 7q11.2 5.53e-05 0.529 hypothetical protein GL012 Hs.21379 GL012 9q34.11 0.0004421 0.529 destrin (actin depolymerizing factor) Hs.408576 DSTN 20p11.23 0.0006846 0.535 Homo sapiens mRNA; cDNA

DKFZp762N156 (from clone DKFZp762N156)

Hs.194397 7

0.0002133 0.539 nephronophthisis 4 Hs.106487 NPHP4 1p36.22 0.0001369 0.542 UDP-N-acteylglucosamine

pyrophosphorylase 1 Hs.21293 UAP1 1q23.1

5.9e-06 0.544 Homo sapiens, Similar to hypothetical protein FLJ13639, clone IMAGE:4310637, mRNA

Hs.390401 13

0.0002787 0.547 HLA-B associated transcript 3 Hs.274348 BAT3 6p21.3 0.0003082 0.553 ALFY Hs.198135 ALFY 4q21.3 0.0003101 0.553 Homo sapiens cDNA FLJ30301 fis, clone

BRACE2003217. Hs.285728 2

0.0001771 0.557 zinc finger protein 262 Hs.150390 ZNF262 1p32-p34 0.0001564 0.558 ADP-ribosylation factor 4-like Hs.183153 ARF4L 17q12-

q21 0.0001659 0.558 necdin homolog (mouse) Hs.50130 NDN 15q11.2-

q12 0.0001566 0.560 villin-like Hs.103665 VILL 3p21.3 2.49e-05 0.563 enhancer of zeste homolog 1 (Drosophila) Hs.194669 EZH1 17q21.1-

q21.3 0.0008561 0.565 glucan (1,4-alpha-), branching enzyme 1

(glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)

Hs.1691 GBE1 3p12.3

0.0001938 0.568 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

Hs.284202 XPNPEP1 10q25.3

1.3e-06 0.569 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2

Hs.114765 MLLT2 4q21

0.0003055 0.572 inositol polyphosphate-4-phosphatase, type II, 105kDa

Hs.153687 INPP4B 4q31.1

0.0001715 0.575 KIAA0563 gene product Hs.339808 KIAA0563 17q24.3 5.2e-06 0.584 MCM3 minichromosome maintenance

deficient 3 (S. cerevisiae) associated protein

Hs.168481 MCM3AP 21q22.3

3.83e-05 0.587 myotubular myopathy 1 Hs.75302 MTM1 Xq28 0.0004716 0.593 membrane-bound transcription factor

protease, site 1 Hs.75890 MBTPS1 16q24

0.0007184 0.595 hydroxysteroid (17-beta) dehydrogenase 2 Hs.155109 HSD17B2 16q24.1-q24.2

1.15e-05 0.596 A kinase (PRKA) anchor protein (yotiao) 9 Hs.58103 AKAP9 7q21-q22 5.37e-05 0.599 zinc finger protein 103 homolog (mouse) Hs.155968 ZFP103 2p11.2 0.0006073 0.599 KIAA0998 protein Hs.131525 KIAA0998 14q24.3 0.0002037 0.602 myc-induced nuclear antigen, 53 kDa Hs.23294 MINA53 3q12.1 0.0003112 0.602 NADPH oxidase activator 1 Hs.132883 NOXA1 0.0005219 0.608 eukaryotic translation initiation factor 3,

subunit 1 alpha, 35kDa Hs.173987 EIF3S1 15q15.1

5.03e-05 0.609 CDC16 cell division cycle 16 homolog (S. cerevisiae)

Hs.1592 CDC16 13q34

0.0001812 0.614 peroxisome biogenesis factor 10 Hs.247220 PEX10 1p36.32 0.0002332 0.615 bromodomain containing 8 Hs.5464 BRD8 5q31 0.000596 0.619 ADP-ribosyltransferase (NAD+; poly (ADP-

ribose) polymerase)-like 1 Hs.77225 ADPRTL1 13q11

0.0006213 0.621 carboxypeptidase D Hs.5057 CPD 17p11.1-q11.2

0.0003047 0.627 hypothetical protein BC014311 Hs.356358 LOC115548 5q13.1 0.0003236 0.630 bromodomain containing 8 Hs.5464 BRD8 5q31 0.0004333 0.630 adenylate cyclase 7 Hs.172199 ADCY7 16q12-

q13 0.0007737 0.631 hypothetical protein DKFZp564D172 Hs.25307 DKFZP564D172 5q14.3 0.0007329 0.632 cytochrome P450, family 2, subfamily B,

polypeptide 7 pseudogene Hs.330780 CYP2B7 19q13.2

0.000649 0.635 Alstrom syndrome 1 Hs.97393 ALMS1 2p13 0.0004968 0.644 kallikrein 2, prostatic Hs.181350 KLK2 19q13.41 0.0008581 0.644 retinal outer segment membrane protein 1 Hs.281564 ROM1 11q13 0.0001389 0.645 Incyte EST 0.0002475 0.661 nuclear receptor subfamily 1, group D, Hs.276916 NR1D1 17q11.2

member 1 0.0001351 0.669 glycosyltransferase AD-017 Hs.283737 AD-017 3p21.31 0.000917 0.674 hypothetical protein LOC125150 Hs.379903 LOC125150 17p11.2 0.000463 0.678 platelet-activating factor acetylhydrolase 2,

40kDa Hs.234392 PAFAH2 1p34.3

0.0006778 0.679 dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

0.0003677 0.685 SH3-domain binding protein 1 Hs.97858 SH3BP1 22q13.1 0.0008181 0.692 splicing factor, arginine/serine-rich 4 Hs.76122 SFRS4 1p35.2 0.0003138 0.748 zinc finger protein 161 homolog (mouse) Hs.156000 ZFP161 18pter-

p11.2 8.5e-06 0.783 WD40 and FYVE domain containing 2 Hs.16400 WDFY2 13q14.12 0.0005751 1.267 processing of precursors 1 Hs.170114 POP1 8q22.1 0.0006412 1.281 cyclin I Hs.79933 CCNI 4q21.21 0.0005564 1.353 splicing factor, arginine/serine-rich 3 Hs.388623 SFRS3 6p21 0.0003034 1.376 solute carrier family 6 (neurotransmitter

transporter, serotonin), member 4 Hs.553 SLC6A4 17q11.1-

q12 0.0007332 1.427 serine (or cysteine) proteinase inhibitor,

clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

Hs.159509 SERPINF2 17p13

0.0007919 1.469 general transcription factor IIIC, polypeptide 4, 90kDa

Hs.22302 GTF3C4 9q34.3

5.1e-05 1.470 hypothetical protein LOC220988 Hs.249247 LOC220988 2q31.2 0.000339 1.491 activator of basal transcription 1 Hs.109428 ABT1 6p21.33 0.000764 1.523 tumor necrosis factor receptor superfamily,

member 9 Hs.73895 TNFRSF9 1p36

0.00057 1.525 integrin, alpha 7 Hs.74369 ITGA7 12q13 0.0001638 1.531 integrin, beta 4 Hs.85266 ITGB4 17q11-

qter 5.85e-05 1.600 RAB21, member RAS oncogene family Hs.184627 RAB21 12q15 0.0009009 1.613 tripartite motif-containing 16 Hs.241305 TRIM16 17p11.2 0.0006462 1.713 interleukin enhancer binding factor 2,

45kDa Hs.75117 ILF2 1q21.3

0.0007185 1.718 zinc finger protein 230 Hs.193583 ZNF230 19q13.31 6.35e-05 1.734 T cell receptor delta locus Hs.2014 TRD@ 14q11.2 6.68e-05 1.774 syntaxin 6 Hs.157144 STX6 1q24.3 0.0002511 1.783 stathmin 1/oncoprotein 18 Hs.406269 STMN1 1p36.1-

p35 0.0008798 1.797 dual-specificity tyrosine-(Y)-phosphorylation

regulated kinase 3 Hs.38018 DYRK3 1q32

0.0002726 1.811 lymphocyte antigen 64 homolog, radioprotective 105kDa (mouse)

Hs.87205 LY64 5q12

3.6e-05 1.814 exostoses (multiple) 1 Hs.184161 EXT1 8q24.11-q24.13

0.0003265 1.835 E2F transcription factor 3 Hs.1189 E2F3 6p22 0.0001035 1.848 thymopoietin Hs.406660 TMPO 12q22 0.0002883 1.860 activator of S phase kinase Hs.152759 ASK 7q21.3 0.0005633 1.866 splicing factor, arginine/serine-rich 10

(transformer 2 homolog, Drosophila) Hs.30035 SFRS10 3q26.2-

q27 0.0004944 1.886 membrane-spanning 4-domains, subfamily

A, member 6A Hs.17914 MS4A6A 11q12.1

7.9e-06 1.889 syntaxin 6 Hs.157144 STX6 1q24.3 3.13e-05 1.893 TED protein Hs.87619 TED Xq13.1 0.0002484 1.900 troponin T2, cardiac Hs.296865 TNNT2 1q32 0.0008317 1.954 prefoldin 4 Hs.91161 PFDN4 20q13 3.06e-05 1.965 v-ral simian leukemia viral oncogene

homolog A (ras related) Hs.6906 RALA 7p22-p15

0.0003666 1.970 degenerative spermatocyte homolog, lipid desaturase (Drosophila)

Hs.185973 DEGS 1q42.12

0.0003457 2.049 CHK1 checkpoint homolog (S. pombe) Hs.20295 CHEK1 11q24-q24

0.000237 2.053 ERO1-like beta (S. cerevisiae) Hs.150763 ERO1LB 1q42.2-q43

0.0002466 2.089 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Hs.90280 ATIC 2q35

0.0004902 2.090 likely ortholog of mouse gene rich cluster, C8 gene

Hs.30114 GRCC8 12p13

2.28e-05 2.103 transmembrane 7 superfamily member 1 (upregulated in kidney)

Hs.15791 TM7SF1 1q42-q43

0.0005856 2.109 uridine monophosphate kinase Hs.95734 UMPK 1q23 0.0001729 2.147 cyclin B1 Hs.23960 CCNB1 5q12 8.49e-05 2.149 centromere protein F, 350/400ka (mitosin) Hs.77204 CENPF 1q32-q41 0.0002885 2.156 syndecan 2 (heparan sulfate proteoglycan

1, cell surface-associated, fibroglycan) Hs.1501 SDC2 8q22-q23

0.0005978 2.242 H2A histone family, member Z Hs.119192 H2AFZ 4q24 1.67e-05 2.274 discs, large homolog 7 (Drosophila) Hs.77695 DLG7 14q22.1 0.0004758 2.276 zinc finger protein 281 Hs.59757 ZNF281 1q32.1 0.0004636 2.317 matrix metalloproteinase 11 (stromelysin 3) Hs.155324 MMP11 22q11.23 0.0002697 2.488 fibromodulin Hs.230 FMOD 1q32

0.0001527 2.499 frizzled homolog 7 (Drosophila) Hs.173859 FZD7 2q33 0.000332 2.521 diacylglycerol O-acyltransferase homolog 2

(mouse) Hs.334305 DGAT2 11q13.3

0.0007263 2.553 degenerative spermatocyte homolog, lipid desaturase (Drosophila)

Hs.185973 DEGS 1q42.12

4.1e-06 2.681 kinesin family member 14 Hs.3104 KIF14 1pter-q31.3

1.44e-05 2.740 exonuclease 1 Hs.47504 EXO1 1q42-q43 0.0008026 2.741 phosphoribosylaminoimidazole

carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

Hs.117950 PAICS 4pter-q21

0.0003098 2.754 topoisomerase (DNA) II alpha 170kDa Hs.156346 TOP2A 17q21-q22

2.69e-05 2.931 claudin 1 Hs.7327 CLDN1 3q28-q29 0.0008088 2.951 Spi-B transcription factor (Spi-1/PU.1

related) Hs.192861 SPIB 19q13.3-

q13.4 0.000643 2.968 steroidogenic acute regulatory protein Hs.3132 STAR 8p11.2 0.0002634 3.072 phorbol-12-myristate-13-acetate-induced

protein 1 Hs.96 PMAIP1 18q21.31

0.0003994 3.103 claudin 1 Hs.7327 CLDN1 3q28-q29 5.47e-05 3.104 cyclin D2 Hs.75586 CCND2 12p13 0.0008514 3.147 CD83 antigen (activated B lymphocytes,

immunoglobulin superfamily) Hs.79197 CD83 6p23

0.0005441 3.753 MAD2 mitotic arrest deficient-like 1 (yeast) Hs.79078 MAD2L1 4q27

Supplemental Table 3 List of genes differentially expressed in metaplastic and displastic lesions (R) and carcinoma (T). Parametric

p-value Fold

difference of geometric

means (R vs T)

Gene symbol

p < 1e-07 0.031 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

IncytePD:2060355 Hs.73848 CEACAM6 19q13.2

3e-07 0.045 secretory leukocyte protease inhibitor (antileukoproteinase)

IncytePD:2510171 Hs.251754 SLPI 20q12

p < 1e-07 0.047 S100 calcium binding protein P IncytePD:2060823 Hs.2962 S100P 4p16 0.0001337 0.052 serine (or cysteine) proteinase inhibitor,

clade B (ovalbumin), member 3 IncytePD:2795874 Hs.227948 SERPINB3 18q21.3

0.0002589 0.077 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2

0.000152 0.088 keratin 4 IncytePD:1600453 Hs.3235 KRT4 12q12-q13

0.0002952 0.090 tetraspan 1 IncytePD:2989680 Hs.38972 TSPAN-1 1p33 9.3e-06 0.091 tumor-associated calcium signal

transducer 2 IncytePD:1600421 Hs.23582 TACSTD2 1p32-p31

0.0009022 0.094 uroplakin 1B IncytePD:2932992 Hs.271580 UPK1B 3q13.3-q21

1.5e-06 0.109 coagulation factor III (thromboplastin, tissue factor)

IncytePD:2061594 Hs.62192 F3 1p22-p21

0.0001048 0.117 ESTs, Weakly similar to CGHU7L collagen alpha 1(III) chain precursor - human [H.sapiens]

IncytePD:938641 Hs.355747 1

4.79e-05 0.121 mucin 1, transmembrane IncytePD:2957567 Hs.89603 MUC1 1q21 1.2e-06 0.135 likely ortholog of mouse tumor necrosis-

alpha-induced adipose-related protein IncytePD:429577 Hs.44208 FLJ23153 7q21.12

0.0003502 0.142 annexin A1 IncytePD:79576 Hs.78225 ANXA1 9q12-q21.2

2e-07 0.148 UDP glycosyltransferase 1 family, polypeptide A1

IncytePD:86450 Hs.278896 UGT1A1 2q37

5.54e-05 0.159 defensin, beta 1 IncytePD:2912830 Hs.32949 DEFB1 8p23.2-p23.1

0.0001838 0.160 retinoic acid induced 3 IncytePD:2060304 Hs.194691 RAI3 12p13-p12.3

0.0006128 0.172 interleukin 1 receptor antagonist IncytePD:519653 Hs.81134 IL1RN 2q14.2 0.0005417 0.179 polymeric immunoglobulin receptor IncytePD:1800114 Hs.205126 PIGR 1q31-q41 0.0006216 0.182 ATPase, Class V, type 10B IncytePD:2532486 Hs.109358 ATP10B 5q34 1.95e-05 0.189 B-factor, properdin IncytePD:167371 Hs.69771 BF 6p21.3 9.9e-06 0.211 sodium channel, nonvoltage-gated 1

alpha IncytePD:1453049 Hs.446415 SCNN1A 12p13

2.11e-05 0.213 Homo sapiens, clone IMAGE:4471726, mRNA

IncytePD:899118 Hs.288660 12

0.0002516 0.217 ESTs IncytePD:931235 Hs.445586 19 7.44e-05 0.218 kallikrein 10 IncytePD:2851003 Hs.69423 KLK10 19q13.3-

q13.4 7.61e-05 0.220 serine (or cysteine) proteinase inhibitor,

clade B (ovalbumin), member 1 IncytePD:2595929 Hs.183583 SERPINB1 6p25

0.0004069 0.22 zinc finger protein 185 (LIM domain) IncytePD:2510927 Hs.16622 ZNF185 Xq28 0.0001657 0.232 kallikrein 6 (neurosin, zyme) IncytePD:1480159 Hs.79361 KLK6 19q13.3 0.0009484 0.232 thyroid hormone receptor interactor 4 IncytePD:1970421 Hs.116784 TRIP4 15q22.1 0.0006364 0.237 leukocyte immunoglobulin-like receptor,

subfamily B (with TM and ITIM domains), member 5

IncytePD:3508771 Hs.77062 LILRB5 19q13.4

8.02e-05 0.242 monoamine oxidase A IncytePD:1510714 Hs.183109 MAOA Xp11.4-p11.3

0.0005976 0.251 kallikrein 11 IncytePD:2668780 Hs.57771 KLK11 19q13.3-q13.4

6.11e-05 0.252 LIM domain only 7 IncytePD:1832584 Hs.5978 LMO7 13q21.33 0.0007485 0.252 selenoprotein P, plasma, 1 IncytePD:2959255 Hs.275775 SEPP1 5q31 5.6e-06 0.256 pre-B-cell colony-enhancing factor IncytePD:1641590 Hs.239138 PBEF 7q22.1 0.0001669 0.262 EphA2 IncytePD:1958394 Hs.171596 EPHA2 1p36 8.4e-06 0.267 epidermal growth factor receptor

pathway substrate 8-related protein 1 IncytePD:1395088 Hs.28907 EPS8R1 19q13.42

0.0004759 0.272 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3

IncytePD:1758055 Hs.278611 GALNT3 2q24-q31

(GalNAc-T3) 3.92e-05 0.273 anterior gradient 2 homolog (Xenepus

laevis) IncytePD:1998428 Hs.413945 AGR2 7p21.3

4.66e-05 0.287 Incyte EST IncytePD:1260330 0.0005075 0.288 cellular retinoic acid binding protein 2 IncytePD:4083362 Hs.183650 CRABP2 1q21.3 0.0006567 0.292 epiregulin IncytePD:443631 Hs.115263 EREG 4q21.1 5.02e-05 0.293 monoglyceride lipase IncytePD:2174920 Hs.6721 MGLL 3q21.3 9.86e-05 0.295 Kruppel-like factor 4 (gut) IncytePD:1962235 Hs.356370 KLF4 9q31 9.37e-05 0.301 spermidine/spermine N1-

acetyltransferase IncytePD:63038 Hs.28491 SAT Xp22.1

0.0002604 0.303 sushi-repeat protein IncytePD:3598293 Hs.126782 SRPUL Xq21.33-q23

0.0002916 0.304 glutathione peroxidase 2 (gastrointestinal)

IncytePD:1633118 Hs.2704 GPX2 14q24.1

0.0006359 0.305 annexin A2 IncytePD:5077219 Hs.217493 ANXA2 15q21-q22

0.0001596 0.309 prostate stem cell antigen IncytePD:1900949 Hs.423634 PSCA 8q24.2 0.0003083 0.328 claudin 7 IncytePD:2060261 Hs.278562 CLDN7 17p13 0.0001827 0.343 heparan sulfate (glucosamine) 3-O-

sulfotransferase 1 IncytePD:513943 Hs.40968 HS3ST1 4p16

1.15e-05 0.345 LIM domain only 2 (rhombotin-like 1) IncytePD:1383888 Hs.184585 LMO2 11p13 0.0003592 0.349 transforming growth factor, alpha IncytePD:3125996 Hs.170009 TGFA 2p13 8.2e-06 0.355 Rho GTPase-activating protein IncytePD:2283906 Hs.111138 RICS 11q24-

q25 0.0003702 0.355 protein tyrosine phosphatase, receptor-

type, Z polypeptide 1 IncytePD:1615557 Hs.78867 PTPRZ1 7q31.3

0.0004568 0.360 statherin IncytePD:1825492 Hs.37048 STATH 4q11-q13 1e-07 0.361 Homo sapiens cDNA FLJ13510 fis,

clone PLACE1005146. IncytePD:64451 Hs.37896 2

0.0001212 0.367 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

IncytePD:1988412 Hs.166096 ELF3 1q32.2

2.4e-06 0.37 hypothetical protein FLJ22418 IncytePD:2816379 Hs.36563 FLJ22418 1p11.1 0.0007074 0.374 protease, serine, 3 (mesotrypsin) IncytePD:2792982 Hs.58247 PRSS3 9p11.2 0.0004099 0.376 fucosyltransferase 3 (galactoside 3(4)-

L-fucosyltransferase, Lewis blood group included)

IncytePD:2354446 Hs.169238 FUT3 19p13.3

5.8e-05 0.377 keratin 7 IncytePD:1649959 Hs.23881 KRT7 12q12-q13

5.22e-05 0.379 keratin 7 IncytePD:1962141 Hs.23881 KRT7 12q12-q13

3.04e-05 0.38 KIAA0790 protein IncytePD:1722691 Hs.12002 KIAA0790 6q24.3 4.32e-05 0.38 hypothetical protein MGC29643 IncytePD:2016229 Hs.372651 MGC29643 2q21.1 6.09e-05 0.387 calpastatin IncytePD:1453748 Hs.359682 CAST 5q15-q21 0.0001728 0.39 hypothetical protein MGC16491 IncytePD:3408084 Hs.59771 MGC16491 1p35.3 5.23e-05 0.393 nuclear receptor coactivator 6

interacting protein IncytePD:2239295 Hs.179909 NCOA6IP 8q11

9.28e-05 0.396 transmembrane protease, serine 2 IncytePD:991163 Hs.318545 TMPRSS2 21q22.3 0.0001896 0.399 dihydropyrimidine dehydrogenase IncytePD:1485479 Hs.1602 DPYD 1p22 0.0004989 0.403 myosin ID IncytePD:1556011 Hs.39871 MYO1D 17q11-

q12 0.0007907 0.411 transmembrane 4 superfamily member

6 IncytePD:1701627 Hs.121068 TM4SF6 Xq22

0.0002794 0.417 coagulation factor II (thrombin) receptor-like 1

IncytePD:1801553 Hs.154299 F2RL1 5q13

0.0002119 0.419 Homo sapiens cDNA: FLJ20869 fis, clone ADKA02377.

IncytePD:3143579 Hs.194101 12

0.0006584 0.43 hypothetical protein from clone 643 IncytePD:1451876 Hs.206501 LOC57228 12q13.12 0.0009365 0.437 epithelial membrane protein 1 IncytePD:1624024 Hs.79368 EMP1 12p12.3 0.0007938 0.442 CD59 antigen p18-20 (antigen identified

by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)

IncytePD:2060621 Hs.278573 CD59 11p13

0.0005395 0.443 galactose-4-epimerase, UDP- IncytePD:1807294 Hs.76057 GALE 1p36-p35 p < 1e-07 0.445 protein tyrosine phosphatase, receptor

type, U IncytePD:2941607 Hs.19718 PTPRU 1p35.3-

p35.1 0.0002042 0.445 solute carrier family 1

(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

3.14e-05 0.453 FK506 binding protein 1B, 12.6 kDa IncytePD:1288118 Hs.77643 FKBP1B 2p24.1 0.0005611 0.457 Ste20-related serine/threonine kinase IncytePD:1968259 Hs.105751 SLK 10q24.32 4.22e-05 0.458 PTK6 protein tyrosine kinase 6 IncytePD:3255437 Hs.51133 PTK6 20q13.3 0.0008648 0.458 KIAA0089 protein IncytePD:1803418 Hs.82432 KIAA0089 3p22.3 0.000323 0.459 PlSC domain containing hypothetical

protein IncytePD:1889837 Hs.352614 LOC254531 15q13.2

0.0005902 0.461 ADP-ribosylation factor 4-like IncytePD:2852403 Hs.183153 ARF4L 17q12-q21

0.0004429 0.464 occludin IncytePD:3980393 Hs.171952 OCLN 5q13.1 0.0003935 0.468 transglutaminase 1 (K polypeptide

epidermal type I, protein-glutamine-gamma-glutamyltransferase)

IncytePD:459817 Hs.22 TGM1 14q11.2

0.0006267 0.469 interleukin 1 receptor accessory protein IncytePD:1431707 Hs.173880 IL1RAP 3q28 4.2e-06 0.478 inositol polyphosphate-4-phosphatase,

type II, 105kDa IncytePD:3032739 Hs.153687 INPP4B 4q31.1

0.0005236 0.479 apolipoprotein D IncytePD:3948420 Hs.75736 APOD 3q26.2-qter

0.0001591 0.484 formyltetrahydrofolate dehydrogenase IncytePD:2104145 Hs.9520 FTHFD 3q21.2 0.0005966 0.486 diaphorase (NADH/NADPH)

(cytochrome b-5 reductase) IncytePD:2637222

0.0004412 0.487 cytochrome P450, family 24, subfamily A, polypeptide 1

IncytePD:3118873 Hs.89663 CYP24A1 20q13

0.0005154 0.488 nei endonuclease VIII-like 1 (E. coli) IncytePD:1926409 Hs.28355 NEIL1 15q22.33 0.0002433 0.489 EphB3 IncytePD:1227385 Hs.2913 EPHB3 3q21-qter 0.000889 0.490 histamine receptor H1 IncytePD:1210839 Hs.1570 HRH1 3p25 1e-06 0.492 ESTs IncytePD:2136337 Hs.110044 9 3.8e-06 0.505 UDP-N-acetyl-alpha-D-

IncytePD:2815133 Hs.271923 GALNT4 12q21.3-q22

0.0006595 0.506 histone 1, H1c IncytePD:1574890 Hs.7644 HIST1H1C 6p21.3 0.0009171 0.51 enthoprotin IncytePD:1561222 Hs.132853 ENTH 5q23.1-

q33.3 0.0005141 0.513 guanine nucleotide binding protein (G

protein), gamma 4 IncytePD:1756834 Hs.32976 GNG4 1q42.3

0.0007522 0.527 tumor necrosis factor receptor superfamily, member 21

IncytePD:1991290 Hs.159651 TNFRSF21 6p21.1-12.2

0.000952 0.528 Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse)

IncytePD:1662216 Hs.380923 MEIS3 17p11.2

0.0007614 0.529 hairy and enhancer of split 1, (Drosophila)

IncytePD:2058935 Hs.250666 HES1 3q28-q29

5.36e-05 0.536 tripartite motif-containing 16 IncytePD:1996011 Hs.241305 TRIM16 17p11.2 6.51e-05 0.537 Homo sapiens DNA from chromosome

19, cosmid F21856 IncytePD:3615515

3.06e-05 0.547 hypothetical protein BC010682 IncytePD:1493357 Hs.4896 LOC90550 10q22.2 0.0007885 0.572 sortilin 1 IncytePD:2706090 0.0008931 0.582 peroxisome proliferative activated

receptor, delta IncytePD:2640712 Hs.106415 PPARD 6p21.2-

p21.1 0.0001597 0.584 5'-nucleotidase, cytosolic II IncytePD:2474690 Hs.138593 NT5C2 10q24.32 6.9e-06 0.599 Fanconi anemia, complementation

group A IncytePD:1647354

0.0008396 0.600 ESTs IncytePD:1984918 Hs.165795 14 0.0006036 0.603 dual adaptor of phosphotyrosine and 3-

phosphoinositides IncytePD:1304879 Hs.62643 DAPP1 4q25-q27

0.0006974 0.607 period homolog 3 (Drosophila) IncytePD:2289901 Hs.12592 PER3 1p36.22 6.21e-05 0.609 hypothetical protein FLJ32029 IncytePD:2929840 Hs.26612 FLJ32029 11q13.3 0.000887 0.616 ESTs IncytePD:1888036 Hs.427773 2 8.05e-05 0.628 hypothetical protein FLJ22004 IncytePD:2768580 Hs.108812 FLJ22004 2q13 0.000367 0.643 KIAA1295 protein IncytePD:1208611 Hs.26204 KIAA1295 5q35.2 0.0007872 0.661 retinoic acid receptor, beta IncytePD:2148583 Hs.171495 RARB 3p24 0.0003683 0.672 hypothetical protein FLJ11560 IncytePD:1990361 Hs.301696 FLJ11560 9p13.1 0.0001513 0.679 DKFZP434C212 protein IncytePD:1282176 Hs.172069 DKFZP434C212 9q34.11 0.0005234 1.243 chromosome 14 open reading frame

117 IncytePD:2652746 Hs.103189 C14orf117 14q24.1

0.0002028 1.322 zinc finger protein 161 homolog (mouse)

IncytePD:2487368 Hs.156000 ZFP161 18pter-p11.2

0.0002129 1.328 phosphatidylinositol glycan, class F IncytePD:1557568 Hs.426142 PIGF 2p21-p16 0.0006941 1.378 Homo sapiens, clone IMAGE:4152387,

mRNA IncytePD:2070637 Hs.46791 9

0.0005802 1.385 hypothetical protein LOC150819 IncytePD:2250987 Hs.84063 LOC150819 2q12.3 2.73e-05 1.405 Splicing factor, arginine/serine-rich,

46kD IncytePD:2511735 Hs.155160 SRP46 11q22

4.56e-05 1.425 tumor necrosis factor receptor superfamily, member 9

IncytePD:191843 Hs.73895 TNFRSF9 1p36

0.0006411 1.445 KIAA1340 protein IncytePD:2917963 Hs.51743 KIAA1340 12p11.23 0.0009423 1.471 KIAA0117 protein IncytePD:1238619 0.0002355 1.476 M-phase phosphoprotein 9 IncytePD:2508608 Hs.351230 MPHOSPH9 12q24.31 0.0002067 1.479 pogo transposable element with ZNF

domain IncytePD:1877933 Hs.107088 POGZ 1q21.2

0.0001549 1.502 sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)

IncytePD:471870 Hs.31176 SIRT1 10q22.1

0.0005706 1.506 embryonic ectoderm development IncytePD:2914968 Hs.151461 EED 11q14.2-q22.3

0.0001167 1.508 zinc finger protein with interaction domain

IncytePD:3728922 Hs.3053 ZID 9q34.11

0.0002195 1.528 D15F37 (pseudogene) IncytePD:2739109 Hs.426451 MN7 15q11-q13

0.0005221 1.545 hypothetical protein MGC9084 IncytePD:960406 Hs.33922 MGC9084 1q23.2 0.0009827 1.551 zinc finger protein 265 IncytePD:1845253 Hs.194718 ZNF265 1p31 0.0007871 1.554 Homo sapiens clone HQ0290 IncytePD:639847 Hs.446574 1 0.0006602 1.557 ubiquitin specific protease 14 (tRNA-

guanine transglycosylase) IncytePD:1707220 Hs.75981 USP14 18p11.32

0.0005359 1.573 chromosome 21 open reading frame 66 IncytePD:1358710 Hs.283771 C21orf66 21q21.3 0.0009143 1.579 Homo sapiens cDNA FLJ14232 fis,

clone NT2RP4000035. IncytePD:2243954 Hs.101810 6

0.000893 1.608 kinetochore associated 1 IncytePD:789903 Hs.333355 KNTC1 12q24.31 0.0003913 1.614 Bardet-Biedl syndrome 2 IncytePD:1723772 Hs.332633 BBS2 16q21 4.71e-05 1.618 nucleoporin-like protein 1 IncytePD:1922694 Hs.168352 NLP_1 7p15 4.26e-05 1.625 centromere protein A, 17kDa IncytePD:2444942 Hs.1594 CENPA 2p24-p21 0.0008911 1.628 splicing factor, arginine/serine-rich 10

(transformer 2 homolog, Drosophila) IncytePD:2457759 Hs.30035 SFRS10 3q26.2-

q27 0.0002741 1.656 heterogeneous nuclear

ribonucleoprotein C (C1/C2) IncytePD:2458656 Hs.418901 HNRPC 14q11.1

0.0006728 1.667 sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila

IncytePD:2612729 Hs.128759 SARM 17

3.79e-05 1.675 ESTs, Weakly similar to hypothetical protein FLJ20489 [Homo sapiens] [H.sapiens]

IncytePD:2285350 Hs.99216 15

0.0003634 1.675 polymerase (DNA directed), alpha IncytePD:1719446 Hs.267289 POLA Xp22.1-p21.3

3.11e-05 1.684 high mobility group nucleosomal binding domain 4

IncytePD:1748670 Hs.236774 HMGN4 6p21.3

0.000571 1.694 mannosidase, beta A, lysosomal IncytePD:1805840 Hs.115945 MANBA 4q22-q25 0.0005927 1.699 regulator of G-protein signalling 16 IncytePD:1890243 Hs.183601 RGS16 1q25-q31 0.0001148 1.704 hypothetical protein FLJ21016 IncytePD:1447393 Hs.289069 FLJ21016 1q42.12 6.3e-06 1.712 RNA binding motif protein 15 IncytePD:1379395 Hs.46670 RBM15 1p13 0.0004109 1.747 TED protein IncytePD:2409533 Hs.87619 TED Xq13.1 0.0007374 1.764 heterogeneous nuclear

ribonucleoprotein A1 IncytePD:1236655 Hs.376844 HNRPA1 12q13.1

8.72e-05 1.785 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

IncytePD:1994721 Hs.285013 ANP32A 15q22.3-q23

0.0003067 1.798 ESTs, Weakly similar to hypothetical protein FLJ22184 [Homo sapiens] [H.sapiens]

IncytePD:1451756 Hs.23272 6

0.0001401 1.812 thymopoietin IncytePD:2289176 Hs.406660 TMPO 12q22 0.0003649 1.812 5-aminoimidazole-4-carboxamide

ribonucleotide formyltransferase/IMP cyclohydrolase

IncytePD:2056149 Hs.90280 ATIC 2q35

7.51e-05 1.826 lamin B receptor IncytePD:1803808 Hs.152931 LBR 1q42.1 0.0001458 1.948 lamin B receptor IncytePD:564104 Hs.152931 LBR 1q42.1 0.0005024 2.179 vascular cell adhesion molecule 1 IncytePD:1642361 Hs.109225 VCAM1 1p32-p31 0.0002484 2.25 TBC1 domain family, member 4 IncytePD:924189 Hs.173802 TBC1D4 13q21.33 6.3e-06 2.263 lymphocyte adaptor protein IncytePD:1959371 Hs.13131 LNK 12q24 0.000283 2.317 baculoviral IAP repeat-containing 3 IncytePD:1603857 Hs.127799 BIRC3 11q22 2.6e-06 2.340 syndecan 2 (heparan sulfate

proteoglycan 1, cell surface-associated, fibroglycan)

IncytePD:1782172 Hs.1501 SDC2 8q22-q23

Supplemental Table 4 List of genes differentially expressed in normal nasopharyngeal epithelium (N) and metaplastic and displastic epithelium (R). Parametric

p-value Fold

difference of geometric

means (N vs R)

Gene symbol

5.46e-05 0.062 prominin-like 1 (mouse) IncytePD:2070568 Hs.112360 PROML1 4p15.33 2.87e-05 0.085 carboxylesterase 1 (monocyte/macrophage serine

esterase 1) IncytePD:1813269 Hs.76688 CES1 16q13-

q22.1 0.0006787 0.096 lactotransferrin IncytePD:1861911 Hs.105938 LTF 3q21-q23 5.45e-05 0.100 serum amyloid A4, constitutive IncytePD:86390 Hs.1955 SAA4 11p15.1-

p14 0.0003482 0.103 B-cell CLL/lymphoma 3 IncytePD:1867294 Hs.31210 BCL3 19q13.1-

q13.2 2.55e-05 0.109 selenium binding protein 1 IncytePD:2591494 Hs.334841 SELENBP1 1q21-q22 1.23e-05 0.131 melanoma inhibitory activity IncytePD:1911332 Hs.279651 MIA 19q13.32-

q13.33 2e-07 0.137 amylase, alpha 2B; pancreatic IncytePD:254081 Hs.335493 AMY2B 1p21 4.32e-05 0.149 complement component 4A IncytePD:1996090 Hs.170250 C4A 6p21.3 1.49e-05 0.164 phospholipase A2, group IB (pancreas) IncytePD:2383830 Hs.992 PLA2G1B 12q23-

q24.1 1.2e-06 0.166 benzodiazapine receptor (peripheral) associated protein 1 IncytePD:1865225 Hs.112499 BZRAP1 17q22-q23 0.0007326 0.173 ESTs, Weakly similar to neuronal thread protein [Homo

sapiens] [H.sapiens] IncytePD:2714867 Hs.436950 11

0.0004825 0.188 major histocompatibility complex, class II, DR beta 5 IncytePD:2105963 Hs.352392 HLA-DRB5 6p21.3 0.0002959 0.189 four and a half LIM domains 1 IncytePD:224996 Hs.239069 FHL1 Xq26 0.0002017 0.194 retinoic acid receptor responder (tazarotene induced) 1 IncytePD:1982324 Hs.82547 RARRES1 3q25.32 0.0008317 0.198 Incyte EST IncytePD:1507769 0.0001521 0.216 complement component 3 IncytePD:1513989 Hs.284394 C3 19p13.3-

p13.2 3.3e-06 0.217 polycystic kidney disease 1 (autosomal dominant) IncytePD:1887011 Hs.75813 PKD1 16p13.3 0.0002169 0.221 KIAA0675 gene product IncytePD:1794725 Hs.165662 KIAA0675 3q13.12 8.4e-06 0.225 major histocompatibility complex, class II, DM alpha IncytePD:2059338 Hs.77522 HLA-DMA 6p21.3 0.0007868 0.226 CD8 antigen, beta polypeptide 1 (p37) IncytePD:2656104 Hs.2299 CD8B1 2p12 1.5e-06 0.236 ribonuclease, RNase A family, 4 IncytePD:1858905 Hs.283749 RNASE4 14q11.1 2.69e-05 0.239 neuroblastoma, suppression of tumorigenicity 1 IncytePD:1816413 Hs.76307 NBL1 1p36.3-

p36.2 0.000705 0.247 SPARC-like 1 (mast9, hevin) IncytePD:3721788 Hs.75445 SPARCL1 4q22.1 1.14e-05 0.251 fibulin 5 IncytePD:2060177 Hs.11494 FBLN5 14q32.1 0.0001223 0.252 Homo sapiens cDNA FLJ20115 fis, clone COL05594 IncytePD:2716261 0.0001101 0.261 transforming growth factor, beta receptor III (betaglycan,

300kDa) IncytePD:1443766 Hs.342874 TGFBR3 1p33-p32

6.41e-05 0.267 ectonucleoside triphosphate diphosphohydrolase 6 (putative function)

IncytePD:1511486 Hs.12330 ENTPD6 20p11.2-p11.22

2.83e-05 0.274 Homo sapiens colon cancer antigen NY-CO-45 mRNA, partial cds

IncytePD:275494 Hs.160881 6

5e-07 0.275 ATPase, Class II, type 9A IncytePD:1942046 Hs.406434 ATP9A 20q13.11-q13.2

0.0009855 0.284 hepatocellular carcinoma-associated antigen 112 IncytePD:409677 Hs.12126 HCA112 7q36.1 4e-07 0.285 iduronate 2-sulfatase (Hunter syndrome) IncytePD:549290 Hs.172458 IDS Xq28 0.0005432 0.285 ESTs IncytePD:3144431 Hs.56220 1 7e-06 0.287 Fc fragment of IgG, receptor, transporter, alpha IncytePD:1871295 Hs.111903 FCGRT 19q13.3 0.0001881 0.288 cysteine-rich protein 2 IncytePD:2672064 Hs.70327 CRIP2 14q32.3 0.0002332 0.288 ADP-ribosyltransferase 3 IncytePD:2011270 Hs.24976 ART3 4p15.1-

p14 0.0003998 0.291 Duffy blood group IncytePD:1987335 Hs.183 FY 1q21-q22 4e-06 0.295 calmin (calponin-like, transmembrane) IncytePD:1464613 Hs.406099 CLMN 14q32.2 1.54e-05 0.295 hypothetical protein LOC283445 IncytePD:1968776 Hs.234898 LOC283445 12q24.12 5.08e-05 0.295 Homo sapiens clone 24790 mRNA sequence IncytePD:866608 Hs.13431 12 2.61e-05 0.298 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein

1 (chondrocyte-derived) IncytePD:1966067 Hs.183738 FARP1 13q32.2

0.0001598 0.298 serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

IncytePD:2989991 Hs.173594 SERPINF1 17p13.1

5e-07 0.301 KIAA0590 gene product IncytePD:1996021 Hs.111862 KIAA0590 16p13.3 0.0001196 0.302 nischarin IncytePD:1809315 Hs.26285 NISCH 3p21.1 5.45e-05 0.305 acetyl-Coenzyme A synthetase 2 (AMP forming)-like IncytePD:2132717 Hs.7218 ACAS2L 20p11.23-

p11.21 2.71e-05 0.309 zinc finger protein 204 IncytePD:1454640 Hs.8198 ZNF204 6p21.3 0.0009317 0.31 hypothetical protein MGC10500 IncytePD:1923722 Hs.271599 MGC10500 16p11.2 6.99e-05 0.312 nuclear receptor subfamily 3, group C, member 2 IncytePD:1678071 Hs.1790 NR3C2 4q31.1 0.0008365 0.316 mucin 5, subtype B, tracheobronchial IncytePD:1737280 Hs.102482 MUC5B 11p15 0.000238 0.317 sodium channel, nonvoltage-gated 1 alpha IncytePD:1453049 Hs.446415 SCNN1A 12p13 9.82e-05 0.320 Probe hTg737 (polycystic kidney disease, autosomal

recessive) IncytePD:1663493 Hs.2291 TG737 13q12.1

3e-06 0.322 Homo sapiens cDNA FLJ10158 fis, clone HEMBA1003463.

IncytePD:3144018 Hs.104627 3

1.35e-05 0.323 nei like 2 (E. coli) IncytePD:2025662 Hs.293818 NEIL2 8 8.68e-05 0.323 hypothetical protein FLJ13868 IncytePD:1857438 Hs.9003 FLJ13868 16p11.2 2.2e-05 0.325 SWI/SNF related, matrix associated, actin dependent

regulator of chromatin, subfamily d, member 3 IncytePD:1888940 Hs.71622 SMARCD3 7q35-q36

0.0007464 0.327 echinoderm microtubule associated protein like 1 IncytePD:1482116 Hs.12451 EML1 14q32 3.54e-05 0.329 CD99 antigen IncytePD:3031028 Hs.433387 CD99 Xp22.32 3.6e-06 0.330 galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio

syndrome, mucopolysaccharidosis type IVA) IncytePD:2903239 Hs.159479 GALNS 16q24.3

4.6e-06 0.330 truncated calcium binding protein IncytePD:1943110 Hs.351621 LOC51149 5q35.3 0.0008471 0.334 enolase 2, (gamma, neuronal) IncytePD:1672630 Hs.146580 ENO2 12p13 0.0005189 0.337 complement component 1, q subcomponent, beta

polypeptide IncytePD:2102756 Hs.8986 C1QB 1p36.3-

p34.1 0.0005773 0.338 T cell receptor gamma variable 9 IncytePD:1857652 Hs.112259 TRGV9 7p15 5.93e-05 0.339 hypothetical protein FLJ20154 IncytePD:2132451 Hs.10346 FLJ20154 10q24.32 5e-07 0.341 NIMA (never in mitosis gene a)- related kinase 9 IncytePD:1661837 Hs.7200 NEK9 14q24.2 0.0006756 0.341 PTH-responsive osteosarcoma B1 protein IncytePD:15650 Hs.79340 B1 7p14 8.9e-06 0.342 calcium channel, voltage-dependent, beta 3 subunit IncytePD:2057662 Hs.250712 CACNB3 12q13 0.0005288 0.342 axin 2 (conductin, axil) IncytePD:2359588 Hs.127337 AXIN2 17q23-q24 3.26e-05 0.343 ectonucleoside triphosphate diphosphohydrolase 1 IncytePD:1672749 Hs.205353 ENTPD1 10q24 0.0001738 0.345 ubiquitin specific protease 11 IncytePD:1805270 Hs.171501 USP11 Xp11.23 0.0001125 0.347 cyclin-dependent kinase 3 IncytePD:2259295 Hs.100009 CDK3 17q22-qter 8.1e-06 0.348 HRAS-like suppressor 3 IncytePD:1969263 Hs.37189 HRASLS3 11q12.3 0.0001534 0.349 galactosylceramidase (Krabbe disease) IncytePD:1430428 Hs.273 GALC 14q31 0.0004065 0.350 transforming growth factor beta-stimulated protein TSC-22 IncytePD:197908 Hs.114360 TSC22 13q14 0.0005233 0.350 Homo sapiens, clone IMAGE:4766144, mRNA IncytePD:1666815 Hs.72080 21 8.51e-05 0.351 DKFZP586A0522 protein IncytePD:1965049 Hs.288771 DKFZP586A052 12q13.12 0.0001863 0.352 SAC2 suppressor of actin mutations 2-like (yeast) IncytePD:1902608 Hs.169407 SACM2L 6p21.3 6.07e-05 0.353 ESTs IncytePD:2359527 Hs.279482 2 2.75e-05 0.354 Homo sapiens cDNA FLJ10158 fis, clone

HEMBA1003463. IncytePD:1967531 Hs.104627 3

3.76e-05 0.355 nuclear RNA export factor 1 IncytePD:1890753 Hs.323502 NXF1 11q12-q13 0.0002937 0.355 hypothetical protein RP4-622L5 IncytePD:3223070 Hs.272299 RP4-622L5 1p36.11-

p34.2 0.000137 0.359 AXL receptor tyrosine kinase IncytePD:2058242 Hs.83341 AXL 19q13.1 3.1e-06 0.363 TBP-interacting protein IncytePD:1842689 Hs.154740 TIP120B 3p25.1 0.0001377 0.364 Arg/Abl-interacting protein ArgBP2 IncytePD:1495766 Hs.379795 ARGBP2 4q35.1 4.3e-05 0.365 rTS beta protein IncytePD:1808980 Hs.180433 HSRTSBETA 18p11.32 9.07e-05 0.366 SET binding protein 1 IncytePD:2903158 Hs.151717 SETBP1 18q21.1 0.0007286 0.366 serine (or cysteine) proteinase inhibitor, clade B

(ovalbumin), member 6 IncytePD:1904994 Hs.41072 SERPINB6 6p25

7.14e-05 0.368 delta sleep inducing peptide, immunoreactor IncytePD:2307314 Hs.75450 DSIPI Xq22.3 0.0007052 0.368 protease, serine, 11 (IGF binding) IncytePD:1958902 Hs.75111 PRSS11 10q26.3 0.0001494 0.371 Homo sapiens, Similar to RIKEN cDNA 1110030M18

gene, clone IMAGE:4810207, mRNA IncytePD:3473302 Hs.436170 14

0.0007285 0.371 forkhead box G1A IncytePD:94367 Hs.169277 FOXG1A 14q13 1e-04 0.372 KIAA1538 protein IncytePD:1381261 Hs.35096 KIAA1538 17p13.1 5.53e-05 0.373 chemokine (C-X3-C motif) ligand 1 IncytePD:1728607 Hs.80420 CX3CL1 16q13 0.0001338 0.373 cytochrome P450, family 2, subfamily J, polypeptide 2 IncytePD:1597231 Hs.152096 CYP2J2 1p31.3-

p31.2 6.31e-05 0.374 nei endonuclease VIII-like 1 (E. coli) IncytePD:1926409 Hs.28355 NEIL1 15q22.33 0.0003121 0.375 KIAA0445 gene product IncytePD:2119925 Hs.301065 KIAA0445 1pter-

p36.11 6.08e-05 0.376 ESTs IncytePD:2818878 Hs.32135 20 0.0009504 0.378 armadillo repeat gene deletes in velocardiofacial syndrome IncytePD:928436 Hs.171900 ARVCF 22q11.21 4.6e-06 0.380 acylphosphatase 1, erythrocyte (common) type IncytePD:1995749 Hs.18573 ACYP1 14q24.3 1.66e-05 0.384 oxysterol binding protein-like 5 IncytePD:2021590 Hs.112034 OSBPL5 11p15.4 5.53e-05 0.386 integrin-linked kinase IncytePD:543915 Hs.6196 ILK 11p15.5-

p15.4 0.0001314 0.386 chemokine (C-C motif) receptor 2 IncytePD:2446447 Hs.395 CCR2 3p21 3e-07 0.389 KIAA1958 protein IncytePD:4109001 Hs.350795 KIAA1958 9q32 6.02e-05 0.389 zinc finger protein 3 (A8-51) IncytePD:997067 Hs.155470 ZNF3 7q22.1 0.0001258 0.389 interferon-stimulated transcription factor 3, gamma 48kDa IncytePD:1942550 Hs.1706 ISGF3G 14q11.2 0.0008056 0.391 AT-hook transcription factor AKNA IncytePD:1250542 Hs.159578 AKNA 9q32 6.38e-05 0.393 ESTs IncytePD:2917169 Hs.42294 19 0.0004716 0.393 sulfotransferase family, cytosolic, 1A, phenol-preferring,

member 3 IncytePD:1694591 Hs.274614 SULT1A3 16p11.2

0.0002225 0.394 Incyte EST IncytePD:2720976 0.0007596 0.394 myosin, heavy polypeptide 10, non-muscle IncytePD:1923476 Hs.296842 MYH10 17p13 0.0009937 0.396 hypothetical protein FLJ13942 IncytePD:2041712 Hs.20537 FLJ13942 6q22.31 0.0002649 0.397 solute carrier family 23 (nucleobase transporters), member

1 IncytePD:1259230 Hs.82042 SLC23A1 20p13

0.0006627 0.397 Bernardinelli-Seip congenital lipodystrophy 2 (seipin) IncytePD:553371 Hs.293981 BSCL2 11q12-q13.5

0.000319 0.399 hypothetical protein FLJ10300 IncytePD:3881016 Hs.42233 FLJ10300 7q36.3 0.0004549 0.400 splicing factor 4 IncytePD:1639267 Hs.15075 SF4 19p13.11 4.94e-05 0.401 methyltransferase like 3 IncytePD:1903759 Hs.268149 METTL3 14q11.1 0.0004407 0.401 hypothetical protein FLJ21347 IncytePD:1614502 Hs.103147 FLJ21347 17q21.33 0.0006363 0.401 macrophage stimulating, pseudogene 9 IncytePD:1379063 Hs.278657 MSTP9 1p36.13 0.0008973 0.401 ESTs IncytePD:2556393 Hs.381113 4 5e-07 0.402 Homo sapiens cDNA FLJ11606 fis, clone

HEMBA1003942. IncytePD:1730917 Hs.283643 1

0.000147 0.403 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa IncytePD:2056955 Hs.7744 NDUFV1 11q13 0.0003136 0.403 hypothetical protein FLJ20345 IncytePD:1495247 Hs.20558 FLJ20345 17q23.2 0.0004417 0.403 Homo sapiens, clone IMAGE:5587702, mRNA IncytePD:1964852 Hs.427683 10 1.4e-05 0.405 KIAA0195 gene product IncytePD:3203789 Hs.301132 KIAA0195 17q25.2 0.0005215 0.405 ATP-binding cassette, sub-family F (GCN20), member 2 IncytePD:2185537 Hs.153612 ABCF2 7q36 0.0007582 0.406 histidine decarboxylase IncytePD:1998060 Hs.1481 HDC 15q21-q22 6.58e-05 0.407 REMOVED_FROM_DATABASE IncytePD:91009 0.0001652 0.407 phosphatidylinositol glycan, class Q IncytePD:1511484 Hs.18079 PIGQ 16p13.3 0.0001964 0.408 KIAA0397 gene product IncytePD:1001871 Hs.7416 KIAA0397 17p13.3 0.0007462 0.410 major histocompatibility complex, class II, DQ beta 1 IncytePD:692201 Hs.73931 HLA-DQB1 6p21.3 8.58e-05 0.411 nuclear RNA export factor 1 IncytePD:1722870 Hs.323502 NXF1 11q12-q13 0.0002593 0.412 monoglyceride lipase IncytePD:2174920 Hs.6721 MGLL 3q21.3 0.0008986 0.412 chromosome 22 open reading frame 19 IncytePD:1712347 Hs.75361 C22orf19 22q12 0.0005474 0.415 RNA binding motif protein 6 IncytePD:1969094 Hs.173993 RBM6 3p21.3 0.0005978 0.415 Mdm2, transformed 3T3 cell double minute 2, p53 binding

protein (mouse) IncytePD:5505662 Hs.170027 MDM2 12q14.3-

2e-06 0.417 Homo sapiens mRNA; cDNA DKFZp762N156 (from clone DKFZp762N156)

IncytePD:695016 Hs.194397 7

2.74e-05 0.417 putative glialblastoma cell differentiation-related IncytePD:2190170 Hs.9194 GDBR1 9q34.3 0.0002029 0.418 RNA binding motif protein 14 IncytePD:231460 Hs.11170 RBM14 11q13.1 4.66e-05 0.420 interleukin enhancer binding factor 3, 90kDa IncytePD:1674263 Hs.256583 ILF3 19p13.2 5.83e-05 0.420 Hermansky-Pudlak syndrome 1 IncytePD:2203196 Hs.83951 HPS1 10q23.1-

q23.3 1.41e-05 0.421 Homo sapiens mRNA full length insert cDNA clone

EUROIMAGE 926491. IncytePD:1506962 Hs.98401 19

0.000109 0.421 chromosome 14 open reading frame 79 IncytePD:2056424 Hs.27183 C14orf79 14q32.33 4.1e-06 0.422 killer cell lectin-like receptor subfamily C, member 2 IncytePD:1231737 Hs.177605 KLRC2 12p13 3.24e-05 0.422 Homo sapiens cDNA FLJ30301 fis, clone BRACE2003217. IncytePD:1399368 Hs.285728 2 0.000127 0.422 hypothetical protein DJ667H12.2 IncytePD:1757834 Hs.21068 DJ667H12.2 1q32.1-

q41 0.0002652 0.422 KIAA0515 protein IncytePD:1752623 Hs.405891 KIAA0515 9q34.2 0.0001013 0.423 epidermal growth factor receptor pathway substrate 8 IncytePD:438438 Hs.2132 EPS8 12q23-q24 0.0001426 0.423 chromosome 21 open reading frame 4 IncytePD:2075469 Hs.284142 C21orf4 21q22.11 0.0008511 0.423 glutathione synthetase IncytePD:1962993 Hs.82327 GSS 20q11.2 2.06e-05 0.424 kinesin family member 13B IncytePD:2708596 Hs.15711 KIF13B 8p12 5.58e-05 0.424 biglycan IncytePD:1963963 Hs.821 BGN Xq28 0.0009419 0.424 zinc finger protein 266 IncytePD:619699 Hs.118281 ZNF266 19p13.2 6e-07 0.425 cold inducible RNA binding protein IncytePD:180164 Hs.119475 CIRBP 19p13.3 0.0006753 0.426 cytoplasmic FMR1 interacting protein 2 IncytePD:2832889 Hs.258503 CYFIP2 5q34 0.0002539 0.427 dystrobrevin, beta IncytePD:1844755 Hs.13451 DTNB 2p23-p22 0.0003028 0.427 limkain beta 2 IncytePD:1854253 Hs.288909 FLJ22471 12q24.31 0.0003263 0.427 similar to S. cerevisiae SSM4 IncytePD:1696606 Hs.20141 TEB4 5p15.2 1e-07 0.428 ESTs, Weakly similar to hypothetical protein FLJ20489

[Homo sapiens] [H.sapiens] IncytePD:777175 Hs.348501 8

5.5e-06 0.429 Rho-related BTB domain containing 1 IncytePD:2095275 Hs.15099 RHOBTB1 10q21.2 4.9e-06 0.430 Homo sapiens, clone IMAGE:5262734, mRNA IncytePD:2957644 Hs.296031 X 5.16e-05 0.430 Vam6/Vps39-like IncytePD:1674319 Hs.9452 VPS39 15q14 6.44e-05 0.430 kallikrein B, plasma (Fletcher factor) 1 IncytePD:2021730 Hs.1901 KLKB1 4q34-q35 0.0007952 0.430 hypothetical protein MGC39820 IncytePD:2802675 Hs.21415 MGC39820 3p14 0.0001205 0.431 Homo sapiens cDNA FLJ36248 fis, clone

THYMU2001989. IncytePD:2705256 Hs.41352 3

0.0002888 0.433 period homolog 1 (Drosophila) IncytePD:177171 Hs.68398 PER1 17p13.1-17p12

0.0003728 0.434 family with sequence similarity 13, member A1 IncytePD:1458366 Hs.177664 FAM13A1 4q22.1 6.76e-05 0.436 Rho guanine nucleotide exchange factor (GEF) 7 IncytePD:1468938 Hs.172813 ARHGEF7 13q33.3 8.35e-05 0.436 emerin (Emery-Dreifuss muscular dystrophy) IncytePD:1901168 Hs.2985 EMD Xq28 0.0003689 0.439 chromosome 18 open reading frame 1 IncytePD:1662893 Hs.153498 C18orf1 18p11.2 3.86e-05 0.442 hypothetical protein FLJ21016 IncytePD:1447393 Hs.289069 FLJ21016 1q42.12 0.0001329 0.443 mannose-6-phosphate receptor (cation dependent) IncytePD:1489979 Hs.134084 M6PR 12p13 2.6e-06 0.444 hypothetical protein FLJ10081 IncytePD:1215329 Hs.7871 FLJ10081 2p12-

p11.2 1.2e-05 0.445 PHD protein Jade-1 IncytePD:937508 Hs.238246 Jade-1 4q26-q27 0.0001076 0.445 collagen, type VIII, alpha 1 IncytePD:3118643 Hs.114599 COL8A1 3q12-

q13.1 0.000462 0.445 CDC14 (cell division cycle 14, S. cerevisiae) homolog B IncytePD:3438934 0.0007886 0.445 C-terminal binding protein 1 IncytePD:2822490 Hs.343926 CTBP1 4p16 6.46e-05 0.448 ESTs, Weakly similar to hypothetical protein FLJ22184

0.0006665 0.449 DKFZP434B0335 protein IncytePD:1909889 Hs.103931 DKFZP434B033 7q21.3 0.0003171 0.45 TATA box binding protein (TBP)-associated factor, RNA

polymerase I, C, 110kDa IncytePD:1868217 Hs.153022 TAF1C 16q24

0.0004337 0.452 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

IncytePD:1236828 Hs.332173 TLE2 19p13.3

0.0002405 0.453 kinesin family member 3B IncytePD:1659338 Hs.301206 KIF3B 20q11.1 0.0004193 0.453 ELG protein IncytePD:2241931 Hs.120963 HSA277841 17p13.3 0.0005979 0.453 ESTs IncytePD:2959963 Hs.189955 7 0.0003126 0.454 tumor necrosis factor receptor superfamily, member 14

(herpesvirus entry mediator) IncytePD:2121653 Hs.279899 TNFRSF14 1p36.3-

p36.2 0.0005061 0.456 catenin (cadherin-associated protein), alpha-like 1 IncytePD:2379808 Hs.58488 CTNNAL1 9q31.2 0.0001576 0.459 cyclin L2 IncytePD:2886955 Hs.143601 CCNL2 1p36.33 0.0008174 0.461 polycystic kidney disease 1-related IncytePD:1486385 Hs.209065 PKD1-like 1p34.2 2.19e-05 0.462 RNA binding motif protein 5 IncytePD:3596638 Hs.201675 RBM5 3p21.3 0.0003888 0.464 acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl

Coenzyme A thiolase) IncytePD:3888832 Hs.37 ACAT1 11q22.3-

q23.1 p < 1e-07 0.467 E1A binding protein p400 IncytePD:1967172 Hs.306094 EP400 12q24.33 1.58e-05 0.467 KIAA0310 gene product IncytePD:1880859 Hs.5716 KIAA0310 9q34.3 0.0001414 0.467 actin binding LIM protein 1 IncytePD:1722853 Hs.158203 ABLIM1 10q25 0.0008142 0.467 tripartite motif-containing 2 IncytePD:1267176 Hs.12372 TRIM2 4q31.23 0.0003383 0.468 Homo sapiens cDNA: FLJ22050 fis, clone HEP09454. IncytePD:2868216 Hs.173705 4 0.0006565 0.468 ESTs, Moderately similar to hypothetical protein FLJ20489

2e-07 0.470 numb homolog (Drosophila) IncytePD:1879023 Hs.78890 NUMB 14q24.3 0.0002054 0.470 aldehyde dehydrogenase 7 family, member A1 IncytePD:1811220 Hs.74294 ALDH7A1 5q31 0.0004613 0.470 ring finger protein 1 IncytePD:1879727 9.3e-05 0.471 retinoic acid induced 16 IncytePD:2395663 Hs.299148 RAI16 8p21.2 0.0001759 0.471 Incyte EST IncytePD:2418337 0.0006663 0.471 hypothetical protein F23149_1 IncytePD:1700814 Hs.152894 PD2 19q13.1 0.0006205 0.472 ret finger protein IncytePD:2708651 Hs.142653 RFP 6p22 0.0001666 0.475 spastic paraplegia 7, paraplegin (pure and complicated

autosomal recessive) IncytePD:1454012 Hs.296847 SPG7 16q24.3

2.99e-05 0.477 paired box gene 2 IncytePD:194662 Hs.155644 PAX2 10q22.1-q24.3

0.0003893 0.478 tetracycline transporter-like protein IncytePD:1856947 Hs.157145 TETRAN 4p16.3 0.0007073 0.480 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,

10, 42kDa IncytePD:2060704 Hs.198271 NDUFA10 2q37.3

0.0009288 0.480 KIAA0557 protein IncytePD:2698491 Hs.101414 KIAA0557 16p13.3 9.04e-05 0.481 nucleotide-sugar transporter similar to C. elegans sqv-7 IncytePD:1634141 Hs.90078 SQV7L 9q22.31 1.8e-06 0.482 hypothetical protein GL012 IncytePD:1943427 Hs.21379 GL012 9q34.11 6.1e-05 0.483 high density lipoprotein binding protein (vigilin) IncytePD:1348263 Hs.177516 HDLBP 2q37

9e-07 0.484 hypothetical protein FLJ11342 IncytePD:941442 Hs.266514 FLJ11342 3q13.13 0.000717 0.484 FLJ00005 protein IncytePD:1368493 Hs.367690 FLJ00005 15q22.33 0.0007349 0.484 hypothetical protein FLJ20274 IncytePD:2176218 8.12e-05 0.485 ESTs IncytePD:3971258 Hs.41840 2 0.0004537 0.487 collagen, type IX, alpha 3 IncytePD:1622535 Hs.53563 COL9A3 20q13.3 0.0009189 0.487 integrin, beta 2 (antigen CD18 (p95), lymphocyte function-

associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)

IncytePD:1871113 Hs.83968 ITGB2 21q22.3

3.91e-05 0.489 Homo sapiens mRNA; cDNA DKFZp434E109 (from clone DKFZp434E109)

IncytePD:1998708 Hs.279806 17

0.0003795 0.489 rab6 GTPase activating protein (GAP and centrosome-associated)

IncytePD:2620749 Hs.55099 GAPCENA 9q34.11

0.00043 0.489 ESTs IncytePD:2182201 Hs.49409 10 7e-07 0.490 Homo sapiens cDNA: FLJ23005 fis, clone LNG00396,

highly similar to AF055023 Homo sapiens clone 24723 mRNA sequence.

IncytePD:447148 Hs.58220 17

0.0002265 0.490 CD27-binding (Siva) protein IncytePD:2356635 Hs.112058 SIVA 14q32.33 5.5e-05 0.491 Homo sapiens cDNA FLJ34315 fis, clone FEBRA2008341. IncytePD:1734634 Hs.376655 14 4.9e-06 0.492 hypothetical protein DKFZp434M0331 IncytePD:2921913 Hs.48219 DKFZp434M033 12q23.2 0.0009549 0.492 multiple PDZ domain protein IncytePD:1601609 Hs.169378 MPDZ 9p24-p22 1.6e-06 0.493 hypothetical protein LOC90410 IncytePD:1552481 Hs.4187 LOC90410 17q11.1 9.27e-05 0.494 zinc finger protein 261 IncytePD:1752333 Hs.9568 ZNF261 Xq13.1 0.0001479 0.496 speckle-type POZ protein IncytePD:1737972 Hs.129951 SPOP 17q21.32 0.000557 0.496 heat shock protein 75 IncytePD:1616604 Hs.376253 TRAP1 16p13.3 6.24e-05 0.497 dimethylarginine dimethylaminohydrolase 2 IncytePD:1911142 Hs.247362 DDAH2 6p21.3 0.0004885 0.497 butyrophilin, subfamily 3, member A1 IncytePD:853243 Hs.284283 BTN3A1 6p22.1 0.0005268 0.497 growth arrest-specific 8 IncytePD:3687253 Hs.54877 GAS8 16q24.3 0.0006406 0.497 choline kinase IncytePD:1605233 Hs.77221 CHK 11q13.1 0.000647 0.497 cyclin-dependent kinase (CDC2-like) 10 IncytePD:1695859 Hs.77313 CDK10 16q24 0.0009941 0.497 hypothetical protein FLJ10948 IncytePD:1930954 Hs.34579 FLJ10948 1p32.3 0.0007884 0.498 B/K protein IncytePD:1922038 Hs.26971 LOC51760 16p13.11 1e-07 0.499 RAB28, member RAS oncogene family IncytePD:1457948 Hs.404189 RAB28 4p16.1 2.2e-06 0.500 CDC16 cell division cycle 16 homolog (S. cerevisiae) IncytePD:1413704 Hs.1592 CDC16 13q34 7.4e-06 0.501 phytanoyl-CoA hydroxylase (Refsum disease) IncytePD:4073867 Hs.172887 PHYH 10pter-

p11.2 8.59e-05 0.501 KIAA1228 protein IncytePD:2667106 Hs.306867 KIAA1228 7q36.3 1.06e-05 0.502 deiodinase, iodothyronine, type II IncytePD:2869983 Hs.154424 DIO2 14q24.2-

q24.3 0.0001815 0.503 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) IncytePD:1457718 Hs.93199 LSS 21q22.3 p < 1e-07 0.504 Homo sapiens cDNA FLJ30048 fis, clone ADRGL1000018. IncytePD:2466668 Hs.238956 17 7.54e-05 0.504 Homo sapiens cDNA FLJ30016 fis, clone 3NB692000429. IncytePD:1570161 Hs.14931 10 0.0003216 0.504 protein tyrosine phosphatase, receptor type, T IncytePD:3251982 Hs.225952 PTPRT 20q12-q13 0.0007741 0.506 KIAA0819 protein IncytePD:1910948 Hs.301866 KIAA0819 22q11.1 0.0003363 0.507 ESTs, Weakly similar to Solute carrier family 11 member 1

(natural resistance-associated macrophage protein 1); Natural resistance-associated macrophage protein; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 [Rattus

IncytePD:75549 Hs.22049 19

0.0001774 0.508 aldehyde dehydrogenase 6 family, member A1 IncytePD:1794046 Hs.293970 ALDH6A1 14q24.3 0.0002871 0.508 D-aspartate oxidase IncytePD:464406 Hs.174441 DDO 6q21 0.0001108 0.510 calponin 1, basic, smooth muscle IncytePD:2696735 Hs.21223 CNN1 19p13.2-

p13.1 0.0007847 0.510 hypothetical protein FLJ11806 IncytePD:2821840 Hs.323443 FLJ11806 14q31.3 0.0003645 0.511 KIAA0763 gene product IncytePD:1560143 Hs.4764 KIAA0763 3p25.1 0.000111 0.512 Pseudoautosomal GTP-binding protein-like IncytePD:1339234 Hs.372587 PGPL Xp22.33 0.000425 0.515 Incyte EST IncytePD:3105607 0.0008024 0.516 putative ankyrin-repeat containing protein IncytePD:2626237 Hs.4996 DKFZP564D166 17q23.3 0.000124 0.518 glucosidase I IncytePD:1555701 Hs.83919 GCS1 2p13-p12 2.91e-05 0.519 Human clone CE29 7.2 (CAC)n/(GTG)n repeat-containing

mRNA. IncytePD:3712928 Hs.133065 2

3.47e-05 0.519 interleukin 10 receptor, alpha IncytePD:1337981 Hs.327 IL10RA 11q23 0.0001037 0.519 hypothetical protein LOC284001 IncytePD:2751505 Hs.122075 LOC284001 17q25.3 0.0007593 0.520 adducin 1 (alpha) IncytePD:2736185 Hs.183706 ADD1 4p16.3 2.82e-05 0.521 tetratricopeptide repeat domain 3 IncytePD:1871722 Hs.118174 TTC3 21q22.2 0.0002391 0.521 ESTs IncytePD:2749823 Hs.187665 1 0.0003411 0.522 likely ortholog of mouse membrane bound C2 domain

containing protein IncytePD:1995174 Hs.8309 MBC2 12q13.13

0.0008604 0.522 CDC-like kinase 1 IncytePD:2446289 Hs.2083 CLK1 2q33 0.0001864 0.523 integrin, alpha E (antigen CD103, human mucosal

lymphocyte antigen 1; alpha polypeptide) IncytePD:3035468 Hs.851 ITGAE 17p13

0.0002284 0.523 glutaminyl-tRNA synthetase IncytePD:2446247 Hs.79322 QARS 3p21.3-p21.1

0.0006782 0.524 insulin receptor IncytePD:1349193 Hs.89695 INSR 19p13.3-p13.2

0.0007137 0.524 hypothetical protein FLJ20015 IncytePD:2043391 Hs.375614 FLJ20015 17q25 8e-06 0.525 golgi autoantigen, golgin subfamily b, macrogolgin (with

transmembrane signal), 1 IncytePD:1506093 Hs.7844 GOLGB1 3q13

6.13e-05 0.525 KIAA0809 protein IncytePD:1905478 Hs.105399 SRISNF2L 3p21.31 0.000104 0.525 KIAA0121 gene product IncytePD:1930294 Hs.155584 KIAA0121 3p25.2 0.0002543 0.525 centaurin, gamma 3 IncytePD:884855 Hs.286084 CENTG3 7q36.1 0.0004454 0.525 CDP-diacylglycerol--inositol 3-phosphatidyltransferase

(phosphatidylinositol synthase) IncytePD:3742316 Hs.121549 CDIPT 16p12.1

0.000624 0.526 MAX interacting protein 1 IncytePD:875567 Hs.118630 MXI1 10q24-q25 0.0007436 0.529 TAF7 RNA polymerase II, TATA box binding protein (TBP)-

associated factor, 55kDa IncytePD:1721917 Hs.155188 TAF7 5q31

0.0001357 0.530 F-box only protein 7 IncytePD:1911835 Hs.5912 FBXO7 22q12-q13 0.0004824 0.530 nephronophthisis 4 IncytePD:2655615 Hs.106487 NPHP4 1p36.22 0.0008145 0.530 KIAA0998 protein IncytePD:1444505 Hs.131525 KIAA0998 14q24.3 0.0007054 0.531 bromodomain adjacent to zinc finger domain, 2B IncytePD:553725 Hs.8383 BAZ2B 2q23-q24 0.0001292 0.532 phosphorylase kinase, alpha 2 (liver) IncytePD:2365335 Hs.54941 PHKA2 Xp22.2-

p22.1 0.0009271 0.534 eukaryotic translation initiation factor 3, subunit 1 alpha,

35kDa IncytePD:1998519 Hs.173987 EIF3S1 15q15.1

0.0009408 0.534 DnaJ (Hsp40) homolog, subfamily C, member 4 IncytePD:1603391 Hs.172847 DNAJC4 11q13 0.0001913 0.535 hypothetical protein FLJ20477 IncytePD:2313030 Hs.26994 FLJ20477 1p35.3 0.0001096 0.536 gonadotropin-releasing hormone 1 (leutinizing-releasing

hormone) IncytePD:1830640 Hs.82963 GNRH1 8p21-

p11.2 0.0004028 0.536 ESTs IncytePD:496874 Hs.125494 X 0.000196 0.538 myosin IXA IncytePD:2208002 Hs.23395 MYO9A 15q22-q23 0.0003918 0.538 ribosomal protein S6 kinase, 90kD, polypeptide 2 IncytePD:3421442 6.65e-05 0.539 chromosome 21 open reading frame 66 IncytePD:1358710 Hs.283771 C21orf66 21q21.3 0.0008997 0.539 ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog,

yeast) IncytePD:2122820 Hs.192853 UBE2G2 21q22.3

4.28e-05 0.541 membrane-bound transcription factor protease, site 1 IncytePD:1816514 Hs.75890 MBTPS1 16q24 0.0001669 0.542 Incyte EST IncytePD:2650203 0.0002392 0.542 HLA-B associated transcript 3 IncytePD:1942845 Hs.274348 BAT3 6p21.3 6e-07 0.544 chromosome 21 open reading frame 4 IncytePD:1710736 Hs.284142 C21orf4 21q22.11 4.66e-05 0.544 dihydroorotate dehydrogenase IncytePD:3815039 Hs.94925 DHODH 16q22 0.0001885 0.545 dedicator of cyto-kinesis 1 IncytePD:1671436 Hs.82295 DOCK1 10q26.13-

q26.3 0.0003888 0.545 peroxisome biogenesis factor 10 IncytePD:3115936 Hs.247220 PEX10 1p36.32 0.0004929 0.545 general transcription factor IIIA IncytePD:1527070 Hs.75113 GTF3A 13q12.3-

q13.1 5.95e-05 0.546 solute carrier family 10 (sodium/bile acid cotransporter

family), member 2 IncytePD:3698258 Hs.194783 SLC10A2 13q33

0.0004224 0.546 Incyte EST IncytePD:2542313 0.0003565 0.547 splicing factor 1 IncytePD:2655068 Hs.180677 SF1 11q13 1.2e-06 0.548 calcium channel, voltage-dependent, beta 2 subunit IncytePD:3517320 Hs.30941 CACNB2 10p12 0.0001565 0.548 DKFZP586P0123 protein IncytePD:1923483 Hs.376803 DKFZP586P012 11q13.3 0.0002402 0.548 Homo sapiens, Similar to hypothetical protein FLJ13639,

clone IMAGE:4310637, mRNA IncytePD:2372541 Hs.390401 13

0.0004823 0.548 golgi apparatus protein 1 IncytePD:1833213 Hs.78979 GLG1 16q22-q23 0.0005157 0.549 nucleotide binding protein IncytePD:944906 Hs.296422 NBP 17q12-q21 9.69e-05 0.550 WD repeat domain 22 IncytePD:1547366 Hs.284294 WDR22 14q23-

q24.1 1.7e-06 0.551 bromodomain containing 8 IncytePD:2992892 Hs.5464 BRD8 5q31 2.29e-05 0.553 hypothetical protein FLJ10824 IncytePD:1457726 Hs.375174 FLJ10824 10q11.22 0.0008758 0.553 hypothetical brain protein my038 IncytePD:1616072 Hs.374853 MY038 16p12.2 1.5e-06 0.554 E1A binding protein p400 IncytePD:2739049 Hs.306094 EP400 12q24.33 0.0005098 0.556 Homo sapiens clone FBD3 Cri-du-chat critical region

mRNA IncytePD:1910705 Hs.432862 2

0.0005541 0.556 KIAA0194 protein IncytePD:1429306 Hs.216958 KIAA0194 5q33.1 0.0006131 0.557 hypothetical protein LOC51321 IncytePD:2287941 Hs.268122 LOC51321 17q24.3 0.0004219 0.558 bromodomain containing 2 IncytePD:1362115 Hs.75243 BRD2 6p21.3 0.0007773 0.558 DKFZP547E1010 protein IncytePD:1730581 Hs.323817 DKFZP547E101 1q21.3 0.0001659 0.560 N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) IncytePD:1722844 Hs.50727 NAGLU 17q21 0.0007419 0.560 calcium channel, voltage-dependent, beta 1 subunit IncytePD:877744 Hs.635 CACNB1 17q21-q22 0.0009116 0.560 endothelial differentiation, lysophosphatidic acid G-protein-

coupled receptor, 4 IncytePD:1732445 Hs.122575 EDG4 19p12

3.88e-05 0.561 solute carrier family 35 (CMP-sialic acid transporter), member 1

IncytePD:1440433 Hs.82921 SLC35A1 6q15

0.0002869 0.562 interleukin 13 receptor, alpha 1 IncytePD:1556648 Hs.285115 IL13RA1 Xq24 0.0004353 0.562 hypothetical protein FLJ10569 IncytePD:1000585 Hs.5105 FLJ10569 8p21.3 0.0001145 0.563 SECIS binding protein 2 IncytePD:1877743 Hs.288141 SBP2 9q22.1 0.0002075 0.563 ESTs, Weakly similar to hypothetical protein FLJ20489

0.0002975 0.563 mitochondrial ribosomal protein S27 IncytePD:1870704 Hs.122669 MRPS27 5q13.1 0.0003484 0.564 two-pore channel 1, homolog IncytePD:589453 Hs.26440 KIAA1169 12q24.21 2e-07 0.566 zinc finger protein 161 homolog (mouse) IncytePD:2487368 Hs.156000 ZFP161 18pter-

p11.2 9e-05 0.566 splicing factor 3b, subunit 1, 155kDa IncytePD:1977 Hs.334826 SF3B1 2q33.1 0.0002112 0.566 chromosome 20 open reading frame 104 IncytePD:3444340 Hs.301055 C20orf104 20q11.22-

q11.23 0.0001417 0.567 polymerase (RNA) III (DNA directed) polypeptide F, 39

kDa IncytePD:1682994 Hs.128207 POLR3F 20p11.23

0.0008911 0.568 synaptopodin IncytePD:1923572 Hs.5307 KIAA1029 5q33.1 4.19e-05 0.569 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble IncytePD:1616328 Hs.284202 XPNPEP1 10q25.3 0.0001192 0.569 lecithin-cholesterol acyltransferase IncytePD:2395357 0.0001466 0.569 Williams Beuren syndrome chromosome region 21 IncytePD:1516990 Hs.182476 WBSCR21 7q11.23 3.16e-05 0.570 A kinase (PRKA) anchor protein (yotiao) 9 IncytePD:997782 Hs.58103 AKAP9 7q21-q22 0.0007135 0.570 MDN1, midasin homolog (yeast) IncytePD:1209813 Hs.76730 MDN1 6q15 4.3e-06 0.572 Homo sapiens cDNA: FLJ23013 fis, clone LNG00740. IncytePD:1911371 Hs.372737 19 0.0008776 0.572 activin A receptor, type I IncytePD:433573 Hs.150402 ACVR1 2q23-q24 0.0003214 0.574 spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2,

autosomal dominant, ataxin 2) IncytePD:664095 Hs.76253 SCA2 12q24

0.0007801 0.574 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

IncytePD:2288241 Hs.79089 SEMA4D 9q22-q31

1.7e-06 0.575 PHD finger protein 2 IncytePD:2790394 Hs.93868 PHF2 9q22.31 2.8e-06 0.575 bromodomain containing 8 IncytePD:2634206 Hs.5464 BRD8 5q31 0.0004756 0.577 natural killer cell receptor, immunoglobulin superfamily

member IncytePD:508322 Hs.81743 BY55 1q21.1

8.05e-05 0.578 coronin, actin binding protein, 2A IncytePD:2210264 Hs.44396 CORO2A 9q22.3 0.0008705 0.578 ESTs IncytePD:2754640 Hs.128104 19 5.48e-05 0.580 hypothetical protein FLJ20551 IncytePD:1924027 Hs.7994 FLJ20551 3p21.33 0.0002189 0.580 FERM, RhoGEF and pleckstrin domain protein 2 IncytePD:3406835 Hs.301283 FARP2 2q37.3 0.0003962 0.580 iduronate 2-sulfatase (Hunter syndrome) IncytePD:2776385 Hs.172458 IDS Xq28 0.000969 0.580 B-cell CLL/lymphoma 6 (zinc finger protein 51) IncytePD:1569189 Hs.155024 BCL6 3q27 0.0001523 0.581 hypothetical protein FLJ20003 IncytePD:1921914 Hs.258798 FLJ20003 10q26.13 0.0009593 0.582 hypothetical protein FLJ36090 IncytePD:1375185 Hs.42673 FLJ36090 5q23.2 0.0001845 0.583 oxidase (cytochrome c) assembly 1-like IncytePD:2055587 Hs.151134 OXA1L 14q11.2 0.0009837 0.583 thyroid stimulating hormone receptor IncytePD:1336836 Hs.123078 TSHR 14q31 0.0001227 0.584 potassium large conductance calcium-activated channel,

subfamily M beta member 3 IncytePD:2288482 Hs.276973 KCNMB3 3q26.3-

q27 0.000298 0.584 Incyte EST IncytePD:2243769 0.0003598 0.584 protein phosphatase 1B (formerly 2C), magnesium- IncytePD:2182353 Hs.5687 PPM1B 2p21

dependent, beta isoform 0.0004352 0.585 putative ankyrin-repeat containing protein IncytePD:1689764 Hs.4996 DKFZP564D166 17q23.3 0.0004037 0.586 Homo sapiens mRNA; cDNA DKFZp564O2364 (from clone

DKFZp564O2364) IncytePD:2296284 Hs.28893 17

2.69e-05 0.587 ESTs IncytePD:2208830 Hs.107845 2 0.0003371 0.588 Ac-like transposable element IncytePD:1926585 Hs.9933 ALTE Xp22.33 0.0001303 0.589 nuclear pore complex interacting protein IncytePD:2715266 Hs.251928 NPIP 16p13-p11 6.77e-05 0.590 multiple endocrine neoplasia I IncytePD:1693847 Hs.423348 MEN1 11q13 0.0001396 0.590 Human clone CE29 7.2 (CAC)n/(GTG)n repeat-containing

mRNA. IncytePD:3704132 Hs.133065 2

5.03e-05 0.591 MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein

IncytePD:789491 Hs.168481 MCM3AP 21q22.3

0.0006553 0.591 golgi associated, gamma adaptin ear containing, ARF binding protein 2

IncytePD:1749964 Hs.155546 GGA2 16p12

0.0008653 0.591 ESTs IncytePD:2557353 Hs.180295 1 0.000113 0.592 KIAA0563 gene product IncytePD:1365507 Hs.339808 KIAA0563 17q24.3 0.0007648 0.592 Human hbc647 mRNA sequence. IncytePD:1986919 Hs.24385 1 5.29e-05 0.594 U5 snRNP-specific protein, 200-KD IncytePD:1706690 Hs.246112 U5-200KD 2q11.1 0.0004991 0.594 cyclin-dependent kinase 3 IncytePD:1698903 Hs.100009 CDK3 17q22-qter 4.92e-05 0.596 PDZ domain containing 1 IncytePD:2674772 Hs.15456 PDZK1 1q21 7.05e-05 0.596 zinc finger protein 103 homolog (mouse) IncytePD:1843290 Hs.155968 ZFP103 2p11.2 7.9e-06 0.597 ubiquitin-conjugating enzyme E2L 3 IncytePD:1962592 Hs.108104 UBE2L3 22q11.21 0.0006596 0.597 ring finger protein 3 IncytePD:2860918 Hs.8834 RNF3 4p16.3 1.65e-05 0.598 myeloid/lymphoid or mixed-lineage leukemia (trithorax

homolog, Drosophila); translocated to, 2 IncytePD:1887185 Hs.114765 MLLT2 4q21

1.36e-05 0.601 hypothetical protein LOC125150 IncytePD:2556708 Hs.379903 LOC125150 17p11.2 2.49e-05 0.603 Incyte EST IncytePD:2821541 1.9e-06 0.604 Homo sapiens mRNA; cDNA DKFZp313P0917 (from clone

DKFZp313P0917) IncytePD:1753040 Hs.322851 9

8.73e-05 0.605 H-2K binding factor-2 IncytePD:1930602 Hs.347340 KBF2 9 0.000418 0.607 cathepsin O IncytePD:1689421 Hs.75262 CTSO 4q31-q32 7.5e-05 0.609 component of oligomeric golgi complex 8 IncytePD:2462127 Hs.224179 COG8 16q22.1 0.0003976 0.609 slit homolog 1 (Drosophila) IncytePD:750673 Hs.133466 SLIT1 10q23.3-

q24 3.77e-05 0.610 tropomodulin IncytePD:1721744 Hs.374849 TMOD 9q22.3 0.0004619 0.611 stromal cell protein IncytePD:334820 Hs.292154 LOC55974 1q21.3 9.1e-06 0.612 Homo sapiens cDNA FLJ36555 fis, clone TRACH2008716. IncytePD:1602726 Hs.96343 18 0.0002633 0.613 ras-like protein TC10 IncytePD:1698889 Hs.250697 TC10 2p21 0.0003412 0.613 hypothetical protein FLJ21877 IncytePD:584794 Hs.16063 FLJ21877 2p21 0.0002905 0.615 zinc finger protein 183 (RING finger, C3HC4 type) IncytePD:208836 Hs.64794 ZNF183 Xq25-q26 0.0003187 0.616 pituitary tumor-transforming 1 interacting protein IncytePD:728986 Hs.111126 PTTG1IP 21q22.3 0.0003199 0.616 nucleolar autoantigen (55kD) similar to rat synaptonemal

complex protein IncytePD:81490 Hs.446459 SC65 17q21.2

0.0004456 0.618 TIA1 cytotoxic granule-associated RNA binding protein-like 1

IncytePD:3031022 Hs.182741 TIAL1 10q

5.2e-06 0.619 butyrophilin, subfamily 3, member A2 IncytePD:1596154 Hs.87497 BTN3A2 6p22.1 0.0003062 0.622 myotubular myopathy 1 IncytePD:1560906 Hs.75302 MTM1 Xq28 0.0003502 0.622 mitogen-activated protein kinase kinase kinase kinase 4 IncytePD:1306496 Hs.3628 MAP4K4 2q11.2-

q12 0.0003472 0.625 Homo sapiens mRNA; cDNA DKFZp586F1322 (from clone

DKFZp586F1322) IncytePD:1793670 Hs.321056 11

0.0002764 0.626 cyclin D binding myb-like transcription factor 1 IncytePD:1637517 Hs.5671 DMTF1 7q21 1.9e-05 0.627 topoisomerase (DNA) II beta 180kDa IncytePD:1872327 Hs.75248 TOP2B 3p24 0.0003234 0.627 KIAA0182 protein IncytePD:1845755 Hs.75909 KIAA0182 16q24.1 0.0005837 0.627 ESTs IncytePD:3815547 Hs.445766 11 5.21e-05 0.628 pituitary tumor-transforming 1 interacting protein IncytePD:1651791 Hs.111126 PTTG1IP 21q22.3 0.0001925 0.628 component of oligomeric golgi complex 7 IncytePD:2874538 Hs.185807 COG7 16p12.3 2.97e-05 0.629 exostoses (multiple) 2 IncytePD:1965225 Hs.75334 EXT2 11p12-p11 7.16e-05 0.629 zinc finger protein 262 IncytePD:3409136 Hs.150390 ZNF262 1p32-p34 5.05e-05 0.631 ESTs, Moderately similar to hypothetical protein FLJ20489

0.000846 0.631 Homo sapiens, similar to olfactory receptor MOR145-2, clone IMAGE:5313643, mRNA

IncytePD:2024801 Hs.378911 7

0.0008952 0.631 hypothetical protein FLJ13441 IncytePD:2766987 Hs.232146 FLJ13441 5p15.33 7e-06 0.632 Incyte EST IncytePD:2160566 0.0007714 0.632 vesicle-associated membrane protein 3 (cellubrevin) IncytePD:1988078 Hs.66708 VAMP3 1p36.22 1.38e-05 0.633 NFS1 nitrogen fixation 1 (S. cerevisiae) IncytePD:1420364 Hs.194692 NFS1 20q11.21 0.0002966 0.633 transcription elongation factor A (SII), 2 IncytePD:676705 Hs.80598 TCEA2 20q13.33 1.27e-05 0.634 ribose 5-phosphate isomerase A (ribose 5-phosphate

epimerase) IncytePD:1863189 Hs.79886 RPIA 2p11.1

0.0003377 0.634 oral-facial-digital syndrome 1 IncytePD:2080379 Hs.6483 OFD1 Xp22.2-p22.3

0.0005749 0.634 COX15 homolog, cytochrome c oxidase assembly protein (yeast)

IncytePD:1976440 Hs.226581 COX15 10q24

3.12e-05 0.635 eukaryotic translation initiation factor 4A, isoform 2 IncytePD:2060081 0.0006143 0.636 Homo sapiens cDNA FLJ30843 fis, clone FEBRA2002574. IncytePD:1863561 Hs.350872 7 0.0001595 0.637 Incyte EST IncytePD:2685601 0.0004752 0.640 M-phase phosphoprotein 9 IncytePD:2508608 Hs.351230 MPHOSPH9 12q24.31 0.0007937 0.640 Incyte EST IncytePD:1602194 0.000829 0.640 argininosuccinate lyase IncytePD:3283759 Hs.61258 ASL 7cen-

q11.2 3.2e-06 0.641 phosphatidylinositol glycan, class F IncytePD:1557568 Hs.426142 PIGF 2p21-p16 2.38e-05 0.641 Incyte EST IncytePD:2878846 0.0009968 0.643 splicing factor (45kD) IncytePD:1782139 Hs.107001 SPF45 10p15.1 6e-07 0.647 Kruppel-type zinc finger (C2H2) IncytePD:2580149 Hs.142150 ZK1 19p13.13 0.0002581 0.647 zinc finger protein 165 IncytePD:1689436 Hs.55481 ZNF165 6p21.3 0.0001653 0.650 splicing factor, arginine/serine-rich 4 IncytePD:1967517 Hs.76122 SFRS4 1p35.2 0.0003771 0.654 SON DNA binding protein IncytePD:1624933 Hs.92909 SON 21q22.11 0.000454 0.654 cullin 4A IncytePD:1997406 Hs.183874 CUL4A 13q34 0.0004385 0.656 male-specific lethal 3-like 1 (Drosophila) IncytePD:1547409 Hs.88764 MSL3L1 Xp22.3 9.98e-05 0.657 bruno-like 6, RNA binding protein (Drosophila) IncytePD:407984 Hs.348342 BRUNOL6 15q24 7.89e-05 0.658 multiple endocrine neoplasia I IncytePD:1845962 Hs.423348 MEN1 11q13 0.000221 0.661 glycosyltransferase AD-017 IncytePD:1924806 Hs.283737 AD-017 3p21.31

0.0006742 0.663 ESTs IncytePD:372315 Hs.13957 19 0.0005092 0.664 zinc finger protein 263 IncytePD:2816931 Hs.182528 ZNF263 16p13.3 0.0005882 0.666 DKFZP434C171 protein IncytePD:2298081 Hs.209100 DKFZP434C171 5q33.1 0.0006154 0.666 B lymphoma Mo-MLV insertion region (mouse) IncytePD:1985881 Hs.380403 BMI1 10p11.23 3.45e-05 0.667 zinc finger protein 211 IncytePD:601975 Hs.15110 ZNF211 19q13.4 0.0002439 0.668 chromosome 20 open reading frame 4 IncytePD:1342448 Hs.11314 C20orf4 20pter-q12 0.0004622 0.668 disrupted in bipolar disorder 1 IncytePD:1577463 Hs.120824 DIBD1 11q23 0.0003695 0.671 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA

helicase, 68kDa) IncytePD:2057719 Hs.76053 DDX5 17q21

0.0006089 0.672 suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor)

IncytePD:1977875 Hs.194208 SNT-2 6p21.1

6.77e-05 0.676 ESTs, Weakly similar to hypothetical protein FLJ20489 [Homo sapiens] [H.sapiens]

IncytePD:2447969 Hs.352340 5

0.0006432 0.676 splicing factor, arginine/serine-rich 11 IncytePD:2862646 Hs.433581 SFRS11 1p31 0.000269 0.678 death associated transcription factor 1 IncytePD:1655225 Hs.155313 DATF1 20q13.33 0.0009712 0.681 mannosidase, beta A, lysosomal IncytePD:1805840 Hs.115945 MANBA 4q22-q25 3.69e-05 0.685 deformed epidermal autoregulatory factor 1 (Drosophila) IncytePD:1394322 Hs.6574 DEAF1 11p15.5 0.0009962 0.689 checkpoint suppressor 1 IncytePD:2362945 Hs.211773 CHES1 14q24.3-

q31 7.01e-05 0.691 pinin, desmosome associated protein IncytePD:1793943 Hs.44499 PNN 14q13.2 0.0007702 0.692 phospholipase A2, group VI (cytosolic, calcium-

independent) IncytePD:1849872 Hs.120360 PLA2G6 22q13.1

0.0008762 0.692 Homo sapiens mRNA from chromosome 5q21-22, clone:843Ex.

IncytePD:2666301 Hs.182723 5

0.0002158 0.694 ATPase, Class II, type 9B IncytePD:1454703 Hs.91471 ATP9B 18q23 0.0003524 0.694 spindlin-like protein 2 IncytePD:2522604 Hs.82577 SPIN2 Xp11.23-

p11.21 0.0006968 0.695 hypothetical protein FLJ20604 IncytePD:956848 Hs.55781 FLJ20604 3p24.1 0.0009252 0.698 ESTs IncytePD:2749990 Hs.188910 1 0.0008645 0.700 phosphoribosylformylglycinamidine synthase (FGAR

amidotransferase) IncytePD:2965687 Hs.105478 PFAS 17p13

0.0002984 0.701 RNA helicase-related protein IncytePD:2132758 Hs.8765 RNAHP 17q24.1 0.0005932 0.702 pancreatic lipase-related protein 1 IncytePD:2084515 Hs.73923 PNLIPRP1 10q26.11 0.0004322 0.703 sirtuin (silent mating type information regulation 2

homolog) 1 (S. cerevisiae) IncytePD:471870 Hs.31176 SIRT1 10q22.1

0.0005605 0.703 hypothetical protein FLJ10900 IncytePD:587420 Hs.16277 FLJ10900 7q11.21 0.0003551 0.704 bladder cancer overexpressed protein IncytePD:2174773 Hs.125830 BLOV1 12q15 1.08e-05 0.710 ubiquitin ligase E3 alpha-II IncytePD:1865148 Hs.15303 KIAA0349 6p21.1 9.85e-05 0.711 RAN binding protein 17 IncytePD:3557353 Hs.15032 RANBP17 5q34 0.0001373 0.713 Homo sapiens cDNA FLJ39218 fis, clone OCBBF2006660. IncytePD:2954670 Hs.29406 3 0.0004467 0.724 ESTs IncytePD:3407735 Hs.116424 16 0.0006089 0.726 KIAA0036 gene product IncytePD:1863428 Hs.169387 KIAA0036 3q13.33 0.0002728 0.730 ESTs IncytePD:2843672 Hs.404112 15 0.0001182 0.739 Homo sapiens, clone IMAGE:3875012, mRNA IncytePD:1817969 Hs.17872 12 5.35e-05 0.740 tetratricopeptide repeat domain 4 IncytePD:213516 Hs.5990 TTC4 1p31.3 0.000655 0.743 limkain b1 IncytePD:2610052 Hs.432741 LKAP 16p13.13 0.000377 0.752 insulin-like growth factor 1 receptor IncytePD:2597262 Hs.239176 IGF1R 15q25-q26 0.0007998 0.756 chromosome 14 open reading frame 117 IncytePD:2652746 Hs.103189 C14orf117 14q24.1 3.81e-05 0.769 TATA box binding protein IncytePD:1995841 Hs.1100 TBP 6q27 0.0004634 0.769 DKFZP586G011 protein IncytePD:1962827 Hs.234265 LAP1B 1q24.2 0.0009534 1.345 DiGeorge syndrome critical region gene 11 IncytePD:4412006 Hs.83775 DGCR11 22q11.21 0.0006473 1.378 transporter 2, ATP-binding cassette, sub-family B

(MDR/TAP) IncytePD:3473060 Hs.502 TAP2 6p21.3

0.0002459 1.435 ESTs, Weakly similar to NAL2_HUMAN NACHT-, LRR- and PYD-containing protein 2 (Nucleotide-binding site protein 1) [H.sapiens]

IncytePD:2751667 Hs.285363 19

7.53e-05 1.475 chromosome 1 open reading frame 19 IncytePD:1665871 Hs.32058 C1orf19 1q25 0.0009685 1.530 phospholipid scramblase 1 IncytePD:1611623 Hs.198282 PLSCR1 3q23 0.000533 1.585 sulfotransferase family, cytosolic, 2B, member 1 IncytePD:2621547 Hs.94581 SULT2B1 19q13.3 0.0007282 1.618 ribosomal protein L37a IncytePD:2452713 Hs.296290 RPL37A 2q35 0.0001724 1.621 RAB22A, member RAS oncogene family IncytePD:775737 Hs.288968 RAB22A 20q13.31 0.0002278 1.632 T cell receptor delta locus IncytePD:2556177 Hs.2014 TRD@ 14q11.2 0.0005682 1.634 very low density lipoprotein receptor IncytePD:1690952 Hs.73729 VLDLR 9p24 0.0008102 1.650 hypothetical protein FLJ32115 IncytePD:2374046 Hs.293902 FLJ32115 12p13.1 0.0007907 1.686 myosin, heavy polypeptide 8, skeletal muscle, perinatal IncytePD:3288518 Hs.113973 MYH8 17p13.1 0.0007006 1.690 interleukin 13 receptor, alpha 1 IncytePD:1476267 Hs.285115 IL13RA1 Xq24 0.0009648 1.696 myosin IB IncytePD:2206062 Hs.121576 MYO1B 2q12-q34 4.92e-05 1.710 Homo sapiens, clone IMAGE:4498705, mRNA IncytePD:2956730 Hs.180908 10 0.000646 1.720 Homo sapiens mRNA; cDNA DKFZp586F2224 (from clone

DKFZp586F2224) IncytePD:1468512 Hs.3843 3

0.0002218 1.731 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included)

IncytePD:1854558 Hs.69747 FUT1 19q13.3

0.0002159 1.745 cyclin-dependent kinase 5, regulatory subunit 1 (p35) IncytePD:1741702 Hs.93597 CDK5R1 17q11.2 0.0003288 1.782 KIAA1194 IncytePD:2221768 Hs.5801 KIAA1194 5q35.3 0.000559 1.787 Homo sapiens cDNA FLJ13427 fis, clone PLACE1002477. IncytePD:599050 Hs.88605 2 0.0004171 1.794 KIAA1295 protein IncytePD:1208611 Hs.26204 KIAA1295 5q35.2 0.0001641 1.804 Spi-B transcription factor (Spi-1/PU.1 related) IncytePD:1561204 Hs.192861 SPIB 19q13.3-

q13.4 0.000388 1.820 origin recognition complex, subunit 2-like (yeast) IncytePD:588671 Hs.41694 ORC2L 2q33 0.0006503 1.820 BH3 interacting domain death agonist IncytePD:2782033 Hs.172894 BID 22q11.1 0.0001144 1.824 transmembrane 4 superfamily member 5 IncytePD:1634851 Hs.184194 TM4SF5 17p13.3 0.0002225 1.832 heat shock 70kDa protein 1-like IncytePD:535732 Hs.80288 HSPA1L 6p21.3 0.0002758 1.852 major histocompatibility complex, class II, DM beta IncytePD:735149 Hs.1162 HLA-DMB 6p21.3 4.71e-05 1.855 ATP-binding cassette, sub-family A (ABC1), member 1 IncytePD:1467253 Hs.211562 ABCA1 9q31.1 0.0001788 1.857 epimorphin IncytePD:3438987 Hs.99865 EPIM 7 5.83e-05 1.870 cyclin B1 IncytePD:2877029 Hs.23960 CCNB1 5q12 0.0003289 1.872 transmembrane 7 superfamily member 1 (upregulated in

kidney) IncytePD:830684 Hs.15791 TM7SF1 1q42-q43

0.000362 1.876 ovo-like 1(Drosophila) IncytePD:3534569 Hs.97905 OVOL1 11q13 0.0001911 1.878 kinesin family member 14 IncytePD:4511928 Hs.3104 KIF14 1pter-

q31.3 0.0003457 1.883 8-oxoguanine DNA glycosylase IncytePD:3033131 Hs.96398 OGG1 3p26.2 0.0004562 1.894 paired box gene 8 IncytePD:1440279 Hs.73149 PAX8 2q12-q14

0.0002306 1.895 sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase)

IncytePD:5385159 Hs.114316 SIAT8C 18q21.2

0.0005365 1.910 cadherin 15, M-cadherin (myotubule) IncytePD:2517367 Hs.148090 CDH15 16q24.3 0.0004766 1.916 heterogeneous nuclear ribonucleoprotein A/B IncytePD:2194749 Hs.81361 HNRPAB 5q35.3 0.0005328 1.941 fibronectin 1 IncytePD:3553729 Hs.287820 FN1 2q34 0.0009202 1.969 putative G protein coupled receptor IncytePD:2480493 Hs.37196 GPR 15q13.3 0.0001508 1.975 a disintegrin and metalloproteinase domain 11 IncytePD:2602282 Hs.6088 ADAM11 17q21.3 0.0006621 2.012 MyoD family inhibitor IncytePD:2645911 Hs.153203 MDFI 6p21 0.0002838 2.015 Homo sapiens cDNA FLJ23705 fis, clone HEP11066. IncytePD:2105590 Hs.49136 8 0.0005045 2.020 hypothetical protein FLJ25416 IncytePD:2791966 Hs.165607 FLJ25416 11q13.5 0.0004816 2.026 Homo sapiens cDNA FLJ37042 fis, clone BRACE2011947. IncytePD:1208908 Hs.432542 5 0.0007633 2.027 hypothetical protein FLJ13659 IncytePD:2781142 Hs.301651 FLJ13659 19p12 0.0002519 2.030 Incyte EST IncytePD:1618195 2.6e-06 2.060 hypothetical protein FLJ10116 IncytePD:2381415 Hs.79741 FLJ10116 2q35 0.0008096 2.071 mitogen-activated protein kinase kinase kinase 10 IncytePD:2155126 Hs.30223 MAP3K10 19q13.2 0.0002905 2.079 polymyositis/scleroderma autoantigen 1, 75kDa IncytePD:1473617 Hs.91728 PMSCL1 4q27 0.0009205 2.084 KIAA0767 protein IncytePD:2706448 Hs.95180 KIAA0767 22q13.31 0.0002545 2.105 KIAA1357 protein IncytePD:1266388 Hs.170162 KIAA1357 6q23.3 0.0007599 2.108 retinal G protein coupled receptor IncytePD:753651 Hs.1544 RGR 10q23 0.0007919 2.109 synuclein, beta IncytePD:926957 Hs.90297 SNCB 5q35 0.0004233 2.132 HSPC135 protein IncytePD:3728524 Hs.127496 HSPC135 3q13.2 0.0001004 2.139 ESTs IncytePD:1888036 Hs.427773 2 5.95e-05 2.162 v-ral simian leukemia viral oncogene homolog A (ras

related) IncytePD:1981716 Hs.6906 RALA 7p22-p15

0.0006342 2.188 Homo sapiens, clone IMAGE:5206119, mRNA IncytePD:3136873 Hs.270312 17 3e-04 2.198 corticotropin releasing hormone receptor 1 IncytePD:2494107 Hs.79117 CRHR1 17q12-q22 0.0008073 2.200 hypothetical protein MGC17347 IncytePD:1866093 Hs.36828 MGC17347 9q13 0.0007275 2.212 Incyte EST IncytePD:2800618 0.0001034 2.249 chromosome 12 open reading frame 5 IncytePD:566860 Hs.24792 C12orf5 12p13.3 0.0008376 2.259 Homo sapiens cDNA: FLJ23454 fis, clone HSI06959. IncytePD:1601279 Hs.25717 3 0.0003092 2.279 solute carrier family 16 (monocarboxylic acid transporters),

member 1 IncytePD:733668 Hs.75231 SLC16A1 1p12

0.0001549 2.280 hypothetical protein FLJ11175 IncytePD:3475944 Hs.33368 FLJ11175 15q26.1 0.0006617 2.291 lysophospholipase I IncytePD:1811857 Hs.12540 LYPLA1 8q11.23 0.0004173 2.299 nuclear receptor subfamily 4, group A, member 3 IncytePD:1919520 Hs.80561 NR4A3 9q22 0.00064 2.316 Incyte EST IncytePD:1217695 0.0003614 2.320 uroplakin 1A IncytePD:1708315 Hs.159309 UPK1A 19q13.13 0.0008168 2.323 centrosomal protein 2 IncytePD:1706039 Hs.27910 CEP2 20q11.22-

q12 0.0006759 2.334 general transcription factor IIE, polypeptide 1, alpha 56kDa IncytePD:3203823 Hs.145381 GTF2E1 3q21-q24 0.0004855 2.337 zinc finger protein 226 IncytePD:622184 Hs.145956 ZNF226 19q13.2 0.0004186 2.346 ESTs IncytePD:2676494 Hs.433013 8 0.0009561 2.351 hypothetical protein BC009115 IncytePD:1413132 Hs.116602 LOC92935 2q33.1 0.0006151 2.353 SAC1 suppressor of actin mutations 1-like (yeast) IncytePD:5495255 Hs.5867 SACM1L 3p21.3 0.0007681 2.366 kinesin family member 5A IncytePD:5267178 Hs.192760 KIF5A 12q13 0.0005415 2.373 zymogen granule protein 16 IncytePD:1226538 Hs.184507 ZG16 16p12.1 0.0007225 2.376 frizzled homolog 7 (Drosophila) IncytePD:2736837 Hs.173859 FZD7 2q33 0.0009784 2.378 ocular albinism 1 (Nettleship-Falls) IncytePD:2808289 Hs.74124 OA1 Xp22.3 0.000447 2.389 basic leucine zipper nuclear factor 1 (JEM-1) IncytePD:2459178 Hs.158205 BLZF1 1q24 0.0009535 2.394 ESTs IncytePD:2590267 Hs.445376 0.0001741 2.399 cyclin-dependent kinase 5, regulatory subunit 1 (p35) IncytePD:2612515 Hs.93597 CDK5R1 17q11.2 0.0007724 2.401 slingshot 3 IncytePD:2020433 Hs.29173 SSH-3 11q13.1 0.0009061 2.411 DKFZP434F091 protein IncytePD:2886732 Hs.30488 DKFZP434F091 3p25.3 0.0008546 2.425 Homo sapiens, clone MGC:43036 IMAGE:4839025,

mRNA, complete cds IncytePD:2937340 Hs.97717 7

0.0007917 2.449 Homo sapiens mRNA; cDNA DKFZp564O1016 (from clone DKFZp564O1016)

IncytePD:2844112 Hs.15787 3

0.0008289 2.464 Human S6 A-5 mRNA expressed in chromosome 6-suppressed melanoma cells.

IncytePD:2635559 Hs.292801 16

0.0008083 2.468 Homo sapiens clone 24411 mRNA sequence IncytePD:1842626 Hs.20952 12 0.000508 2.490 Incyte EST IncytePD:5288736 0.0006189 2.508 matrix metalloproteinase 11 (stromelysin 3) IncytePD:1996013 Hs.155324 MMP11 22q11.23 p < 1e-07 2.511 Homo sapiens, Similar to hypothetical protein B430208I01,

clone IMAGE:5181522, mRNA, partial cds IncytePD:1987866 Hs.106771 5

0.0009559 2.521 ESTs IncytePD:3187892 Hs.120224 8 0.0008542 2.532 mannan-binding lectin serine protease 2 IncytePD:2513394 Hs.119983 MASP2 1p36.3-

p36.2 0.0006682 2.572 Kruppel-like factor 7 (ubiquitous) IncytePD:2644952 Hs.21599 KLF7 2q32 0.0008424 2.572 phafin 2 IncytePD:2556746 Hs.29724 FLJ13187 8q22.1 0.0005929 2.584 RP42 homolog IncytePD:1379662 Hs.104613 RP42 3q26.3 0.0004588 2.585 Homo sapiens cDNA FLJ34400 fis, clone

HCHON2001434, highly similar to NADH-UBIQUINONE OXIDOREDUCTASE 42 KDA SUBUNIT, MITOCHONDRIAL PRECURSOR (EC 1.6.5.3).

IncytePD:2107343 Hs.380035 2

0.0001706 2.593 ADP-ribosylation-like factor 8 IncytePD:3367716 Hs.220929 ARL8 10p12.33 0.0008816 2.594 hypothetical protein FLJ25348 IncytePD:394219 Hs.62604 FLJ25348 1p34.3 0.0005937 2.616 adrenergic, beta-3-, receptor IncytePD:1722947 Hs.2549 ADRB3 8p12-

p11.2 0.0002706 2.625 proteasome (prosome, macropain) subunit, beta type, 2 IncytePD:1986028 Hs.432607 PSMB2 1p34.2 0.0005172 2.628 liver mitochondrial glutaminase IncytePD:1781632 Hs.325443 GA 12q13 0.0005866 2.634 ESTs, Moderately similar to neuronal thread protein [Homo

sapiens] [H.sapiens] IncytePD:1293515 Hs.97109 1

0.000892 2.638 fibromodulin IncytePD:1999120 Hs.230 FMOD 1q32 0.000617 2.640 peroxisomal farnesylated protein IncytePD:1819287 Hs.168670 PXF 1q22 0.0008643 2.660 Homo sapiens clone 24400 mRNA sequence IncytePD:2886421 Hs.159528 2 0.0008067 2.677 Wiskott-Aldrich syndrome-like IncytePD:3176244 Hs.170065 WASL 7q31.3 0.0006619 2.678 DKFZP566I1024 protein IncytePD:1626927 Hs.279696 DKFZP566I102 7q11.1 0.0005233 2.680 luteinizing hormone beta polypeptide IncytePD:395798 Hs.154704 LHB 19q13.32 0.0009242 2.720 furin (paired basic amino acid cleaving enzyme) IncytePD:1219315 Hs.59242 FURIN 15q26.1 0.0004307 2.723 periphilin 1 IncytePD:2780529 Hs.281428 PPHLN1 12q12 0.0006016 2.727 receptor (TNFRSF)-interacting serine-threonine kinase 1 IncytePD:2056711 Hs.296327 RIPK1 6p25.2 0.000779 2.752 soluble liver antigen/liver pancreas antigen IncytePD:3231844 Hs.161436 SLA/LP 4p15.31 0.000471 2.758 potassium large conductance calcium-activated channel, IncytePD:1674220 Hs.93841 KCNMB1 5q34

subfamily M, beta member 1 0.0008933 2.779 Homo sapiens, clone IMAGE:4829637, mRNA IncytePD:2751837 Hs.334677 4 0.0009478 2.780 Homo sapiens cDNA FLJ31114 fis, clone IMR322000379. IncytePD:2176387 Hs.44441 X 0.0006358 2.788 hypothetical cardiac/skeletal muscle-expressed ORF IncytePD:3028712 Hs.50820 LOC92235 1q22-q24 0.0008205 2.823 pronapsin A IncytePD:2589487 Hs.322854 NAP1 19q13.33 0.00015 2.824 NS1-binding protein IncytePD:1265676 Hs.197298 NS1-BP 1q25.1-

q31.1 0.000203 2.850 tumor necrosis factor (ligand) superfamily, member 11 IncytePD:794703 Hs.115770 TNFSF11 13q14 0.0006491 2.861 lymphocyte antigen 6 complex, locus H IncytePD:2209586 Hs.159590 LY6H 8q24.3 0.0008829 2.864 serine dehydratase IncytePD:1902152 Hs.76751 SDS 12q24.21 0.0002889 2.885 caveolin 1, caveolae protein, 22kDa IncytePD:4271973 Hs.74034 CAV1 7q31.1 0.0008227 2.889 agouti related protein homolog (mouse) IncytePD:3127152 Hs.104633 AGRP 16q22 0.0009354 2.915 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 IncytePD:1287093 Hs.104576 CHST1 11p11.2-

p11.1 0.0006589 2.956 prolactin IncytePD:1759948 Hs.1905 PRL 6p22.2-

p21.3 0.0007223 2.970 islet amyloid polypeptide IncytePD:2077090 Hs.142255 IAPP 12p12.3-

p12.1 0.0004247 2.990 piwi-like 2 (Drosophila) IncytePD:2783496 Hs.58248 HIWI2 11q21 7.46e-05 2.992 solute carrier family 16 (monocarboxylic acid transporters),

member 1 IncytePD:1981569 Hs.75231 SLC16A1 1p12

0.0006965 3.004 carcinoembryonic antigen-related cell adhesion molecule 3 IncytePD:3802206 Hs.11 CEACAM3 19q13.2 6.5e-06 3.011 tripartite motif-containing 16 IncytePD:1996011 Hs.241305 TRIM16 17p11.2 0.0009009 3.033 interleukin 11 IncytePD:3138407 Hs.1721 IL11 19q13.3-

q13.4 0.0004451 3.036 hypothetical protein FLJ21079 IncytePD:1909443 Hs.16512 FLJ21079 6q13 0.0009939 3.100 runt-related transcription factor binding protein 2 IncytePD:2792711 Hs.82210 RUNXBP2 8p11 8.44e-05 3.141 parathyroid hormone-like hormone IncytePD:1556168 Hs.89626 PTHLH 12p12.1-

p11.2 0.0008474 3.161 protein phosphatase 1, regulatory (inhibitor) subunit 13B IncytePD:2193506 Hs.6162 PPP1R13B 14q32.33 0.000872 3.190 extracellular matrix protein 1 IncytePD:1965806 Hs.81071 ECM1 1q21 0.0007025 3.191 ESTs IncytePD:2846949 Hs.405184 4 0.0004486 3.194 gap junction protein, beta 5 (connexin 31.1) IncytePD:1923289 Hs.198249 GJB5 1p35.1 0.0008497 3.194 paired mesoderm homeo box 1 IncytePD:3118038 Hs.443452 PMX1 1q24 0.0009776 3.202 coenzyme Q7 homolog, ubiquinone (yeast) IncytePD:1683318 Hs.157113 COQ7 16p13.11-

p12.3 0.0009227 3.217 hypothetical protein DKFZp566D234 IncytePD:3149777 Hs.32452 DKFZp566D234 4q32.3 0.0009491 3.226 KIAA0532 protein IncytePD:2201626 Hs.21077 KIAA0532 8q22.2 0.0007173 3.238 KIAA0363 protein IncytePD:1799810 Hs.96633 KIAA0363 7p12.3 0.0003699 3.245 secretin receptor IncytePD:2216503 Hs.2199 SCTR 2q14.1 0.0004979 3.247 chromosome 4 open reading frame 1 IncytePD:1433576 Hs.270956 C4orf1 4p13-p12 0.0005988 3.254 ets variant gene 2 IncytePD:1320685 Hs.194061 ETV2 19q13.11 0.0007444 3.264 Homo sapiens, clone MGC:41943 IMAGE:5296763,

mRNA, complete cds IncytePD:2683763 Hs.351119 7

0.0005255 3.272 Homo sapiens cDNA: FLJ23006 fis, clone LNG00414. IncytePD:1677988 Hs.79881 3 0.0005451 3.276 achaete-scute complex-like 1 (Drosophila) IncytePD:2149404 Hs.1619 ASCL1 12q22-q23 0.0006683 3.281 gamma-aminobutyric acid (GABA) A receptor, alpha 3 IncytePD:4400865 Hs.123024 GABRA3 Xq28 0.0006418 3.301 hypothetical protein DKFZp761D221 IncytePD:1415864 Hs.20935 DKFZp761D221 1p31.2 0.0004261 3.304 Homo sapiens clone 24566 mRNA sequence IncytePD:5265684 Hs.133342 2 0.0009593 3.306 ESTs IncytePD:543027 Hs.46762 20 0.0006759 3.309 LIM domain only 1 (rhombotin 1) IncytePD:4758453 Hs.1149 LMO1 11p15 0.0009898 3.323 T-box 5 IncytePD:2590504 Hs.50947 TBX5 12q24.1 0.0002471 3.326 chemokine (C-C motif) ligand 17 IncytePD:2938757 Hs.66742 CCL17 16q13 0.0008019 3.345 KIAA1719 protein IncytePD:4464644 Hs.296770 KIAA1719 3p24-p23 0.0005917 3.351 KIAA0450 gene product IncytePD:2799177 Hs.170156 KIAA0450 1p36.32 0.0006443 3.355 interleukin 1 receptor-like 1 IncytePD:313081 Hs.66 IL1RL1 2q12 0.0005533 3.357 fyn-related kinase IncytePD:1358415 Hs.89426 FRK 6q21-

q22.3 0.0001405 3.385 Homo sapiens, clone IMAGE:4106329, mRNA IncytePD:832718 Hs.351201 22 0.000127 3.414 Homo sapiens, clone IMAGE:3923185, mRNA IncytePD:4217059 Hs.354068 18 0.000912 3.426 synuclein, gamma (breast cancer-specific protein 1) IncytePD:1317411 Hs.349470 SNCG 10q23.2-

q23.3 0.0004732 3.438 neurexophilin 1 IncytePD:624334 Hs.343660 NXPH1 7p22 0.0004468 3.478 cofactor required for Sp1 transcriptional activation, subunit

2, 150kDa IncytePD:3969924 Hs.407604 CRSP2 Xp11.4-

p11.2 0.00099 3.484 nerve growth factor, beta polypeptide IncytePD:2887215 Hs.2561 NGFB 1p13.1 0.0009972 3.520 acetylcholinesterase (YT blood group) IncytePD:5035992 Hs.154495 ACHE 7q22 0.0008207 3.526 titin-cap (telethonin) IncytePD:3030770 Hs.343603 TCAP 17q12 0.0006457 3.537 likely ortholog of mouse mitogen activated protein kinase

binding proten 1 IncytePD:2346641 Hs.259729 MAPKBP1 15q14

0.0009581 3.550 deoxynucleotidyltransferase, terminal IncytePD:2611448 Hs.397294 DNTT 10q23-q24 0.0007769 3.553 plectin 1, intermediate filament binding protein 500kDa IncytePD:1907232 Hs.79706 PLEC1 8q24 0.000917 3.631 ATPase, H+/K+ exchanging, beta polypeptide IncytePD:2938310 Hs.813 ATP4B 13q34 0.0004242 3.650 ESTs IncytePD:3645701 Hs.120276 6 0.0008197 3.656 cartilage intermediate layer protein, nucleotide

pyrophosphohydrolase IncytePD:1998288 Hs.151407 CILP 15q22

0.0007358 3.668 cadherin 6, type 2, K-cadherin (fetal kidney) IncytePD:2406795 Hs.32963 CDH6 5p15.1-p14

0.0009011 3.733 potassium large conductance calcium-activated channel, subfamily M, alpha member 1

IncytePD:2586677 Hs.89463 KCNMA1 10q22-q23

0.0006427 3.738 chitinase 1 (chitotriosidase) IncytePD:1925077 Hs.91093 CHIT1 1q31-q32 9.01e-05 3.775 claudin 1 IncytePD:2795896 Hs.7327 CLDN1 3q28-q29 0.0009393 3.786 Homo sapiens cDNA FLJ37183 fis, clone BRALZ2001445. IncytePD:4729574 Hs.333522 1 0.0008111 3.793 chemokine (C-C motif) ligand 13 IncytePD:1977527 Hs.11383 CCL13 17q11.2 0.000664 3.808 A kinase (PRKA) anchor protein 4 IncytePD:4923083 Hs.97633 AKAP4 Xp11.2 0.0007117 3.879 ESTs IncytePD:1686856 Hs.98367 8 4.08e-05 3.899 Incyte EST IncytePD:1260330 0.0009456 3.974 interleukin 4 IncytePD:4347370 Hs.73917 IL4 5q31.1 0.0006208 3.990 insulin IncytePD:2076748 Hs.89832 INS 11p15.5 0.0007759 4.039 KIAA1855 protein IncytePD:1269538 Hs.343820 KIAA1855 6p21.1 0.0006028 4.063 epiregulin IncytePD:443631 Hs.115263 EREG 4q21.1 6.76e-05 4.092 visinin-like 1 IncytePD:1741701 Hs.2288 VSNL1 2p24.3 0.000446 4.114 solute carrier family 10 (sodium/bile acid cotransporter IncytePD:5034123 Hs.952 SLC10A1 14q24.1

family), member 1 0.0008518 4.188 arachidonate 12-lipoxygenase IncytePD:3472502 Hs.1200 ALOX12 17p13.1 0.0006471 4.312 protocadherin 8 IncytePD:4090868 Hs.19492 PCDH8 13q14.3-

q21.1 0.000714 4.390 Homo sapiens cDNA: FLJ21962 fis, clone HEP05564. IncytePD:2507593 Hs.7567 12 0.0006621 4.440 ficolin (collagen/fibrinogen domain containing lectin) 2

(hucolin) IncytePD:4913537 Hs.54517 FCN2 9q34

0.0007516 5.028 kallikrein 6 (neurosin, zyme) IncytePD:1480159 Hs.79361 KLK6 19q13.3 0.0008444 5.321 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase,

polypeptide 6 IncytePD:2293978 Hs.159140 B4GALT6 18q11

0.000475 5.382 chemokine (C-C motif) ligand 7 IncytePD:4415304 Hs.251526 CCL7 17q11.2-q12

0.0008029 5.741 sciellin IncytePD:4554357 Hs.115166 SCEL 13q22 0.0007377 10.640 serine (or cysteine) proteinase inhibitor, clade B

(ovalbumin), member 2 IncytePD:557012 Hs.75716 SERPINB2 18q21.3

0.0001238 13.031 Small proline-rich protein SPRK [human, odontogenic keratocysts, mRNA Partial, 317 nt]

IncytePD:1599293 Hs.46320 1

0.000356 31.292 small proline-rich protein 3 IncytePD:2797764 Hs.139322 SPRR3 1q21-q22

Supplemental Table 1 - Home | Clinical Cancer...

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Clinical Cancer Researchclincancerres.aacrjournals.org/content/clincanres/4/1/local/front... · Accelerated mailing ofallAACRjournals toA.ACR members InJapan ... Clinical Cancer Research

Canadian Table of Frequency Allocations 2005

MCS 2005 Round Table

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Table of Contents - LTH · i 15 September 2005 Table of Contents Summary.....iv

Table of Contents Annual Report 2005-2006

Table 1.1: National Health Expenditures, 1980 – 2005 (1)