The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.
The document can mostly be used forward and backward. I tried to mark questionable stuff with (?).
If you want it to look pretty, steal some crayons and go to town.
Finally…
If you’re a gunner, buck up and do your own work.
Describe the morphology and size of a spirochete
Spirochetes are long but very narrow spiral shaped bacterial with internal flagella that
course down the side of the bacterium essentially between the inner and outer
membrane,
Name the spirochete visualization technique
Usually best visualized with dark-field microscopy. Antibody staining can also be
used.
Name three medically important spirochete species
TreponemaLeptospira
Borrelia
What disease is associated with treponema
Syphilis
What diseases are associated with Borrelia
Recurring feversLyme disease
What disease is associated with Leptospira
Leptospirosis
Name the stages of syphilis
PrimarySecondary
(Latent)Tertiary
Primary syphilis time frame
3 week incubation
Primary syphilis sx
Chancre at site of infection
Secondary syphilis time frame
Develops 2-8 weeks after chancre formation. Lasts days to weeks.
Secondary syphilis sx
Macular papular rash over body surface including soles and palms.
Latent syphilis sx
Essentially none. Low infectivity.May revert to secondary syphilis with high
infectivity.
Tertiary syphilis time frame
Typically develops in 15-20 years
Tertiary syphilis affected systems
NeurosyphilisCardiavascular syphilis
Neurosyphilis sx
Chronic meningitisBrain degeneration
Psychosis
Cardiavascular syphilis sx
Ascending and transverse aortic dilation due to endarteritis of the vasa vasorum
Congenital syphilis timeframe
Active infection after the 4th month
Congenital syphilis sx
Macular papular rash similar to secondary syphilis in adults