Rhabdomyolysis “New Mascot of First Responders?”€¦ · 19/05/2018 · (working in extreme...

14th Annual North State Pre-hospital Conference 2018 May 19, 2018

Presented by Bill Masten, Retired Los Angeles County Fire Chief 1

Rhabdomyolysis“New Mascot of First Responders?”

“RATTLESNAKE BITES AT 12 YEAR HIGH IN CALIFORNIA”

Rhabdomyolysis

What is Rhabdo?

Rhabdo= StriatedMyo= Muscle

Lysis= Breakdown

Rhabdomyolysis• Condition where injured muscles

release harmful substances into the bloodstream.

• These substances include potassium, phosphate, creatine kinase, and myoglobin.

• Large amounts of these substances may damage your kidneys and other organs.

RhabdomyolysisWhat are some causes?

• Crush Injury• Compartment Syndrome• Electrical Shock• Burns• Snake Bites & Spider Bites• Prolonged Physical Exertion

RhabdomyolysisRisk Factors

•Overexertion.

• Poor conditioning.

•Heat stress/stroke (working in extreme heat).

• Dehydration.

RhabdomyolysisRisk Factors

• Prescription medications such as cholesterol-lowering statins and antidepressants.

• Over-the-counter medications such as antihistamines.

• NSAID’s.

• Excessive caffeine intake.

RhabdomyolysisWhat can make you more susceptible?

• Pre-work out supplements.

• Energy Drinks.

• Hydration Strategy.

Rhabdomyolysis

Pre-Workout Supplements

RhabdomyolysisSports/Energy drink brand Caffeine (milligrams)• AMP Tall Boy Energy Drink, 16 ounces (oz.) 143• Enviga, 12 oz. 100• Full Throttle, 16 oz. 144• Full Throttle Fury, 16 oz. 144• Monster Energy, 16 oz. 160• No Name (formerly known as Cocaine), 8.4 oz. 280• Red Bull, 8.3 oz. 76• Rockstar, 16 oz. 160• SoBe Adrenaline Rush, 16 oz. 152• SoBe No Fear, 16 oz. 174

RhabdomyolysisEXHAUSTION

Rhabdomyolysis

SN’s

Sx’s

Rhabdomyolysis

Discolored UrineTea Cola

RhabdomyolysisEKG Progression of Hyperkalemia

Mild(5.5-6.5 mEq/L)

Moderate(6.5-8.0 mEq/L)

Severe( 8.0 mEq/L)

RhabdomyolysisHow is rhabdomyolysis treated?• Oral hydration.• IV fluids (0-9% normal saline)• Evacuation to ED for evaluation.

– Serum CPK (Creatine Phosphokinase)– Serum +K– Urine pH– Cardiac Monitor

Rhabdomyolysis

Physicians Handout

www.wildfiretoday.com/documents/Rhabdo_5_9_16.pdf

Rhabdomyolysis in Wildland FireA review of reported cases

RhabdomyolysisVariations of Myoglobin and CPK during Rhabdomyolisis

RhabdomyolysisPrevention is the key

• Conditioning• Hydration• Nutrition• Listening to your body

Rhabdomyolysis

Hydration Strategy

2 - waters

1– Hydration Solution

Rhabdomyolysis

Osmolarity is important for keeping proper electrolytic balance in the blood stream.

RhabdomyolysisReturning to work

Phase One1. Rest for 72 hours-oral hydration2. Sleep 8 hours each night3. Avoid excessive heat or cold4. Follow up within 72 hours to repeat blood and urine tests (CPK levels)

Phase Two1.If tests normal, begin light activity, no strenous

physical activity.2.Gradually increase light activity at your own pace

for one week.3.Follow up with PMD to assess full activity,

(asymptomatic and normal blood/urine values).

Phase Three1.Gradually return to full physical activity, monitor

for any return of symptoms.

High risk factors for Rhybdo reoccurrence•CPK levels over 100,000.•Heat stroke/exhaustion.•Kidney injury•Longer then normal recovery times.•Muscle cramps and tenderness frequency.•Suffered compartment syndrome.

Rhabdomyolysis

RhabdomyolysisTest Questions:

1. Rhabdomyolisis is caused by an injury to a long bone. (T) (F)

2. A sign of Rhabdo may be discolored urine. (T) (F)

3. Physical exertion can cause Rhabdo. (T) (F)

4. Energy drinks help prevent Rhabdo. (T) (F)

5. Rhabdo can cause high potassium levels. (T) (F)

RhabdomyolysisTest Questions:

1. Rhabdomyolisis is caused by an injury to a long bone. (T) (F)

2. A sign of Rhabdo may be discolored urine. (T) (F)

3. Physical exertion can cause Rhabdo. (T) (F)

4. Energy drinks help prevent Rhabdo. (T) (F)

5. Rhabdo can cause high potassium levels. (T) (F)

Rhabdomyolysis

Thank You!

Rhabdomyolysis “New Mascot of First Responders?”€¦ · 19/05/2018 · (working in extreme...

Documents

Rhabdomyolysis and Acute Kidney Injury (AKI)

Exertional rhabdomyolysis: physiological response or ...bmjopensem.bmj.com/content/bmjosem/2/1/e000151.full.pdf · Exertional rhabdomyolysis: physiological response or manifestation

A Case of Rhabdomyolysis Associated with Peginterferonapplications.emro.who.int/imemrf/Govaresh/Govaresh_2014_18_4_257... · A Case of Rhabdomyolysis Associated with Peginterferon

Rhabdo virus

Mascot Distiller - the key to automationproteomics.umd.edu/mascot/pdf/2003WKSHP1.pdf• Mascot Daemon 2.0 and later • Mascot Wizard • Your application The Windows application that

Rhabdomyolysis following coronary angiography: an unexpected … · 2021. 1. 12. · CASE REPORT Open Access Rhabdomyolysis following coronary angiography: an unexpected detection

Rhabdomyolysis complicating unrecognized hypophosphatemia ...downloads.hindawi.com/journals/cjgh/1999/376034.pdf · Rhabdomyolysis complicating unrecognized hypophosphatemia in an

Case Report Rhabdomyolysis due to Trimethoprim

Rhabdomyolysis: Making sense of the metabolic mayhem...Anaesthesia-induced rhabdomyolysis is a rare cause of rhabdomyolysis. It is most commonly seen during the administration of suxamethonium

Mascot Machine Review - SECRET of Mascot Machine

higherimpactent.com...SCHOOL MASCOT, TEXAS STATE NATIONAL CHAMPION MASCOT, OFFICIAL NCAA MASCOT, SAN ANTONIO MISSIONS MASCOT, ROUND ROCK EXPRESS MASCOT, SAN ANTONIO RAMPAGE MASCOT,

Hypophosphatemia and Rhabdomyolysis - JCI

Case rhabdo

Mascot Machine Review - Mascot Machine 100 bonus items

Work Capacity Test Compartment Syndrome/ Rhabdomyolysis ... · Work Capacity Test • Compartment Syndrome/Rhabdomyolysis Incident • Facilitated Learning Analysis 1 Learning Analysis

Rhabdomyolysis Review

RHABDO in EXTREME SURGERY

Day One Rhabdomyolysis Facilitated Learning Analysis

Rhabdomyolysis and Metabolic Myopathies 30 Gene Panel

Hyperthermia and rhabdomyolysis/CCM board review