Rebekah Ha Leah Shteynman Marlon Whitney The Cell Cycle

Rebekah HaLeah Shteynman Marlon Whitney

The Cell Cycle

•  period between cell divisions

• eukaryotic cells spend most time in

• includes g1, S, g2

Interphase

• first phase of mitosis

• duplicated chromosomes condense

• causes nucleolus to disappear

• spindle microtubules form

• originate from centrioles

• new pair forms during interphase near previous pair

Prophase

• middle phase/stage

• 2 kinetochores pull toward opposite poles

• While microtubules lengthen/shorted until chromosome lines up along equator with 1 kinetochore facing each pole 

• sister chromatids separate and are pulled to opposite poles of the cell

Metaphase

• another phase of mitosis, sister chromatids separate

• Allows each kinetochore move its chromosome pole ward, nibbling off end of attached microtubule

• Each pole has a copy of chromosome

• Polar microtubules grab one another overlapping at equator, lengthen + push on one another forcing poles of cell apart 

Anaphase

• a nuclear envelope forms around each group of chromosomes

• end stage

• Spindle microtubules disintegrate, nuclear envelope forms around each group of chromosomes

• Those revert to extended state, nucleoli reform

Telophase