Pyridinium Dichromate (PDC): The Corey-Schmidt Reagent

Formal total synthesis of (-)-balanol: a potent PKC inhibitor. Yaragorla, Srinivasarao; Muthyala, Ramaiah. Center for Orphan Drug Research, Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA. Tetrahedron Letters (2010), 51(3), 467-470.

Pyridinium dichromate (PDC) is a commercially available (and also readily prepared) salt of chromic acid that is soluble in many common organic solvents and useful in the oxidation of alcohols to aldehydes and ketones. It is less acidic than pyridinium chlorochromate (PCC), and thus more suitable for the oxidation of acid-sensitive substrates.

Pyridinium Dichromate (PDC): The Corey-Schmidt Reagent

Pyridinium Chlorochromate (PCC)

Corey-Suggs Reagent

Elias J. CoreyProfessor Emeritus, Harvard University

Nobel Prize Winner:

Shi Epoxidation

Oxone = Potassium Peroxymonosulfate =

Mechanism of the Shi Epoxidation

Chiral Dioxirane

Yian Shi Colorado State University

The chiral catalyst of the Shi Epoxidation is derived from the readily-available D-Fructose

Chiral Ketone Catalyst

Dimethyldioxirane(DMDO)

Trost Asymmetric Allylic Alkylation Reaction

Palladium -allyl complex

Barry TrostStanford University

Methods for Reduction of Azides to Amines